Hongda Chemical
Products
Home  /  Products  / 

1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene

1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene

Hongda Chemical

    Specifications

    HS Code

    224125

    Chemical Formula C7H5ClFNO2
    Molar Mass 191.57 g/mol
    Appearance Solid (usually)
    Melting Point Data needed
    Boiling Point Data needed
    Density Data needed
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane
    Flash Point Data needed
    Vapor Pressure Data needed
    Acidity Basicity Weakly acidic due to the nitro group
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

    As an accredited 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 1 - chloro - 5 - fluoro - 2 - methyl - 4 - nitrobenzene packaged in a sealed plastic drum.
    Storage 1 - Chloro - 5 - fluoro - 2 - methyl - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent leakage and exposure to air and moisture, which could potentially lead to chemical reactions or degradation. Ensure storage areas are locked and inaccessible to unauthorized personnel.
    Shipping 1 - Chloro - 5 - fluoro - 2 - methyl - 4 - nitrobenzene is shipped in well - sealed, corrosion - resistant containers. Transport follows strict chemical safety regulations, ensuring proper handling to prevent leakage and maintain product integrity.
    Free Quote

    Competitive 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365186327

    Email: info@alchemist-chem.com

    1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene
    General Information
    Historical Development
    1-Chloro-5-fluoro-2-methyl-4-nitrobenzene is also an organic compound. Its trace began in the process of modern chemical evolution. At that time, chemists studied the principles of physical properties and chemical synthesis, and dedicated themselves to exploring the field of new substances.
    At the beginning, the analysis of its structure and properties was difficult to study. Chemists used simple tools and simple methods to explore its mysteries. With the passage of time, science and technology have gradually advanced, the art of analysis has become more refined, and the method of synthesis has also advanced.
    All the sages worked tirelessly, repeatedly deducing the reaction conditions and the ratio of raw materials. Since then, the synthesis of this compound has gradually improved, and the yield has also increased. Its application in the fields of medicine and materials has also gradually attracted attention. Since the beginning of ignorance, the development of 1-chloro-5-fluoro-2-methyl-4-nitrobenzene, the development of 1-chloro-5-fluoro-2-methyl-4-nitrobenzene, is one of the evidence of the evolution of chemical history, demonstrating the spirit of human knowledge and innovation.
    Product Overview
    1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene is an important chemical substance. It has a unique structure, with chlorine atoms, fluorine atoms, methyl groups and nitro groups cleverly attached to the benzene ring.
    This compound is quite useful in many fields. In the field of organic synthesis, it is often used as a key intermediate, and can be converted into a variety of organic compounds with special functions through various chemical reactions. Its unique chemical properties are derived from the interaction of various substituents on the benzene ring.
    However, the preparation of this compound requires rigorous operation. Reaction conditions such as temperature, pressure, reactant ratio, etc. need to be precisely controlled, with slight deviations, or the yield may decrease and side reactions increase.
    Extra caution is also required in storage and transportation. Due to its lively nature, there may be safety hazards in case of specific conditions. Only proper handling can ensure the safety and efficiency of its application.
    Physical & Chemical Properties
    1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene is an organic compound. Its physical and chemical properties are quite important to scholars. Looking at its shape, at room temperature, or in a crystalline state, it is light yellow in color and has a special odor. Its melting point and boiling point are also fixed. The melting point is about [X] ° C, and the boiling point is around [X] ° C. This is related to the characteristics of its intermolecular force and structure.
    In terms of its solubility, it is soluble in organic solvents such as ethanol and ether, but difficult to dissolve in water. This is due to the difference between molecular polarity and water molecules. Chemically, due to its chlorine, fluorine, nitro and other functional groups, it is active and can react with a variety of reagents. Nitro has strong electron absorption, which reduces the electron cloud density of benzene ring, which is conducive to nucleophilic substitution; halogen atoms can undergo substitution and elimination reactions under suitable conditions. This compound has a wide range of uses in the field of organic synthesis and can be used as an intermediate to prepare many fine chemicals.
    Technical Specifications & Labeling
    1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene is an important chemical product. Its process specification and labeling (product parameters) are related to product quality and application.
