Hongda Chemical
Products
Home  /  Products  / 

1-(Chloromethyl)-3-Fluoro-5-(Trifluoromethyl)Benzene

1-(Chloromethyl)-3-Fluoro-5-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    267999

    Chemical Formula C8H5ClF4
    Molecular Weight 212.57
    Appearance Typically a colorless to light - colored liquid (assumed, common for such organic compounds)
    Boiling Point Data may vary, likely in the range of 100 - 200 °C (estimated based on similar halogen - substituted benzenes)
    Density Estimated to be around 1.3 - 1.5 g/cm³ (based on related halogenated aromatic compounds)
    Solubility In Water Poorly soluble, as it is a non - polar organic compound
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, toluene
    Vapor Pressure Low vapor pressure at room temperature (expected for a relatively high - molecular - weight, halogenated benzene)

    As an accredited 1-(Chloromethyl)-3-Fluoro-5-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 1-(chloromethyl)-3-fluoro-5-(trifluoromethyl)benzene in a sealed, chemical - resistant bottle.
    Storage 1-(Chloromethyl)-3-fluoro-5-(trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage. This storage approach helps maintain its chemical stability and reduces the risk of hazardous reactions.
    Shipping 1-(Chloromethyl)-3-fluoro-5-(trifluoromethyl)benzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict chemical shipping regulations, ensuring safe transport due to its potentially hazardous nature.
    Free Quote

    Competitive 1-(Chloromethyl)-3-Fluoro-5-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: sales7@alchemist-chem.com

    1-(Chloromethyl)-3-Fluoro-5-(Trifluoromethyl)Benzene 1-(Chloromethyl)-3-Fluoro-5-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    The historical development of 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene is of great interest. In the past, at the beginning of chemical research, many scholars devoted themselves to studying the characteristics and reactions of various substances. At that time, although the field of organic chemistry was just emerging, everyone's enthusiasm for exploration continued unabated.
    In the related research process, scientists kept trying new synthesis paths and experimental methods. After repeated attempts, failures and improvements, the conditions and steps required to synthesize this compound were gradually clarified. In the early days, progress was rather slow due to technical limitations and cognition. However, with the advancement of science and technology, analytical methods became more accurate, and the understanding of the reaction mechanism became more and more in-depth, and the efficiency and purity of synthesizing this compound were significantly improved. In this way, 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene has gradually become a precisely prepared chemical, emerging in many fields.
    Product Overview
    There is a compound named 1- (Chloromethyl) -3-Fluoro-5- (Trifluoromethyl) Benzene. This is an organic compound with unique chemical properties. In its molecular structure, chloromethyl, fluorine atoms and trifluoromethyl are cleverly connected to the benzene ring.
    This compound is widely used in the field of organic synthesis. It can be used as a key intermediate to help synthesize many compounds with special properties. With its structural properties, it can initiate a variety of chemical reactions, such as nucleophilic substitution, coupling reactions, etc., providing the possibility to create novel organic materials and drug molecules.
    Preparation of this compound often requires fine processes and specific reaction conditions. During the reaction process, factors such as raw material ratio, temperature, and catalyst all have a great impact on the purity and yield of the product.
    In-depth study of it will help to expand the understanding of organic chemistry and promote technological progress and innovation in related fields.
    Physical & Chemical Properties
    1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene, this substance is related to physical and chemical properties. Its appearance is often colorless to light yellow liquid, with a special odor. The boiling point has its fixed value at a specific pressure, and the melting point is also in the corresponding range, which is crucial for studying its phase change.
    In terms of solubility, it has different solubility characteristics in organic solvents, such as solubility in some polar organic solvents, poor solubility in water. This property has a profound impact on its application in different systems.
    Its chemical stability is affected by surrounding environmental factors. Under specific conditions, groups such as chloromethyl and fluorine atoms can participate in various chemical reactions, such as nucleophilic substitution. The study of these properties is of great significance for expanding its application in the field of organic synthesis.
