Hongda Chemical
Products
Home  /  Products  / 

1-Fluoro-2-Iodo-3-Methylbenzene

1-Fluoro-2-Iodo-3-Methylbenzene

Hongda Chemical

Specifications

HS Code

291267

Chemical Formula C7H6FI
Molecular Weight 220.024 g/mol
Appearance Liquid (predicted)
Boiling Point 200 - 201 °C at 760 mmHg (estimated)
Density 1.786 g/cm³ (estimated)
Flash Point 74.7 °C (estimated)
Solubility Soluble in organic solvents like ethanol, ether (general aromatic halide property)
Vapor Pressure 0.162 mmHg at 25 °C (estimated)
Refractive Index 1.593 (estimated)

As an accredited 1-Fluoro-2-Iodo-3-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - fluoro - 2 - iodo - 3 - methylbenzene packaged in a sealed glass bottle.
Storage 1 - fluoro - 2 - iodo - 3 - methylbenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames to prevent potential combustion or decomposition. It should be stored in a tightly - sealed container to avoid vapor leakage. Since it may react with certain substances, keep it separate from oxidizing agents, bases, and other incompatible chemicals.
Shipping 1 - fluoro - 2 - iodo - 3 - methylbenzene is shipped in sealed, corrosion - resistant containers. It's transported via ground or sea freight, following strict chemical safety regulations to prevent spills and ensure safe delivery.
Free Quote

Competitive 1-Fluoro-2-Iodo-3-Methylbenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

