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1-Fluoro-2-(Trichloromethyl)Benzene

1-Fluoro-2-(Trichloromethyl)Benzene

Hongda Chemical

Specifications

HS Code

131499

Chemical Formula C7H4Cl3F
Molecular Weight 213.46
Appearance Colorless to light yellow liquid
Boiling Point Around 205 - 207 °C
Density Approx. 1.49 g/cm³
Vapor Pressure Low, but specific value depends on temperature
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
Flash Point Around 82 °C
Odor Characteristic aromatic odor

As an accredited 1-Fluoro-2-(Trichloromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - fluoro - 2 - (trichloromethyl)benzene packaged in 500 - mL glass bottles.
Storage 1 - fluoro - 2 - (trichloromethyl)benzene should be stored in a cool, well - ventilated area away from heat sources and open flames. Keep it in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals. Ensure the storage area has proper spill - containment measures to handle any potential leaks safely.
Shipping 1 - fluoro - 2 - (trichloromethyl)benzene is shipped in accordance with strict chemical transport regulations. It's packaged in specialized containers to prevent leakage, and transported by carriers trained in handling hazardous chemicals.
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1-Fluoro-2-(Trichloromethyl)Benzene 1-Fluoro-2-(Trichloromethyl)Benzene
General Information
Historical Development
1 - Fluoro - 2 - (Trichloromethyl) Benzene is also an organic compound. In the past, chemists studied the properties and synthesis of various halogenated aromatic hydrocarbons. At the beginning, only simple halogenated benzene was known. With the improvement of scientific research, the exploration of complex substituent combinations gradually emerged.
At that time, many scholars tried different reaction paths to prepare such compounds. After repeated experiments, under specific reaction conditions, fluorine atoms and trichloromethyl were introduced into benzene as a group to obtain this compound. When it was first obtained, it was only a laboratory product. With the improvement of technology, the synthesis efficiency gradually increased. Since its inception, it has emerged in the fields of organic synthesis, materials science, etc., laying the foundation for subsequent related research and applications, and opening a new chapter.
Product Overview
1 - Fluoro - 2 - (Trichloromethyl) Benzene is a unique chemical substance. Its color is pure and transparent, liquid-like, and has a special smell.
The preparation of this substance requires a precise and strict method and an appropriate agent. In the reactor, the reactants are entered in sequence, the temperature is controlled, and the pressure is carefully controlled, so that the process should proceed.
It is active and has a wide range of uses in the field of organic synthesis. It can be used as an intermediate to produce a variety of fine chemicals. Or involved in the research of drugs, the manufacture of materials and other industries.
When using it, you must also be careful. Due to its certain toxicity and corrosiveness, when operating, it is necessary to abide by regulations, prepare protective equipment, and ensure safety in order to make good use of this chemical treasure to promote the advancement of science and technology and the prosperity of industry.
Physical & Chemical Properties
1 - Fluoro - 2 - (Trichloromethyl) Benzene is an organic compound. Its physical and chemical properties are related to many aspects. In terms of physical properties, it has a specific color, taste and form. It is liquid at room temperature and has a certain density and boiling point, which is related to the transformation of its phase state.
Discusses chemical properties. In its molecular structure, the presence of fluorine atoms and trichloromethyl gives it unique reactivity. Fluorine atoms have strong electronegativity, which can affect the distribution of electron clouds in molecules, so that the compound exhibits special performance in reactions such as nucleophilic substitution. Trichloromethyl also has an important impact on its chemical behavior, or can participate in various organic reactions, such as the interaction with nucleophilic reagents. The physicochemical properties of this compound are of great significance in the fields of organic synthesis and materials science, laying the foundation for related research and applications.
Technical Specifications & Labeling
1 - Fluoro - 2 - (Trichloromethyl) Benzene is an important chemical product. Its technical specifications and identification (product parameters) are crucial. The technical specifications of this product are related to purity, impurity content, etc. When the purity reaches a very high standard, impurities need to be strictly controlled to ensure its high quality. In terms of identification, product parameters should be clear and clear, such as molecular weight, chemical structure, etc., all need to be accurately marked. This chemical is widely used in industrial production, scientific research experiments and other fields. However, because of its certain chemical activity, strict requirements for its technical specifications and labeling are the foundation for ensuring its safe and effective application, and it is also a necessary condition for promoting the stable development of related industries.
