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1-Fluoro-3-Iodo-2-Methoxybenzene

1-Fluoro-3-Iodo-2-Methoxybenzene

Hongda Chemical

Specifications

HS Code

411200

Chemical Formula C7H6FIO
Molecular Weight 254.02
Appearance Typically a liquid (varies by purity)
Boiling Point Estimated around 220 - 230 °C (approximate, under normal pressure)
Density Estimated around 1.8 - 2.0 g/cm³ (approximate)
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Flash Point Estimated around 90 - 100 °C (approximate)
Refractive Index Estimated around 1.58 - 1.60 (approximate)

As an accredited 1-Fluoro-3-Iodo-2-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - fluoro - 3 - iodo - 2 - methoxybenzene packaged in a sealed, chemical - resistant bottle.
Storage 1 - fluoro - 3 - iodo - 2 - methoxybenzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and strong oxidizing agents. Keep it in a tightly sealed container, preferably made of corrosion - resistant material. Store it in a dedicated chemical storage cabinet to prevent accidental spills and ensure proper segregation from incompatible substances.
Shipping 1 - fluoro - 3 - iodo - 2 - methoxybenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict chemical shipping regulations, ensuring proper labeling, and is transported with care to prevent leakage and maintain safety during transit.
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1-Fluoro-3-Iodo-2-Methoxybenzene 1-Fluoro-3-Iodo-2-Methoxybenzene
General Information
Historical Development
Fu 1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene is also an organic compound. At the beginning of its development, chemists worked hard to explore various synthesis methods. At the beginning, the technology was not mature, and the synthesis road was full of thorns, the yield was low, and the impurities were overgrown.
However, the scientific people were perseverant, and the skills changed over the years. From the crude method in the early days to the fine process in the future, the control of the reaction conditions became more and more precise, and the choice of catalysts became more and more exquisite.
Over the years, the synthesis efficiency of this compound gradually increased, and the purity also greatly improved. Its application in the fields of medicine and materials has also expanded with the advance of technology. What was difficult to make in the past can now be used in many scientific research and industries. It is all thanks to the unremitting research of chemists of all generations that the development and evolution of this compound can shine in the path of science.
Product Overview
1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene is a unique organic compound. Its properties are pure in color, mostly crystalline, and fine in texture. In terms of its structure, fluorine atoms, iodine atoms and methoxy groups on the benzene ring interact according to their positions, giving this compound a different chemical activity.
The preparation method requires multiple delicate reactions. The starting material is carefully selected and pretreated, and the target molecular structure is gradually constructed under specific reaction conditions, or through halogenation, etherification and other steps. The reaction conditions of each step are harsh, and the temperature, pressure and catalyst need to be precisely controlled to improve the purity and yield of the product.
This compound is widely used in the field of organic synthesis. It is often used as a key intermediate, participates in the construction of many complex organic molecules, and makes great contributions to cutting-edge fields such as new drug research and development and materials science. With its unique structure, it can guide the direction of subsequent reactions and assist in the synthesis of novel compounds with specific functions and properties, with broad prospects.
Physical & Chemical Properties
1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene is an organic compound. In terms of its physical properties, it is liquid at room temperature and has a specific melting boiling point. From the perspective of chemical properties, fluorine atoms are electron-absorbing, which can reduce the electron cloud density of the benzene ring and change the activity of the electrophilic substitution reaction of the benzene ring. Although iodine atoms are relatively large and affect the molecular spatial structure, they can participate in a variety of nucleophilic substitution reactions, such as reactions with reagents containing active hydrogen. Methoxy groups have the effect of electron conjugation, which can increase the density of electron clouds in the ortho-para-position of the benzene ring and guide the substituents to specific positions. This compound may have important uses in the field of organic synthesis and can be used as an intermediate to construct complex organic molecular structures through its different substituent reaction properties.
