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1-Chloro-4-Nitro-2-(Trifluoromethyl)-Benzene

1-Chloro-4-Nitro-2-(Trifluoromethyl)-Benzene

Hongda Chemical

    Specifications

    HS Code

    787066

    Chemical Formula C7H3ClF3NO2
    Molecular Weight 225.55
    Appearance Typically a solid
    Physical State At Room Temperature Solid
    Melting Point Data may vary, but generally in a certain temperature range
    Boiling Point Specific value depending on conditions
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in some common organic solvents like dichloromethane
    Density A specific density value depending on conditions
    Flash Point Value relevant for flammability assessment
    Hazard Class May fall into hazardous chemical classes due to components

    As an accredited 1-Chloro-4-Nitro-2-(Trifluoromethyl)-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1 - chloro - 4 - nitro - 2 - (trifluoromethyl) - benzene in 500g bottles for chemical packaging.
    Storage 1 - Chloro - 4 - nitro - 2 - (trifluoromethyl) - benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. It is best stored in a tightly - sealed container made of corrosion - resistant materials like glass or certain plastics. Keep it separate from oxidizing agents, reducing agents, and other reactive chemicals to prevent potential reactions.
    Shipping 1 - chloro - 4 - nitro - 2 - (trifluoromethyl) - benzene is a chemical. Shipping should comply with strict hazardous material regulations. It must be properly packaged, labeled, and transported by carriers licensed for such chemicals.
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    1-Chloro-4-Nitro-2-(Trifluoromethyl)-Benzene 1-Chloro-4-Nitro-2-(Trifluoromethyl)-Benzene
    General Information
    Historical Development
    I have heard of the chemical industry, with each passing day, all kinds of compounds have emerged. Today there is 1 - Chloro - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene, and its prosperity is the work of many talents.
    At the beginning, everyone explored the field of chemistry and was thirsty for knowledge. After countless experiments, they either encountered setbacks or made little progress. The public worked hard, with scientific methods and rigorous hearts, analyzed physical properties, and explored the way of preparation.
    Years have passed, and the technology has gradually matured. From the initial ignorance to understanding its reaction mechanism and controlling its reaction conditions, it can produce stable output. Its use in industry and scientific research has gradually expanded, helping to move forward in many fields. The development of this compound is like a long river rushing, originating from a trickle and gradually becoming a torrent, adding to the progress of chemistry and opening up more possibilities for future generations.
    Product Overview
    1 - Chloro - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene is an important chemical substance. Its appearance is [specific appearance, need to be supplemented because it is not provided], and it has unique physical and chemical properties. This substance has a wide range of uses in the field of chemical research, and is often used as a key intermediate for the synthesis of a variety of complex organic compounds.
    Preparation of this compound requires a series of fine chemical steps. Usually starting with [relevant starting materials, need to be supplemented according to the actual situation], under specific reaction conditions, such as [specific temperature, catalyst and other reaction conditions, need to be supplemented according to the actual situation], it is obtained through a multi-step reaction.
    In terms of storage, it should be placed in a cool, dry and well-ventilated place, away from fire sources and oxidants, to prevent dangerous reactions. During use, because it may be toxic and irritating, it is necessary to strictly follow safety procedures during operation and take protective measures to ensure the safety and health of experimental personnel.
    Physical & Chemical Properties
    1 - Chloro - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene is an organic compound. Its physical properties are colorless to light yellow liquid at room temperature, with a special odor. Its boiling point is about a certain value, because accurate data need to be determined by experiments. The density is higher than that of water, insoluble in water, but soluble in a variety of organic solvents, such as ethanol, ether, etc.
    In terms of its chemical properties, chlorine atoms, nitro groups and trifluoromethyl groups in the molecule give it unique reactivity. Nitro has strong electron absorption, which reduces the density of electron clouds in the benzene ring, making the electrophilic substitution reaction more difficult, but conducive to nucleophilic substitution. Chlorine atoms can undergo substitution reactions and can be replaced by various nucleophilic reagents. The presence of trifluoromethyl enhances the stability and fat solubility of the compound, and also affects its biological activity and application. The study of the physicochemical properties of this compound is of great significance in the fields of organic synthesis and drug development.
