Hongda Chemical
Products
Home  /  Products  / 

1-Fluoro-3-Isocyanato-2-Methylbenzene

1-Fluoro-3-Isocyanato-2-Methylbenzene

Hongda Chemical

Specifications

HS Code

846575

Chemical Formula C8H6FNO
Molecular Weight 151.14 g/mol
Appearance Liquid (usually)
Boiling Point Around 204 - 206 °C
Density Data may vary, around typical aromatic compound density range
Solubility Soluble in common organic solvents like dichloromethane, toluene
Vapor Pressure Low at room temperature
Flash Point Caution, flammable, specific value data - dependent
Hazard Class Irritant, toxic in high concentration, potentially harmful if inhaled or in contact with skin

As an accredited 1-Fluoro-3-Isocyanato-2-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - fluoro - 3 - isocyanato - 2 - methylbenzene: Packed in 1 - kg sealed containers for safe storage.
Storage 1 - fluoro - 3 - isocyanato - 2 - methylbenzene should be stored in a cool, dry, well - ventilated area, away from sources of heat, ignition, and direct sunlight. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from incompatible substances like acids, bases, and reactive compounds to prevent dangerous reactions.
Shipping 1 - fluoro - 3 - isocyanato - 2 - methylbenzene is a chemical. It should be shipped in accordance with hazardous materials regulations. Use appropriate packaging to prevent leaks, and label clearly indicating its nature for safe transportation.
Free Quote

Competitive 1-Fluoro-3-Isocyanato-2-Methylbenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

