1-Fluoro-2,3-Dimethyl-4-Nitrobenzene

Hongda Chemical

Specifications

HS Code	732646
Chemical Formula	C8H8FNO2
Molar Mass	169.153 g/mol
Appearance	Solid (likely)
Physical State At Room Temperature	Solid
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, toluene
Vapor Pressure	Low (due to being a solid at room temperature)
Stability	Stable under normal conditions but can react under certain chemical environments

As an accredited 1-Fluoro-2,3-Dimethyl-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 1 - fluoro - 2,3 - dimethyl - 4 - nitrobenzene packaged in a sealed chemical - grade bottle.
Storage	1 - fluoro - 2,3 - dimethyl - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. It should be stored in a tightly closed container, preferably made of corrosion - resistant materials. Keep it separate from oxidizing agents, reducing agents, and other reactive chemicals to prevent potential reactions.
Shipping	1 - fluoro - 2,3 - dimethyl - 4 - nitrobenzene is shipped in accordance with strict chemical transport regulations. It's carefully packaged in suitable containers to prevent leakage during transit, ensuring safety in handling and transportation.

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General Information

Historical Development

1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene is an important chemical product. Tracing its historical development, the field of organic synthesis has been continuously explored by chemical experts in the past. At first, the relevant synthesis methods were still crude and the yield was not satisfactory. However, over time, scholars persevered and carefully adjusted the reaction conditions, improved the catalyst, and optimized the reaction path. After many hardships, the synthesis efficiency and purity of this product were gradually improved. From its humble beginnings to today's relatively mature preparation process, this process has witnessed the unremitting efforts and wisdom of the chemical industry, which has made 1-Fluoro-2,3-Dimethyl-4-Nitrobenzene widely used in many fields such as medicine and materials, and promoted the vigorous development of related industries.

Product Overview

1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene is an organic compound. Its shape may be crystalline, and its color may be light yellow. This compound has unique chemical properties. The coexistence of fluorine atoms, methyl groups and nitro groups makes its reactivity different from that of ordinary benzene series.
In terms of its preparation, it often requires several steps of organic synthesis. Through a specific reaction path, each group is introduced into the benzene ring in precise steps. The introduction of fluorine atoms requires the selection of suitable fluorination reagents and reaction conditions to ensure its selectivity and yield. The addition of methyl and nitro groups also needs to regulate the temperature, time and ratio of reactants according to the principles of organic chemistry.
1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene has great application potential in the field of organic synthesis. It can be used as an intermediate to prepare materials with special functions, or as a key structural unit in pharmaceutical chemistry, providing an opportunity for the development of new drugs. Its unique structure gives it a variety of reaction possibilities, allowing chemists to explore new reaction pathways and synthesis strategies to expand the boundaries of organic chemistry.

Physical & Chemical Properties

1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene is an organic compound. Its physical properties are either solid at room temperature or crystalline, with a certain color. Due to the benzene ring structure, the melting boiling point may be relatively high, and it has a specific vapor pressure.
In terms of chemical properties, fluorine atoms have high electronegativity, resulting in a change in the electron cloud density distribution of the benzene ring, which makes this compound exhibit unique activity in electrophilic substitution reactions. Methyl is the power supply group, which can increase the electron cloud density of the benzene ring, while nitro is a strong electron-absorbing group, which greatly reduces the electron cloud density of the benzene ring. This electronic effect interacts, resulting in complex and unique reactivity in many chemical reactions. It may participate in various reactions such as nucleophilic substitution and reduction, and has important application value in the field of organic synthesis.

Technical Specifications & Labeling

1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene is an important chemical product. Its technical specifications and labeling (product parameters) are related to the quality and application of this product. When looking at this substance, it is necessary to clarify its purity, which is a key indicator. If the purity is high, it can get better results in many reactions. Its appearance also needs to be precisely defined, and the color and shape cannot be ignored. In terms of identification, the name must be accurate, and the writing of 1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene should be standardized. In the product parameters, data such as molecular weight, melting point, boiling point, etc. can provide users with accurate guidance during storage and use, ensuring that the operation is carried out according to its characteristics and achieving the purpose of safety and efficiency.

