Hongda Chemical
Products
Home  /  Products  / 

1-Fluoro-4-Chlorobenzene

1-Fluoro-4-Chlorobenzene

Hongda Chemical

Specifications

HS Code

645279

Chemical Formula C6H4ClF
Molar Mass 116.547 g/mol
Appearance Colorless liquid
Boiling Point 102 - 103 °C
Melting Point -34 °C
Density 1.192 g/cm³
Flash Point 11 °C
Solubility In Water Insoluble
Vapor Pressure 11.9 hPa (20 °C)
Logp 2.57
Refractive Index 1.478 (20 °C)

As an accredited 1-Fluoro-4-Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottle of 1 - fluoro - 4 - chlorobenzene, securely sealed for chemical storage.
Storage 1 - Fluoro - 4 - chlorobenzene should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames as it is flammable. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive substances to avoid potential chemical reactions. Label the storage clearly for easy identification and safety.
Shipping 1 - fluoro - 4 - chlorobenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous material shipping regulations. Temperature control may be required during transit to prevent any potential reactions.
Free Quote

Competitive 1-Fluoro-4-Chlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

1-Fluoro-4-Chlorobenzene 1-Fluoro-4-Chlorobenzene
General Information
Historical Development
1 - Fluoro - 4 - Chlorobenzene is also a chemical substance. It has been traced back to its origin for a long time. In the past, chemists studied the physical properties and chemical properties, and began to discover this substance. At the beginning, the road of exploration was bumpy, and everyone tried it in different ways, hoping to understand its characteristics. With the passage of time and the advance of science and technology, the method of its production has become more and more refined. In the past, it may have required difficult steps and took a lot of time and effort, but now it is done by ingenious methods, and the efficiency has doubled. Scholars have delved deeper into its reaction mechanism to understand its role in various chemical processes. In the field of organic synthesis, it has gradually become a key material, helping to create all kinds of useful things. From ancient times to the present, the development of 1-Fluoro-4-Chlorobenzene has been an important item in chemical exploration, laying the foundation for more new discoveries and new applications in the future.
Product Overview
1 - Fluoro - 4 - Chlorobenzene is an organic compound. Its color is clear and transparent, and it has a special smell. This compound is formed by combining fluorine and chlorine atoms with benzene ring. Benzene ring, hexagonal carbon ring structure, stable properties. Fluoro and chlorine atoms are connected to specific positions in the benzene ring, resulting in unique chemical activity.
1 - Fluoro - 4 - Chlorobenzene has a wide range of uses in the field of organic synthesis. It can be used as an intermediate and participates in the construction of a variety of complex organic molecules. Because of its fluorine and chlorine atoms, it can endow the product with special properties, such as enhancing the stability of the compound and regulating its solubility. In medicinal chemistry, it may help to create new drugs with unique pharmacological activities; in materials science, it can also provide a basis for the development of materials with special properties. Its reactivity can vary depending on conditions, and chemists can use factors such as temperature and catalysts to regulate its reaction to achieve the desired synthesis target.
Physical & Chemical Properties
1 - Fluoro - 4 - Chlorobenzene is an organic compound, and its physicochemical properties are particularly important. Looking at its physical properties, it is a colorless and transparent liquid at room temperature, with a special odor. The boiling point is about 117 to 119 degrees Celsius, which makes it possible to realize the transformation of gas and liquid under specific temperature conditions, which is of great significance in operations such as separation and purification. Its density is slightly higher than that of water, about 1.25 grams per cubic centimeter, causing it to sink to the bottom when mixed with water.
Discussing chemical properties, the presence of fluorine and chlorine atoms in this compound gives it unique reactivity. Due to the strong electronegativity of fluorine atoms, the electron cloud density of benzene ring decreases, making it more prone to electrophilic substitution reactions. Although the electronegativity of chlorine atom is weaker than that of fluorine, it can also affect the reactivity. In many organic synthesis reactions, 1-Fluoro-4-Chlorobenzene can be used as a key intermediate to participate in the construction of more complex organic molecular structures, which is widely used in the fields of medicine, pesticides and so on.
Technical Specifications & Labeling
1 - Fluoro - 4 - Chlorobenzene is an organic compound, and its technical specifications and labeling (product parameters) need to be carefully considered.
