1-Ethyl-4-Fluorobenzene

Hongda Chemical

Specifications

HS Code	178119
Chemical Formula	C8H9F
Molar Mass	124.155 g/mol
Appearance	Colorless liquid
Odor	Aromatic odor
Density	0.97 g/cm³
Boiling Point	146 - 147 °C
Melting Point	Unknown
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in many organic solvents
Flash Point	34 °C
Vapor Pressure	Unknown
Logp	Unknown
Refractive Index	1.485 - 1.487

As an accredited 1-Ethyl-4-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	1 - ethyl - 4 - fluorobenzene packaged in 5 - liter containers.
Storage	1 - ethyl - 4 - fluorobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. It should be placed in a tightly - sealed container to prevent leakage and vapor release. Store it separately from oxidizing agents, acids, and bases. Ensure the storage area has proper spill - containment measures to handle any potential leaks safely.
Shipping	1 - ethyl - 4 - fluorobenzene is shipped in accordance with strict chemical regulations. It's typically packed in specialized containers to prevent leakage. Shipment may involve proper labeling, handling by trained personnel, and compliance with transportation safety standards for hazardous chemicals.

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General Information

Historical Development

1-Ethyl-4-fluorobenzene, the rise of this substance began with the prosperity of modern chemistry. At that time, all the sages studied the physical properties and studied the principles of chemical combination. Chemists began to prepare methods by gaining insight into the wonders of molecular structure through numerous experiments. At the beginning, the preparation was difficult, and the yield was very small, which was only a wonder in the laboratory.
However, science and technology have advanced day by day, and the preparation process has changed. Craftsmen improved the process and optimized the conditions, resulting in a gradual increase in the yield and quality. Since then, 1-ethyl-4-fluorobenzene has gradually entered the road of industrial practicality from laboratory microorganisms, and has emerged in various fields such as materials and medicine. It is used by the world and benefits the population. Its development process is really one of the evidence of chemical progress.

Product Overview

1 - Ethyl - 4 - Fluorobenzene is an organic compound. What is its shape? In terms of appearance, colorless and clear liquids also have special aromatic gases. What are their properties? Flammable, can cause combustion in case of open flames and hot topics.
This compound has a wide range of uses and is often used as a key intermediate in the field of organic synthesis. For the preparation of complex organic molecules, it can react with other reagents through a variety of chemical reactions, such as substitution reactions, addition reactions, etc., to build rich carbon skeletons and functional groups, laying the foundation for the synthesis of various drugs and materials.
Furthermore, in the field of materials science, it has also emerged. Or can participate in the polymerization reaction of polymer materials, endow the material with specific properties, such as improving material solubility, thermal stability, etc., and then expand the scope of material applications.
However, this material is also dangerous. When operating, it is necessary to strictly abide by safety procedures, work in good ventilation, and avoid contact with skin and eyes to prevent health hazards.

Physical & Chemical Properties

1 - Ethyl - 4 - Fluorobenzene is also an organic compound. It has unique physical and chemical properties. Looking at its physical properties, at room temperature and pressure, it is a colorless and transparent liquid with a special aromatic odor, which is a common feature of benzene series. Its boiling point is suitable, about a specific temperature range. Due to the intermolecular force, it can be converted from gas to liquid under certain conditions.
In terms of its chemical properties, the conjugated structure of the benzene ring gives it a certain stability. The substitution of ethyl and fluorine atoms makes it have unique reactivity. Fluorine atoms have high electronegativity, which can affect the distribution of electron clouds in the benzene ring, change the density of the adjacent electron cloud, and then affect the activity and position selectivity of the electrophilic substitution reaction. Ethyl can participate in some alkylation-related reactions. This compound can be used as a key intermediate in the field of organic synthesis. With its physical and chemical properties, it participates in a variety of organic reactions to build more complex organic molecular structures.

Technical Specifications & Labeling

1 - Ethyl - 4 - Fluorobenzene is an organic compound, and its preparation process and standards are extremely critical.
To make this product, strict process regulations need to be followed. In the reactor, the corresponding raw materials, such as fluorinated reagents and ethylated reagents, are put into a specific ratio, and the reaction parameters such as temperature and pressure are controlled to make the reaction proceed smoothly. After the reaction is completed, the high-purity product is obtained through multiple separation and purification processes such as distillation and extraction.
Its product specifications also have clear standards. The appearance should be a colorless and transparent liquid without visible impurities. The purity needs to reach a specific value, such as ≥ 99%, to ensure product quality. The impurity content should be strictly limited, such as the content of specific metal ions must be lower than a certain threshold.
During quality inspection, gas chromatography, mass spectrometry and other technologies are used to accurately determine the purity and impurity content of products in order to meet established standards before they can enter the market.

