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1-Fluoro-2,4-Dibromobenzene

1-Fluoro-2,4-Dibromobenzene

Hongda Chemical

Specifications

HS Code

700725

Chemical Formula C6H3Br2F
Molar Mass 255.896 g/mol
Appearance Solid (usually white to off - white)
Melting Point 45 - 47 °C
Boiling Point 230 - 232 °C
Solubility In Water Insoluble (organic compound with non - polar aromatic ring and halogens)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, benzene
Vapor Pressure Low (due to its relatively high molar mass and solid state at room temperature)

As an accredited 1-Fluoro-2,4-Dibromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - fluoro - 2,4 - dibromobenzene packaged in a sealed glass bottle.
Storage 1 - fluoro - 2,4 - dibromobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames as it is likely flammable. Keep it in a tightly sealed container to prevent leakage and exposure to air or moisture, which could potentially cause decomposition. Store it separately from oxidizing agents and reactive chemicals to avoid dangerous reactions.
Shipping 1 - fluoro - 2,4 - dibromobenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring secure transit to prevent leakage and environmental or safety risks.
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1-Fluoro-2,4-Dibromobenzene 1-Fluoro-2,4-Dibromobenzene
General Information
Historical Development
1 - Fluoro - 2,4 - Dibromobenzene is also an organic compound. Tracing its historical evolution, organic chemistry flourished at an early age, and many sages worked hard to explore the structure and synthesis of substances. The initial appearance of this compound was repeatedly studied by scholars in the laboratory, in order to obtain new substances to expand the field of chemistry.
At that time, the experimental method was still simple, but the ancestors tried unremitting with perseverance. After countless reactions, adjustments, and changes in conditions, this 1 - Fluoro - 2,4 - Dibromobenzene was finally obtained. With the passage of time, chemical techniques became more and more exquisite, instruments became more accurate, and the synthesis method was gradually improved, with improved yield and better purity. From its initial difficult search to its current maturity, this compound has witnessed the development of chemical history and laid an important foundation for many subsequent studies and applications.
Product Overview
1 - Fluoro - 2,4 - Dibromobenzene is also an organic compound. In its molecular structure, the fluorine atom is one of the benzene ring, and the dibromo atom is separated into two and four positions.
The properties of this compound are mostly solid at room temperature, with a nearly white and slightly yellow color and a special odor. The melting point is about XX ° C, and the boiling point is XX ° C. It is soluble in organic solvents such as ethanol and ether, but insoluble in water.
The preparation method is mostly obtained from specific benzene derivatives through halogenation. During the reaction, temperature control, time control and catalyst selection are required to achieve high yield and excellent purity.
1 - Fluoro - 2,4 - Dibromobenzene is widely used in the field of organic synthesis. It can be used as an intermediate for the preparation of many drugs, pesticides and functional materials. It is also an important raw material for chemical research and industrial production.
Physical & Chemical Properties
1 - Fluoro - 2,4 - Dibromobenzene is an important chemical substance. Its physical and chemical properties are unique and worthy of study.
Looking at its physical properties, at room temperature, this substance has a specific color state. Its melting point and boiling point are also key parameters to characterize its properties. The melting point is the critical temperature at which the substance transitions from solid to liquid; the boiling point is the key node for the transition from liquid to gaseous. These two are of great significance when studying the phase transition and purification process of the substance.
In terms of chemical properties, the presence of fluorine and bromine atoms in 1 - Fluoro - 2,4 - Dibromobenzene gives it unique reactivity. Fluorine atoms have high electronegativity, while bromine atoms affect the nucleophilic substitution of molecules. In the field of organic synthesis, it can be used as a key intermediate to participate in many chemical reactions, such as arylation reactions, to construct more complex organic molecular structures. Studying its physical and chemical properties can lay a solid foundation for related industrial production and scientific research applications.
Technical Specifications & Labeling
1 - Fluoro - 2,4 - Dibromobenzene is an important raw material for organic synthesis, and its preparation process and quality standards are crucial.
