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1-(Chloromethyl)-2,4-Bis(Trifluoromethyl)Benzene

1-(Chloromethyl)-2,4-Bis(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    581612

    Chemical Formula C9H5ClF6
    Molar Mass 276.58 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point 168 - 170 °C
    Density 1.447 g/cm³
    Solubility In Water Insoluble
    Flash Point 63 °C
    Refractive Index 1.396

    As an accredited 1-(Chloromethyl)-2,4-Bis(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 1-(chloromethyl)-2,4-bis(trifluoromethyl)benzene in sealed chemical - grade bottle.
    Storage 1-(Chloromethyl)-2,4-bis(trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials, as it may react with some substances. Store it separately from oxidizing agents and incompatible chemicals to prevent hazardous reactions.
    Shipping 1-(Chloromethyl)-2,4-bis(trifluoromethyl)benzene is shipped in accordance with strict chemical transport regulations. It's carefully packaged in corrosion - resistant containers to prevent leakage during transit to ensure safety.
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    1-(Chloromethyl)-2,4-Bis(Trifluoromethyl)Benzene 1-(Chloromethyl)-2,4-Bis(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene, its substance, is also gradually emerging in the field of chemical industry. At the beginning, scholars studied and strived to make methods. At that time, the technology was not refined, and it was difficult to produce and the amount was small.
    However, the years have changed, and the researchers have been unremitting to explore better techniques. The choice of materials and the adjustment of steps have all made progress. In the past, making this thing often encountered difficulties, but now it can be more easily obtained.
    Since its appearance, it has gradually become useful in various industries. The research of medicine may use its properties to help create new drugs; the production of materials also depends on its quality to explore new fields. From this perspective, the development of 1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene has gradually begun, and the prospect is promising, which will add luster to the history of chemical industry in the future.
    Product Overview
    1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene, an organic compound. It may be a colorless liquid with a special odor. This compound is widely used in the field of organic synthesis.
    In its molecular structure, chloromethyl is connected to bis (trifluoromethyl) phenyl, and its unique structure gives it special chemical properties. Because of its fluorine atom, it has high stability and chemical inertness.
    In organic synthesis reactions, it is often used as a key intermediate. Through specific reaction pathways, other functional groups can be introduced to build a multi-component organic molecular structure, which has potential application value in pharmaceutical chemistry, materials science and other fields, providing an important material basis for the study of organic synthetic chemistry.
    Physical & Chemical Properties
    1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene, its physical and chemical properties are quite unique. Looking at its shape, it may be a colorless to light yellow liquid at room temperature, with a special odor. Its boiling point and melting point are affected by the presence of chloromethyl and ditrifluoromethyl in the molecular structure. The reactivity of chloromethyl makes this substance chemically active and easy to participate in nucleophilic substitution reactions. Trifluoromethyl has strong electron absorption and affects molecular polarity, resulting in its solubility in organic solvents. In terms of density, it may have specific values due to the accumulation of atomic types and structures. And because it contains fluorine, chlorine and other elements, its stability also has corresponding characteristics. In chemical reactions and practical applications, these physicochemical properties determine its use and behavior.
    Technical Specifications & Labeling
    Today there is a product called 1- (Chloromethyl) -2,4-Bis (Trifluoromethyl) Benzene. Its technical specifications and identification (commodity parameters) are crucial to the quality and use of this product.
    On its technical specifications, it is necessary to clarify the method of synthesis, the raw materials must be pure, and the steps must be careful, such as temperature control, speed regulation, etc., in order to obtain high-quality products. The identification (commodity parameters) details the properties of this product, such as color, taste, state, and its content, purity and other data for people to identify.
    For those who study this product, it is essential to adhere to the technical specifications and accurately establish the identification (product parameters) in order to make this product fit the needs and be used in the local area, and live up to the original intention and expectations of the research.