According to its properties, it should be colorless and transparent, and there should be no visible impurities. The smell should be fresh and free of pungent odors. This is the main point of preliminary discrimination.
When it comes to purity, it must meet very high standards to ensure high quality. The content of impurities should be strictly controlled and must not exceed the specified limit.
In terms of labeling, key information such as name, chemical formula, content, production batch must be clearly marked on the packaging. In this way, users can accurately know the product details for proper use. This is the essence of the 1 - Fluoro - 4 - Chlorobenzene specification and logo, and should not be ignored.
Preparation Method
To prepare 1 - Fluoro - 4 - Chlorobenzene, the raw materials, production process, reaction steps and catalytic mechanism are as follows.
First take an appropriate amount of chlorobenzene as raw material, which is the starting material of the reaction. In a special reactor, add an appropriate amount of potassium fluoride, supplemented by a phase transfer catalyst, this agent can promote the effect of ion exchange between the two reactants. When heated to a suitable temperature, about 180 - 200 ° C, this temperature can make the reaction proceed orderly and efficiently.
The reaction steps are as follows: The chlorine atom in chlorobenzene is attacked by the fluorine ion in potassium fluoride, and the two undergoes a substitution reaction. Due to its strong nucleophilicity, fluorine ions can replace chlorine atoms on chlorobenzene to generate 1-Fluoro-4-Chlorobenzene and potassium chloride.
The catalytic mechanism is that the phase transfer catalyst can make potassium fluoride originally in the aqueous phase more easily contact with chlorobenzene in the organic phase, reduce the activation energy of the reaction, speed up the reaction rate, and improve the product formation efficiency, so 1-Fluoro-4-Chlorobenzene can be obtained.
Chemical Reactions & Modifications
1 - Fluoro - 4 - Chlorobenzene is an organic compound, and its preparation is related to chemical reaction and modification. In the past, we have observed its synthesis method and relied on halogenation. However, the traditional halogenation reaction often encounters the dilemma of poor selectivity.
At the beginning, benzene was used as the substrate, and fluorine and chlorine atoms were introduced. The reaction conditions were harsh, and side reactions were frequent, resulting in the purity of the product difficult to achieve ideal. We then thought about improving the method to improve the selectivity and efficiency of the reaction.
After repeated experiments, it was found that the intervention of a specific catalyst could make the reaction more directional. If metal-containing complexes are used as catalysts, the reaction path can be effectively regulated, so that fluorine and chlorine atoms fall precisely at specific positions in the benzene ring, resulting in 1-Fluoro-4-Chlorobenzene, and the yield is increased.
Furthermore, optimizing the temperature, pressure and other conditions of the reaction also has a great impact on the formation of the product. After many explorations, suitable reaction parameters were found, which made the reaction and modification of this chemical product more perfect, laying a solid foundation for its subsequent application.
Synonyms & Product Names
1 - Fluoro - 4 - Chlorobenzene, this substance is also the synthetic product of chemistry. Its synonymous name, known as p-fluorochlorobenzene. In the field of industry and scientific research, it has a wide range of uses.
In chemical production, it is an important raw material for the preparation of a variety of fine chemicals. Or used in the synthesis of pharmaceuticals, to help cure diseases; or used in the manufacture of pesticides, to protect the growth of crops.
The name of its product is also known in the city. However, no matter what the name is, it is all the same substance. Chemists explore its properties, observe the laws of its reaction, and study it tirelessly in order to expand its use.
This 1 - Fluoro - 4 - Chlorobenzene, with its unique chemical properties, has shown its effectiveness in many fields and has made great contributions to human production and life.
Safety & Operational Standards
1 - Fluoro - 4 - Chlorobenzene is a chemical substance. It is crucial to the safety and operation of this substance. I will describe it in detail today.
Anyone who comes into contact with 1 - Fluoro - 4 - Chlorobenzene must strictly follow the procedures. Handle this substance in a well-ventilated place to ensure that the foul gas dissipates quickly and does not accumulate in the room, endangering the person. And protective equipment, such as special clothing, gloves and masks, must be worn to protect the skin, hands, feet and mouth and nose from harm.
This substance is strong, or toxic, or flammable, or rotten. When storing, it is advisable to keep it in a cool and dry place, away from fire and heat sources, to prevent it from exploding. And when it is stored separately from other things, avoid it from touching and causing harm.