Preparation Method

1 - Ethyl - 4 - Fluorobenzene is an organic compound. The preparation method, raw materials and production process are very important. The selection of raw materials should be precise, such as p-fluorobrobenzene and ethyl magnesium halide can be used as starting materials. In the production process, the reaction steps need to be rigorous. First, the p-fluorobrobenzene and magnesium chips are reacted in anhydrous ether to make Grignard reagent, which is a key step. Then slowly add ethyl halide, stir at controlled temperature to promote its full reaction.
After the reaction is completed, it needs to be post-processed. Washed and dried to remove impurities for purification purposes. Its catalytic mechanism is also important, such as some transition metal catalysts can accelerate the reaction process and increase the yield. The whole preparation process, raw materials, reaction steps and catalytic mechanisms complement each other, all of which are key to the preparation of high-purity 1-Ethyl-4-Fluorobenzene.

Chemical Reactions & Modifications

Today there is a thing called 1-Ethyl-4-Fluorobenzene. In the field of chemistry, its reaction and modification are really the focus of our investigation.
Looking at the reaction, all the conditions and variables affect its direction. The rise and fall of temperature, the presence or absence of catalysts, can make the reaction very different. Or promote its speed, or change its diameter, the beauty of chemistry is fully demonstrated here.
As for modification, it is to increase its characteristics and expand its uses. After modifying the structure, it may have better stability or obtain specific activity. It can be used in medicine and materials industries to develop its talents.
Our chemical researchers, when studying its reaction mechanism, are familiar with the modification method. We hope to be able to control this material, use it for the benefit of the world, and live up to our original intention of studying.

Synonyms & Product Names

1 - Ethyl - 4 - Fluorobenzene, this substance is also in the field of chemical industry, and the investigation of its heteronym and trade name is quite important. Although there is no direct description of this substance in the ancient books of the viewer, it can be found in the present chemical theory.
Or it is called p-fluoroethylbenzene, because its molecular structure, ethyl and fluorine atoms are in the opposite position of the benzene ring. This name directly describes its structural characteristics and is quite commonly used in the industry.
As for the trade name, it may be called another name due to the different uses and production methods. If it is used as a raw material for organic synthesis, the manufacturer may name it according to its characteristics and quality. Although it is not possible to determine the exact trade name of ancient and modern times, it must be related to quality and use in order to show its uniqueness and distinguish it from others.
Today's chemical research is advancing, and the characteristics and applications of 1-Ethyl-4-Fluorobenzene are gradually becoming clear. The detailed examination of its synonym and trade name is also becoming more and more important, which can be used as a reference for the chemical industry to promote its development and refinement.

Safety & Operational Standards

1-Ethyl-4-Fluorobenzene is 1-ethyl-4-fluorobenzene. The following is a passage about its safety and operation specifications in classical Chinese form:
1-ethyl-4-fluorobenzene is a chemical substance. Its characteristics are special, and it is related to safety and operation regulations, so it cannot be ignored.
When hiding, it should be placed in a cool and ventilated place to avoid open flames and hot topics. This substance is flammable, and it is dangerous in case of fire, which can cause flames to ravage and endanger the surroundings. And with oxidants and other substances, when separated, do not mix, to prevent chemical reactions sudden, leading to disaster.
When handling, it is necessary to wear appropriate protective gear. Wear protective goggles to protect your eyes from harm; wearing protective clothing, you can prevent it from hurting your body and skin. And you need to adhere to the order of operation, do not increase or decrease the steps. In a well-ventilated place, the volatile gas will quickly disperse outside, and it will not gather and cause danger.
If you accidentally touch the skin, quickly rinse with plenty of water, followed by soap. If it enters the eye, immediately open the eyelids, buffer with water, and seek medical attention. In case of fire, use dry powder, carbon dioxide and other fire extinguishers to extinguish it, and must not use water to prevent the spread of fire.
In short, the safety and operating standards of 1-ethyl-4-fluorobenzene must be kept in mind and followed to ensure that everything goes smoothly and is safe.