In terms of process specifications, benzene is used as the starting material, and the bromination reaction is first carried out. Under the action of a specific temperature and catalyst, the amount of brominating agent is precisely regulated, so that bromine atoms are introduced into a specific position of the benzene ring to form dibromobenzene intermediates. Subsequently, the fluorination reagents are carefully selected, and the fluorination reaction is carried out under suitable reaction conditions. The fluorine atoms are successfully introduced to obtain 1 - Fluoro - 2,4 - Dibromobenzene. The reaction process must strictly control parameters such as temperature, pressure and reaction time to ensure the efficient and accurate reaction.
On the product logo (product parameters), its appearance should appear as a colorless to light yellow liquid with a weak and characteristic smell. The purity should be above 99% and the impurity content should be minimal. Physical parameters such as boiling point, melting point, and density should conform to the established range to ensure stable product quality. In this way, it can meet the needs of different fields for 1-Fluoro-2,4-Dibromobenzene and play a key role in organic synthesis and other fields.
Preparation Method
To prepare 1-Fluoro-2,4-Dibromobenzene, the raw materials, production process, reaction steps and catalytic mechanism are as follows. First, an appropriate amount of benzene is taken, and iron bromide is used as a catalyst to react with bromine to obtain 1,3-dibromobenzene. In this reaction, iron bromide promotes the polarization of bromine molecules, enhances its electrophilicity, and facilitates the electrophilic substitution of benzene rings. Then, 1,3-dibromobenzene is reacted with fluorinated reagents under specific solvents and heating conditions. Fluoride ions in the fluorinated reagents are nucleophilically substituted to replace specific bromine atoms on the benzene ring, thereby preparing 1-Fluoro-2,4-Dibromobenzene. This reaction process requires strict control of the reaction temperature, time and proportion of raw materials to ensure product purity and yield.
Chemical Reactions & Modifications
1 - Fluoro - 2,4 - Dibromobenzene is an important compound in organic synthesis. In chemical research, its chemical reaction and modification are of great concern.
Looking at its chemical reactions, nucleophilic substitution reactions are quite common. Due to the activity of halogen atoms on the benzene ring, it can interact with many nucleophilic reagents. For example, when encountering hydroxyl negative ions, substitution can occur, and fluorine or bromine atoms are replaced by hydroxyl groups to form benzene derivatives containing hydroxyl groups. Control of this reaction condition is crucial, and factors such as temperature and solvent affect the reaction rate and yield.
When it comes to modification, different substituents can be introduced to change their physical and chemical properties. If alkyl is introduced, it can increase its fat solubility, and its performance can be optimized according to specific needs in the field of drug development or materials science. Through the delicate design of chemical reactions and modification methods, 1-Fluoro-2,4-Dibromobenzene will demonstrate extraordinary potential in more fields.
Synonyms & Product Names
1 - Fluoro - 2,4 - Dibromobenzene, which is in the field of our chemical research, has many aliases and trade names.
Its aliases, in terms of chemical nomenclature, or according to the atomic position and functional group characteristics. Above the benzene ring, the fluorine atom occupies 1 position, and the bromine atom occupies 2 and 4 positions, so there are also people who call it by its position relationship and functional group combination. Although the description is slightly different, it is referred to as this thing.
As for the trade name, when it is circulated in the market, merchants may give different names to highlight their characteristics and facilitate customer identification. However, whether it is an alias or a trade name, it all refers to this 1 - Fluoro - 2,4 - Dibromobenzene. This is the common situation of chemical substances in the use of names, and they have different names depending on the scene and purpose. However, the entity referred to is the only one. Those who study this thing should be clear about what the names refer to to to avoid confusion, so as to study their properties and make good use of their capabilities.
Safety & Operational Standards
1 - Fluoro - 2,4 - Dibromobenzene is an important chemical substance that is used in many fields. However, its properties are special, so strict guidelines are required in terms of safety and operating practices.
First of all, it is related to the safety of storage. This substance should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Because it has certain chemical activity, it may cause dangerous reactions if heated or exposed to open flames. Anti-corrosive materials must be used for storage to avoid chemical reactions with the container and cause leakage.
When operating, there are also many regulations. Operators must wear professional protective equipment, such as protective clothing, protective gloves and goggles. Due to the substance or cause damage to the skin, eyes, etc. The operation process needs to be carried out in the fume hood to ensure that the volatile gas can be discharged in time to prevent inhalation of the human body and endanger health.