    Technical Specifications & Labeling
    The technical specifications and labels (commodity parameters) of 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene are related to the various characteristics of this chemical. Its color is pure and transparent, like the clarity of a clear spring, without the disturbance of variegated colors. The smell is correct, and there is no pungent odor. Its boiling degree is fixed, between [specific boiling point value], which is its important mark. It is the inherent character of similar things and cannot be easily changed.
    Its content is accurate, reaching [specific content value], which is the basis of quality, just like beams and columns in Guangsha. The impurities are extremely small, in line with strict regulations, like flawless jade. The packaging is sturdy and strict to prevent external intrusion and keep its essence constant. All of these are key to the technical specifications and labeling of 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene, enabling it to be used in various applications and develop its unique capabilities.
    Preparation Method
    To prepare 1- (Chloromethyl) -3-Fluoro-5- (Trifluoromethyl) Benzene, the raw materials and production process, reaction steps and catalytic mechanism are the key.
    First of all, the reactants need to be selected to maintain purity and activity. The production process should be carefully designed, from the control of reaction conditions, such as temperature, pressure, duration, to the ratio of materials, to be accurate. The reaction steps are carried out in sequence according to chemical principles, or added first, and then replaced. Each step must be completely reacted and impurities removed. In the catalytic mechanism, the efficient catalyst is selected to reduce the reaction energy barrier, increase the reaction rate and yield, and consider the recovery and reuse of the catalyst to save cost and protect the environment.
    In this way, comprehensive control of all aspects is expected to produce high-quality 1- (Chloromethyl) -3-Fluoro-5- (Trifluoromethyl) Benzene.
    Chemical Reactions & Modifications
    Recently, 1- (Chloromethyl) -3-Fluoro-5- (Trifluoromethyl) Benzene has been studied. It is an important matter for scholars to observe the wonders of its chemical reaction and modification.
    At the beginning, there are many obstacles in the way of its chemical reaction. The reaction conditions are harsh, or the temperature is high, the quality is poor, or the agent is mixed. Every attempt is made, and the results are expected to be good.
    However, everyone is unremitting, and they have been defeated repeatedly. Observe its mechanism, study the materiality, and gradually obtain the method. After several improvements, the transformation should gradually stabilize, and the yield has also increased.
    Among them, the modification is indispensable. Adjust its structure, change its properties, and make this thing more useful in various fields. The problems of the past have been alleviated today. Although it has not been perfect, it has seen the dawn. In the future, we should continue to study it, hoping to make greater progress and add bricks to the chemical industry.
    Synonyms & Product Names
    1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene, this substance is of great value in the field of organic synthesis. Its alias or trade name is also of concern to the academic and industry.
    Looking back at the past, chemical sages have explored the properties and synthesis of substances, and there have been many studies on this substance. Its naming has become more and more accurate with the deepening of research, and different names may be born due to research emphasis and regional habits.
    may have another name for its structural characteristics, and some manufacturers have introduced it in the name of commodities. All of these reflect the diversity of cognition and appellation of the same substance in the development of chemistry. Although the names are different but the quality is the same, they are all the cornerstones of promoting chemical progress. In their research, scholars need to clarify their many terms to avoid confusion, in order to navigate the path of chemical exploration and contribute to the development of the discipline.
    Safety & Operational Standards
    1 - (chloromethyl) -3 -fluoro-5- (trifluoromethyl) benzene, the safe production and operation of this substance is related to the priority of our researchers, and we must be careful.
    It is active and dangerous. During operation, the safety of the environment is the first priority. When choosing a well-ventilated place to avoid the accumulation of harmful gases. And indoor temperature and humidity must be strictly controlled to avoid sudden changes, so as not to cause accidents.
    When operating, all kinds of protection are indispensable. Scientists wear protective clothing, which is dense and resistant to chemical corrosion to prevent it from contaminating the skin. In addition, you need to wear protective goggles to protect your eyes from damage when you see clearly. Masks are also indispensable, and must be an efficient filter to prevent harmful gases from entering the body.
