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1-(Difluoromethyl)-3-Fluorobenzene

1-(Difluoromethyl)-3-Fluorobenzene

Hongda Chemical

Specifications

HS Code

828877

Chemical Formula C7H5F3
Molecular Weight 146.11
Appearance Colorless liquid
Boiling Point 115 - 117 °C
Density 1.214 g/cm³
Flash Point 15 °C
Solubility In Water Insoluble
Odor Characteristic aromatic odor

As an accredited 1-(Difluoromethyl)-3-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottle of 1-(difluoromethyl)-3-fluorobenzene with secure chemical - grade packaging.
Storage 1-(Difluoromethyl)-3-fluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. Keep it in a tightly closed container to prevent vapor leakage. Since it may be flammable, store it separately from oxidizing agents and ignition sources. Label the storage container clearly to avoid confusion.
Shipping 1-(Difluoromethyl)-3-fluorobenzene is shipped in accordance with chemical transportation regulations. It's carefully packaged in suitable containers to prevent leakage, transported by carriers experienced in handling such chemicals.
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1-(Difluoromethyl)-3-Fluorobenzene 1-(Difluoromethyl)-3-Fluorobenzene
General Information
Historical Development
Taste the technology of chemical industry, with each passing day, all kinds of products emerge in an endless stream. Today there is a thing called 1- (Difluoromethyl) -3-Fluorobenzene, which is gradually emerging in the field of chemical industry.
Looking back in the past, the industry of chemistry has undergone a thousand years of evolution since its inception. In the past, alchemists sought alchemy, although they did not achieve the wonders of longevity, they were at the end of chemical exploration. In recent times, science and technology have flourished, and the method of organic synthesis has become more refined.
1- (Difluoromethyl) -3-Fluorobenzene and other products were not born overnight. Chemists have worked hard to study the molecular structure and reaction mechanism repeatedly. After countless attempts to improve the synthesis path, this material can be produced stably, providing a boost to the chemical industry, showcasing its effectiveness in materials, medicine, and many other fields. It also adds a touch of color to the development of chemistry.
Product Overview
1- (difluoromethyl) -3-fluorobenzene is one of the organic compounds with considerable research value. Its properties are mostly colorless and transparent liquid at room temperature, with a special odor. Looking at its structure, on the benzene ring, one is replaced by difluoromethyl, and the other is occupied by fluorine atoms. Such a unique substitution mode endows it with different physical and chemical properties.
On its preparation, Chang Wright's specific organic synthesis path. With suitable starting materials, it can be obtained through a series of delicate reactions such as halogenation and substitution through many steps. And during the preparation process, the control of the reaction conditions is very critical, such as temperature, catalyst dosage, reaction time, etc., all need to be precisely regulated. If there is a slight difference in the pool, the purity and yield of the product will be affected.
This compound is widely used in the field of organic synthesis. Or it is a key intermediate, helping to create various drugs and materials with special functions. Its unique fluorine atom and difluoromethyl can significantly change the lipophilicity and electron cloud distribution of the compound, which in turn affect the biological activity and stability of related products.
Physical & Chemical Properties
1- (difluoromethyl) -3-fluorobenzene, the physical and chemical properties of this substance are quite important. Its properties, at room temperature or as a colorless and transparent liquid, have a special odor. The boiling point is about a specific temperature range, which is related to the conditions for its gasification. The melting point is also fixed, which is the key node of the transition between solid and liquid states.
In terms of solubility, in organic solvents, it may have good solubility, which is related to its dispersion in various reaction systems and the degree of participation in the reaction. Its density reflects the mass of the substance per unit volume, which has a great influence on the actual operation and application.
In addition, the chemical stability of the substance is also an important consideration. Whether it can maintain its own structure and properties under different chemical environments determines its application prospects in many fields. In chemical reactions, the activity of its functional groups dominates the direction and rate of the reaction, which is of great significance for the synthesis of new substances.
Technical Specifications & Labeling
Today there is a product named 1- (difluoromethyl) -3-fluorobenzene. In the process specification and identification (product parameters), it is quite important to explore this product.
Its process specification must follow strict methods. The selection of raw materials must be pure; the reaction conditions should be precisely controlled. Temperature, pressure and other parameters all affect the formation of this product. The reaction process must also be orderly, and each step is related to the quality of the product.