Preparation Method
The method of making 1 - Fluoro - 2 - (Trichloromethyl) Benzene is very important, which is related to the raw materials and production process, reaction steps and catalytic mechanism.
The selection of raw materials should be pure. The benzene-based, coupled with fluorine-containing and chlorine-containing agents, requires quasi-quality. The production process first reacts benzene with chlorine-containing reagents according to a specific method to obtain chlorobenzene-containing derivatives. Then, fluorine is introduced, and this step requires temperature control and pressure control, and the reaction conditions are observed.
The first step is chlorination, which gradually adds chlorine atoms on the benzene ring, during which the reaction process is observed and adjusted in a timely manner. Second-step fluorination, through fine operation, the fluorine atoms are precisely replaced to achieve the desired structure.
Catalytic mechanism, the appropriate catalyst is selected to promote the reaction rate and yield. The activity and selectivity of the catalyst need to be appropriate, and it is easy to separate and recover after the reaction, and the reuse can also maintain its performance. In this way, 1-Fluoro-2 - (Trichloromethyl) Benzene is prepared, and the quality may be optimized.
Chemical Reactions & Modifications
To taste the wonders of chemical industry, it is essential to change substances, react and modify them. Today there is 1 - Fluoro - 2 - (Trichloromethyl) Benzene, and its chemical reaction is worth exploring.
To investigate its reaction, its structural properties need to be clarified. In this compound, the position of the fluorine atom and trichloromethyl affects the reactivity. Fluoride has strong electronegativity, which changes the electron cloud density of the benzene ring, and ortho-trichloromethyl also has an induction effect.
In many reactions, its properties can be exploited. Or react with nucleophiles, fluorine atoms can be replaced and new functional groups can be introduced to achieve modification. This process requires control of the reaction conditions, and temperature and solvent are all affected. After modification, the product has variable properties, or has higher stability, or has special chemical activity, and has potential uses in materials, medicine and other fields.
Chemical research, specializing in exploring material changes, the reaction and modification of 1-Fluoro-2 - (Trichloromethyl) Benzene is also the cornerstone of chemical progress.
Synonyms & Product Names
1 - Fluoro - 2 - (Trichloromethyl) Benzene, its trade name is the same as that of chemical research. In chemical texts, its name often exists. Or because of its characteristics, it is the same as that of its manufacture, and it also has a derivative trade name due to its commercial use and production.
In the past, it is the same as that of benzene, because of the location of the fluorine atom trichloromethyl, or it has the name of orientation and basis. And the trade names have their own appearance due to the positioning of different merchants and the needs of the market. This all reflects the fact that chemical substances are not used in commercial research and circulation, and their names are different. Exploring the same product name is conducive to the understanding of the characteristics of the product, and it is also convenient for the business community to clarify its use. It is of great significance for research and development.
Safety & Operational Standards
1 - Fluoro - 2 - (Trichloromethyl) Benzene is also a chemical substance. It is of paramount importance for the safe operation of this chemical substance.
All researchers of this substance must first understand its properties. This substance has certain chemical activity, and if it is not handled carelessly, it may cause danger. Therefore, the operation of this substance must follow the strict procedures.
The first safety precaution. Those who operate this substance should wear appropriate protective clothing, such as clothing that is resistant to chemical corrosion, and wear anti-corrosion gloves, which can block the penetration of this substance. The face should have eyes to prevent the appearance of objects and eyes.
Furthermore, the operation environment should be well connected. This substance or harmful substances can be quickly dispersed, so as not to gather in the room and endanger the person. Where the operation is carried out, there should be no eye wash and safety shower to prevent damage. If you accidentally wash the skin or eyes, immediately wash with a lot of water, and ask for it as soon as possible.
The operation should not be ignored. When using this substance, use the appropriate equipment, and be careful to avoid overflow. When mixing other chemicals, you must check the reaction according to the established order and proportion. After the reaction is completed, the remaining substances and liquids should not be properly handled according to the phase, so as not to dye the environment.
Therefore, the safe operation of 1 - Fluoro - 2 - (Trichloromethyl) Benzene is essential to ensure the safety and safety of researchers and should not be slack.
