Hongda Chemical
Products
Home  /  Products  / 

1-Fluoro-3-Nitrobenzene

1-Fluoro-3-Nitrobenzene

Hongda Chemical

Specifications

HS Code

606947

Chemical Formula C6H4FNO2
Molecular Weight 141.1
Appearance Colorless to light yellow liquid
Boiling Point 187 - 188 °C
Melting Point -16 °C
Density 1.325 g/cm³
Flash Point 74 °C
Solubility In Water Insoluble
Vapor Pressure 0.24 mmHg (25 °C)
Refractive Index 1.521

As an accredited 1-Fluoro-3-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - fluoro - 3 - nitrobenzene packaged in 500 - gram bottles for chemical use.
Storage 1 - fluoro - 3 - nitrobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. It should be stored in a tightly - sealed container to prevent vapor leakage. Keep it separate from oxidizing agents, reducing agents, and reactive metals. Store in a dedicated chemical storage area following local safety regulations.
Shipping 1 - fluoro - 3 - nitrobenzene is shipped in tightly - sealed, corrosion - resistant containers. It's transported by specialized chemical carriers, ensuring compliance with safety regulations to prevent leakage and maintain product integrity during transit.
Free Quote

Competitive 1-Fluoro-3-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

1-Fluoro-3-Nitrobenzene 1-Fluoro-3-Nitrobenzene
General Information
Historical Development
1 - Fluoro - 3 - Nitrobenzene is an important chemical product. Its historical development contains many explorations from the past. The former chemist, who studied the properties of matter, gradually observed the uniqueness of this compound. At the beginning, the understanding was still shallow, and only a little bit of its characterization was known. However, with the passage of time, the research deepened. Various experiments were carried out one after another to clarify its structure, properties and synthesis methods. At that time, the synthesis technique was still simple, and the yield was also low. However, the ambition of chemists did not decrease, and they were determined to improve. After countless attempts, better synthesis paths were gradually found, and the yield was improved. Up to now, the application of 1 - Fluoro - 3 - Nitrobenzene has been widely involved in many fields, which is the result of the unremitting exploration of chemists through the ages.
Product Overview
1 - Fluoro - 3 - Nitrobenzene is an organic compound. It is a colorless to light yellow liquid with a special odor. In this compound, fluorine atoms and nitro groups are attached to the benzene ring, and the structure is unique.
The preparation method often starts with benzene and is obtained by several steps of nitrification and halogenation. During nitrification, nitro groups are introduced; after halogenation, fluorine atoms are added to the benzene ring. This preparation process requires controlling the reaction conditions, such as temperature and the ratio of reagents, to achieve a higher yield.
1 - Fluoro - 3 - Nitrobenzene is widely used in the field of organic synthesis. It can be used as an intermediate to prepare other fluorine-containing organic compounds, or to play a key role in the research and development of medicines and pesticides. Because of its structural properties, it can endow new compounds with specific biological activities and chemical properties, so it is important in the chemical industry.
Physical & Chemical Properties
1 - Fluoro - 3 - Nitrobenzene is an organic compound. It has unique physical and chemical properties. Looking at its physical properties, it is a colorless to light yellow liquid at room temperature, has a special odor, has a higher density than water, is difficult to dissolve in water, but is easily soluble in organic solvents such as ethanol, ether, etc. As for chemical properties, the presence of fluorine atoms and nitro groups makes it have certain reactivity. Nitro is a strong electron-absorbing group, which reduces the electron cloud density of the benzene ring and weakens the electrophilic substitution reactivity; although fluorine atoms are electron-absorbing groups, their effect on ortho-para-location is significant. This compound is widely used in the field of organic synthesis. It can be used as an intermediate to participate in a variety of organic reactions, and to synthesize fine chemicals such as drugs and dyes. It is an important raw material for chemical research and industrial production, and is of great significance for promoting the development of organic chemistry.
Technical Specifications & Labeling
1 - Fluoro - 3 - Nitrobenzene, chemical products are also. Its process specifications and identification (commodity parameters) are very important. Looking at this product, it is necessary to clarify its properties, and it is better to have a uniform color and quality. Its fluorine and nitro content, when it meets the standard of precision, can not exceed the moment. On the logo, the name is clear, the molecular formula and molecular weight are conclusive, and there are warning words, indicating that its nature is dangerous, such as flammable and toxic. The production process, the raw materials must be well selected, the reaction temperature, pressure and time are fixed, and the catalytic agent must also be appropriate. After multiple processes, fine filtration and purification, the best product can be obtained. The inspection of the finished product is in accordance with strict regulations, and those who do not comply will not be allowed to enter the market. In this way, the quality of 1-Fluoro-3-Nitrobenzene is guaranteed to meet the needs of all parties.
