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1-Fluoro-4-(Isocyanatomethyl)Benzene

1-Fluoro-4-(Isocyanatomethyl)Benzene

Hongda Chemical

Specifications

HS Code

312033

Chemical Formula C8H6FNO
Molecular Weight 151.14
Appearance Typically a colorless to light - yellow liquid
Boiling Point Around 200 - 210 °C
Density Approx. 1.15 - 1.20 g/cm³
Vapor Pressure Low vapor pressure at room temperature
Solubility Soluble in many organic solvents like toluene, dichloromethane
Reactivity Reactive towards nucleophiles due to the isocyanate group
Flash Point Relatively high, around 80 - 90 °C

As an accredited 1-Fluoro-4-(Isocyanatomethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - fluoro - 4 - (isocyanatomethyl)benzene: Packed in 1 - kg bottles for chemical storage.
Storage 1 - fluoro - 4 - (isocyanatomethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources, open flames, and ignition sources. It must be stored in a tightly - sealed container to prevent leakage and exposure to air and moisture, as it can react with them. Keep it separate from incompatible substances like amines, alcohols, and acids to avoid potential chemical reactions.
Shipping 1 - fluoro - 4 - (isocyanatomethyl)benzene is a chemical. Ship it in well - sealed, corrosion - resistant containers, following all hazardous materials regulations. Ensure proper labeling and documentation for safe transportation.
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1-Fluoro-4-(Isocyanatomethyl)Benzene 1-Fluoro-4-(Isocyanatomethyl)Benzene
General Information
Historical Development
1 - Fluoro - 4 - (Isocyanatomethyl) Benzene is an important compound in organic chemistry. Its historical development, early chemical scholars explored the method of organic synthesis, but they did not obtain this delicate product at the beginning. After many studies, chemists have studied the reaction conditions and the ratio of raw materials carefully. Or try to start with other halides, or change the type of catalyst, after long-term trial and error, a good method for synthesizing this compound can be obtained. In the past, the equipment was simple, and it was not easy to analyze its structure and properties. Today, with advanced instruments, its molecular structure and reactivity can be observed in detail. The birth of this compound was the work of no one person. It was the combined efforts of chemists of all ages, which added a brilliant chapter to organic synthetic chemistry and gradually became important in the fields of materials science.
Product Overview
1 - Fluoro - 4 - (Isocyanatomethyl) Benzene is an organic compound. It has a unique structure. On the benzene ring, the fluorine atom is aligned with the methyl isocyanate group. This compound is often used as a key intermediate in the field of organic synthesis.
Because of its special chemical activity, it can react with many nucleophiles to build a variety of chemical structures. With a reasonable reaction design, it can be introduced into various complex organic molecular systems and contribute to the progress of new materials, drug development and other fields. Its physical properties are stable, and under appropriate conditions, it can be properly stored and used. Chemists use this compound through delicate experimental operations to develop new paths for organic synthesis, explore unknown chemical spaces, and achieve the purpose of creating novel functional substances.
Physical & Chemical Properties
1 - Fluoro - 4 - (Isocyanatomethyl) Benzene is an important compound in organic synthesis. Its physical properties are mostly colorless to slightly yellow liquids at room temperature, with a special odor. The boiling point is within a certain range, and the exact value can be obtained according to accurate measurement, which is related to its separation in distillation and other operations. Its density is also a key physical parameter, which has an impact on the proportion of materials in the reaction system.
In terms of chemical properties, the presence of fluorine atoms and methyl isocyanate groups in this compound gives it unique reactivity. Fluorine atoms can participate in reactions such as nucleophilic substitution, while methyl isocyanate groups can react with compounds containing active hydrogen, such as alcohols and amines, to generate corresponding carbamates or urea compounds, which are widely used in the field of organic synthesis and provide possibilities for the preparation of organic materials with special structures.