Application Area
1 - Fluoro - 2 - (Trichloromethyl) Benzene is a unique chemical substance. It has a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize a variety of specific drugs, which are quite effective in healing various diseases. In the field of materials science, special materials made from this raw material have unique physical and chemical properties, or can be used to make components of high-end electronic products to improve their performance. In the field of organic synthesis, it is also an important cornerstone. It can be derived from a variety of chemical reactions to generate a variety of novel compounds, contributing to the development of organic synthetic chemistry. With its unique chemical structure, this substance shines in various application fields and contributes to the progress and practical application of related disciplines.
Research & Development
I am dedicated to the research of 1 - Fluoro - 2 - (Trichloromethyl) Benzene. This compound has unique properties and has great potential in many fields. At the beginning, I explored its synthesis path, but encountered many obstacles. The selection of raw materials and the control of reaction conditions all need to be carefully considered.
After repeated experiments, a feasible method was finally found. The yield did not meet expectations, and I dedicated myself to research and improve the process. In the selection of catalysts, the preparation of temperature and pressure, all thought carefully.
With the deepening of research, it was found that it may be useful in the fields of materials science and medicine. Then I expanded the research scope and collaborated with colleagues, hoping to translate this research result into practical application and promote the development of related fields. I firmly believe that in time, 1 - Fluoro - 2 - (Trichloromethyl) Benzene will be able to shine and bring new breakthroughs to the industry.
Toxicity Research
In recent years, I have been paying attention to chemical substances, especially 1 - Fluoro - 2 - (Trichloromethyl) Benzene. The toxicity of this substance is related to the health of everyone and the tranquility of the environment, so it cannot be studied carefully.
I have checked the books more and more, looking at the history of its experiments, and examining its behavior in the environment. 1 - Fluoro - 2 - (Trichloromethyl) Benzene is toxic, entering the body of living things, or disturbing their physiological order. Looking at the tests of animals, it can cause damage to the organs, and it also has adverse effects on the nervous system.
Thinking about it in the environment, or it is difficult to die for a long time, accumulating in water and soil. Biological ingestion, along the food chain, is increasingly harmful. Therefore, if you want to reduce its harm, you must control its use and develop harmless substitutes. In the future, people can live in a comfortable environment, away from the disturbance of poisons.
Future Prospects
When I look at this world, science and technology are changing day by day, and chemical things have infinite possibilities. 1 - Fluoro - 2 - (Trichloromethyl) Benzene, although this chemical is only one thing now, its future prospects are really imaginative.
This thing may shine in the field of materials. It can help develop new types of polymeric materials, which are tough and have specific protective functions, or can be used in aerospace and deep-sea equipment to resist external erosion. In the road of medicine, it is also possible. With its unique structure, it may be able to form new drug molecules to overcome difficult diseases and save thousands of lives.
And with the deepening of research, the synthesis method may become more subtle, the cost will gradually decrease, and the output will gradually increase. At that time, this product will be widely used in the world, adding wings to industry, adding color to people's livelihood, and leading future development. It is like a star shining in the sky, illuminating the unknown. This is the vision of our generation of chemical researchers for their future.
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Frequently Asked Questions

As a leading 1-Fluoro-2-(Trichloromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1-fluoro-2- (trichloromethyl) benzene?
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This substance is a chemically synthesized organic compound, and its physical properties are quite characteristic. Under normal temperature and pressure, its state is usually a liquid state, just like a flowing nectar, with a relatively uniform texture, as if it were one.
Looking at its color, it usually shows a colorless and transparent shape, just like clear water, without the slightest variegation, giving people a sense of purity. Smell its smell, with a unique fragrance, although not rich and pungent, but also clear and distinguishable, unique.
Its density is slightly different from that of common water, and the specific value varies depending on the conditions of accurate measurement, but it is roughly different. In terms of solubility, in organic solvents, such as ethanol, ether, etc., it exhibits good solubility and can be mutually soluble with it, just like water emulsion blends; in water, its solubility is relatively limited, just like oil floating in water, it is difficult to completely melt.
Furthermore, the boiling point of this substance is also one of the important physical properties. Under a specific pressure environment, its boiling point can be determined to obtain a specific value, which determines the critical temperature at which it changes from liquid to gaseous during heating. When heated, when the temperature gradually rises to the boiling point, it can be seen as a steam of evaporation, turning into a gaseous state and rising.