    In terms of process specifications, the synthesis of this product requires strict control of the reaction conditions. The ratio of raw materials must be accurate, such as the amount of each reactant should be configured according to a specific ratio to ensure that the reaction is fully carried out. The reaction temperature is also critical, and it must be maintained in a suitable range, or it can be reacted at a constant temperature within a certain temperature range, so that the reaction can advance in the direction of generating the target product.
    When it comes to labeling (product parameters), purity is an important indicator, and high-purity products are more suitable for high-end applications. In addition, physical parameters such as melting point and boiling point cannot be ignored, which can help identify the authenticity and quality of the product. Precise control of process specifications and clear identification (product parameters) can ensure that 1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene is of high quality and meets diverse industrial needs.
    Preparation Method
    1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene is made in this product. The raw materials and production process, reaction steps and catalytic mechanism are very important.
    To make it, first take an appropriate amount of 2 - methyl - 4 - nitroaniline as the raw material and dissolve it in a specific solvent, such as glacial acetic acid. Then slowly drop in a fluorinated reagent, such as hydrogen fluoride pyridine, and control the temperature in a suitable range, about 0 ° C to 5 ° C. This step is a nucleophilic substitution reaction, and the fluorine atom replaces the amino group.
    After the reaction is completed, neutralize it in an alkali solution, such as sodium hydroxide solution, and precipitate the product. Then it is purified by extraction, distillation and other methods.
    In the catalytic mechanism, the selection of suitable catalysts, such as copper salts, can promote the reaction speed and reduce the activation energy. And the pH, temperature and reactant ratio of the reaction environment need to be precisely controlled to achieve high yield and purity, so as to prepare this fine chemical product.
    Chemical Reactions & Modifications
    Yu has dedicated himself to the study of chemical substances, recently focusing on 1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene. The chemical reaction and modification of this substance are of paramount importance.
    Looking at its reaction, various paths are feasible. The method of the past may have the disadvantages of being complicated and inefficient. If you want to improve, you should think of new ways. Or choose mild conditions to reduce energy consumption and pollution; or choose specific catalysts to promote the rapid reaction and increase the purity of the product.
    As for modification, it aims to add its characteristics. Or change its structure to make it more stable; or increase its functional groups to make it have different activities. In this way, the substance can be used in various fields such as materials, medicine, etc., or it can exhibit extraordinary effects, opening up new paths for scientific research and industry, and generating endless possibilities.
    Synonyms & Product Names
    1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene This chemical substance has a synonym and trade name related matters in ancient times. Although this precise chemical name was not available in the past, the research on related substances has long taken shape.
    View Today's 1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene, or has many synonymous names, and also has different product names. Due to the depth of chemical research, each research group and industrial field has been given different names according to their characteristics, uses, discovery process, etc.
    In the past, although the chemical investigation was not as accurate as it is today, the observation of the properties of matter has been advanced. Although there was no such precise name at that time, benzene compounds containing chlorine, fluorine, methyl, and nitro groups were already perceived. Later generations of science and technology advanced with each passing day, and the deeper the understanding of them, the more accurate the name was, and the synonyms and trade names became more and more diverse with the expansion of research and application.
    Safety & Operational Standards
    1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene is an important chemical product and is of paramount importance for its safety and handling practices.
    All handling of this substance shall be carried out in accordance with regulations. Operators should be fully prepared in advance and wear appropriate protective equipment such as protective clothing, protective gloves and goggles to prevent contact with skin and eyes, and must wear appropriate respiratory protective equipment to protect against harmful gases.
    In the operating area, good ventilation must be provided to avoid the accumulation of harmful gases. If there is an accidental leakage of this material, the first thing to do is to quickly evacuate the surrounding personnel, set up a warning area, and strictly prohibit unrelated people from approaching. Then, according to the leakage situation, take proper cleaning measures. If it is a small amount of leakage, it can be adsorbed with inert materials such as sand and vermiculite, collected and disposed of properly; if it is a large amount of leakage, it is necessary to build a dike or dig a pit for containment, and then transfer it to a special container with an explosion-proof pump and transport it to a designated place for disposal.
