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1-Fluoro-2-Iodo-5-Nitrobenzene

1-Fluoro-2-Iodo-5-Nitrobenzene

Hongda Chemical

Specifications

HS Code

395633

Chemical Formula C6H3FINO2
Appearance Solid
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Purity Typically high - purity in commercial products

As an accredited 1-Fluoro-2-Iodo-5-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - fluoro - 2 - iodo - 5 - nitrobenzene packaged in a sealed glass bottle.
Storage 1 - fluoro - 2 - iodo - 5 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture and air exposure. Store it separately from incompatible substances like oxidizing agents and reducing agents to avoid potential reactions. Use a dedicated storage space with proper signage for easy identification and safety.
Shipping 1 - fluoro - 2 - iodo - 5 - nitrobenzene, a chemical, is shipped in well - sealed, corrosion - resistant containers. Special care is taken to prevent leakage, following strict hazardous materials shipping regulations for safe transportation.
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1-Fluoro-2-Iodo-5-Nitrobenzene 1-Fluoro-2-Iodo-5-Nitrobenzene
General Information
Historical Development
1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene, the substance of chemistry. Tracing its historical evolution, chemical sages in the past explored the mysteries of matter, and in the field of organic synthesis, after years of study, this compound was born.
At the beginning, organic chemistry was still in its infancy, and researchers were committed to analyzing the possibility of various element combinations. After countless attempts and failures, the law of material reaction has gradually become clear. And science is gradually emerging, instruments are refined, and synthesis methods are abundant.
In the study of aromatic derivatives, people have improved the reaction conditions and optimized the synthesis path for this compound. From the initial difficult synthesis, the yield was low, to the later generations, continuous improvement, the yield gradually increased, and the purity was also good. From the simple theoretical exploration in the past to the wide application in medicine, materials and other fields today, the historical evolution of 1-Fluoro-2-Iodo-5-Nitrobenzene highlights the unremitting progress and brilliant achievements of chemical research.
Product Overview
1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene is an organic compound. Its shape and color, at room temperature, or as a crystalline solid, have specific physical properties. Its structure is unique. On the benzene ring, fluorine, iodine, and nitro groups interact according to their positions, and this excipient has specific chemical properties.
The method of preparation often involves the technique of organic synthesis. Using benzene as a group, fluorine, iodine, nitro and other groups are gradually introduced through halogenation and nitrification reactions. In the reaction, the control of various conditions is the key, and the temperature, solvent, catalyst, etc. are all related to the yield and purity of the product.
This substance has a wide range of uses. In the field of medicinal chemistry, it can be used as an intermediate for the synthesis of specific drugs. With its special structure, it participates in the construction of drug molecules to achieve therapeutic effect. In material science, or as a raw material for the preparation of special functional materials, it endows materials with different properties due to its own properties. It is an important compound that cannot be ignored in organic chemistry research and industrial applications.
Physical & Chemical Properties
1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene is an organic compound. Its physical and chemical properties are quite specific. Looking at its shape, at room temperature, or in a crystalline state, it is slightly yellow in color and has a specific crystal structure, which is related to the order of its molecular arrangement. Regarding its melting point, after accurate determination, it can reach a certain fixed temperature, which is due to the intermolecular force. As for the boiling point, it also has a specific value, reflecting the energy required for its gasification.
Its chemical properties are active, and the functional groups of fluorine, iodine, and nitro give it unique reactivity. Nitro has strong electron absorption, which reduces the density of the electron cloud of the benzene ring and is easy to lead to electrophilic substitution reactions. The atomic properties of fluorine and iodine allow them to participate in various transformations of halogenation reactions under specific conditions. This compound is often a key intermediate in the field of organic synthesis. With its special physical and chemical properties, it can build a variety of complex organic structures and is important for chemical research and industrial production.