Preparation Method
1 - Fluoro - 3 - Nitrobenzene is an important organic compound. The preparation method, raw materials and production process, reaction steps and catalytic mechanism are all key.
To prepare this compound, the common raw materials are m-nitrochlorobenzene and potassium fluoride. First, m-nitrochlorobenzene and potassium fluoride are placed in a specific organic solvent, which needs to be able to dissolve both and have stable properties. Heating to a suitable temperature is a key step in the reaction. During the heating process, the fluoride ion of potassium fluoride undergoes a substitution reaction with the chlorine atom of m-nitrochlorobenzene, which is the core of the reaction step.
In order to speed up the reaction rate and increase the yield, a phase transfer catalyst is often added, which is an important part of the catalytic mechanism. The phase transfer catalyst can promote the efficient reaction between different phases, and accelerate the reaction of the originally slow system. After a series of reactions, after separation and purification, pure 1-Fluoro-3-Nitrobenzene can be obtained. In this way, high-quality products can be prepared.
Chemical Reactions & Modifications
1 - Fluoro - 3 - Nitrobenzene is an important compound in organic synthesis. Its chemical properties are crucial in chemical reactions.
In terms of its chemical reaction, the presence of fluorine atoms and nitro groups gives this compound a unique activity. Fluorine atoms have high electronegativity, which affects the distribution of electron clouds in the benzene ring and reduces the density of electron clouds in the benzene ring. Nitro groups are also electron-absorbing groups, and the two work together to change the activity of the electrophilic substitution reaction of the benzene ring.
If you want to improve its chemical activity, the reaction conditions can be carefully adjusted. For example, changing the reaction temperature and selecting a suitable catalyst may promote the reaction to progress in the desired direction. Increasing the temperature can usually speed up the reaction rate; and suitable catalysts can reduce the activation energy of the reaction and greatly improve the reaction efficiency. Through these means, the chemical reactions involved in 1-Fluoro-3-Nitrobenzene can be optimized to improve the production efficiency and purity of the product.
Synonyms & Product Names
1 - Fluoro - 3 - Nitrobenzene is also a chemical product. Its same product name is exquisite. The same product name may be different due to differences in cost and region. Merchants recognize their own characteristics, each with their own ingenuity.
Husband 1 - Fluoro - 3 - Nitrobenzene, in the field of chemistry, the use is not the same. Or raw materials for synthesizing polymers and refined products. Due to its characteristics, it is sensitive to anti-sensitivity, which can lead to the transformation of polymers.
Its same product, or fluoronitrobenzene, is named according to its functional position. In empty words, fluoronitro is located in the benzene position, hence the name. The name of the product depends on the home, but it all indicates the characteristics of its product and use. For example, the "refined fluoronitrobenzene" of a certain product is intended to demonstrate its high degree of accuracy and outstanding effectiveness in chemical synthesis. All this is to make this product in the market and the world, and each has its own place. It is a combination of research, engineering and production, and adding extra watts.
Safety & Operational Standards
1 - Fluoro - 3 - Nitrobenzene is a chemical substance. It is crucial for its safety and operating practices. It is described in detail below.
In terms of storage, be sure to choose a cool, dry and well-ventilated place. This product is dangerous to a certain extent. If the storage environment is not good, it may cause accidents. Keep away from fire and heat sources. Needless to say, because it encounters open flames, hot topics, or the risk of combustion and explosion. It should be stored separately from oxidizing agents, reducing agents, alkalis, etc., and must not be mixed. Because of its active chemical properties, contact with the above substances, or react violently.
When operating, the operator must undergo special training and strictly abide by the operating procedures. It is recommended that operators wear self-priming filter gas masks (half masks), chemical safety protective glasses, anti-poison penetration work clothes, and rubber oil-resistant gloves to ensure their own safety. Operating places should be kept away from fire and heat sources, and smoking is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment to prevent steam from leaking into the air of the workplace. Avoid contact with oxidants, reducing agents, and alkalis. When handling, it should be lightly loaded and unloaded to prevent damage to packaging and containers. Equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. Emptied containers may have residual harmful substances and should not be taken lightly.
