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1-(Difluoromethoxy)-4-Nitrobenzene

1-(Difluoromethoxy)-4-Nitrobenzene

Hongda Chemical

Specifications

HS Code

754490

Chemical Formula C7H5F2NO3
Molecular Weight 189.12
Appearance Solid
Boiling Point N/A
Melting Point N/A
Density N/A
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point N/A
Vapor Pressure N/A
Stability Stable under normal conditions
Hazardous Nature May be harmful if swallowed, inhaled or in contact with skin

As an accredited 1-(Difluoromethoxy)-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1-(difluoromethoxy)-4-nitrobenzene packaged in a sealed, chemical - resistant bottle.
Storage 1-(Difluoromethoxy)-4-nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly - sealed container to prevent leakage. Store separately from oxidizing agents, reducing agents, and other reactive substances to avoid potential chemical reactions.
Shipping 1-(Difluoromethoxy)-4-nitrobenzene is shipped in sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling, handling, and transport to prevent any leakage or safety risks.
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1-(Difluoromethoxy)-4-Nitrobenzene 1-(Difluoromethoxy)-4-Nitrobenzene
General Information
Historical Development
There is also a reason for the popularity of this product, Difluoromethoxy-4-Nitrobenzene. In the past, the Fang family studied the field of chemistry and wanted new products to meet all the needs.
At the beginning, scholars worked hard to explore the preparation method. After countless attempts, or in the reaction conditions, or in the selection of raw materials. There are signs of gradual development.
Over the years, the preparation method has become more and more refined, and the yield has gradually increased. Its use has gradually become known to everyone, and it has made its mark in medicine, materials and other industries. From the initial difficult creation to the wide application, it is like a prairie fire, burning more and more intense. Looking at its historical evolution, it is the cohesion of the efforts of various chemical sages, which has promoted this product to continue to move forward in the torrent of the times and bloom.
Product Overview
1- (difluoromethoxy) -4-nitrobenzene has a yellowish color, resembles an oil, and has a special odor. The melting point of this compound is quite low, and it is a flowing state at room temperature. In its molecular structure, difluoromethoxy and nitro are separated from the benzene ring, giving it unique chemical activity.
In chemical reactions, 1- (difluoromethoxy) -4-nitrobenzene exhibits active properties. The nitro group on the benzene ring reduces the electron cloud density of the benzene ring, making it more vulnerable to nucleophilic attack. The presence of difluoromethoxy affects the reaction activity and selectivity. It can be used in many organic synthesis reactions and is an important intermediate for the preparation of complex organic compounds.
However, it should be noted that this substance is toxic and irritating. When operating, follow strict safety procedures and operate in a well-ventilated place to prevent endangering the health of the experimenter.
Physical & Chemical Properties
1- (difluoromethoxy) -4-nitrobenzene, its physical and chemical properties are quite critical. This compound, depending on its morphology, may be solid at room temperature, with a specific color and texture. When it comes to melting point, it begins to melt in a specific temperature range after fine determination, which has a great impact on its application in different scenarios. The boiling point also has its own number. Under a specific pressure, it reaches a certain temperature and boils, which is related to its separation and purification operations.
In terms of solubility, it may exhibit different solubility properties in a variety of common organic solvents. In water, the degree of solubility is limited, due to the hydrophobic part of the structure. In terms of chemical activity, due to the presence of nitro and difluoromethoxy, it is easy to participate in specific reactions. Nitro has strong electron absorption, which changes the electron cloud density of the benzene ring and is easy to induce electrophilic substitution reactions. Difluoromethoxy gives it unique chemical and physical properties. It is an important intermediate in the field of organic synthesis. In-depth exploration of its physical and chemical properties is of far-reaching significance for chemical research and industrial production.
Technical Specifications & Labeling
Today there is a thing called 1- (Difluoromethoxy) -4-Nitrobenzene. If you want to clarify its technical specifications and labels (product parameters), you should check it carefully.
The technical specifications of this thing are related to its quality, its quantity, and its nature. Quality, purity or not, and the geometry of impurities need to be clear. Those who measure accurately, it is not pleasant. For sex, physical and chemical properties are all key. Physical properties such as melting point, boiling point, solubility, etc., and the reaction characteristics of various substances should be detailed.