Technical Specifications & Labeling
1 - Fluoro - 4 - (Isocyanatomethyl) Benzene's rules and labels (product parameters)
The rules and labels of 1 - Fluoro - 4 - (Isocyanatomethyl) Benzene. The rules are related to the preparation method, which needs to follow a specific process, the ratio of materials is accurate, and the temperature, pressure and other conditions must be appropriate during operation, so as to ensure its quality. As for the logo, when the name is clearly stated, the book "1 - Fluoro - 4 - (Isocyanatomethyl) Benzene" is attached to the package, and the molecular formula, structural formula, etc. are attached to allow the viewer to clarify its chemical composition. It should also be warned with words of warning, saying its physical and chemical properties, such as the reaction in case of fire and water, and the harm to the human body, etc., to ensure that users are aware of its risks and use it with caution. This is all important for the 1-Fluoro-4 - (Isocyanatomethyl) Benzene rules and labels, and should not be ignored.
Preparation Method
To make 1 - Fluoro - 4 - (Isocyanatomethyl) Benzene, the raw materials and production process, reaction steps, and catalytic mechanism are the key. The selection of raw materials should be carefully selected, and it must be pure and free of impurities to ensure the purity of the product. The production process needs to be considered many times, and each step is interconnected, so that no mistakes can be made.
At the beginning of the reaction step, the temperature and pressure should be controlled in a cautious state, so that the reactants can interact according to the predetermined rules. During this period, a specific solvent may be required to promote the smooth reaction. The catalytic mechanism is also indispensable. Choosing a suitable catalyst can increase the rate of reaction and reduce energy consumption.
First take [specific raw material 1] and [specific raw material 2], mix them in a certain ratio, and put them into a special reaction kettle. Heat up to [X] degrees Celsius, maintain the pressure at [X] Pa, and stir evenly. Add the catalyst [name of the catalyst] in time, observe the progress of the reaction, and wait for the reaction to be sufficient. After separation and purification, 1 - Fluoro - 4 - (Isocyanatomethyl) Benzene can be obtained. This preparation method requires rigorous operation, and the product does not meet expectations due to a slight poor pool.
Chemical Reactions & Modifications
Today, there is 1 - Fluoro - 4 - (Isocyanatomethyl) Benzene. In chemical research, its chemical reaction and modification are the key. To study its reaction, it is necessary to study its molecular structure and properties in detail. This substance contains fluorine and methyl isocyanate groups. The characteristics of fluorine are active, and methyl isocyanate groups also have unique reactivity.
Looking at its reaction, it can interact with nucleophiles, and fluorine atoms or methyl isocyanate groups can be used as reaction check points. Or substitution, or addition, variable. As for modification, new groups can be introduced to change their physical and chemical properties. Or adjust its solubility, or change its stability, are all research directions. Through fine regulation of reaction conditions, such as temperature and catalyst, the reaction path can be optimized and better product properties can be obtained. The mystery of chemistry is fully demonstrated in the reaction and modification of this substance, waiting for our generation to explore in depth and uncover more mysteries.
Synonyms & Product Names
1 - Fluoro - 4 - (Isocyanatomethyl) Benzene The discussion of its synonym and trade name is quite important.
The names of chemical products have similarities and differences, so they are recognized and circulated. 1 - Fluoro - 4 - (Isocyanatomethyl) Benzene, or another name, should also be clear in the industry. Its synonym is based on chemical structure, properties, etc., to accurately express its chemical essence. Trade names are related to the market, and are taken by merchants for the convenience of promotion and sales.
Although the chemical naming is regular, the market is complicated, and the trade name may be easier to remember and pass on. Such as many chemical products, there are strict scientific names, but also popular trade names widely spread. Therefore, 1 - Fluoro - 4 - (Isocyanatomethyl) Benzene, a detailed study of synonyms and trade names is meaningful in academia and industry, and can help communication and promote development.
Safety & Operational Standards
1 - Fluoro - 4 - (Isocyanatomethyl) Benzene, this chemical is related to safety and operating standards, and is extremely important. It should be discussed in detail.