Technical Specifications & Labeling
1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene, it is also a thing of transformation. Its technical quality (product quality) is important. The technical quality of this product needs to be refined and clear, and each index is clear. If it contains the proportion of ingredients, it must be consistent with the science. Its physical reason, such as melting and boiling, also needs to be clarified. As for the price, it is possible to identify the characteristics of this product. On the package, its name should be clearly confirmed, and the name of 1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene should not be ambiguous. And there are warning signs, such as toxicity and danger, must also be conspicuous, so that the user can understand it, so as to be safe. In this way, the manufacture, circulation and use of this product can be guaranteed in an orderly and safe manner.
Preparation Method
1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene is an important compound in organic synthesis. The preparation method is crucial to the selection of raw materials. Usually, related aromatic hydrocarbons containing fluorine, iodine and nitro groups are used as starting materials.
In the synthesis process, a specific aromatic hydrocarbon and a fluorinated reagent are introduced through a nucleophilic substitution reaction under suitable reaction conditions. This step requires precise control of the reaction temperature, time and reagent dosage to ensure that the fluorine atoms are connected to the target position as expected.
Next, an iodine substitution reagent is added, and an iodine atom is introduced through a substitution reaction again. During the reaction process, the pH of the reaction environment, solvent type and other factors are carefully regulated to ensure the efficient progress of the iodine substitution reaction.
After fluorine and iodine atoms are successfully integrated, nitro groups are introduced through nitrification reaction. The reaction process is strictly monitored to optimize the reaction parameters and improve the purity and yield of the product. At the same time, a reasonable reaction mechanism is constructed to ensure that each step of the reaction occurs in sequence and efficiently, so as to achieve high-quality preparation of 1-Fluoro-2-Iodo-5-Nitrobenzene.
Chemical Reactions & Modifications
Since modern times, chemistry has been refined, and the study of various reactions and physical properties has become increasingly detailed. Today there is 1-Fluoro-2-Iodo-5-Nitrobenzene, which is very important in chemical research.
Its chemical reaction is formed by the combination of many factors. Fluorine, iodine, and nitro belong to the genera, each of which has its own characteristics and affects each other during the reaction. Fluorine has strong electronegativity, which often leads to the change of electron clouds, which makes the electron density of the benzene ring different and causes different reactivity. Although iodine has a large atomic radius, it also plays an important role in the reaction path, or is a leaving group, which promotes the reaction to move forward. Nitro groups have strong electron-absorbing properties, which reduce the electron cloud density of the benzene ring, making electrophilic substitution reactions difficult, but adding help to nucleophilic substitution and other reactions.
As for physical properties, due to the characteristics of each group, the melting boiling point and solubility of 1-Fluoro-2-Iodo-5-Nitrobenzene all have their own unique characteristics. The melting boiling point is related to the intermolecular force, and the polarity and relative molecular mass of the groups are all controlled. Solubility is also restricted by molecular polarity and solvent properties.
The study of the reaction and physical properties of this substance is of great significance in the fields of chemical synthesis, materials science, etc., and can help our generation explore new paths and explore the unknown.
Synonyms & Product Names
1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene, its synonymous name and the name of the commodity, are related to the importance of chemical inquiry. The name of the chemical substance often varies depending on the domain used and the habits of the researcher. This 1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene, or is called by another name.
In the academic world, various sages or according to their structure and nature, give synonymous names, wanting to express their precise meanings so that their peers can clarify their characteristics. Among businesses, merchants trade, promote, or give the name of the commodity to attract attention.
We chemical researchers must scrutinize their synonymous names and commodity names to clarify their similarities and differences. Only in this way can we avoid confusion and use them accurately during research, so as to facilitate the smooth flow of inquiry, explore their mysteries in the field of chemistry, and promote academic progress and industrial prosperity.
Safety & Operational Standards
1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene is a chemical substance. It is crucial to its safety and operation specifications and should not be ignored.
At the time of preparation, the use of all raw materials should be based on accurate measurements. The utensils used should also be clean and dry to prevent impurities from mixing and causing reactions. The temperature, pressure and other conditions of the reaction environment must be strictly controlled, because it has a great impact on the formation and quality of the product.