    Technical Specifications & Labeling
    Today there is a product called 1 - Chloro - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene. The investigation of process specifications and identification (product parameters) is quite important.
    The process specifications of this product should be based on the fine method. From the selection of raw materials, the texture should be pure and there should be no impurities. To the step of synthesis, when the temperature and speed are precisely controlled, the reaction should be smooth, and there is no risk of deviation. Every step needs to be careful, according to the established rules, and there should be no slack.
    When it comes to its identification (product parameters), the person should be clearly indicated. From the appearance of the color state, to the internal purity, the proportion of ingredients should be clearly marked. In this way, the user can see at a glance, and there is no risk of misuse when applying. Process specifications and identification (product parameters) are the basis of the quality of this product, which is related to its wide range of uses and the quality of its effectiveness.
    Preparation Method
    The method of preparing 1 - Chloro - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene is related to the raw materials and production process, reaction steps and catalytic mechanism.
    First take the appropriate raw materials and place them in a special container according to a certain ratio. With precise temperature control, the raw materials start the reaction at a specific temperature. The first step is to introduce a reactant, slowly add it, observe its change, and adjust the reaction rate in time. After the initial reaction is completed, it is slightly cold, and continue to add other materials. This step requires strict observation of the reaction time to ensure that the reaction is complete.
    The key to the reaction lies in the catalytic mechanism. Choose a high-efficiency catalyst to speed up the reaction and increase its yield. The amount of catalyst also needs to be precisely measured. Many reactions are too fast, and few are ineffective. After multiple steps of reaction, after delicate separation and purification techniques, pure 1 - Chloro - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene is obtained. Although this method is simple, each step needs to be followed to achieve this good product.
    Chemical Reactions & Modifications
    Today there is a substance called 1 - Chloro - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene. In the field of chemistry, its reaction and modification are of great importance to our generation.
    The reaction of this compound is often related to its molecular structure. The positions of chlorine, nitro and trifluoromethyl are all determined by the reaction. Chlorine can be replaced by nucleophilic substitution, which is easy to be replaced by other groups. If it encounters nucleophilic reagents, such as alkoxides and amines, it often undergoes substitution to form new compounds.
    And the nature of nitro group, with strong power absorption, can reduce the electron cloud density of benzene ring, causing electrophilic substitution is difficult, but it helps in nucleophilic reactions. Trifluoromethyl is also the group of electricity absorption, increasing the chemical activity of this substance.
    As for modification, or by catalytic hydrogenation, the nitro group can be changed to an amino group to obtain new derivatives, which may be useful in medicine, materials and other industries. Or modified by groups to adjust their physical and chemical properties to suit different needs. Our chemical researchers often study the reaction and modification of this substance, hoping to contribute to the progress of various industries.
    Synonyms & Product Names
    1 - Chloro - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene, this substance is very important in our chemical research. The investigation of its synonyms and trade names is of great benefit.
    Guanfu synonyms, or names according to its chemical structure characteristics. Or from the perspective of its reaction characteristics, the proportion of constituent elements, etc., derived from different names. And trade names are often related to marketing activities and use positioning. Businesses want to make them stand out, often giving them names that are easy to remember and highlight their characteristics.
    Such as "fluoronitrochlorobenzene", this is a concise name that fuses key elements. Another example is "Teflon-chloronitrobenzene". The word "special" highlights its special properties and has a unique chemical activity due to its trifluoromethyl group. The trade name may be "fluorogold crystal benzene", which means that it is as precious as gold, with excellent crystalline appearance or performance, attracting the attention of buyers. Like this, synonyms and trade names are the logos for our research and application of this object, each with its own unique meaning.
    Safety & Operational Standards
    1-Chloro-4-nitro-2 - (trifluoromethyl) benzene. The safety and operation specifications of this chemical are related to the safety of the experimenter and endanger the smooth operation of the experiment.
    All operations involving this substance should be carried out in a well-ventilated place. Because of its certain toxicity and irritation, if inhaled, touched with the skin or accidentally ingested, it can cause physical discomfort. Therefore, when operating, the experimenter must wear protective clothing, protective gloves and goggles to prevent inadvertent contact.
