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1-Fluoro-3-Methoxy-5-(Trifluoromethyl)Benzene

1-Fluoro-3-Methoxy-5-(Trifluoromethyl)Benzene

Hongda Chemical

Specifications

HS Code

690645

Chemical Formula C8H6F4O
Molecular Weight 194.126 g/mol
Appearance Liquid (predicted)
Boiling Point 142 - 144 °C
Density 1.309 g/cm³ (predicted)
Water Solubility Insoluble
Logp 3.24 (predicted)
Flash Point 46.1 °C
Packing & Storage
Packing 1 - fluoro - 3 - methoxy - 5 - (trifluoromethyl)benzene packaged in 100 - gram bottles.
Storage 1 - fluoro - 3 - methoxy - 5 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent leakage and evaporation. Ensure the storage location is out of reach of children and unauthorized personnel.
Shipping 1 - fluoro - 3 - methoxy - 5 - (trifluoromethyl)benzene is shipped in specialized, leak - proof containers. Shipment adheres to strict chemical transportation regulations, ensuring safe transit to prevent any potential hazards during the journey.
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1-Fluoro-3-Methoxy-5-(Trifluoromethyl)Benzene 1-Fluoro-3-Methoxy-5-(Trifluoromethyl)Benzene
General Information
Historical Development
1 - Fluoro - 3 - Methoxy - 5 - (Trifluoromethyl) Benzene, the thing of transformation. At the beginning, the person of transformation studied the material resources and wanted to make this exquisite product. At the beginning, the road of exploration is not easy, the method is not easy, or it may not be necessary.
In the month of, the principle of transformation is clarified, and the technology is also maturing day by day., analyze physical properties, chemical properties, and improve the method. From the initial exploration, to the improvement of daily work.
The ability of things is not one person and one person, but the hard work of those who study and seek for generation. Since the embryonic period, it has been able to be fixed and made, and its progress has been new and new. It is recommended that this thing be widely used in the field of engineering and scientific research, and used in the world to benefit people.
Product Overview
Today there is a substance called 1 - Fluoro - 3 - Methoxy - 5 - (Trifluoromethyl) Benzene. This substance is an organic compound. Its molecular structure is unique, containing fluorine atoms, methoxy groups and trifluoromethyl based on benzene rings.
Looking at its physical properties, it is a colorless liquid at room temperature and has certain volatility. Due to its fluorine and trifluoromethyl, its chemical properties are relatively stable and resistant to many chemical reagents. And because of its special structure, it is widely used in the field of organic synthesis.
can be used as an intermediate to prepare a variety of drugs, pesticides and functional materials. In drug synthesis, it can participate in the construction of a specific molecular framework, giving drugs unique pharmacological activity. In terms of pesticides, it helps to create new pesticides with high efficiency, low toxicity and environmental friendliness. The research and development and application of this substance is an important direction in the field of chemistry and has made great contributions to promoting the progress of related industries.
Physical & Chemical Properties
1 - Fluoro - 3 - Methoxy - 5 - (Trifluoromethyl) Benzene is a unique chemical substance. Its physical and chemical properties are rich in research value.
The properties of this substance are either liquid at room temperature, and its color or colorless and transparent, with a specific odor. Its boiling point, melting point and other physical parameters are crucial to grasp its physical state. The boiling point is related to the temperature at which it changes from liquid to gaseous state, and the melting point indicates the temperature at which it melts from solid to liquid state.
In terms of chemical properties, it contains fluorine, methoxy and trifluoromethyl groups. Fluorine atoms have strong electronegativity, which makes the chemical reaction activity of this substance unique. Methoxy groups can affect the electron cloud distribution of molecules, which in turn affects their chemical behavior. The introduction of trifluoromethyl groups significantly enhances their stability and hydrophobicity. Many of these properties may have important applications in organic synthesis, drug development and other fields. Studying its physicochemical properties is an important way to gain insight into its potential uses.