When storing, this compound should be placed in a cool, dry and well ventilated place. Keep away from fire and heat sources to prevent accidents. Because of its certain danger, the storage place should be set up with obvious warning signs, so that everyone can be alert.
During the operation, the operator must wear appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to ensure their own safety. If you accidentally touch the skin or eyes, rinse with plenty of water immediately and seek medical attention in time. If a leak occurs during operation, do not panic, evacuate the surrounding personnel quickly, and take effective measures to clean up the leak to avoid its spread and cause greater harm.
Furthermore, the disposal of this compound should also follow strict regulations. Do not discard it at will, and dispose of it properly in accordance with relevant laws and regulations to avoid pollution to the environment.
In conclusion, the safety and operation of 1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene must be strictly adhered to throughout the entire process of preparation, storage, use and disposal to ensure the safety of people, the environment and production.
Application Area
1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene is also a chemical substance. It can be used to create special effects in the field of technology. With its unique properties, it can create a delicate reaction, helping to form the basis of chemical activity. In the world of materials, it also exhibits amazing capabilities. Or it can be used as a special agent to increase the resistance and wear resistance of materials; or it can be used to improve the material's quality. In the process of synthesis, it is an important raw material. It can be used to create all kinds of chemical substances and expand the realm of synthesis. In addition, 1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene has extraordinary watches in the field, promoting the best of technology and benefiting the world.
Research & Development
Today there is a substance, named 1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene. We are committed to studying it and hope to make progress.
When studying this substance, first investigate its properties. Looking at its structure, fluorine, iodine, nitro are combined with benzene ring. This unique structure must give it the properties of being different from normal substances. Its chemical activity is related to the direction of reaction, and it is really important to study.
Furthermore, observe the method of its preparation. Looking for an efficient and pure method is essential for making this substance. The ancient method may have the disadvantages of being complicated and the yield is not high. Now we should seek a new way to make it better.
I also think about the use of this substance. In the fields of medicine and materials, it may be of great use. If we can understand its use and apply it to the world, it will be a blessing for the researchers.
We should make every effort to explore its mysteries and seek its progress. It is beneficial to use this thing for learning and the world.
Toxicity Research
1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene is also a chemical substance. We have studied the toxicity of this substance to find out.
The toxicity of this substance is at the end of the spectrum. It contains fluorine, iodine, and nitro groups. The activity of fluorine is low, and the nitro group is oxidizing, or it can cause chemical reactions, and harm organisms.
It is high, and it is like a chemical. It is cast with this substance, and it is reversed. It has mental weakness, poor food intake, and even physiological performance. This shows its toxicity.
It is also considered in the environment, or in the process of hydrolysis and photolysis, to produce harmful substances and endanger health. Therefore, it is necessary to study its toxicity, in order to avoid its use, use, and health, and to ensure the safety of the environment and the health of the organism.
Future Prospects
The future is about 1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene, and I am full of expectations. In today's world, chemical research is changing with each passing day. This substance has unique characteristics, or it has emerged in the fields of pharmaceutical creation and material innovation.
Looking at medicine, its structure may be the key to new drugs, unlocking new ways to treat difficult diseases. It can accurately target the focus and reduce the suffering of patients. As for materials, it may become the foundation of high-tech materials, endowing materials with unique properties, such as high photoelectric conversion efficiency and excellent mechanical properties.
I believe that with time, 1 - Fluoro - 2 - Iodo - 5 - Nitrobenzene will shine. In the years yet to come, it will inspire industrial change, add luster to human well-being, pave a bright and prosperous road, and make our lives new and beautiful.
Where to Buy 1-Fluoro-2-Iodo-5-Nitrobenzene in China?
As a trusted 1-Fluoro-2-Iodo-5-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-2-Iodo-5-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Fluoro-2-Iodo-5-Nitrobenzene?
1-Fluoro-2-iodine-5-nitrobenzene is an important compound in the field of organic synthesis. Its main uses can be classified as the following numbers.
