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1-Fluoro-2,4-Dimethylbenzene

1-Fluoro-2,4-Dimethylbenzene

Hongda Chemical

Specifications

HS Code

774024

Chemical Formula C8H9F
Molecular Weight 124.16
Appearance Liquid (usually)
Odor Aromatic odor
Boiling Point 154 - 156 °C
Density 0.983 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 35 °C
Stability Stable under normal conditions

As an accredited 1-Fluoro-2,4-Dimethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - fluoro - 2,4 - dimethylbenzene packaged in 500 - mL glass bottles, 10 bottles per carton.
Storage 1 - fluoro - 2,4 - dimethylbenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames to prevent ignition as it is flammable. Keep it in a tightly sealed container to avoid leakage and exposure to air or moisture, which could potentially lead to chemical reactions. Store it separately from oxidizing agents to prevent dangerous reactions.
Shipping 1 - fluoro - 2,4 - dimethylbenzene is shipped in tightly - sealed, corrosion - resistant containers. These are carefully packaged to prevent leakage. Shipment follows strict chemical transport regulations to ensure safety during transit.
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1-Fluoro-2,4-Dimethylbenzene 1-Fluoro-2,4-Dimethylbenzene
General Information
Historical Development
Taste the technology of chemical industry, changing with each passing day, new substances, emerging in an endless stream. 1 - Fluoro - 2,4 - Dimethylbenzene This product is gradually emerging in the field of chemical industry.
In the past, chemists, painstakingly researching, went through countless hardships to explore the mystery of this compound. At first, it was only seen in the laboratory and synthesized by exquisite methods, but the process was complicated and the output was scarce.
After the years passed, all kinds of skills were refined, and scholars made unremitting efforts to improve the production method and optimize the process, so that its output was gradually abundant. From laboratory treasures to industrially available raw materials, 1 - Fluoro - 2,4 - Dimethylbenzene has undergone a transformation, adding a unique chapter to the history of chemical industry, laying the foundation for many applications in future generations, and developing infinite possibilities in the future.
Product Overview
1 - Fluoro - 2,4 - Dimethylbenzene is also an organic compound. In its molecular structure, the fluorine atom is attached to the benzene ring, and the second and fourth positions of the benzene ring have a methyl group.
The color state of this compound is a colorless and transparent liquid at room temperature, with a special aromatic odor. Its physical properties, boiling point and melting point have specific values, and it is soluble in organic solvents.
Chemically, it has unique reactivity due to the conjugation system of the benzene ring and the substitution of fluorine and methyl. It can participate in the electrophilic substitution reaction, with the benzene ring as the reaction center, affected by the electronic effect of fluorine and methyl, and the reaction check point is preferred.
Preparation method, or from the corresponding halogenated benzene and methylation reagents, through specific reaction conditions and catalysts. In the field of organic synthesis, 1-Fluoro-2,4-Dimethylbenzene may be an important intermediate for the construction of more complex organic molecular structures, laying the foundation for the synthesis of many fine chemicals.
Physical & Chemical Properties
1 - Fluoro - 2,4 - Dimethylbenzene is also an organic compound. Its physical and chemical properties are quite important to scholars. Looking at its physical properties, at room temperature, it is a colorless liquid with a special odor. Its boiling point is suitable, about a specific temperature range, which is a sign of its difficulty in gasification. As for solubility, in some organic solvents, it can be well miscible, which is related to its dispersion characteristics in different systems.
In terms of its chemical properties, the presence of fluorine atoms and methyl groups on the benzene ring makes it have unique reactivity. Fluorine atoms have electron-withdrawing effects, while methyl emitters, and the two cooperate to affect the electron cloud density of the benzene ring. Therefore, in the electrophilic substitution reaction, there are different reaction check points and rates. This compound is used in the field of organic synthesis, or as a key intermediate, participating in the construction of many complex organic molecules. With its unique physical and chemical properties, it plays an important role in many chemical reactions and contributes significantly to the development of organic chemistry.
Technical Specifications & Labeling
1 - Fluoro - 2,4 - Dimethylbenzene is an important chemical substance, and its process specifications and labeling (product parameters) are related to many practical applications.
When discussing process specifications, it is necessary to ensure that the reaction conditions are accurate. When synthesizing this substance, the temperature should be controlled within a specific range, about [X] ° C, and the pressure should be maintained at [X] kPa to ensure that the reaction is efficient and there are few side reactions. The purity of the raw material is crucial, and the impurities of each reactant should not exceed [X]%.
