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1-Fluoro-2-Methylbenzene

1-Fluoro-2-Methylbenzene

Hongda Chemical

Specifications

HS Code

311967

Chemical Formula C7H7F
Molar Mass 110.13 g/mol
Appearance Colorless liquid
Odor Aromatic odor
Density 0.991 g/cm³
Boiling Point 116 - 117 °C
Melting Point -57.2 °C
Flash Point 13 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Vapor Pressure 1.9 kPa at 20 °C
Refractive Index 1.477

As an accredited 1-Fluoro-2-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - fluoro - 2 - methylbenzene in 500 - mL glass bottles, tightly sealed for chemical storage.
Storage 1 - fluoro - 2 - methylbenzene should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames due to its flammability risk. It should be kept in a tightly sealed container, preferably made of materials resistant to corrosion. Store it separately from oxidizing agents and incompatible substances to prevent potential chemical reactions.
Shipping 1 - fluoro - 2 - methylbenzene is shipped in sealed, corrosion - resistant containers. These are carefully packed in sturdy outer boxes with appropriate cushioning. Shipments follow strict hazardous material regulations to ensure safe transit.
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1-Fluoro-2-Methylbenzene 1-Fluoro-2-Methylbenzene
General Information
Historical Development
1 - Fluoro - 2 - Methylbenzene is also an organic compound. Its historical development has its own roots. In the past, the chemists studied the way of organic synthesis diligently. At the beginning, they explored various reaction paths to obtain this compound. After many attempts, either by halogenation or by substitution, they gradually achieved success.
Early preparation, the methods are complicated and the yield is not abundant. However, the ambition of chemists has not changed, and they strive for excellence. With the passage of time, the technology has been perfected day by day, and new synthesis strategies have emerged. The reaction conditions are milder and the yield has to be improved.
From the difficult exploration in the past to the maturity of today's synthetic methods, the development of 1-Fluoro-2-Methylbenzene is a brilliant page in the history of chemistry, witnessing the unremitting pursuit of chemists and the crystallization of wisdom.
Product Overview
1 - Fluoro - 2 - Methylbenzene is an organic compound. It is a colorless liquid with a special odor. This compound is composed of a fluorine atom and dimethyl benzene. Its physical properties are particularly important, the boiling point is about a certain value, and the density is also specific. In terms of chemical properties, it has unique reactivity because it contains fluorine atoms and methyl groups. It can participate in a variety of chemical reactions, such as electrophilic substitution reactions. It has a wide range of uses in the field of organic synthesis and can be used as an intermediate to prepare many complex organic compounds. In industry, it can be prepared through specific chemical processes. From its structure and properties, it can be seen that it is of considerable value in chemical research and industrial production, and can contribute to the development of organic chemistry and the progress of related industries.
Physical & Chemical Properties
1 - Fluoro - 2 - Methylbenzene is an organic compound. It has unique physical and chemical properties. Looking at its physical properties, at room temperature, it is a colorless liquid with a specific aroma. Its boiling point is about a certain value, which is determined by the intermolecular force. And its density is also a specific value, lighter than water, so it floats on water.
As for the chemical properties, because of its fluorine and methyl group, fluorine atoms have strong electronegativity, causing the density of benzene ring electron clouds to change, so that the compound exhibits unique activity in the electrophilic substitution reaction. Methyl is the power supply group, which also affects the check point and rate of the reaction. It can react with many reagents. If it encounters a halogenating agent, it can initiate a halogenation reaction; when it encounters a nitrifying agent, it has a nitrification change. This is due to the interaction between atoms and groups in its structure, which makes it have an important position and application in the field of organic synthesis.
Technical Specifications & Labeling
1 - Fluoro - 2 - Methylbenzene is an organic compound, and its preparation process and standards are very critical.
The preparation method requires precise steps and appropriate raw materials. Often a specific chemical reaction is used, and it is strictly operated according to the chemical principle. Reaction conditions such as temperature, pressure, catalyst, etc., must be finely regulated. If the temperature is too high or too low, the reaction can be biased, affecting the purity and yield of the product.
Product standards are about their quality. The purity must reach a certain level, and the impurity content should be strictly controlled. Physical properties such as appearance and odor are also considered. After rigorous testing methods, such as chromatographic analysis, spectroscopic determination, etc., to clarify its composition and structure, to ensure that it meets quality specifications. In this way, the high-quality 1-Fluoro-2-Methylbenzene products are used in the chemical industry and other fields.
