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1-Fluoro-2,3-Dinitrobenzene

1-Fluoro-2,3-Dinitrobenzene

Hongda Chemical

Specifications

HS Code

391393

Chemical Formula C6H3F(NO2)2
Molar Mass 186.09 g/mol
Appearance Yellow solid
Melting Point 43 - 46 °C
Boiling Point 265 - 266 °C
Density 1.57 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
Flash Point 129.4 °C
Vapor Pressure Low at room temperature
Odor Characteristic, pungent

As an accredited 1-Fluoro-2,3-Dinitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - fluoro - 2,3 - dinitrobenzene packaged in a sealed, chemical - resistant bottle.
Storage 1 - fluoro - 2,3 - dinitrobenzene should be stored in a cool, dry, well - ventilated area away from heat, flames, and ignition sources. Keep it in a tightly - sealed container, preferably in a corrosion - resistant material. Store it separately from incompatible substances like oxidizing agents, reducing agents, and bases to prevent chemical reactions. Regularly check storage conditions for integrity.
Shipping 1 - fluoro - 2,3 - dinitrobenzene is a hazardous chemical. Shipping requires proper packaging in accordance with regulations. It must be labeled clearly, and transported by carriers licensed for handling such substances to ensure safety.
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1-Fluoro-2,3-Dinitrobenzene 1-Fluoro-2,3-Dinitrobenzene
General Information
Historical Development
1 - Fluoro - 2,3 - Dinitrobenzene is also a chemical substance. At the outset, various sages studied the field of chemistry and wanted to explore the wonders of new substances. At the beginning, their characteristics and production methods were carefully studied.
In the past, everyone tried repeatedly in the laboratory to synthesize this substance with exquisite methods. At the beginning, it may be difficult, and the yield is not as satisfactory, but chemists are determined and fail again and again.
Over the years, the understanding of 1 - Fluoro - 2,3 - Dinitrobenzene has deepened. It has gradually become useful in organic synthesis and other fields, and is a key material for many reactions. With the in-depth research, the production method is improved, the yield is improved, and the application is also gradually widened. The efforts of chemists have made it famous and important to the academic and industry, adding a touch of brilliance to the long road of chemical development and becoming a part of the evolution of chemical history.
Product Overview
1 - Fluoro - 2,3 - Dinitrobenzene is an important intermediate in organic synthesis. It is a light yellow to yellow crystalline powder with specific physical and chemical properties. The melting point is about [X] ° C and the boiling point is [X] ° C. This compound has high chemical activity due to the presence of fluorine atoms and dinitro groups.
In the field of organic synthesis, 1 - Fluoro - 2,3 - Dinitrobenzene is often used as an electrophilic reagent and undergoes nucleophilic substitution reactions with many nucleophilic reagents. For example, it can react with amines to efficiently generate nitrogen-containing derivatives, which are widely used in drug synthesis, materials science and other fields. Its unique structure endows the product with special properties, providing the possibility for the development of new materials and drugs.
The preparation of 1 - Fluoro - 2,3 - Dinitrobenzene is usually made from specific benzene derivatives through a series of reactions such as nitrification and fluorination. However, the reaction conditions need to be precisely controlled to ensure the purity and yield of the product.
1 - Fluoro - 2,3 - Dinitrobenzene is of great significance in organic synthesis. With its unique structure and reactivity, it promotes the development of many fields.
Physical & Chemical Properties
1 - Fluoro - 2,3 - Dinitrobenzene is also a chemical substance. Its physical nature is low, the color is light, and the liquid is thick, with a special taste. The melting temperature is low, the temperature is below zero, and the boiling temperature is below 100 degrees. The density is large in water. It is insoluble in water, but it is soluble in many kinds of water.
Its chemical properties are high because it contains fluorine, nitro and other groups. The activity of fluorine atoms can cause its nuclear substitution and reaction. The presence of nitro groups reduces the density of benzene molecules, making them vulnerable to nuclear attack. In the field of synthesis, this compound is often used to introduce specific radicals, which are of great importance. It plays an important role in the synthesis of compounds, dyes, etc., and is indispensable for chemical research and engineering.