Technical Specifications & Labeling
1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene is an important chemical. Its technical procedures and identification (product parameters) are the key. To make this product, a rigorous method needs to be followed. First take an appropriate amount of starting materials and mix them according to the precise ratio. In the reactor, control the appropriate temperature and pressure to make it chemically change. During the reaction, it is necessary to closely monitor the changes of each parameter to ensure a smooth reaction. After the reaction is completed, the purification process is carried out to obtain pure 1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene. The identification (product parameters) should also be clear, such as purity, impurity content, etc., should be carefully measured and recorded, so that users can use it according to their needs, so as to comply with the essence of this chemical technical specification and identification (product parameters).
Preparation Method
In order to prepare 1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene, it is necessary to clarify its raw materials and production process, reaction steps and catalytic mechanism.
The raw material is selected. When using suitable benzene derivatives, supplemented by reagents containing fluorine, iodine and methoxy groups. In the production process, the method of fine chemical synthesis should be used. The first step is to make the benzene ring react with fluorine-containing reagents under specific conditions to precisely introduce fluorine atoms. This step requires temperature control and time control to achieve the best substitution check point and yield.
The second step is to introduce iodine atoms. With the help of specific catalysts, the reaction of benzene ring and iodine source is catalyzed to optimize the reaction conditions and improve the reaction selectivity. In the final step, add the methoxy group, select the appropriate methoxylation reagent, and complete the reaction under mild conditions.
In the reaction step, each step needs to be carried out in sequence. After each step is completed, it should be purified and separated, and impurities should be removed to facilitate the next step. Catalytic mechanism, each step uses a dedicated catalyst, either a metal catalyst or an organic small molecule catalyst, to accelerate the reaction process, reduce the reaction activation energy, and ensure efficient and highly selective preparation of 1-Fluoro-3-Iodo-2-Methoxybenzene.
Chemical Reactions & Modifications
Taste the wonders of chemistry, it is related to the change of substances, and the effect is miraculous. Now in terms of 1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene, its chemical reaction and modification method are quite interesting.
During chemical reactions, 1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene encounters specific reagents, and the position of fluorine and iodine can be replaced. Fluorine is active, easy to be replaced by other groups, or due to the attack of nucleophiles, resulting in structural changes. Iodine is also non-amphibious, or under suitable conditions, it can be combined with nucleophiles to form a new compound.
As for modification, the change of functional groups can be used to increase its stability or change its activity. Such as changing the chain length of the methoxy group, or adding a group to the benzene ring to adjust the properties of this substance. In this way, it can be used in various fields of medicine and materials to develop its capabilities and open up a new chapter in chemistry for future use.
Synonyms & Product Names
1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene is of great significance in my chemical research. Its synonymous names also refer to each other, just like ancient utensils, although the names are different, they are the same.
Looking at this substance, its synonymous name depends either on its structural characteristics or on its functional effectiveness. All are designed for the convenience of academic colleagues to discuss and communicate. As for the name of the product, it is also used to identify this product in the market, so that the supply and demand can understand its quality and use.
For our researchers, being familiar with its synonymous names and commodity names can accurately find relevant research in the vast literature, and use it correctly during experimental operations. And different names, or contain different research perspectives and application directions, can inspire new ideas and explore new frontiers. Just like in ancient books, a word has multiple meanings, and only when you study it carefully can you understand the true meaning. In this way, the research on 1-Fluoro-3-Iodo-2-Methoxybenzene can go deeper and make achievements step by step.
Safety & Operational Standards
1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene is an important chemical product, and its safety and operating standards are of paramount importance in experiments and production.
All operations involving this substance must be strictly followed by the experimenter. Before starting the operation, it is necessary to know its physical and chemical properties in detail. This substance has specific chemical activities, and knowledge of its characteristics is the cornerstone of safe operation.
In the operating environment, it is necessary to ensure good ventilation. Because the substance or volatile harmful gases, good ventilation can be dispersed in time to prevent it from accumulating in the air and endangering the health of the experimenter. And the operation area should be kept clean and orderly. All kinds of instruments and reagents should be properly placed to facilitate access and avoid the danger caused by accidental collisions.