Preparation Method
1 - Fluoro-2 - Methylbenzene is an organic compound. The preparation method involves raw materials, production processes, reaction steps and catalytic mechanisms.
The raw materials can be used with o-toluidine, sodium nitrite, hydrofluoric acid, etc. First, the o-toluidine and sodium nitrite react in an acidic environment to form diazonium salts. This is a key step. The diazonium salt has high activity and lays the foundation for subsequent reactions.
Subsequently, the diazonium salt reacts with hydrofluoric acid, and the diazonium group is replaced by a fluorine atom to obtain 1 - Fluoro-2 - Methylbenzene. This reaction requires a suitable temperature and pH to ensure a smooth reaction.
In terms of catalytic mechanism, an appropriate amount of catalyst can be added to accelerate the reaction process and increase the yield. The catalyst can reduce the activation energy of the reaction and make it easier for the reactants to be converted into products.
The whole preparation process, each step is closely linked, and the reaction conditions need to be precisely controlled to obtain 1-Fluoro-2-Methylbenzene efficiently.
Chemical Reactions & Modifications
1 - Fluoro - 2 - Methylbenzene is also an organic compound. In the field of chemistry, its reaction and modification are worth studying.
In the past, to obtain this compound, there are many complicated steps, and the yield is not good. Looking at its reaction, it is often done by the method of halogenated aromatics, but side reactions occur frequently, resulting in impure products.
At present, chemists are trying their best to find a good way to modify it. There are those who introduce new catalysts to make the reaction conditions mild and the selectivity is greatly increased. There are also those who optimize the reaction path to avoid cumbersome processes and increase the yield.
After many investigations, the preparation and application of 1-Fluoro-2-Methylbenzene have made progress. Chemists are still working tirelessly to make more breakthroughs in their reactions and modifications, contributing to the chemical industry and promoting its vigorous development.
Synonyms & Product Names
1 - Fluoro - 2 - Methylbenzene, also known as o-fluorotoluene. In the field of chemical industry, synonyms are common. O-fluorotoluene has a wide range of industrial uses, but its names vary. It is also known as 2 - methyl fluorobenzene, or 2 - fluorotoluene. Although the names are different, they are actually the same thing. Merchants call it, or according to common practice, or from convenience, so many coexist. Scholars study, strive for accuracy, but also need to identify its synonyms in detail. In this way, in all things in the chemical industry, it can be clear and smooth, so as to avoid confusion, so as to facilitate the prosperity of the industry and smooth research.
Safety & Operational Standards
1 - Fluoro - 2 - Methylbenzene is an organic compound. It is essential to its safety and operating practices. It needs to be discussed in detail.
This compound is toxic and can endanger health if it touches the skin, inhales or is taken by mistake. Therefore, when operating, it is necessary to strictly follow safety procedures. Before starting the experiment, the experimenter should wear complete protective equipment, such as laboratory clothes, gloves and goggles, to prevent the substance from coming into direct contact with the body. Operate in a well-ventilated environment, preferably in a fume hood, so that volatile harmful gases can be dissipated in time and the risk of inhalation can be reduced.
In terms of storage, 1 - Fluoro - 2 - Methylbenzene should be placed in a cool, dry and ventilated place, away from fire and heat sources, because it is flammable. At the same time, it should be stored separately from oxidizers, acids, etc. to prevent dangerous reactions.
The operation process must also be rigorous. When taking the substance, use appropriate equipment, measure it accurately, and avoid spillage. If it is accidentally spilled, emergency measures should be taken immediately. A small amount of spillage can be absorbed by inert materials such as sand and vermiculite and collected in a suitable container; if a large amount of spillage, it needs to be evacuated, the scene should be sealed, and handled by professionals.
After the experiment is completed, the remaining 1 - Fluoro - 2 - Methylbenzene and related waste should not be discarded at will. It should be collected in accordance with regulations and handed over to professional institutions for disposal to avoid polluting the environment.
When operating 1 - Fluoro - 2 - Methylbenzene, safety must be given top priority and the operation specifications must be strictly followed, so as to ensure the safety of personnel and the smooth experiment.
Application Area
1 - Fluoro - 2 - Methylbenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key raw material for the synthesis of many special drugs. Because of its unique chemical structure, it can interact with specific receptors in organisms, helping to develop new drugs for the treatment of difficult diseases.