In the event of a leak, quickly evacuate personnel from the leak-contaminated area to a safe area, and isolate them, strictly restricting access. Cut off fire sources. It is recommended that emergency personnel wear self-contained positive pressure respirators and anti-toxic clothing. Do not come into direct contact with leaks. Cut off the source of leaks as much as possible. Prevent flowing into restricted spaces such as sewers and flood ditches. Small leaks: adsorb or absorb with sand or other non-combustible materials. It can also be scrubbed with emulsions made of non-combustible dispersants, and the lotion is diluted and placed into the wastewater system. Large leaks: build embankments or dig pits for containment. Cover with foam to reduce vapor disasters. Transfer to a tanker or special collector with a pump, recycle or transport to a waste treatment site for disposal.
In short, the safe and standardized operation of 1-Fluoro-3-Nitrobenzene is related to the safety of personnel and the environment. It must not be ignored or careless.
Application Area
1 - Fluoro - 3 - Nitrobenzene is an organic compound with a wide range of application fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate. If you want to make some drugs with specific therapeutic effects, this compound can introduce specific functional groups through a series of reactions to obtain molecular structures with precise pharmacological activity, which can help treat diseases.
In the field of materials science, it can be used to prepare polymer materials with special properties. By polymerizing with other monomers, it gives materials unique electrical, optical or mechanical properties, suitable for various scenarios such as electronics and optical instruments.
In the fine chemical industry, it is also an important raw material. It can synthesize high-value-added fine chemicals, such as special dyes, fragrances, etc., to improve product quality and performance and meet market demand for high-end fine chemical products.
Research & Development
In recent years, I have focused on the investigation of 1-Fluoro-3-Nitrobenzene in chemical analysis. This substance has unique properties and has potential applications in various fields of chemical industry.
At the beginning, I studied its synthesis method. After repeated experiments, various reaction conditions, such as temperature, pressure, and catalyst genus, were carefully observed. Strive to find an efficient and pure synthesis path. During this time, the reaction yield was not as expected, and the impurities were difficult to remove. However, I did not give up, but studied the cause of the failure and adjusted the plan. Finally, a method was obtained, which can significantly improve the yield and purity.
Then, explore its properties. Observe its physical properties to illustrate its chemical activity. This substance can undergo various reactions under specific conditions, paving the way for subsequent applications. Today, although it has achieved success, it is well aware that there is a long way to go. In the future, it is hoped that this research result will be extended to make it effective in industrial production, scientific research and exploration, etc., to promote the development of the chemical field.
Toxicity Research
The rise of modern chemistry has a variety of categories, exploring physical properties, and affecting people's livelihood. Today, there is 1-Fluoro-3-Nitrobenzene, and toxicity research is particularly important.
Looking at its molecular structure, fluorine is connected to nitro groups, which is lively in nature and may have potential harm. In the experiment, a white rat was used as a test and placed in this environment. Not long after, the white rat was slow to move and looked sluggish, showing signs of toxicity.
And if this substance is dispersed in the air, it can be inhaled by humans, or it may hurt the respiratory system, causing cough and asthma. If it enters the water body, aquatic things are also damaged, and the ecological balance is at risk.
We chemical researchers should be very careful to explore the root cause of its toxicity, find protective measures, and formulate rules for use, so as to prevent its harm from flowing into the world, protect the well-being of all people, and protect the peace of heaven and earth.
Future Prospects
1 - Fluoro - 3 - Nitrobenzene is also a new chemical product that I am researching today. To observe this product, its characteristics are specific, and it lurks in various fields of chemical industry.
Although the research is not deep now, my heart looks forward to the future, and the prospect is clear. With time and intensive study of its properties, it will be able to expand its use. Or it can be used to create new agents, increase the effect of medicine, and save people from diseases and pains; or it can help to make new materials, make utensils strong and beautiful, and be widely used in various industries.