In terms of melting point, under low temperature conditions, it will gradually solidify from liquid to solid state, and this transition temperature is the melting point. Below the melting point, it will exist stably in the solid state and become hard, like the condensation of ice. These physical properties together constitute the characteristics that distinguish 1-%E6%B0%9F-2-%28%E4%B8%89%E6%B0%AF%E7%94%B2%E5%9F%BA%29%E8%8B%AF from others, and are of key significance in many fields such as chemical research and industrial applications.
What are the chemical properties of 1-fluoro-2- (trichloromethyl) benzene?
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This substance has certain chemical activity. In its molecular structure, the combination of 1-hydrocarbon group and 2 - (trifluoromethyl) phenyl group causes it to exhibit unique properties.
In terms of physical properties, it is often liquid or solid, depending on the specific substituent and environmental conditions. Its melting point and boiling point are affected by intermolecular forces and structures. If the hydrocarbon group is longer, the intermolecular van der Waals force is enhanced, and the melting point and boiling point may increase; the existence of trifluoromethyl has a significant impact on molecular polarity due to its strong electronegativity.
Chemically, trifluoromethyl has strong electron absorption, which can reduce the electron cloud density of the benzene ring, reduce the electrophilic substitution activity on the benzene ring, and the reaction check point may change. For example, when electrophilic substitution is more inclined to meta-substitution. The hydrocarbyl moiety, if it is an unsaturated hydrocarbon group, can undergo an addition reaction, such as with halogens, hydrogen halides and other reagents, depending on the unsaturation of the hydrocarbyl group and the reaction conditions. If the hydrocarbyl group contains α-hydrogen, the substitution reaction of α-hydrogen can occur under appropriate conditions.
In addition, this substance has unique stability to certain reagents. Due to the strong electron-absorbing effect of trifluoromethyl, it has high stability to some nucleophiles. However, under strong oxidation or reduction conditions, the molecular structure may be damaged, and oxidation and reduction reactions occur. The specific reaction path and product depend on the reaction conditions and the type of reagents used. In short, 1-hydrocarbon-2- (trifluoromethyl) benzene has rich chemical properties and has important applications in organic synthesis and other fields. Reactions need to be reasonably designed according to their characteristics to achieve the expected synthesis goals.
What are the main applications of 1-fluoro-2- (trichloromethyl) benzene?
1-%E6%B0%9F-2-%28%E4%B8%89%E6%B0%AF%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E8%80%85, is an extraordinary medicine, in many areas have significant use.
In the field of medical Tao, its effect is very great. It can treat all kinds of diseases, such as poor qi and blood, and blocked meridians. If the human body loses qi and blood, and the meridians are blocked, the pain breeds. This medicine can promote blood circulation and remove blood stasis, make the flow of qi and blood smooth, and the meridians return to Tongtai, and many painful diseases can be relieved. And for those with weak organs and declining functions, it also has the power of tonics, which can enhance the power of the organs, improve the body's ability to resist disease and evil, and help patients recover as soon as possible.
In the path of health preservation, it is also indispensable. People today often suffer from physical deficiency due to hard work and impermanent living. 1-%E6%B0%9F-2-%28%E4%B8%89%E6%B0%AF%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E8%80%85 can reconcile yin and yang, balance the righteous qi in the body, and nourish essence, qi, and spirit. Daily use of it can make people feel healthy and energetic, delay the process of aging, make the body strong, and prolong life.
For martial arts practitioners, this medicine has outstanding effect. Those who practice martial arts often need to strengthen their physique and improve their internal strength. This medicine can help them get through the two veins of Ren and Governor, gather qi and blood around the body, and enhance their internal strength. When practicing, taking this medicine can speed up the growth of skills, and after being injured, they can quickly restore vitality, promote the healing of injuries, and enable martial artists to return to the path of practice faster and improve their martial arts realm.
In the realm of cultivating immortal magic, 1-%E6%B0%9F-2-%28%E4%B8%89%E6%B0%AF%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E8%80%85 also has extraordinary uses. It can purify the spiritual energy of the cultivator, make it absorb the spiritual energy of heaven and earth more smoothly, and improve the efficiency of cultivation. Help cultivators break through the bottleneck, enter a higher level of cultivation, comprehend the truth of heaven and earth, and get a glimpse of the door of immortality.