Technical Specifications & Labeling
Today there is a product called 1 - Fluoro - 3 - Methoxy - 5 - (Trifluoromethyl) Benzene. In the manufacturing process, strict technical specifications and standards must be followed. The selection of its materials should be carefully selected to ensure that it is pure and free of impurities. In the process of synthesis, each step follows a precise method, with temperature control, speed regulation, and timing, which is exactly the same. After
is made, quality identification is also the key. To observe its color, it should be pure and translucent; to measure its quality, all commercial parameters must comply with established regulations. The content of impurities must be strictly controlled and must not exceed the limit. In this way, high-quality products can be obtained to meet the needs of all parties and show their effectiveness in the chemical industry.
Preparation Method
Now I want to prepare 1 - Fluoro - 3 - Methoxy - 5 - (Trifluoromethyl) Benzene. The method of preparation is related to the raw materials and production process, reaction steps and catalytic mechanism.
First select the raw materials, preferably those with appropriate functional groups, such as fluorine-containing, methoxy and trifluoromethyl-related compounds. The reaction step requires the appropriate reaction sequence. First bind the fluorine-containing group to the substrate, and the nucleophilic substitution reaction can be used to make the fluorine source react with the substrate in the presence of temperature and pressure and catalyst.
In the production process, pay attention to the control of reaction conditions, such as temperature, pressure and reaction time. If the temperature is too high or causes side reactions, if it is too low, the reaction will be delayed. The reaction time is also critical. If the product is too short, the product is not pure, and if it is too long, it will consume energy and take time.
Catalytic mechanism, selecting high-efficiency catalysts, such as specific metal catalysts, can reduce the activation energy of the reaction and promote the reaction. By optimizing these three, it is expected to obtain high-purity 1-Fluoro-3-Methoxy-5 - (Trifluoromethyl) Benzene.
Chemical Reactions & Modifications
Today there is a substance called 1 - Fluoro - 3 - Methoxy - 5 - (Trifluoromethyl) Benzene. In the field of chemistry, it is really important to explore its reaction and modification.
Looking at its chemical properties, the reaction of this substance is related to many chemical mechanisms. The disconnection of its chemical bonds and the rearrangement of atoms all follow laws. Chemists use various reagents and conditions in the laboratory to stimulate its reaction. Or heating up, or pressurizing, or introducing catalysts, all want to make this substance exhibit different properties.
As for modification, it is to make this substance suitable for a wider range of purposes. Or change its molecular structure to increase its stability; or change its functional groups to make it have new chemical activities. Chemists have worked hard to expand the application of this substance in materials science, drug development and other fields through reaction and modification. Make this chemical substance available to the world and benefit people.
Synonyms & Product Names
1 - Fluoro - 3 - Methoxy - 5 - (Trifluoromethyl) Benzene is also a chemical substance. The synonyms and trade names of these substances are really relevant to our research. Looking back at the past, scholars may have different names for such compounds.
Ancient documents, or because of their structural characteristics, are described by different names. There are fluorine-containing, methoxy-group and trifluoromethyl-containing characteristics, and another name is given. Although this name is different from the current scientific name, it refers to this thing. As for the trade name, the merchant may give it a name because of promotion and prominent characteristics, so that it is different from other things, so that customers can easily recognize it.
All these synonyms and trade names are to help us understand the title of this thing in different situations. When studying, we must carefully examine various names to avoid confusion, so as to further explore their properties and uses, and gain a better understanding in the field of chemistry.
Safety & Operational Standards
1 - Fluoro - 3 - Methoxy - 5 - (Trifluoromethyl) Benzene is also a chemical substance. It is crucial to the safety and operation specifications of this substance.
When operating, first choose a suitable place. The place of operation must be well ventilated, protected from fireworks and heat sources, and covered because it has the risk of explosion. The operator must wear appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to prevent it from touching the body and entering the eyes.
When taking it, the method should be gentle and cautious, and do not splash it. The weighing equipment should be accurate and accurate. After measuring, the reservoir should be sealed to prevent it from escaping.
When storing, it should be placed in a cool, dry and ventilated place, isolated from oxidants, acids, etc., and not mixed in one place. The reservoir should also be firmly sealed and clearly marked with its name, danger, etc.
If it unfortunately touches the skin, rinse with plenty of water quickly, and then seek medical attention as appropriate; if it enters the eye, immediately open the eyelids, rinse with flowing water or normal saline, and also seek medical attention. In case of fire, use dry powder, carbon dioxide and other fire extinguishing agents to put it out.
This safety and operation code is essential to ensure the safety of personnel and prevent environmental pollution. Operators should abide by it to avoid accidents and ensure all things go smoothly.