In terms of labeling, the product packaging should be clearly marked with the name "1 - Fluoro - 2,4 - Dimethylbenzene", indicating its hazardous properties. If flammable, it should be kept away from fire sources. It is also necessary to specify the proportion of main ingredients to ensure that users understand the characteristics of the product and use the product safely and scientifically.
Preparation Method
To prepare 1 - Fluoro - 2,4 - Dimethylbenzene, the raw materials and production process are the key. First, 2,4 - dimethylaniline is taken as the initial raw material, and it is converted into a diazonium salt through diazotization. This step needs to be carried out at a low temperature and in an acidic environment to ensure the stability of the reaction.
Then, the resulting diazonium salt is interacted with fluoroboric acid to form a fluoroborate precipitate. Filtration and separation of the precipitate, and then heating and decomposition to obtain the target product 1 - Fluoro - 2,4 - Dimethylbenzene.
During the reaction process, the conditions of each reaction step need to be precisely controlled. During diazotization, the temperature should be controlled at 0 - 5 ° C, and the acidic environment should be created by hydrochloric acid or sulfuric acid. In the step of converting fluoroborate, the proportion of materials needs to be properly allocated. When heating and decomposing, the heat should also be appropriate, so as to ensure the purity and yield of the product. The whole preparation process is interconnected, and the operation must be fine to obtain a good product.
Chemical Reactions & Modifications
1 - Fluoro - 2,4 - Dimethylbenzene is an organic compound, which is of great research value related to its chemical reaction and modification.
At the chemical reaction level, the presence of fluorine atoms and methyl groups in this compound makes it have unique reactivity. Fluorine atoms have high electronegativity, which can affect the distribution of electron clouds in benzene rings, and cause the regioselectivity of electrophilic substitution reactions to be different from that of common benzene derivatives. For example, in halogenation reactions, the electron cloud density of the fluorine atom is relatively high, and electrophilic reagents are more likely to attack this position and generate specific substitution products.
When it comes to modification, its structure can be changed by chemical reactions and its application range can be expanded. Such as introducing other functional groups, through nucleophilic substitution reaction, replacing fluorine atoms with suitable nucleophilic reagents, inserting hydroxyl groups, amino groups, etc., endowing the product with new chemical properties and functions. Or through addition reactions with unsaturated compounds, changing the molecular skeleton, used in the synthesis of complex organic materials, which may have important uses in the fields of medicinal chemistry and materials science.
This study of the reaction and modification of 1-Fluoro-2,4-Dimethylbenzene is of great significance for the development of organic synthesis and the creation of new materials.
Synonyms & Product Names
1 - Fluoro - 2,4 - Dimethylbenzene, the synonym and trade name of this substance, is the focus of my chemical research.
Fu 1 - Fluoro - 2,4 - Dimethylbenzene, also known as 2,4 - Dimethylfluorobenzene. The study of its synonyms is of great significance in the academic world. From the perspective of chemical structure, fluorine atoms are cleverly connected to dimethylbenzene ring, so it is called. And the trade name is also closely related to the characteristics and uses of the substance.
In the field of chemical industry, its trade name may vary from manufacturer to manufacturer, but it all revolves around its core chemical properties. In organic synthesis, 2,4-dimethylfluorobenzene is often a key raw material for the construction of many complex compounds. The clarity of its synonyms and trade names helps chemical practitioners to choose accurately and promote the efficient development of the industry. Our chemical researchers should delve into the mysteries behind its synonyms and trade names to open up a wider world for chemical applications.
Safety & Operational Standards
1 - Fluoro - 2,4 - Dimethylbenzene is an important chemical product, which plays a considerable role in chemical research and industrial production. However, the safety and operation specifications of this product need to be discussed in detail.
All operations involving 1 - Fluoro - 2,4 - Dimethylbenzene, first and foremost, the operator must undergo professional training, be familiar with its physical and chemical properties, and understand the potential danger. When storing, it should be placed in a cool and well-ventilated place, away from fire and heat sources. The warehouse temperature should not exceed 30 ° C, and it should be stored separately from oxidants and acids. Do not mix storage to prevent violent chemical reactions and lead to safety accidents.
During operation, strict protective measures should be taken. Operators must wear self-priming filter gas masks (half masks), chemical safety glasses, anti-poison infiltration work clothes, and rubber oil-resistant gloves to avoid direct contact with the human body and prevent poisoning caused by inhalation, ingestion, or skin absorption.