Technical Specifications & Labeling
1 - Fluoro - 2,3 - Dinitrobenzene is an important chemical product. Its process specifications and labeling (product parameters) are related to many key elements.
In terms of process specifications, the selection of raw materials needs to be carefully selected, and the proportion of each ingredient must be precisely controlled. For example, the purity of the reactants needs to reach a very high standard to ensure the smooth progress of the reaction. The reaction conditions are also extremely critical. The temperature and pressure need to be adjusted exactly. Usually, the reaction temperature should be maintained in a specific range, and the pressure also needs to meet the corresponding requirements, so that the ideal product quality and yield can be obtained.
On the label (product parameters), the appearance should show a specific color and shape, which is the preliminary basis for discrimination. The purity index is the most important, which needs to reach a specific percentage, and the impurity content should be strictly controlled at a very low level. In addition, the identification of relevant physical and chemical properties, such as melting point, boiling point and other parameters, are important references for identifying the product. Strict adherence to process specifications and precise identification (product parameters) can make 1 - Fluoro - 2,3 - Dinitrobenzene play its due role in various applications.
Preparation Method
The method of making 1-Fluoro-2,3-Dinitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism.
First take benzene as the base, heat it with mixed acid of nitrate and sulfur, and carry out the method of nitrification to obtain m-dinitrobenzene. This step requires precise temperature control and does not cause side reactions.
Next, anhydrous potassium fluoride, in a specific solvent, is azeotropic with m-dinitrobenzene to promote fluorination. During the reaction, when the temperature and pressure changes, and the catalyst is selected to increase the reaction rate, such as quaternary ammonium salts, which can promote ion exchange and fluorine atom substitution.
After the reaction is completed, it is refined by distillation, extraction and recrystallization. The low-boiling matter is first distilled to remove the impurity, and then the pure product is recrystallized. In this way, following this series of steps, 1-Fluoro-2,3-Dinitrobenzene can be obtained.
Chemical Reactions & Modifications
1 - Fluoro - 2,3 - Dinitrobenzene is an important chemical synthesis. Its chemical reaction is delicate and changeable, and it is related to the principle of many chemical transformations.
In the past, the reaction was often limited by specific conditions, and there was room for improvement in yield and purity. However, after repeated research, we found an optimization method. In the past, the reaction was often used in ordinary solvents, but now a special mixture of solvents is used, and the reaction environment is more suitable, and the rate can be improved.
Furthermore, the regulation of temperature and catalyst is also key. Precise temperature control and the selection of high-efficiency new catalysts greatly improved the selectivity of the reaction. As a result, the purity of the product increased significantly, and side reactions were suppressed.
After this improvement, the chemical properties of 1-Fluoro-2,3-Dinitrobenzene are better, paving the way for subsequent applications, and have broad prospects in the fields of chemical industry and materials.
Synonyms & Product Names
1 - Fluoro - 2,3 - Dinitrobenzene, this substance is a treasure of chemistry. Its alias and trade name are like stars, each with its own wonders.
Guanfu alias, or according to its structural characteristics, highlights the unique structure of the molecule; or according to its properties, it has extraordinary performance. And the trade name contains the ingenuity of merchants and wants to attract everyone's attention.
This compound plays an extraordinary role in the field of chemical research. Its unique structure endows many special reactions, and it is often the key to the creation of new substances in the process of organic synthesis. With their aliases and trade names, researchers can easily shuttle between academic exchanges and experimental operations, accurately locate, and deeply explore their mysteries, hoping to contribute to the development of chemistry, help the wheels of science and technology roll forward, and expand into new chapters in the unknown.
Safety & Operational Standards
1 - Fluoro - 2,3 - Dinitrobenzene is also a chemical substance. In the room, its safe operation is very important and should not be ignored.
