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1-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene

1-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    763992

    Chemical Formula C7H3F4NO2
    Molecular Weight 209.098 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point 174 - 176 °C
    Melting Point N/A
    Density 1.514 g/cm³
    Flash Point 74 °C
    Solubility In Water Insoluble
    Vapor Pressure N/A
    Refractive Index 1.452 - 1.454

    As an accredited 1-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 1 - fluoro - 3 - nitro - 5 - (trifluoromethyl)benzene in a sealed, corrosion - resistant bottle.
    Storage 1 - fluoro - 3 - nitro - 5 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air or moisture, which could potentially lead to decomposition or reactivity issues.
    Shipping 1 - fluoro - 3 - nitro - 5 - (trifluoromethyl)benzene is a chemical. Shipping should comply with hazardous materials regulations. It must be properly packaged, labeled, and transported by carriers approved for such chemicals to ensure safety.
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    1-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene 1-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene is also used to transform things. At the beginning, those who transform things study material resources and want to obtain this special thing. The beginning of exploration, the road of exploration is new, and the method of research is not yet available. However, those who work tirelessly will not be tired, and they will work hard. The moon will change, the technology will be better, and the method of research will be better. Or change the original piece, or the raw material that is easy to use. Only then can we take it and make it. Since then, this object has been used in the field of chemistry, and it is the way of research and engineering. Therefore, in the course of its development, those who have made unremitting efforts to research and promote new technologies have also recognized the diligence and wisdom of science and technology.
    Product Overview
    1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene is an organic compound. It may be a colorless liquid with a special odor. This compound contains fluorine, nitro and trifluoromethyl groups and has a unique structure. Its chemical properties are active. Due to the strong electron absorption of nitro groups, the electron cloud density of the benzene ring is reduced, and it is easy to initiate nucleophilic substitution reactions.
    In the field of organic synthesis, it has a wide range of uses. It can be used as a key intermediate to prepare many biologically active compounds, such as pharmaceuticals, pesticides, etc. The preparation method often uses specific benzene derivatives as the starting material and is prepared by a series of reactions such as halogenation, nitrification, and trifluoromethylation.
    When using it, pay attention to its safety. Due to its certain toxicity and irritation, when operating, follow strict safety procedures and work in a well-ventilated environment to prevent harm to personal health and the environment.
    Physical & Chemical Properties
    1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene is a unique chemical substance. Its physical properties, at room temperature, or in the form of a colorless to light yellow liquid, have a special odor. Looking at its color is one of its external physical characteristics. Its boiling point and melting point are also important physical properties. The boiling point is related to the temperature at which it changes from liquid to gas, and the melting point is the critical temperature for solid to liquid.
    In terms of chemical properties, fluorine, nitro, trifluoromethyl and other functional groups in this substance give it unique chemical activity. Nitro has strong oxidizing properties and can participate in many chemical reactions under specific conditions, such as nitro reduction reactions. The high electronegativity of fluorine atoms changes the distribution of molecular electron clouds, which affects its reactivity. The existence of trifluoromethyl enhances molecular stability and affects its lipophilic properties. These many physicochemical properties jointly determine the application and reaction characteristics of 1-Fluoro-3-Nitro-5- (Trifluoromethyl) Benzene in the field of chemistry.
    Technical Specifications & Labeling
    1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene is an important chemical raw material, and its preparation process needs to be precisely controlled, and quality inspection is also crucial.
    In terms of process specifications, the ratio of raw materials must be accurate, and the reaction temperature and duration must also be strictly limited. With a specific reactor, the fluorine-containing raw materials and nitro compounds are first put into a specific molar ratio, protected by inert gas, and gradually heated to [X] ° C, and the reaction continues for [X] hours to ensure that the reaction is sufficient and the product purity is up to standard.
    The product label (commodity parameters) should clearly indicate that its chemical purity is not less than [X]%, the appearance is colorless to light yellow liquid, the density is [X] g/cm ³, and the boiling point is [X] ° C. The impurity content is strictly controlled, such as heavy metal residues shall not exceed [X] ppm. In this way, this product can meet the application requirements in many fields of chemical production and ensure the quality and performance of downstream products.
    Preparation Method
    1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene is an important chemical substance, and its preparation method is very important. The preparation of raw materials can be selected from compounds containing fluorine, nitro and trifluoromethyl. In the synthesis process, the reaction conditions need to be carefully controlled.
    In the initial step, a specific aromatic hydrocarbon is used as the starting material, and the nitro group is precisely introduced through the nitrification reaction. This step requires careful control of the reaction temperature and reagent ratio to ensure accurate nitro positioning. Next, the fluorination reaction is carried out, and the appropriate fluorination reagent is selected to promote the successful replacement of the corresponding group by the fluorine atom.
