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1-Fluoro-3,4-Dinitrobenzene

1-Fluoro-3,4-Dinitrobenzene

Hongda Chemical

Specifications

HS Code

798466

Chemical Formula C6H3FN2O4
Molar Mass 186.098 g/mol
Appearance Yellow solid
Melting Point 93 - 95 °C
Boiling Point 304.5 °C at 760 mmHg
Density 1.626 g/cm³
Solubility In Water Insoluble
Flash Point 137.9 °C
Vapor Pressure 0.000742 mmHg at 25 °C
Logp 2.04
Refractive Index 1.602

As an accredited 1-Fluoro-3,4-Dinitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - fluoro - 3,4 - dinitrobenzene: Packed in 500g bottles for chemical storage.
Storage 1 - fluoro - 3,4 - dinitrobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition points. It should be kept in a tightly sealed container to prevent exposure to air and moisture. Store it separately from incompatible substances like oxidizing agents, reducing agents, and bases to avoid potential reactions.
Shipping 1 - fluoro - 3,4 - dinitrobenzene is a hazardous chemical. Shipping must follow strict regulations. It should be properly packaged in approved containers, labeled clearly, and transported by carriers licensed for such hazardous substances.
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1-Fluoro-3,4-Dinitrobenzene 1-Fluoro-3,4-Dinitrobenzene
General Information
Historical Development
1 - Fluoro - 3,4 - Dinitrobenzene is also a product of chemistry. At the beginning, all the sages dedicated themselves to the field of chemistry, seeking new things to expand their understanding. In the past, after repeated trials and careful investigation of physical properties, everyone finally obtained this compound.
At the beginning, the synthesis method was still simple, but the yield was not abundant and there were many impurities. After countless spring and autumn, scholars refined their skills and improved the process. Or when more solvents, temperature adjustment, and reaction control were used, the yield gradually increased and the purity became better.
Since ancient times, 1 - Fluoro - 3,4 - Dinitrobenzene has been used in medicine and materials. Its history is a testament to the wisdom and perseverance of scholars, who have made continuous progress, which has led to its great use in the world and become an important chapter in the development of chemistry.
Product Overview
1 - Fluoro - 3,4 - Dinitrobenzene is also a chemical compound. It is an interesting raw material for synthesis. This compound has special properties, and the fluorine atom is set on benzene.
Its properties are special, and the presence of nitro groups makes it active, and it can be substituted and reversed. Fluorine atoms also add their inverse properties. Under specific conditions, they can be synthesized in a special way.
In the field of synthesis, 1 - Fluoro - 3,4 - Dinitrobenzene can be used as a more complex molecule. Due to its high activity, it can be used as an important starting point. By ingeniously introducing different functionalities, many compounds with special purposes can be derived, which may have extraordinary effects in a wide range of fields such as technology and materials.
Physical & Chemical Properties
1 - Fluoro - 3,4 - Dinitrobenzene is also a chemical substance. Its properties are both physical and chemical. In terms of physical properties, under normal conditions, it is either solid or light. Its melting and boiling conditions are fixed, and in the melting process, the boiling conditions are not high or low, which is the main reason for the influence of its properties.
In terms of chemical properties, the presence of fluorine atoms and nitro groups in its molecules makes it active. Nitro has strong absorptive properties, which cause the density of benzene clouds to change, making it easy to generate nuclei. Fluorine atoms have high performance, but because their atoms are half small, they can also be mixed and reversed under specific conditions, which all contribute to the physicochemical properties of 1-Fluoro-3,4-Dinitrobenzene, which are of great significance for chemical research and related engineering.