Application Area

1-Ethyl-4-fluorobenzene, this substance is widely used in the field of chemical industry. In the synthesis of materials, it is often used as a raw material to make materials with specific properties. For example, synthesizing polymer materials with special electrical and optical properties can be used in electronic display devices to make their display clearer and more colorful.
In the field of pharmaceutical research and development, it also has important functions. Based on this, it can make a variety of specific drugs, or have antibacterial and antiviral effects, to provide help for the healing of diseases.
Furthermore, in the preparation of fragrances, its unique chemical structure can endow fragrances with different flavors and aromas, which can be used in the preparation of high-end perfumes and fragrances to add unique charm.
All these show that 1-ethyl-4-fluorobenzene is indispensable in many application fields and contributes a lot to the development of various industries.

Research & Development

Today there is a product, named 1-Ethyl-4-Fluorobenzene. I am a chemical researcher, and I have studied its research and development a lot.
This compound has unique chemical properties. Its structure is exquisite, and the order of fluorine and ethyl groups makes its reactivity unique. In the field of organic synthesis, it is often a key raw material.
At the beginning of research, explore the method of its preparation. After repeated attempts, several feasible paths have been obtained. However, in order to seek efficient and environmentally friendly methods, it still needs to be deeply cultivated.
The development path, explore its potential for application. In the creation of medicine, or can be used as an active intermediate to help the research and development of new pharmaceuticals. In materials science, it is also expected to be the cornerstone of new materials.
Although some progress has been made, there is still a long way to go. In the future, we will continue to study, optimize the preparation process, and expand the application scope. It is hoped that it will contribute to the development of the chemical field and make 1-Ethyl-4-Fluorobenzene play a greater value.

Toxicity Research

To study the toxicity of 1 - Ethyl - 4 - Fluorobenzene, this is the priority of chemical research. 1 - Ethyl - 4 - Fluorobenzene is also an organic compound, which has many applications in industry, scientific research and other fields.
After various experiments, it does have an effect on the organism. According to animal experiments, small doses of exposure or slight discomfort caused to the organism, but no significant lesions were found. If exposed to this substance for a long time and in large doses, it can cause damage to the organs, especially the liver and kidneys. Liver, the hub of human metabolism, is damaged by metabolic disorders; kidney, excretion, damage, excretion disorders.
Looking at the cell experiment, 1-Ethyl-4-Fluorobenzene can interfere with the normal physiological function of cells, affect cell proliferation and differentiation, or be related to gene mutation. Therefore, toxicity research has a long way to go, which is related to life and health, and cannot be ignored. It should be investigated in depth to clarify its harm and provide evidence for protection and application.

Future Prospects

In today's world, 1 - Ethyl - 4 - Fluorobenzene is unique in the field of chemistry. Although its current use has been quite extensive, our generation still has unfinished prospects.
In the future, it may emerge in the field of materials science. Its special structure may make it the cornerstone of building new functional materials, opening up new paths for the fields of electronics and optical materials. In pharmaceutical research and development, there are also infinite possibilities. Or through subtle modification, it may become a sharp blade to overcome difficult diseases and benefit the health of all living beings.
Furthermore, with the advance of science and technology, the synthesis process is expected to be greatly optimized. Energy consumption is reduced, productivity is increased, and more environmentally friendly methods will emerge. In this way, 1-Ethyl-4-Fluorobenzene will surely shine in the future, leading the chemical industry to a new peak and living up to the ardent expectations of our researchers.

Where to Buy 1-Ethyl-4-Fluorobenzene in China?

As a trusted 1-Ethyl-4-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Ethyl-4-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Ethyl-4-Fluorobenzene?