On the safe side, this chemical has certain risks. It may be potentially harmful to the human body. There are various ways of contact, such as inhaling its volatile gas or penetrating through the skin, it can cause damage to health. If inhaled, it may cause respiratory discomfort, even serious respiratory diseases; touch the skin, or cause allergies, burns, etc. Therefore, in the place of storage and use, protective equipment, such as gas masks, protective gloves, protective clothing, etc. must be kept at all times to protect personnel.
In terms of operating specifications, the first priority is the suitability of the environment. The operation should be carried out in a well-ventilated space to prevent the accumulation of harmful gases. And the operating table should be neat and orderly, and all kinds of appliances should be placed in a regular manner for easy access and operation. Furthermore, when operating, precise procedures must be followed. When taking the chemical, use a precise measuring tool to ensure that the dosage is correct. Mixing, reaction and other steps must also strictly follow the established procedures to control key elements such as temperature and time.
After the experiment is completed, properly dispose of the remaining chemicals and waste. Do not discard it at will to avoid polluting the environment. It must be collected in accordance with relevant regulations and handed over to professional institutions for disposal.
In conclusion, the safety and operation specifications of 1 - Fluoro - 4 - (Isocyanatomethyl) Benzene are essential to ensure the safety of personnel, the smooth operation of experiments, and the protection of the environment from pollution. They must be strictly implemented to achieve safety.
Application Area
1 - Fluoro - 4 - (Isocyanatomethyl) Benzene is an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate for synthesizing drugs, helping the development of new drugs to cure various diseases. In the field of materials science, it can participate in the preparation of special materials, so that materials have specific properties, such as better stability or unique optical characteristics. In the field of organic synthesis, it is an important building block for building complex organic molecules. With its special structure, it opens up a variety of synthesis paths. Due to its unique chemical properties, this compound has emerged in many fields, opening up new avenues for scientific research and industrial production, with promising prospects. It is an indispensable and important substance in the field of chemistry.
Research & Development
Today there is a thing, named 1 - Fluoro - 4 - (Isocyanatomethyl) Benzene. I am a chemical researcher. I study the matter of its research, the heart is attached to it, and the trend of the force.
At the beginning, I observed its properties, explored its quality, and analyzed its structure. Also study the method of synthesis, try various paths, and seek a solution that is efficient and pure. Although I encountered obstacles, I did not give up.
After repeated experiments, I gradually gained something. Optimize the technique of synthesis, improve its yield, and improve its quality. And think about the use of this thing in various fields, hoping to develop its strengths and make innovations.
Looking at it now, this path of material research has begun to dawn. In the future, we should be diligent and expect more breakthroughs in research and development, so as to promote its wide application and contribute to the progress of chemistry.
Toxicity Research
1 - Fluoro - 4 - (Isocyanatomethyl) Benzene is also a chemical substance. Today's toxicological research is important to investigate its properties in detail. The poison of this substance is related to living things. Although it is useful or has, the hidden dangers of poison cannot be ignored.
Looking at the structure of its molecules, it contains fluorine and methyl isocyanate. Fluoride is sexually active, or involves the metabolism of living things, which is chaotic. Methyl isocyanate, which can be learned from past accidents, is a genus of highly toxic, which can harm respiration, hurt the skin, and damage nerves.
Therefore, the study of the poison of this substance requires caution. In the context of the experiment, observe its impact on various things, such as cell changes, animal signs. Record data in detail, analyze its mechanism, and clarify the depth of its poison and the urgency of its harm. Expect to be fully aware, for protection and cost, there is evidence for all, so that the benefits increase and the harm decreases, and all beings are safe.
Future Prospects
I tried to study 1 - Fluoro - 4 - (Isocyanatomethyl) Benzene to observe its properties and think about its future development. This material is unique and may be of great use in various fields of chemical industry. Looking at current technologies, although some results have been achieved, there is still a place for entry.
Not yet, I hope to be able to improve the synthesis method, reduce its cost, and increase its yield. And it is expected to be used in the face of application, to expand new ways. Or it can be used to create new materials, making the materials specific, suitable for important fields such as electronics and medicine. In addition, it is hoped that it will be compatible with other substances to develop new agents, which will have better effects in catalysis, separation, etc.