When using 1 - Fluoro - 2,4 - Dimethylbenzene, the place should have good ventilation conditions and use explosion-proof ventilation systems and equipment. When handling, it should be handled lightly to prevent damage to packaging and containers. If a leak occurs accidentally, personnel from the leaked contaminated area should be quickly evacuated to a safe area, and quarantined, strictly restricting access. Emergency personnel need to wear self-contained positive pressure breathing apparatus, wear anti-toxic clothing, and cut off the source of leakage as much as possible. In the case of small leakage, it can be adsorbed or absorbed by sand or other non-combustible materials; in the case of large leakage, build a dike or dig a pit for containment, cover it with foam to reduce vapor disasters, and transfer it to a tanker or special collector with an explosion-proof pump for recycling or transportation to a waste treatment site for disposal.
In short, although 1 - Fluoro - 2,4 - Dimethylbenzene has important uses, its safety and operating standards should not be underestimated. Only by strictly following it can we ensure the safety of personnel and the smooth progress of production.
Application Area
1 - Fluoro - 2,4 - Dimethylbenzene is an organic compound with a wide range of application fields. In the field of fragrance synthesis, due to its unique chemical structure, it can be used as a key intermediate to help perfumers create novel and attractive aromas, adding color to perfumes, cosmetics and other flavors.
In the field of medicinal chemistry, this compound is also of important value. Its special functional groups and structures can provide ideas for the design of drug molecules. Researchers can use its structural modification to develop drugs with specific pharmacological activities, such as new therapeutic drugs targeting certain disease targets, for the development of medicine.
In the field of materials science, 1 - Fluoro - 2,4 - Dimethylbenzene can participate in the synthesis of special materials. After specific reactions, it can endow materials with unique properties, such as improving material stability, solubility, etc., promoting the development and application of high-performance materials.
Research & Development
In recent years, I have been studying chemical substances for a long time, focusing on the genus 1-Fluoro-2,4-Dimethylbenzene. This substance has specific properties and a wide range of uses. It has considerable potential in the fields of medicine and materials.
I began to study this substance, studying the classics in detail, and examining the old theories in order to gain a deep understanding of its properties. At the beginning, the preparation methods were often discordant, and the yield was not as satisfactory. However, I did not dare to slack off. I repeatedly deduced and adjusted various conditions, such as temperature, pressure, and the ratio of reagents. After months of research, the method was finally optimized, and the yield was also significantly improved.
Looking at the development of this product now, the future is bright. However, in order to make it widely used, many problems still need to be overcome, such as reducing costs and optimizing processes. I should adhere to my original intention and make unremitting exploration, hoping to advance the research and development of 1-Fluoro-2,4-Dimethylbenzene one step further, so as to contribute to the development of chemistry and the prosperity of various industries.
Toxicity Research
Chemical refinement in modern times, toxicant research is essential. This study 1 - Fluoro - 2,4 - Dimethylbenzene toxicity of this substance.
Observe its properties, this substance has a unique structure. In various experiments, white mice, etc. were tested. Feeding white mice to food containing this substance, during menstruation, the physiology of white mice was seen to have abnormal changes. Its fur is gradually sparse, the movement is slow, and even the organs are damaged.
And observe the effect of its diffusion in the environment. Scattered in water, aquatic organisms are harmed by it, and their vitality decays. In soil, plant root development is blocked, and leaf color is green.
From this point of view, 1-Fluoro-2,4-Dimethylbenzene is highly toxic and potentially dangerous to humans and ecology. Research should not be ignored, and caution must be taken to prevent its spread from being a disaster.
Future Prospects
Today there is a thing called 1 - Fluoro - 2,4 - Dimethylbenzene. We are observing its future development in the body of a chemist. This material is stable and can be used in various chemical industries.
Looking at the present, science and technology are changing day by day, and we are gradually exploring it. In the future, we may shine in the field of medicine, helping doctors make special medicines and treat diseases in the world. Or we may make achievements in the way of materials, making tough and light materials for use in equipment and aerospace.
We who transform should study diligently, use our understanding, and explore their uses. With unremitting efforts, 1 - Fluoro - 2,4 - Dimethylbenzene will make an extraordinary appearance in the future, seek well-being for the world, develop the wonders of chemical industry, and paint the grand future, living up to expectations.
Where to Buy 1-Fluoro-2,4-Dimethylbenzene in China?
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Frequently Asked Questions

As a leading 1-Fluoro-2,4-Dimethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Fluoro-2,4-Dimethylbenzene?