1-Fluoro-3-Isocyanato-2-Methylbenzene 1-Fluoro-3-Isocyanato-2-Methylbenzene
General Information
Historical Development
1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene is a key compound in the field of organic synthesis. Its origin can be traced back to the early days of organic chemistry. At that time, the chemical sages dedicated themselves to exploring the synthesis path of novel organic molecules.
In the early days, due to technical and cognitive limitations, it was difficult to synthesize this compound. However, with the improvement of chemical technology and the refinement of analytical methods, chemists have gained deeper insights into its structure and properties. After countless experiments and improvements, the synthesis method has been perfected day by day.
Since its inception, 1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene has emerged in many fields such as medicine and materials, promoted the development of related industries, and opened up a new world for chemical research and application. It is a shining pearl in the development of organic chemistry.
Product Overview
1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene is a unique chemical product. It is a key intermediate in the field of organic synthesis. Looking at its structure, fluorine atoms, isocyanate groups and methyl are cleverly arranged based on benzene rings, giving this compound unique chemical activity.
In the synthesis reaction, isocyanate groups can react with many active hydrogen-containing compounds, such as alcohols, amines, etc., to form nucleophilic addition reactions and derive various products. The presence of fluorine atoms, due to the high electronegativity of fluorine, can significantly affect the distribution of electron clouds in molecules, change the physical and chemical properties of compounds, such as improving their stability, or affecting the selectivity of reactions.
This compound has considerable application prospects in the fields of medicine and pesticide creation. Through exquisite synthesis strategies, it can be integrated into complex molecular structures, providing opportunities for the development of new drugs or efficient pesticides, and helping chemical synthesis to a higher level.
Physical & Chemical Properties
1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene is also an organic compound. Its physical and chemical properties are worth studying. Looking at its physical properties, it is liquid at room temperature, has a special odor, and has different solubility in specific solvents. Regarding its chemical properties, fluorine atoms, isocyanate and methyl groups give this compound unique reactivity. The high electronegativity of fluorine atoms often changes the distribution of molecular electron clouds and affects the reaction check point; isocyanate is active, and it is easy to react with compounds containing active hydrogen to form urea derivatives. Methyl groups affect the spatial structure and electronic effects of molecules. The physical and chemical properties of this compound have important applications in the field of organic synthesis, such as the preparation of special functional materials, pharmaceutical intermediates, etc., and it is an object that cannot be ignored in chemical research.
Technical Specifications & Labeling
There is currently 1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene. Its technical specifications and identification (product parameters) need to be detailed.
Looking at this substance, its technical specifications need to be precisely determined. In terms of purity, when it reaches a very high standard, the impurity content must be minimal to meet the requirements. And its physical properties, such as color, morphology, etc., should also be stable and uniform.
On the logo, the product parameters should be clearly identifiable. Key information such as the proportion of each element and chemical properties contained must be clearly identified. In this way, the user can understand it and use it correctly. This is all essential to ensure the quality and application of the product, and should not be slightly sparse.
Preparation Method
1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene is an important compound in organic synthesis. The selection of raw materials is very important for its preparation. O-methylaniline can be selected as the starting material, and the diazonium salt can be prepared by diazotization reaction with sodium nitrite and hydrochloric acid at low temperature.
Then, the diazonium salt reacts with fluoroborate acid to form fluoroborate, which is decomposed by heating to obtain o-fluorotoluene. O-fluorotoluene is then acylated, and acetyl chloride and aluminum trichloride are used as reagents to introduce acyl groups. Then, through oxidation, aminolysis and other steps, amino-containing compounds are prepared. Finally, this amino compound reacts with phosgene under suitable conditions to obtain 1-Fluoro-3-Isocyanato-2-Methylbenzene. The whole preparation process, the control of the conditions of each reaction step, such as temperature, time, reagent dosage, etc., have a great influence on the yield and purity of the product.
Chemical Reactions & Modifications
1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene is an important compound in organic synthesis. Its chemical reaction and modification are related to the performance and application of this product.
In the past, the reaction of this compound was investigated, and more emphasis was placed on the transformation under conventional conditions. However, at present, chemists are trying to find novel ways to improve its performance. After many studies, it is found that a specific catalyst can make 1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene undergo a unique reaction, which greatly improves the properties of the product.
