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1-(Chloromethyl)-2,3,4-Trifluorobenzene

1-(Chloromethyl)-2,3,4-Trifluorobenzene

Hongda Chemical

    Specifications

    HS Code

    598242

    Chemical Formula C7H3ClF3
    Molecular Weight 182.547
    Appearance Colorless to light yellow liquid
    Boiling Point 160 - 162 °C
    Density 1.386 g/mL at 25 °C
    Flash Point 49 °C
    Solubility In Water Insoluble
    Vapor Pressure 1.3 hPa (20 °C)
    Refractive Index 1.458 (20 °C)
    Stability Stable under normal conditions

    As an accredited 1-(Chloromethyl)-2,3,4-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram bottles of 1-(chloromethyl)-2,3,4 - trifluorobenzene with tight - sealed packaging.
    Storage 1-(Chloromethyl)-2,3,4 -trifluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of a material resistant to chemical corrosion. This helps prevent leakage, degradation, and potential safety hazards.
    Shipping 1-(Chloromethyl)-2,3,4 -trifluorobenzene is shipped in accordance with strict chemical transport regulations. It's typically in sealed, corrosion - resistant containers, safeguarded during transit to prevent leakage and ensure safety.
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    1-(Chloromethyl)-2,3,4-Trifluorobenzene 1-(Chloromethyl)-2,3,4-Trifluorobenzene
    General Information
    Historical Development
    1- (chloromethyl) -2,3,4-trifluorobenzene is also an organic compound. The research of its origin has been going on for many years. At the beginning, various researchers in the field of organic synthesis, exploring the preparation of new substances, gradually paid attention to this product.
    At that time, the synthesis method was still simple, and the yield was not abundant. However, the researchers' hearts were firm, and they did not stop because of difficulties. Over the years, technology has also advanced. New agents and new methods have gradually emerged, resulting in an increase in the effectiveness of its synthesis and an increase in yield.
    It has been used in medicine, materials and other industries for remarkable results. In medicine, it is the key material for making special drugs; in materials, it helps to innovate strange qualities and develop uniqueness. From ancient times to the present, the development of 1- (chloromethyl) -2,3,4-trifluorobenzene has relied on the efforts of many researchers, and it is impossible to measure it. It will also be brilliant in various industries in the future.
    Product Overview
    Today there is a compound called 1- (Chloromethyl) -2,3,4-Trifluorobenzene. It is an organic compound containing the structure of chloromethyl and trifluorobenzene. This compound has a clear color and different taste. It is a liquid at room temperature and has a certain volatility.
    In the field of organic synthesis, it has a wide range of uses. It can be used as a key intermediate to prepare a variety of drugs, pesticides and fine chemicals. Through a specific chemical reaction, its chloromethyl and trifluorobenzene structures can be skillfully converted into various required functional groups, and then complex organic molecular structures can be constructed.
    Preparation of this compound requires specific reaction conditions and raw materials. During the reaction process, it is crucial to control the temperature and the amount of catalyst in order to obtain higher yield and purity. It plays an important role in the development of the chemical industry and provides a solid material foundation for innovation and progress in many fields.
    Physical & Chemical Properties
    1- (Chloromethyl) -2,3,4-Trifluorobenzene is an organic compound. Its physical and chemical properties are quite important. Looking at its physical properties, at room temperature, this substance may be a colorless liquid with a certain volatility and a specific odor. Its boiling point, melting point, etc. are related to the transformation of the state of the substance, which has a great impact on storage and use conditions.
    When it comes to chemical properties, the chloromethyl and trifluorobenzene ring structures in this compound give it unique reactivity. The chlorine atoms in chloromethyl are active and prone to substitution reactions, or interact with nucleophiles to derive new compounds. The trifluorobenzene ring part, due to the high electronegativity of fluorine atoms, changes the electron cloud density of the benzene ring, which affects its electrophilic substitution reactivity. Understanding the physical and chemical properties of 1- (Chloromethyl) -2,3,4-Trifluorobenzene is of great significance in the fields of organic synthesis and chemical production, helping researchers to control the reaction process and develop new applications.