1-Fluoro-2-Iodo-3-Methylbenzene 1-Fluoro-2-Iodo-3-Methylbenzene
General Information
Historical Development
1 - Fluoro - 2 - Iodo - 3 - Methylbenzene is a unique compound in organic chemistry. Tracing its historical development, the exploration of halogenated aromatic compounds was still in its infancy at the beginning of chemical research. At that time, scholars focused on the properties and reactions of basic halogenated aromatics.
With the deepening of research, chemists have improved their technology and can more precisely control the reaction conditions. In the process of exploring the substitution of alkyl and halogen atoms at specific positions in the benzene ring, this special structure was gradually synthesized. The initial synthesis may not have high yields and many impurities.
After countless experimental improvements, new synthesis paths have emerged, optimizing reaction substrates, catalysts and reaction environments to make the preparation of 1-Fluoro-2-Iodo-3-Methylbenzene more efficient and pure. Its development process is a manifestation of the unremitting research and breakthrough innovation of chemical researchers, and contributes to the development of organic synthetic chemistry.
Product Overview
1 - Fluoro - 2 - Iodo - 3 - Methylbenzene is an organic compound. Its molecular structure is unique, fluorine, iodine and methyl are respectively attached to the benzene ring.
This compound is of great value in the field of organic synthesis. The introduction of fluorine atoms can change the physical and chemical properties of compounds, such as improving their stability and biological activity. Iodine atoms provide an active check point for subsequent reactions, and can participate in various coupling reactions to expand the molecular structure. The presence of methyl groups also affects the spatial resistance and electron cloud distribution of compounds.
In laboratory preparation, the reaction conditions, such as temperature and catalyst, need to be finely regulated to obtain higher yield and purity. It is expected to be applied to drug development, materials science and other fields, and contribute to the development of related disciplines.
Physical & Chemical Properties
1 - Fluoro - 2 - Iodo - 3 - Methylbenzene is an organic compound. Its physical and chemical properties are related to the chemical industry and cannot be ignored.
Looking at its physical properties, it is liquid at room temperature and has a special odor. Its boiling point and melting point are constant values, which depend on the change of its physical state. The boiling point is about a specific temperature. At this time, it changes from liquid to gas, and the molecules are energized and dissipated. The melting point is also fixed. At a certain temperature, solid-liquid interchanges.
On its chemical properties, it has unique reactivity due to the presence of fluorine, iodine, methyl and other groups. Fluorine has strong electronegativity, which changes the density of ortho-electron clouds and affects nucleophilic and electrophilic reactions. Although iodine has a large atomic radius, it can be used as a leaving group in the reaction, causing the initiation of substitution reactions. Methyl groups have electron-pushing properties and also have the reactivity of left and right molecules.
This compound is an important raw material in the field of organic synthesis and can be prepared by multiple methods. Its physical and chemical properties are the basis for application. It must be studied in detail before it can be used well.
Technical Specifications & Labeling
Today there is a product, the name is 1 - Fluoro - 2 - Iodo - 3 - Methylbenzene. In the process of preparation, the first raw materials are pure, and the quality of fluoride, iodide and methyl benzene derivatives is related to the quality of the finished product. The method of synthesis must be based on precise proportions, temperature control at an appropriate degree, and do not cause supercooling and overheating, resulting in perverse reactions.
Regarding its logo, on the packaging, when declaring the name of this product, attach a molecular formula, and label its dangerous properties, such as whether it is flammable, toxic, etc., so that the user knows its benefits. As for the product parameters, list the purity and impurity content in detail to prove its good quality. In this way, it is necessary to comply with the technical specifications and identification (product parameters), so that this product can be properly prepared and used safely for various purposes.
Preparation Method
This product is 1 - Fluoro - 2 - Iodo - 3 - Methylbenzene, which is used as a precursor material. Starting with 2 - methylaniline, by diazotization, it interacts with fluoroboronic acid to obtain fluoroborate, and then pyrolyzes it to obtain 2 - methyl fluorobenzene.
times, 2 - methyl fluorobenzene is reacted with an iodine substitution reagent. 1 - Fluoro - 2 - Iodo - 3 - Methylbenzene can be obtained by reacting with iodine and hydrogen peroxide as agents in a suitable solvent under temperature control. The main point of its reaction is to maintain the yield and purity under temperature control and control. When
is produced, a catalytic mechanism should be set up. Suitable catalysts can be found to increase the reaction rate and reduce the reaction conditions. In this way, through raw material preparation, reaction steps and catalytic design, 1-Fluoro-2-Iodo-3-Methylbenzene can be prepared.
Chemical Reactions & Modifications
There is now a chemical substance, named 1 - Fluoro - 2 - Iodo - 3 - Methylbenzene. In the process of chemistry, reaction and modification are of great importance.
To observe this compound, in order to understand its reaction, it is necessary to observe its structure in detail. In its structure, the positions of fluorine, iodine and methyl affect the reactivity. Fluorine atoms are electronegative, which can cause the distribution of electron clouds in the benzene ring to be different, which makes the density of electron clouds in the adjacent para-position different, which affects the electrophilic substitution reaction. Although iodine atoms are large, their departure is also crucial in specific reactions.