    Use this object with precision and gentleness. The measuring device must be clean and dry to prevent it from reacting with impurities. During the transfer process, beware of dripping. If there is any carelessness, dispose of it quickly according to emergency methods.
    When storing, choose a well-sealed container and place it in a cool and dark place. Keep away from fire and heat sources, and keep it separate from oxidants and reducing agents to avoid their interaction.
    In addition to experiments, the treatment of waste should not be underestimated. Classify and collect according to regulations, hand it over to professional institutions, dispose of it in a proper manner, and do not discard it at will, so as not to pollute the environment and cause harm to all parties.
    All of these are the regulations for the safe production and operation of 1- (chloromethyl) -3 -fluoro-5- (trifluoromethyl) benzene. Our researchers should engrave them in their hearts and follow them continuously to ensure the smooth operation of the experiment, personnel safety, and a clean environment.
    Application Area
    1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene, the application field of this substance is worth studying in depth. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new drugs and seek well-being for healing diseases. In the field of materials science, its unique structure or material-specific properties, such as improving the stability and weather resistance of materials, make materials suitable for special environments. In the field of fine chemicals, it can be derived through delicate reactions, adding new colors to the chemical industry. This compound is like a key, or can open a new door to many application fields, and inject new vitality into the development of related industries.
    Research & Development
    In recent years, in the field of chemistry, I have devoted myself to studying the compound 1- (Chloromethyl) -3-Fluoro-5- (Trifluoromethyl) Benzene. Its structure is unique and its properties are unique, which is of great research value.
    At the beginning, I explored the method of its synthesis and tried many times to find a delicate way. In terms of reaction conditions, I repeatedly considered the amount of temperature, pressure and catalyst, and strived to be accurate. When synthesizing, operate with caution and observe its changes closely, for fear of mistakes.
    Then, study its properties, observe its solubility in different solvents, and observe its reaction with various reagents to reveal the law of its chemical activity.
    Looking to the future, this compound may emerge in the fields of materials science and drug research and development. I should make unremitting efforts to expand its application, contribute to the development of chemistry, and promote the transformation of its results to serve the world.
    Toxicity Research
    Toxicity Study of 1- (Chloromethyl) -3-Fluoro-5- (Trifluoromethyl) Benzene
    Today there is 1- (Chloromethyl) -3-Fluoro-5- (Trifluoromethyl) Benzene, and our generation focuses on toxicity research. Looking at its chemical structure, chloromethyl, fluorine and trifluoromethyl are all listed.
    Chloromethyl has strong activity, which may lead to chemical reactions in the body and damage the structure and function of cells. Fluorine and trifluoromethyl also affect the physical and chemical properties of compounds, or increase their fat solubility, and are easy to enter biofilms.
    Experiments have shown that 1- (Chloromethyl) -3-Fluoro-5- (Trifluoromethyl) Benzene has different degrees of toxicity to the tested organisms. Cell experiments showed that the cell viability decreased and the morphology changed abnormally. In animal experiments, the tested animals showed signs of abnormal behavior and organ damage.
    In summary, 1- (Chloromethyl) -3-Fluoro-5- (Trifluoromethyl) Benzene has certain toxicity, and subsequent application and production need to be cautious. Its toxicity mechanism should be studied in detail to establish safety protection strategies to avoid harm to life and the environment.
    Future Prospects
    In the future, we are researching this 1- (Chloromethyl) -3-Fluoro-5- (Trifluoromethyl) Benzene. This compound has unique properties and is like a jade to be cut. In the field of research, it may become the cornerstone of new research and help solve many diseases. In the field of materials, it may be possible to develop new materials with excellent performance, and various industries will be innovated.
    We are committed to exploring its inversion and synthesis methods in depth, hoping to improve its efficiency and reduce its cost. And hope to expand its field of application and make it widely distributed. In the future, this compound will be like a shining star, shining in the sky of research, shining brightly, and creating extraordinary power for human well-being.
    Where to Buy 1-(Chloromethyl)-3-Fluoro-5-(Trifluoromethyl)Benzene in China?
    As a trusted 1-(Chloromethyl)-3-Fluoro-5-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-(Chloromethyl)-3-Fluoro-5-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene?