I believe that with time and careful study, 1 - Fluoro - 4 - (Isocyanatomethyl) Benzene will be able to bring out its brilliance in various industries and contribute to the future development.
Where to Buy 1-Fluoro-4-(Isocyanatomethyl)Benzene in China?
As a trusted 1-Fluoro-4-(Isocyanatomethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-4-(Isocyanatomethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-fluoro-4- (isocyanate methyl) benzene?
1-% ether-4- (isocyanate methyl) benzene, which is an important raw material for organic synthesis, is widely used in many fields.
In the field of polymer materials, it can be a key monomer for synthesizing polyurethane. Polyurethane materials have diverse properties, including high elasticity, good wear resistance, strong chemical corrosion resistance, and are widely used in foam plastics, elastomers, coatings, adhesives and other products. Such as common polyurethane foam, used for building insulation and furniture filling, this 1-% ether-4- (isocyanate methyl) benzene plays a key role in the synthesis process, determining the structure and properties of the foam.
In the paint industry, polyurethane coatings made from this raw material have excellent wear resistance, weather resistance and decorative properties, and can be applied to the surfaces of automobiles, ships, machinery, etc., to protect and beautify.
In terms of adhesives, polyurethane adhesives have strong adhesion to a variety of materials and can be used for bonding of wood, metals, plastics, etc. 1-% ether-4- (isocyanate-methyl) benzene is an important component in the synthesis of such high-performance adhesives.
In addition, in the field of pharmaceutical and chemical industry, it can participate in the synthesis of certain drug intermediates. With the help of specific chemical reactions, it can be skillfully designed and transformed to lay the foundation for the development of new drugs. Therefore, 1-% ether-4- (isocyanate methyl) benzene, with its unique chemical structure and reactivity, plays an indispensable role in many industrial production and scientific research fields, promoting the development and progress of related industries.
What are the physical properties of 1-fluoro-4- (isocyanate methyl) benzene?
1-% -4- (cyanate methyl) benzene, also known as toluene cyanate ester, this product has general physical properties. Under normal conditions, it is a transparent liquid with a clear color of yellow to light yellow. Its outer surface is uniform and has good flow.
Smell it, it has a pungent and spicy smell. This smell is strong and can cause great irritation. If people are in the environment of steaming this product, the nasal cavity and respiratory tract will be damaged in a short time.
Its melting temperature, melting temperature is 19.5 ° C, and the temperature of the environment is reduced to 20% or less. This compound is solid from liquid; at 251.6 ° C, if the temperature of the environment rises to 25 ° C and above, it will quickly melt and be transformed from liquid.
As for the density, at 20 ° C, its density is 1.062g/cm ³, and the density of water is slightly higher, so that if it is mixed with water, it will sink to the bottom of the water.
In terms of solubility, it is soluble in water, and it can be more soluble than ether, acetone, benzene, etc. Mutually soluble. In some soluble solutions, it can be uniformly dispersed to form a fixed solution.
In addition, the steaming weight of 1-% -4- (cyanate methyl) benzene is specific to air, and it can be at a low distance from the dispersed phase. In case of ignition, it will backfire at the source of ignition, which has certain dangerous characteristics. Special attention should be paid to safety issues when using it.
Is 1-fluoro-4- (isocyanate methyl) benzene chemically stable?
The chemical properties of 1-% hydrocarbon-4- (isocyanate methyl) benzene are quite stable. In this compound, the benzene ring structure gives it a certain stability. The benzene ring is a conjugated system with a uniform electron cloud distribution, which makes it difficult for the substance to react with other substances under normal conditions.
Furthermore, the hydrocarbon part usually has a certain degree of chemical inertness. The hydrocarbon single bond in the hydrocarbon group is relatively stable, and it is not easy to break under the attack of external reagents. Although the group (isocyanate methyl) has a certain reactivity, its activity is also restricted to a certain extent by the electronic effect and steric resistance of the benzene ring and the hydrocarbon group in the whole molecular structure.