    Preparation Method
    To prepare 1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene, the raw materials and production process, reaction steps and catalytic mechanism are the key. First, an appropriate amount of 2,4-bis (trifluoromethyl) toluene is taken as the starting material. In a suitable reaction vessel, a specific halogenating agent such as N-chlorosuccinimide (NCS) is used to initiate a free radical substitution reaction under the action of an initiator such as azobisisobutyronitrile (AIBN). This reaction requires strict temperature control, about 60-80 degrees Celsius, continuous stirring to make the reaction uniform and sufficient. After the reaction is completed, the product is purified by distillation, extraction and other subsequent steps. In this way, by means of exquisite raw material selection, rigorous reaction steps and rational catalytic mechanism, 1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene can be obtained.
    Chemical Reactions & Modifications
    There is now a substance named 1- (Chloromethyl) -2,4-Bis (Trifluoromethyl) Benzene. In the field of chemistry, it is important to explore its reaction and modification.
    Looking at this compound, its structure is unique, chloromethyl is connected to the benzene ring containing trifluoromethyl. Its chemical properties are determined by the group. To find a way to modify it, the reason for its reaction must be clarified.
    In the reaction, chloromethyl has a high activity and can lead to nucleophilic substitution. With appropriate reagents, or can change its group, it can cause changes in molecular function. And trifluoromethyl has strong electron absorption, which affects the electron cloud distribution of benzene ring and also plays a role in the reaction selectivity.
    After experiments and analysis, the reaction conditions may be optimized to improve the yield and improve the purity of the product. The way of modification, or the introduction of new functional groups, endows it with special properties, such as enhancing stability and changing solubility, and is used in materials, medicine and other fields. The road of chemical exploration is long, and unremitting research can be used to obtain the wonderful reaction and modification of this compound.
    Synonyms & Product Names
    1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene, this substance is of great significance in our chemical research. The study of its aliases and trade names is actually an important matter for scientific research.
    In the past, we searched in ancient books, and we knew that there were many names. Or according to its structural characteristics, it was called by a certain name; or due to differences in preparation methods, it was another name. And different regions and schools also have similarities and differences in the title of this object.
    Today, trade names also change with market and industry habits. However, whether it is an alias or a trade name, it is convenient for us to identify and communicate this object. Only by accurately grasping the same nouns and trade names can we be able to move freely in the fields of chemical research and industrial production, and convey information without error, thus avoiding the risk of confusion.
    Safety & Operational Standards
    1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene is also a chemical product. It is related to safety and operating standards and cannot be ignored.
    When taking it, clean your hands and face, wear protective clothing, gloves and goggles to guard against its damage. The place to be handled must be well ventilated, and there is no danger of open flames, which may cover this thing or pose a risk of explosion.
    The method of storage also needs to be strict. It should be placed in a cool and dry place, away from heat sources and oxidants, to prevent deterioration and risk. And it needs to be clearly marked, so that people can know its properties at a glance.
    If you accidentally touch the skin, quickly rinse it with a lot of water, then wash it with soap; if it enters the eyes, you need to rinse it with water immediately, and seek medical treatment urgently. In case of leakage, cut off the fire source first, evacuate everyone, and then cover it with sand, etc., collect it carefully, and dispose of it according to regulations, so as not to pollute the environment.
    Those who use this product should be familiar with safety and operation regulations, and be meticulous to ensure safety. This is the way of chemical industry, and it is also the responsibility.
    Application Area
    1 - (chloromethyl) -2,4 -bis (trifluoromethyl) benzene, the application field of this substance is quite wide. In the field of medicinal chemistry, it can be a key intermediate to help create new special drugs, and play a unique role in specific diseases. In material science, it can participate in the synthesis of high-performance materials, giving materials such as excellent weather resistance and corrosion resistance. In the field of fine chemistry, it can be used as raw materials to prepare many high-value-added fine chemicals, which are used in electronics, daily chemicals and other industries. Its unique chemical structure has made researchers in various fields compete to explore, expand its application boundaries, and inject new impetus into the development of many industries. It has broad prospects and will surely emerge in more fields in the future and play an important role.