Thinking about the method of synthesis, we should strive to improve, reduce its consumption, and improve its production, so as to achieve this good product with efficient methods. I believe that with time, 1 - Fluoro - 3 - Nitrobenzene will be able to achieve its success and make 1 - Fluoro - 3 - Nitrobenzene shine in the future, making great contributions to the prosperity of the chemical industry and the people's livelihood.
Where to Buy 1-Fluoro-3-Nitrobenzene in China?
As a trusted 1-Fluoro-3-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-3-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Fluoro-3-Nitrobenzene?
1-Fluoro-3-nitrobenzene is an important chemical substance in the field of organic synthesis. It has a wide range of main uses and plays a key role in many chemical processes.
First, in the synthesis of medicine, this compound is often a key intermediate. Due to the characteristics of fluorine atoms and nitro groups in its structure, it can participate in a variety of chemical reactions to build complex molecular structures with specific physiological activities. For example, through appropriate reaction steps, it can be converted into drug molecules for the treatment of specific diseases, contributing a lot to human health and well-being.
Second, in the field of pesticide creation, 1-fluoro-3-nitrobenzene also plays an important role. Through its participation in synthetic reactions, pesticide products with high insecticidal, bactericidal or herbicidal effects can be prepared. The introduction of fluorine atoms can often enhance the stability and biological activity of pesticide molecules, while nitro groups can affect their mechanism of action, making pesticides play an important role in protecting crop growth and resisting pest attacks.
Furthermore, in the field of materials science, it also has applications. By reacting with other compounds, materials with special properties can be prepared. For example, some polymer materials containing fluorine and nitro groups, or have unique electrical, optical or mechanical properties, can be applied to electronic devices, optical instruments and many other aspects to promote the progress and development of materials science.
In conclusion, the unique chemical structure of 1-fluoro-3-nitrobenzene has shown important uses in many fields such as medicine, pesticides and materials, providing indispensable assistance for the development of various fields.
What are the physical properties of 1-Fluoro-3-Nitrobenzene?
1-Fluoro-3-nitrobenzene is also an organic compound. It has various physical properties, which are described in detail below.
First properties, under normal temperature and pressure, 1-fluoro-3-nitrobenzene is colorless to light yellow liquid. It looks clear and has a slightly specific smell. Although this smell is not strong and pungent, it is also unique and can be identified.
Second, its boiling point is between 205 and 207 degrees Celsius. The boiling point is the critical temperature at which a substance changes from liquid to gaseous. At this temperature, the 1-fluoro-3-nitrobenzene molecule is energized enough to break free from the liquid phase and escape into the gas phase.
Furthermore, the melting point is about -27 degrees Celsius. The melting point is the temperature limit at which a substance changes from a solid state to a liquid state. Below this temperature, 1-fluoro-3-nitrobenzene condenses into a solid state, and its molecules are arranged in an orderly manner; above this temperature, it gradually melts into a liquid state, and the molecular motion intensifies.
Its density is about 1.43 g/cm ³. In density, the mass per unit volume of the substance is also. 1-fluoro-3-nitrobenzene has a higher density than water, so if mixed with water, it will sink underwater.
In terms of solubility, 1-fluoro-3-nitrobenzene is insoluble in water, but soluble in many organic solvents, such as ethanol, ether, acetone, etc. This is because water is a polar solvent, while the polarity of 1-fluoro-3-nitrobenzene molecules is weak. According to the principle of "similar miscibility", it is repellent with polar solvent water and miscible with non-polar or weakly polar organic solvents.
In addition, the vapor pressure of 1-fluoro-3-nitrobenzene is lower at room temperature. The vapor pressure is related to the difficulty of volatilization of substances. If the vapor pressure is low, the volatilization is slow, and the diffusion in the air is also slow.
In summary, the physical properties of 1-fluoro-3-nitrobenzene, such as their properties, melting point, density, solubility, vapor pressure, etc., are all important factors to consider in the fields of chemical industry and scientific research, and are related to their storage, transportation, and application.
What is the chemistry of 1-Fluoro-3-Nitrobenzene?
1-Fluoro-3-nitrobenzene is also an organic compound. It has unique chemical properties and is very important in the field of organic synthesis.