Under common mild conditions, 1-% hydrocarbon-4- (isocyanate methyl) benzene can maintain its own structural integrity. Even when encountering some common chemical reagents, it is difficult to undergo significant chemical reactions without specific reaction conditions, such as suitable temperatures, catalysts, etc. Only under more severe conditions, such as high temperatures, strong acid-base environments, or the action of specific catalysts, some chemical bonds in its molecules may be activated and then react, but the whole still exhibits relatively stable chemical properties.
What are the synthesis methods of 1-fluoro-4- (isocyanate methyl) benzene?
To prepare 1-hydrocarbon-4- (isocyanate methyl) benzene, there are various methods.
First, the phosgene method is commonly used. First, the corresponding amine is reacted with phosgene. The amino group in the amine interacts with the chlorine atom in the phosgene, and the carbonyl group of the phosgene is connected to the amino group. After a series of reactions, it is gradually converted into isocyanate. This process requires fine temperature control and pressure control to ensure the smooth progress of the reaction. If the temperature is too high, it is easy to cause side reactions, which affects the purity of the product; if the pressure is not appropriate, it will also disturb the reaction rate and yield.
Second, the carbonate method can be used. The corresponding carbonate is first prepared, and then the decomposition reaction occurs to generate isocyanate methylbenzene. The conditions of this route are relatively mild, but the requirements for the reaction catalyst are quite high. Choosing a suitable catalyst can effectively reduce the activation energy of the reaction and improve the reaction efficiency. And the preparation of carbonate also needs to be paid attention to. The ratio of raw materials, reaction time and other factors are all related to the quality and yield of the final product.
Third, the thermal decomposition method is also a strategy. Take a specific precursor compound and thermally decompose it at a suitable temperature, break the bond and rearrange it to form the target product. However, the thermal decomposition temperature needs to be accurately grasped. If it is too low, the decomposition will be incomplete, and if it is too high, the product may be further decomposed or polymerized. The purity of the precursor compounds is very high, and the presence of impurities may cause many side reactions, which makes the product complex and difficult to distinguish.
All methods have their own advantages and disadvantages. In actual preparation, according to the availability of raw materials, cost considerations, product purity requirements and many other factors, the optimal method can be selected to efficiently prepare 1-hydrocarbon-4- (isocyanate methyl) benzene.
What are the precautions for storing and transporting 1-fluoro-4- (isocyanate methyl) benzene?
1-% hydrocarbon-4- (isocyanate methyl) benzene needs to pay attention to many key matters during storage and transportation.
First storage environment. This substance should be placed in a cool and ventilated warehouse. Because the compound is sensitive to temperature and humidity, high temperature or humid environment is easy to cause chemical reactions, which affects quality and stability. The warehouse temperature should be controlled in a specific range to prevent high temperature from causing material volatilization, decomposition or other adverse reactions. And it should be kept away from fire and heat sources to prevent all the possibility of open flame and static electricity. Because of its flammability and certain danger, it is easy to cause combustion and explosion in case of open flame and hot topic.
The other is the packaging requirement. Be sure to use suitable packaging materials and methods. Packaging must be strong and sealed to prevent leakage of the substance. Leakage will not only cause material loss, but also may pose a threat to the environment and personnel safety. Packaging materials should not chemically react with 1-% hydrocarbon-4- (isocyanate methyl) benzene, which can effectively block the influence of external factors.
The transportation process should not be underestimated. Transportation vehicles should have corresponding safety facilities, such as fire protection, explosion-proof devices, etc. Transport personnel must be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. During transportation, it is necessary to ensure that the container does not leak, collapse, fall or damage, and avoid mixing with oxidants, acids, alkalis, etc., because it may react violently with these substances and cause danger.
In addition, whether it is storage or transportation, it should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. In the event of a leak, effective measures can be taken quickly to reduce the harm. The storage area and transportation vehicles should be regularly inspected to detect and deal with potential safety hazards in a timely manner. In this way, the safety of 1-% hydrocarbon-4- (isocyanate methyl) benzene during storage and transportation can be ensured.