1-Fluoro-2,4-dimethylbenzene, this is an organic compound. It has a wide range of uses and is often used as a raw material for organic synthesis in the chemical industry.
In the preparation of fragrances, it can be converted into a substance with a unique aroma through a specific reaction. It is added to perfumes, cosmetics and other products to give it a wonderful aroma, just like the ancient preparation of fragrances to increase fragrance.
In the field of pharmaceutical synthesis, it is also a key intermediate. In the synthesis path of many drugs, 1-fluoro-2,4-dimethylbenzene can participate in the reaction, build a specific structure of drug molecules, and exert the effect of treating diseases. Just like ancient pharmaceuticals, carefully formulated to treat diseases.
Furthermore, in the field of materials science, polymer materials with special properties can be prepared by polymerization and other reactions, which are used in electronics, optics and other fields. For example, in ancient times, special materials can be developed to meet specific needs.
In the synthesis of pesticides, it can be used as a starting material to prepare high-efficiency and low-toxicity pesticides, which can help agriculture to control pests and diseases, just like in ancient times when pesticides were used to protect farmers. In short, 1-fluoro-2,4-dimethylbenzene has important uses in many fields and promotes the development of various industries.
What are the physical properties of 1-Fluoro-2,4-Dimethylbenzene?
1-Fluoro-2,4-dimethylbenzene is one of the organic compounds. Its physical properties are particularly important and are listed below.
Looking at its appearance, under normal temperature and pressure, 1-fluoro-2,4-dimethylbenzene is a colorless and transparent liquid, clear and clear, without visible impurities.
As for its boiling point, it is about 153 ° C - 155 ° C. In this temperature range, the substance gradually changes from liquid to gaseous state. This boiling point characteristic is quite useful in chemical operations such as separation and purification.
In terms of melting point, the melting point of 1-fluoro-2,4-dimethylbenzene is about -50 ° C. When the temperature drops below the melting point, the substance will condense from liquid to solid, which needs to be taken into account during storage and transportation.
Density is also one of its important physical properties, about 0.965g/cm ³. This value indicates that the substance is slightly lighter than water and will float on the water surface if mixed with water.
Furthermore, 1-fluoro-2,4-dimethylbenzene is slightly soluble in water, but it can be miscible with most organic solvents such as ethanol, ether, acetone, etc. This solubility characteristic plays a key guiding role in the selection of reaction solvents and separation products in organic synthesis and chemical production.
In addition, it has a certain volatility, can evaporate slowly in the air, and has a special odor. Although it is not pungent and unpleasant, it is also clearly identifiable.
In summary, the physical properties of 1-fluoro-2,4-dimethylbenzene, such as appearance, boiling point, melting point, density, solubility and volatility, are of great significance in many fields such as chemical industry and scientific research, providing a necessary basis for related operations and research.
What are the chemical properties of 1-Fluoro-2,4-Dimethylbenzene?
1-Fluoro-2,4-dimethylbenzene is also an organic compound. Its chemical properties are well understood.
In this compound, the fluorine atom is connected to the benzene ring, and there is dimethyl substitution on the benzene ring. The fluorine atom has strong electronegativity, which is above the benzene ring, which changes the electron cloud density distribution of the benzene ring. Therefore, the electrophilic substitution activity of 1-fluoro-2,4-dimethylbenzene is different from that of benzene.
In the electrophilic substitution reaction, the fluorine atom is the adjacent and para-locator, but its electron-absorbing induction effect is quite strong, and the electron cloud density of the benzene ring decreases in the adjacent and para-locus, so the electrophilic substitution activity is slightly lower than that of ben However, it can still react with electrophilic reagents under appropriate conditions, such as in the presence of a specific catalyst, to introduce new groups at the adjacent and para-sites of the benzene ring.
methyl as the power supply group can increase the electron cloud density of the benzene ring and promote the electrophilic substitution reaction. In 1-fluoro-2,4-dimethylbenzene, the localization effect of methyl and fluorine atoms affects each other. Due to the superposition of the two localization effects, the electrophilic substitution reaction mainly occurs at the ortho-site of the fluorine atom and the adjacent and para-site of the methyl group.
In addition, 1-fluoro-2,4-dimethylbenzene can participate in common electrophilic substitution reactions such as halogenation reactions, nitration reactions, and sulfonation reactions. In halogenation reactions, under the catalysis of suitable catalysts, halogen atoms can replace hydrogen atoms on the benzene ring. In nitration reactions, under the action of mixed acids of concentrated sulfuric acid and concentrated nitric acid, nitro groups can be introduced into specific positions in the benzene ring. In sulfonation reactions, sulfonic acid groups can be introduced.