As for the experimenter's own protection, protective equipment is indispensable. Appropriate experimental clothes should be worn to prevent substances from splashing on the clothes and reduce contact with the body. At the same time, protective gloves must be worn. The material should be able to resist the erosion of the substance and ensure the safety of the hands. Protective glasses are also necessary to prevent substances from splashing into the eyes and causing damage to the eyes.
In terms of specific operation procedures, when taking the substance, the action must be precise and careful. According to the required dosage of the experiment, measure it with an appropriate measuring tool to avoid waste and prevent the trouble of subsequent treatment caused by excessive use. During the reaction process, temperature, pressure and other conditions need to be closely monitored, because the reaction may be sensitive to environmental conditions, slightly deviated, or the reaction may be out of control, resulting in safety accidents.
After the experiment is completed, the remaining 1-Fluoro-3-Iodo-2-Methoxybenzene cannot be discarded at will, and should be disposed of according to specific waste treatment procedures. The instruments used also need to be cleaned in time to remove residual substances for next use.
In this way, following this safety and operation code can ensure the smooth progress of the experiment and ensure the personal safety of the experimenter and the safety of the environment.
Application Area
1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene is a unique chemical substance with unique effects in various application fields.
In the field of pharmaceutical research and development, it can be used as a key intermediate. Due to the special arrangement of fluorine, iodine and methoxy groups in its structure, it can provide a cornerstone for the synthesis of molecules with specific pharmacological activities. Through exquisite chemical reactions, it can be converted into drugs that act on specific targets, or enhance the lipid solubility of drugs, making it easier to penetrate biofilms and improve drug efficacy.
In the field of materials science, this substance also has potential value. Its special functional groups can participate in polymerization reactions to prepare materials with unique optical and electrical properties. For example, optical materials that are sensitive to specific wavelengths of light may be prepared, which can be used in optoelectronic devices such as sensors and light detectors.
Furthermore, in the field of organic synthetic chemistry, 1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene is often an important starting material for chemists to construct complex organic molecules. With the difference in reactivity of different functional groups, complex and diverse organic compounds can be gradually built, contributing to the development of organic synthetic chemistry.
Research & Development
There is a chemical compound named 1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene. As a chemical researcher, I am dedicated to the research and development of this compound.
Looking at the structure of this compound, fluorine, iodine and methoxy are in their respective positions and interact, which is the unique nature of this endowment. In the laboratory, observe its physical and chemical characteristics in detail. Explore its reaction under different conditions, hope to clarify its reaction mechanism, and pave the way for optimizing the synthesis.
After many tests, optimize the synthesis steps to improve the quantity and purity of this product. Also consider its feasibility in industrial production, and think about ways to increase efficiency.
The research on this object is not only an academic exploration, but also a practical application. It can be used in the creation of medicine to add a new way to cure diseases; or it can shine in the field of materials to help the birth of new materials. I will persevere, study this object, promote its development, and hope to benefit the world.
Toxicity Research
Since modern times, chemical refinement has led to the emergence of all kinds of new substances. In the field of chemical engineering, the toxicity of 1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene is quite important.
At the beginning of the research, the molecular structure of the molecule was carefully observed, its chemical bonds were explored, and its possible transformation paths were revealed, which was related to the origin of toxicity. Then, take all kinds of creatures as a test and observe their responses. Take mice as an example and apply this substance to observe changes in their behavior, diet, and organs. If they are seen to move slowly, their diet is sharply reduced, and their organs are damaged, it is proved that they are toxic.
It also examines its migration between environments, and observes whether it is easy to decompose in water, soil and air, and what are the decomposition products. If it is difficult to decompose and accumulates in the environment, it may be a serious problem.
The study of toxicity cannot be done overnight. It must be persevered and investigated carefully to obtain the true meaning, so as to avoid its harm, use it for its benefit, and preserve the peace of life and the environment.
Future Prospects
Wuguanfu 1 - Fluoro - 3 - Iodo - 2 - Methoxybenzene has considerable potential for future development. In today's world, science and technology are changing day by day, and the field of chemical industry is also booming. This compound has a unique structure, or it can make a name for itself in the creation of new materials and the development of medicine.
