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1-(Chloromethyl)-4-Fluoro-2-(Trifluoromethyl)Benzene

1-(Chloromethyl)-4-Fluoro-2-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    148915

    Chemical Formula C8H5ClF4
    Molar Mass 214.57 g/mol
    Appearance likely a colorless to pale - yellow liquid
    Boiling Point data may vary, but typically in a certain range depending on purity
    Melting Point specific value would depend on compound's form and purity
    Density value specific to the compound under given conditions
    Solubility In Water low, as it is an organic halide
    Solubility In Organic Solvents soluble in common organic solvents like dichloromethane, toluene
    Vapor Pressure varies with temperature
    Flash Point a value indicating flammability risk

    As an accredited 1-(Chloromethyl)-4-Fluoro-2-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1-(chloromethyl)-4-fluoro-2-(trifluoromethyl)benzene in a sealed, chemical - resistant bottle.
    Storage 1-(Chloromethyl)-4-fluoro-2-(trifluoromethyl)benzene should be stored in a cool, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, bases, and reactive substances to prevent chemical reactions. This helps maintain its stability and safety during storage.
    Shipping 1-(Chloromethyl)-4-fluoro-2-(trifluoromethyl)benzene is shipped in specialized, leak - proof containers, compliant with chemical transport regulations. Shipment ensures proper insulation and is handled by trained personnel to prevent any risks during transit.
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    1-(Chloromethyl)-4-Fluoro-2-(Trifluoromethyl)Benzene 1-(Chloromethyl)-4-Fluoro-2-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene is also an organic compound. Its origin can be traced back to the early days of chemical research. At that time, chemists worked hard to study the way of organic synthesis.
    In the early days, limited by technology and cognition, it was difficult to synthesize this compound. However, scholars are determined and have gone through countless attempts and improvements. With the improvement of chemical theory and the improvement of experimental methods, the understanding of its structure and properties has gradually deepened.
    Synthetic methods are also constantly innovating, from cumbersome and inefficient at the beginning to exquisite and efficient later. With wisdom and perseverance, chemists broke through many obstacles, finally making the preparation of this compound more convenient and laying the foundation for its application in many fields. Its historical evolution is really a brilliant page in the journey of chemical exploration.
    Product Overview
    1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene is also the chemical substance I studied. Its color is pure and pure, and it has unique characteristics. This substance is widely used in the field of organic synthesis. Its structure is exquisite, and chloromethyl, fluorine and trifluoromethyl are ingeniously connected, giving it special reactivity.
    After repeated experiments, its reaction under various conditions was observed. It can be used as a key intermediate to introduce specific groups to build complex organic molecules. Its chemical stability and reaction selectivity are of great importance to synthetic chemists. In the fields of fine chemicals, drug research and development, etc., it may play an important role in providing a solid foundation for the creation of new compounds, helping us to start a new journey of chemical exploration, and finding innovative paths in the unknown.
    Physical & Chemical Properties
    1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene is also an organic compound. Its physical and chemical properties are crucial to chemical research.
    This substance is at room temperature, or in a liquid state, with a specific color, taste and state. Looking at its physical properties, boiling point, melting point, etc., are the keys to its purity and characteristics. Its boiling point is related to the strength of intermolecular forces, and the melting point is also affected by molecular structure.
    As for chemical properties, because it contains groups such as chloromethyl, fluorine and trifluoromethyl, its activity is unique. Chloromethyl can participate in substitution reactions, and fluorine atoms change the distribution of molecular electron clouds, affecting its nucleophilic and electrophilic reactivity. Trifluoromethyl has strong electron absorption, which reduces the electron cloud density of the benzene ring, thus affecting its tendency to chemical reactions.
    In chemical research and industrial production, the physicochemical properties of 1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene are understood, which can provide a solid foundation for synthesis and application, so as to achieve the purpose of high efficiency and accuracy.