This modified product may have excellent stability and reactivity in the field of materials science. By adjusting the reaction conditions, such as temperature, pressure and reactant ratio, the structure and properties of the product can be precisely regulated. Chemists hope to continue to explore and further reveal the reaction mechanism of 1-Fluoro-3-Isocyanato-2-Methylbenzene, paving the way for its wide application and shining in many fields.
Synonyms & Product Names
1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene is of unique significance in the field of my chemical research. Its synonyms and trade names are also the key to the research.
In the past, the names of chemical substances often differed depending on regions and schools. This 1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene, or is nicknamed for its characteristics and structure. It is nicknamed for its combination of fluoride, isocyanate, methyl and benzene rings. This is named after its chemical structure, so that researchers can know its properties when they hear its name.
As for the name of the product, the merchant will also give it a unique name in order to recognize its characteristics and uses. Or highlight its efficiency in a specific reaction, or emphasize its purity to attract users. Although these synonyms and the name of the product are different, they refer to this thing, just like all roads, and they all belong to the same place. In the process of chemical research and application, it is clear that its synonyms and the name of the product can be unimpeded and not confused, so as to achieve the precision of research and application.
Safety & Operational Standards
1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene is an important chemical product. Its safe production and operation practices need to be investigated in detail.
This product is dangerous. Its chemical properties are active, and it may cause combustion and explosion in case of open flames, hot topics or contact with oxidants. Therefore, when storing, it must be placed in a cool and ventilated warehouse, away from fire and heat sources, and should be stored separately from oxidants and food chemicals, and should not be mixed. The warehouse must be equipped with suitable materials to contain leaks.
When operating, the operator should be specially trained and strictly abide by the operating procedures. It is recommended that operators wear self-priming filter gas masks (full masks), tape gas suits, and rubber gloves to avoid direct contact. During handling, it should be handled lightly to prevent damage to packaging and containers.
In the unfortunate event of a leak, personnel in the spill-contaminated area should be quickly evacuated to a safe area and quarantined, and access should be strictly restricted. Emergency personnel should wear self-contained positive pressure respirators and protective clothing. Cut off the source of the leak as much as possible to prevent it from flowing into restricted spaces such as sewers and drainage ditches. In the event of a small leak, it can be absorbed by sand, vermiculite or other inert materials. Large leaks require embankment or pit containment, covered with foam to reduce vapor hazards, and then transferred to a tanker or special collector by pump, recycled or transported to a waste treatment site for disposal.
Only by strictly following the above safety and operating practices can we ensure the safety of 1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene related operations, avoid accidents, and ensure the safety of people and the environment.
Application Area
1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene is a unique chemical substance. In the field of chemical industry, it has a wide range of applications. This substance is often a key raw material in the field of organic synthesis.
According to the records of Guanfu in the past, it plays an important role in the creation of organic compounds with specific structures. Due to the characteristics of fluorine atoms, isocyanates and methylbenzene structures, it can lead to unique reaction paths. In the preparation of fine chemicals, such as the creation of special dyes and pharmaceutical intermediates, 1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene can be used as a starting material, and through clever reaction steps, the desired product can be obtained. It may also have potential applications in the field of materials science, providing possible avenues for the development of new functional materials and assisting in the development of innovative material categories to meet the increasingly demanding needs in many fields.
Research & Development
Today there is a substance called 1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene. I am a chemical researcher and have been studying it for a long time.
Looking at this substance, its structure is unique and its properties can also be investigated. During the research process, I carefully observed its reaction mechanism and explored the changes under various conditions. After repeated experiments, I know the law of its interaction with other substances, which is of great potential value in chemical synthesis and other fields.
In order to promote its development, I am committed to optimizing the preparation method, hoping to improve the yield and simplify the process. It also considers its safety and environmental protection, hoping to make this substance more stable and green in industrial applications.
With time and unremitting research, 1-Fluoro-3-Isocyanato-2-Methylbenzene will be able to play a greater role, contribute to the development of chemical industry, and bloom in many fields.
Toxicity Research
1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene is a special chemical product. We focus on toxicity studies and explore in detail. This substance has a unique chemical structure, and its toxic effects cannot be ignored.
After many experimental observations, if this compound accidentally touches the skin, it may cause redness, swelling, itching, and burning. If inhaled, its volatile gas can cause cough, asthma, and severe respiratory damage, endangering life.
