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1-Fluoro-3-(Trifluoromethoxy)Benzene

1-Fluoro-3-(Trifluoromethoxy)Benzene

Hongda Chemical

Specifications

HS Code

632496

Chemical Formula C7H4F4O
Molecular Weight 182.1
Appearance Colorless liquid
Boiling Point 118 - 120 °C
Melting Point N/A
Density 1.32 g/cm³
Flash Point 25 °C
Solubility In Water Insoluble
Vapor Pressure N/A
Refractive Index 1.388 - 1.392
Odor Characteristic aromatic odor

As an accredited 1-Fluoro-3-(Trifluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - fluoro - 3 - (trifluoromethoxy)benzene in 500 mL glass bottle packaging.
Storage 1 - Fluoro - 3 - (trifluoromethoxy)benzene should be stored in a cool, well - ventilated area, away from heat sources and open flames as it is likely flammable. Keep it in a tightly closed container, preferably made of materials resistant to chemical corrosion. Store it separately from oxidizing agents and reactive substances to prevent potential chemical reactions.
Shipping 1 - fluoro - 3 - (trifluoromethoxy)benzene is shipped in specialized, well - sealed containers. These containers are designed to prevent leakage and withstand transportation conditions, ensuring safe delivery of this chemical.
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1-Fluoro-3-(Trifluoromethoxy)Benzene 1-Fluoro-3-(Trifluoromethoxy)Benzene
General Information
Historical Development
Scholars who have heard of ancient times, every time they study the beginning and end of a thing, they must study its source and explore its rheology. Today, there is 1-Fluoro-3- (Trifluoromethoxy) Benzene, which began to appear in the academic world and has undergone changes over time.
At the beginning, many researchers occasionally got clues about this compound in various experiments. At that time, the technology was not refined, and the cognition was still shallow, and only a few or two of its characteristics were known. However, they were eager to learn, and everyone worked tirelessly to study it.
With the passage of time and the advancement of technology, the understanding of 1-Fluoro-3- (Trifluoromethoxy) Benzene is gradually deepening. From structural analysis to property exploration, step by step. Its application field has also gradually expanded, emerging in medicine and materials.
Looking at its development, it is like a stream converging on a river, starting from the end of the micro and gradually becoming a big view. Although the road of exploration in the past was full of thorns, with the perseverance of scholars, the mystery of this thing was gradually clarified, and it was used by future generations.
Product Overview
1 - Fluoro - 3 - (Trifluoromethoxy) Benzene is a unique compound in the field of organic chemistry. In its structure, the fluorine atom is cleverly connected to the trifluoromethoxy group on the benzene ring, giving this compound special physical and chemical properties.
In terms of appearance, it is usually a colorless and transparent liquid with certain volatility. Its physical properties, such as boiling point and melting point, are specific due to the unique substituents, and the boiling point is about a specific temperature range. This is due to the intermolecular force being affected by fluorine and trifluoromethoxy.
Chemically, the electron cloud density of the benzene ring changes due to the presence of fluorine and trifluoromethoxy, which makes it exhibit different activities in many chemical reactions such as electrophilic substitution reactions. In the field of organic synthesis, it is often used as a key intermediate to participate in the preparation of various complex organic compounds. It can be skillfully combined with other reagents through specific chemical reaction paths to build more complex organic structures, which have potential application value in many fields such as medicine and materials.
Physical & Chemical Properties
1 - Fluoro - 3 - (Trifluoromethoxy) Benzene is a unique compound. Its physical and chemical properties are unique and have attracted much attention in the field of scientific research.
Looking at its physical properties, under normal temperature and pressure, this substance is mostly liquid, with a clear color and a specific odor. Its boiling point and melting point are also characteristic, with a boiling point of about [X] ° C and a melting point of about [X] ° C. The values of this boiling point and melting point make it exhibit a unique phase change in a specific temperature range, which limits its storage and use conditions.
When it comes to chemical properties, 1 - Fluoro - 3 - (Trifluoromethoxy) Benzene has a certain chemical activity. Because it contains fluorine and trifluoromethoxy functional groups, it can be used as a unique reaction check point in many chemical reactions, participating in nucleophilic substitution, electrophilic substitution and other reactions, providing rich possibilities for organic synthetic chemistry, and may have potential applications in pharmaceutical chemistry, materials science and other fields.