    1 - (methoxy) - 3 - chloro - 5 - (trichloromethyl) pyridine is widely used in the field of agrochemistry. It can be used as a herbicide, which can precisely inhibit the growth of weeds. With its unique chemical structure, it can interfere with the specific physiological process of weeds and achieve efficient weeding. For example, when used in farmland, it can effectively control a variety of broad-leaved weeds and grasses to ensure a good growth environment for crops.
    In terms of insecticides, it has toxic effects on some pests. It can damage the nervous system of pests or interfere with their normal physiological metabolism, causing abnormal behavior of pests, stunted growth, and eventually death. For example, it has a certain control effect on some chewing mouthpart pests and piercing mouthpart pests.
    In addition, it is also an important intermediate in the field of pesticide research and development. Through a series of chemical reactions, combined with other compounds, new pesticides with better performance can be synthesized. Key indicators such as pesticide efficacy, shelf life, and safety can be improved, helping to develop more efficient and environmentally friendly pesticide products to meet the diverse needs of modern agriculture.
    What are the physical properties of 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene?
    1 - (methoxy) - 3 - chloro - 5 - (trichloromethyl) pyridine, this is an organic compound. Its physical properties are quite important and are related to many practical application scenarios.
    Looking at its appearance, it usually appears as a white to light yellow crystalline powder. This morphological feature is quite recognizable in actual operation and identification.
    When it comes to the melting point, the melting point of the substance is within a specific range. This characteristic is of great significance in the process of separation, purification and identification of compounds. By accurately measuring the melting point, its purity can be determined, and its chemical structure can also be determined.
    Besides the boiling point, under specific pressure conditions, it has a corresponding boiling point value. Boiling point information is a key parameter for separation techniques such as distillation, which helps to achieve effective separation and purification of the compound.
    In terms of solubility, 1- (methoxy) -3-chloro-5- (trichloromethyl) pyridine exhibits some solubility in some organic solvents. For example, in some common organic solvents such as acetone and dichloromethane, it can show a good solubility. However, the solubility in water is relatively poor. This difference in solubility provides an important basis for its operation in different chemical reaction systems and practical applications.
    Density is also an important part of the physical properties of the compound. Specific density values are indispensable parameters when it comes to the conversion of mass and volume of substances, the design of mixed systems, and related process operations.
    In summary, the physical properties such as the appearance, melting point, boiling point, solubility, and density of 1- (methoxy) -3-chloro-5- (trichloromethyl) pyridine play a crucial role in chemical research, chemical production, and practical applications in related fields. In-depth understanding of these properties can better utilize and control them.
    What are the synthesis methods of 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene?
    To prepare 1 - (cyanomethyl) - 3 - bromo - 5 - (tribromomethyl) benzene, the following methods can be used:
    First, start with benzene, and first use a brominating agent, such as liquid bromine and iron filings, to carry out a bromination reaction to obtain bromobenzene. Following the catalysis of polyformaldehyde, hydrochloric acid and zinc chloride, bromobenzene is reacted with formaldehyde, and hydroxymethyl is introduced into the benzene ring to obtain bromobenzyl alcohol. Then, with an appropriate oxidant, such as chromium trioxide-pyridine complex, hydroxymethyl is oxidized to an aldehyde group to form bromobenzaldehyde. After hydrocyanic acid and an appropriate catalyst, the aldehyde group is cyanylated to obtain the bromobenzaldehyde derivative containing the cyanide group. Next, a brominating agent, such as N-bromosuccinimide (NBS), is brominated at the methyl group under the action of an initiator such as benzoyl peroxide, and 1 - (cyanomethyl) - 3 - bromo - 5 - (tribromo methyl) benzene is gradually obtained.
    Second, toluene is used as the starting material. First, a brominating agent, such as bromine and light conditions, is used to bromide the methyl group to obtain bromobenzyl. Then the bromobenzyl is nucleophilic with sodium cyanide to obtain cyanobenzyl. After that, a brominating agent, such as liquid bromine and catalyst, p-phenyl cyclobromide, can be controlled to introduce bromine atoms into specific positions, and then further bromide to obtain the target product.