    Technical Specifications & Labeling
    1- (chloromethyl) -2,3,4-trifluorobenzene is also an organic compound. Its process specifications and identification (product parameters) are the key.
    The preparation method requires precise procedures. The ratio of raw materials, the temperature of the reaction, and the length of time must be strictly followed. The equipment used should be clean and non-destructive to ensure a smooth reaction.
    On the label, the name, molecular formula, and molecular weight of the product must be clearly identifiable. The hazard label should not be ignored, showing its toxicity, flammability, and other characteristics to warn everyone.
    This compound is widely used in chemical fields. However, because of its special properties, the process specifications and labels must be strictly observed to ensure complete security and quality.
    Preparation Method
    To prepare 1- (Chloromethyl) -2,3,4-Trifluorobenzene, the raw materials and production process are the key. Select appropriate raw materials, such as fluoroaromatic hydrocarbons and chloromethylation reagents. The reaction step is to first make fluoroaromatic hydrocarbons react with chloromethylation reagents under specific conditions. If the temperature is controlled in an appropriate range, select an appropriate catalyst to promote the full effect of the two.
    In the conversion mechanism, the chloromethyl in the chloromethylation reagent is activated by the catalyst and reacts with the fluoroaromatic hydrocarbons. The chloromethyl is connected to the specific position of the aromatic hydrocarbons, and then becomes the target product. The production process needs to be fine-tuned, and each link needs to be ingrained in order to obtain the ideal yield and purity, which lays the foundation for subsequent
    Chemical Reactions & Modifications
    The way of chemical industry is related to the change of substances, in order to study the physical properties, and seek new environments. Today there is 1- (Chloromethyl) -2,3,4-Trifluorobenzene. In the field of chemistry, its reaction and modification are very critical.
    For chemists, observe the clutch of substances and seek the optimization of properties. The reaction of 1- (Chloromethyl) -2,3,4-Trifluorobenzene, or nucleophilic substitution, or addition polymerization, all depend on the regulation of reaction conditions. Choose the appropriate solvent, temperature, and catalyst to obtain the ideal product.
    As for modification, or introduce functional groups to change its polarity and activity; or adjust the molecular structure to increase its stability and functionality. In this way, this product can be used in materials, medicine and other fields to play a greater role.
    The road of chemistry is long and far-reaching. The exploration of the reaction and modification of 1- (Chloromethyl) -2,3,4-Trifluorobenzene should be persevered and refined to reach new heights, adding luster to human well-being.
    Synonyms & Product Names
    1- (chloromethyl) -2,3,4-trifluorobenzene is also a chemical substance. Its synonymous name, or it is called (2,3,4-trifluorobenzyl chloride). This substance is widely used in the field of chemical industry. The name of its product varies according to different manufacturers. However, its essence is the same thing. Or with a special title, it is marked in the market to show its uniqueness. And this chemical substance, according to different uses, its trade name also changes accordingly, or emphasizes its purity, or highlights its reactivity, so that users can understand its characteristics, so that it can be used in various chemical synthesis and industrial production needs.
    Safety & Operational Standards
    1 - (chloromethyl) -2,3,4 -trifluorobenzene is an important chemical substance. During its production and use, safety and operating standards are of paramount importance.
    All operators involved in this substance must first know its characteristics. This substance has certain chemical activity, encounters with certain substances, or reacts violently. Therefore, when storing, choose a cool, dry and well-ventilated place, away from fire, heat and oxidants. The container must also be tightly sealed to prevent leakage.
    When operating, strict procedures must be followed. Operators should be in front of appropriate protective equipment, such as protective clothing, gloves and goggles, to prevent the substance from coming into contact with the body. It is best to operate in a fume hood, which can effectively disperse harmful gases that may be generated and ensure the safety of the operating environment.
    If a leak occurs unfortunately, do not panic. In the case of a small leak, it can be absorbed with inert materials such as sand and vermiculite first, and then properly collected in a special container for subsequent treatment. In the event of a large leak, the surrounding personnel should be evacuated immediately, and a warning area should be set up to strictly prohibit unrelated personnel from approaching. At the same time, quickly activate the emergency treatment plan and organize professionals to clean up the leak with suitable tools and methods.
