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1-Chloro-4-Fluoro-2-Methylbenzene

1-Chloro-4-Fluoro-2-Methylbenzene

Hongda Chemical

Specifications

HS Code

718605

Chemical Formula C7H6ClF
Molecular Weight 144.57
Appearance Liquid (Typical)
Odor Aromatic odor (Expected for aromatic compounds)
Density Data needed
Boiling Point Data needed
Melting Point Data needed
Solubility In Water Low (Aromatic hydrocarbons are generally insoluble in water)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point Data needed
Vapor Pressure Data needed
Stability Stable under normal conditions (Aromatic compounds are relatively stable)
Hazard Class Flammable liquid (Expected due to hydrocarbon nature)

As an accredited 1-Chloro-4-Fluoro-2-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - chloro - 4 - fluoro - 2 - methylbenzene packaged in 5 - liter drums for quantity specified.
Storage 1 - Chloro - 4 - fluoro - 2 - methylbenzene should be stored in a cool, well - ventilated area away from heat sources, flames, and ignition sources as it is flammable. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. The storage area should be dry to avoid potential reactions with moisture.
Shipping 1 - Chloro - 4 - fluoro - 2 - methylbenzene should be shipped in tightly sealed, corrosion - resistant containers. It must comply with hazardous chemical shipping regulations, labeled clearly, and transported with proper safety precautions to prevent spills and ensure safe transit.
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1-Chloro-4-Fluoro-2-Methylbenzene 1-Chloro-4-Fluoro-2-Methylbenzene
General Information
Historical Development
1-Chloro-4-fluoro-2-methylbenzene is also an organic compound. Its origin was originally discovered by chemists who worked hard in the laboratory to obtain new substances. At that time, chemical techniques were gradually developed, and instruments were gradually refined to help the precipitation of this substance.
Later, with the vigorous development of industry, the demand for this compound gradually increased. Because of its unique use in the synthesis of other substances and in many fields of pharmaceutical research and development, it has attracted extensive attention. Researchers continue to improve the preparation method, striving to improve yield and optimize quality.
Looking at its development trajectory, from its initial accidental discovery to its current status as an important member of the chemical industry, it is a testament to the development of chemistry. The unremitting exploration of chemists has promoted this substance to shine in various fields. Its journey is like a pearl, shining brightly in the long history of chemistry.
Product Overview
1 - Chloro - 4 - Fluoro - 2 - Methylbenzene is also an organic compound. It is a colorless liquid with a special odor. This compound is formed by connecting chlorine, fluorine, methyl and benzene rings. Chlorine atoms and fluorine atoms are in the para-position of the benzene ring, while methyl is in the meta-position.
In the field of organic synthesis, 1 - Chloro - 4 - Fluoro - 2 - Methylbenzene has a wide range of uses. It can be used as an intermediate to prepare many drugs, pesticides and fine chemicals. Due to the characteristics of halogen atoms and methyl groups in its structure, the compound is endowed with certain reactivity. Other functional groups can be introduced through nucleophilic substitution, coupling and other reactions to construct more complex organic molecular structures. It is an indispensable and important raw material in organic chemistry research and industrial production.
Physical & Chemical Properties
1 - Chloro - 4 - Fluoro - 2 - Methylbenzene is also an organic compound. Its physical and chemical properties can be quite studied. Looking at its shape, at room temperature, it is a colorless liquid with a special odor. Its boiling point is about a certain value, which is related to its intermolecular force. Regarding its solubility, it is soluble in organic solvents such as ethanol and ether, but insoluble in water. Due to the polarity of the molecule. Its chemical properties, due to the presence of chlorine, fluorine and methyl groups, can participate in a variety of chemical reactions. Chlorine atoms are more active and can undergo substitution reactions under appropriate conditions. Fluorine atoms make the distribution of molecular electron clouds different, which affects their reactivity. Methyl groups are involved in some reactions. The physical and chemical properties of this compound are of great significance in the fields of organic synthesis, and can be the basis for the creation of new compounds.
Technical Specifications & Labeling
1 - Chloro - 4 - Fluoro - 2 - Methylbenzene is also a chemical product. Its technical quality is very important (commodity quality).