Technical Specifications & Labeling
1 - Fluoro - 3 - (Trifluoromethoxy) Benzene is a unique chemical product. Its technical specifications and identification (product parameters) are crucial.
When it comes to technical specifications, this product needs to meet specific purity standards, and the impurity content must be strictly controlled at a very low level to ensure high quality. And its physical properties, such as color, state, melting point, boiling point, etc., should conform to the established specifications.
As for the logo, clearly label the product name, chemical formula, that is, 1 - Fluoro - 3 - (Trifluoromethoxy) Benzene, and key product parameters, such as purity values, hazard warnings, etc. In this way, users can clarify their characteristics and precautions for use, ensure safe operation and proper use of the product, and play its due role in the chemical industry.
Preparation Method
1 - Fluoro - 3 - (Trifluoromethoxy) Benzene is an important organic compound, and the preparation method is crucial.
The selection of raw materials is very critical, and the fluorine-containing and methoxy-containing compounds are used as the starting point. The first step of the preparation process can be the reaction of a specific halogenated aromatic hydrocarbon with a fluorine-containing reagent under suitable conditions to form a fluorine-containing intermediate. Then, the intermediate is further reacted with the reagent containing trifluoromethoxy to obtain the target product.
The control of the reaction conditions is extremely important, and the temperature, pressure, and catalyst dosage will all affect the reaction process. If the temperature is too high, or the side reactions will increase; if the temperature is too low, the reaction rate will slow down. The catalyst used can effectively improve the reaction activity and selectivity.
In addition, the separation and purification steps are also indispensable. Distillation, extraction, recrystallization and other means are used to obtain high-purity 1-Fluoro-3- (Trifluoromethoxy) Benzene to ensure product quality.
Chemical Reactions & Modifications
Guanfu 1 - Fluoro - 3 - (Trifluoromethoxy) Benzene is the key to reaction and modification in the field of chemical synthesis.
To prepare this product, a specific raw material is often used, according to a certain reaction path. However, the initial reaction may be unsatisfactory, the yield is not ideal, and impurities may also exist.
Therefore, all chemists work hard and think about changes. After repeated experiments, the reaction conditions are improved, such as temperature adjustment and catalyst selection. Finally, the efficiency of the reaction can be improved, and the purity of the product can be greatly improved.
This change is not unique to 1 - Fluoro - 3 - (Trifluoromethoxy) Benzene, but also follows this principle in all fields of chemistry. With unremitting exploration, we can strive for the improvement of chemistry, and strive to reach the realm of reaction optimization and physical property improvement. We will contribute our efforts to the prosperity of industry and the benefit of people's livelihood.
Synonyms & Product Names
1 - Fluoro - 3 - (Trifluoromethoxy) Benzene, which is in the field of our chemical research, has unique characteristics and uses. Its synonyms and trade names are also important to us.
I have heard the ancients say: "If the name is not correct, it will not go well." In the realm of chemistry, the accuracy of the name is related to the accuracy of the research. 1 - Fluoro - 3 - (Trifluoromethoxy) Benzene is a synonym, either according to its structural characteristics or according to its synthesis method. The trade name involves the regulations of merchants and the needs of the market.
This compound has a delicate structure and contains fluorine and trifluoromethoxy groups, which gives it special physical and chemical properties. In the process of organic synthesis, it is often a key raw material and can be used to produce a variety of high-value-added products. Its synonyms and trade names are used in academia and industry, and are a bridge of communication. We must understand its various titles when we study them, so that we can travel freely in the ocean of chemical knowledge, explore its endless secrets, and exhaust our wisdom for the advancement of science and industry.
Safety & Operational Standards
1 - Fluoro - 3 - (Trifluoromethoxy) Benzene Safety and Operation Specifications
F 1 - Fluoro - 3 - (Trifluoromethoxy) Benzene, chemical products are also used. Its safe operation is very important and cannot be ignored.
#1. The method of storage
should be placed in a room where it is difficult to operate. Fire, source, should not exceed 30 ℃. Oxidation, acid, aliquot storage, do not mix. There are leaks Emergency treatment and Container materials.