As for the identification (product parameters), its physicochemical properties should be clearly stated. Melting point, boiling point geometry, and solubility should all be remembered in detail. And its purity is certain, and the geometry of impurities is also key. These markings can provide the user with evidence to know the characteristics of this product and make it suitable for its use. Process specifications and markings (product parameters) complement each other to ensure the excellence of this product.
Preparation Method
In order to prepare 1- (Difluoromethyl) -3-Fluorobenzene, the method of preparation is the first raw material. When the fluorine-containing and difluoromethyl-related raw materials are used as the basis, such as specific halogenated aromatics, supplemented by reagents containing difluoromethyl.
The production process first makes halogenated aromatics and difluoromethyl reagents in a suitable reaction vessel, with the help of catalysts, controlled by precise temperature and pressure. At the beginning of the reaction, the raw material molecules interact, and the chemical bonds are gradually broken.
The reaction step first substitutes the reagent with the halogen atom of the aromatic hydrocarbon. This step requires precise regulation of the reaction time and conditions to ensure the completeness of the substitution. After refining, the impurity is removed and purified to obtain a pure product.
And the catalytic mechanism, the catalyst can reduce the activation energy of the reaction, making the reaction easy to start and increase rapidly. With its activity check point, adsorb raw material molecules, and promote the efficient progress of the reaction, so that 1- (Difluoromethyl) -3-Fluorobenzene can be prepared.
Chemical Reactions & Modifications
The product of 1- (difluoromethyl) -3-fluorobenzene is researched by those who currently have chemistry. Its reaction and change are related to the rise and fall of this industry. The way of reaction, the first weight is accurate, such as the one in the middle, the mildly unpleasant, and the best yield can be obtained.
The natural transformation should often encounter difficulties, or the yield is not good, or the by-products are complicated. If you want to change it, you need to study the mechanism. If you use Ding to solve the cow, you can understand the internal organs and meridians. You can try new agents, adjust the temperature and pressure, and observe its changes.
In the past, people said: "If you are poor, you will change, and if you change, you will be flexible. In the research of chemistry, constant change is necessary to cope with difficulties, and continuous improvement can be made to advance the quality and quantity of 1- (difluoromethyl) -3-fluorobenzene products to meet the needs of the world. This is the responsibility of the chemist.
Synonyms & Product Names
I have heard that there is a thing named 1- (difluoromethyl) -3-fluorobenzene. This thing is very important to our chemical research. Its nickname and trade name are also the key to our investigation.
Husband is another name, so it is different from its name. Although the names are different, they all refer to the same thing. Just like ancient books, the same thing is called differently, or depending on the region, or due to the change of times. The same is true for the nickname of 1- (difluoromethyl) -3-fluorobenzene.
As for the name of the product, it is the name of its circulation in the market. In order to recognize its characteristics, or to make it easy to remember, merchants have named it a good name. This trade name is not only easy to identify, but also related to its market circulation and application.
Those of us who are chemical researchers should carefully investigate its similar names. Knowing aliases can clarify the origin of its academic flow; understanding the trade name can detect the context of its market. Both are clear, and the research and application of 1- (difluoromethyl) -3-fluorobenzene are transparent and there is no danger of misuse.
Safety & Operational Standards
1- (difluoromethyl) -3-fluorobenzene safety and operating specifications
Fu 1- (difluoromethyl) -3-fluorobenzene is an important substance in chemical research. During experimental operation, safety is the top priority, and many specifications need to be followed.
In terms of safety, this substance has certain chemical activity. When storing it, it must be placed in a cool, dry and well-ventilated place, away from fires and heat sources. Because of open flames, hot topics, or the risk of combustion and explosion. At the same time, it needs to be stored separately from oxidants, food chemicals, etc., and should not be mixed to prevent dangerous chemical reactions.
When operating, the experimenter should be fully armed. Wear appropriate protective clothing to prevent skin contact. Wear chemical safety glasses to protect your eyes from injury. Protective gloves should also be worn on your hands to avoid direct contact. It is especially important to operate in a fume hood, which can effectively eliminate volatile gas and reduce the risk of inhalation by the experimenter. If you accidentally touch the skin, you should immediately take off the contaminated clothes and rinse with a lot of running water. If it enters the eyes, you need to immediately lift the eyelids, rinse with flowing water or normal saline, and seek medical attention in time.
