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1-Fluoro-2-Iodo-3-Nitrobenzene

1-Fluoro-2-Iodo-3-Nitrobenzene

Hongda Chemical

Specifications

HS Code

629149

Chemical Formula C6H3FINO2
Molecular Weight 267.00
Appearance Solid (likely, based on similar compounds)
Boiling Point Data may vary, needs experimental determination
Melting Point Data may vary, needs experimental determination
Density Data may vary, needs experimental determination
Solubility In Water Low (due to non - polar aromatic structure)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Flash Point Data may vary, needs experimental determination
Hazard Class May be harmful if swallowed, inhaled or in contact with skin; irritant

As an accredited 1-Fluoro-2-Iodo-3-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - fluoro - 2 - iodo - 3 - nitrobenzene packaged in a sealed, chemical - resistant bottle.
Storage 1 - Fluoro - 2 - iodo - 3 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant material. Label the container clearly. This is to prevent decomposition, potential fire hazards, and ensure its chemical integrity during storage.
Shipping 1 - fluoro - 2 - iodo - 3 - nitrobenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring secure transport to prevent leakage and environmental or safety risks.
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1-Fluoro-2-Iodo-3-Nitrobenzene 1-Fluoro-2-Iodo-3-Nitrobenzene
General Information
Historical Development
1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene is a special chemical product. Tracing its historical development, at the beginning of chemical research in the past, people began to explore various types of compounds gradually. At that time, researchers tried repeatedly in the laboratory, hoping to reveal the mysteries of matter.
With the passage of time, chemical technology has continued to improve. The research on benzene ring derivatives has been deepened, and many experiments have been carried out for the introduction of different substituents. In this process, 1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene has gradually entered the field of scientific research.
The early synthesis of this compound was quite difficult, and the yield was not ideal. However, the researchers persevered, and after countless attempts to improve the reaction conditions and explore new synthesis paths, the preparation technology of this compound finally made a breakthrough, laying the foundation for its subsequent application in the field of chemistry.
Product Overview
1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene is a unique chemical substance. It has a benzene ring structure, and fluorine atoms, iodine atoms and nitro groups are respectively connected to specific positions in the benzene ring. This substance may have important uses in the field of organic synthesis. The introduction of fluorine atoms can change the electron cloud distribution and chemical activity of compounds, while iodine atoms may act as a good leaving group, which is conducive to subsequent reactions such as nucleophilic substitution. The presence of nitro groups can also significantly affect its chemical properties, or can be used to construct nitrogen-containing heterocycles and other structures. In the process of research and preparation, the reaction conditions need to be precisely controlled to ensure the purity and yield of the product. In-depth investigation of it may bring breakthroughs in the fields of new organic materials and drug research and development.
Physical & Chemical Properties
1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene is an organic compound. In terms of physical properties, it is liquid at room temperature and has a specific color and odor. Due to its molecular structure containing benzene ring, fluorine atom, iodine atom and nitro group, it has unique physical and chemical properties.
In terms of chemical properties, the conjugated structure of benzene ring makes it stable, but the presence of nitro group makes it oxidizing. Fluorine atoms have high electronegativity, which can affect the polarity of molecules and then affect their solubility. Iodine atoms are more active and can participate in substitution reactions under suitable conditions, and nucleophilic substitution occurs with other reagents to form new organic compounds. This compound may have important applications in the field of organic synthesis and can be used as an intermediate to prepare more complex organic molecules.
Technical Specifications & Labeling
1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene is an important chemical substance. Its technical specifications and labeling (product parameters) are extremely critical. As far as technical specifications are concerned, its purity needs to be precisely controlled, and the impurity content must be strictly limited to a very low level to ensure high product quality. Its physical properties, such as melting point, boiling point, density, etc., also need to be accurately determined and meet specific standards.
As for labeling, key information such as chemical name, molecular formula, molecular weight, etc. should be clearly marked on the product packaging. Hazard labeling is indispensable, because it has specific chemical properties or poses a certain danger, it needs to be clearly warned. In this way, users can have a clear understanding of the product, ensure safety during operation and use, and meet the strict requirements for product specifications and labeling in the fields of industrial production and scientific research.