Preparation Method

To prepare 1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene, its raw materials and production process, reaction steps, and catalytic mechanism are the key.
First take an appropriate amount of 2,3 - dimethylnitrobenzene as the starting material. In a specific reactor, anhydrous potassium fluoride is used as the fluorine source, and an appropriate amount of phase transfer catalyst is added. It is heated to a suitable temperature and maintained for a certain period of time. This step is the key to the fluorination reaction. During this period, the phase transfer catalyst can effectively promote the transfer of fluoride ions and improve the reaction efficiency.
When the reaction is sufficient, after cooling, extraction, distillation and other post-processing steps, impurities are removed, and crude products can be obtained. After recrystallization, high purity 1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene products can be obtained. The whole process requires precise control of the reaction conditions to ensure that each step is carried out in an orderly manner to obtain the ideal product.

Chemical Reactions & Modifications

The chemical reaction of 1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene should be related to chemical properties, which is the important task of chemical researchers. The chemical reaction of the chemical reaction is caused by the contact of things, such as the symmetry of yin and yang, and the transformation of new substances. The chemical reaction of this compound may involve nucleophilic substitution, the position of halogen and fluorine, or be induced by nitro and methyl groups, which changes its activity, causing nucleophiles to tend to it.
As for chemical properties, nitro groups have strong oxidizing properties, and the electronegativity of fluorine increases their activity. Although methyl groups are the power supply groups, the distribution of the overall electron cloud also has subtle tones. To improve its chemical response and clarify its chemical properties, it is necessary to study the reaction conditions, such as temperature, pressure, and catalysts, in order to precisely control, so that the chemical response is smooth and the product is pure. And the research results can open up new paths, and may be of great use in the fields of materials and medicine. It is our responsibility not to slack off.

Synonyms & Product Names

1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene, this substance is very important in the field of my chemical research.
The synonymous name, or fluorodimethylnitrobenzene, is simple, but it also accurately reflects its chemical composition. As for the name of the product, it should be in accordance with the general rules of the industry, or have a special name to distinguish and identify.
Gu Yun: "If the name is not correct, it will not go well." In chemical substances, the name is indeed crucial. The name of 1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene is based on the chemical nomenclature, which is precise and clear, so that our researchers can communicate without hindrance. And synonymous names can help communicate in different contexts. Trade names are useful in market circulation and product promotion.
As chemical industry professionals, we must carefully observe their names, know their synonyms and commodity names, so that we can study and apply them without confusion, move forward smoothly, and explore the wonders of chemistry.

Safety & Operational Standards

1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene is an important chemical compound. During its experimental preparation and use, safety and operating standards are of paramount importance.
Safety is the first word. This compound contains fluorine, nitro and other groups, which are toxic and potentially dangerous. When storing, store in a cool, dry and well-ventilated place, away from fire sources and oxidants to prevent serious accidents such as explosions. When taking it, the experimenter must wear protective clothing, goggles and gloves to avoid skin contact and inhalation of its volatile gases.
Next talk about operating standards. During synthesis, the reaction conditions need to be precisely controlled. Temperature, pressure, and the proportion of reactants are all key factors. For example, if the reaction temperature is too high, or side reactions occur, reducing the purity and yield of the product; if the temperature is too low, the reaction rate will be slow and take a long time. Furthermore, the stirring rate cannot be ignored. Moderate stirring can promote the full mixing of the reactants and speed up the reaction process. In the post-treatment stage, the separation and purification methods need to be carefully selected according to their physical and chemical properties. In view of its solubility characteristics, extraction, recrystallization and other means can be used to obtain high-purity products.
During operation, the cleaning and calibration of the instrument are also important. Unclean instruments or the introduction of impurities affect the experimental results; uncalibrated instruments, the data may be biased, resulting in increased experimental errors.
In conclusion, the research and application of 1-Fluoro-2,3-Dimethyl-4-Nitrobenzene must strictly follow safety and operating standards to ensure smooth experiments, personnel safety, and reliable results.