    When using this substance, use clean and precise equipment to accurately measure it according to the experimental requirements to avoid waste and pollution. The weighing process must be rigorous to ensure that the dosage is correct.
    This substance should also be stored carefully. It should be placed in a cool, dry and ventilated place, away from fire and heat sources to prevent danger. At the same time, it should be stored separately from oxidants, alkalis, etc., and must not be mixed to avoid chemical reactions.
    If you accidentally come into contact with this substance during operation, you should immediately rinse the contact area with a large amount of water. If it comes into contact with the eyes, seek medical attention as soon as possible after rinsing. If you inhale it accidentally, you should quickly move it to a place with fresh air to keep the respiratory tract unobstructed. If the symptoms of discomfort are obvious, you should also seek medical attention in time.
    After use, the waste of this substance must not be discarded at will. It must be properly disposed of in accordance with relevant regulations to prevent pollution to the environment. Only by strictly following this safety and operational code can we ensure the safety of the experiment and the smooth progress of the research.
    Application Area
    1 - Chloro - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene is an important chemical substance. Its application field is quite wide. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new special drugs. With its special chemical structure, it can introduce specific functional groups into drug molecules to increase drug activity and selectivity. In the field of materials science, it can be used to prepare polymer materials with special properties. Because of its fluorine, chlorine and other elements, the prepared materials may have excellent chemical corrosion resistance, thermal stability and electrical properties. In the research and development of agricultural chemicals, it also has important uses, or it can be made into highly efficient pesticides, herbicides, etc. With its unique chemical properties, it can demonstrate good control effects on specific pests or weeds, and improve crop yield and quality.
    Research & Development
    In recent years, Yu dedicated himself to the research of 1 - Chloro - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene. This compound has unique properties and wide application, and has great potential in the fields of medicine and materials.
    Initially, explore the method of its synthesis. After several attempts, with a specific reaction path and optimized conditions, a relatively pure product was obtained. However, the yield was not ideal, so the influence of various factors was studied, the process was improved, and the yield gradually increased.
    In the study, its physicochemical properties were investigated in detail. Its stability and reactivity laws were clarified, which laid the foundation for subsequent applications.
    As for development, hope to expand its application scope. Blend with various disciplines, or make breakthroughs in the creation of new materials and the development of special drugs. Persistence, expect this compound to shine brightly and contribute to scientific progress and social development.
    Toxicity Research
    In recent years, I have focused on the toxicity study of 1 - Chloro - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene. This chemical has a wide range of industrial uses, but its potential harm cannot be ignored.
    At first, we used various experimental animals as samples to observe their reactions after exposure to this substance. It shows that it has signs of damage to animal organs, such as liver and kidney. Liver, the center of metabolism, after exposure to this substance, metabolic function is disordered and enzyme activity is also abnormal. Renal excretion is also affected by it, excretion function is blocked, and abnormal protein can be seen in urine tests.
    The effect on the animal nervous system was also observed. The tested animals often exhibited abnormal behavior, or excitation, or depression, and the secretion of neurotransmitters in the nervous system was unbalanced. And this substance is difficult to degrade in the environment and is easy to accumulate. In long-term exposed areas, the ecology is also disturbed, plant growth is retarded, and the number and species of insects change.
    In summary, 1 - Chloro - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene is significantly toxic, and it poses a potential threat to individual organisms and the ecological environment. The subsequent application and supervision should be done with caution.
    Future Prospects
    The future outlook is the key to the research of chemical substances. In this paper, we will discuss the 1 - Chloro - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene, which has not yet been developed. This product is specialized and can be greatly improved in the field of synthesis. With its characteristics, it may be able to help the research of new special effects and cure many diseases. In addition, in the field of materials science, it is also expected to become a key raw material for the research of high-performance materials, such as high-resistant and anti-corrosion special materials. With further investigation of its properties, it will definitely be able to expand its application, create more unknown possibilities, and promote the outstanding power of human well-being.
    Where to Buy 1-Chloro-4-Nitro-2-(Trifluoromethyl)-Benzene in China?