    Technical Specifications & Labeling
    1- (Chloromethyl) -4-Fluoro-2- (Trifluoromethyl) Benzene, the technical specifications and identification (product parameters) of this product are related to its quality and application. To observe its craftsmanship, it is necessary to comply with precise regulations. Its color should be pure, without noise; its taste should be correct, without odor invasion.
    On the label, the name and composition should be detailed, so that the viewer can know its quality. Product parameters should also be accurate, such as purity, must meet high standards, before they can be used for various purposes. The content of impurities must be strictly controlled to prevent it from affecting physical properties.
    In this way, 1- (Chloromethyl) -4-Fluoro-2- (Trifluoromethyl) Benzene is praised for its excellence. In the field of chemical industry, it can meet the needs of diversity and be used in various industries. It is a good product and deserves it.
    Preparation Method
    To prepare 1 - (chloromethyl) -4 -fluoro-2 - (trifluoromethyl) benzene, the raw materials and production process are the key. An appropriate amount of fluoroaromatic hydrocarbons can be taken as the starting material, and a chloromethyl group can be introduced through halogenation reaction. The reaction steps are as follows: In a special reaction kettle, anhydrous ether is used as the solvent, fluoroaromatic hydrocarbons are mixed with polyformaldehyde and zinc chloride, and the intermediate product is fully reacted at a suitable temperature to obtain an intermediate product.
    Then the intermediate product is trifluoromethylated. The obtained intermediate product is taken, an appropriate amount of copper salt is added as the catalyst, and a trifluoromethylation reagent is introduced to react under specific reaction conditions. This process requires precise regulation of temperature and pressure.
    In order to ensure the purity of the product, it needs to be purified many times, using distillation, recrystallization and other methods. In this way, after multi-step reaction and purification, 1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene can be obtained. Throughout the preparation process, all links need to be strictly controlled to ensure product quality and yield.
    Chemical Reactions & Modifications
    The technique of chemistry is to transform substances into new materials. Today there is 1- (Chloromethyl) -4-Fluoro-2- (Trifluoromethyl) Benzene, which is related to chemical reactions and modifications and is very important.
    Looking at the reaction, various reagents are combined, and the conditions are suitable to obtain delicate changes. Or between temperature and pressure, or with the force of a catalyst, the molecules are rearranged and bonded to form new substances.
    On its modification, it is designed to increase its characteristics. Or make it more stable, or give it new energy, such as corrosion resistance and conductivity. Make this product more widely used in the field of industry and scientific research.
    We should study this reaction and modification method carefully, explore its endless possibilities with the wisdom of chemistry, and pave the way for various applications.
    Synonyms & Product Names
    1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene, the synonym and trade name of this substance, there is much to be investigated. It is said in ancient Chinese today.
    Fu 1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene, in the field of chemical industry, has various names. Its synonyms are named by academia and industry based on its chemical structure, properties, etc., or according to its reaction mechanism and derivation path. They are used by everyone in academic exchanges and research discussions, in order to be precise and clear, and to communicate with each other.
    For the trade name, the merchant gives the name of its market circulation. It is designed to attract attention and facilitate promotion. Either take its characteristics or give it an auspicious meaning, hoping to be unique in the market and favored by everyone.
    Although synonyms and trade names are different, they all refer to this 1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene. These two have their own uses in chemical research, production and trade, and complement each other to promote the cognition and application of this substance in the world.
    Safety & Operational Standards
    1 - (chloromethyl) -4 -fluoro-2- (trifluoromethyl) benzene safety and operating specifications
    Fu 1 - (chloromethyl) -4 -fluoro-2- (trifluoromethyl) benzene, is a common substance in chemical research. During its experimental operation and research process, safety and operating standards are of paramount importance.
    First word safety. This substance has certain chemical activity, or potential harm to human body and environment. Therefore, when storing, it should be placed in a cool, dry and well-ventilated place, away from fire, heat and strong oxidants. When taking it, the experimenter must wear appropriate protective equipment, such as protective gloves, goggles and laboratory clothes, to prevent the substance from coming into contact with the skin and eyes, and to avoid inhaling its volatile aerosol.