Application Area

1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene is a special chemical substance. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize drug molecules with specific pharmacological activities, which is of great significance for the treatment and research of diseases. In the field of materials science, its unique chemical structure may endow novel properties of materials, such as improving the stability and conductivity of materials, providing the possibility for the development of new materials.
Furthermore, in the field of organic synthetic chemistry, with its fluorine-containing, methyl and nitro structures, it can participate in a variety of chemical reactions, providing an effective path for the construction of complex organic molecules and promoting the development of organic synthetic chemistry. The application of this substance continues to expand, and it may emerge in more fields in the future, providing new opportunities for related scientific research and industrial production.

Research & Development

In recent years, I have a special preference for chemical substances, 1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene. This substance has unique properties and a wide range of uses, so I have studied it carefully.
The first time I dealt with this substance, looking at its structure, fluorine, methyl, nitro and benzene ring, the structure is exquisite and must have unique properties. Then I consulted the ancient books to explore the traces of its past research. Many ancestors have observed it, but there are still unfinished areas. My heart is eager for it, and I want to be exhausted.
So I set up various experiments to investigate the chemical properties and physical properties of this substance. Observe its solubility in different solvents, observe its changes when heated and exposed to light. The reaction mechanism is also studied, hoping to open up new ways and increase its use.
After months of research, some gains have been made. Knowing that it can be used in a specific reaction, high-purity products can be obtained, which are expected to be used in the production of new medicines. Although the road ahead is long, I firmly believe that unremitting research will enable 1-Fluoro-2,3-Dimethyl-4-Nitrobenzene to have a wider development and add new color to the field of chemistry.

Toxicity Research

1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene is a chemical substance, and we need to be careful about its toxicity research.
Looking at this compound, fluorine, nitro and other groups in its structure may have special properties. Although fluorine has a small atomic weight, it has strong electronegativity, which can often affect the polarity and chemical reactivity of molecules. Nitro is a strong electron-absorbing group, which has a significant impact on the distribution of electron clouds in compounds. The coexistence of the two may cause special reactions in organisms.
It has been observed through various experiments that it may damage the cells of organisms. In cell culture experiments, an appropriate amount of this compound can cause cell morphology changes and metabolic dysfunction. Animals were also used as experimental subjects to observe their reactions after ingestion or exposure to this substance, which may affect the normal functions of the nervous system and digestive system. From this point of view, the toxicity study of 1-Fluoro-2,3-Dimethyl-4-Nitrobenzene is really important, which is related to the safety of the environment and biology.

Future Prospects

I am committed to the research of 1 - Fluoro - 2,3 - Dimethyl - 4 - Nitrobenzene. Although it has been achieved today, there are still many things to be seen in the future.
Looking at this chemical, it has great potential in the field of organic synthesis. In the future, it may be extended to the preparation of more complex compounds to meet the needs of medicine, materials and other industries. And with the advancement of science and technology, the synthesis process is expected to be further optimized, the yield will be improved, and the cost will be reduced.
Furthermore, the study of its properties can also be more in-depth. Exploring its stability and reactivity in different environments may lead to new application directions. The future journey requires unremitting research, so that this chemical can bring innovation to many fields, in order to achieve unprecedented levels, live up to the original intention of our scientific research, and hope to benefit future generations and open up endless possibilities.

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Frequently Asked Questions

As a leading 1-Fluoro-2,3-Dimethyl-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of 1-Fluoro-2, 3-Dimethyl-4-Nitrobenzene?