Technical Specifications & Labeling
1 - Fluoro - 3,4 - Dinitrobenzene, chemical substances are also. Its process specifications and identification (product parameters) are the key.
On the process specification, the synthesis method needs to be rigorous. The ratio of raw materials and the reaction conditions are all fixed. The reaction temperature should be controlled within a certain range. If it is too high, the product will be impure, and if it is too low, the reaction will be slow. And the reaction time needs to be accurately grasped. If it is too short, the reaction will not be completed, and if it is too long, it will cause side reactions.
In terms of identification, the product parameters should be clear. From the appearance color to the purity content, it should be accurately marked. Its appearance or a specific color, the purity must reach a certain proportion, and the impurity content must be within a limited range. In this way, users can use it reasonably according to their process specifications and identification (product parameters) when applying it, in order to achieve the expected effect.
Preparation Method
1 - Fluoro - 3,4 - Dinitrobenzene is an important compound in organic synthesis, and its preparation method is quite critical.
Raw materials and production process: Benzene is used as the initial raw material, and the benzene is co-heated with concentrated nitric acid and concentrated sulfuric acid through nitrification reaction to obtain nitrobenzene. Nitrobenzene is then re-nitrified under specific conditions to introduce a second nitro group to generate 3,4 - dinitrobenzene. Subsequently, a suitable fluorine substitution reagent, such as potassium fluoride, reacts with 3,4 - dinitrobenzene in the presence of a phase transfer catalyst to achieve fluorine substitution to obtain 1 - Fluoro - 3,4 - Dinitrobenzene.
Reaction steps: First, benzene and mixed acid are stirred at a specific temperature range, such as 50-60 ° C, for several hours to complete the first nitrification. After that, the reaction conditions are adjusted for secondary nitrification. During the fluorination reaction, control the reaction temperature, time and material ratio to increase the yield.
Catalytic mechanism: The phase transfer catalyst has a significant effect, which can promote the transfer of fluoride ions from the aqueous phase to the organic phase, enhance the nucleophilicity of fluoride ions, accelerate the reaction rate, and improve the generation efficiency of 1-Fluoro-3,4-Dinitrobenzene.
Chemical Reactions & Modifications
1 - Fluoro - 3,4 - Dinitrobenzene is an important compound in organic synthesis. It is rich in chemical reactions and can be used as an electrophilic reagent to undergo nucleophilic substitution reactions with compounds containing active hydrogen. Under the action of alkali, fluorine atoms are easily replaced by various nucleophilic reagents, showing their reactivity.
However, the properties of this compound can also be improved. Due to the strong electron-absorbing effect of nitro groups, the molecular stability is poor, and it is easy to decompose or undergo side reactions under specific conditions. In order to optimize its performance, its structure can be modified. For example, the introduction of a donator group adjusts the distribution of the electron cloud to enhance the stability; or changes the position of the substituent, which affects the reaction selectivity.
Through the research on the chemical reaction and performance improvement of 1-Fluoro-3,4-Dinitrobenzene, it is expected to expand its application in the field of organic synthesis and obtain more high-value-added products.
Synonyms & Product Names
1 - Fluoro - 3,4 - Dinitrobenzene者,化學之物也。其同義詞與商品名,頗有可究之處。