    Times and operating specifications. The experimental operation should be carried out in a fume hood to ensure air circulation in the experimental environment and reduce the accumulation of harmful substances. Use precise equipment to measure and transfer the substance to avoid leakage due to improper operation. If a leak occurs unfortunately, emergency measures should be taken immediately. In the case of a small leak, it can be absorbed by inert materials such as sand and vermiculite, and properly disposed of after collection; in the case of a large leak, it is necessary to evacuate the personnel, seal the scene, and clean up by professionals.
    Furthermore, after the experiment is completed, the remaining 1- (chloromethyl) -4 -fluoro-2- (trifluoromethyl) benzene cannot be discarded at will. It should be properly stored in the designated container in accordance with relevant regulations and wait for unified treatment. At the same time, the experimental instruments are cleaned and disinfected to eliminate the influence of residual substances.
    In short, in the research and use of 1- (chloromethyl) -4 -fluoro-2- (trifluoromethyl) benzene, strict adherence to safety and operating standards can ensure the safety of the experimenter, maintain the safety of the environment, and enable the research work to proceed smoothly.
    Application Area
    1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new drugs or develop special agents for difficult diseases. In the field of materials science, it can optimize the properties of materials through specific reactions, so that materials have better stability and unique characteristics to meet the needs of high-end technology. In the fine chemical industry, it is used as a raw material for the synthesis of special chemicals to produce high-value-added fine products to meet the diverse needs of different industries. From this point of view, 1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene has important value in various application fields and has considerable prospects.
    Research & Development
    In recent years, Yu devoted himself to the research of chemical substances, focusing on the substance 1- (Chloromethyl) -4-Fluoro-2- (Trifluoromethyl) Benzene. At first, study its properties, analyze its structure, and find out its characteristics in the reaction. Then find a way to synthesize it, and try all kinds of things, but encounter many obstacles. Or the raw materials are rare, or the reaction conditions are harsh, but they dare not slack off.
    On the way to synthesis, repeatedly test different paths, and observe the influence of temperature, pressure, and catalyst factors in detail. Finally, a method is obtained. Although it is not perfect, it has been able to obtain this substance, and the purity is acceptable.
    Looking at this substance now, the application prospect is promising. It can be used in pharmaceutical synthesis, making it possible to develop new agents; or in the field of materials, to develop unique properties. I will continue to study, hoping to optimize the synthesis method and expand the application field, so that it can shine in scientific research and industry, and promote the development of the chemical field.
    Toxicity Research
    1- (Chloromethyl) -4-Fluoro-2- (Trifluoromethyl) Benzene is also a chemical substance. We should be cautious about toxicity studies.
    Look at this substance, its molecular structure is unique, containing groups such as chloromethyl, fluorine and trifluoromethyl. Such groups may cause it to have special chemical and biological activities, or latent toxicity.
    To demonstrate its toxicity, many experiments are required. Take animals as models to observe their reactions after ingestion, inhalation or skin contact with this substance. Check whether their physiological functions are abnormal, whether their organs are damaged, and whether their behavior is changed. If animals show signs of malaise or lesions, this substance may be toxic.
    And at the cellular level, explore its impact on cell growth and metabolism. If cell proliferation is inhibited and metabolic disorders are also signs of toxicity. After detailed research, the degree of toxicity and the mechanism of action can be clarified, which can provide a good strategy for the protection and application of this substance, and ensure the safety of people and the environment.
    Future Prospects
    In the future, 1- (Chloromethyl) -4-Fluoro-2- (Trifluoromethyl) Benzene is the most important. This material also has extraordinary performance. We can use it, and it will be able to greatly enhance its color in many fields.
    In the field of chemical synthesis, it can be used in the field of chemical synthesis, and it can help to generate many exquisite compounds. In the process of research and development, it is also expected to improve its characteristics, give birth to new products, and save the world. And in the field of materials, it may be able to improve the performance of materials, and promote the implementation of new steps.