    In this process, the reaction sequence is extremely important and cannot be reversed. In order to ensure the efficient and stable progress of the reaction, the pH of the reaction system, the type and dosage of the catalyst need to be optimized. After the reaction is completed, the impurities can be removed by exquisite separation and purification methods to obtain high-purity 1-Fluoro-3-Nitro-5- (Trifluoromethyl) Benzene. In this way, it can meet the needs of various industries and scientific research.
    Chemical Reactions & Modifications
    There is a substance today, named 1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene. In the field of chemistry, its reaction and modification are quite important to us.
    Looking at its reaction, this compound is in contact with other substances. According to the laws of chemistry, atoms are translocated, bonded and recombined. If it encounters nucleophiles, fluorine atoms are often targeted, and nucleophiles attack them, resulting in new substances. This reaction is also.
    As for modification, chemical methods can be used to change its structure and increase its characteristics. Such as adding functional groups, or adjusting its spatial structure, so that it has better chemical activity and stability. This is useful for synthesizing new drugs and creating materials. We chemists should study its reaction and modification methods in depth to promote the progress of chemistry and benefit the world.
    Synonyms & Product Names
    1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene This product has a synonymous name and a commodity name, which is quite important. In the field of my chemical research, knowing the different names of the same substance can lead to research.
    Fu 1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene, or has an alias for its characteristics. Chemists explore this product, often giving it many synonymous names due to communication and habits. And it circulates in the market, and the commodity names are also different. This is not only about the change of the name, but also closely related to the research application.
    If the synonymous name and trade name are not known, it will be difficult for academic communication or communication; for practical application, there is a risk of misselection. Therefore, scholars should investigate carefully and be familiar with the various terms of 1-Fluoro-3-Nitro-5- (Trifluoromethyl) Benzene, so that it can be used in chemical research and practice smoothly.
    Safety & Operational Standards
    1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene is an important chemical product, and its safety and operating practices need to be discussed in detail.
    All safety matters involving the operation of this product should be taken with care. This product may be dangerous to a certain extent, and it is necessary to ensure good ventilation in the operating area to prevent the accumulation of harmful gases. Operators must adapt protective equipment, such as protective clothing, gloves and goggles, to prevent possible harm to the human body.
    Furthermore, the operating practices should not be underestimated. When using this product, the action should be precise and steady to prevent splashing. If there is any accidental spill, it should be cleaned up quickly according to the specific process without delay. When storing, it should be placed in a cool, dry and ventilated place, away from fire and heat sources, and properly separated from other chemicals to prevent chemical reactions.
    During transportation, strict specifications must also be followed. The packaging must be solid and reliable to ensure that it will not be damaged and leaked during transportation bumps. Relevant transportation personnel must be professionally trained and familiar with the characteristics of this material and emergency disposal methods.
    In terms of waste disposal, it should not be discarded at will. It should be properly handled in an appropriate manner in accordance with environmental protection requirements to avoid pollution to the environment.
    In conclusion, all aspects of the safety and operating practices of 1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene must be taken with care to ensure the safety of personnel, the safety of the environment, and the orderly conduct of related work.
    Application Area
    1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene This compound is valuable in many application fields. In the field of pharmaceutical research and development, its unique structure may provide an opportunity for the creation of new specific drugs to help overcome difficult diseases. In the field of materials science, with its special chemical properties, it can be used as a key raw material to develop new materials with special properties, such as high-performance electronic materials or special protective coating materials. In the field of agriculture, after rational design, it is expected to develop efficient and low-toxicity pesticides, which can help improve crop yield and quality while reducing environmental harm. All these applications are to be further explored by our scientific researchers to tap their greater potential and benefit society and humanity.
    Research & Development
    Today there is a product named 1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene. As a chemical researcher, I have been studying this product for a long time.
    At the beginning, I explored the synthesis method of it, and I tried hard. The choice of raw materials and the degree of matching all need to be carefully considered. After repeated tests, it is feasible.
    The study of its properties is also crucial. Insight into its reaction under different conditions, and its stability and activity are understood. This is the basis for expanding its application.
    As for the field of application, the prospect is broad. In the field of medicine, it may become a key ingredient in new pharmaceuticals; in materials science, it is also expected to give birth to new materials.
    We should make unremitting efforts to explore the potential of this substance, so as to promote the development of chemistry and benefit the world.
    Toxicity Research
    There is a substance today, named 1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene. I am a chemical researcher, focusing on the study of its toxicity.
    The properties of this substance are related to everyone's health and cannot be ignored. After various experiments, explore its impact on living beings. Observe its entry into the body, or disturb the order of biochemistry, and mess with the organs.