In addition, the equipment used should also be carefully selected. The reaction vessel and experimental equipment suitable for the substance should be selected to avoid affecting the experimental results due to improper materials and even causing safety accidents. The experimental operation steps must strictly follow the established procedures and cannot be changed at will.
In terms of waste disposal, it must not be discarded at will. Waste containing 1 - Fluoro - 2,4 - Dibromobenzene should be disposed of according to specific procedures to prevent pollution to the environment.
Only by strictly following the above safety and operating practices can we ensure that during the use of 1-Fluoro-2,4-Dibromobenzene, personnel safety is guaranteed, and experimental or production activities are carried out smoothly, while also reducing the adverse impact on the environment.
Application Area
1 - Fluoro - 2,4 - Dibromobenzene is a special chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new specific drugs to deal with specific diseases and bring good news to patients. In the field of materials science, it can participate in the preparation of high-performance materials, improve the properties of materials, such as enhancing their stability and functionality, making materials suitable for special environments and high-end needs. Furthermore, in the study of organic synthetic chemistry, this compound also plays an important role, providing a powerful tool for chemists to explore new reaction paths and expand the boundaries of chemical knowledge. Its unique chemical structure endows it with diverse reactivity, allowing researchers to build complex and unique organic molecular structures, thus promoting the continuous development and progress of the field of chemistry.
Research & Development
A Japanese researcher, try to study 1 - Fluoro - 2,4 - Dibromobenzene. At first, explore its properties, test its quality, measure its solubility in various solvents, and observe its state of temperature change. Re-study the method of its synthesis, try various techniques, in order to seek high-efficiency and pure products. Using the method of catalysis, adjust the amount of its agent, when and when it should be, and the temperature, in order to obtain the best production.
During the research, there are many problems encountered. If impurities are produced at the right time, the product is impure. It is a detailed analysis of the process, observe the situation of each step, and choose the catalyst to control the environment, and the impurities are gradually reduced. In addition, the yield did not meet expectations, so the mechanism was studied and the order of operation was changed, and the yield rose.
After long-term research, the properties and systems of 1-Fluoro-2,4-Dibromobenzene have been tested. And with the results, think about the field of application. Hope this research can be a lesson for colleagues, and help this product be widely used in industry, medicine and other industries to promote development.
Toxicity Research
In recent years, I have been studying chemical substances, with particular emphasis on 1 - Fluoro - 2,4 - Dibromobenzene. Its properties are crucial to the investigation of toxicity.
After various experiments, I have carefully observed its reaction. In a specific environment, it comes into contact with other things, or produces strange changes. Looking at the structure of its molecules, fluorine and bromine atoms are listed in the benzene ring, and this structure may be the source of its poison.
Test with white mice, fed with something containing this agent. Not long after, the state of the white mice gradually changed, the vitality declined, and the diet also decreased. Test its physiological signs, and the organs seem to be disturbed by it. The process of its metabolism is re-analyzed, and this agent is difficult to dissolve in the body, gradually accumulating and harmful.
In summary, the toxicity of 1-Fluoro-2,4-Dibromobenzene should not be underestimated. Follow-up should be deeply studied, find a way to solve the harm, ensure the well-being of all beings, and protect the environment.
Future Prospects
In today's world, 1 - Fluoro - 2,4 - Dibromobenzene has great potential in the field of chemical research. The structure of this substance is unique, and fluorine and bromine atoms are cleverly intertwined on the benzene ring, which seems to have infinite possibilities.
In the future, it may shine in the road of pharmaceutical synthesis. Its special structure may accurately fit certain disease targets, paving the way for the creation of specific new drugs. The way of medicine is to seek precise and efficient drugs, and this substance may be a key help.
In the field of materials science, it also has potential. It may be able to participate in the construction of new functional materials, endowing materials with unique optical and electrical properties, and contributing to material innovation.
We researchers should immerse ourselves in our research, explore its mysteries, lead it on the right path, and develop its grand future, so as to live up to the potential hidden in this material.
Where to Buy 1-Fluoro-2,4-Dibromobenzene in China?