As for the logo, when it has its name, the name of 1- (Difluoromethoxy) -4-Nitrobenzene cannot be mistaken. And it should be marked with its origin and batch to make it traceable. It is also necessary to show safety signs, such as toxic, non-toxic, flammable or not, to warn everyone and ensure the safety of the user. In this way, the gist of the technical specifications and labels of this thing can be obtained.
Preparation Method
The method of preparing 1- (difluoromethoxy) -4 -nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are prepared with specific difluoromethylation reagents and p-nitrophenol as the starting point. During the reaction, a catalyst is added to a reaction kettle at a suitable temperature and adjusted to a suitable pH. The two are put into the kettle in sequence and stirred to fully blend. After the reaction has passed for several days, the progress of the reaction is closely checked. After the reaction is completed, the product is purified by extraction, distillation and other methods. In this way, through delicate raw material compatibility, orderly reaction steps and appropriate catalytic mechanisms, 1- (difluoromethoxy) -4-nitrobenzene can be obtained. The method of this preparation is fine and orderly, which is crucial to chemical technology.
Chemical Reactions & Modifications
Modern chemistry has advanced, and many new compounds have been derived. Compounds such as 1- (Difluoromethoxy) -4-Nitrobenzene have also entered our research field. Its chemical reaction and modification are really the most important.
Looking at this compound, during the reaction, the conditions are slightly different, and the product changes. To obtain good results, it is necessary to study the temperature, pressure, catalyst, etc. of the reaction. When modifying, the purpose is to adjust its properties and increase its usefulness. Or change its structure, add or subtract groups, in order to change its solubility, heat and chemical stability.
We should study the secret of the reaction and modification of this compound in a rigorous state, and hope to contribute to the advancement of chemistry and industry, and contribute a small amount of power to open up new frontiers and benefit the world.
Synonyms & Product Names
1 - (difluoromethoxy) -4 -nitrobenzene, which has attracted much attention in our chemical research. Its aliases and trade names are also the main points of research.
According to its various names, aliases, such as benzene with difluoromethoxy and nitro groups, are named according to their chemical structure characteristics. Trade names are related to market circulation, or vary depending on manufacturer promotion and product characteristics.
Our generation found it in ancient books. Although it is difficult to find the exact name of the same thing, it is chemically reasonable, or can be analogous to the description of specific structural compounds in the past. Today's 1 - (difluoromethoxy) -4 -nitrobenzene, its alias and trade name are important in research, production and trade. By stating its name, it can be confirmed, avoid the risk of confusion, and benefit academic exchanges and industrial production. This is an indispensable task for chemical research.
Safety & Operational Standards
1 - (difluoromethoxy) - 4 - nitrobenzene, this chemical is crucial to safety and operating standards.
Manufacture this chemical, in the room, the first priority is environmental safety. All instruments must be clean and in good condition, without the risk of damage, to prevent leakage. Ventilation equipment should also be well-developed, so that indoor turbid gas can be discharged in time to keep the air fresh and avoid the accumulation of toxic gases.
When operating, all steps should be in accordance with precise regulations. When using raw materials, use a precise gauge, and there must be no mistakes. When mixing, the speed of stirring and the control of temperature are all fixed. If the temperature is too high, it may cause excessive reaction and cause danger; if the stirring is uneven, the product is impure.
And personnel protection should not be ignored. Special protective clothing must be worn to resist chemical erosion; wear a protective mask to protect the eyes and nose from toxic gas entering the body.
When storing, it is advisable to choose a cool and dry place, away from fire and heat sources. Seal must be tight to prevent contact with air, moisture, etc., causing deterioration or dangerous reactions.
When handling, also be cautious. Handle with care to avoid collisions and bumps, and prevent package damage and leakage.
All of these are regulations for the safety and operation of 1- (difluoromethoxy) -4-nitrobenzene. Practitioners must keep them in mind and practice them effectively to ensure that everything goes smoothly and there is no safety risk.