1-Ethyl-4-fluorobenzene is also an organic compound. It is widely used in the chemical industry and is mostly used as an intermediary for organic synthesis. Because of its special chemical structure, it can undergo various chemical reactions to derive various useful compounds.
First, in the synthesis of medicine, it is often a key raw material. For example, in the creation of some new drugs, 1-ethyl-4-fluorobenzene can participate in the construction of the basic structure of drug molecules, which in turn endows drugs with specific biological activities and pharmacological effects. Because of its structural characteristics, it can accurately fit the spatial configuration and chemical properties required for drug design, and help to synthesize drugs with high efficiency and low toxicity.
Second, in the field of materials science, it also has important functions. In the preparation of polymer materials with special properties, 1-ethyl-4-fluorobenzene can be introduced into the polymer chain as a comonomer. In this way, the properties of polymer materials can be improved, such as improving the heat resistance, chemical resistance, or optimizing their electrical properties. The introduction of fluorine atoms can change the intermolecular forces and electron cloud distribution of the material, resulting in the material exhibiting unique properties.
Third, in the synthesis of dyes, 1-ethyl-4-fluorobenzene can be used as a starting material to construct colorful and stable dye molecules through a series of chemical reactions. Due to the presence of benzene ring structure and substituents, it can regulate the conjugation system and electron cloud density of dye molecules, thereby affecting the color, photostability and dyeing properties of dyes.
All these, 1-ethyl-4-fluorobenzene, with its unique chemical structure, plays an indispensable role in many fields such as medicine, materials, and dyes, providing an important material basis for the development of various fields.

What are the physical properties of 1-Ethyl-4-Fluorobenzene?

1-Ethyl-4-fluorobenzene is one of the organic compounds. It has unique physical properties, let me tell you one by one.
First of all, under normal temperature and pressure, 1-ethyl-4-fluorobenzene is a colorless and transparent liquid. It is clear in appearance, like a clear spring in the mountains, without suspended impurities. And this liquid is refracted under light, showing a pure state.
As for the boiling point, it is between 155 ° C and 157 ° C. When it is heated, the temperature is gradually approaching this range, and the thermal movement of the molecules intensifies. It gradually changes from liquid to gas and rises in space. This boiling point characteristic is of great practical value when separating and purifying chemical operations. It can be distilled according to the difference in boiling points to obtain pure 1-ethyl-4-fluorobenzene.
In terms of melting point, it is about -60 ° C. When the temperature drops, the molecular movement gradually slows down and the arrangement tends to be orderly. The material solidifies from liquid to solid state, just like water freezes. The change of shape is due to the drop in molecular energy.
In terms of density, it is about 0.99g/cm ³. This density is slightly less than that of water. If 1-ethyl-4-fluorobenzene is mixed with water, it will float on the water surface, just like oil floating on the water, with clear boundaries and no phase fusion.
Solubility is also an important physical property. 1-ethyl-4-fluorobenzene is insoluble in water because its molecular structure is quite different from that of water, and its polarity is different, so it is difficult to dissolve. However, it is soluble in many organic solvents, such as ethanol and ether, just like the same kind of attraction. In organic solvents, 1-ethyl-4-fluorobenzene can be uniformly dispersed to form a uniform solution.
In addition, 1-ethyl-4-fluorobenzene is volatile to a certain extent. In an exposed environment, over time, its amount gradually decreases. And because it is an organic compound, flammable, in case of open flames and hot topics, it is very easy to burn, and the flame is bright. When burning, it releases heat. Therefore, when storing and using, beware of fire sources and place them properly to ensure safety.

Is 1-Ethyl-4-Fluorobenzene chemically stable?

1-Ethyl-4-fluorobenzene is an organic compound. Its chemical stability is related to many chemical and industrial applications. This substance is based on a benzene ring and is connected to ethyl and fluorine atoms in the para-position, respectively.
In terms of its stability, the benzene ring structure has unique stability. The π electron delocalization forms a conjugated system, resulting in a decrease in the energy of the benzene ring and is not easy to participate in the reaction. In 1-ethyl-4-fluorobenzene, ethyl is the power supply group. Although it will increase the electron cloud density of the benzene ring, it has little effect on the overall stability. The fluorine atom has strong electronegativity and can stabilize the benzene ring system when connected to the benzene ring due to its p-π
Under normal temperature and pressure, 1-ethyl-4-fluorobenzene is in a liquid state and has a certain volatility. Usually, it is thermally stable and does not decompose under ordinary heating conditions. However, in case of strong oxidants, such as potassium dichromate, potassium permanganate and other acidic solutions, ethyl may be oxidized to form oxidation products such as carboxyl groups.
Under light or high temperature, 1-ethyl-4-fluorobenzene can undergo free radical substitution reaction. Because the α-hydrogen on the ethyl group is affected by the benzene ring and fluorine atoms, it has a certain activity and can be captured by free radicals, which in turn triggers a substitution reaction.
When encountering electrophilic reagents, 1-ethyl-4-fluorobenzene can undergo electrophilic substitution reaction due to the relatively high electron cloud density of the benzene ring. Both fluorine atoms and ethyl groups are ortho-para-localizers, so electrophilic reagents mainly attack the ortho-and para-sites of the benzene ring to generate corresponding substitutions.
Overall, 1-ethyl-4-fluorobenzene has relatively stable chemical properties, but under specific conditions, such as strong oxidation, light, high temperature or when encountering electrophilic reagents, corresponding chemical reactions can occur.