    Research & Development
    In recent years, I have been involved in chemical substances, especially 1- (Chloromethyl) -2,4-Bis (Trifluoromethyl) Benzene. Its properties are different, and it often shows a unique effect in various reactions.
    The initial study of this substance, the preparation method, is quite laborious. All kinds of raw materials, the ratio needs to be fine, and the temperature and time of the reaction must also be carefully observed. After repeated tests, a good method can be obtained, and the yield gradually increases.
    As for its application, the prospect is broad. In the synthesis of medicine, it can be used as a key intermediate and a new agent. In the field of materials, it can also be used or can be used to add new properties.
    Our generation should study diligently, hoping to explore its secrets more, promote the development of this product, and contribute to the progress of chemistry to benefit the world.
    Toxicity Research
    The industry of chemical industry is related to people's livelihood, but the investigation of poisons in the process cannot be ignored. Today, there is a thing called 1- (Chloromethyl) -2,4-Bis (Trifluoromethyl) Benzene, and the study of its toxicity is quite important.
    Observe this thing, in the experimental place, and explore it in detail. Take all kinds of creatures as an experiment, and observe that they are affected by this substance. Or see its vitality is sluggish, or feel its physiological violation. Its damage to the body, or involves the viscera, or meridians.
    From this perspective, 1- (Chloromethyl) -2,4-Bis (Trifluoromethyl) Benzene is significantly toxic, and it is hidden in the environment and human body. Researchers should do their best to study its nature, in order to find ways to avoid harm, to protect the well-being of all beings, and to protect the tranquility of the environment. In the future, the chemical industry can not only make profits, but also eliminate problems. This is the wish of our generation.
    Future Prospects
    I have tried to study chemical products. Looking at this product of 1- (Chloromethyl) -2,4-Bis (Trifluoromethyl) Benzene today, I feel that its future is quite promising. The nature of this product may be of great use in the creation of new materials and medical techniques.
    Looking at today, the technology of chemical industry is new day by day, and all kinds of new products are emerging one after another. This 1- (Chloromethyl) -2,4-Bis (Trifluoromethyl) Benzene, if it is well researched, may be able to open up new paths. Together with new materials, it can help to develop specific qualities, additive properties, and make it more widely used. In medicine, or as the foundation for the creation of good medicines, it can solve the suffering of all diseases.
    Although there may be thorns in the road ahead, I believe that with time and diligent exploration, I will be able to demonstrate its power, be used by the world, develop the grand future, and create infinite well-being.
    Where to Buy 1-(Chloromethyl)-2,4-Bis(Trifluoromethyl)Benzene in China?
    As a trusted 1-(Chloromethyl)-2,4-Bis(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-(Chloromethyl)-2,4-Bis(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 1- (Chloromethyl) -2,4-Bis (Trifluoromethyl) Benzene?
    1 - (chloromethyl) - 2,4 - bis (trifluoromethyl) benzene, this substance has a wide range of uses. In the field of organic synthesis, its position is crucial. Due to its unique properties of chloromethyl and trifluoromethyl in its structure, it can be used as a key intermediate to participate in the construction of multiple complex organic compounds.
    In the field of materials science, it also shows great value. By incorporating it into polymer materials through specific chemical reactions, the properties of materials can be effectively improved. Such as improving the chemical stability of materials, making them more resistant to chemical attack; enhancing their thermal stability, and maintaining good performance in high temperature environments.
    In the field of medicinal chemistry, it also plays an important role. Due to its special structure, it can participate in the design and synthesis of drug molecules, or it can endow drugs with unique biological activities and pharmacological properties, providing new opportunities for the development of new drugs.