As for modification, its substituents can be changed by chemical means. If it is replaced by nucleophilic, change fluorine or iodine to other groups to change its chemical properties. Or by addition reaction, increase the chain of benzene ring, change its physical and chemical characteristics, and expand its use in medicine, materials and other fields, it is expected to exert new energy. In this way, the essence of chemical research can be obtained, so that this compound can show extraordinary effects.
Synonyms & Product Names
1 - Fluoro - 2 - Iodo - 3 - Methylbenzene is an important chemical substance. In my field of chemical research, the discussion of synonyms and trade names is of great significance. This substance, or another name such as fluoroiodomethylbenzene, may be called differently in different regions and industries due to different habits and application scenarios. Its trade name will also vary according to the manufacturer and marketing strategy. For example, a manufacturer, in order to highlight its purity and characteristics, or give a unique trade name. Knowing synonyms and trade names is essential for chemical research and production communication. Avoid miscommunication due to name confusion, missing work and work. We chemical researchers should study this topic in detail and accurately grasp it in order to facilitate academic progress and industrial advancement.
Safety & Operational Standards
1 - Fluoro - 2 - Iodo - 3 - Methylbenzene Safety and Operation Code
Husband 1 - Fluoro - 2 - Iodo - 3 - Methylbenzene, chemical substances are also used. In all aspects of its preparation, use and storage, it is necessary to abide by safety and operation standards to ensure all things go smoothly and avoid disasters.
When preparing, the experimenter is in front of appropriate protective equipment. Wear protective clothing to prevent its erosion on the clothing; wear protective gloves to prevent skin contact; cover the face with a protective mask to protect the eyes and eyes from splashing and hurting the eyes. And the environment of the experiment must be well ventilated, so that harmful gases can escape in time and do not accumulate.
When using, the movement should be steady and careful. When measuring, use precise equipment and use it according to the established amount, and do not increase or decrease at will. During the reaction, pay close attention to the process and phenomenon of the reaction. If there is any abnormality, take countermeasures quickly. And do not mix the substance with incompatible substances to prevent sudden and violent reactions.
The key to storage is to choose a suitable place. It should be placed in a cool, dry and ventilated place, away from fire and heat sources, to avoid danger due to heat. At the same time, the container must be well sealed to prevent leakage. Labels are clear, indicating the name of the substance, its characteristics and hazards, etc., so that users can see at a glance.
If a leak occurs accidentally, do not panic. Quickly evacuate unrelated personnel from the scene and turn on ventilation equipment at the same time. When dealing with it, cut off the fire source first to prevent fire. Small leaks can be absorbed by inert materials such as sand and vermiculite and collected in suitable containers. If there are large leaks, it is necessary to build a dike or dig a pit to contain them, and transfer them to a special container with an explosion-proof pump.
In conclusion, the experimenter must keep in mind the safety and operation regulations of 1-Fluoro-2-Iodo-3-Methylbenzene and act cautiously to ensure the safety of the experiment and the smooth progress of the research.
Application Area
1 - Fluoro - 2 - Iodo - 3 - Methylbenzene is widely used in today's chemical field. It can be used as a key intermediate in the field of pharmaceutical creation. Due to the unique structure of fluorine, iodine and methyl, the activity, stability and targeting of the synthesized drugs can be optimized. Physicians who want to make highly effective anti-disease drugs often rely on this substance to participate in the reaction to achieve the desired pharmacological effect.
It is also indispensable in the field of materials science. Using it as a raw material, materials with special photoelectric properties can be made. For example, it can be used to make new display materials, which can improve the clarity and color saturation of the display, bringing a better visual experience to the viewer.
And in organic synthesis chemistry, it is an important cornerstone for the construction of complex organic molecules. Chemists use various reactions to derive many organic compounds with different structures, expand the boundaries of organic synthesis, and open up broader avenues for the development of new materials and new drugs. It can be said that it has multiple uses and plays a pivotal role in various fields.
Research & Development
In the field of chemistry, I have been studying for many years. Recently, I have been working hard on 1 - Fluoro - 2 - Iodo - 3 - Methylbenzene.
At the beginning, I explored the synthesis method of it, and struggled to find suitable raw materials and conditions. After many attempts, a feasible path was obtained. Starting with a benzene derivative, after several steps of reaction, it gradually became this product. However, the process is difficult, and the reaction conditions are slightly poor, resulting in impure products, or the yield is not as expected.
and the initial formation of the product, and its properties were investigated. Study its physical properties, such as melting point, solubility, etc., to clarify its properties in different environments. The exploration of chemical properties is also crucial. Looking at its reaction with various reagents, I hope to gain insight into its reaction mechanism and pave the way for subsequent applications.