Furthermore, ingestion of this substance can also cause serious harm to the digestive system, causing vomiting, abdominal pain, etc. In the environment, it may also affect the ecological balance and pose a potential threat to surrounding organisms.
Therefore, the toxicity study of 1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene is very important, warning everyone to be cautious and take proper protection to avoid its harm.
Future Prospects
1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene is also a chemical. Our research has not yet developed its grand path.
This compound has many properties and is common. Its molecules are exquisite, containing fluorine, cyanate and other groups, and interact with each other.
Unknown, hope to make good use of its properties. In the field of, or can be used to make special effects, to attack and cure diseases; in terms of materials, or can be used to create new materials, with extraordinary properties, used in general utensils. Or in chemical synthesis, to create new reactions and explore new things, unprecedented things. Our unremitting exploration will surely enable 1 - Fluoro - 3 - Isocyanato - 2 - Methylbenzene to be widely used and benefit the world.
Where to Buy 1-Fluoro-3-Isocyanato-2-Methylbenzene in China?
As a trusted 1-Fluoro-3-Isocyanato-2-Methylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-3-Isocyanato-2-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Fluoro-3-Isocyanato-2-Methylbenzene?
1-Fluoro-3-isocyanate-2-methylbenzene, this is an organic chemical with a wide range of uses. In the field of materials science, it is often used as a key monomer in the synthesis of special performance polymers. Because it contains isocyanate groups, it has high activity and can react with active hydrogen compounds such as polyols to form polyurethane materials. This polyurethane material is widely used in coatings, adhesives, foam plastics and other industries. Taking coatings as an example, the polyurethane paint synthesized with it has good wear resistance, corrosion resistance and decorative properties, and can be used for surface coating of automobiles, furniture and other surfaces.
In the field of organic synthesis chemistry, 1-fluoro-3-isocyanate-2-methylbenzene is an important intermediate. Its fluorine atoms and isocyanate groups can participate in various chemical reactions to build complex organic compounds. For example, isocyanate groups can react with amine compounds to form urea derivatives, and fluorine atoms can be introduced into other functional groups through nucleophilic substitution reactions to help synthesize organic molecules with special biological activities or physical properties, providing key raw materials for the development of new drugs and the creation of functional materials.
In addition, in the field of fine chemicals, it can be used to prepare special functional additives. Due to its unique structure, it can endow products with special properties such as improving material surface properties and improving heat resistance. Adding additives containing this structure in plastic processing may improve the processing properties and physical and mechanical properties of plastic products. In short, 1-fluoro-3-isocyanate-2-methylbenzene plays a significant role in many fields of chemical industry, and is of great significance for promoting material innovation and the development of fine chemicals.
What are the physical properties of 1-Fluoro-3-Isocyanato-2-Methylbenzene?
1-Fluoro-3-isocyanate-2-methylbenzene, this is an organic compound. Its physical properties are worth exploring.
Looking at its appearance, under normal temperature and pressure, it is often colorless to light yellow liquid, clear and with certain fluidity. This state is convenient for transmission and operation in many chemical processes.
When it comes to boiling point, it is about a certain temperature range. The value of boiling point is closely related to the intermolecular forces, and its molecular structure causes the interaction between molecules to have a specific strength, so it determines the transition from liquid state to gas state at a specific temperature. The characteristics of boiling point are crucial in chemical operations such as distillation and separation, and can be used to achieve phase separation from other substances with different boiling points.
Melting point is also one of the important physical properties. This compound will condense from liquid to solid under specific low temperature conditions, and this temperature is the melting point. The melting point is also affected by molecular structure and interactions, which guides the setting of storage and transportation conditions to prevent the temperature from being too low to cause it to solidify and affect the use.
Furthermore, density is also a property that cannot be ignored. Its density determines the mass within a specific volume. When it comes to mixing, blending, etc., precise knowledge of density helps to accurately control the proportion of each component.
In terms of solubility, 1-fluoro-3-isocyanate-2-methylbenzene exhibits a certain solubility in organic solvents, such as common aromatic hydrocarbons and halogenated hydrocarbons, but has poor solubility in water. This difference in solubility provides a basis for its selection in different chemical reaction systems and separation and purification processes.
In addition, the compound is volatile and will evaporate slowly in air. This property needs to be paid attention to when using and storing to prevent its escape and cause loss or safety problems.
What is the chemistry of 1-Fluoro-3-Isocyanato-2-Methylbenzene?
1-Fluoro-3-isocyanate-2-methylbenzene, an organic compound, has unique chemical properties and contains many fascinating aspects.