    When storing this material, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources, and avoid mixing with oxidants, acids, alkalis, etc., to prevent dangerous chemical reactions. At the same time, the storage area should be equipped with suitable materials to contain leaks.
    During transportation, it is also necessary to strictly follow the relevant regulations to ensure that the packaging is complete and firm, and to prevent collisions and leaks. Transportation vehicles should be equipped with the corresponding variety and quantity of firefighting equipment and leakage emergency treatment equipment.
    Only by strictly observing these safety and operating standards can we ensure the safety of personnel and protect the environment, so that the application of 1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene is smooth.
    Application Area
    1-Chloro-5-fluoro-2-methyl-4-nitrobenzene is also a good chemical product. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be a key intermediate to help create new drugs, cure various diseases, and benefit the common people. In the field of materials science, it can participate in the preparation of special materials, giving materials unique properties, such as enhanced stability and improved optical characteristics. It is also used in fine chemical production to produce many high value-added fine chemicals, enhancing the efficiency of industrial production. Due to its special structure and properties, this compound has great potential in various fields, shining like a star, illuminating the vast world of chemical applications and contributing to scientific and technological progress and social development.
    Research & Development
    In recent years, I have studied 1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene in the field of chemistry. At first, I wanted to understand its properties, so I measured it by various methods. Observe its shape, it is solid, the color is yellowish, and it flickers under light, like a mystery.
    Re-explore its chemical properties, and respond to various agents, and observe changes in detail. With the change of temperature and the difference in the amount of agent, observe the speed of its response, and whether the product is born. Observe it, and know that it should live under a certain environment, and it can become a new product, which is of special use.
    I think the development of this thing, if it is in the system of medicine, may be a new way. With its properties, it can be transformed into other things, and it can be used as an anti-disease agent to save people from suffering. I also think about the creation of materials, or it can give new materials, make them strong and tough, and use them in various utensils to promote the progress of work.
    On the road to research, although I encounter difficulties, I am determined. Every time I get something, I am overjoyed. I hope that in other years, this research will be successful, beneficial to the world, and it will live up to my heart.
    Toxicity Research
    1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene is a chemical compound that has attracted much attention in current chemical research. Our generation focuses on toxicity research and examines this substance in detail.
    After many experiments, it can be known that this compound has certain toxicity. In its molecular structure, the existence of chlorine, fluorine, nitro and other groups may be the key factors for toxicity. The strong electron absorption of nitro groups may change the activity of molecules and easily interact with molecules in vivo.
    Biological experiments show that it has a significant inhibitory effect on some cells. And percutaneous or inhalation route, or have adverse effects on organisms. Although it is not highly toxic, its potential harm cannot be ignored. We should be cautious and take comprehensive protection when researching and applying it, so as to avoid disasters to life and the environment, and hope to better understand its toxic nature and control its use.
    Future Prospects
    I have tasted and researched chemical products. In 1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene, I have thoughts and thoughts about its future development. In today's world, science and technology are changing day by day, and the chemical industry is following suit. Although this product is small, it has a wide range of uses, and it may be useful in the fields of medicine and materials.
    In the past, chemical products often opened new paths and created amazing works. I guess 1 - Chloro - 5 - Fluoro - 2 - Methyl - 4 - Nitrobenzene is the same. With time, scientific research can be refined, or it can be synthesized in medicine, help the development of new drugs, and solve the pain of the world; in the creation of materials, create special materials, and meet the needs of all parties.
    The future development is unlimited. Scientists should work together to explore its potential, make it shine in various industries, become the hope of our generation in the future, contribute to the progress of the world, realize our unfinished dreams, and develop the glow of chemical industry in the future.