If you accidentally touch it, quickly rinse it with water to remove its contamination. If it enters your eyes, you must rinse it with water for a long time urgently, and seek medical attention as soon as possible. If you eat it by mistake, do not urge vomiting, and seek medical help immediately.
When using it, precise operation is essential, and do not overflow. After use, properly dispose of the residue, and do not discard it at will to avoid polluting the environment.
In short, although 1-Fluoro-4-Chlorobenzene is useful in chemical industry, it is also risky. When we operate, we must prioritize safety and strictly abide by the rules of operation, so as to avoid disasters in the future, protect our health, and protect the tranquility of the environment.
Application Area
1 - Fluoro - 4 - Chlorobenzene is also an organic compound. Its application field is quite wide. In medicinal chemistry, it can be a key intermediate for the synthesis of special drugs, helping to create good drugs for specific diseases and benefit patients. In the field of materials science, it can participate in the synthesis of high-performance materials, so that the materials have unique physical and chemical properties, such as enhancing the stability and functionality of materials to meet the needs of different scenarios. In the field of pesticide research and development, it can be used as an active ingredient to improve the insecticidal and bactericidal efficiency of pesticides and protect the growth of crops. And it is often an important starting material or reagent in organic synthesis reactions. With its unique chemical structure, it opens up a variety of reaction paths, providing strong support for chemists to explore new substances and expand the boundaries of the chemical world.
Research & Development
1 - Fluoro - 4 - Chlorobenzene, the research and development of this product is related to the progress of chemistry. I have been studying this product for a long time. The method of its synthesis took a lot of thought. At the beginning, I tried all kinds of paths, but all encountered obstacles. After repeated tests, I finally got a method, which can produce a relatively pure 1 - Fluoro - 4 - Chlorobenzene.
Looking at its properties, it has unique physical and chemical properties. The physical properties are stable, but in a specific chemical environment, the reactivity is quite high. This property makes it have application potential in many fields.
Looking to the future, the development prospects of 1 - Fluoro - 4 - Chlorobenzene are broad. It can be used in fine chemicals to prepare high-end chemicals. It is also expected to contribute to the research and development of new drugs in the field of medicine. I should make unremitting efforts to expand its application and contribute to the development of chemistry.
Toxicity Research
1 - Fluoro - 4 - Chlorobenzene toxicity study
Modern chemical refinement, the variety of substances is becoming more and more diverse, 1 - Fluoro - 4 - Chlorobenzene is also one of the chemical products. Our generation takes toxicity research as a service to investigate the properties of this product in detail.
1 - Fluoro - 4 - Chlorobenzene has a unique molecular structure, fluorine and chlorine atoms are connected to the benzene ring. This structure may cause it to have special chemical activity, which in turn affects the biological system. From an experimental point of view, it often has adverse effects on the tested organisms. When it enters the animal body, it can disturb its physiological function and damage the organs.
At the cellular level, 1-Fluoro-4-Chlorobenzene or breaks the integrity of the cell membrane, disrupting the signal transduction in the cell and causing imbalance in cell metabolism. However, the depth of its toxicity is also related to the dose and duration of exposure. The higher the dose and the longer the exposure, the more obvious the harm.
We should continue to study and clarify the details of its toxicology, as the basis for protection and application, to avoid its harm and use its benefits, so that chemical products can benefit the world and avoid disasters.
Future Prospects
Husband 1 - Fluoro - 4 - Chlorobenzene is also a thing of transformation. In today's world, its use is not enough, and it involves a lot of work, and it is also difficult to study.
Looking at the future, the hope of its development is great. Those who are scientific must study its nature and explore its reasons, so that the quality of this thing can be improved and the effect can be improved. Or in the new system, the material obtained is obtained, and the disease is saved; or in the refined chemical industry, it can be made into a special product and increased.
With the increasing technology, the method of research and development will also be more and more effective. Or we can make this thing more economical and more efficient to meet our needs. In the future, there may be a way, but we must strive to make 1 - Fluoro - 4 - Chlorobenzene work in the world. Its great power will benefit the people, and the limited scenery will be developed in the future.
Where to Buy 1-Fluoro-4-Chlorobenzene in China?