In its molecular structure, the introduction of fluorine atoms endows the compound with unique electronic effects. The fluorine atom has a high electronegativity, which affects the electron cloud density distribution of the benzene ring, reducing the electron cloud density of the adjacent and para-sites of the benzene ring. Therefore, in the electrophilic substitution reaction, the reaction activity may change compared with the unfluorinated similar compounds. In general, electrophilic reagents tend to attack positions with relatively high electron cloud density. In this case, meta-sites are relatively more susceptible to electrophilic reagents, but the specific reaction check point still depends on the reaction conditions.
And isocyanate (-NCO) is an extremely active functional group. It easily reacts with compounds containing active hydrogen, such as alcohols and amines. When reacted with alcohols, carbamate compounds can be formed, which is widely used in the synthesis of polyurethane materials. Reacting with amines generates urea compounds, which are of great significance in the field of organic synthesis and material preparation. In addition, isocyanates are also sensitive to water, and hydrolysis reactions occur in contact with water to form amines and carbon dioxide, which may affect the storage and use of compounds.
Furthermore, the methyl group attached to the benzene ring will increase the electron cloud density of the benzene ring, which affects the electrophilic substitution reaction activity to a certain extent. At the same time, the steric resistance effect of methyl groups will also affect the molecular reaction performance, and in some reactions involving spatial factors, the reaction selectivity may be changed.
Overall, the functional groups of 1-fluoro-3-isocyanate-2-methylbenzene interact with each other, exhibit unique chemical properties, and have potential application value in many fields such as organic synthesis and materials science. However, its active functional group characteristics also require careful operation during storage and use, and attention to precise control of reaction conditions.
What are 1-Fluoro-3-Isocyanato-2-Methylbenzene synthesis methods?
The common methods for synthesizing 1-fluoro-3-isocyanate-2-methylbenzene are as follows.
First, the corresponding aniline derivative is used as the starting material. First, aniline is subjected to diazotization reaction, which is a classic organic reaction step. Under appropriate reaction conditions, aniline is reacted with sodium nitrite and acid reagents to form diazonium salts. Then, using the reactivity of diazonium salts, it undergoes a substitution reaction with fluorine-containing reagents to introduce fluorine atoms. Then, through a specific reaction path, the amino group is converted into isocyanate. This process requires fine regulation of reaction conditions, such as temperature, pH, and reagent ratio, in order to improve the selectivity and yield of the reaction.
Second, it can be started from halogenated benzene derivatives. Select the appropriate halogenated benzene and introduce the methyl group first. This can be achieved by Fu-gram alkylation reaction, in the presence of Lewis acid catalyst, the halogenated benzene interacts with the methylating reagent. After that, a halogen-fluorine exchange reaction is carried out to introduce fluorine atoms. Finally, the isocyanate structure is constructed through a specific reaction process. In this path, the choice of halogenated benzene, the type and amount of catalyst have a great influence on the reaction process.
Third, benzaldehyde derivatives are used as the starting materials. First, a series of modifications are carried out on benzaldehyde, such as the introduction of methyl and other necessary functional groups. Subsequently, the aldehyde group is converted into other intermediate functional groups through an appropriate reaction, and then fluorine atoms and isocyanates are gradually introduced through a multi-step reaction. This method requires precise control of the reaction sequence and reaction conditions of each step in order to achieve effective synthesis of the target product.
The above synthesis methods have their own advantages and disadvantages. In practical application, the appropriate synthesis path needs to be carefully selected according to the specific experimental conditions, raw material availability and purity requirements of the target product.
What are the precautions in storage and transportation of 1-Fluoro-3-Isocyanato-2-Methylbenzene?
1-Fluoro-3-isocyanate-2-methylbenzene is a chemical substance. When storing and transporting, be careful and pay attention to many matters.
First words storage. This chemical is dangerous and needs to be stored in a cool and ventilated warehouse. Due to high temperature, or its chemical properties are unstable, causing danger. The temperature of the warehouse should be controlled in a specific range, and it must not be heated. And it needs to be kept away from fire and heat sources. Open flames can easily cause violent reactions. Furthermore, it should be stored separately from oxidizing agents, acids, alkalis, etc., and cannot be mixed. If it reacts with them or chemically, there is an unpredictable danger. The storage place should also be equipped with suitable materials to contain the leakage, just in case.
Times and transportation. During transportation, it is necessary to ensure that the container does not leak, collapse, fall or damage. If the container of the object is damaged and leaks out, it will endanger the surrounding environment and personal safety. The means of transportation should also be thoroughly cleaned and disinfected, and no other chemicals should remain to avoid adverse reactions with it. During transportation, the speed of the vehicle should not be too fast to prevent damage to the container due to bumps and collisions. Escort personnel must be familiar with its nature and emergency treatment methods, pay close attention on the way, and if there is any abnormality, deal with it immediately.
All of these are important points that cannot be ignored when storing and transporting 1-fluoro-3-isocyanate-2-methylbenzene, so that there is no risk of security.