此化合物,或稱氟代二硝基苯,此乃同義之名。至於商品名,於化學市場之中,亦有諸般稱謂。然其命名,皆依化學之性、結構而定。

夫1 - Fluoro - 3,4 - Dinitrobenzene,其性活潑,於有機合成之域,常為重要之原料。以其氟原子與硝基之特性,能參與諸多化學反應。而其同義詞與商品名之稱,亦隨不同之地域、廠家而有所異。然究其根本,皆指此同一化學物質。化學研究之際,辨明其同義詞與商品名,實為重要之事,可免混淆,利於學術交流與實際應用也。
Safety & Operational Standards
1 - Fluoro - 3,4 - Dinitrobenzene is also a chemical substance. Its safety and operation specifications are related to the smooth flow of the experiment and cannot be ignored.
When taking it, when cleansing your hands and face, wear protective clothing, gloves and goggles to prevent its damage. This thing is toxic and irritating, and it can cause physical injury if you touch it, smell it or eat it. Therefore, when operating, be sure to use it in a well-ventilated place, or in a fume hood, so that the harmful gas can dissipate quickly.
Storage method is also important. It should be placed in a cool and dry place, away from fire and heat sources, and separated from flammable and explosive materials to prevent accidents. The container should be tightly sealed to avoid contact with air and moisture, causing it to deteriorate.
If you accidentally touch it, rinse it with a lot of water quickly, and then seek medical treatment. If it enters the eye, you need to rinse it immediately, and do not rub it, and seek medical attention immediately. If you eat it by mistake, do not induce vomiting, and seek medical treatment immediately.
During operation, the cleaning and drying of the instrument should not be ignored. After using the utensils, wash them quickly to prevent the residual objects from reacting with other objects. The waste of the experiment should not be discarded at will, but should be disposed of in accordance with regulations to protect the environment.
All of these are important for the safety and operation of 1-Fluoro-3,4-Dinitrobenzene, and must be followed to ensure the safety of the experiment and avoid disasters.
Application Area
1 - Fluoro - 3,4 - Dinitrobenzene is a key reagent in chemical synthesis. Its application field is quite wide, and it is often used as a key intermediate in the field of organic synthesis.
Due to the reactivity of fluorine atoms and the strong electron-absorbing properties of nitro groups, this compound can participate in a variety of nucleophilic substitution reactions. Taking drug development as an example, it can be used to react with nucleophiles such as nitrogen and oxygen to construct structural units with specific biological activities, which can help create new drugs.
also has its uses in the field of materials science. Polymer structures can be introduced through specific reactions, giving materials unique properties such as improved thermal stability and chemical stability. For example, by copolymerizing with some polymer monomers, the resulting polymer is more resistant to specific environments, thereby expanding the application scenarios of materials. It can be said that it plays a role that cannot be ignored in many application fields.
Research & Development
1 - Fluoro - 3,4 - Dinitrobenzene is an important compound in organic synthesis. We have been dedicated to its research and development for a long time.
At the beginning, we investigated its synthesis path. After many attempts, benzene was used as the starting material, nitro was introduced through nitration reaction, and then fluoridation was carried out. In this process, the reaction conditions, such as temperature, catalyst type and dosage, were optimized to improve yield and purity.
Its properties cannot be ignored. This compound has high reactivity and can be substituted with a variety of nucleophiles, providing many possibilities for organic synthesis.
As for the application field, in drug synthesis, the use of its special structure to construct key intermediates is expected to develop new drugs.
We continue to study, with more breakthroughs in the research and development of 1 - Fluoro - 3,4 - Dinitrobenzene, adding to the field of chemistry.
Toxicity Research
1 - Fluoro - 3,4 - Dinitrobenzene is also a chemical substance. The remaining elements are toxic substances, and the toxicity of these substances is also paid attention to.
Look at the structure of its molecules, fluorine and dinitro are merged in the benzene ring. Fluorine has strong activity and is easy to react with other substances; nitro groups also have strong oxidation. The combination of the two may make this substance toxic.
If you want to investigate the fact, you should prove it by experiment. Take all kinds of organisms, or insects or mice, and apply this substance to observe its state and signs. If you see its dysfunction, vitality gradually diminishing, or even death, you can know that it is toxic.
And this object enters the body, or interacts with proteins and nucleic acids, causing chaos to its physiological order. Or enters through respiration and skin, damaging the ability of viscera. Therefore, studying its toxicity is beneficial for protection and treatment. In the future, a detailed study will be conducted to clarify the reason for its toxicity, so as to protect the well-being of living beings.
Future Prospects
I have studied the product of 1 - Fluoro - 3,4 - Dinitrobenzene. This product is unique and may be of great use in the chemical industry.
Looking at today's world, technology is changing with each passing day, and the chemical industry is also advancing. 1 - Fluoro - 3,4 - Dinitrobenzene is used in the way of pharmaceutical research and development, or it can open up a new path. Its unique structure can respond to various things, make special drugs, treat all kinds of diseases, and solve the suffering of the world. This is also a hope.