#2. The operation requires
Close operation, add pass. The operator must be trained and trained, and must abide by the operation procedures. The operator must wear a self-priming gas mask (half mask), wear a safety and anti-eye mask, wear anti-poison overalls, and wear rubber and oil-resistant gloves. Fire source, No suction in the work area. Use explosion-proof pass-through systems and sensors. Prevent steam leakage into the work area. Avoid oxidation, acid, If the eyes are connected, immediately lift the eyes and wash them with a large amount of flowing water or physiological water for at least 15 minutes. If inhaled, quickly reach the air and keep the respiratory tract open, such as respiratory distress, oxygen, if the breathing stops, immediately perform artificial respiration, then. If you eat enough water to induce vomiting, then.
As a result, for the use and storage of 1-Fluoro-3- (Trifluoromethoxy) Benzene, follow this safe operation to ensure safety.
Application Area
1 - Fluoro - 3 - (Trifluoromethoxy) Benzene is a special chemical substance. It has a wide range of uses in many application fields. In the field of medicinal chemistry, this compound can be used as a key intermediate to assist in the synthesis of drug molecules with specific biological activities. Due to its unique chemical structure, it can bring unique pharmacological properties to drugs.
In the field of materials science, 1 - Fluoro - 3 - (Trifluoromethoxy) Benzene can participate in the preparation of high-performance materials. Its fluorine content can enhance the stability, corrosion resistance and weather resistance of materials, thereby improving material properties.
In the field of organic synthesis, this substance can be used as a reaction substrate to derive organic compounds with different structures through various chemical reactions, expanding the diversity of organic synthesis. All of these highlight the important value of 1 - Fluoro - 3 - (Trifluoromethoxy) Benzene in many application fields.
Research & Development
In recent years, I have been in the field of chemistry, specializing in the study of 1 - Fluoro - 3 - (Trifluoromethoxy) Benzene. Its unique properties, in various reactions, quite specific effects.
At the beginning, the study of its synthesis method has gone through many twists and turns. The choice of raw materials and the degree of matching all need to be carefully considered. After several attempts, a feasible way has been obtained, and the yield has gradually improved.
Then, explore its application in different scenarios. In the synthesis of medicine, it can assist in the construction of active molecules, or it can become the basis of new drugs; in the preparation of materials, add its special properties, and hope to expand the new field of materials.
I am well aware that the road of science is long, and this is just the beginning. In the future, we will continue to study, optimize the synthesis, and explore the application of this material. We hope to use this material as a reference to promote progress in the field of chemistry. In the process of research and development, we will continue to explore and reach new frontiers.
Toxicity Research
The difference between taste and smell of physical properties is related to the safety of people's livelihood. Now look at 1 - Fluoro - 3 - (Trifluoromethoxy) Benzene, the study of its toxicity is quite important.
This thing is also, although it is not widely used in Lu Yan, it has traces in the field of chemical industry from time to time. To explore its toxicity, we need to use scientific methods to observe its relationship with things and people.
Observe the structure of its molecules, the genus of fluorine and trifluoromethoxy, or endow it with unique properties. In animal tests, observe the changes and physiological differences in organs after ingestion. If it involves the skin, observe whether it is sensitized or damaged.
And its volatile qi enters the lungs, what do you feel? Or cause diseases of the airway, or disturb the flow of qi and blood.
The study of toxicity cannot be ignored. It is necessary to carefully examine the change of its concentration and the length of contact before we can find out the truth. We hope to be cautious and investigate its toxicity, so as to avoid harm and profit for the world, and protect ourselves on the road to health.
Future Prospects
Fu 1 - Fluoro - 3 - (Trifluoromethoxy) Benzene is also a thing of transformation. Its future prospects can be looked forward to. In the field of engineering, or it can be the research of new materials, and it will be a new way. With its unique transformation, it may be as effective as ever, helping to synthesize new frontiers.
In the field of engineering, there are also encounters. Or it can be repaired, combined, and the new building blocks can be created to create diseases. And in terms of sub-materials, its characteristics may add help and promote the development of sub-technologies.
Well, 1 - Fluoro - 3 - (Trifluoromethoxy) Benzene is not yet ready, just like jade to be cut, and it is possible. If it is carefully researched in a long time, it will definitely be able to greatly expand the color and benefit many fields.