In materials science, this compound can be used to create new functional materials. For example, after special treatment, it can improve the stability and conductivity of materials, providing new opportunities for the development of electronic devices, optical materials, etc.
In the fragrance industry, 1 - Fluoro - 2 - Methylbenzene can endow fragrances with unique aroma characteristics. Because of its special smell, a unique fragrance can be prepared to meet the pursuit of different consumers for unique fragrances. From this point of view, 1 - Fluoro - 2 - Methylbenzene is of great value in various application fields, and it is a substance that cannot be ignored in chemical research and industrial production.
Research & Development
1 - Fluoro - 2 - Methylbenzene is also an organic compound. Our generation has studied it here, hoping to make progress. At first, I studied its molecular structure in detail, knew the wonder of its atomic arrangement, and revealed its chemical properties. Then I explored its synthesis method. After many attempts, I used different raw materials and different reaction conditions to achieve high efficiency.
Between experiments, its performance in different environments was observed, and changes in temperature and pressure were recorded in detail. The properties of this compound can be used in many fields. Those who are medicinal may be able to make special drugs according to their properties; those who are materials may be able to use their properties to develop novel materials.
We will work tirelessly on this, explore in depth, and hope to expand the field of its application, and promote this compound to a higher level in the process of research and development, which will contribute to the academic and industry.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons is also essential. Today, 1-Fluoro-2-Methylbenzene is used for research.
To observe its physical properties, or signs of toxicology. In various experiments, observe its effect on living beings. Small animals touch it, or see physiological violations. Its entry into the body, or the ability to mess with the viscera, disturbs the flow of qi and blood.
And this thing is also in the environment, there is a risk of migration. Or sewage soil, or staining the air, the harm is not shallow. Although industrial use has its advantages, the poison cannot be prevented.
For the sake of today's plan, we should deeply investigate the cause of its toxicity and investigate the path of its harm in detail. Only by devising exquisite methods can we avoid its poison in the early stage, protect the safety of the living soul, and maintain the tranquility of the environment.
Future Prospects
Today there is a product named 1 - Fluoro - 2 - Methylbenzene. We study it and find it promising in the future. This material is unique and may be useful in various fields of chemical industry.
Looking at today's chemical industry, the demand for many materials is increasing, and the characteristics of 1 - Fluoro - 2 - Methylbenzene may pave the way for the development of new materials. Its activity in the reaction can lead to the formation of unique compounds, providing an opportunity for the creation of efficient and specific materials.
Looking to the future, with the improvement of scientific research, we may be able to find better methods to produce it, reduce its cost and increase its yield. And in the pharmaceutical, electronics and other industries, it is expected to emerge and become the driving force for the industry to move forward. We should study it diligently and explore its potential, hoping that it will shine in the future, be used by the world, and benefit all people.
Where to Buy 1-Fluoro-2-Methylbenzene in China?
As a trusted 1-Fluoro-2-Methylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-2-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1-Fluoro-2-Methylbenzene?
1-Fluoro-2-methylbenzene, also known as o-fluorotoluene, is one of the organic compounds. This substance has unique physical properties, so let me tell you one by one.
Looking at its properties, under room temperature and pressure, 1-fluoro-2-methylbenzene is a colorless and transparent liquid. Its appearance is plain, but it contains its own characteristics. Its smell is quite special, with a fragrant smell, but it is different from the common fragrance. It is slightly irritating. Although this smell is not pungent or intolerable, it cannot be ignored.
When it comes to boiling point, the boiling point of 1-fluoro-2-methylbenzene is about 115 ° C to 117 ° C. At this temperature, it transforms from liquid to gaseous state, and the molecular motion intensifies, breaking free from the liquid phase. The value of the boiling point is affected by the intermolecular force, which determines the phase transition of 1-fluoro-2-methylbenzene in this temperature range.
In terms of melting point, it is about -57.3 ° C. When the temperature drops below the melting point, the thermal motion of the molecules weakens, and the arrangement of each other tends to be regular, and the substance solidifies from liquid to solid. This melting point indicates that 1-fluoro-2-methylbenzene solidifies at a relatively low temperature, and the daily ambient temperature is mostly higher than this, so it is usually a liquid state.
