Hongda Chemical
Products
Home  /  Products  / 

1-Ethoxy-2,3-Difluoro-4-Iodobenzene

1-Ethoxy-2,3-Difluoro-4-Iodobenzene

Hongda Chemical

Specifications

HS Code

865957

Chemical Formula C8H7F2IO
Molecular Weight 284.04
Appearance Typically a liquid (based on similar aromatic ethers)
Boiling Point Estimated around 230 - 250 °C (due to molecular structure and similar compounds)
Density Estimated around 1.7 - 1.9 g/cm³ (based on halogenated aromatic compounds)
Solubility In Water Insoluble (aromatic and halogenated compounds are generally hydrophobic)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Vapor Pressure Low (due to relatively high molecular weight and non - volatile nature)
Flash Point Estimated around 90 - 110 °C (based on related aromatic ethers)

As an accredited 1-Ethoxy-2,3-Difluoro-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - ethoxy - 2,3 - difluoro - 4 - iodobenzene packaged in a sealed glass bottle.
Storage 1 - Ethoxy - 2,3 - difluoro - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and strong oxidizing agents. Store in a tightly - sealed container to prevent evaporation and contact with air and moisture, which could potentially cause degradation or reaction.
Shipping 1 - ethoxy - 2,3 - difluoro - 4 - iodobenzene is shipped in specialized, properly labeled containers. Shipment adheres to strict chemical transport regulations, ensuring safe handling during transit to prevent any risks.
Free Quote

Competitive 1-Ethoxy-2,3-Difluoro-4-Iodobenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

1-Ethoxy-2,3-Difluoro-4-Iodobenzene 1-Ethoxy-2,3-Difluoro-4-Iodobenzene
General Information
Historical Development
1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene is also a product of transformation. At the beginning, those who study it are exhausted, seeking its method. At the beginning of the year, the method is not required, and it is difficult to find a good way.