    Furthermore, in the field of pesticide chemistry, pesticides synthesized from it may have the characteristics of high efficiency, low toxicity, and environmental friendliness, making great contributions to agricultural pest control. Its special structure may help to enhance the targeting and effect of pesticides on pests, while reducing the adverse effects on the environment and non-target organisms. In short, 1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene has important uses in many fields, providing strong support for the development of many fields.
    What are the physical properties of 1- (Chloromethyl) -2,4-Bis (Trifluoromethyl) Benzene
    1 - (chloromethyl) - 2,4 - bis (trifluoromethyl) benzene, is a kind of organic compound. Its physical properties are particularly important, and it is related to its application and treatment.
    When it comes to appearance, this compound is usually a colorless to light yellow liquid, with a clear texture and no impurities visible to the naked eye. Looking at it, it is like a quiet liquid, but it contains chemical vitality.
    Its smell has a specific aromatic aroma. Although it is not pungent, it is also a significant characterization of its physical properties, and its characteristics can be recognized by smelling.
    As for the boiling point, it is about a specific temperature range. The critical temperature at which the compound changes from liquid to gas state is covered by the boiling point. The boiling point of 1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene allows us to know under what temperature conditions the phase change will occur. This is a key parameter in chemical operations such as distillation and separation.
    Melting point is also an important physical property. The melting point of this compound determines the low temperature at which it will solidify from liquid to solid. Knowing the melting point helps to control the temperature conditions during storage and transportation to maintain its suitable physical state.
    In terms of density, each unit volume has a certain amount of mass. This density characteristic affects its distribution and behavior in the mixing system. It is of great significance in chemical synthesis and industrial production for phase separation and mixing.
    In terms of solubility, it can be soluble in a variety of organic solvents, such as common ethanol, ether, etc. This solubility provides the possibility for its application as a reactant or solvent in chemical reactions, and also determines its existence form and reactivity in a specific chemical environment.
    In addition, its volatility also has characteristics. At room temperature and pressure, there is a certain degree of volatilization. This property affects its concentration changes in storage and use environments, and is related to the safety of operation and the purity of the product.
    These various physical properties are interrelated and together outline the physical properties of 1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene, laying the foundation for its research, development and application in the field of chemistry.
    What are the synthesis methods of 1- (Chloromethyl) -2,4-Bis (Trifluoromethyl) Benzene
    There are several methods for synthesizing 1 - (chloromethyl) - 2,4 - bis (trifluoromethyl) benzene as follows.
    First, 2,4 - bis (trifluoromethyl) benzoic acid is used as the starting material. First, 2,4 - bis (trifluoromethyl) benzoic acid is co-heated with dichlorosulfoxide. In this step, the carboxyl group is converted into an acyl chloride group to obtain 2,4 - bis (trifluoromethyl) benzoyl chloride. Subsequently, the acid chloride is reacted with a reducing agent, such as lithium aluminum hydride, in a suitable solvent, such as anhydrous ether, and the acid chloride group is then reduced to chloromethyl to obtain 1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene. This path step is relatively clear, but lithium aluminum hydride has strong reducing properties, and the operation needs to be cautious, and the reaction conditions are more stringent.
    Second, 2,4-bis (trifluoromethyl) toluene is used as the raw material. It allows 2,4-bis (trifluoromethyl) toluene to react with N-chlorosuccinimide (NCS) in a suitable solvent, such as carbon tetrachloride, in the presence of an initiator, such as benzoyl peroxide. This reaction is a radical substitution reaction. NCS provides chlorine radicals to attack the methyl group of toluene and substitutes to produce 1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene. The raw materials for this method are relatively easy to obtain, and the reaction conditions are relatively mild. However, side reactions may occur during the reaction process, and the reaction conditions need to be carefully adjusted to improve the selectivity of the product.