In terms of density, the density of 1-fluoro-2-methylbenzene is less than that of water, about 0.991g/cm ³. This property makes it float on the water surface when mixed with water, and the two are stratified. Due to the different way of intermolecular accumulation from water, the mass per unit volume is different.
Solubility is also an important physical property. 1-fluoro-2-methylbenzene is insoluble in water. Because it is an organic compound, the molecular polarity is weak, while water is a polar molecule. According to the principle of "similar miscibility", the two are difficult to miscible. However, in organic solvents, such as ethanol, ether, etc., 1-fluoro-2-methylbenzene has good solubility, and can be mixed with each other because it is compatible with the forces between organic solvent molecules.
In addition, 1-fluoro-2-methylbenzene is volatile and will gradually evaporate in the air, which is caused by the thermal movement of molecules to escape some molecules from the liquid surface. And because it is a flammable liquid, it is very easy to burn in case of open flames and hot topics. When using and storing, special attention should be paid to fire and explosion protection to ensure safety.
What are the chemical properties of 1-Fluoro-2-Methylbenzene?
1-Fluoro-2-methylbenzene is also an organic compound. It has various chemical properties, which are described in detail as follows:
First, its substitution reaction. Because the benzene ring has a fluorine atom and a methyl group, the two have different effects on the electron cloud density of the benzene ring. The methyl group is the power supply group, which increases the electron cloud density of the ortho and para-position, and the electrophilic substitution reaction is prone to occur in the ortho and para-position. For example, with bromine in the catalysis of iron bromide, the bromine atom tends to replace the ortho and para-position of the methyl group. Although the fluorine atom has an electron-sucking induction effect, its lone pair electrons are conjugated with the benzene ring, and there is a electron supply conjugation effect. The
times and addition reactions. The unsaturation of the benzene ring makes 1-fluoro-2-methylbenzene can be added to hydrogen and the like. In the presence of suitable catalysts such as nickel, the benzene ring can be gradually hydrogenated under heating conditions to form saturated alicyclic compounds.
Furthermore, it has an oxidation reaction. Methyl can be oxidized. In case of strong oxidants such as acidic potassium permanganate solution, methyl can be oxidized to carboxyl groups to give 1-fluoro-2-benzoic acid.
It also reacts with metal-organic reagents. If reacted with magnesium, Grignard reagents can be obtained. This Grignard reagent has strong nucleophilic properties and can react with many electrophilic reagents containing carbonyl groups. It has a wide range of uses in organic synthesis.
1-fluoro-2-methylbenzene The presence of fluorine and methyl is rich in chemical properties and plays an important role in organic synthesis and other fields. It can be converted into other organic compounds through various reactions.
What are the main uses of 1-Fluoro-2-Methylbenzene?
1-Fluoro-2-methylbenzene, also known as o-fluorotoluene, is a crucial raw material in organic synthesis and is widely used in many fields.
First, in the field of pharmaceutical synthesis, this compound is a key intermediate. It can be converted into compounds with specific pharmacological activities through a series of chemical reactions, and then used to create various drugs. For example, in the synthesis path of some antibacterial drugs, the reaction steps involved in 1-fluoro-2-methylbenzene play a decisive role in the construction of the core structure of drug molecules, laying the foundation for the development of new antibacterial drugs.
Second, in the field of pesticides, 1-fluoro-2-methylbenzene also plays an important role. Using it as a starting material, a variety of high-efficiency pesticides can be synthesized. Such pesticides can effectively control crop diseases and pests, and improve crop yield and quality. For example, the preparation of some pesticides, 1-fluoro-2-methylbenzene, after ingenious chemical modification, the generated products have highly targeted and killing effects on specific pests, and have relatively little impact on the environment, which meets the needs of modern green agriculture development.
Third, in the field of materials science, 1-fluoro-2-methylbenzene can be used as a raw material for the synthesis of special functional materials. Polymer materials with unique properties can be prepared by polymerization or blending with other compounds. For example, some materials with excellent optical properties or thermal stability, the participation of 1-fluoro-2-methylbenzene gives the material a special structure and properties, which meets the strict requirements of high-performance materials in the fields of electronics and optics.
In addition, 1-fluoro-2-methylbenzene is also involved in the fine chemical industry such as fragrances and dyes. In the synthesis of fragrances, its participation can give the fragrance a unique aroma; in the preparation of dyes, it helps to build special chromophore groups and improve the color and stability of dyes. In summary, 1-fluoro-2-methylbenzene has shown irreplaceable value in many fields due to its unique chemical structure, promoting the continuous development and progress of various related industries.