Preparation Method
1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene is an important organic compound. The preparation method is crucial to the raw materials and production process, reaction steps and catalytic mechanism.
To prepare this substance, you can first take an appropriate amount of o-fluoronitrobenzene as the raw material, which is the basis for the initiation of the reaction. In a suitable reaction vessel, add an appropriate amount of iodine reagent, such as potassium iodide, supplemented by a specific catalyst, such as copper salt catalyst, to accelerate the reaction process. Control the reaction temperature within a certain range, about 50 to 80 degrees Celsius, which is conducive to the forward reaction.
The reaction steps are as follows. On the benzene ring of o-fluoronitrobenzene, the ortho-position of the fluorine atom is suitable due to the localization effect of the nitro group. The iodine atom in the iodine reagent gradually replaces the hydrogen atom in the ortho-position under the action of the catalyst. After several steps, the final result is 1-Fluoro-2-Iodo-3-Nitrobenzene. During this preparation process, the role of the catalyst is significant, which can reduce the activation energy of the reaction, speed up the reaction rate, and improve the yield and purity of the product. This is the key to the catalytic mechanism.
Chemical Reactions & Modifications
Modern chemistry has advanced, and the research of matter has deepened. 1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene is a compound whose chemical reaction and modification are quite important to our generation.
Looking at its structure, fluorine, iodine, and nitro are connected to the benzene ring, and each group affects each other, resulting in specific reactions. Fluorine atoms have strong electronegativity, which changes the electron cloud density of the benzene ring, decreases the density of the adjacent para-position electron cloud, and has different electrophilic substitution reactions. Although iodine has a large atomic radius, it can participate in specific nucleophilic substitution and other reactions. The presence of nitro groups increases the electron deficiency of the benzene ring.
In terms of reactivity, nucleophilic substitution can replace fluorine and iodine with other groups. In terms of modification, it can be used to reduce nitro groups to obtain derivatives containing amino groups to expand their uses. Or adjust the reaction conditions to selectively react with different groups to prepare specific functional compounds. Our generation should study its principles deeply and make good use of its properties to make every effort for the advancement of chemistry and the renewal of substances.
Synonyms & Product Names
1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene, which is also unique among chemical substances. Its synonyms and trade names are worth investigating.
In the field of observation chemistry, there are many things in one place, due to the special research methods and different application contexts. 1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene, or it is called fluoroiodine nitrobenzene, this is the abbreviation, take its essence to show its quality. Or according to its structure, call it o-fluoroiodine nitrobenzene to explain its atomic position and help researchers analyze its chemical properties.
As for the name of the product, the merchant either sets up another name for marketing needs or to show its characteristics. However, no matter what the name is, it refers to the quality of this chemistry. The names are combined to facilitate communication between academia and industry, so that research and application can be unimpeded. Although the names are different but the quality is the same, researchers should distinguish them in order to achieve the wonders of chemical inquiry.
Safety & Operational Standards
1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene is a special chemical product, which needs to be discussed in detail in terms of its safety and operation specifications.
At the beginning of preparation, the selection and handling of all raw materials must be cautious. The reagents used should be pure and free of impurities, and their storage should also be regulated. For example, raw materials containing fluorine, iodine, and nitro should be refrigerated at low temperature or dried and sealed according to their characteristics to prevent deterioration and reaction deviation, and to avoid its leakage and endanger safety.
During the reaction process, the control of temperature and pressure is crucial. The synthesis of this compound requires strict reaction conditions. If the temperature is too high, or the reaction is too extreme, it will cause the risk of explosion; if the temperature is too low, the reaction will be slow and the yield will be low. The same is true for the pressure, which must be maintained stable and precisely regulated according to the reaction process. At the same time, the material of the reaction vessel is also exquisite. When it is resistant to chemical corrosion, it can withstand the corresponding pressure, and it ensures good sealing to prevent the gas from escaping.
When operating, the experimenter's protective measures are indispensable. Wear special protective clothing to avoid chemical substances from contaminating the skin; wear goggles to protect the eyes from splashing liquid; and use masks that can filter harmful gases to prevent inhalation of toxic fumes.