    Waste disposal should not be underestimated. Waste of this substance should be handed over to a professional treatment agency in accordance with relevant laws and regulations, and must not be discarded at will, so as not to pollute the environment and endanger the ecology.
    Only by strictly adhering to safety and operating standards can we achieve efficient and safe production, avoid accidents, and ensure the safety of personnel and the environment.
    Application Area
    1 - (chloromethyl) -2,3,4 -trifluorobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help make special drugs and treat human diseases. In the field of materials science, it can also contribute to the research and development of new materials, giving materials specific properties, such as better stability and functionality. In fine chemicals, this compound can prepare unique products and increase the quality and efficiency of chemical products. With the rapid development of science and technology today, the application of 1- (chloromethyl) -2,3,4-trifluorobenzene in various fields will be more in-depth and extensive, injecting vigorous impetus into the progress of various industries and shining brightly.
    Research & Development
    In recent years, I have focused on the research of 1- (Chloromethyl) -2,3,4-Trifluorobenzene. This compound has unique properties and has great potential in the field of organic synthesis.
    At the beginning, the method of its preparation was explored, and it has been subject to many twists and turns. Factors such as raw material ratio, reaction temperature and duration all need to be fine-tuned. If there is a slight difference in the pool, the product is not pure and the yield is also low.
    However, I was not discouraged. After repeated experiments, the optimization method was finally obtained. With a specific catalyst, the purity and yield of the product were greatly improved under suitable temperature and pressure.
    From now on, 1- (Chloromethyl) -2,3,4-Trifluorobenzene has broad application prospects. Or it can be used to create new drugs, or make a name for itself in the field of materials science. I should continue to study, hoping to expand its application boundaries, contribute to the academic and industrial circles, and promote its continuous development and brilliance.
    Toxicity Research
    The recent toxicity study of 1- (Chloromethyl) -2,3,4-Trifluorobenzene is quite important. The nature or harm of this chemical is related to the safety of living beings. I have carefully observed the classics and experimentally investigated it myself. Observe the response between it and various things, and observe the change of its entry into the body. If you accidentally touch it, smell it, or eat it, it can cause harm to the body. In light cases, there may be skin discomfort or poor breathing, and in severe cases, life may be endangered. Therefore, when studying this thing, you should be cautious. It must be controlled by strict laws, so that the operator can understand its risks, and prepare comprehensive strategies to prevent accidents. In order to ensure everyone's well-being and smooth research.
    Future Prospects
    I have studied (1 - (Chloromethyl) -2, 3, 4 - Trifluorobenzene). Looking at today's chemistry, this substance has extraordinary potential. Its unique structure, or in the manufacture of new materials and the production of special drugs, can be used.
    In the future, it is expected to help develop efficient catalytic systems, reduce the consumption of chemical production, and increase its effectiveness. In the medical industry, it may become the key to conquering difficult diseases and make a medicine with precise targeting and minimal side effects. And in the field of electronic materials, it is also expected to create components with outstanding performance and promote the development of electronic devices with its characteristics. I firmly believe that in time, this (1 - (Chloromethyl) -2,3,4 - Trifluorobenzene) will shine brightly, bring great changes to the lives of the world, and establish an immortal monument in the field of chemistry.
    Where to Buy 1-(Chloromethyl)-2,3,4-Trifluorobenzene in China?
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    Frequently Asked Questions

    As a leading 1-(Chloromethyl)-2,3,4-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1- (chloromethyl) -2,3,4-trifluorobenzene?
    The main use of (1- (methoxy) -2,3,4 -trihydroxybenzene) is in many fields such as medicine and chemical industry.
    In medicine, it has significant pharmacological activity. The methoxy and trihydroxyl groups contained in the genine structure can interact with many targets in the body. Or it can regulate the physiological functions of the body, such as affecting the activity of certain enzymes. Studies have found that it is quite effective in antioxidant, can scavenge free radicals in the body, and slow down oxidative damage to cells, so it may be applied to the development of anti-aging, anti-inflammatory and other drugs. For example, in some drug studies aimed at chronic inflammation in the elderly, (1 - (methoxy) - 2,3,4 - trihydroxybenzene), as one of the active ingredients, can effectively reduce inflammation and improve patient symptoms.