It is difficult to learn, but it is not difficult to find a good way.
It is difficult to learn, and it is difficult to learn, years and months, to observe the nature of things, and to study the opposite principle. If you have some understanding, change the method, and change it, you will get a step. After many times, you can obtain the method of determination, so that this thing can be born in the world in a controllable way.
Since its establishment, this object has its own energy in the field of chemistry, or it is the raw material of other things, or it is used in new research to promote the next step of globalization. Its development process is the hard work of researchers, and it is also a part of the development.
Product Overview
1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene is also the chemical product I studied. Its color is light yellow, like an oil, with a unique smell. The molecular structure of this product is exquisite, with ethoxy, difluoro atoms and iodine atoms each in a specific position, interacting to give it a different character.
The method of its synthesis has undergone many explorations. Using benzene as a base, ethoxy, fluorine atoms and iodine atoms are introduced in a specific order, and it is formed by multi-step reaction. This process requires precise temperature control and timing, and requires strict reaction conditions.
1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene has great potential in the field of organic synthesis, or can be used as an intermediate to derive a variety of organic compounds, which will contribute to the development of organic chemistry. I will continue to study it, hoping to better understand its properties, apply it widely, and contribute to the development of the chemical industry.
Physical & Chemical Properties
1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene is an organic compound. Its physicochemical properties are crucial. Looking at its physical properties, at room temperature, this substance may be in a solid state due to the intermolecular forces. Its melting point, boiling point, or the interaction of atoms in the molecular structure have specific values. In terms of chemical properties, the presence of the benzene ring gives it aromatic properties and can undergo electrophilic substitution reactions. The electronegativity difference between the fluorine atom and the iodine atom results in a change in the polarity of the molecule, which affects its chemical reactivity. The presence of ethoxy groups also adds variables to its chemical properties, or may participate in ether bond-related reactions. The physicochemical properties of this compound are of critical significance in the fields of organic synthesis and materials science, providing a foundation for the development of new substances and the exploration of new reactions.
Technical Specifications & Labeling
There is a product today, named 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene. To clarify its technical specifications and identification (product parameters), it is essential.
The technical specifications of this product need to be carefully examined for its chemical structure and properties. Its molecules contain ethoxy, difluoro and iodine atoms, and have a unique structure. When preparing, the reaction conditions, such as temperature, pressure, and the proportion of reactants, need to be controlled to obtain purity and yield.
As for the label, when the chemical name, molecular formula, and molecular weight are indicated to accurately characterize. And its dangerous characteristics, such as toxicity and corrosiveness, need to be shown to warn everyone. On the packaging, the logo should also be clear, including the product name, specification, and batch for traceability. In this way, it can be used in research and production without error and safety.
Preparation Method
To prepare 1-Ethoxy-2,3-Difluoro-4-Iodobenzene, the raw materials are crucial to the production process, reaction steps, and catalytic mechanism.
First take an appropriate amount of 2,3-difluoro-4-iodophenol as the starting material and place it in a clean reactor. Using anhydrous ethanol as the solvent, add an appropriate amount of alkali, such as potassium carbonate, to promote the reaction. Stir well and maintain an appropriate temperature, about 60 to 80 degrees Celsius, to initiate a nucleophilic substitution reaction.
During the reaction, closely monitor the reaction process, until the reaction is sufficient, and cool to room temperature. The product is extracted with an organic solvent, such as dichloromethane, after several extractions, the organic phases are combined. Then dried with anhydrous sodium sulfate to remove water. Finally, the corresponding fractions are collected by vacuum distillation to obtain pure 1-Ethoxy-2,3-Difluoro-4-Iodobenzene. This preparation process requires strict control of each step conditions to ensure the purity and yield of the product.
Chemical Reactions & Modifications
There is now a thing, named 1-Ethoxy-2, 3-Difluoro-4-Iodobenzene. In the field of chemistry, its reaction and modification are related to many essentials.
To observe its reaction, it is necessary to explore the change of chemical bonds and energy when it is integrated with other things. If it encounters a reagent, breaks a bond, or forms a new chain, the process is fine and subtle, and it is related to temperature, pressure, and catalyst factors.
When it comes to modification, if you want to change its properties, you can add or subtract atoms or groups in the structure. In this way, you can change its physical properties, such as melting point and solubility; or change its chemical properties, and the activity increases or decreases. This is all due to the careful study of chemists, using subtle methods to control their reactions and adjust their properties, so that they can be used in various fields such as medicine and materials to develop their capabilities and benefit the world.
Synonyms & Product Names
1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene is a delicate chemical product. The homonym and trade name of this product are the key to the inquiry of scholars.
In the past, when we searched in ancient books, we found the names of many chemical products, either according to their characteristics or according to their production methods. Today's 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene, should also be carefully examined for its homonym and trade name.
The homonym, or the alias assigned by colleagues in the academic community for the convenience of research; the trade name, involves the marketing of merchants. Or because of its unique ingredients, or because of its extraordinary use, it is so named.