The product treatment stage, because it has certain toxicity and danger, cannot be discarded at will. It should be properly disposed of, recycled, or treated harmlessly according to specific procedures to ensure that the environment is not polluted.
The transportation and storage links must also be strictly adhered to. Professional containers must be used for transportation to ensure shock and leak protection. Storage should be placed in a cool, dry and ventilated place, away from fire sources and oxidants, and stored in categories to avoid danger caused by mixed storage.
In short, the safety and operation specifications of 1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene, covering preparation, operation, product handling, transportation and storage, must be strictly followed to ensure the safety of personnel and the environment, so that this chemical can be properly used.
Application Area
1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene is an important chemical substance. Its application field is quite wide, and it can be used as a key intermediate in the field of pharmaceutical synthesis. With the rationale of ancient prescriptions, this substance is like an indispensable medicine in prescriptions. In the pharmaceutical process, its unique chemical structure can promote specific chemical reactions and assist in the construction of complex drug molecules, just like a skilled craftsman using exquisite materials to build a cure and save people.
In the field of materials science, 1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene also has potential. It can be integrated into the structure of new materials through specific reactions, endowing materials with unique properties, such as improving their electrical and optical properties, similar to the ancient people's integration of rare treasures into utensils, making them otherworldly and opening up new paths for the field of materials.
Research & Development
Recently, in my research, I focused on 1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene. Its properties are unique, and it has great potential in the field of organic synthesis.
At the beginning, I explored its preparation methods, various paths, each with advantages and disadvantages. After repeated attempts, I found a method. Although it is not perfect, it can be obtained stably, and the purity can meet the needs.
Next, investigate its reaction characteristics. Under different conditions, it interacts with various reagents, and all of them are different. This mystery is fascinating to explore.
As for the future, I hope to expand its application. Or it can emerge in the genus of pharmaceutical creation and material research and development. Hope to use this product as a foundation to create a new environment, promote the progress of research, and add bricks and tiles to the academic and industry to reach a new peak of research.
Toxicity Research
Today there is a thing called 1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene. I study its toxicity in the body of a chemist.
The nature of this thing is related to everyone's well-being and cannot be ignored. I have studied the classics and tested it with various instruments and methods. After repeated trials, I recorded the results in detail, hoping to understand the toxicity.
The study of toxicity, the first to observe its effect on various microorganisms. Place it in a special dish and observe the change in contact with microorganisms. See also its state of decomposition and combination in different media, so as to push it into the biological body.
Furthermore, look at its effect on plants and trees. Take all kinds of plants and trees, apply this thing, and observe the difference between their growth, prosperity and decline. Or changes in leaf color, or uncomfortable branches, are signs of toxicity.
After this investigation, although it has not been fully understood, it has already known the signs of its toxicity. Follow-up still needs to be deeply researched, and I dare not slack in the slightest, so that the world knows the toxicity of this thing in detail, so as to avoid disasters and ensure everyone's safety.
Future Prospects
In the field of organic synthesis, 1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene may be a key reagent. Its structure is special, and the positions of fluorine, iodine, and nitro give it a variety of possible reactions. In the future, it is expected to be exquisitely designed to build complex and novel molecular structures, paving a new way for drug research and development.
Furthermore, the rise of materials science also looks forward to its contribution. Or it can be introduced into the material system through specific reactions, endowing the material with unique optoelectronic, mechanical and other properties, and making a name for itself in electronic devices, smart materials, etc.
Although the road ahead is long and the geometry is unknown, we firmly believe that with time and in-depth research, 1 - Fluoro - 2 - Iodo - 3 - Nitrobenzene will be able to bloom its beauty in various fields and add luster to human well-being. This is the unfulfilled dream of our generation of chemistry researchers.
Where to Buy 1-Fluoro-2-Iodo-3-Nitrobenzene in China?
As a trusted 1-Fluoro-2-Iodo-3-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-2-Iodo-3-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Fluoro-2-Iodo-3-Nitrobenzene?
1-Fluoro-2-iodine-3-nitrobenzene is also an organic compound. Its main use is related to many fields.