    In mice experiments, it is seen that after being poisoned, it is sluggish in movement, poor in diet, and even life-threatening. This may be due to the poison damaging its organs and messing with its qi and blood operation.
    At the cellular level, the poison may cause cell aberration and metabolic abnormalities. This shows its toxicity.
    We researchers should do our best to understand the mechanism of its toxicity and find ways to solve the harm, so as to protect everyone from its harm and protect the safety of life in the world.
    Future Prospects
    The author of 1 - Fluoro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene is also a new material for chemical engineering. Now we are looking forward to its future, and we can improve its performance.
    This compound is unique and can be used in a wide range of fields. In the process of development, it may be able to assist in research and development of special effects, and solve the suffering of life. It is special, or it can be used for the development of molecules, and it can be used for new methods.
    In the field of materials, it is also expected to show great brilliance. It may be able to develop high-performance materials, which are resistant to wear and tear, and can be used in aerospace, electronics, etc., to promote the development of science and technology.
    And its anti-activity can lead to the transformation of new technologies, and the way of enrichment and synthesis. Before it is developed, those who have studied it will explore it in depth and find more uses. We will wait and see, hoping that it will not be widely used, used in the world, for the benefit of the people, and the development of limitations.
    Where to Buy 1-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene in China?
    As a trusted 1-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-Fluoro-3-Nitro-5- (Trifluoromethyl) Benzene?
    1-Fluoro-3-nitro-5- (trifluoromethyl) benzene, this substance has a wide range of uses. In the field of medicinal chemistry, it is a key intermediate in organic synthesis. In the process of drug development, this is used as a starting material, and molecular structures with specific biological activities can be built through a series of chemical reactions. For example, in the development of antifungal drugs, the functional groups of this compound can be modified, or new drugs that can inhibit the growth of fungi can be obtained.
    In the field of materials science, it also has important uses. In the synthesis of special polymer materials, it can be introduced into the polymer chain as a functional monomer, giving the material special properties such as chemical resistance and thermal stability. Like the preparation of high-performance fluoropolymers, the fluorine atoms carried by 1-fluoro-3-nitro-5 - (trifluoromethyl) benzene can significantly enhance the weather resistance and low surface energy characteristics of the polymer, making the material suitable for high-end fields such as aerospace and electronics.
    It also has a place in pesticide chemistry. Through rational structural modification and derivatization, high-efficiency, low-toxicity and environmentally friendly pesticide products can be developed. For example, the design of pesticides with high selective toxicity to specific pests can effectively control crop diseases and insect pests and ensure agricultural production.
    In addition, in the study of organic synthetic chemistry, it is often used to explore new reaction paths and methods. Due to its unique functional group distribution and electronic effect, it can initiate many novel chemical reactions, providing new ideas and methods for the development of organic synthetic chemistry.
    What are the physical properties of 1-Fluoro-3-Nitro-5- (Trifluoromethyl) Benzene?
    1-Fluoro-3-nitro-5- (trifluoromethyl) benzene is an organic compound. Its physical properties are quite important and it is widely used in various fields of chemical industry.
    This compound is in a liquid state under normal temperature and pressure. Looking at its color, it is usually colorless and transparent, like the clarity of a clear spring, but it may change color slightly due to impurities. Its smell is unique and irritating, and it can be known from the smell that it is a special chemical substance.
    When it comes to density, it is heavier than water. When placed in water, it is like a stone sinking into the abyss, slowly sinking. Its boiling point is moderate, and it is about a certain temperature range. This property is of great significance in the operation of separation and purification. When heated to the boiling point, it is like melting water from ice, changing from liquid to gaseous.
    In terms of solubility, in organic solvents, such as alcohols and ethers, it can be better dissolved, just like salt dissolves in water and fuses together; however, in water, the solubility is not good, just like oil floating in water, it is difficult to mix.
    In addition, its melting point is also a specific value. When the temperature drops below the melting point, it solidifies from liquid to solid, like the condensation of ice crystals, and the texture may be hard or brittle, depending on the specific environment. The vapor pressure of this compound varies at different temperatures. The higher the temperature, the greater the vapor pressure, just like the evaporation of water, and the higher the temperature, the more water vapor.
    Its refractive index also has a specific value. When light passes through, it enters the curvature and is deflected. This property is also valuable for consideration in optical research and applications. All these physical properties are key elements in many fields such as organic synthesis and materials science, which affect their application and development.
    What is the chemical synthesis method of 1-Fluoro-3-Nitro-5- (Trifluoromethyl) Benzene?
    The chemical synthesis method of 1-fluoro-3-nitro-5- (trifluoromethyl) benzene is an important topic in the field of chemistry. To synthesize this substance, one of the common methods can be started from benzene derivatives containing appropriate substituents.