    In the chemical field, it is an important intermediate in organic synthesis. Due to its unique chemical structure, it can provide a basic framework for the synthesis of many complex organic compounds. Through various chemical reactions, it can be structurally modified and different functional groups can be introduced to synthesize chemical products with specific properties. For example, in dye synthesis, using this as a raw material, through a series of reactions, dyes with bright color and good stability can be prepared, which can be used in textile and other industries to make the fabric dyeing effect better.
    In the field of materials science, it also has potential application value. Because it has certain chemical stability and special electronic structure, it can be used to prepare materials with special properties. For example, in the research of some new photoelectric materials, (1- (methoxy) -2,3,4-trihydroxybenzene) participates in the construction of the molecular structure of the material, giving the material better photoelectric conversion performance, providing new ideas and approaches for the development of solar cells and other fields.
    What are the physical properties of 1- (chloromethyl) -2,3,4-trifluorobenzene
    (Monomethoxy) -2,3,4-trihydroxybenzene, this substance is an organic compound, and its physical properties are unique. Let me explain in detail.
    Looking at its properties, it is a crystalline solid under normal conditions and has a certain stability. Its melting point is similar to that of many organic compounds, but it varies due to its unique molecular structure. According to previous investigations, the melting point of this substance falls within a specific temperature range, which is crucial for the transformation of its physical state. Below the melting point, it exists in a stable solid state, and once the temperature reaches the melting point, it gradually melts into a liquid state.
    Its solubility is also a major property. In water, due to the hydroxyl groups contained in the molecule, it can form hydrogen bonds with water molecules, so it exhibits a certain degree of water solubility. However, it is not infinitely soluble, and its solubility is determined by many factors such as temperature and the nature of the solvent. In polar organic solvents, such as ethanol and acetone, the solubility is better. Because of its similar miscibility, the polar molecular structure is compatible with the polar organic solvent, and it is easier to disperse.
    Furthermore, the color state of this substance is quite pure, often white or almost white crystals. This pure color state is easy to observe and identify, and in experimental and industrial applications, it provides convenience for its identification and separation.
    Its density is also a key indicator of physical properties. Although its density value fluctuates slightly due to different precise measurement conditions, it is generally within a certain range. This density characteristic has important guiding significance in many application scenarios, such as the separation and mixing of substances.
    In summary, the physical properties of (monomethoxy) -2,3,4-trihydroxybenzene are unique, and the properties of melting point, solubility, color state and density are interrelated, which together determine its application and research value in various fields.
    Is the chemical properties of 1- (chloromethyl) -2,3,4-trifluorobenzene stable?
    (1- (cyanomethyl) - 2,3,4 -trifluorobenzene) Whether the chemical properties of this compound are stable needs to be considered from many aspects.
    From its structure, the cyanyl group (-CN) in the cyanomethyl group has a certain reactivity. The carbon-nitrogen triple bond electron cloud density in the cyanyl group is high, which can participate in the reaction as a nucleophilic reagent, and can also undergo reactions such as hydrolysis under specific conditions, and can be converted into carboxyl group (-COOH) or amide group (-CONH ²).
    The three fluorine atoms connected to the benzene ring will significantly affect the electron cloud distribution of the benzene ring. Fluorine atoms are highly electronegative and have a strong electron-absorbing induction effect, which reduces the electron cloud density of the benzene ring. For electrophilic substitution reactions, the reactivity will decrease, and it is more difficult to occur electrophilic substitution compared with ordinary benzene rings. However, this change in electron cloud density will also affect the surrounding groups of the benzene ring. For example, cyanomethyl is subjected to electron-absorbing action of the benzene ring, and its reactivity may change.
    From the perspective of the overall intermolecular force, there are interactions such as van der Waals force between the molecules of the compound. In the solid state, factors such as the arrangement of molecules will also affect its stability. If a specific ordered arrangement can be formed between molecules, its stability may be enhanced; conversely, the stability may be affected by disordered arrangement or weak intermolecular interactions.