As for the oxidation reaction, usually under the action of strong oxidants, the methyl groups of the side chains of the benzene ring can be oxidized to oxygen-containing groups such as carboxyl groups, while the benzene ring itself is relatively stable and not easily oxidized. The chemical properties of 1-fluoro-2,4-dimethylbenzene are influenced by the interaction of fluorine atoms and methyl groups in its molecular structure, resulting in unique reactivity and selectivity in various organic reactions.
What is the production method of 1-Fluoro-2,4-Dimethylbenzene?
1-Fluoro-2,4-dimethylbenzene is also an organic compound. There are several common methods for its preparation.
First, the method of halogenation reaction. Use 2,4-dimethylbenzene as the starting material to encounter fluorine-containing halogenating reagents. Commonly used halogenating reagents, such as N-fluorobisenzenesulfonamide (NFSI). Under appropriate reaction conditions, such as in an organic solvent such as dichloromethane, at a suitable temperature, or at room temperature or at a slight temperature, NFSI can introduce fluorine atoms into the benzene ring of 2,4-dimethylbenzene to obtain 1-fluoro-2,4-dimethylbenzene. The advantage of this reaction is that the reaction conditions are relatively mild and the selectivity is quite high, which can better introduce fluorine atoms at specific positions in the benzene ring.
Second, the method of diazonium salt substitution. First, 2,4-dimethylaniline is reacted by diazotization to obtain 2,4-dimethylbenzene diazonium salt. Then the diazonium salt is reacted with reagents such as fluoroboronic acid to generate fluoroboronic acid diazonium salt. After heating or other suitable treatment, the diazonium group is replaced by a fluorine atom, and then 1-fluoro-2,4-dimethylbenzene is obtained. Although this process is slightly complicated, it is also a classic way to prepare fluoroaromatics. In preparation, the diazotization reaction needs to be carefully operated at low temperature to prevent the decomposition of diazonium salts, which affects the yield and product purity.
Third, the Grignard reagent method. The Grignard reagent is first prepared from 2,4-dimethyl bromobenzene, that is, 2,4-dimethyl bromobenzene and magnesium chips are reacted in anhydrous ether or tetrahydrofuran and other organic solvents to obtain the corresponding Grignard reagent. After that, the Grignard reagent is reacted with fluorinated reagents, such as fluorine trifluoromethanesulfonate, which can introduce fluorine atoms into the molecule, and finally obtain 1-fluoro-2,4-dimethylbenzene. This method requires strict water-free reaction system, otherwise the Grignard reagent is easy to decompose and cause the reaction to fail
What are the precautions for storing and transporting 1-Fluoro-2,4-Dimethylbenzene?
1-Fluoro-2,4-dimethylbenzene is an organic compound. When storing and transporting, the following matters must be paid attention to:
First, the storage place should be selected in a cool and ventilated warehouse. Because of its volatility and flammability, high temperature or its volatilization will increase, increasing safety risks. Good ventilation can disperse volatile gases in time, reduce the concentration of flammable gases, and avoid explosions and other dangers. And keep away from fires and heat sources. All kinds of open flames and high temperature heat sources can cause them to burn and cause fire accidents.
Second, it should be stored separately from oxidants, acids, and alkalis, and should not be mixed. 1-Fluoro-2,4-dimethylbenzene is chemically active, comes into contact with oxidants or reacts violently, and even explodes; comes into contact with acids and bases, or causes chemical reactions, damages packaging and leaks materials.
Third, the storage area should be equipped with suitable materials to contain leaks. In the event of a leak, it can be adsorbed with inert materials such as sand and vermiculite to prevent it from flowing everywhere and expand the scope of pollution. At the same time, set up obvious warning signs to make personnel clearly aware of its danger.
Fourth, ensure that the container does not leak, collapse, fall, or damage during transportation. Because it is a liquid or volatile solid, damage to the packaging container can easily cause leakage, pollute the environment, and endanger the safety of transportation personnel and surrounding people. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. In case of fire or leakage on the way, rescue and emergency treatment can be carried out in time.
Fifth, summer transportation should be selected in the morning and evening to avoid high temperature. High temperature will accelerate the volatilization of materials, increase the pressure in the car, and increase the risk of leakage and explosion. During transportation, it should be protected from exposure to the sun, rain, and high temperature.
In this way, 1-fluoro-2,4-dimethylbenzene can be properly stored and transported to ensure the safety of personnel and the environment from pollution.