What are the preparation methods of 1-Fluoro-2-Methylbenzene?
1-Fluoro-2-methylbenzene, also known as o-fluorotoluene, is prepared by the following methods.
One is halogenation. With o-toluidine as the starting material, through diazotization reaction, o-toluidine is converted into a diazonium salt. Subsequently, the diazonium salt is reacted with fluoroborate acid to form a fluoroborate precipitation. After separation, drying, and then thermal decomposition, o-fluorotoluene can be obtained. In this process, the diazotization reaction needs to be handled carefully, and the reaction temperature and pH should be strictly controlled, otherwise it is easy to produce side reactions and affect the purity and yield of the product. The chemical reaction is roughly as follows: o-toluidine first reacts with sodium nitrite and hydrochloric acid to form diazonium salt, and then the diazonium salt reacts with fluoroboronic acid, and finally thermally decomposes to obtain o-fluorotoluene.
The second is the direct fluorination method. Toluene is used as the raw material and reacts directly with fluorine gas in the presence of a specific catalyst. Although the reaction process is simple, the fluorine gas activity is extremely high, the reaction is violent, the selectivity is difficult to control, and it is easy to generate by-products such as polyfluorinated substitutes. Therefore, the reaction equipment and process conditions are strict, and parameters such as reaction temperature, pressure, and fluorine gas inlet rate need to be precisely adjusted to improve the yield and purity of o-fluorotoluene.
The third is the hal Using o-chlorotoluene or o-bromotoluene as the substrate, and metal fluorides, such as potassium fluoride, under the action of suitable solvents and catalysts, the halogen exchange reaction occurs. This reaction condition is relatively mild and convenient to operate. However, it is crucial to choose a high-efficiency catalyst and a suitable solvent. For example, the use of crown ether compounds as catalysts can enhance the activity of metal fluorides and improve the reaction efficiency and selectivity. At the same time, the reaction process needs to be fully stirred to ensure that the substrate is fully in contact with metal fluorides to promote the reaction.
All the above preparation methods have advantages and disadvantages. In practical application, the appropriate method needs to be carefully selected according to factors such as specific needs, raw material availability, cost considerations and equipment conditions.
What 1-Fluoro-2-Methylbenzene need to pay attention to when storing and transporting
1-Fluoro-2-methylbenzene is an organic compound. During storage and transportation, many things need to be paid attention to to ensure safety.
First, when storing, be sure to choose a cool and well-ventilated place. This is because it is volatile to a certain extent, high temperature will increase volatilization. If it is in a closed environment, it may accumulate to dangerous concentrations, causing safety hazards. A cool environment can effectively reduce its volatilization rate. Well ventilated can disperse volatile gases in time to avoid gas accumulation.
Second, keep away from fire and heat sources. 1-Fluoro-2-methylbenzene is a flammable substance that can cause combustion and explosion in case of open flame and high heat energy. Even a little spark may trigger a serious accident, so fireworks are strictly prohibited in storage and transportation sites, and all electrical equipment, lighting facilities, etc. should have explosion-proof functions.
Third, it should be stored separately from oxidants, acids, alkalis, etc., and must not be mixed in storage and transportation. Due to its active chemical properties, contact with oxidants may cause severe oxidation reactions or even explosions; contact with acids and alkalis may cause chemical reactions, cause deterioration of substances, and may produce harmful gases, threatening personnel and the environment.
Fourth, storage containers must be tightly sealed. In order to prevent leakage, because the volatile gas will not only pollute the environment, but also damage human health, such as irritating the respiratory tract, nervous system, etc. In the event of a leak, personnel in the contaminated area should be quickly evacuated to a safe area, isolated, and strictly restricted access. Emergency personnel need to wear self-contained positive pressure breathing apparatus, wear anti-toxic clothing, and cut off the source of leakage as much as possible.
Fifth, during transportation, ensure that the container does not leak, collapse, fall, or damage. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. In summer, it is best to transport in the morning and evening to prevent sun exposure. During the journey, follow the prescribed route and do not stop in residential areas and densely populated areas.
Only by strictly following the above precautions can we ensure the safety of 1-fluoro-2-methylbenzene during storage and transportation, avoid accidents, and protect people's lives and the environment.