First of all, its fluorine atom, fluorine, is an element with strong electronegativity. In 1-fluoro-3-nitrobenzene, fluorine atoms have strong electron-absorbing properties, resulting in a decrease in the electron cloud density of the benzene ring. This property decreases the activity of the electrophilic substitution reaction of the benzene ring, but also affects the distribution of adjacent and para-potential electron clouds, resulting in different reaction check points.
Furthermore, nitro, nitro is also a strong electron-absorbing group. In 1-fluoro-3-nitrobenzene, the synergistic effect of nitro and fluorine atoms makes the electron cloud of the benzene ring more biased towards the two, greatly changing the reactivity of the benzene ring. Nitro can make the electrophilic substitution of the benzene ring more difficult to occur, and guide the nucleophilic reagents to attack the specific position of the benzene ring.
1-fluoro-3-nitrobenzene In the nucleophilic substitution reaction, the fluorine atom can be replaced by other nucleophilic reagents. The fluorine atom is affected by the conjugation effect of nitro and benzene rings, and the carbon-fluorine bond electron cloud is biased towards fluorine, making the carbon atom partially
In the reduction reaction, the nitro group can be reduced to different functional groups such as amino groups, and then a variety of nitrogen-containing derivatives can be prepared, which are widely used in medicine, pesticides and material synthesis.
The chemical properties of 1-fluoro-3-nitrobenzene are determined by the properties of fluorine atoms and nitro groups and their interaction on the benzene ring. It has a wide range of uses in the field of organic synthesis and can be used through various reaction paths to prepare many valuable organic compounds.
What are 1-Fluoro-3-Nitrobenzene synthesis methods?
There are several common methods for the synthesis of 1-fluoro-3-nitrobenzene.
First, m-nitroaniline is used as the starting material. First, m-nitroaniline is reacted with hydrofluoric acid and sodium nitrite, which is a diazotization reaction. The amino group in m-nitroaniline is converted into a diazonium salt by diazotization, and then the diazonium salt forms m-nitrobenzene diazofluoroborate in the presence of fluoroborate ions. This salt is decomposed by heating to obtain 1-fluoro-3-nitrobenzene. The steps of this method are relatively clear, and the diazotization reaction conditions are relatively easy to control. However, it is necessary to pay attention to the safety of the use of sodium nitrite, and the stability of the diazonium salt is slightly less, so the operation needs
Second, m-nitrochlorobenzene is used as raw material. In the presence of specific catalysts such as copper salts, m-nitrochlorobenzene undergoes a halogen exchange reaction with potassium fluoride. In this reaction, chlorine atoms are replaced by fluorine atoms to obtain 1-fluoro-3-nitrobenzene. This approach is relatively easy to obtain raw materials, but the reaction conditions need to be precisely controlled, such as temperature, catalyst dosage, etc., to improve the reaction yield and selectivity.
Third, benzene is used as the starting material. Nitrobenzene is first nitrified to obtain nitrobenzene. Nitrobenzene is then halogenated to selectively introduce fluorine atoms at the meta site. However, there are many steps in this route, and the separation and purification of intermediate products are complicated, and the accumulation of the yield of each step has a great influence on the yield of the final product. In actual synthesis, the most suitable synthesis path should be selected according to various factors such as raw material availability, cost, reaction conditions and yield.
1-Fluoro-3-Nitrobenzene What are the precautions during storage and transportation?
1-Fluoro-3-nitrobenzene is also an organic compound. When storing and transporting, there are several ends that should be added.
First words storage, this substance is dangerous, when stored in a cool and ventilated warehouse. Cover its heat is prone to danger, so the temperature between the warehouses should not be too high. And it must be kept away from fire and heat sources to prevent the risk of explosion caused by heat. And because of its active chemical properties, it should be stored separately from oxidizing agents, reducing agents, alkalis, etc., and must not be mixed to prevent violent chemical reactions. Storage places should be prepared with suitable materials to contain leaks for emergencies.
As for transportation, it is necessary to ensure that the packaging is complete and the loading is safe before transportation. During transportation, the speed of the vehicle should not be too fast, nor should it be braked abruptly to avoid material leakage caused by packaging damage. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. During transportation, it is not allowed to be mixed with contraband materials, and it is necessary to prevent exposure to the sun, rain, and high temperature. When loading and unloading personnel operate, they should also load and unload lightly. It is strictly forbidden to drop and press heavily, so as not to damage the packaging and endanger safety. In short, during the storage and transportation of 1-fluoro-3-nitrobenzene, care must be taken to ensure safety.