Furthermore, in the field of material innovation, there are also opportunities. Based on this, it may be able to create novel materials with unique properties, which can be used in aerospace, electronics and other industries to help it take off.
Although there may be thorns in the road ahead, I believe that with time and unremitting research, 1-Fluoro-3,4-Dinitrobenzene will be able to bloom its brilliance and contribute to the future development.
Where to Buy 1-Fluoro-3,4-Dinitrobenzene in China?
As a trusted 1-Fluoro-3,4-Dinitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-3,4-Dinitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-fluoro-3,4-dinitrobenzene?
1-pentene-3,4-dicarbonyl benzene is an important organic compound and has a wide range of uses in the field of organic synthesis.
First, it can be used as a key intermediate for the synthesis of complex organic molecules. Because of its special structure, it can use a variety of chemical reactions, such as nucleophilic addition, cyclization, etc., to construct various carbon-carbon bonds and carbon-heteroatomic bonds, and assist in the synthesis of biologically active natural products, drug molecules and functional materials. For example, in the total synthesis of some anti-cancer drugs, 1-pentene-3,4-dicarbonyl benzene is an important intermediate. Through ingeniously designed reaction routes, it participates in the construction of the core skeleton structure of drug molecules, laying the foundation for the development and preparation of drugs.
Second, in the field of materials science, it can be used to prepare high-performance polymer materials. By copolymerizing with other monomers, polymers can impart unique properties, such as improving the thermal stability, mechanical properties and optical properties of polymers. For example, by copolymerizing it with specific olefin monomers, new polymer materials with good thermal stability and optical transparency can be prepared, showing potential application value in optical devices, electronic packaging materials, etc.
Third, in organic catalytic reactions, 1-pentene-3,4-dicarbonylbenzene can function as a ligand or catalyst precursor. Its unique electronic structure and spatial configuration can regulate the activity and selectivity of catalysts, and promote the efficient and highly selective progress of various organic reactions. For example, in some transition metal-catalyzed reactions, the ligands derived from this compound can form stable complexes with metal centers, significantly improving the catalytic efficiency and product selectivity of the reaction, providing more effective methods and strategies for organic synthesis chemistry.
What are the physical properties of 1-fluoro-3,4-dinitrobenzene?
1-% E6% B0% 9F-3, 4-%E4%BA%8C%E7%A1%9D%E5%9F%BA%E8%8B%AF%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%E4%B8%8B%E8%AF%B4%E4%B8%80%E4%B8%8B%EF%BC%9A
1.75% Ethanol Solution Properties
1 -% E6% B0% 9F is 75% ethanol solution, this solution has good solubility and can dissolve a variety of organic substances, such as some resins, pigments, etc. Because of the coexistence of hydroxyl and hydrocarbon groups in its molecular structure, it is both hydrophilic and lipophilic, and can be miscible with water in any ratio. And volatile, it will take away heat when dissipated, and it has a cool feeling. It is often used for skin surface disinfection, which can dehydrate bacterial proteins, denature and coagulate, so as to achieve the purpose of sterilization.
2. Properties of 3,4-dihydroxybenzoic acid
3,4-dihydroxybenzoic acid, the appearance is mostly white to light yellow crystalline powder. Its molecule contains carboxyl groups and two hydroxyl groups, which are acidic to a certain extent and can neutralize with bases to form corresponding salts. Due to the presence of hydroxyl groups, it is prone to esterification and reacts with alcohols under certain conditions to form esters. At the same time, the substance has a certain solubility in water, and due to the existence of a phenyl ring and a hydroxyl conjugate system, it has certain oxidation resistance and can be used as an antioxidant in some fields. In addition, the phenolic hydroxyl group in its structure makes it capable of complexing with certain metal ions and can form stable complexes.
What are the chemical properties of 1-fluoro-3,4-dinitrobenzene?
1-Hydrocarbon-3,4-dicarboxylnaphthalene is an organic compound with unique chemical properties. In this compound, the hydrocarbon group is the basic structure, which endows it with a certain fat solubility and relative stability, while the introduction of 3,4-dicarboxyl groups significantly changes its overall chemical properties.
As far as acidity is concerned, the carboxyl group (-COOH) brings its acidic properties. In a suitable solvent environment, the carboxyl group can dissociate and release hydrogen ions (H <), exhibiting the typical behavior of acidic substances, which can neutralize with bases to form corresponding carboxylate and water. For example, when reacted with sodium hydroxide (NaOH), a sodium salt of 1-hydrocarbon-3,4-dicarboxylnaphthalene is formed with water.
Its hydrophilicity is increased by the presence of carboxyl groups. Carboxyl groups are hydrophilic groups. Compared with simple hydrocarbon compounds, the solubility of 1-hydrocarbon-3,4-dicarboxylnaphthalene in water is increased due to the presence of carboxyl groups. However, due to the influence of hydrocarbon groups, its water solubility is still limited.