This compound has a certain degree of danger. Its properties are not active, and in case of open flame, high temperature or oxidation, it may cause combustion and explosion. Therefore, there is no fire source or source, and it cannot be oxidized and mixed.
When operating, the operator must take appropriate precautions. Wear anti-eye protection to avoid possible damage to the eyes; take precautions to prevent skin contact; wear anti-gloves to ensure hand safety.
Take it out, it is appropriate to do so, and do not rush to avoid accidents. Remove this object, use the appropriate equipment, and keep it in good condition. If it is accidentally dropped, do not panic, and quickly remove the source of fire and gas to avoid friction and collision. That is, cover it with an appropriate adsorption material, collect it carefully, and handle it properly according to the phase.
Once the skin is connected, immediately wash the dyed clothes with a large amount of water for at least 15 minutes, and then wash it immediately. If it enters the eyes, lift the eyes immediately, wash the bottom with a large amount of water or physiological water, and ask for help quickly.
In the research and operation of 1 - Fluoro - 2,3 - Dinitrobenzene, safety must be the first, and the operation must be observed. Only then can it be avoided and prevented.
Application Area
1 - Fluoro - 2,3 - Dinitrobenzene is an important raw material for organic synthesis. In the field of medicine, it can be used to prepare specific targeted drugs. With its unique chemical structure, it can precisely act on diseased cells and assist in disease treatment. In the field of materials science, it can participate in the synthesis of new functional materials, endowing materials with special electrical and optical properties.
Looking back at the past, chemical masters have studied the properties and reactions of substances to obtain this compound. Its reaction mechanism is exquisite, and through multiple steps of reaction, a unique structure is ingeniously constructed. Today, with the development of science and technology, the application prospects of this compound are broader. However, when applying, its safety and environmental impact need to be carefully considered.
Scholars should uphold the spirit of exploration, conduct in-depth research on its application potential, optimize the synthesis path, and make it better serve humanity. They should shine in the fields of medical excellence and material innovation, and seek well-being for the world. They should live up to the mission of scientific exploration.
Research & Development
1 - Fluoro - 2,3 - Dinitrobenzene is an important chemical substance. I investigated its properties in detail during my research. This substance has unique properties and its reaction mechanism is interesting.
After repeated experimental investigations, I found that it can exhibit extraordinary reactivity under specific conditions. I am committed to analyzing the relationship between its structure and properties, hoping to gain a deeper understanding of its inner mysteries.
During the research process, many problems lay ahead, but I was not discouraged. By adjusting the experimental parameters and changing the reaction conditions, I finally achieved a key breakthrough.
Looking to the future, 1 - Fluoro - 2,3 - Dinitrobenzene may have broad application prospects in materials science and other fields. I will continue to study it with the hope of promoting its further development and contributing to the progress of the chemical field.
Toxicity Research
Toxicity Study of 1 - Fluoro - 2,3 - Dinitrobenzene
Husband 1 - Fluoro - 2,3 - Dinitrobenzene is also a chemical substance. Our chemical product researchers are concerned about its toxicity, so this is an investigation.
The toxicity of this substance is related to a lot. The cells of its or harmful organisms are dry and the process of replacement., as the image of this substance, apply this substance to its physiology. It may invade the liver, and the order of its function.
And test the shadow of its environment. If it is outside, it is afraid of the realm of water and soil, endangering the balance of life. Its chemical activity, or the reaction of other things, produce more toxic things.
is to study the toxicity of 1 - Fluoro - 2,3 - Dinitrobenzene, with caution. To study its harm, in order to prevent the strategy, to ensure the safety of people, the beauty of the environment.
Future Prospects
Wuguanfu 1 - Fluoro - 2,3 - Dinitrobenzene This product has unique properties and a wide range of uses. In today's world, although it has been explored, there are still endless possibilities for future development.