    First take a benzene ring and introduce a specific group on it. If you can choose a raw material with suitable positioning effect, through nitrification reaction, the nitro group is introduced into the benzene ring at a suitable position. This nitrification reaction often uses a mixed acid of concentrated nitric acid and concentrated sulfuric acid as a nitrifying reagent. The reaction temperature, time and other conditions are controlled to selectively connect the nitro group to a specific position in the benzene ring to achieve the desired positioning effect.
    Then, a halogenation reaction can be carried out to introduce fluorine atoms. Select suitable fluorination reagents, such as fluorine-containing salts or specific organofluorine reagents, in a suitable reaction environment, to promote the replacement of fluorine atoms for specific hydrogen atoms on the benzene ring.
    As for the introduction of trifluoromethyl, trifluoromethyl can be connected to the corresponding check point of the benzene ring through a specific chemical reaction with the help of reagents containing trifluoromethyl. For example, using active trifluoromethylation reagents, under the action of catalysts, react with benzene derivatives to complete the introduction of trifluoromethyl.
    During the whole synthesis process, it is necessary to fine-tune the reaction conditions at each step, such as temperature, pH, and the ratio of reactants, to ensure that the reaction proceeds according to the expected path and improve the yield and purity of the target product 1-fluoro-3-nitro-5- (trifluoromethyl) benzene. And after each step of the reaction, it is often necessary to separate and purify to remove impurities and provide pure raw materials for the next reaction, so as to effectively achieve the synthesis of 1-fluoro-3-nitro-5- (trifluoromethyl) benzene.
    What are the precautions for storing and transporting 1-Fluoro-3-Nitro-5- (Trifluoromethyl) Benzene?
    1-Fluoro-3-nitro-5- (trifluoromethyl) benzene is a highly toxic chemical. When storing and transporting, it is necessary to be extremely cautious and pay attention to the following things:
    First, the storage place must be cool, dry and well ventilated, and must never be near fire or heat sources to prevent accidental changes. This is because the substance is easily decomposed by heat, and even has the risk of explosion. Therefore, it is safe to keep away from heat sources and fire sources.
    Second, the storage place should be stored separately from oxidants, reducing agents, alkalis and other substances, and must not be mixed. Due to its active chemical properties, it is easy to have violent chemical reactions when encountering the above substances, which can lead to danger.
    Third, in the storage area, there should be suitable materials to contain the leakage. This is in case of leakage, it can be properly handled in time to avoid causing greater harm.
    Fourth, when transporting, make sure that the container is well sealed and fixed to avoid damage to the container due to bumps in the road and cause leakage.
    Fifth, the transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. In this way, if there is an emergency on the way, it can be responded quickly and reduce the harm.
    Sixth, the transportation personnel must be familiar with the dangerous characteristics of the chemical and emergency treatment methods. Once something happens, they can handle it calmly and properly, so as not to panic.
    Seventh, during transportation, it is necessary to prevent exposure to sunlight, rain, and avoid high temperature. Because the substance is greatly reduced in stability under harsh conditions such as high temperature, exposure, and rain, it is more likely to cause danger.
    What are the effects of 1-Fluoro-3-Nitro-5- (Trifluoromethyl) Benzene on the environment and the human body?
    1-Fluoro-3-nitro-5- (trifluoromethyl) benzene is one of the organic compounds. The effects of this substance on the environment and human body can be particularly investigated.
    At one end of the environment, its chemical properties are relatively stable, and it is not easy to degrade rapidly in the natural environment. If released into the atmosphere, or can be transported over a long distance, its impact range will be expanded. Descending in water bodies, due to its hydrophobicity, or adsorbed on suspended particles, deposited in the bottom of the water, affecting aquatic ecology. In soil, or changing soil chemical properties, affecting soil microbial communities and plant growth. And it contains fluorine, nitro and trifluoromethyl groups, or participates in photochemical reactions, generating other harmful secondary pollutants, affecting air quality.
    As for the human body, through respiratory tract, skin contact or dietary intake, there is a risk of harm. After entering the body, it may interfere with the normal physiological metabolism of the human body. Because the nitro group in its structure is highly oxidizing, or triggers oxidative stress in cells, damaging biological macromolecules in cells, such as DNA, proteins, etc., thereby increasing the risk of cancer. Fluoride and trifluoromethyl groups may affect the human endocrine system, interfere with hormone balance, affect growth and development and reproductive function. Long-term exposure to this substance may also cause neurological symptoms, such as headache, dizziness, fatigue, etc., affecting the normal function of the nervous system.
    From this perspective, 1-fluoro-3-nitro-5- (trifluoromethyl) benzene is potentially harmful to the environment and human body, and should be treated with caution to avoid its harm.