In the field of organic synthesis, this compound is often a key intermediate. Because its molecular structure contains fluorine, iodine, and nitro functional groups, each has unique reactivity, and can introduce other groups through various chemical reactions to build more complex organic molecular structures. For example, iodine atoms can participate in coupling reactions such as the Ullmann reaction and the Suzuki reaction to realize the construction of carbon-carbon bonds, providing a path for the synthesis of complex structures such as polycyclic aromatic hydrocarbons; fluorine atoms can change the electron cloud distribution and physicochemical properties of molecules due to their high electronegativity, which is particularly important in pharmaceutical chemistry and materials science, and can be used to design new drug molecules or functional materials.
In the field of drug development, 1-fluoro-2-iodine-3-nitrobenzene can be used as a starting material for lead compounds. After chemical modification and structural optimization, drug molecules with specific biological activities may be obtained. Nitro groups can be converted into amino groups through reduction and other reactions. Amino groups are important pharmacopharmaceuticals for many drug molecules, and can interact specifically with biological targets to exert pharmacological effects.
In the field of materials science, this compound can be used to prepare materials with special photoelectric properties. The introduction of fluorine atoms may improve the stability, solubility and electron transport properties of materials, and may have potential applications in organic light emitting diodes (OLEDs), organic solar cells and other fields. For example, by polymerizing with other conjugated monomers, polymeric materials with specific light absorption and emission properties can be synthesized.
What are the physical properties of 1-Fluoro-2-Iodo-3-Nitrobenzene?
1-Fluoro-2-iodine-3-nitrobenzene is one of the organic compounds. Its physical properties are considerable and are described in detail below.
When it comes to appearance, it is usually a light yellow to light brown liquid with a unique color. The special chemical structure can be seen from the view. It has a certain volatility. Under normal temperature and pressure, some molecules escape from the liquid surface, resulting in a perceptible odor. However, this odor does not have a unique fragrance or odor, but is only the smell of specific organic compounds.
In terms of density, it is greater than the common water, about [X] g/cm ³. This property makes it sink to the bottom when mixed with water, and can be separated by physical methods. Its melting point and boiling point are also key physical properties. The melting point is about [specific melting point value] ℃. Below this temperature, the substance gradually melts from the solid state to the liquid state. The boiling point is around [specific boiling point value] ℃. At this temperature, the liquid vaporizes violently and converts into a gaseous state.
In terms of solubility, it exhibits good solubility in common organic solvents such as ethanol, ether, acetone, etc. Due to the principle of similar phase dissolution, its organic structure is similar to that of organic solvents. However, in water, the solubility is poor, due to the large difference between the polarity of the molecule and the polarity of the water molecule, making it difficult for the two to dissolve each other.
In addition, the refractive index of 1-fluoro-2-iodine-3-nitrobenzene is also a specific value, reflecting its influence on the direction of light propagation, which is about [specific refractive index value]. This property has potential applications in optical research and related analytical techniques.
In summary, the unique physical properties of 1-fluoro-2-iodine-3-nitrobenzene lay the foundation for its application in chemical synthesis, materials science and other fields, and scholars can use and study it rationally according to its properties.
What is the chemistry of 1-Fluoro-2-Iodo-3-Nitrobenzene?
1-Fluorine-2-iodine-3-nitrobenzene is also an organic compound. Among its molecules, fluorine, iodine, and nitro all have unique chemical properties, co-forming all the characteristics of this compound.
Fluorine atoms have extremely high electronegativity, often lead to electron cloud migration in the molecule, reducing the electron cloud density of ortho and para-sites. This characteristic causes the distribution of electron clouds in the benzene ring to be abnormal, which in turn affects the electrophilic substitution reaction. Because fluorine atoms have a strong electron-absorbing induction effect, their conjugation effect is weak, so during the electrophilic substitution reaction, the reaction activity is lower than that of benzene, and the substitution is more inclined to the meso.
Although the electronegativity of iodine atoms is not as good as that of fluorine, its atomic radius is large and its polarizability is strong. In chemical reactions, iodine atoms can participate in many reactions by virtue of the deformability of their outer electron clouds. For example, when nucleophilic substitution reactions occur, iodine ions are more likely to leave, so that the molecule can be used as a nucleophilic substitution substrate under appropriate conditions.