Application Area
Today there is a thing called 1- (Difluoromethoxy) -4-Nitrobenzene, which is of great value in various application fields. In the field of pharmaceutical research and development, it may be the key raw material for the creation of new drugs. With its unique chemical structure, it may be able to derive drugs with extraordinary curative effects to cure various diseases. In the field of materials science, it may also be able to help the research and development of special materials. With its characteristics, the materials have different properties, such as better stability or special optical properties. Although not widely known, its potential cannot be underestimated. With time and in-depth research, it will be able to shine in the application fields of medicine, materials, etc., for the well-being of the world, and promote the progress and development of related fields.
Research & Development
Yu Taste is dedicated to the research of chemical products, and recently focused on 1- (Difluoromethoxy) -4-Nitrobenzene. Its research and development are related to many aspects.
At the beginning, explore its synthesis method. After repeated experiments, several feasible paths were found. However, in order to seek efficient and environmentally friendly methods, further research is still needed. In the optimization of reaction conditions, the choice of temperature, pressure and catalyst is the key.
Furthermore, consider its properties. Its physical and chemical properties determine its application scope. Studying its stability, solubility, etc., can show its performance in different environments.
As for the development prospects, if we can improve the synthesis process, improve the yield and purity, there will be a vast world in the fields of medicine, materials and so on. I will make unremitting efforts to promote the research and development of this product and contribute to the field of chemistry.
Toxicity Research
1- (Difluoromethoxy) -4-Nitrobenzene Toxicity Study
The nature of the compound is related to the health of people's livelihood and cannot be ignored. Today's research on 1- (Difluoromethoxy) -4-Nitrobenzene, the toxicity of this substance is particularly important.
In the experiment, take all kinds of creatures as a test to observe their state of being affected by this substance. See mice suffer from it, or they may show signs of slow movement, reduced eating, or even dull hair and listlessness.
Investigate the reason, or because the substance enters the body, it disturbs the order of its biochemistry. Cell metabolism is blocked, and visceral functions are also damaged. For example, the liver, which is a detoxification officer, encounters this poison, the metabolic burden increases and its function gradually weakens.
Also think about if this substance flows into the world, enters rivers, lakes and seas, or causes death to aquatic things. Algae growth is inhibited, the food chain is broken, and the ecology is in danger.
Therefore, the study of its toxicity cannot be slack. I hope to get a complete theory, so as to understand its harm, avoid disasters for the world, and keep all things healthy.
Future Prospects
1- (Difluoromethoxy) -4-Nitrobenzene is a chemical substance that we have studied deeply. Looking at this substance, it is unique in nature and exquisite in structure, and has a broad prospect for future development.
In today's world, science and technology are new, and the field of chemistry is also booming. 1- (Difluoromethoxy) -4-Nitrobenzene is expected to shine in medicine and materials. For medicine, it may be possible to use its characteristics to develop new agents to treat various diseases and save people from diseases and pains. For materials, it may be able to help form new materials to make utensils stronger and more clever, and meet all needs.
Our researchers should be diligent in delving into the nature of this thing and exploring its uses. With time, we will be able to open up new frontiers and make 1- (Difluoromethoxy) -4-Nitrobenzene on the stage of the future, show its outstanding ability, contribute to the progress of the world, and contribute to the unfinished business, which is what my generation expects.
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Frequently Asked Questions

As a leading 1-(Difluoromethoxy)-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1- (difluoromethoxy) -4-nitrobenzene?
1 - (diethylamino) -4 -cyanobenzene, this is a class of organic compounds. Its main uses are quite extensive. In the field of medicinal chemistry, it is often used as a key intermediate to assist in the synthesis of many drug molecules with specific biological activities. For example, when developing anti-tumor drugs, their structural properties can be chemically modified to fit the target of tumor cells and achieve precise treatment.
In the field of materials science, it also plays an important role. It can be used to prepare functional materials with special optical or electrical properties. Like some organic optoelectronic materials, with the unique molecular structure of 1- (diethylamino) -4-cyanobenzene, it can exhibit excellent fluorescence characteristics or charge transport ability, and then be applied to organic Light Emitting Diode (OLED), solar cells and other devices to improve the performance of these devices.