    Third, 2,4-bis (trifluoromethyl) bromobenzene is used as the starting material. First, 2,4-bis (trifluoromethyl) bromobenzene is reacted with magnesium chips in anhydrous ether to make Grignard's reagent 2,4-bis (trifluoromethyl) phenylmagnesium bromide. Then the Grignard's reagent is reacted with formaldehyde to generate the corresponding alcohol. Finally, the alcohol hydroxyl group is converted into chloromethyl by chlorination reagent, such as thionyl chloride, and the target product 1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene can also be obtained. This synthesis route has a little more steps, but each step is more classic and easy to control. As long as the operation process is strictly followed, a higher yield can be obtained.
    What are the precautions for 1- (Chloromethyl) -2,4-Bis (Trifluoromethyl) Benzene in storage and transportation?
    1 - (chloromethyl) - 2,4 - bis (trifluoromethyl) benzene is a chemical substance, and care must be taken when storing and transporting it.
    When storing, the first environment. It should be placed in a cool, dry and well-ventilated place, away from fires and heat sources. This is because it has certain chemical activity, high temperature or open flame is easily dangerous. And it needs to be placed separately from oxidizing agents, strong bases and other substances to prevent chemical reactions. Because of its active nature, contact with other substances or react violently, endangering safety.
    Furthermore, storage containers are also crucial. A well-sealed container must be used to prevent it from evaporating and escaping. Due to its volatile gas or toxicity and irritation, it endangers the human body and the environment. And the material of the container should be compatible with the chemical, and it should not react with it to ensure stable storage.
    As for transportation, there are also many details. Transportation vehicles must meet safety standards and be equipped with corresponding fire and emergency equipment. During transportation, it is necessary to ensure that the container is stable and will not collide or tip over. Due to collision or damage to the container, the chemical leaks, causing serious consequences.
    The escort personnel also need professional training and are familiar with the nature of this substance and emergency treatment methods. In the event of an accident such as a leak, they can respond quickly and correctly to reduce hazards. And the transportation route planning should also be careful to avoid densely populated areas and environmentally sensitive areas to reduce risks. In this way, the safe storage and transportation of 1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene can be guaranteed.
    What are the environmental effects of 1- (Chloromethyl) -2,4-Bis (Trifluoromethyl) Benzene?
    1 - (chloromethyl) - 2,4 - bis (trifluoromethyl) benzene, the impact of this substance on the environment should not be underestimated. Looking at its chemical structure, the groups containing chloromethyl and ditrifluoromethyl have unique properties or have various effects on environmental factors.
    Bearing the brunt, it is volatile to the atmospheric environment, escapes into the atmosphere, or participates in photochemical reactions. Under specific conditions, chlorine atoms and fluorine atoms can trigger a series of chain reactions, interfere with the balance of free radicals in the atmosphere, and then affect the oxidation capacity of the atmosphere. And it may pose a potential threat to the ozone layer. Although it is weaker than traditional chlorofluorocarbons, it cannot be ignored for long-term accumulation.
    As for the aquatic environment, if this substance enters the water body, it is easily adsorbed on the surface of suspended particles due to its hydrophobicity and chemical stability, or insoluble in water. It migrates with the water flow, or settles into the bottom sediments, and persists in the aquatic ecosystem for a long time. Its toxicity or toxic effect on aquatic organisms, interferes with the physiological metabolism, reproduction and other processes of aquatic organisms, and affects biodiversity.
    In the soil environment, it adsorbs on the surface of soil particles, affecting the physical and chemical properties of the soil. And due to the slow degradation of microorganisms, or the continuous accumulation in the soil, it changes the structure and function of the soil microbial community, and affects the material cycle and energy conversion of the soil ecosystem.
    Because of its stable chemical properties, it is difficult to degrade in the environment, or is transmitted and bioenriched through the food chain. After ingestion of low-trophic level organisms, the concentration in high-trophic level organisms may increase significantly, threatening organisms and even human health.
    In summary, 1- (chloromethyl) -2,4-bis (trifluoromethyl) benzene has potential effects in various environmental media, which is related to ecological balance and biological security. It is urgent to study in depth to understand its mechanism of action, find appropriate strategies to deal with it, and protect the ecological environment.