As a trusted 1-Fluoro-4-Chlorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-4-Chlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-fluoro-4-chlorobenzene?
The main use of "1-Jiang-4-Sea Clam" is particularly important. Sea Clam, which has always been a seafood treasure, is very useful in food, medicinal use, and cultural affairs.
As far as the food is concerned, the meat of sea clam is plump, tender and smooth, and the taste is incomparably fresh and mellow. Its cooking methods are various, or boiled, or fried, or stewed, each with a wonderful taste. Take the method of cooking as an example, take the meat of sea clam, place it in a boiling soup, and then heat it up a little. With fresh juice, the meat of the clam is tender and tender. When you enter it, it is delicious and fragrant, and it is really a delicacy. The beauty of its taste has been praised by many diners. It is often a eye-catching delicacy at banquets, which shows its important position in the diet.
When it comes to medicinal uses, sea clams are rich in a variety of nutrients and beneficial substances. In mussel meat, the content of protein and trace elements is quite abundant, which has the effect of nourishing yin and nourishing deficiency, clearing heat and detoxifying. Ancient physicians often used sea clams as medicine to treat the disease of exhaustion and heat poisoning. In case of people with yin deficiency, hot flashes and night sweats can be seen, and sea clams can be combined with various medicines to achieve the effect of nourishing yin, conditioning the body and restoring health.
Sea clams also have profound cultural implications. In coastal areas, it is often a symbol of fishermen's beliefs and is regarded as a auspicious thing. Fishermen go out to sea to work and pray to catch sea clams and return with a full load, implying a prosperous and happy life. And in traditional folk activities, the image of sea clams is often found in various handicrafts, paintings, etc., carrying the people's yearning and expectation for a better life, and inheriting the unique cultural memory of the region.
To sum up, "1-Jiang-4-Sea clams", whether eaten as delicious, used as good medicine, or as a symbol of culture, have shown value that cannot be ignored, and are of great use to people's livelihood.
What are the physical properties of 1-fluoro-4-chlorobenzene?
Water, that is, mercury, is a common element of gold. Its physical properties are special.
First of all, under the constant temperature and force, water is liquid, which is its most characteristic. Many metals are often different in the world. Water is like a flowing river, smooth and smooth. Its flow is good, and it can be easily stretched and extended on a plane.
In addition, its color and light, the color of water is white, shining, like the moonlight, the reflected light is very bright, so it shines brightly under the light, attracting people's attention.
And density, the density of water is large, 13.6 grams/cubic centimeter, and the weight of many ordinary things is heavy. If an object is thrown into water, if its density is less than that of water, it can float on it. This property also makes water useful in certain quantities and fractions.
The quality of water cannot be ignored either. Its good performance makes it possible for water to flow in it, so it is often used in fields such as appliances and watches. However, in the same way, its performance is not good in terms of performance, and it is slightly more colorful than that of some good metals.
In addition, the melting temperature of water is very low, -38.87 ° C, so it can still maintain liquid performance in a low temperature environment. And its boiling temperature is 356.6 ° C, when the boiling temperature rises to the boiling temperature, the water will quickly vaporize and melt from the liquid.
In addition, the physical properties of water make it useful in different technologies and fields. However, due to its toxicity, it should be used with caution.
What are the chemical properties of 1-fluoro-4-chlorobenzene?
Lead is one of the hardware. It is soft and heavy in nature, blue and gray in color, and often appears in ore veins. The chemical properties of lead are fascinating to study.
Lead has strong corrosion resistance. In normal environments, lead gradually reacts with oxygen in the air, forming a thin layer of lead oxide on the surface. This layer of oxide acts as a strong shield, which can prevent further oxidation of lead, so lead can be stored outside for a long time and less damaged. For example, in the past, many roof drainage tanks were mostly made of lead. After years of wind and rain, they could still maintain their shape and use it to their fullest extent, all relying on this anti-corrosion property.
The chemical activity of lead is relatively less active. In the order of metal activity, after lead occupies hydrogen, it is difficult for lead to react with dilute acids such as dilute hydrochloric acid and dilute sulfuric acid at room temperature to generate hydrogen gas. When encountering strong oxidizing acids, such as nitric acid, lead will chemically react with it. If it encounters dilute nitric acid, lead nitrate will be formed, and it will be accompanied by the escape of nitric oxide gas. This reaction shows that lead can chemically change with acids under specific conditions.