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Frequently Asked Questions

As a leading 1-Fluoro-2,4-Dibromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Fluoro-2,4-Dibromobenzene?
1-Fluoro-2,4-dibromobenzene is one of the organic compounds. Its main use is very important in the field of organic synthesis.
In the field of medicinal chemistry, it is often a key intermediate in the synthesis of various biologically active compounds. The unique electronic and spatial effects of fluorine and bromine atoms on the benzene ring can be used to ingeniously introduce specific functional groups through chemical reactions to create drug molecules with novel structures and specific activities. For example, through specific substitution reactions, coupling reactions, etc., complex drug frameworks can be constructed, paving the way for the development of new drugs.
In the field of materials science, it also has its uses. Due to its special chemical structure, it can participate in the preparation of materials with special properties. For example, the synthesis of organic semiconductor materials with specific optoelectronic properties can be used in organic Light Emitting Diode (OLED), organic solar cells and other devices. By precisely regulating its molecular structure, the electrical and optical properties of the material can be optimized, and the performance and efficiency of the device can be improved.
In addition, in pesticide chemistry, 1-fluoro-2,4-dibromobenzene is also an important raw material for the synthesis of high-efficiency and low-toxicity pesticides. After chemical modification, a series of pesticide varieties with high selectivity, strong killing power and environmental friendliness can be derived, contributing to agricultural pest control. Therefore, with its unique chemical structure, 1-fluoro-2,4-dibromobenzene has shown important application value in many fields such as medicine, materials, and pesticides, promoting the progress and development of related industries.
What are the physical properties of 1-Fluoro-2,4-Dibromobenzene?
1-Fluoro-2,4-dibromobenzene is one of the organic compounds. It has unique physical properties, which are described below.
First of all, its appearance, under normal temperature and pressure, 1-fluoro-2,4-dibromobenzene is often colorless to light yellow liquid, clear and with a certain fluidity. Looking at its color, the characterization of this light yellow is due to factors such as electron transitions between atoms in its molecular structure, giving it a unique external appearance.
Describe its boiling point for the second time. According to many experimental measurements, its boiling point is about a specific temperature range. The value of this boiling point is closely related to the intermolecular forces. The electronegativity of atoms such as fluorine and bromine in the molecule is relatively large, resulting in a strong dipole-dipole force between molecules. To make the molecule break free from the liquid phase and turn into the gas phase, it needs to supply the corresponding energy, so this boiling point value is presented.
Furthermore, on its melting point. The melting point of 1-fluoro-2,4-dibromobenzene is also one of its important physical properties. Under certain conditions, when the temperature drops to a certain value, the substance gradually changes from liquid to solid. The level of this melting point is related to the degree of regular arrangement of molecules and the force between molecules. The spatial arrangement of atoms in its molecular structure affects the strength of the interaction between molecules, and then determines the value of the melting point.
Repeat its solubility. This compound exhibits good solubility in organic solvents, such as common ether, dichloromethane, etc. Because its molecular structure has both a certain polar and non-polar part, it can be dissolved in organic solvent molecules through Van der Waals force, dipole-dipole interaction, etc. However, in water, its solubility is poor because of its weak force with water molecules and strong hydrogen bond between water molecules.
In addition, the density of 1-fluoro-2,4-dibromobenzene is also a key physical property. Its density is greater than that of water, and it can be clearly seen that it sinks to the bottom when it is co-placed with water in a container. This density characteristic is due to the type and quantity of atoms in the molecule and their relative atomic mass. The close arrangement and large mass of the atoms make the density of the substance relatively large.
The physical properties of 1-fluoro-2,4-dibromobenzene, such as appearance, boiling point, melting point, solubility and density, are determined by its molecular structure, and in many fields such as organic synthesis and chemical production, due to these unique physical properties, it has important application value and research significance.
What is the chemical synthesis method of 1-Fluoro-2,4-Dibromobenzene?
1-Fluoro-2,4-dibromobenzene is also an organic compound. The method of its synthesis has been described in many ancient books.
To make 1-fluoro-2,4-dibromobenzene, one of the common methods starts with benzene. First, the method of bromination is used to combine benzene and bromine under appropriate conditions, such as iron or iron tribromide as a catalyst, and in the state of heating, the two phases combine to obtain bromobenzene. At this time, one of the hydrogen atoms on the benzene ring is replaced by a bromine atom.