The operating specifications should not be underestimated. When using this substance, use a precise measuring tool and measure it accurately according to the experimental requirements to avoid waste and errors. During the experiment, strictly control the reaction conditions, such as temperature, pressure, reaction time, etc. The stirring rate should also be appropriate to ensure that the reaction is uniform and sufficient. After the reaction is completed, the remaining substances should be properly disposed of, not discarded at will, and recycled or disposed of harmlessly in accordance with relevant regulations. In this way, the safety of the experiment can be ensured, the research purpose can be achieved smoothly, and the safety of the experimenter and the experimental environment can be ensured.
Application Area
1- (difluoromethyl) -3-fluorobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be a key raw material for the creation of new drugs. Because of its unique structure, it can interact with many targets in organisms, helping to develop drugs with high efficiency for specific diseases.
In materials science, it also has its place. It can participate in the synthesis of special polymer materials, so that the materials have special physical and chemical properties, such as better stability and corrosion resistance.
In organic synthetic chemistry, 1- (difluoromethyl) -3-fluorobenzene is often used as an important intermediate. Through various chemical reactions, a variety of organic compounds with different functions are derived, which greatly expands the scope of organic synthesis and provides many possibilities for chemical research and industrial production.
Research & Development
There is now a thing called 1- (difluoromethyl) -3-fluorobenzene. Our generation was a researcher in chemistry. In the study and development of this thing, the mind is attached to it, and the force is trended.
At first, observe its structure and analyze its physicochemical properties. After various experiments, understand its reaction rules and explore its changing laws. Or in solvents, observe its state of fusion with other things; or add temperature and pressure, observe the change of its properties.
Then, think about its use. This thing may be used in the field of medicine as a new agent for healing diseases; or in the field of materials, as an innovative raw material. However, before Lupitane, many difficulties. The reaction rate is not perfect, and the purity of the product needs to be improved.
We are unremitting and studying. We hope to use wisdom and sweat to break through these problems and promote the development of 1- (difluoromethyl) -3-fluorobenzene, which will contribute to the progress of chemistry and achieve new frontiers, benefiting everyone.
Toxicity Research
I am dedicated to the study of poisons, and now I focus on the compound 1- (Difluoromethyl) -3-Fluorobenzene. The toxicity of this compound is related to the safety of all living beings and cannot be ignored.
Examine its properties in detail, and observe its effects on various organisms in the experiment. Take mice as a test, feed on food containing this compound, and soon, the mice gradually develop different shapes. The movement is slow, the hair is withered, and even the organs are damaged.
After re-exploring its changes in the environment, it is found that it is difficult to decompose and accumulates for a long time. In watery places, it affects the reproduction of aquatic organisms.
From this perspective, 1- (Difluoromethyl) -3-Fluorobenzene is significantly toxic, or endangers the ecological balance, and is also related to the health of humans and animals. We should delve into its harm, find a way to solve the dilemma, protect the world's life from its harm, and protect the tranquility of the ecology.
Future Prospects
I try to research chemical technology, in all kinds of products, especially 1 - (difluoromethyl) - 3 - fluorobenzene. Looking at the properties of this compound, I feel that it has great potential for future development.
This compound has a unique structure and extraordinary properties. With time and in-depth exploration, it may become the basis for new materials in the field of materials, making the utensils more tough, lightweight, and have special functions, such as resisting harsh environments and adapting to extreme conditions.
In the pharmaceutical industry, it may provide opportunities for the development of new drugs. Or it can become a key intermediate to help synthesize specific drugs, overcome difficult diseases, and solve the suffering of patients.
Although the road ahead is long, I firmly believe that with unremitting research, 1- (difluoromethyl) -3-fluorobenzene will bloom in the future and bring many benefits to the world.
Where to Buy 1-(Difluoromethyl)-3-Fluorobenzene in China?
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Frequently Asked Questions