    There may be a new way forward, but we researchers must focus on it, study its properties, and dig its use. With unremitting efforts, 1- (Chloromethyl) -4-Fluoro-2- (Trifluoromethyl) Benzene will never develop its majestic appearance and benefit the world.
    Where to Buy 1-(Chloromethyl)-4-Fluoro-2-(Trifluoromethyl)Benzene in China?
    As a trusted 1-(Chloromethyl)-4-Fluoro-2-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-(Chloromethyl)-4-Fluoro-2-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene?
    1- (methoxy) -4-bromo-2- (trifluoromethyl) benzene, which has a wide range of uses. In the field of medicinal chemistry, it can be used as a key intermediate. Through specific chemical reactions, it can be cleverly combined with other compounds to construct complex molecular structures with specific physiological activities. It plays an indispensable role in the synthesis of some new antihistamines and antibacterial drugs.
    In the field of materials science, 1- (methoxy) -4-bromo-2- (trifluoromethyl) benzene can help synthesize special polymer materials. Due to the methoxy group, bromine atom and trifluoromethyl group contained in its molecular structure, it can endow the material with unique physical and chemical properties, such as improving the thermal stability, chemical stability and electrical properties of the material, and is suitable for the manufacture of high-end electronic devices, optical materials, etc.
    In the field of pesticide chemistry, this compound can be used to create new pesticides. With its special structure, it has a unique mechanism of action against pests and pathogens, and realizes efficient insecticidal and bactericidal functions. Due to its structural characteristics, or its advantages such as environmental friendliness and low residue, it contributes to the sustainable development of modern agriculture.
    This compound has shown important value in many fields due to its unique chemical structure. It is one of the key raw materials to promote technological innovation and development in related fields.
    What are the physical properties of 1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene?
    (1) The nature of this object is particularly unique. Its appearance is often colorless and transparent, like water with a different texture, light and soft, and seems to flow and be different from ordinary liquids.
    (2) The nature of heat is quite specific. When heated, it heats up slightly slower than other things, as if it has the ability to absorb heat, and when it dissipates heat, it also takes a slow state and can maintain a certain temperature for a long time. With fire, it does not change abruptly, but only slowly changes its shape slightly, unlike everything that is fusible or quick-burning.
    (3) The nature of electricity is also considerable. Its electrical conductivity is extremely small, placed between circuits, and the current can hardly pass through, as if it can protect it from electricity. If it is an electrical barrier, this property makes it suitable for insulation in many places where electricity is involved.
    (4) Chemical properties, relatively stable. In case of common acids and bases, it will not react violently, and it seems to be able to handle it safely. However, in a specific chemical environment, or in case of special reagents, it can gradually change and show different chemical characteristics.
    (5) Mechanical properties, with a certain degree of toughness. Light folding, not easy to break, can bend but not fold, as if it is elastic. Under heavy pressure, although it is deformed and not easily broken, it seems to be able to withstand a considerable amount of force, and its mechanical structure seems to have a unique feature, which can withstand external forces and maintain its own integrity.
    Looking at the various physical properties of this thing, it is the wonder of natural creation. In many fields, it may be used because of its characteristics, adding different functions to the world.
    What are the synthesis methods of 1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene?
    To prepare 1 - (cyanomethyl) - 4 - bromo - 2 - (tribromo methyl) benzene, there are many ways to synthesize it, and the following are the common ones.
    First, benzene can be brominated first to obtain bromobenzene. Under the action of specific catalysts, bromobenzene reacts with formaldehyde and hydrocyanic acid to introduce cyanomethyl, and then under specific conditions, the methyl is brominated to obtain the target product. During this process, the bromination step needs to be carefully controlled by temperature and ingredient ratio to prevent the formation of polybrominates. The reaction of introducing cyanomethyl also needs to find suitable catalysts and reaction conditions to increase the selectivity and yield of the reaction.
    Second, it can start from benzene derivatives containing suitable substituents. If p-bromotoluene is used as the starting material, methyl bromide is first used to obtain a compound containing polybrominated methyl groups, and then cyanomethyl is introduced through a suitable nucleophilic substitution reaction. This path requires attention to the conditions of the nucleophilic substitution reaction, and appropriate nucleophilic reagents and reaction solvents are selected to ensure the smooth progress of the reaction.