Or it can be used in fine chemicals to make products more delicate and of extraordinary quality. In the process of pharmaceutical research and development, it is also expected to shine, finding new paths for the treatment of diseases. In material science, it may be able to generate exotic materials to meet the needs of future technology.
With the increasing technology, the deeper the research, the more hidden capabilities it will be able to tap. In the future, 1 - Fluoro - 2,3 - Dinitrobenzene will surely come out of the dust like a pearl, shining brightly in various fields, opening up new opportunities for the well-being of mankind, achieving extraordinary things, and developing endless prospects.
Where to Buy 1-Fluoro-2,3-Dinitrobenzene in China?
As a trusted 1-Fluoro-2,3-Dinitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Fluoro-2,3-Dinitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Fluoro-2,3-Dinitrobenzene?
1-Fluoro-2,3-dinitrobenzene is also an organic compound. Its main use is quite wide.
First, in the field of organic synthesis, it is often used as a key intermediate. In its molecular structure, the presence of fluorine atoms and dinitro groups endows it with unique reactivity. Through nucleophilic substitution, fluorine atoms can be easily replaced by many nucleophilic reagents, such as hydroxyl groups, amino groups, etc. In this way, various organic molecules containing specific functional groups can be constructed. In the field of medicinal chemistry, it is helpful to create drug molecules with novel structures, paving the way for finding effective therapeutic agents.
Second, it also has a potential in materials science. Due to its special chemical structure, it can participate in the synthesis of polymer materials. Copolymerization with suitable monomers can improve the properties of polymer materials, such as thermal stability, mechanical properties, etc. Or it can be used as a functional additive, introduced into the material system, endowing the material with special optoelectronic properties, and may have potential applications in the field of electronic materials.
Third, when studying the chemical reaction mechanism, 1-fluoro-2,3-dinitrobenzene is often an ideal model compound. By exploring the various reactions in which it participates, researchers can gain insight into the fine processes of nucleophilic substitution, aromatic electrophilic substitution, etc., which adds to the improvement of organic chemistry theory and helps chemists to more accurately grasp the reaction law, optimize the reaction conditions, and improve the efficiency and selectivity of organic synthesis.
What are the physical properties of 1-Fluoro-2,3-Dinitrobenzene?
1-Fluoro-2,3-dinitrobenzene is also an organic compound. It has all kinds of physical properties, let me come to you one by one.
First of all, its appearance, under normal conditions, is mostly light yellow crystalline, and it looks quite crystal clear, just like fine glass, emitting a unique luster, which attracts attention.
As for the melting point, it is about 57 ° C to 59 ° C. This temperature range is like a boundary. When the ambient temperature rises, this substance gradually melts from a solid state to a liquid state, and the shape change is amazing.
The boiling point is also one of its important physical properties, reaching about 296 ° C. At this high temperature, 1-fluoro-2,3-dinitrobenzene in the liquid state will turn into a gaseous state and rise in space.
In terms of solubility, it is quite compatible with organic solvents such as ethanol and ether, and can be evenly dispersed. It is like a fish entering water and fusing into one. However, in water, it is difficult to dissolve. The two seem to be distinct, and each keeps its own boundaries.
The density is also a consideration. Its density is greater than that of water, so if it encounters water, it will sink to the bottom of the water, just like a heavy object sinks, following the laws of nature.
The physical properties of 1-fluoro-2,3-dinitrobenzene are generally like this, which are all inherent characteristics. In the field of chemistry, it is of great significance to help us understand and study this substance.
What are the chemical properties of 1-Fluoro-2,3-Dinitrobenzene?
1 - Fluoro - 2,3 - Dinitrobenzene is one of the organic compounds. It is active and has attracted much attention in the field of organic synthesis.
In this substance, the fluorine atom is connected to the dinitrobenzene ring. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring, making its electrophilic substitution activity different from that of the ordinary benzene ring. Although fluorine atoms are also electron-withdrawing groups, they can participate in nucleophilic substitution reactions, which is one of the important characteristics of this compound.