Then, p-bromobenzene is re-brominated. This step also requires a catalyst, and the conditions should be precisely controlled so that the bromine atom mainly replaces the bromobenzene o-and the hydrogen atom in the para-position to obtain 1,3-dibromobenzene. This is the case because the bromo group is an ortho-and para-locator.
Finally, the method of fluorination is used to make 1,3-dibromobenzene interact with fluorine-containing reagents. It is often possible to use potassium fluoride, etc., to replace a certain bromine atom in 1,3-dibromobenzene with a fluorine atom under suitable solvent and heating conditions, so that 1-fluoro-2,4-dibromobenzene is obtained.
However, in the process of synthesis, it is necessary to pay attention to the conditions of each step of the reaction, such as temperature, amount of catalyst, proportion of reactants, etc., which are all related to the purity and yield of the product. The operation of each step should be done carefully, so that the purpose of synthesis can be achieved and pure 1-fluoro-2,4-dibromobenzene can be obtained.
What are the precautions for storing and transporting 1-Fluoro-2,4-Dibromobenzene?
1-Fluoro-2,4-dibromobenzene is also an organic compound. When storing and transporting, all precautions should not be ignored.
First words storage. This compound should be placed in a cool and ventilated warehouse. The cover should be kept away from fire and heat sources because it is easy to decompose when heated and causes danger. The temperature of the warehouse should be strictly controlled and should not be too high. It should be stored separately from oxidants and alkalis, etc., and mixed storage should not be avoided. Due to its active chemical properties, it can mix with other substances or cause chemical reactions, which can cause safety accidents. At the same time, the warehouse needs to have suitable materials to contain leaks, in case of leaks, it can be properly handled in a timely manner.
As for transportation. Before transportation, it is necessary to ensure that the packaging is complete and the loading is safe. The packaging should be able to effectively prevent the leakage and volatilization of the compound. During transportation, it is necessary to ensure that the container does not leak, collapse, fall or damage. The transportation vehicle should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. Summer transportation should be carried out in the morning and evening to avoid high temperature periods, because high temperature may increase its danger. And during transportation, it should be protected from sun exposure, rain and high temperature. When road transportation, it should follow the prescribed route and do not stop in residential areas and densely populated areas. When rail transportation, it is also necessary to abide by relevant regulations to ensure safe transportation. In this way, the safety of personnel and the environment should be guaranteed during the storage and transportation of 1-fluoro-2,4-dibromobenzene.
What are the effects of 1-Fluoro-2,4-Dibromobenzene on the environment and human health?
1-Fluoro-2,4-dibromobenzene is also an organic compound. Its impact on the environment and human health is of considerable concern.
At the environmental end, this compound has a certain stability and is difficult to degrade naturally. If it is released into the soil, it may be adsorbed on soil particles, affecting the physical and chemical properties of the soil, hindering the absorption of nutrients and moisture by plant roots, and causing plant growth to be hindered. And may penetrate into groundwater through the soil, polluting groundwater resources and threatening the safety of surrounding water sources. If it escapes into water bodies, due to its hydrophobicity, it may be enriched in aquatic organisms, transmitted and amplified through the food chain, causing serious impact on aquatic ecosystems and disrupting ecological balance.
As for human health, 1-fluoro-2,4-dibromobenzene may be toxic. After inhalation, skin contact or ingestion into the human body, it may damage multiple systems of the human body. It may irritate the respiratory mucosa, cause cough, asthma and other discomfort, long-term exposure, or cause respiratory diseases. Contact with the skin, or cause skin allergies, redness, swelling, itching and other symptoms. If it enters the digestive system, or damages the gastrointestinal mucosa, it may cause nausea, vomiting, abdominal pain, etc. In particular, this compound may have potential carcinogenicity and teratogenicity, affect the reproductive and genetic health of the human body, and endanger future generations.
Therefore, in the production, use and disposal of 1-fluoro-2,4-dibromobenzene, care should be taken to follow strict safety regulations and environmental protection standards to reduce its harm to the environment and human health.