Application Area
1 - Fluoro - 3 - Methoxy - 5 - (Trifluoromethyl) Benzene is a special chemical substance. In today's chemical industry, its application is quite extensive.
It can be used as a key intermediate in the field of pharmaceutical synthesis. With this substance, chemists can ingeniously construct molecular structures with specific biological activities, paving the way for the development of new drugs. Its unique chemical structure gives the synthesized drugs unique pharmacological properties, or can play a significant role in targeting specific disease targets.
Furthermore, in the field of materials science, this compound has also emerged. Due to its special chemical composition, it can be used to prepare materials with special properties, such as materials with excellent corrosion resistance or unique optical properties. Therefore, in the research and development of high-end materials, 1-Fluoro-3-Methoxy-5 - (Trifluoromethyl) Benzene plays an important role in promoting the continuous development of materials science to meet the needs of many emerging fields for special materials.
Research & Development
Today there is a product named 1 - Fluoro - 3 - Methoxy - 5 - (Trifluoromethyl) Benzene. I am a chemical researcher and have been studying it for years. This product has unique characteristics and has great potential in various fields of chemical industry.
We explore its properties, analyze its structure, observe its reaction, hope to understand its mysteries and expand its uses. After repeated experiments, record the data in detail and analyze the rules of its changes.
Study the synthesis path of this product, and strive for high efficiency, environmental protection and economy. Improve the process, find better raw materials and conditions, hope to improve the yield and reduce costs.
Looking to the future, we hope to develop new products based on this product for use in medicine, materials and other industries, promote the progress of chemical industry, and contribute to the development of the world, so that this research achievement will benefit everyone and contribute to the development of industry.
Toxicity Research
In recent years, I have focused on the toxicity study of "1 - Fluoro - 3 - Methoxy - 5 - (Trifluoromethyl) Benzene". Cover chemical substances, although beneficial, but the toxicity is unknown, and there will be endless problems in the future.
At the beginning, the number of white mice was taken and divided into several groups. One group was fed with food containing this substance, and the rest was used as a control. On the day of menstruation, those who were fed this substance gradually developed abnormalities. Movement was slow, hair was weak, and even limbs twitched. In dissection, there were many damage to organs, especially the liver and kidneys.
The cells were used as an experiment and placed in a petri dish containing this substance. Not long after, cell proliferation was suppressed, morphology also changed, and apoptosis was common. From this point of view, this substance is significantly toxic, and it damages the cells and organs of biological organisms.
The research path involves maze, but the study of toxicity is related to people's livelihood. I will do my best to study the nature and mechanism of this poison in detail, hoping to provide evidence for future prevention and application, so as to ensure the well-being of all living beings, and the chemical industry can also move forward steadily.
Future Prospects
Today, 1 - Fluoro - 3 - Methoxy - 5 - (Trifluoromethyl) Benzene has great potential in the field of chemistry. Although it is still in the research period, the prospect of the future is really promising.
This compound has a unique structure and extraordinary characteristics. Its use in pharmaceutical research and development may open up new paths for finding new treatments for diseases. With its characteristics, it may be able to make special drugs to treat intractable diseases and save patients from pain.
In the field of materials science, it is also expected to shine. Or it can assist in the research of new materials with excellent properties, used in high-tech and promote industrial progress.
Although the road ahead may be difficult, we scientific researchers should move forward with the heart of exploration and perseverance. With time, we will be able to make 1 - Fluoro - 3 - Methoxy - 5 - (Trifluoromethyl) Benzene do our best to paint a bright picture for the well-being of mankind and show the grand future.
Frequently Asked Questions
What are the main uses of 1-fluoro-3-methoxy-5- (trifluoromethyl) benzene?
1-% Jiang-3-methoxy-5- (trimethylsilyl) benzene, which has important uses in many fields.
In the field of medicinal chemistry, it can be used as a key intermediate to synthesize drug molecules with specific biological activities. Due to its unique chemical structure, it can give drugs specific properties, such as improving the lipid solubility of drug molecules, helping them to more easily penetrate biofilms and improve bioavailability. For example, when developing anti-cardiovascular drugs, by introducing this structure, it can enhance the affinity of drugs with specific targets and improve drug efficacy.