Furthermore, lead can combine with many non-metallic elements. When encountering sulfur, lead easily reacts with sulfur to form lead sulfide. Lead sulfide is black in color and is commonly found in some forms of lead ore. This combination reaction occurs from time to time during the formation of minerals in nature, and has a deep impact on the morphology and distribution of lead ore.
Also, lead compounds have different properties. For example, lead hydroxide, which is amphoteric, can not only react with acids to form corresponding lead salts and water, but also react with strong bases to form lead salts and water. This property makes lead hydroxide have its unique uses in the chemical industry and scientific research fields.
The chemical properties of lead have far-reaching implications in many fields. In the metallurgical industry, lead's corrosion resistance and relatively stable chemical properties make it an important component of many alloys; in chemical production, lead compounds are widely used in pigments, batteries and other industries. However, lead and its compounds are highly toxic and pose great harm to human health and the environment. When used, one must be cautious.
What is the preparation method of 1-fluoro-4-chlorobenzene?
To prepare 1-fen-4-bromonaphthalene, the method is as follows:
Take the naphthalene as the base first, and the naphthalene has a dicyclic aromatic compound. Use bromine as the brominating agent, and iron or iron salt as the catalyst. Place the naphthalene in a suitable reactor, and pass dry gas inside to prevent the disturbance of impurities. Slowly add bromine solution, and add a little iron filings at the same time to promote the speed of the reaction.
The reaction of bromine and naphthalene should be controlled at its temperature. At the beginning, the reaction is slightly slow and gradually intense. Use water or other cooling methods to stabilize its temperature to prevent it from overheating and causing side reactions. On the capillary ring, bromine is easily added to the α position. However, if the temperature is too high or the time is too long, there is also the possibility of substitution of the β position. Therefore, temperature control is necessary.
After the reaction is completed, the product is mixed in the system. Wash with water first, except for the untreated bromine and iron salts. Bromine water is soluble and can be removed. Then extract it with an organic solvent, such as ether, dichloromethane, etc., so that the product is concentrated in the organic phase.
The organic phase is dried with anhydrous sodium sulfate or magnesium sulfate to absorb its moisture. After distillation, the organic solvent is first removed, and then the temperature is controlled to steam out 1-fen-4-bromonaphthalene. Because the boiling point of the product is fixed, according to its physical properties, a pure product can be obtained
The method of making this product focuses on temperature control, anti-impurities, and refining steps. If one step is wrong, the product will be impure and the yield will be low, so it needs to be done carefully.
What are the precautions for storing and transporting 1-fluoro-4-chlorobenzene?
1-Jiang-4-Sea sharks should be careful both when they are hidden and when they are lost. If you hide them, you should first pay attention to the place where they are located. You need to choose a cool, dry and well-ventilated place to prevent them from spoiling. The quality of the sea sharks is easy to break in case of damp and heat, so the place you hide must meet these conditions before they can last for a long time.
Furthermore, you should also pay attention to the utensils you hide. It is better to use porcelain urns or wooden boxes, because they can slow down the change of temperature and humidity and protect the quality of the sea sharks. Do not use rusty iron tools, for fear that rust will stain them and damage their original nature.
As for losing them, it is necessary to have a stable path. The chariots and horses that are transported are selected to be solid and stable, in order to prevent the sea sharks from being damaged due to turbulence. And during the journey, you need to check when you need to check, and if the road conditions are not good, you should be more cautious and slow.
Also, pay attention to the season of losing. It is advisable to avoid the days of extreme heat and cold. In the heat, the sea sharks are perishable, and in the severe cold, they are afraid of freezing. In spring and autumn, the climate is mild, which is a good time to lose.
In addition, everyone who loses should be aware of their physical properties and handle them with caution. Do not treat them rudely, or cause them to be injured. All these are things that should be paid attention to by the Tibetan and the sea sharks, and must not be ignored, so as to keep the sea sharks intact and