1-Fluoro-2,3-dimethyl-4-nitrobenzene is also an organic compound. Its main uses are quite extensive, and it is often an important intermediate in the field of organic synthesis.
The cap has special chemical activity and reaction characteristics due to its unique structure, the presence of fluorine atoms, methyl groups and nitro groups. In the fine chemical industry, it can be used to create various materials with special properties. For example, using this as a starting material, through a series of chemical reactions, functional materials with specific optical and electrical properties can be prepared, which may have extraordinary applications in the field of optoelectronics.
Furthermore, it also has important value in pharmaceutical chemistry. By modifying and modifying its structure, or synthesizing compounds with potential biological activities, it is expected to be developed into new drugs. The functional groups carried by this compound can participate in a variety of reactions, providing the possibility to construct complex drug molecular structures and assisting the process of new drug development.
In the field of pesticide chemistry, based on 1-fluoro-2,3-dimethyl-4-nitrobenzene, efficient and targeted pesticide products can be created. Its special structure may enable it to exhibit good control effects against specific pests or pathogens, contributing to the control of pests and diseases in agricultural production.
In conclusion, 1-fluoro-2,3-dimethyl-4-nitrobenzene is an indispensable and important substance in many fields such as organic synthesis, medicine, and pesticides, and plays a significant role in promoting the development of related industries.

1-Fluoro-2, what are the physical properties of 3-Dimethyl-4-Nitrobenzene

1-Fluoro-2,3-dimethyl-4-nitrobenzene is one of the organic compounds. Its physical properties are worth a detailed investigation.
First of all, its phase state and color are mostly solid at room temperature, and the color is light yellow. Because of the nitro group in its molecular structure, the nitro group has electron absorption, which affects the absorption of light by the molecule and causes it to develop color.
times and melting point. The melting point of this material is moderate, and the intermolecular force is determined. Its molecules contain fluorine, methyl, nitro and other groups. The interaction between the groups, such as van der Waals force, dipole-dipole interaction, etc., requires specific energy to arrange the molecules in an orderly manner, so there is a corresponding melting point.
Let's talk about the boiling point again. The boiling point is related to the strength of the intermolecular force and the relative molecular weight. The relative molecular weight of 1-fluoro-2,3-dimethyl-4-nitrobenzene has a certain value, and the intermolecular force is not extremely weak, resulting in a very low boiling point. Moderate heat is required to make the molecule break free from the liquid phase and turn into the gas phase.
In terms of solubility, because it is an organic compound, it has a certain hydrophobicity and has a relatively small solubility in water. However, organic solvents, such as ethanol, ether, etc., have relatively high solubility due to the principle of similar miscibility. This is because organic solvents are similar to the molecular structure of the compound, and the acting forces can cooperate with each other, which is conducive to its dissolution.
Volatility is also an important physical property. Because the intermolecular force is not extremely strong, it has a certain volatility. However, compared with small molecule volatile organic compounds, its volatility is slightly weaker, because the relative molecular weight and the intermolecular force are restricted together.
In addition, density is also a consideration. Its density is slightly larger than that of water, which is closely related to the type, number and arrangement of atoms in the molecule. The molecules contain atoms with relatively large atomic masses such as fluorine and nitrogen, and the structure is closely arranged, so that their unit volume mass is greater than that of water.

Is 1-Fluoro-2, 3-Dimethyl-4-Nitrobenzene chemically stable?

The stability of the chemical properties of 1-fluoro-2,3-dimethyl-4-nitrobenzene depends on many factors. This substance has functional groups such as fluorine atom, methyl group and nitro group. Although fluorine atom is small, it has strong electronegativity, which can affect the density distribution of benzene ring electron cloud. Methyl group is the power supply, which can increase the density of benzene ring electron cloud and enhance its electron cloud richness, but also change the symmetry of benzene ring electron cloud. Nitro is a strong electron-absorbing group, which greatly reduces the density of benzene ring electron cloud and distorts the distribution of benzene ring electron cloud.
From the perspective of reactivity, nitro group significantly reduces the density of the electron cloud in the ortho and para-site of the benzene ring, and it is difficult to cause electrophilic substitution reactions to occur at this location; while methyl group increases the density of the electron cloud in the ortho and para-site relatively, and electrophilic substitution reactions may occur more easily at these locations. However, due to the strong electron-absorbing effect of nitro groups, in general, the electrophilic substitution activity of this compound is lower than that of benzene.
In terms of thermal stability, due to the different bonding modes and bond energies of each atom in the molecule, the thermal stability of each functional group is affected by the interaction of each functional group. The size of each bond energy and the interaction determine the difficulty of chemical bond breaking when the compound is heated. However, without specific experimental data or theoretical calculations, it is difficult
In summary, the chemical stability of 1-fluoro-2,3-dimethyl-4-nitrobenzene requires comprehensive consideration of reactivity, thermal stability, and other aspects. It is difficult to determine its absolute stability or instability simply. It varies depending on the specific environment and conditions.