In the future, it may be possible to use exquisite synthesis methods to increase its output and reduce its cost sharply. In the field of materials, it may become a high-performance insulating and conductive material, contributing to the development of electronic devices. In the forest of medicine, it may be used as a lead compound, which can be carved and modified to become a good medicine for treating diseases and saving people.
In the coming days, with advanced science and technology, everyone will be able to tap the potential of 1-Fluoro-3-Iodo-2-Methoxybenzene to the fullest, open up a new realm for the well-being of mankind, and achieve a magnificent career.
Where to Buy 1-Fluoro-3-Iodo-2-Methoxybenzene in China?
As a trusted 1-Fluoro-3-Iodo-2-Methoxybenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-3-Iodo-2-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1-fluoro-3-iodine-2-methoxybenzene?
The physical properties of 1-% Jiang-3-problem-2-aminobenzoic acid are due to its specific color, taste and shape. Its color is often white or slightly colored crystals, and it is like a collection of natural particles. The taste is particularly bright and the taste is not spicy, pungent or sweet.
Its melting properties are characteristic, ranging from 145 ° C to 147 ° C, and the temperature is so high that this compound is made of solid and liquid, like ice and snow. The properties of this melting are important for the determination and separation of materials.
Furthermore, its solubility is also worthy of attention. 1-% Jiang-3-problem-2-aminobenzoic acid is slightly soluble in water, and can dissolve a small amount in water, just like the stars are scattered in the vast night sky, so it can be completely integrated. However, in ethanol, ether, etc., it has excellent solubility and can be well mixed, just like water and emulsion blend.
In addition, its density is also a certain value, which makes it have a specific surface in diversity and physical operation. Its density is 1.374g/cm ³, reflecting the amount of matter contained in it, and the interaction of other substances. This density characteristic also affects its behavior.
Therefore, the physical properties of 1-% Jiang-3-problem-2-aminobenzoic acid, such as color, taste, shape, melting, solubility and density, form its unique physical appearance, and play an important role in chemical research, engineering, and related fields, helping researchers and users to deeply understand and make good use of this material.
What are the chemical properties of 1-fluoro-3-iodine-2-methoxybenzene?
The powder, algae, and ethyl alcohol all have their own characteristics, and they are used in the world.
The powder is mostly derived from the powder and potato. Its properties gelatinize in contact with water, and the viscosity increases. In food, it is often used to thicken and shape. If you cook the rice, the powder can be added, which can make the liquid thick and the taste smooth. It is also useful for the production of rice, and can melt the combination of water and make the water more suitable.
Algae, taken from seaweed. It has high water content and can be soluble in water. In the food field, it is often used for coagulation and determination. Such as pudding and fruit, algae can make it coagulate but not disperse, and the soil is uniform. In chemical engineering, it is also used to protect the soil, because it can hold water and make the muscle burn.
ethyl gluten, is obtained from the modification of gluten. Its solubility is good, and the degree of influence is small. In the raw material, the viscosity of the raw material can be determined, so that the brush leveling is good, and the flow and uneven thickness will not be produced. In oil exploration, it can be used as a mud additive to increase the quality and buoyancy of the mud, which is beneficial to the benefit of the exploration work.
These three, each of which has its own characteristics, play an important role in many fields, and benefit people.
What is the main use of 1-fluoro-3-iodine-2-methoxybenzene?
1-3-2-aminobenzoic acid has a wide range of main uses. In this field, this is an important raw material for the synthesis of aminobenzoic acid. Due to the specialization of aminobenzoic acid, it can improve the performance of various compounds and assist in the synthesis of specific effects, such as some pain relievers, antibacterial drugs, etc., which can improve human physiology and treat general diseases.
In the dye industry, 1-3-2-aminobenzoic acid also plays a role. It can be used as a synthetic dye to derive color dyes from a series of reverse dyes. This dye has good color fastness and tinting power, and is widely used in dyeing processes such as textiles and leather to give rich color to materials.
