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What are the main uses of 1-Ethenyl-2- (Trifluoromethyl) Benzene?
1-Vinyl-2 - (trifluoromethyl) benzene, this substance has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Because its structure contains both vinyl and trifluoromethyl, it gives it unique reactivity and properties.
From the perspective of polymerization, vinyl is unsaturated and can be polymerized under appropriate conditions to prepare polymers containing trifluoromethyl side chains. Such polymers exhibit excellent chemical stability, weather resistance and low surface energy due to the presence of trifluoromethyl. All industries such as coatings and plastics require materials with excellent properties. For example, in high-end coatings, the polymer can make the coating more resistant to wear and corrosion, and prolong the service life of the object.
In the field of pharmaceutical chemistry, 1-vinyl-2 - (trifluoromethyl) benzene also has important uses. The introduction of trifluoromethyl can often significantly change the physical and chemical properties, biological activity and metabolic stability of compounds. Drug developers can use it as a raw material to build specific molecular structures and search for lead compounds with high activity and low toxicity.
In the field of materials science, materials based on this substance have emerged in the fields of electronic devices, optical materials and so on. For example, in organic optoelectronic materials, its unique structure can optimize the photoelectric properties of materials and improve the efficiency and stability of devices.
In summary, 1-vinyl-2 - (trifluoromethyl) benzene is an indispensable and important substance in many fields such as organic synthesis, medicinal chemistry, and materials science due to its unique structure, and plays a key role in promoting technological progress and innovation in various fields.
What are the physical properties of 1-Ethenyl-2- (Trifluoromethyl) Benzene?
1-Vinyl-2 - (trifluoromethyl) benzene is one of the organic compounds. Its physical properties are quite important, as detailed below:
First of all, under room temperature and pressure, it is mostly colorless to light yellow liquid. It looks clear and transparent, like glaze, shimmering, and seems to hide endless mysteries. This appearance feature can be used as an important basis for the identification and preliminary cognition of this substance.
As for the smell, it has a special aromatic smell, but its taste is not pleasant and rich, but slightly irritating. Smell it, slightly uncomfortable, this unique smell originates from the interaction of styrene ring and vinyl and trifluoromethyl in its molecular structure.
When talking about the boiling point, it is about a certain temperature range. Because of the intermolecular force, a specific energy is required to overcome this force and convert the liquid phase to the gas phase. The exact value of its boiling point is slightly affected by the environmental pressure, but under standard conditions, it is roughly constant. This characteristic is a key parameter in the process of separation and purification.
In terms of melting point, it also has a specific value. When the temperature drops below the melting point, the substance gradually changes from liquid to solid, and the molecular arrangement tends to be orderly from disorder. Knowing the melting point is crucial in storage, transportation and related process operations.
In terms of solubility, in most organic solvents, such as alcohols, ethers, hydrocarbons, etc., they all have good solubility, just like fish get water, and they blend seamlessly. However, in water, the solubility is extremely small, and the two are like water and fire, which is caused by the difference in molecular polarity.
Density is another important physical property, and its value indicates the mass of a substance per unit volume. Compared with water, the density may be different, and this property is of great significance when it involves operations such as liquid-liquid separation.
In addition, the vapor pressure of 1-vinyl-2- (trifluoromethyl) benzene cannot be ignored. The vapor pressure reflects the difficulty of volatilization of a substance, and its value increases with increasing temperature. In a confined space or a specific reaction environment, changes in vapor pressure may affect the reaction process and safety.
In summary, the physical properties of 1-vinyl-2 - (trifluoromethyl) benzene are diverse and interrelated. They play a key role in many fields such as organic synthesis and chemical production. Knowing their properties can make good use of them and avoid their harm.
What are the chemical properties of 1-Ethenyl-2- (Trifluoromethyl) Benzene?
1-Vinyl-2 - (trifluoromethyl) benzene, this is an organic compound. Looking at its structure, it contains a benzene ring, and the benzene ring is connected with vinyl and trifluoromethyl.
On chemical properties, first, because of the carbon-carbon double bond, it has the typical properties of olefins. Addition reactions can occur. In case of bromine water, the π bond in the double bond is broken, and bromine atoms are added to the carbon atoms at both ends of the double bond, causing bromine water to fade. This addition reaction rate is quite fast. Because of its high electron cloud density of the double bond, it is highly attractive to electrophilic reagents. Under the action of hydrogen in the catalyst, the hydrogenation reaction can occur to form saturated hydrocarbons. This reaction requires suitable temperature and pressure and specific catalysts, such as nickel and palladium.