First, in the field of pharmaceutical chemistry, this compound is often used as a key intermediate. Through a series of organic reactions, such as nucleophilic substitution reactions, its structure can be modified to construct a molecular structure with specific biological activities. On this basis, it can synthesize a variety of drug molecules, or show potential therapeutic effects on certain diseases. For example, by carefully designing subsequent reactions, or generating small molecule inhibitors targeting specific targets, it is expected to be applied to the development of anti-tumor, anti-viral drugs.
Second, in the field of materials science, 1-fluoro-2-iodine-5-nitrobenzene also has important value. Due to its unique electronic structure and chemical properties, it can be used to prepare functional materials. For example, it participates in the synthesis of conjugated polymers, endowing materials with special electrical and optical properties. By skillfully adjusting the reaction conditions and molecular structure, materials with good photoelectric conversion properties may be prepared, which may have application prospects in organic Light Emitting Diode (OLED), solar cells and other fields.
Third, this compound also plays an important role in the preparation of fine chemical products. It can be used as a starting material to synthesize fine chemicals with special structures, such as special dyes and fragrances, through multi-step reactions. Through precise control of its reaction path and product structure, it can meet the diverse needs of fine chemicals in different industries.
All in all, 1-fluoro-2-iodine-5-nitrobenzene has a wide range of critical uses in many fields such as medicine, materials, and fine chemicals due to its unique chemical structure, promoting technological innovation and Product Research & Development in various fields.
What are the physical properties of 1-Fluoro-2-Iodo-5-Nitrobenzene?
1-Fluorine-2-iodine-5-nitrobenzene is also an organic compound. Its physical properties are quite characteristic, let me talk about them one by one.
Looking at its properties, at room temperature, it is mostly in a solid state. This is due to the interaction between molecules, which makes it have a relatively stable structure. Its melting point is also an important physical property. The melting point is determined by the interaction between atoms in the molecule and the interaction between molecules. When the temperature rises to a certain level, the molecule obtains enough energy to overcome the lattice energy and convert from solid to liquid. The boiling point is related to the energy required for the molecule to leave the liquid state and enter the gas state, reflecting the strength of the intermolecular force.
As for solubility, 1-fluoro-2-iodine-5-nitrobenzene often has a certain solubility in organic solvents. For example, in common organic solvents such as ether and chloroform, it can be partially dissolved. Due to the molecular structure of the compound, fluorine, iodine, nitro and other groups endow it with a certain polarity, and interact with the polarity of the organic solvent, so it is soluble. However, in water, its solubility is very small, and edge water is a strong polar solvent, which does not match the intermolecular force of the compound and is difficult to miscible.
Its density is also a significant physical property. Due to the fact that the molecule contains elements with relatively large atomic mass such as fluorine and iodine, its density is higher than that of water and some common organic solvents. This property is suitable for practical applications or can be used for separation and other operations.
In addition, the color state of 1-fluoro-2-iodine-5-nitrobenzene is usually colorless to light yellow. The generation of this color is related to the transition of electrons in the molecule. The specific structure causes it to absorb and reflect light in a specific manner, resulting in a corresponding color state.
In summary, the physical properties of 1-fluoro-2-iodine-5-nitrobenzene, such as solid-liquid state, melting boiling point, solubility, density, color state, etc., are determined by its molecular structure, and have important effects and applications in many fields such as organic synthesis and chemical production.
What is the chemistry of 1-Fluoro-2-Iodo-5-Nitrobenzene?
1-Fluoro-2-iodine-5-nitrobenzene is one of the organic compounds. In its molecular structure, fluorine, iodine and nitro are each located in a specific position according to the benzene ring. The chemical properties of this compound are very interesting and closely related to various chemical reactions.
First talk about its substitution reaction. Above the benzene ring, due to the presence of nitro groups, the electron cloud density of the benzene ring decreases, resulting in the weakening of its electrophilic substitution reaction activity. However, the substitution of fluorine and iodine has their own characteristics. Fluorine atoms have small radii and large electronegativity. Although they can participate in the substitution reaction, their reaction conditions are relatively harsh. The iodine atomic radius is large, the C-I bond energy is relatively small, and it is easy to be substituted. It can often be replaced by other nucleophiles under suitable conditions.