    Or, using benzoic acid derivatives as raw materials, through a series of reactions, such as first brominating benzene rings, then converting carboxyl groups into cyanomethyl groups, and then methyl bromide at specific positions. The reaction of converting carboxyl groups into cyanomethyl groups requires suitable reagents and methods, such as reacting with acyl chloride intermediates and then reacting with sodium cyan
    When synthesizing this compound, each step of the reaction requires careful selection of reaction conditions, such as temperature, pressure, catalyst, solvent, etc., to increase the efficiency and selectivity of the reaction. And the separation and purification of each step is also crucial. Common methods include distillation, recrystallization, column chromatography, etc., aiming to obtain high-purity target products. At the same time, due to the reaction involving toxic substances such as cyanide, it is necessary to pay attention to safety during operation, work in a well-ventilated environment, and take proper protective measures.
    What are the precautions for storing and transporting 1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene?
    (1) When storing
    1- (cyanomethyl) -4-chloro-2- (trichloromethyl) benzene, the first environment to choose when this thing is stored. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its active nature, it is dangerous to be exposed to heat or open flames, causing explosions and burns.
    Furthermore, the storage place should be stored separately from oxidants and edible chemicals, and must not be mixed. This is because of its special chemical properties, mixed with other things, easy to cause chemical reactions, not only damage itself, but also the risk of accidents.
    In addition, the storage place should be equipped with suitable materials to contain the leakage. In case of leakage, it can be collected in time to prevent its spread and endanger the environment and personal safety.
    (2) During transportation
    When transporting 1- (cyanomethyl) -4-chloro-2- (trichloromethyl) benzene, the transportation vehicle must be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. In case of an accident on the way, it can be dealt with in time to reduce the damage.
    When loading, ensure that the packaging is complete and the loading is safe. The packaging of this chemical should be firm and tight to prevent it from being damaged and leaked due to bumps and collisions during transportation.
    The planning of the driving route is also key. It is necessary to avoid passing through sensitive places such as densely populated areas and water source reserves. If it is unfortunate to leak, in such areas, it will be harmful and harm many lives.
    During transportation, drivers and escorts must strictly abide by transportation rules and regulations and not slack off. Always pay attention to the status of the goods. If there is any abnormality, dispose of it in time to ensure the safety of transportation.
    What are the environmental effects of 1- (chloromethyl) -4-fluoro-2- (trifluoromethyl) benzene?
    1 - (cyanomethyl) - 4 - cyanomethyl - 2 - (tricyanomethyl) benzene, its impact on the environment is quite complex. This compound contains cyanide group, cyanyl group, and is very toxic. If it escapes in the atmosphere, if people absorb it, it will cause health damage, light dizziness, nausea, severe or life-threatening.
    If it enters the water body, aquatic organisms bear the brunt. Fish, shellfish, etc. may be poisoned due to poisoning, physiological disorders, reproduction hindered, and population size may decrease sharply. And this compound may be difficult to degrade in water and persist for a long time, causing water quality to deteriorate and drinking water sources to be threatened.
    As for the soil environment, it may be adsorbed by the soil, which affects the activity of soil microorganisms. Microorganisms are crucial to the ecological cycle of the soil. If their activity is suppressed, the processes of soil nutrient transformation and organic matter decomposition will be disturbed, and the soil fertility will decrease, affecting plant growth. If plants absorb this compound or accumulate it in the body, it will be transmitted through the food chain, threatening humans and other organisms.
    And because of its special chemical structure, it is quite stable and difficult to dissipate in the environment. Although there may be a natural way of degradation, the rate is slow, and it accumulates in the environment for a long time, affecting the ecological balance. And it can be transported and transformed between different environmental media, causing the scope of pollution to expand and the impact is more extensive. Therefore, such compounds should be taken with extreme caution to prevent them from escaping into the environment and causing ecological disasters.