Second, because trifluoromethyl has strong electron-absorbing properties, it affects the distribution of benzene ring electron clouds. The electron cloud density of the benzene ring decreases, so that the activity of the electrophilic substitution of the benzene ring is weakened. However, due to the relatively high electron cloud density of the ortho and para-sites, the electrophilic substitution reaction still mainly occurs in the ortho and para-sites. For example, when nitration occurs, the nitro group mainly enters the ortho and para-sites of the vinyl group and the trifluoromethyl group.
Third, the α-hydrogen in this compound is affected by the double bond and the tri Under appropriate conditions, substitution reactions can occur, such as when exposed to light or with an initiator, α-hydrogen can be replaced by halogen atoms.
Fourth, the compound has a certain stability, because its conjugate system exists, the energy is reduced. However, the strong electronegativity of trifluoromethyl increases the polarity of the molecule, which affects its physical properties and chemical activity to a certain extent. When encountering strong oxidizing agents, if the conditions are suitable, the carbon-carbon double bond may be oxidized, causing the molecular structure to change.
What are the synthesis methods of 1-Ethenyl-2- (Trifluoromethyl) Benzene?
The synthesis method of 1-vinyl-2 - (trifluoromethyl) benzene, through the ages, many parties have their own wonderful methods, and now they can be described.
One of them can be started from aryl halides. It is obtained by the coupling reaction of aryl halides containing trifluoromethyl with vinyl boric acid or its esters under the action of transition metal catalysts such as palladium catalysts by Suzuki. This reaction condition is mild and the selectivity is quite good. Common palladium catalysts such as tetra (triphenylphosphine) palladium can promote the effective coupling of the two in an alkaline environment. The reaction mechanism is roughly as follows: palladium catalyst is first oxidized with aryl halide to form palladium (ⅱ) intermediate, then metallized with vinyl borate, and finally eliminated by reduction to obtain the target product 1-vinyl-2- (trifluoromethyl) benzene.
Second, through the strategy of phenyne intermediates. Using o (trifluoromethyl) halobenzene as raw material, under the action of strong base, the phenyne intermediate is generated, followed by [2 + 2] cycloaddition reaction with acetylene derivatives, and then subsequent conversion to obtain the desired product. In this process, the selection of strong bases is crucial, and precise selection is required according to the characteristics of the reaction substrate and reaction conditions to ensure the efficient generation of phenyne intermediates and the smooth progress of the reaction.
Third, the nucleophilic substitution path is adopted. If there is a suitable trifluoromethylbenzene derivative with a leaving group on its aromatic ring, it can undergo nucleophilic substitution reaction with vinyl nucleophiles in the presence of appropriate solvents and bases. This method requires fine regulation of the strength and dosage of the reaction solvent and base to achieve the best reaction effect and obtain the target product.
The above synthesis methods have their own strengths and weaknesses, and need to be carefully selected according to the actual situation, such as the availability of raw materials, cost considerations, and the ease of control of reaction conditions.
What is the price range of 1-Ethenyl-2- (Trifluoromethyl) Benzene in the market?
1-Vinyl-2 - (trifluoromethyl) benzene, the market price is difficult to determine. This is due to the influence of many factors, resulting in fluctuations in its price range.
The first to bear the brunt is the trend of supply and demand. If there is a large number of people who need it, and the supply is small, the price will increase; on the contrary, if the supply exceeds demand, the price will go down. If industrial production surges at a certain time, the demand for this product increases greatly, but the output does not keep up, the price may rise.
Furthermore, the price of raw materials is also key. The synthesis of this substance depends on specific raw materials. If the price of raw materials is high and the production cost rises, the price in the market will also be high. If the raw material is abundant and the price drops, the product may also be lowered accordingly.
The process technology is closely related to the production cost. If the process is advanced, the cost can be reduced, and the price of the product may be more competitive; on the contrary, if the process is complicated and the cost is high, the price will not be low.
Market competition also affects its price. If there are many market participants and the competition is fierce, it is a competition for share, or there may be a price reduction. If the market is almost monopolized, the price regulation power is mostly in the hands of the monopolist.
Regional differences cannot be ignored. In different places, the price varies due to different transportation costs, tax policies, and market demand. For those who are transported from afar, the price may be higher than that of local products due to freight, etc.
Therefore, in order to know the exact price of 1-vinyl-2- (trifluoromethyl) benzene, it is necessary to study the market in real time and study the above factors in detail. Due to the changeable market dynamics, the price is also difficult to determine, or fluctuates between tens of yuan per kilogram and hundreds of yuan per kilogram, making it difficult to determine a precise price range.