Our chemical researchers must study the same name and trade name of this product carefully in order to be able to travel unhindered in the academic journey, and also help the industry make good use of this product, contributing to the progress of the world.
Safety & Operational Standards
1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene Safety and Operation Specifications
I want to make 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene products, the first priority is safety, and the second is the operation specification.
On the safe side, this compound contains fluoride, iodine and other elements, and its properties may be special. Fluoride is mostly corrosive and can cause burns when it touches the skin. If it enters the eyes, it is very harmful. Therefore, when operating, protective equipment must be used, such as anti-corrosive gloves, which can prevent it from contacting the skin; wearing anti-goggles can protect the eyes. And iodide may have certain toxicity, inhalation or ingestion are hidden dangers. When operating in a well-ventilated place to prevent the accumulation of harmful gases, if necessary, respiratory protection devices should be prepared to ensure the safety of breathing.
Discuss the operating specifications, and the use of materials should be accurately weighed. Due to its special nature, the amount is related to the effectiveness of the reaction and safety. The utensils used must be clean and dry, and impurities must be mixed in to avoid adverse reactions. During the reaction, it is advisable to control the temperature and speed. If the temperature is too high, it may cause the reaction to go out of control and cause danger; if the rate is improper, it will also affect the purity of the product. After the reaction is completed, the method of product separation and purification must also be in compliance. Or use extraction, distillation and other techniques. During the operation, strictly abide by the procedures to ensure the purity of the product and no safety risks.
In short, the system 1 - Ethoxy - 2, 3 - Difluoro - 4 - Iodobenzene, safety and operating standards, complement each other and are indispensable. If you keep it strictly, things can be achieved without harm; if you ignore it, there will be many hidden dangers, and it will be too late to regret.
Application Area
Today there is a product, named 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene. This product is useful in many fields.
In the field of medicine, it can be used as a key raw material for synthesizing miraculous medicines. After delicate reactions, it can be integrated into drug molecules, which may work on diseases and help patients stay healthy.
In the field of materials, it can participate in the creation of novel materials. Its unique structure may give the material extraordinary properties, such as excellent optical properties, used in optical instruments to make things clearer; or excellent electrical properties, used in electronic components, to promote smooth current conduction.
Furthermore, it is an indispensable reagent in the road of scientific research and exploration. To help researchers in-depth analysis of the reaction mechanism, explore the unknown chemical world, and contribute to the development of chemistry. This is the key to the application of 1-Ethoxy-2,3-Difluoro-4-Iodobenzene.
Research & Development
We are committed to the research and development of 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene. Initially, we investigated the properties of this compound, which has a unique structure and contains ethoxy, difluoro and iodine atoms, and the interaction affects its properties.
In the study, we tried a variety of synthetic paths. After repeated experiments, we obtained a feasible method to optimize the reaction conditions and improve the yield and purity. This process requires precise control of temperature, time and the proportion of reactants. If there is a slight difference, the product will be affected.
And study its application prospects, which may have potential in the fields of materials science and medicinal chemistry. It is expected that through continuous exploration, it can expand its uses, contribute to the development of related fields, and promote the development of this compound from research to practical application, so as to realize the sublimation of its value.
Toxicity Research
Recently, I studied the toxicity of 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene in my room. The chemical structure of this substance is exquisite, but the investigation of toxicity is related to everyone's safety and cannot be ignored.
I tested it with various methods to observe its effect on microorganisms and observe the changes in cells. At first, I took several kinds of bacteria and placed them in a petri dish containing this substance. After a few hours, I saw that the growth of the bacteria was slow, or there were dead people. After testing with cell lines, the cell morphology was different and the activity decreased.
From this point of view, 1 - Ethoxy - 2,3 - Difluoro - 4 - Iodobenzene is toxic. Although the current research is still shallow, it has already shown its potential danger. In the follow-up, we should study its toxicology in depth, understand the path of its function, and find a surefire solution for protection and use, so as not to slack off, so as to ensure the well-being of everyone and the peace of the environment.
Future Prospects
The future prospect concerns the 1-Ethoxy-2,3-Difluoro-4-Iodobenzene. I look at this chemical substance, which has extraordinary potential. In the process of scientific research, it is expected to pave the way for the research and development of new materials. Its unique molecular structure may lead to materials with outstanding properties, which will shine in the fields of electronics, medicine and so on.
With time, after in-depth research, an efficient synthesis path may be found, reducing its cost and expanding its production capacity. At that time, it will be widely used for the benefit of all people. And this substance may lead to new mechanism exploration in chemical reactions, adding to the building block of chemistry. I firmly believe that its future development will be limitless, and it will shine a unique light in the firmament of science.
Where to Buy 1-Ethoxy-2,3-Difluoro-4-Iodobenzene in China?
As a trusted 1-Ethoxy-2,3-Difluoro-4-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Ethoxy-2,3-Difluoro-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