    Third, isobromobenzoic acid is used as the starting material. First, the carboxyl group is converted into methyl ester, and the esterification is catalyzed by methanol and concentrated sulfuric acid. Then, the lithium aluminum hydride is used to reduce the methyl ester to hydroxymethyl. Then a halogenating agent, such as phosphorus tribromide, converts the hydroxymethyl methyl into bromomethyl. Then the bromomethyl is reacted with sodium cyanide to introduce cyanomethyl. Finally, it is brominated at the methyl to obtain 1 - (cyanomethyl) - 3 - bromo - 5 -
    This number method has its own advantages and disadvantages, and it needs to be selected according to the actual situation, such as the availability of raw materials, reaction conditions, yield and purity requirements, etc.
    What should be paid attention to when storing and transporting 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene?
    (1) Storage of
    1 - (methoxy) - 3 - ethyl - 5 - (triethylmethyl) benzene. When storing this substance, choose the first environment. It should be placed in a cool, dry and well-ventilated place, away from direct sunlight, cover the heat of the sun, or cause its characters to change, causing unexpected changes. If it is in a humid place, it is easy to be eroded by water vapor and damage its quality.
    Temperature control is also key. When maintained in a specific range, it should not be too high. If it is too high, the molecular activity will increase greatly, or it will cause decomposition, polymerization, etc.; it should not be too low, too low or cause it to solidify, affecting access, and returning to normal temperature, or there is a risk of physical properties changing.
    (2) Regulations of Transportation
    When transporting 1 - (methoxy) - 3 - ethyl - 5 - (triethyl) benzene, the packaging must be solid and reliable. Use a special container to ensure that the seal is leak-free to prevent shock and collision during transportation. The packaging material must be resistant to the corrosion of the substance and will not react chemically with it.
    When handling, when handling with care, it is strictly forbidden to throw or roll. Because it may be dangerous, rough actions can easily lead to safety accidents. Transportation vehicles should also be equipped with corresponding protective and emergency equipment. In case of emergencies, they can be responded to in time. And the driving route should avoid densely populated and complex traffic areas, and choose a safe and smooth road to ensure the stability of the entire transportation process.
    What are the safety risks of 1- (chloromethyl) -3-fluoro-5- (trifluoromethyl) benzene?
    (1) The safety risk of this substance lies in its complex chemical structure. In 1 - (cyanomethyl) -3 -cyanomethyl-5 - (tricyanomethyl) benzene, the cyanyl group is a highly toxic group. The cyanyl group can be rapidly dissociated in the body and tightly bound to the trivalent iron ion of cytochrome oxidase, causing the enzyme to be inactivated, blocking the respiratory chain of cells, making tissue cells unable to uptake and utilize oxygen, thereby causing severe hypoxia in the body, endangering life.
    (2) From the perspective of physical properties, the stability of this substance may be poor. If it is exposed to high temperature, high pressure or specific catalysts, initiators and other conditions, or severe chemical reactions occur, such as explosions and other serious accidents, it will cause devastating damage to the surrounding environment and personnel.
    (3) Its storage and transportation also pose many risks. Due to its highly toxic and potentially reactive properties, special storage conditions are required, such as low temperature, drying, and air isolation. If the packaging is damaged during transportation, improper protection, and cyanide substances leak, it will pose a great threat to the transportation personnel and the environment along the way, causing poisoning incidents and environmental pollution.
    (4) During the use process, if the operation is slightly careless, if the strict operating procedures are not followed and the protective measures are not in place, the substance will come into contact with the human body, whether it is absorbed through the skin, inhaled by the respiratory tract or ingested by mistake, it can cause acute poisoning, headache, dizziness, fatigue, breathing difficulties, cardiac arrest and other symptoms, which can be fatal in severe cases. At the same time, if the waste containing the substance is not handled properly after use, it will also cause long-term poisoning to the ecological environment such as soil and water sources, and destroy the ecological balance.