In general, 1-%E6%B0%9F-2-%28%E4%B8%89%E6%B0%AF%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E8%80%85 in many fields such as medical, health care, martial arts, and immortal cultivation, it has shown its unique and important value, which is cherished by everyone.
What is the preparation method of 1-fluoro-2- (trichloromethyl) benzene?
To prepare a preparation of 1-ether-2- (trifluoromethyl) naphthalene, the method is as follows:
First take the naphthalene as the base, and introduce a halogen atom at a specific position in the naphthalene ring by halogenation. This halogenation process requires careful temperature control, selection of suitable solvents and halogenating reagents. Usually bromine or chlorine is used as a halogenating agent, in an inert solvent such as dichloromethane, accompanied by a suitable catalyst, such as iron powder or iron salt, to react with the halogenating agent to obtain halogenated naphthalene.
Second, the prepared halogenated naphthalene is nucleophilic substitution with a reagent containing trifluoromethyl. This reagent containing trifluoromethyl can be selected from Grignard reagents such as trifluoromethyl magnesium halide. In an anhydrous and oxygen-free environment, using tetrahydrofuran as a solvent, halogenated naphthalenes are slowly dropped into the solution containing Grignard reagents and the reaction is stirred. The key to this step is to maintain the anhydrous and oxygen-free reaction system, because both water and oxygen can cause the decomposition of Grignard reagents, thus affecting the reaction process.
Then, it is etherified to form the target product. Take the naphthalene derivative containing trifluoromethyl obtained from the above reaction, and the corresponding alcohol or phenol under alkaline conditions, with an appropriate base, such as potassium carbonate, etc., in a polar solvent such as N, N-dimethylformamide, heat and stir the Through this etherification step, the preparation of 1-ether-2- (trifluoromethyl) naphthalene was achieved.
After the reaction is completed, it needs to be separated and purified. The solvent and low boiling point impurities in the reaction system can be removed by vacuum distillation. Then column chromatography was used to select suitable silica gel as the stationary phase, and the mixed liquid of petroleum ether and ethyl acetate in a certain proportion was used as the mobile phase to separate the products, so that the pure 1-ether-2- (trifluoromethyl) naphthalene was obtained.
What are the precautions for storing and transporting 1-fluoro-2- (trichloromethyl) benzene?
1-%E6%B0%9F-2-%28%E4%B8%89%E6%B0%AF%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E5%9C%A8%E5%82%A8%E5%AD%98%E5%92%8C%E8%BF%90%E8%BE%93%E8%BF%87%E7%A8%8B%E4%B8%AD%E5%BF%85%E9%A1%BB%E6%B3%A8%E6%84%8F%E4%B8%8B%E5%88%97%E4%BA%8B%E9%A1%B9:
The first one is to hide the utensils, and you must choose a good place. This medicine should be placed in a cool, dry and well-ventilated place, away from direct sunlight, to cover the intensity of sunlight, or cause its properties to change. It should also be kept away from fire and heat sources to prevent accidents.
Second, the reservoir should be selected carefully. It is better to use glass or ceramic utensils, because their material is stable and does not violate the medicine. If using plastic utensils, check whether they are resistant to corrosion to prevent the medicine from corroding with the utensils and damaging their medicinal properties.
Furthermore, during transportation, make sure to be stable. The bumps and collisions of the road can damage its quality. It is better to use soft cushions to slow down its vibration. And the temperature and humidity of transportation should also be paid attention to. If the temperature is high, it will be easy to change, and if the humidity is heavy, it will be easy to get damp, which is not conducive to the storage of medicine.
Moreover, the label should not be ignored. On the reservoir, the name, nature, usage and attention must be written to avoid misuse.
Compound, separate from other things. Do not store and transport with odorous things. The drug is sensitive, odor or disturb its quality, and its effect will be damaged.
All these are related to 1-%E6%B0%9F-2-%28%E4%B8%89%E6%B0%AF%E7%94%B2%E5%9F%BA%29%E8%8B%AF%E5%9C%A8%E5%82%A8%E5%AD%98%E5%92%8C%E8%BF%90%E8%BE%93%E8%BF%87%E7%A8%8B%E4%B8%AD%E4%B9%8B%E8%B4%A8 and must not be taken lightly.