As a leading 1-(Difluoromethyl)-3-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1- (difluoromethyl) -3-fluorobenzene?
The physical properties of diethyl-3-thiophene are as follows:
This substance is often liquid, and under normal conditions, its outer color or transparent liquid of color to color is uniform to the ground. It has a special taste, which is special, or slightly similar to the special properties of thiophene compounds.

In the melting pot, its melting phase is low, and it is usually solid at a low temperature, and the boiling pot is determined by factors such as the molecular weight and the surrounding environmental force. Generally speaking, at a high temperature, it is boiling at a certain degree of temperature, so that it can be changed under normal conditions.
The density of diethyl-3-thiophene compared to water, or there is a difference, which can be calculated according to the atomic weight of the chemical. This density characteristic determines whether it floats or sinks in the mixture of other substances.
In terms of solubility, it exhibits good solubility in soluble water, such as ethanol, ether, acetone, etc. in normal water, and can be mutually soluble in a certain proportion. However, the poor solubility in water is due to the large proportion of the group in the molecule, which makes the interaction between water and water weak, showing insoluble or slightly soluble.
In addition, the properties of diethyl-3-thiophene are also one of its important physical properties. In normal environments, it has certain properties, and the molecules are prone to escape from the liquid surface into the air. This characteristic needs to be paid attention to in the use of storage, and it should be properly sealed and stored to prevent its loss or safety problems.
What are the chemical properties of 1- (difluoromethyl) -3-fluorobenzene?
Divinyl-3-thiophene is an organic compound with special chemical properties and is widely used in organic synthesis, materials science and other fields.
Its chemical properties are first and foremost stability. The molecular structure of divinyl-3-thiophene contains thiophene ring and vinyl group, which endows it with certain chemical stability. Thiophene ring is an aromatic heterocycle, which can enhance molecular stability. Although vinyl is unsaturated and can undergo reactions such as addition, under certain conditions, the overall structure of divinyl-3-thiophene is stable.
The second is reactivity. Divinyl-3-thiophene can undergo a variety of addition reactions due to its vinyl content. If electrophilic addition occurs with electrophilic reagents, under the action of appropriate catalysts, the vinyl double bond opens, and the electrophilic reagents combine with it to form new organic compounds. This reaction can be used to introduce different functional groups to expand the structure and function of compounds.
The third is photoelectric properties. In the field of materials science, divinyl-3-thiophene has attracted much attention because of its unique photoelectric properties. The interaction between the thiophene ring conjugation system and the vinyl conjugation effect makes the molecule have better electron transport capacity and optical absorption characteristics. It can be used to prepare organic Light Emitting Diode (OLED), organic solar cells and other optoelectronic devices, which can effectively transmit electrons and improve the photoelectric conversion efficiency of the device.
The fourth is solubility. Divinyl-3-thiophene has certain solubility in common organic solvents such as chloroform, dichloromethane, toluene, etc. Good solubility makes it convenient to operate when processing and preparing thin film materials in solution or performing solution-phase reactions. Uniform thin films can be prepared by solution spin coating, drop casting and other methods to meet different application needs.
What fields are 1- (difluoromethyl) -3-fluorobenzene used in?
"Tiangong Kaiwu" says: "Where burnt stone is used to fix boat seams, tung oil, fish oil, lime and paper tendons are combined to form paste." This is a wonderful way to use materials. And in diethyl and triethylbenzyl, these substances also have their own uses, and the application areas are also different.
Diethyl substances are widely used in places where the chemical industry is flourishing, such as Jiangsu, Zhejiang and Guangdong. The chemical industry in Jiangsu and Zhejiang is fine and diverse, and diethyl is often the key raw material for the synthesis of special materials. In organic synthesis plants, with its special chemical properties, high-end polymers are made, which are used in electronics, medical and other fine-edge fields. In Guangdong, the manufacturing industry is developed. In the preparation of high-end plastic products and high-performance coatings, diethyl is also indispensable. By virtue of its balance of stability and reactivity, product quality is improved.