In dye chemistry, it can be used as an important raw material for synthesizing dyes. Because its molecular structure can absorb specific wavelengths of light, through rational design and synthesis, it can produce colorful and stable dyes, which are widely used in textiles, printing and other industries to add rich colors to various fabrics and materials.
In conclusion, 1 - (diethylamino) - 4 - cyanobenzene has indispensable uses in many fields such as medicine, materials, dyes, etc. due to its unique chemical structure, promoting the development and progress of related industries.
What are the physical properties of 1- (difluoromethoxy) -4-nitrobenzene?
1 - (diethylamino) -4 -cyanobenzene, this is an organic compound. Its physical properties are rich and diverse, let me tell them one by one.
Looking at its properties, it usually shows a white to light yellow crystalline powder state under normal conditions, which is easy to observe and handle.
When it comes to the melting point, it is about a certain range. This property is of great significance to its phase transition under specific conditions and is related to many practical application scenarios. The exact value of its melting point is the key indicator of its physical properties. It is an important consideration in the design of production processes and quality control in the fields of chemicals, pharmaceuticals, etc.
In terms of solubility, 1- (diethylamino) -4-cyanobenzene exhibits a unique performance in organic solvents. In common organic solvents such as ethanol and acetone, it has a certain solubility. This property makes it possible to select a suitable solvent for dissolution, extraction, reaction and other steps in related chemical operations, so as to facilitate chemical synthesis and subsequent separation and purification work.
In terms of stability, the substance is usually relatively stable under conventional environmental conditions. In case of high temperature, open flame or strong oxidant, the stability will be challenged, or there may be a chemical reaction. During storage and transportation, special vigilance is required, and corresponding safety regulations must be followed to prevent accidents.
In addition, its density is also a specific value. Although the value seems ordinary, it actually plays an indispensable role in many practical operations involving material mixing and separation, affecting the stratification, flow and other characteristics of the mixture.
In summary, the physical properties of 1- (diethylamino) -4-cyanobenzene are related to each other in terms of properties, melting point, solubility, stability, density, etc., which together determine its application in different fields and potential value, and also provide an important basis for related research and actual production operations.
Is the chemical property of 1- (difluoromethoxy) -4-nitrobenzene stable?
The chemical properties of 1 - (diethylamino) -4 -cyanobenzene are relatively stable. In this substance, the diethylamino group is connected to cyanobenzene, and the two interact structurally, giving the compound specific stability.
From the perspective of chemical bonds, the nitrogen atom in the diethylamino group is covalently connected to the benzene ring, and the lone pair of electrons on the nitrogen atom can form a conjugate system with the benzene ring, which makes the electron cloud distribution more uniform and enhances the stability of the benzene ring. And the alkyl group has a donor electron induction effect, which can provide electrons for the benzene ring and further stabilize the molecular structure.
The carbon-nitrogen triple bond in the cyano group (-CN) is quite stable, and it can also participate in the conjugation system Due to the electron-withdrawing conjugation effect and electron-withdrawing induction effect of the cyanyl group, although the electron cloud density of the benzene ring is reduced, the entire conjugated system is stabilized.
At the same time, the atoms in the molecule reduce the tensile energy of the molecule and improve its stability through a reasonable spatial arrangement. In the usual chemical environment, as long as there are no extreme conditions such as strong oxidants, strong acids, strong bases or high temperatures, the chemical properties of the substance are not easy to change and can maintain a relatively stable state.
What is the preparation method of 1- (difluoromethoxy) -4-nitrobenzene?
The preparation method of 1 - (diethylamino) - 4 - cyanobenzene should follow the following steps.
First, an appropriate amount of starting material should be taken. This starting material needs to be carefully selected to ensure that its purity and quality meet specific standards in order to lay a solid foundation for subsequent reactions. In general, a compound with a specific chemical structure and properties is selected, and this compound can smoothly participate in the reaction and convert to the target product under subsequent reaction conditions.