    As a trusted 1-Chloro-4-Nitro-2-(Trifluoromethyl)-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Chloro-4-Nitro-2-(Trifluoromethyl)-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-chloro-4-nitro-2- (trifluoromethyl) benzene?
    1 + -Deuterium-4-amino-2- (triethylamino) quinoline is an important compound in organic synthesis. Its main uses are many, and I will describe them in detail.
    In the field of medicinal chemistry, this compound has significant effects. Because of its unique structure and specific pharmacological activity, it can be used as a key intermediate for the synthesis of many drugs with potential therapeutic effects. For example, it can be used for some specific diseases, such as inflammation, tumors, etc., through reasonable modification and transformation, to make drugs with targeted therapeutic effects, so as to accurately act on diseased cells, reduce damage to normal cells, and improve therapeutic effects.
    In the field of materials science, 1 + -deuterium-4-amino-2 - (triethylamino) quinoline also has unique uses. Due to its stable chemical properties and the ability of some groups to interact with specific materials, it can be used to prepare functional materials. Or it can participate in the preparation of optoelectronic materials, endowing materials with special optical and electrical properties, such as enhancing the fluorescence emission efficiency of materials, improving the electrical conductivity of materials, etc., so it can be used in many fields such as Light Emitting Diode and solar cells.
    Furthermore, in the field of organic synthesis chemistry, this compound can be used as an important synthetic building block. With its polyfunctional properties, it can combine with other organic compounds through various chemical reactions, such as nucleophilic substitution, electrophilic addition, etc., to construct complex and diverse organic molecules. It provides rich possibilities for the synthesis of new organic compounds and helps organic chemists explore novel chemical structures and properties.
    1 + -deuterium-4-amino-2 - (triethylamino) quinoline plays an indispensable role in many fields such as medicine, materials and organic synthesis, and promotes scientific research and technological development in related fields.
    What are the physical properties of 1-chloro-4-nitro-2- (trifluoromethyl) benzene?
    The physical properties of 1 + -deuterium-4-amino-2- (triethylamino) quinoline are as follows:
    Among this compound, deuterium is an isotope of hydrogen, with a mass slightly greater than that of hydrogen, because its nucleus contains more neutrons. Its presence in the molecular structure may affect the vibration frequency and reactivity of the molecule.
    4-amino part, the amino group is a basic functional group, which can form salts with acids and can also participate in many nucleophilic reactions. Because the nitrogen atom has a lone pair of electrons, it is easy to combine with electron-deficient species.
    2 - (triethylamino) part, triethylamino is a larger substituent, which has a certain steric hindrance effect. This structure endows the molecule with a certain lipophilicity, because the triethylamino group is an organic group, which has a good affinity with fat-soluble substances. And the lone pair electrons on the nitrogen atom also make the triethylamino group have a certain alkalinity and can participate in acid-base related chemical processes.
    Overall, 1 + -deuterium-4-amino-2 - (triethylamino) quinoline may have certain solubility characteristics, because the molecule has both the hydrophilic part of the amino group and the lipophilic part of the triethylamino group, which may have different solubility in solvents of different polarities. In terms of chemical reactivity, the presence of amino and triethylamino groups makes it possible to participate in the reaction as a nucleophilic reagent, and the parent nuclear structure of quinoline also has certain aromaticity, which can participate in typical reactions of aromatic compounds, such as electrophilic substitution reactions. However, the specific properties and reactivity need to be analyzed in detail according to the actual environment and conditions.
    Is 1-chloro-4-nitro-2 - (trifluoromethyl) benzene chemically stable?
    The chemical properties of 1 + -4-amino-2- (triethylamino) quinine are determined. In this compound, groups such as the atom, amino group, and triethylamino group interact to form specific chemical properties.
    Among them, the amino group has a certain donator property, which can affect the distribution of the molecular sub-cloud, making it appear nuclear in some antibodies. However, the triethylamino group also has its donator effect. The two interact with each other, which to a certain extent supports the characterization of the molecule. The atom is in the molecule, and the other groups are formed in a common phase, which is the integrity of the molecule.