From the perspective of reactivity, carboxyl groups can participate in a variety of organic reactions. For example, under appropriate catalysts and reaction conditions, carboxyl groups can be esterified with alcohols to form esters. This reaction can not only be used to synthesize ester products with specific functions, but also to construct more complex compound structures in the field of organic synthesis.
In addition, the structure of the naphthalene ring in this compound will also affect its chemical properties. The naphthalene ring has certain aromaticity and is relatively stable, but under specific conditions, such as the action of strong oxidants, the naphthalene ring may undergo oxidation reaction, resulting in structural changes, which in turn affect the properties of the whole compound.
To sum up, 1-hydrocarbon-3,4-dicarboxylnaphthalene exhibits unique and diverse chemical properties due to the interaction between the functional groups contained in it and the basic structure, which has important research and application value in the field of organic chemistry.
What are the synthesis methods of 1-fluoro-3,4-dinitrobenzene?
To prepare 1-hydrocarbon-3,4-dicarboxylnaphthalene, the following methods can be used:
First, the naphthalene is used as the starting point, and the acyl group is first introduced through Fu-gram acylation. Naphthalene and acyl halide can obtain 1-acyl naphthalene under the catalysis of Lewis acid such as anhydrous aluminum trichloride. This step requires mild reaction conditions and temperature control in an appropriate range to avoid polyacylation. After oxidation of 1-acyl naphthalene, the acyl group is converted to a carboxyl group. Common oxidants such as potassium permanganate, potassium dichromate and other strong oxidants can achieve this conversion under appropriate solvents and reaction conditions to obtain 1-carboxylnaphthalene. Next, the 1-carboxylated naphthalene is acylated again, an acyl group is introduced at the 3rd position, and then oxidized to obtain 1-hydrocarbon-3,4-dicarboxylnaphthalene.
Second, the aromatic hydrocarbon can be substituted appropriately. First, the naphthalene group is introduced at a specific position of the aromatic hydrocarbon through electrophilic substitution, and then the naphthalene ring is modified in a series. For example, the aromatic hydrocarbon containing a suitable substituent is coupled with a naphthalene halide under metal catalysis to obtain a naphthalene-containing aromatic hydrocarbon. After the carboxyl group is introduced into the naphthalene ring, the naphthalene ring can be halogenated first, and then cyanylated and hydrolyzed to obtain a carboxyl group. After ingenious design steps
Third, natural products with similar structures can also be considered as raw materials. After some natural products are separated and purified, the target products are obtained by chemical modification. For natural products containing naphthalene rings, the substituents are selectively modified by chemical means, and the carboxyl groups are gradually introduced. This process requires the use of the unique structure and activity check point of natural products, and the transformation is achieved under mild reaction conditions to ensure both yield and product purity. However, such methods are limited by the source and content of natural products.
What are the precautions for storing and transporting 1-fluoro-3,4-dinitrobenzene?
When storing and transporting 1-alkane-3,4-dicarboxylnaphthalene, the following things should be paid attention to:
First, because of its active chemical properties, when storing, be sure to choose a dry, cool and well-ventilated place. Moisture can easily cause it to deteriorate, and high temperature may cause chemical reactions, so the control of temperature and humidity is essential. It is advisable to store it in a closed container to prevent contact with oxygen, water vapor and other substances in the air.
Second, when transporting, extra caution is also required. The packaging must be solid and reliable to prevent vibration and collision from causing damage to the container and causing material leakage. Appropriate means of transportation and protective means should be selected in accordance with relevant regulations. Transportation personnel should be familiar with its characteristics and emergency treatment methods. In case of leakage and other accidents, they can be dealt with quickly and properly.
Third, 1-alkane-3,4-dicarboxylnaphthalene may be toxic and corrosive to a certain extent. During storage and transportation, staff should strictly follow safety operating procedures and wear complete protective equipment, such as protective clothing, gloves, goggles, etc., to avoid physical contact. In case of inadvertent contact, they should be treated immediately according to the correct first aid methods and seek medical attention as soon as possible.
Fourth, storage areas and transportation vehicles should be kept away from fire sources, heat sources, and all kinds of flammable and explosive objects. Due to its chemical properties, in case of open flames, hot topics or the risk of combustion and explosion. And it should be stored and transported separately from oxidants, acids, alkalis and other substances to avoid dangerous chemical reactions caused by mixed storage and transportation.
Fifth, whether it is a storage place or a transportation link, it should be set up with prominent warning signs to remind personnel to pay attention to safety. And equipped with corresponding emergency rescue equipment and equipment, such as fire extinguishers, leakage emergency treatment tools, etc., in order to respond in time in emergencies and minimize hazards.