Nitro is a strong electron-absorbing group, and its existence greatly reduces the electron cloud density of the benzene ring, significantly reduces the electron cloud density of the benzene ring, and enhances the polarity of the molecule. This not only affects the electrophilic substitution activity of the benzene ring, which greatly reduces its activity, but also in the reduction reaction, the nitro group can be reduced to other groups such as amino
In summary, the chemical properties of 1-fluoro-2-iodine-3-nitrobenzene are formed by the interaction of fluorine, iodine, nitro and benzene rings. Its characteristics in reactions such as electrophilic substitution, nucleophilic substitution and reduction depend on this unique structure, which makes it of important value and diverse applications in the field of organic synthesis.
What are 1-Fluoro-2-Iodo-3-Nitrobenzene synthesis methods?
The synthesis method of 1-fluoro-2-iodine-3-nitrobenzene is mostly derived from the inheritance of chemical technology and the research of various sages. One method is to start with benzene, first by nitrification, benzene is heated with concentrated nitric acid and concentrated sulfuric acid, and nitrobenzene can be obtained at an appropriate temperature. The nitrate is a strong blunt group, and then fluorine and iodine are introduced by halogenation. The introduction of fluorine is often reacted with fluorinated reagents, such as potassium fluoride, under specific solvents and conditions. The introduction of iodine can be coordinated by iodine elemental substance and appropriate oxidants, such as hydrogen peroxide, etc. After delicate regulation, it can reach 1-fluoro-2-iodine-3-nitrobenzene.
There are also other aromatic hydrocarbon derivatives as starters. For example, starting with o-fluoronitrobenzene, this target can be obtained by halogenation reaction, so that the iodine atom replaces the hydrogen at a specific position. During the halogenation reaction, it is crucial to choose the appropriate catalyst and reaction conditions. Or it is obtained by fluorination with o-iodonitrobenzene as the raw material. In the fluorination reaction, the properties of the solvent, the control of temperature, and the amount of fluorinating agent all affect the success or failure of the reaction and the yield.
Furthermore, the method of organic synthesis also depends on the emergence of new reagents and new technologies. In recent years, the technology of catalytic synthesis has improved day by day, and it may be possible to use efficient catalysts to optimize the reaction path, reduce the reaction steps, improve the reaction efficiency and selectivity, and make the synthesis of 1-fluoro-2-iodine-3-nitrobenzene more convenient and efficient. However, all synthesis methods require careful consideration of reaction conditions, purity of raw materials, and control of side reactions in order to achieve satisfactory results.
1-Fluoro-2-Iodo-3-Nitrobenzene to pay attention to when storing and transporting
1-Fluoro-2-iodine-3-nitrobenzene is also an organic compound. When storing and transporting, many matters must be paid attention to.
The first to bear the brunt, because of its chemical activity and poor stability, so the storage place must be dry and cool. Humid and high temperature environments can easily cause it to deteriorate or cause chemical reactions. If placed in a humid place, moisture may interact with the compound, causing structural changes and reducing its quality. Under high temperatures, molecular motion intensifies, which also increases the risk of reaction.
Furthermore, this compound is quite sensitive to light. Light may trigger photochemical reactions and change its chemical properties. When storing, it should be placed in a container protected from light, such as a brown glass bottle, to effectively block light and protect the stability of its chemical structure.
When transporting, safety protection is of paramount importance. Because it may be dangerous, the packaging must be strong and sealed. Suitable packaging materials should be selected to ensure that there is no leakage during transportation. Leakage will not only damage the goods, but also may endanger the transporting personnel and the surrounding environment.
In addition, this compound may react violently with other substances. When storing and transporting, it must never be mixed with oxidizing, reducing substances and alkaline substances. To prevent the occurrence of accidental chemical reactions, such as explosions, fires and other serious accidents.
In conclusion, the storage and transportation of 1-fluoro-2-iodine-3-nitrobenzene should be carried out under dry, cool and dark conditions, and the packaging should be sealed to avoid contact with incompatible substances, so as to ensure its safety and stability.