Where to Buy 1-Fluoro-3-(Trifluoromethoxy)Benzene in China?
As a trusted 1-Fluoro-3-(Trifluoromethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-3-(Trifluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-fluoro-3- (trifluoromethoxy) benzene?
The main uses of 1-% water-3- (trimethoxy) silicon are as follows:
This substance is used in the construction field and is mostly used as a waterproof agent. It can generate a tight and long-lasting hydrophobic film on the surface of building materials, which can effectively resist the intrusion of rain and moisture, thereby significantly improving the waterproof performance and durability of buildings. Taking the repair of ancient city walls as an example, applying a waterproof agent containing this ingredient on the surface of masonry can prevent the weathering and peeling of the wall due to water erosion for a long time, so that the city wall can be preserved for a long time.
In the textile industry, it is often used as a fabric finishing agent. The fabric treated by it not only has good water repellency, but also maintains the original air permeability and softness. After similar treatment, silk fabrics in ancient times were waterproof without losing their delicate texture, and could better resist moisture damage during transportation and storage.
In the paint industry, it is an important additive. Adding this substance can enhance the adhesion between the paint and the base material, and improve the wear resistance, corrosion resistance and weather resistance of the coating. If similar ingredients are added to ancient painting pigments, the color of the painting can remain bright over the years, and it is not easy to fade or peel off.
In the electronics industry, it can be used for moisture-proof and insulation treatment of electronic components. It can create a stable internal environment for electronic equipment and ensure its normal operation under different humidity conditions. Like ancient precision machinery, after similar moisture-proof treatment, parts corrosion and performance damage caused by moisture can be avoided.
In summary, 1-% water-3- (trimethoxy) silicon plays a key role in many fields due to its waterproof, protective, and enhanced properties, helping various materials and items improve performance and prolong service life.
What are the physical properties of 1-fluoro-3- (trifluoromethoxy) benzene?
1-% -3- (trimethoxy) naphthalene is an organic compound with unique physical properties. It is solid at room temperature and has a melting point within a certain range. The specific value varies depending on factors such as purity, usually between several degrees Celsius. This property allows it to maintain a solid state under specific temperature conditions, which affects its processing and application methods in material preparation, chemical process, etc.
The boiling point of this substance is also a key physical property. When it reaches a certain temperature, it will boil and transform into a gaseous state. This temperature is also affected by various factors, providing a key reference for the separation and purification of this substance in chemical operations.
In terms of solubility of 1-% -3- (trimethoxy) naphthalene, it has a certain solubility in organic solvents such as common ethanol, ether, etc., but it is difficult to dissolve in water. This property is of great significance in the extraction, separation and solution preparation of substances. According to its solubility differences, suitable solvents can be selected to achieve effective treatment and utilization of it.
In addition, the density of the compound is also a specific value, reflecting the quality of the unit volume, which is very important in chemical production processes such as material measurement and mixing ratio. It is important to ensure the accurate ratio of each ingredient and ensure product quality and reaction effect. It may also have specific optical properties, or it may have absorption or emission characteristics for specific wavelengths of light, and may have potential applications in optical materials, analytical testing, and other fields.
Is 1-fluoro-3- (trifluoromethoxy) benzene chemically stable?
1-%E6%B0%9F-3-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E6%B0%A7%E5%9F%BA%29%E8%8B%AF, the stability of its chemical properties is really related to multiple reasons.
Looking at its structure, this compound has a specific atomic arrangement and chemical bonding. The interaction of the groups it contains has a great impact on its stability. Just like building a castle, the connection of each part is stable, and the whole is firm. The atoms in this compound are supported by a specific force. If the external force is not enough to break the force of this maintenance, its structure is stable and its properties are not easy to change.
In terms of its environment, temperature, humidity, light, etc. are all key. When the temperature rises, the molecular motion intensifies. If a certain threshold is reached, the molecular energy is enough to break its original chemical bond, causing its structure to change and its properties to be unstable. Just like putting a solid wood in a hot fire, under high temperature, the quality of the wood will be changed. The same is true for humidity. In a high humidity environment, moisture may participate in chemical reactions or affect its surface properties, which in turn affects its stability. Light also plays a role. Light of a specific frequency can provide energy, stimulate electron transitions in molecules, cause chemical reactions, and shake its stability.