In the nucleophilic substitution reaction, due to the strong electron-withdrawing effect of nitro, the density of the carbon check point electron cloud attached to the fluorine atom is further reduced, and it is more susceptible to the attack of nucleophilic reagents, resulting in nucleophilic Common nucleophilic reagents such as alcohols and amines can react with them to form corresponding substitution products. This property makes it widely used in drug synthesis, material preparation and many other fields.
Furthermore, it has certain chemical stability, and it can also undergo chemical reactions when heated or in contact with specific chemical reagents. The nitro part may participate in the reduction reaction and be converted into other functional groups such as amino groups, further expanding its diversity in organic synthesis pathways. However, due to its nitro content, it has certain oxidation and potential danger. Strict safety procedures must be followed during operation and storage to prevent accidents.
In conclusion, 1-Fluoro-2,3-Dinitrobenzene has shown important research and application value in the field of organic chemistry due to its unique chemical properties, but its operation and use need to be treated with caution.
What are the synthesis methods of 1-Fluoro-2,3-Dinitrobenzene?
The synthesis method of 1-fluoro-2,3-dinitrobenzene has been known since ancient times. In the past, craftsmen have learned from the techniques of alchemy and pharmacy and gold stone smelting, but there was no accurate description at that time, it was only an oral experience.
Since modern times, science has become more and more enlightened, and the synthesis method has gradually become more systematic. First, take benzene as the base, first nitrate the benzene. Choose the appropriate nitrifying reagent, such as the mixed acid of concentrated nitric acid and concentrated sulfuric acid, at the right temperature and reaction time, you can get nitrobenzene. This step requires careful observation of the temperature. If it is too high, side reactions will occur, and if it is too low, the reaction will be slow. Then, the p-nitrobenzene is nitrified again to introduce a second nitro group to obtain 1,3-dinitrobenzene. This process also requires fine regulation of the reaction conditions to enable precise localization of nitro groups.
As for the introduction of fluorine atoms, nucleophilic substitution is often used. Take 1,3-dinitrobenzene, and fluorine-containing reagents, such as potassium fluoride, in specific solvents, such as dimethyl sulfoxide (DMSO), with the help of high temperature and phase transfer catalysts, fluorine ions nucleophilic attack on the benzene ring appropriate check point, substitution of the corresponding group, and finally 1-fluoro-2,3-dinitrobenzene. In this synthesis, each step needs to strictly abide by the procedures and precisely control the reaction conditions in order to improve the yield and obtain a pure product.
What are the precautions for 1-Fluoro-2,3-Dinitrobenzene during use?
1-Fluoro-2,3-dinitrobenzene is a chemical substance. When using it, many things must be observed.
First, this substance is toxic and irritating, and it can hurt the skin, eyes, absorb it, or damage breathing. Therefore, when using it, protective equipment is essential. Wear protective clothing, gloves, goggles, and handle it in a well-ventilated place, or use a fume hood to prevent harmful gases from entering the body.
Second, it is flammable, and in case of open flames and hot topics, it can cause the risk of combustion and explosion. When storing, it should be kept away from fire and heat sources, separated from oxidants and flammable substances, and properly stored to prevent accidents.
Third, when using this substance for reaction, the control of reaction conditions is crucial. Temperature, pH and other factors can affect the process and results of the reaction. It is necessary to precisely adjust the conditions according to the requirements of the reaction to achieve the expected effect.
Fourth, during operation, it is necessary to be careful. Steps such as measuring and transferring should be done slowly to prevent it from overflowing and spilling. If it is accidentally spilled, clean it up according to relevant methods to prevent it from spreading and causing greater harm.
Fifth, after the experiment is completed, the remaining items should not be discarded at will. It should be properly disposed of in accordance with regulations to avoid polluting the environment. The utensils used should also be washed for next use.
In short, when using 1-fluoro-2,3-dinitrobenzene, protection, storage, operation, handling and other things must be strictly followed to ensure safety and promote the success of the experiment.