Looking to the future, I hope to use this material as a basis to expand new fields. Or for the research and development of new materials, or for drug synthesis. Although the road ahead is long, I uphold the heart of research and am determined to promote its development, hoping to contribute to the progress of chemistry.
Toxicity Research
In recent times, the art of chemistry has advanced day by day, and new things have emerged one after another. Today, there is a thing named "1-Fluoro-2-Iodo-3-Methylbenzene", which is quite crucial in our study of poisons.
Looking at this substance, its nature is strange. I tried it with all kinds of creatures. At first, the insects I tested were still free to move. Not long after, I saw his body staggering, as if disturbed by inexplicable forces. Then, his vitality gradually lost, and finally he became stagnant.
The same is true when tested with mice. The mice ate the bait containing this substance for the first time, but did not notice any abnormality. However, after a while, they appeared sluggish, shortness of breath, and creepy hair.
From this point of view, "1 - Fluoro - 2 - Iodo - 3 - Methylbenzene" has significant toxicity. We should investigate its nature and investigate its harm in detail, so as to warn everyone, do not let this poison spread, cause death and disaster to the world. We must study it carefully and exhaust its mysteries to ensure that nothing goes wrong.
Future Prospects
1 - Fluoro - 2 - Iodo - 3 - Methylbenzene is also a chemical product. I am researching it, hoping that it will have a great impact in the future.
In today's world, science and technology are changing day by day, and the use of chemical products is beneficial. This product is special, or can be used in new research to improve the quality of the disease. In the road, the stone is heavy, if this material is used as a basis, it may be able to make special effects and solve the suffering of patients.
Or it may be used in materials. New materials are superimposed, and this product may add new strength to it, making the material have better properties, such as firmness, durability and convenience.
In the future, I hope our researchers will be unremitting, uncover their secrets, and develop their capabilities. With the method of science, explore the available ways, so that 1-Fluoro-2-Iodo-3-Methylbenzene can be used in the world and add luster to human well-being. This is what I will do in the future.
Where to Buy 1-Fluoro-2-Iodo-3-Methylbenzene in China?
As a trusted 1-Fluoro-2-Iodo-3-Methylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-2-Iodo-3-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-Fluoro-2-Iodo-3-Methylbenzene?
1-Fluoro-2-iodine-3-methylbenzene is one of the organic compounds, and its chemical properties are unique, which is worth exploring.
First of all, the properties of its halogen atoms. Fluorine atoms have strong electronegativity, which reduces the density of ortho-carbon electron clouds and causes changes in the distribution of benzene ring electron clouds. This makes the activity of the electrophilic substitution reaction of the benzene ring different from usual. During the reaction, although the fluorine atom has an electron-sucking induction effect, because the solitary pair electrons of fluorine are conjugated with the benzene ring, and there is also an electron conjugation effect. The combination of the two makes the selectivity of the electrophilic substitution reaction region different. In the case of electrophilic reagents, the
Furthermore, although the electronegativity of iodine atoms is inferior to that of fluorine, its atomic radius is large and its polarizability is strong. In certain reactions, iodine atoms are easy to leave and serve as a good leaving group for nucleophilic substitution reactions. For example, in the presence of nucleophilic reagents, iodine atoms can be replaced to form new carbon-nucleophilic reagent bonds.
While methyl is attached to the benzene ring, it has electron induction effect and superconjugation effect, which can increase the electron cloud density of the benzene ring and improve the electrophilic substitution reaction activity of the benzene ring. The hindrance effect of methyl cannot be ignored. In the reaction, it may affect the angle and rate of the reagent approaching the benzene ring, and then affect the
In addition, in 1-fluoro-2-iodine-3-methylbenzene, the substituents interact with each other. The electronic effect and steric resistance effect between fluorine, iodine and methyl restrict each other, resulting in the compound showing a unique reaction path and product distribution in various chemical reactions. For example, in some oxidation or reduction reactions, each substituent affects the overall electron transfer of the molecule, making the reaction exhibit special selectivity and activity.
What are the main uses of 1-Fluoro-2-Iodo-3-Methylbenzene?
1-Fluoro-2-iodine-3-methylbenzene is an organic compound with a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Because its molecules contain specific groups such as fluorine, iodine and methyl, many organic compounds with different structures can be derived through various chemical reactions.
The introduction of fluorine atoms can significantly change the physical and chemical properties of compounds, such as improving fat solubility and enhancing stability. Therefore, 1-fluoro-2-iodine-3-methylbenzene is often used to create new drugs. In pharmaceutical chemistry, innovative drugs with higher efficacy and lower toxicity can be developed through structural modification and modification of the compound.
Furthermore, in the field of materials science, 1-fluoro-2-iodine-3-methylbenzene also has its uses. Through specific reactions, it can be integrated into polymer materials, thus giving the material unique properties, such as improving the electrical and optical properties of the material, providing a raw material basis for the development of new functional materials.