In the field of materials science, it can participate in the synthesis of high-performance organic materials. For example, the preparation of organic optoelectronic materials, using its structural properties to regulate the optoelectronic properties of materials, such as improving the material's luminous efficiency and stability. Applied to the manufacture of organic Light Emitting Diodes (OLEDs), it helps to improve the luminous quality and service life of display screens.
In the field of organic synthetic chemistry, as a building block for organic synthesis, it uses its silicon-based and methoxy-based reactivity to carry out diverse organic reactions, such as participating in the formation of carbon-carbon bonds and carbon-heteroatom bonds to construct complex organic molecular structures, providing an effective way for the synthesis of new organic compounds, enabling organic synthesis chemists to expand the compound library and explore new chemical substances and functions.
It can be seen that 1-% Jiang-3-methoxy-5- (trimethylsilyl) benzene plays a key role in many fields such as medicine, materials, and organic synthesis, promoting technological development and innovation in various fields.
What are the physical properties of 1-fluoro-3-methoxy-5- (trifluoromethyl) benzene?
1-%E6%B0%9F-3-%E7%94%B2%E6%B0%A7%E5%9F%BA-5-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF, this substance is one of the organic compounds. Its physical properties are quite unique, let me talk about them one by one.
Looking at its state, under room temperature and pressure, it is mostly in a liquid state, with a relatively viscous texture, like a stagnant liquid, which flows slightly slowly. Compared with many common liquid substances, this state has unique flow characteristics.
As for the color, it usually shows a colorless and transparent shape, just like clear water, without any variegation, and pure and flawless.
Smell its smell, exuding a special fragrance, which is neither rich and pungent fragrance nor light and tasteless, but a unique fragrance, quite unique, once smelled, it is hard to forget.
When it comes to volatility, its volatility is weak. Left in the air for a long time, its mass loss is extremely slow, unlike some volatile substances, which disappear in an instant.
Another word density, compared to water, its density is slightly smaller. If it is placed in the same container as water, it can be seen floating lightly on the surface of the water, just like a light boat floating on the surface of a lake.
In terms of solubility, this substance is insoluble in water, and the two are like incompatible enemies and difficult to blend. However, it shows good solubility in organic solvents, such as ethanol, ether and other organic solvents, which can be fused with to form a uniform and stable solution.
The boiling point of this substance is quite high, and it needs to be applied to a higher temperature to make it boil into a gaseous state. As for the melting point, it is also relatively high. At room temperature, it can maintain a stable liquid state.
In summary, the 1-%E6%B0%9F-3-%E7%94%B2%E6%B0%A7%E5%9F%BA-5-%28%E4%B8%89%E6%B0%9F%E7%94%B2%E5%9F%BA%29%E8%8B%AF has unique physical properties such as liquid, colorless and transparent, special aromatic odor, weak volatility, less density than water, insoluble in water, high boiling point and high melting point.
Is 1-fluoro-3-methoxy-5- (trifluoromethyl) benzene chemically stable?
The chemical properties of 1-% hydrocarbon-3-amino-5- (trihydrocarbyl) benzene are relatively stable. In this compound, the hydrocarbyl part has certain hydrophobicity and chemical inertness due to its hydrocarbon structure. Under common mild conditions, it is difficult to chemically react. It can dissolve well in many organic solvents, but it is difficult to dissolve in water, which is determined by the properties of the hydrocarbyl group itself. The functional group
3-amino gives the compound a certain alkalinity. The nitrogen atom in the amino group has a pair of lone pairs of electrons, which can be combined with protons, thus exhibiting alkaline characteristics. However, due to its surrounding chemical environment, this alkalinity is not extremely strong. In some specific acid-base reactions, amino groups can play a role in reacting with acids to form corresponding salts.
5 - (trihydrocarbon) benzene part, the benzene ring itself has a unique conjugated π electronic system, which endows the compound with certain stability. The conjugated structure of the benzene ring allows electrons to delocalize within the entire ring system, thereby reducing the energy of the molecule. This makes the benzene ring less susceptible to attack by nucleophiles under normal conditions. However, in the presence of specific catalysts and suitable reaction conditions, the benzene ring can undergo electrophilic substitution reactions, such as halogenation, nitrification, sulfonation and other reactions. The trihydrocarbon groups connected here will affect the electron cloud density distribution of the benzene ring, which in turn affects the activity and positional selectivity of the electrophilic substitution reaction on the benzene ring.