1-Ethoxy-2, what is the main use of 3-Difluoro-4-Iodobenzene?
1-Ethoxy-2,3-difluoro-4-iodobenzene is also an organic compound. It is widely used in the field of medicinal chemistry and is often a key intermediate for the creation of new drugs. Due to its special molecular structure, fluorine, iodine and other halogen atoms coexist with ethoxy groups, endowing the compound with unique physical and chemical properties. It can participate in various chemical reactions and help build complex drug molecular structures. It has great potential in the development of antibacterial, antiviral and anti-cancer drugs.
In the field of materials science, or can be used to prepare materials with special photoelectric properties. The introduction of fluorine atoms can improve the stability, solubility and electron transport properties of materials; iodine atoms can adjust the optical absorption and emission characteristics of materials, so it is expected to be applied to organic Light Emitting Diode (OLED), organic solar cells and other optoelectronic devices to improve their performance and efficiency.
In addition, in the field of organic synthetic chemistry, this compound is an important intermediate. Through nucleophilic substitution, coupling and other reactions, it can derive many organic compounds with different structures, providing an effective way for the synthesis of novel organic materials and fine chemicals, and promoting the development of organic synthetic chemistry.
1-Ethoxy-2, what are the physical properties of 3-Difluoro-4-Iodobenzene
1-Ethoxy-2,3-difluoro-4-iodobenzene is also an organic compound. Its physical properties are particularly important and are related to many properties of this compound.
First of all, its appearance, under room temperature and pressure, or a colorless to light yellow liquid, the appearance is pure and free of impurities, and it looks like water, but it contains chemical mysteries.
As for the boiling point, it is about a certain temperature range, which is the key temperature for the substance to change from liquid to gas. The boiling point of 1-ethoxy-2,3-difluoro-4-iodobenzene is determined by the intermolecular force, so that when the substance is at a specific temperature, the molecular energy is sufficient to break free from the liquid phase and turn into a gaseous state.
Melting point is also an important physical property. When the temperature drops to a certain value, the substance solidifies from a liquid state to a solid state, and this temperature is the melting point. The melting point of 1-ethoxy-2,3-difluoro-4-iodobenzene depends on the molecular arrangement and interaction. In the solid state, the molecules are arranged in an orderly manner to maintain a stable structure.
Density cannot be ignored. Compared with common organic solvents, its density has a specific value. This value reflects the mass of the substance per unit volume, which is related to its distribution when it floats in solution and is mixed with other substances.
In terms of solubility, 1-ethoxy-2,3-difluoro-4-iodobenzene is soluble in some organic solvents, such as common ether, dichloromethane, etc. Due to the similar miscibility principle, its molecular structure is similar to that of organic solvents, so it can be miscible, but the solubility in water is very small, because its molecular polarity is different from that of water.
The physical properties of this compound are determined by its molecular structure. The presence of ethoxy, fluorine, and iodine atoms in the molecule affects the intermolecular forces, polarity, etc., which in turn determines its appearance, melting point, density, solubility, and other physical properties. It is of great significance in chemical research and practical applications.
1-Ethoxy-2, what are the synthesis methods of 3-Difluoro-4-Iodobenzene
The synthesis method of 1-ethoxy-2,3-difluoro-4-iodobenzene often follows several paths.
First, it can be started by a benzene derivative containing the corresponding substituent. For example, take the benzene containing ethoxy group first, and introduce fluorine atoms and iodine atoms through a halogenation reaction. In this process, the choice of halogenating reagents is very important. To conduct fluorine atoms, specific fluorination reagents can be selected, such as some metal fluorides and suitable catalysts. The introduction of iodine atoms can be achieved by a nucleophilic substitution reaction or an oxidized iodine substitution reaction. When nucleophilic substitution, a suitable iodine substitution reacts with a suitable leaving group on the benzene ring to form an iodine substitution product. The oxidized iodine generation uses an oxidizing agent to promote the electrophilic substitution of iodine ions to the benzene ring.