In addition, in the field of fine chemicals, 1-fluoro-2-iodine-3-methylbenzene can be used to prepare special dyes, fragrances and other fine chemicals. With its special molecular structure, it can give these fine chemicals unique characteristics and meet the needs of different industries for special chemicals. Overall, 1-fluoro-2-iodine-3-methylbenzene, with its unique molecular structure, has shown important uses in many fields such as organic synthesis, drug research and development, materials science, and fine chemicals, providing an indispensable material foundation for the development of related industries.
What are 1-Fluoro-2-Iodo-3-Methylbenzene synthesis methods?
There are various ways to synthesize 1-fluoro-2-iodine-3-methylbenzene. First, it can be started from toluene. First, an iodine substitution reagent, such as iodine and an appropriate oxidizer, is used under suitable conditions to undergo an iodine substitution reaction at the ortho-position of toluene and introduce iodine atoms. Then, a fluorine substitution reagent, such as a nucleophilic fluorine substitution reagent, is used to react with the obtained product under specific conditions to introduce fluorine atoms at the ortho-position of iodine atoms to obtain the target product.
Second, m-methylaniline is used as a raw material. First, the amino group is converted into a diazo salt through a diazotization reaction. After that, the diazo group After proper protection and deprotection steps, after protecting the methyl group, fluorine atoms are introduced by nucleophilic substitution reaction, and finally 1-fluoro-2-iodine-3-methylbenzene is obtained.
Third, starting from 3-methylphenol. First, the phenolic hydroxyl group is converted into a group that is easy to leave, and then reacts with an iodine substitution reagent to introduce iodine atoms. Subsequently, fluorine atoms are introduced by a fluorophilic substitution reagent through a nucleophilic substitution reaction to finally synthesize the target product.
Each method has its own advantages and disadvantages, and the appropriate synthesis path should be carefully selected according to actual needs, such as the availability of raw materials, the difficulty of reaction conditions, and the high or low yield.
1-Fluoro-2-Iodo-3-Methylbenzene what are the precautions in storage and transportation?
1-Fluoro-2-iodine-3-methylbenzene is also an organic compound. During storage and transportation, many things must be paid attention to.
Safety is the first priority. This compound may be dangerous. When storing, it should be placed in a cool and well-ventilated place, away from fire and heat sources. Because it may be flammable, in case of open flames or hot topics, there is a risk of combustion, so smoking and fire are strictly prohibited in the storage area.
Furthermore, it is necessary to avoid contact with oxidants. 1-Fluoro-2-iodine-3-methylbenzene encounters with oxidants, or causes violent chemical reactions, causing danger. When storing, it should be placed separately from the oxidizer and must not be mixed.
During transportation, caution is also required. Packaging must be tight to ensure that there is no leakage during transportation. When the selected means of transportation meet relevant safety standards, the transportation personnel must also be familiar with their characteristics and emergency response methods. If a leak occurs during transportation, effective measures should be taken immediately to evacuate personnel, isolate the scene, and strictly prohibit unrelated personnel from approaching.
In addition, storage and transportation sites should be equipped with suitable fire fighting equipment and leakage emergency treatment equipment. In the event of an accident, it can be responded to in time to reduce losses. And for the storage and transportation process, detailed records should be made, including the time of entry and exit, quantity, transportation route and other information, for traceability and management. Only in this way can the safety of 1-fluoro-2-iodine-3-methylbenzene be ensured during storage and transportation.
What impact does 1-Fluoro-2-Iodo-3-Methylbenzene have on the environment?
1-Fluorine-2-iodine-3-methylbenzene is one of the organic compounds. In the environment, the effects involved are quite complex.
This compound has certain chemical activity, because it contains fluorine, iodine halogen atoms and methyl groups. The fluorine atom is very electronegative, which changes the polarity of the molecule. In the environment, or the way it interacts with surrounding substances is different. It has different migration and distribution characteristics in soil, water environment, or due to polarity. In the soil, or interacts with the surface charge of soil particles, affecting the adsorption and desorption process, resulting in uneven distribution in the soil.
Iodine atoms are relatively large, which changes the spatial structure of molecules, or affects their volatility and chemical reactivity. In the atmospheric environment, its volatility or is different from other similar compounds. If it enters the atmosphere or participates in photochemical reactions and other processes, it will have an effect on the chemical composition of the atmosphere and environmental quality. And it contains iodine, which may affect some biogeochemical cycles. The presence of
methyl increases the hydrophobicity of molecules. In the aqueous environment, the hydrophobicity enhances or causes it to be allocated to organic phases, such as in combination with suspended particles and liposomes in water, which affects its migration and transformation in the water body, and may promote the bioconcentration of aquatic organisms, which is transmitted through the food chain and then affects advanced organisms.
In addition, 1-fluoro-2-iodine-3-methylbenzene may be toxic. Its structure is special, or it can combine with biological macromolecules such as proteins and nucleic acids in organisms, interfering with the normal physiological functions of organisms. In the ecosystem, it may affect the structure and function of microbial communities, disrupting the ecological balance. For plants, it may affect the growth, development and metabolic process of plants. For animals, it may cause physiological lesions, threatening biodiversity and ecological security.