Furthermore, it is also useful in chemical industries. Due to its certain biological activity, it can be added to some chemical formulations, such as anti-dyeing products. It can absorb ultraviolet rays in a specific band, providing protection against UV rays, and reducing the damage of UV rays.
In addition, in terms of dyeing, it can be used as a synthetic raw material for some products. The synthesized product can effectively prevent diseases, protect the health of crops, and improve the quality of crops. In addition, 1-3-2-aminobenzoic acid has important uses in various fields, and has greatly expanded in various fields.
What are the synthesis methods of 1-fluoro-3-iodine-2-methoxybenzene?
To prepare 1-alkyne-3-ketone-2-aminoethanol, the following methods can be used:
First, alkyne-ketone and ethanolamine are used as raw materials and prepared by nucleophilic addition reaction. This reaction is in a suitable organic solvent. Under the action of mild temperature and catalyst, the amino group of ethanolamine can launch a nucleophilic attack on the carbonyl group of alkyne-ketone, forming a carbon-nitrogen bond, and then obtain the target product. This process requires attention to the control of reaction conditions to prevent the formation of side reactions, such as over-addition or isomerization reactions.
Second, it is synthesized through a multi-step reaction of alkynes, ketones and ammonia sources. First, alkynes and ketones are reacted under specific conditions to construct intermediates containing alkynyl groups and ketone groups. Then, ammonia sources or reagents that can be converted into amino groups are used to introduce amino ethanol structures through substitution or addition reactions. This path requires careful design of reaction steps to control the selectivity and yield of each step.
Third, use the protective group strategy. Some active groups in the raw material are first protected to prevent unnecessary reactions during the reaction process. After the key reaction steps are completed, the protective group is removed to obtain the target product. For example, alkynyl or ketone groups can be protected first. After the aminoethanol is partially constructed, the protective group can be selectively removed to enable the product to appear. Although this strategy is a little complicated, it can effectively improve the selectivity of the reaction and the purity of the product.
Fourth, the reaction is catalyzed by transition metals. Transition metal catalysts can activate specific chemical bonds to promote the reaction. For example, transition metal catalysts such as palladium and copper are used to catalyze the coupling reaction between alkynes, halogenated ketones and amino ethanol derivatives to efficiently synthesize the target product. This method requires screening suitable catalysts, ligands and reaction conditions to achieve high efficiency and selectivity of the reaction.
What are the precautions for storing and transporting 1-fluoro-3-iodine-2-methoxybenzene?
1-3-wat-2-aminobenzoic acid should pay attention to the following things during storage and transportation:
First, this material should be stored in a cool, dry and well-ventilated place. If the aminobenzoic acid is exposed to high temperature, humidity, or deterioration, it will affect its quality and performance. For example, if it is placed in a hot and humid place, it is prone to moisture and agglomeration, which will reduce its active ingredients and affect subsequent use.
Second, it should be stored separately from oxidants, acids, bases, etc., and must not be mixed. This is because the chemical properties of aminobenzoic acid are active, and contact with the above substances is easy to cause chemical reactions, or cause fire, explosion and other hazards. In case of strong oxidizing agent, or cause violent oxidation reaction, produce hot topic, cause safety accident.
Third, the transportation process must ensure that the packaging is complete and sealed. If the packaging is damaged, aminobenzoic acid or leakage, not only pollute the environment, but also may endanger the health of transportation personnel. For example, its powder leaks into the air, after inhalation, or irritates the respiratory tract, causing discomfort.
Fourth, the transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. In case of leakage and other accidents during transportation, it can be dealt with in time to reduce the harm. If it is not equipped with relevant equipment, once an accident occurs, it will be helpless and the harm will be expanded.
Fifth, when handling, it should be handled lightly to avoid impact and friction. Aminobenzoic acid is subject to strong impact or friction, or causes fire and combustion due to static electricity. If it is rough loading and unloading during handling, the packages will collide with each other or cause danger.