    Where to Buy 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene in China?
    As a trusted 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene?
    1-Chloro-5-fluoro-2-methyl-4-nitrobenzene is one of the organic compounds. Its physical properties are important for many practical applications.
    The melting point of this compound is the temperature at which the substance changes from solid to liquid state. The melting point of 1-chloro-5-fluoro-2-methyl-4-nitrobenzene has been determined by many researchers to be within a specific range, but may vary slightly due to slight differences in measurement conditions. The value of this melting point is very useful in identifying and purifying the compound.
    Furthermore, the boiling point is the temperature at which a substance changes from a liquid state to a gaseous state under a specific pressure. The boiling point of 1-chloro-5-fluoro-2-methyl-4-nitrobenzene reflects the difficulty of its gasification. In the field of chemical production, knowing the boiling point, separation processes such as distillation can be reasonably designed to obtain high-purity products.
    Looking at its appearance, it usually takes a specific form. Either it is crystalline and has a certain crystal structure; or it is powdery, and the degree of particle fineness is also characteristic. This appearance characteristic can be an important clue in the preliminary identification of the compound.
    Discusses density, which is the mass of the substance per unit volume. The density of 1-chloro-5-fluoro-2-methyl-4-nitrobenzene is crucial for storage, transportation, and in some application scenarios involving hydrodynamics. The different densities determine its distribution in the mixed system.
    In terms of solubility, 1-chloro-5-fluoro-2-methyl-4-nitrobenzene has different solubility in various solvents. In organic solvents such as ethanol and ether, it may have a certain solubility, but in water, its solubility may be very low. This solubility characteristic affects the choice of chemical reaction medium and the strategy of product separation and purification.
    In addition, the volatility of the compound is also an important physical property. Volatility is related to the rate of its diffusion in the environment, which is of great significance to the safety assessment of its use scenarios. If the volatility is strong, special attention should be paid to ventilation and other measures during storage and use to prevent harm to the health of operators and cause safety accidents.
    What are the chemical properties of 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene?
    1-Chloro-5-fluoro-2-methyl-4-nitrobenzene is one of the organic compounds. It has unique chemical properties, which are described in detail by you.
    This compound contains chlorine, fluorine, methyl and nitro groups. The introduction of chlorine atoms and fluorine atoms changes the electron cloud distribution of the molecule, affecting its physical and chemical properties. Halogen atoms are electronegative and can increase the polarity of molecules, which has a significant effect on their solubility and boiling point. In chemical reactions, halogen atoms can be used as leaving groups to participate in nucleophilic substitution reactions. The electron cloud density of the benzene ring can be increased by methyl, which has an effect on the reactivity of the benzene ring. In the electrophilic substitution reaction, the reaction is more likely to occur in the ortho and para-sites of the benzene ring. The nitro group is a strong electron-absorbing group, which not only greatly reduces the electron cloud density of the benzene ring, but also greatly decreases the electrophilic substitution reactivity of the benzene ring, and makes the electron cloud distribution on the benzene ring uneven. In this compound, the presence of nitro has a profound impact on its chemical properties. In the reduction reaction, the nitro group can be reduced to other groups such as amino groups, and different compounds can be derived.
    Its chemical properties are active. Under appropriate conditions, halogen atoms can be replaced by various nucleophiles to form new derivatives. The substituent interaction on the benzene ring also determines its performance in various reactions. Because it contains a variety of groups with different properties, it can be used as an important intermediate in the field of organic synthesis to construct complex organic molecular structures through a series of reactions.
    What are the main uses of 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene?
    1-Chloro-5-fluoro-2-methyl-4-nitrobenzene has a wide range of uses. In the field of organic synthesis, it can be called a key intermediate. It can be converted into other organic compounds through a series of chemical reactions, such as the preparation of drugs, pesticides and dyes with specific structures.
    Let's talk about the preparation of drugs first. With this as the starting material, through ingeniously designed reaction steps, molecular structures with specific biological activities can be constructed. Due to its functional groups such as chlorine, fluorine, methyl and nitro, it can participate in various reactions and affect the distribution of electronic clouds and spatial structures of drug molecules, thus endowing drugs with unique pharmacological properties.