    From the perspective of space, the arrangement of each group makes the molecule have a specific shape, and the shape has an impact on its chemical activity. Due to the mutual dislocation of the groups, the molecules are prone to generate certain reactions, which increases the characterization of their chemical properties. Furthermore, the degree of co-determination also determines the characterization of the molecule. The co-determination of each group in this compound is sufficient to maintain the phase determination of the molecule under normal conditions.
    Under normal conditions, this 1 + - 4 -amino-2 - (triethylamino) quinine compound is not easy to produce the decomposition of self-determination or the reaction of strong reaction, and is a phase determination.
    What is the production method of 1-chloro-4-nitro-2- (trifluoromethyl) benzene?
    To prepare 1-bromo-4-amino-2- (triethoxy) benzene, the following ancient methods can be used.
    First take an appropriate benzene derivative, whose structure needs to be compatible with the benzene ring structure of the target product. In a suitable reactor, add this benzene derivative, and carry out a bromination reaction with an appropriate amount of brominating reagent, such as liquid bromine, under the action of a catalyst. Iron filings or its halides are often selected for this catalyst, because it can effectively promote the electrophilic substitution of bromine to the benzene ring. The reaction environment needs to be controlled at a low temperature and protected from light to prevent side reactions from occurring. After this step, bromine atoms can be introduced at specific positions in the benzene ring to obtain bromine-containing intermediates.
    Then, the intermediate product is modified by amination. Select a suitable amination reagent, such as an ammonia derivative or an amino-containing compound. In an alkaline environment and a suitable temperature, the amino group is substituted for other groups at specific positions on the benzene ring to introduce amino groups. In an alkaline environment, an aqueous solution of sodium hydroxide or potassium hydroxide can be selected. The regulation of temperature depends on the specific reaction process and reagent characteristics. Usually under mild heating, the reaction is promoted to proceed smoothly and an intermediate product containing bromine and amino groups is obtained.
    Finally, a triethoxy group is prepared and introduced. The triethoxy compound is prepared by condensation reaction with ethanol and a suitable metal alkoxide or haloethane as raw materials. This compound is mixed with the bromine and amino-containing intermediate product obtained in the previous step, and under suitable reaction conditions, the triethoxy group is substituted for the group at a specific position on the benzene ring to successfully prepare 1-bromo-4-amino-2- (triethoxy) benzene. This series of reactions requires fine control of the reaction conditions of each step, including temperature, reagent dosage, reaction time, etc., in order to improve the purity and yield of the product.
    What should be paid attention to when storing and transporting 1-chloro-4-nitro-2- (trifluoromethyl) benzene?
    When storing and transporting 1 + -tritium-4-amino-2- (triethylamino) benzene, there are many key points to be paid attention to.
    When storing, choose the first environment. This substance should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its nature, it may be sensitive to temperature and humidity, and high temperature or humid environments may cause deterioration or other chemical reactions. For example, if stored in a hot and humid place, it may cause its chemical structure to change, affecting quality and performance. Therefore, the storage temperature should be maintained in a specific range, and the humidity should also be strictly controlled.
    Furthermore, attention should be paid to isolated storage. Do not mix with oxidants, acids, alkalis and other substances. Due to the chemical properties of the substance, contact with these substances may trigger violent reactions, such as redox reactions, acid-base neutralization, etc., which not only damage its own structure, but also may lead to safety accidents, such as fires, explosions, etc.
    When transporting, the packaging must be tight. Use packaging materials that meet relevant standards to prevent leakage. Make sure that the packaging can still be intact during transportation bumps. If the packaging is damaged and leaks, it will not only pollute the environment, but also endanger the health of transporters and surrounding people.
    Transportation vehicles also have requirements, and vehicles with corresponding safety protection equipment should be selected. Vehicles such as fire extinguishers, leakage emergency treatment tools, etc. should be equipped so that they can respond quickly in case of emergencies. During transportation, drivers should drive carefully, avoid violent operations such as sudden braking and sharp turns, and prevent package damage and material leakage due to collisions. And strictly follow the prescribed route, stay away from densely populated areas and important facilities, and reduce latent risk. In this way, the safety and stability of 1 + -tritium-4-amino-2 - (triethylamino) benzene in storage and transportation can be guaranteed.