Then explore the way of preparation and preservation. If the preparation process is improper, or impurities remain, it can affect its stability. Impurities or defects in a pavilion, although small, can cause overall instability. When stored, if the appropriate container and conditions are not selected according to its characteristics, it is easy to deteriorate.
However, its stability cannot be generalized. In the conventional environment and conditions, if the structure is reasonable, well prepared and properly preserved, the 1-%E6%B0%9F-3-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E6%B0%A7%E5%9F%BA%29%E8%8B%AF may have considerable stability. However, in the case of extreme conditions, such as strong acid and alkali erosion, hot topic high pressure environment, its stability may be difficult to maintain. It is necessary to observe its stability under different conditions according to its specific application scenarios and needs in order to make good use of it.
What are the preparation methods of 1-fluoro-3- (trifluoromethoxy) benzene?
To prepare 1-alkane-3- (trimethoxy) benzene, the method is as follows:
First take the appropriate starting material, if you want to prepare 1-methyl-3- (trimethoxy) benzene, you can choose m-methylphenol as the starting material. React m-methylphenol with suitable halogenated alkanes, such as iodomethane, in an alkaline environment. The base can be selected from potassium carbonate, etc., in an organic solvent such as N, N-dimethylformamide (DMF), heat and stir, and the methoxylated product can be obtained in this step. The mechanism of this reaction is a nucleophilic substitution reaction. The oxygen atom of the phenolic hydroxyl group is nucleophilic, and the carbon atom of the halogenated alkane is partially positively charged. The two interact, and the halogen ions leave to form methoxylation products.
Then, if you need to introduce other alkyl moieties in the trialkyl methoxy group, you can select the corresponding halogenated hydrocarbon according to your specific needs. If you want to introduce ethyl group, you can choose bromoethane. The product obtained in the previous step is reacted with the selected halogenated hydrocarbon in the presence of a basic and phase transfer catalyst under specific conditions. The phase transfer catalyst can be selected from tetrabutylammonium bromide, etc. The base can still be used in potassium carbonate or the like, and the reaction can be heated in a suitable organic solvent This step is also a nucleophilic substitution reaction. After this step, the target product 1-alkane-3- (trimethoxy) benzene can be obtained.
When operating, pay attention to the reaction temperature, the proportion of reactants and the reaction time. If the temperature is too high, it may increase side reactions, such as the elimination reaction of halogenated hydrocarbons; if the proportion of reactants is improper, the raw materials may remain and the yield of the product will be reduced. The reaction time also needs to be strictly controlled. If it is too short, the reaction will not be completed, and if it is too long, other side reactions may occur. And after each step of the reaction, appropriate separation and purification methods, such as extraction and column chromatography, are required to obtain a pure product. In this way, the target 1-alkane-3-trimethoxy benzene can be obtained.
What is the price range of 1-fluoro-3- (trifluoromethoxy) benzene in the market?
The price range of 1-% He-3- (triethoxy) silicon in the market is difficult to determine. The price of this silicide often changes for various reasons.
First, it is related to quality and purity. If the quality is excellent and the purity is high, the price will inevitably increase; if it contains a lot of heterogeneity and the quality is uneven, the price may drop.
Second, the supply and demand of the market determine the price. There are many people who want it, but the supply is small, and the price will rise; if the supply exceeds the demand, the price will often go down.
Third, the cost of production is also the main reason. The price of raw materials, the difficulty of work, and the amount of energy consumption are all costs. If the cost is high, the selling price will be difficult to lower; if the cost is reduced, the price may be compromised.
Fourth, the origin and the transportation route also have an impact. If the product is close to the city, the transportation fee will be saved, and the price may be close to the people; if the origin is far away, the transportation route will be difficult, and the fee will increase, the price will rise.
To sum up, if you want to know the exact price of 1-% river-3- (triethoxy) silicon, you can get a near-real price when you study the market conditions at the time, consult the supplier, and observe the business conditions. Or at some point, the price is between tens of dollars and hundreds of dollars per catty, but this is only an approximate number, not an exact value.