    In the field of pesticides, it can be used as an important intermediate for the synthesis of new pesticides. By reacting with other compounds, pesticides with high insecticidal, bactericidal or herbicidal properties can be synthesized. For example, through reasonable modification, pesticides have stronger affinity and activity for specific target organisms, and reduce the impact on non-target organisms, improving pesticide selectivity and environmental friendliness.
    As for the dye industry, 1-chloro-5-fluoro-2-methyl-4-nitrobenzene can be used to synthesize dyes with bright color and good fastness. The functional groups in its structure can combine with other organic molecules to form a conjugated system, which is crucial for the color and stability of dyes. By changing the reaction conditions and the proportion of reactants, the color and properties of dyes can be adjusted to meet the needs of different textile materials and dyeing processes.
    In short, 1-chloro-5-fluoro-2-methyl-4-nitrobenzene plays an important role in organic synthesis, pharmaceuticals, pesticides and dyes, and is of great significance to promote the development of related fields.
    What are 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene synthesis methods?
    The synthesis method of 1-chloro-5-fluoro-2-methyl-4-nitrobenzene has various paths. First, chlorine and fluorine atoms can be introduced by halogenation reaction starting from suitable aromatic compounds. If methyl nitrobenzene is selected as the raw material, under specific reaction conditions, chlorine reagents and fluorine reagents are used separately. The chlorine reagents used include thionyl chloride, phosphorus trichloride, etc.; fluorine reagents such as potassium fluoride, etc. During the reaction, the temperature, reaction time and reagent dosage need to be carefully controlled. If the temperature is too high, it may cause more side reactions and damage the purity of the product; if the temperature is too low, the reaction rate will be slow and take a long time.
    In addition, it can be achieved by nitro substitution reaction. The methyl and halogen atoms are introduced into the benzene ring first, and then the nitro group is introduced into the benzene ring at the appropriate position through nitrification reaction. The nitrification reaction usually uses a mixed acid system of nitric acid and sulfuric acid, which has strong oxidation and can effectively achieve nitro substitution. However, the reaction is violent, and the reaction conditions need to be carefully controlled to prevent excessive nitrification, and the waste acid must be properly disposed to avoid environmental pollution.
    Or the strategy of gradually constructing the benzene ring is adopted. The precursor of the benzene ring with some substituents is first synthesized by organic synthesis, and then the other substituents are introduced in sequence. Although this method is cumbersome, it has better selective control of the reaction and can obtain high-purity products. For example, the benzene ring structure and each substituent are gradually constructed by specific nucleophilic substitution reactions, electrophilic substitution reactions, etc.
    All synthesis methods have their own advantages and disadvantages. In actual operation, it is necessary to comprehensively weigh factors such as raw material availability, cost considerations, and product purity requirements, and make careful choices to achieve the synthesis goal.
    1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene what are the precautions during storage and transportation?
    1-Chloro-5-fluoro-2-methyl-4-nitrobenzene is also an organic compound. During storage and transportation, many matters need to be paid attention to.
    The first to bear the brunt, the storage must be cool and dry. This compound is easy to decompose when heated, and if placed in a high temperature, it may cause a runaway reaction and cause danger. Therefore, it is essential to choose a place with a suitable temperature, away from heat sources and fire sources.
    In addition, it is toxic and corrosive, and must be stored separately from oxidants, reducing agents, acids, bases and other substances. If mixed with each other, or react violently, it can lead to serious consequences such as leakage and explosion.
    The packaging must be tight. Make sure that the packaging is not damaged or leaked to prevent substances from escaping and endangering the environment and personal safety. When transporting, choose suitable means of transportation and follow relevant regulations.
    The handling process also needs to be cautious. Light loading and light unloading, do not drop or heavy pressure, so as not to damage the packaging and cause material leakage. Operators must wear appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to prevent contact injuries.
    During transportation, pay close attention to environmental factors such as temperature and humidity. In case of extreme weather, corresponding measures should be taken to ensure transportation safety. And transportation route planning should avoid sensitive areas such as water sources and densely populated areas to prevent accidental leakage from causing widespread harm.