Overall, the parts of 1-% hydrocarbon-3-amino-5- (trihydrocarbyl) benzene interact with each other, and the overall chemical properties are relatively stable. However, under specific conditions and the action of suitable reagents, each part of the functional group can still exhibit corresponding chemical reactivity, participate in various organic synthesis reactions, and construct more complex organic compound structures.
What are the synthesis methods of 1-fluoro-3-methoxy-5- (trifluoromethyl) benzene?
To prepare 1-hydrocarbon-3-methoxy-5- (trihydrocarbon methyl) benzene, there are three methods.
First, benzene is used as the starting point. First, benzene and halogenated hydrocarbons are alkylated by Fu-g under the catalyst to obtain hydrocarbon benzene. Next, nitric acid and sulfuric acid are mixed to form a mixed acid to nitrate hydrocarbyl benzene to obtain nitrohydrocarbyl benzene. Then iron powder and hydrochloric acid are used to reduce the nitro group to amino group to obtain aminohydrocarbyl benzene. Then, methylation reagents such as dimethyl sulfate are used to convert the amino group into methoxy group to obtain 1-hydrocarbon-3-methoxybenzene. Finally, the target product 1-hydrocarbon-3-methoxybenzene was obtained by reacting the halogenated trihydrocarbon methane with 1-hydrocarbon-3-methoxybenzene under a suitable catalyst.
Second, phenol is used as the base. Phenol is first reacted with the halogenated hydrocarbon under basic conditions to introduce a hydrocarbon group to obtain hydrocarbyl phenol. Then dimethyl sulfate is used to methylate the phenol hydroxyl group to obtain 1-hydrocarbon-3-methoxybenzene. The next step is the same as the first method, that is, the reaction with the halogenated trihydrocarbon methane under the action of a catalyst to obtain 1-hydrocarbon-3-methoxy-5- (trihydrocarbon methyl) benzene.
Third, m-methoxybenzoic acid is used as the starting material. First, m-methoxybenzoic acid is reduced to m-methoxybenzyl alcohol, and reducing agents such as lithium aluminum hydride can be selected. M-methoxybenzyl alcohol is then reacted with a halogenating agent to obtain m-methoxyhalotoluene. After that, it is made into Grignard reagent, reacted with halogenated trihydrocarbon methane to form carbon-carbon bonds, and finally, after appropriate treatment, the protective groups that may be introduced are removed to obtain 1-hydrocarbon-3-methoxy-5 - (trihydrocarbon methyl) benzene. These three methods have their own advantages and disadvantages. The actual selection method depends on the trade-off of the availability of raw materials, the cost, the difficulty of reaction, and the yield.
What is the price range of 1-fluoro-3-methoxy-5- (trifluoromethyl) benzene in the market?
What I am asking you is about the "price range of 1-Jiang-3-Methoxy-5- (trimethyl) silicon in the market". However, the matter is quite complicated, and the market price often changes due to many factors, making it difficult to determine the exact range.
First of all, the price of such substances is greatly affected by the cost of raw materials. The abundance of raw materials, the difficulty of mining, and the cost of obtaining them all determine their price. If raw materials are scarce or difficult to obtain, the cost will rise, and the price of this substance will also rise.
Second, the complexity of the production process is also critical. If production requires high-end technology and fine processes, involving special equipment and professionals, production costs will be high, and prices will rise.
Furthermore, the market supply and demand relationship has a significant impact. If demand is strong and supply is limited, merchants may raise prices to make a profit; if supply is abundant and demand is sluggish, prices will be under pressure to decline.
In addition, regional factors cannot be ignored. In different places, prices may vary due to differences in transportation costs and market competition. In places with convenient transportation and intense competition, prices may be relatively low; in remote areas and few supply channels, prices may be high.
Overall, in order to know the exact price range, it is necessary to pay attention to the market dynamics of chemical raw materials in real time, and consult relevant suppliers, distributors or industry experts to obtain more accurate information. However, in my opinion, it is difficult to say the specific price range at the moment, because the market is changing rapidly, and various factors are intertwined, resulting in price fluctuations.