What are the precautions 1-Ethyl-4-Fluorobenzene in the production process?

1-Ethyl-4-fluorobenzene is an organic compound. During the production process, many matters need to be paid careful attention.
It is flammable and easy to burn in case of open flames and hot topics. Therefore, fireworks must be strictly prohibited in the production site. Hot fire operations must strictly follow safety regulations and implement the approval process. Electrical equipment should also be explosion-proof to prevent accidents caused by electrical sparks.
1-ethyl-4-fluorobenzene may be toxic and potentially harmful to human health. Operators must take protective measures, such as wearing gas masks, protective gloves, protective clothing, etc., to avoid skin contact and inhalation. The production workshop needs to maintain good ventilation and set up an effective ventilation and ventilation system to discharge volatile harmful gases in time and reduce the concentration of harmful substances in the workshop.
This compound is chemically active and reacts under specific conditions or with other substances. When storing and using, it is necessary to prevent it from contacting with strong oxidants, strong acids, strong bases and other substances to avoid violent reactions. During the production process, process parameters such as material ratio, reaction temperature, and reaction time need to be strictly controlled. If there is a slight deviation, it may cause the reaction to go out of control and cause safety accidents.
Furthermore, the storage of materials related to 1-ethyl-4-fluorobenzene cannot be ignored. It should be stored in a cool and ventilated warehouse, away from fire and heat sources, and the warehouse temperature should not exceed 30 ° C. The storage area should be equipped with leakage emergency treatment equipment and suitable containment materials, so that in the event of leakage, it can be handled quickly and properly to prevent the expansion of pollution.
Production equipment needs to be regularly maintained and inspected to ensure that the equipment is free of leakage and operates stably. Regular flaw detection and thickness measurement of equipment such as reaction kettles, pipelines, valves, etc. should be carried out to detect and deal with potential safety hazards in a timely manner.
Caution is also required in the transportation process. It should be carried out in accordance with the relevant regulations on the transportation of hazardous chemicals. Qualified transportation enterprises and vehicles should be selected. Protection and warning signs should be made during transportation to ensure transportation

1-Ethyl-4-Fluorobenzene impact on the environment

1-Ethyl-4-fluorobenzene is one of the organic compounds. Its impact on the environment is quite complex and should be carefully observed.
First, the impact of its physical properties. This compound is volatile, in the atmosphere, or can participate in photochemical reactions. After volatilization, it is mixed into the air, and if inhaled, it may damage the respiratory system. And its vapor diffuses in the air, or interacts with other chemicals to form new pollutants, causing air quality to deteriorate.
Furthermore, on its chemical activity effects. If 1-ethyl-4-fluorobenzene flows into the water body, it is insoluble in water or floats on the water surface, which hinders the gas exchange between the water body and the atmosphere, reduces the amount of dissolved oxygen in the water, and endangers the survival of aquatic organisms. It is in the water, or adsorbed on the suspended particles, and migrates with the water flow, expanding the scope of pollution. If it enters the soil, or is adsorbed on the soil particles, it affects the physical and chemical properties of the soil, hinders the absorption of nutrients and water by plant roots, and causes plant growth to be hindered.
In addition, 1-ethyl-4-fluorobenzene may be bioaccumulative. In the ecosystem food chain, it is ingested by low-level organisms and accumulates in organisms because it is difficult to degrade. With the rise of the food chain, the concentration of high trophic level organisms gradually increases, which may cause changes in the population structure of organisms and disrupt the ecological balance.
Because of its flammability, under specific environments or cause fires, the release of harmful gases, such as fluorinated compounds, also pose a serious threat to the environment and human health.
In summary, 1-ethyl-4-fluorobenzene has an impact on the environment in many aspects. We should treat it with caution to prevent it from polluting the environment and ensure ecological safety.