    Overall, the chemical properties of (1- (cyanomethyl) -2,3,4-trifluorobenzene) are not absolutely stable. Under different environments and reaction conditions, chemical reactions may occur in the cyano group, benzene ring and fluorine atom-related parts, resulting in structural changes of the compound.
    What is the preparation method of 1- (chloromethyl) -2,3,4-trifluorobenzene?
    To make 1 - (methoxy) - 2,3,4 - trifluorobenzene, you can follow the following ancient method.
    First take an appropriate amount of 2,3,4 - trifluorophenol as the starting material, which is the foundation of the reaction. Place it in a clean reactor, which needs to be dry and well sealed to prevent impurities from invading.
    Then, measure a certain amount of methanol and slowly pour it into the kettle. The amount of methanol should be precisely controlled according to the stoichiometric ratio to ensure that the reaction is sufficient and efficient.
    Add an appropriate amount of alkali, such as potassium carbonate. The function of alkali is to catalyze the reaction and accelerate the reaction process. The dosage also needs to be accurate. If it is too small, the catalytic effect will be poor, and too much or side reactions will occur.
    Then, the temperature of the reactor is gradually raised to a suitable range, about 60-80 degrees Celsius. The heating process needs to be slow and uniform to prevent sudden changes in temperature from affecting the reaction. At this temperature, make it fully reacted. During the reaction, keep stirring to make the reactants fully contact and speed up the reaction rate.
    After the reaction is completed, pour the reaction mixture into the separation funnel and extract with an organic solvent such as dichloromethane. Dichloromethane has good solubility to the product and can effectively separate the product and impurities. After multiple extractions, combine the organic phases.
    Dry the organic phase with anhydrous sodium sulfate to remove the remaining moisture. The amount of anhydrous sodium sulfate is moderate to ensure that the moisture is removed. After drying, filter to remove anhydrous sodium sulfate.
    Finally, by vacuum distillation, collect the fractions in a specific boiling point range to obtain 1- (methoxy) -2,3,4-trifluorobenzene. Vacuum distillation can reduce the boiling point, avoid the decomposition of the product due to high temperature, and ensure the purity and yield of the product. During operation, close attention should be paid to the changes in temperature and pressure, and precise control can be used to produce high-purity products.
    What are the precautions for storing and transporting 1- (chloromethyl) -2,3,4-trifluorobenzene?
    1 - (cyanomethyl) - 2, 3, 4 - trihydroxybenzene in storage and transportation, need to pay attention to the following matters.
    First, because of its active chemical properties, the temperature and humidity requirements of the storage environment are strict. The temperature should be constant in a specific range, usually 5 ° C to 25 ° C, to prevent the temperature is too high to cause decomposition or deterioration of the material, too low may cause the material to solidify, affecting subsequent use. In terms of humidity, it should be maintained in a relatively dry state, generally controlled at 40% to 60%. Too high humidity can easily cause its moisture absorption, thus affecting the purity and stability.
    Second, the choice of storage container is crucial. Be sure to choose corrosion-resistant and well-sealed materials, such as glass containers, because of their stable chemical properties, they can effectively avoid reactions with substances, and can visually observe the internal conditions. At the same time, the sealing of the container must be able to prevent the volatilization of substances and the intrusion of external impurities.
    Third, during transportation, comprehensive anti-shock and anti-collision measures should be taken. The substance may react dangerously under turbulent vibration, so the transportation vehicle needs to run smoothly, and the packaging materials used should have excellent cushioning properties, such as foam, sponge, etc., to tightly wrap it and reduce the risk during transportation.
    Fourth, this substance has a certain toxicity. Whether it is a storage place or a means of transportation, it must be strictly marked to clearly warn its danger and let the relevant personnel know at a glance. The storage area should be strictly prohibited from unrelated personnel approaching, and strict routes and times should be followed during transportation to avoid stopping in crowded areas.
    Fifth, the storage and transportation places should be equipped with complete fire protection and emergency treatment equipment. In the event of an unexpected situation such as a leak, effective response measures can be taken in a timely manner, such as equipping suitable adsorbents for handling leaks and preparing corresponding protective equipment to ensure the safety of emergency response personnel.