Re-discuss its reduction reaction. Nitro groups have strong oxidation and can be reduced under the action of appropriate reducing agents. Common such as iron and hydrochloric acid as reduction systems, nitro groups can be gradually converted into amino groups. This process provides an important way for the preparation of compounds containing amino groups in organic synthesis.
In addition, because fluorine, iodine, and nitro groups all have electron-withdrawing properties, the acidity of this compound is also changed compared with benzene. It can participate in acid-base related reactions and is of great significance in organic synthesis and reaction mechanism research.
In addition, the stability of 1-fluoro-2-iodine-5-nitrobenzene is also related to the interaction of various groups in the structure. The spatial and electronic effects of each group coexist, which jointly affect the overall properties of the compound. The space occupancy of fluorine and iodine, as well as the electronic effect of nitro groups, make the molecular structure exhibit unique stability and reactivity. This compound is used in the field of organic synthesis, or as a key intermediate, to participate in the construction of many complex organic molecules, adding rich content to the research and application of organic chemistry.
What are 1-Fluoro-2-Iodo-5-Nitrobenzene synthesis methods?
The synthesis method of 1-fluoro-2-iodine-5-nitrobenzene is often related to the delicate technology of organic synthesis. One method is to use benzene as the initial raw material, and first perform nitrification to introduce nitro groups into the benzene ring. This step requires selecting a suitable nitrifying agent, such as a mixed acid of concentrated nitric acid and concentrated sulfuric acid, and controlling the temperature within an appropriate range of about 50-60 ° C, to obtain nitrobenzene.
Then, the halogenation reaction of nitrobenzene is carried out. The fluorine atom is introduced first, and the method of nucleophilic substitution can be selected. A specific fluorine-containing agent, such as potassium fluoride, is used in an organic solvent. Under the help of high temperature and catalyst, the specific position of nitrobenzene is replaced by fluorine atoms to obtain fluorine-containing nitro
Then, the iodine atom is introduced. The iodine atom can be connected to the benzene ring by electrophilic substitution reaction with iodine elemental substance and appropriate oxidant, such as hydrogen peroxide, under mild conditions in the presence of a catalyst, and the final product is 1-fluoro-2-iodine-5-nitrobenzene.
Another way is to start with other compounds that already contain part of the target group. For example, this product can also be obtained by using 2-iodine-5-nitroaniline as a raw material, undergoing diazotization reaction, then treating with fluoroboronic acid, and then heating decomposition to realize the conversion of amino groups to fluorine atoms. In this process, the diazotization reaction needs to control the temperature and the amount of reagents to prevent side reactions from breeding. All synthesis methods need to be carefully selected according to the actual situation, considering the availability of raw materials, the difficulty of reaction, and the high or low yield.
1-Fluoro-2-Iodo-5-Nitrobenzene to pay attention to when storing and transporting
1-Fluoro-2-iodine-5-nitrobenzene is also an organic compound. During storage and transportation, many matters must be paid attention to.
First words storage. This material has a certain chemical activity and should be stored in a cool, dry and well-ventilated place. Due to high temperature and humidity, it is easy to cause its chemical changes and damage its quality. The temperature of the warehouse should be controlled within a suitable range, and it should not be too high to prevent dangerous reactions. And it should be separated from oxidants, reducing agents, alkalis and other substances, because it is easy to react chemically with such substances, or cause accidents.
Then transport. When transporting, be sure to ensure that the packaging is complete and well sealed. Use appropriate packaging materials to resist vibration, collision and leakage. Transportation vehicles also need to be clean and dry, and there is no residual material that can react with them. During transportation, drivers should drive carefully to avoid severe actions such as sudden braking and sharp turns, which will cause damage to the packaging. And the transportation environment should also maintain suitable temperature and humidity, and should not expose it to extreme conditions.
In addition, whether it is storage or transportation, relevant personnel need to be familiar with the characteristics and dangers of this compound and prepare corresponding emergency measures. In case of emergencies such as leaks, they can be disposed of quickly and properly to minimize harm.