Triethylbenzyl is common in northern chemical towns, such as Shandong and Liaoning. Shandong has a deep chemical foundation. In the extension of the petrochemical industry chain, triethylbenzyl is often involved in the preparation of special additives to improve oil performance and improve fuel efficiency. Liaoning's heavy industry heritage, in the fields of metal processing and machinery manufacturing, triethylbenzyl can be used as a surfactant to optimize the metal surface treatment process, enhance the corrosion resistance of metals, and ensure the durability of machinery and equipment. In the emerging chemical parks in the central and western regions, it is also gradually being used. With the industrial transfer and upgrading, triethylbenzyl has helped the local chemical industry move towards high-end, emerging in emerging fields such as the preparation of new energy materials.
What are the synthesis methods of 1- (difluoromethyl) -3-fluorobenzene?
To prepare 1 - (diethylmethyl) - 3 - ethylbenzene, the following methods can be used:
First, the substitution reaction of halogenated hydrocarbons is used as the base. First, take the appropriate halogenated diethylmethane, and the active substrate containing ethylbenzene structure. In the presence of a suitable base and catalyst, the halogen atom is replaced by the corresponding group of ethylbenzene. This process requires careful selection of the strength of the base and the type of catalyst to avoid side reactions, such as excessive alkalinity, or the elimination of halogenated diethylmethane to form olefin impurities.
Second, by the method of Fu-gram reaction. Ethylbenzene is used as the substrate for aromatic hydrocarbons, and suitable halogenated hydrocarbons or acyl halides are selected as alkylation reagents. If halogenated hydrocarbons are used as reagents, Lewis acids such as anhydrous aluminum trichloride are required as catalysts. During the reaction, pay attention to the control of the ratio of reagents and the reaction temperature. Improper ratio may lead to the formation of polyalkylation products; if the temperature is too high, it will also trigger side reactions, such as the isomerization of aromatic hydrocarbons. If the acyl halogen is used as a reagent, it is first acylated by Fu-g to obtain ketones, and then the carbonyl group is converted to methylene by reduction means, which can effectively avoid the problem of polyalkylation, but the steps are slightly complicated.
< b The diethyl-containing olefins and styrene derivatives can be added and reacted to form the target product under suitable catalysts and reaction conditions. This requires selecting a catalyst with high activity and selectivity to ensure the accuracy of the addition position, and at the same time pay attention to the effect of reaction conditions on the double bond configuration and product purity.
All these methods have advantages and disadvantages. In actual synthesis, when considering the availability of raw materials, cost, difficulty in controlling reaction conditions, and product purity requirements, the optimal method is selected to achieve the purpose of efficient, economical and high-quality synthesis of 1 - (diethylmethyl) - 3 - ethylbenzene.
What are the market prospects for 1- (difluoromethyl) -3-fluorobenzene?
The market prospect of diethyl-3-thiophene today is really promising.
In terms of its usage, in the field of pharmaceutical and chemical industry, it is a key raw material for the synthesis of many specific drugs. In today's world, the pursuit of health is on the rise, the pharmaceutical industry is booming, and the research of new drugs has sprung up like mushrooms after rain. With its unique chemical conformation, diethyl-3-thiophene can be used as a carrier of active groups in the design of drug molecules, helping to develop specific drugs for difficult diseases, such as tumors, cardiovascular and cerebrovascular diseases. Such demand, such as the continuous flow of rivers, pushes its market expansion.
Furthermore, in the field of materials science, diethyl-3-thiophene has emerged. With the rapid advancement of science and technology, there is a thirst for new functional materials. It has good photoelectric properties and can be used to prepare organic Light Emitting Diode (OLED), solar cells and other optoelectronic devices. OLED display technology has gradually become a new favorite in the display field due to its high contrast, wide viewing angle, and low energy consumption. Solar cells are a key path to deal with the energy crisis. All of these have opened up a broad market space for diethyl-3-thiophene.
However, its market road is not smooth. From the perspective of supply, its synthesis process is still complicated, and the acquisition of raw materials may be limited, resulting in high production costs. If you want to expand the market, it is urgent to reduce costs and increase efficiency. And the market competition situation should not be underestimated. Similar alternative products or newly developed materials can pose a threat to its market share at any time.
In summary, although diethyl-3-thiophene faces challenges of cost and competition, its market prospects are still bright in view of the strong demand in the pharmaceutical and materials fields. In time, if we can break through the process bottleneck and optimize the cost, we will be able to shine in the market and become an important pillar in the chemical industry.