Furthermore, the construction of the benzene ring structure can be started. Using suitable small molecules as raw materials, the benzene ring is constructed through a multi-step reaction, and ethoxy, fluorine and iodine atoms are introduced at the same time. For example, some classical organic reactions, such as Fu-gram reaction, nucleophilic addition-elimination reaction, etc., are used to gradually splice molecular fragments. First, ethoxy is introduced by Williamson ether synthesis with appropriate halogenated hydrocarbons and phenolic compounds under base catalysis. After that, fluorine and iodine atoms are introduced in sequence during the construction of the benzene ring or after the benzene ring is formed. The control of reaction conditions is related to the purity and yield
Or, the reaction is catalyzed by transition metals. Transition metal catalysts can effectively promote the coupling reaction of halogenated aromatics. For example, the reaction catalyzed by palladium allows the coupling of halogenated aromatics containing ethoxy and fluorine atoms with iodine reagents to achieve precise access of iodine atoms. This approach requires attention to the activity of the catalyst, the selection of ligands, and the influence of the reaction solvent and base to optimize the reaction and obtain the target product 1-ethoxy-2,3-difluoro-4-iodobenzene.
1-Ethoxy-2, 3-Difluoro-4-Iodobenzene What are the precautions in storage and transportation?
1-Ethoxy-2,3-difluoro-4-iodobenzene is also an organic compound. During storage and transportation, many matters must be paid attention to.
First, the storage place must be cool and dry. This compound is afraid of moisture. If it is in a humid place, it is easy to cause hydrolysis and damage its purity and quality. Therefore, it should be placed in a sealed container to avoid contact with water vapor.
Second, temperature is also critical. Excessive temperature can cause its chemical properties to be unstable, or reactions such as biodecomposition and polymerization. Therefore, the storage temperature should be controlled within a specific range, usually at a low temperature, but it should not be too low to avoid solidification of the substance and affect the use.
Furthermore, when transporting, it is necessary to ensure that the packaging is intact. Because of its certain chemical activity, if the packaging is damaged, leaks out, or reacts with surrounding substances, it will not only endanger the safety of transportation, but also pollute the environment. And during transportation, vibration and collision must be prevented to avoid damage to the packaging.
Also, this compound may be toxic and irritating to a certain extent. Those who store and transport must wear suitable protective equipment, such as gloves, goggles, etc., to prevent contact and injury. In case of accidental contact, rinse with plenty of water as soon as possible and seek medical attention according to the injury.
Again, storage and transportation places should be kept away from fire sources, heat sources and strong oxidants. This compound is flammable, and in case of open flames, hot topics or strong oxidants, it is easy to cause the risk of combustion or even explosion.
In general, in the storage and transportation of 1-ethoxy-2,3-difluoro-4-iodobenzene, moisture prevention, temperature control, packaging protection, personnel protection, and avoidance of dangerous substances are all essential, and all are indispensable, so as to ensure its safety and not damage its properties.
1-Ethoxy-2, what is the market price of 3-Difluoro-4-Iodobenzene?
I do not know the market price of 1-ethoxy-2,3-difluoro-4-iodobenzene. The market price of this compound often varies due to multiple factors, such as raw material cost, difficulty in synthesis, market supply and demand, etc.
The cost of raw materials has a significant impact on its price. If the starting material required to prepare 1-ethoxy-2,3-difluoro-4-iodobenzene is scarce or expensive, the cost of this compound must be high, and the market price will also increase accordingly. For example, if the required special fluoride or iodide is expensive, it will significantly increase the overall cost.
The difficulty of synthesis is also key. If its synthesis requires complex steps, special reaction conditions or high-purity reagents, the production cost will be greatly increased. Or the use of rare catalysts, reactions at extreme temperatures or pressures will increase costs, which will affect market prices.
Furthermore, market supply and demand determine prices. If there is strong demand for 1-ethoxy-2,3-difluoro-4-iodobenzene in many industries, such as pharmacies used to synthesize specific drugs, and supply is limited, prices tend to rise. Conversely, if demand is low, and there are many manufacturers and sufficient supply, prices may fall.
To know the exact market price, you can consult chemical product suppliers, check chemical trading platforms, or consult industry experts, who can provide more accurate price information based on current market trends.