What are the synthesis methods of 1-Fluoro-2, 3-Dimethyl-4-Nitrobenzene

The synthesis method of 1-fluoro-2,3-dimethyl-4-nitrobenzene has been known for a long time. This is a detailed description for you.
First, it can be started from aromatic hydrocarbons. Using xylene as raw material, first go through the nitration method. Put xylene in a suitable reaction vessel, use the mixed acid of concentrated nitric acid and concentrated sulfuric acid as nitrifying reagent, and control the temperature within an appropriate range. The upper hydrogen atom of xylene can be replaced by nitro to obtain 2,3-dimethyl nitrobenzene. In this step, pay attention to the ratio of mixed acid, reaction temperature and time to prevent excessive nitrification or formation of isomers.
Next step, halogenate 2,3-dimethyl nitrobenzene. A suitable halogenated reagent can be selected. For example, in the presence of a specific catalyst, fluoride is reacted with it to introduce fluorine atoms at a specific position on the benzene ring, and finally 1-fluoro-2,3-dimethyl-4-nitrobenzene is obtained. The selection and dosage of catalysts and the regulation of reaction conditions in this process are crucial, and the yield and purity of the product are related.
Second, other compounds containing benzene rings can also be used as starting materials. If a benzene derivative with a suitable substituent is found, it can be synthesized through a series of functional group transformations, such as the introduction of nitro groups first and then fluorine atoms, or vice versa, through multi-step reactions. However, this path often has many steps, and each step of the reaction needs to be carefully planned to ensure the smooth progress of each step of the reaction, and the control of the reaction conditions is more stringent.
During the synthesis process, it is necessary to operate carefully, pay attention to the details of each step of the reaction, and weigh the advantages and disadvantages of each method to effectively obtain this compound.

1-Fluoro-2, 3-Dimethyl-4-Nitrobenzene What are the precautions in storage and transportation?

1-Fluoro-2,3-dimethyl-4-nitrobenzene is also an organic compound. When storing and transporting, many matters need to be paid careful attention.
Bear the brunt, when storing, it should be placed in a cool and well-ventilated place. This compound is prone to danger when heated, and a cool environment can reduce its reactivity and reduce safety hazards. Well ventilated can prevent it from accumulating in the air, avoiding the risk of explosion or poisoning.
Furthermore, it must be kept away from fire and heat sources. Because of its flammability and explosiveness, in case of open flames and hot topics, it will explode instantly, endangering the surrounding area.
Storage should also be separated from oxidizing agents, reducing agents, alkalis, etc., and must not be mixed. This compound and their substances are prone to violent reactions, and disasters will occur.
Packaging must be tight. Make sure it does not leak or evaporate, and maintain stability. If the packaging is damaged, the substance will escape, which will not only cause environmental pollution, but also increase safety risks.
During transportation, do not slack off. Transportation vehicles must be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. During driving, drivers must pay close attention to prevent package damage and cargo leakage.
When loading and unloading, the operation should be light, and it is strictly forbidden to drop, touch, and hit. Due to its lively nature, rough operation can easily trigger dangerous reactions.
In short, the storage and transportation of 1-fluoro-2,3-dimethyl-4-nitrobenzene requires strict operation. Any omission can lead to disaster and cannot be ignored.