Next, the starting material should be placed in a suitable reaction vessel. This reaction vessel needs to be carefully selected according to the reaction characteristics, and should have good chemical stability and thermal stability to resist the influence of chemical corrosion and temperature changes that may occur during the reaction. For example, for some reactions that need to be carried out in high temperature or strong acid-base environments, special glass or metal reaction vessels are required.
Then, add an appropriate amount of reaction reagent. The type and dosage of this reaction reagent need to be accurately calculated and prepared according to the chemical reaction mechanism involved. The proportional relationship between reagents has a great impact on the reaction process and product purity. For example, in some catalytic reactions, although the amount of catalyst is small, it plays a key role in the reaction rate and the direction of product formation. In the preparation of 1 - (diethylamino) - 4 - cyanobenzene, the specific reagent combination and dosage are set to promote the chemical reaction of the starting material according to a specific path, and gradually form the target product.
Furthermore, control the reaction conditions. Temperature, pressure, reaction time and other conditions are all important factors affecting the reaction result. Appropriate reaction temperature can speed up the reaction rate and promote the reaction to proceed in a favorable direction. The regulation of pressure is particularly critical in some reactions involving gas participation. And precise control of the reaction time can ensure that the reaction is fully carried out and avoid excessive or insufficient reaction. In the preparation of this compound, through repeated experiments and exploration, the appropriate reaction temperature range, pressure value and reaction time were determined to ensure the high yield and high purity of the product.
After the reaction is completed, the reaction product is separated and purified. Using separation techniques such as extraction, distillation, crystallization, etc., the target product is effectively separated from the reaction mixture, and impurities are removed, and finally pure 1- (diethylamino) -4-cyanobenzene is obtained.
What should be paid attention to when storing and transporting 1- (difluoromethoxy) -4-nitrobenzene?
(1) When storing
1. ** Moisture-proof **: Both are prone to moisture deterioration. (Divinylamino) materials, if attacked by moisture, their structures are easily damaged and their properties are greatly changed; 4-pyridyl naphthalene may cause crystal transformation after moisture, which affects its quality. Therefore, it needs to be placed in a dry place, and desiccants can be prepared next to it, such as lime, anhydrous calcium chloride, etc., to keep the environment dry.
2. ** Avoid light **: Light is the "enemy" of many substances, and (divinylamino) and 4-pyridyl naphthalene are no exception. Under light, (divinylamino) or photochemical reactions can change its chemical properties; 4-pyridylnaphthalene may also decompose due to light. Be sure to store it in a brown bottle, or in a dark place to avoid direct light.
3. ** Temperature is suitable **: either too high or too low temperature is not conducive to the preservation of both. High temperature can cause (divinylamino) volatilization to intensify, 4-pyridylnaphthalene may accelerate decomposition; low temperature may cause some substances to solidify, crystallize, etc., affecting its subsequent use. Usually, the temperature should be controlled in the normal temperature range. If conditions permit, precise temperature control in a specific range is better.
4. ** Isolated storage **: (divinylamino) and 4-pyridyl naphthalene have different chemical properties. In order to prevent mutual contamination and reaction, they need to be stored in isolation. Different batches and specifications should also be separated, and the label should be made, indicating the name, specification, date, etc.
(2) During transportation
1. ** The packaging is strong **: On the road, vibration and collision are unavoidable. (Divinylamino) and 4-pyridyl naphthalene need to be protected by strong packaging. Choose thick, pressure-resistant containers, such as glass bottle coat thick cartons, or use specially customized plastic containers, and fill with foam, cotton and other cushioning materials to prevent damage and leakage.
2. ** Follow the regulations **: When transporting such chemical substances, it is necessary to follow relevant regulations and standards. The transporter must have professional qualifications, and the vehicle must have corresponding identification and protective equipment. The transportation route should be planned in advance to avoid densely populated areas and environmentally sensitive areas in case of serious consequences caused by leakage.
3. ** Real-time monitoring **: During transportation, it is advisable to monitor environmental factors such as temperature and humidity in real time. In case of abnormalities, such as sudden temperature rise, packaging leakage, etc., take timely measures. Equipped with emergency treatment tools and materials, such as adsorbents, neutralizers, etc., so as to respond quickly in case of emergencies.