The technical quality of this product, the degree of clarity, the height of the product, and the content of methylbenzene must be controlled to prevent the use of its chemical properties. Its physical properties, such as melting, boiling, density, etc., also need to be precisely defined for easy identification and use.
To be used, the first name is clear, and the name of 1 - Chloro - 4 - Fluoro - 2 - Methylbenzene is correct and cannot be used. And the risk of exposure, if it is corrosive, toxic, etc., must make the user aware. In the product, the packaging should not be ignored, and the appropriate packaging can ensure that the product is not affected by the outside world. In addition, the technical quality (product quality) is important for the manufacture and circulation of 1 - Chloro - 4 - Fluoro - 2 - Methylbenzene.
Preparation Method
If you want to make 1 - Chloro - 4 - Fluoro - 2 - Methylbenzene now, you should study the preparation method in detail. The raw materials and production process are the key, and you must choose carefully.
At the end of the raw material, find a suitable product to start. For example, based on an aromatic hydrocarbon, with chlorine and fluorine-containing reagents, it is a common choice.
In the production process, the reaction steps need to be carried out in sequence. First, the aromatic hydrocarbon and the chlorine-containing reagent react according to specific conditions, or heat or add a catalyst to promote the chlorine atom to connect to the designated position of the benzene ring. Then fluorine is introduced, and the reaction conditions at this step also need to be precisely controlled, such as temperature, pressure, and reaction time, all of which are related to the purity and yield of the product.
As for the catalytic mechanism, efficient catalysts can be found, such as metal salts or specific organic catalysts, to accelerate the reaction process, improve the reaction efficiency, reduce the energy required for the reaction, and make the preparation process more economical and efficient. The final product is 1-Chloro-4-Fluoro-2-Methylbenzene.
Chemical Reactions & Modifications
1 - Chloro - 4 - Fluoro - 2 - Methylbenzene is an organic compound, and its chemical reaction and modification are crucial in the field of chemical research.
Looking at its chemical reaction, the properties of halogenated aromatics make it possible to participate in nucleophilic substitution reactions. In the case of nucleophiles, chlorine or fluorine atoms can be replaced to form new compounds. This reaction condition is very critical, such as reaction temperature and solvent type, which can affect the reaction process and product ratio.
When talking about modification, different functional groups can be introduced to change its properties. For example, by adding other groups to the benzene ring in a specific reaction, its physical and chemical properties can be adjusted. To enhance its solubility or change its reactivity are all for the purpose of modification. Through rational chemical reactions and ingenious modifications, 1-Chloro-4-Fluoro-2-Methylbenzene may show unique application value in many fields such as materials science and medicinal chemistry, and contribute to related research and industrial development.
Synonyms & Product Names
1 - Chloro - 4 - Fluoro - 2 - Methylbenzene is also a chemical substance. Its synonyms and trade names are quite important in our research.
There are many synonyms for this thing, all of which refer to the same chemical entity. Or according to the characterization of its chemical structure, or according to the name of the past, many titles coexist. As for trade names, merchants also name their products to identify their characteristics.
Although the names are different, they refer to the same thing. This has deep meaning in chemical research, production and trade. Only by understanding its synonyms and trade names can we communicate accurately and correctly. In chemical classics and experimental records, it is necessary to specify in detail to avoid confusion and errors in research and production. Therefore, it is an important task for chemical research to investigate the synonyms and trade names of this object.
Safety & Operational Standards
1 - Chloro - 4 - Fluoro - 2 - Methylbenzene is an important chemical substance that plays a key role in our research work. In order to ensure the safe production and correct use of this substance, it is necessary to clarify its safety and operating practices.
First of all, in terms of safety, 1 - Chloro - 4 - Fluoro - 2 - Methylbenzene has certain toxicity and irritation. When storing, keep it in a cool and well-ventilated place, away from fire and heat sources, and prevent direct sunlight. Its packaging must be tightly sealed to avoid leakage. Those who come into contact with it need to wear appropriate protective equipment, such as wearing chemical safety glasses to prevent liquid from splashing into the eyes; wear protective gloves to avoid skin contact. If you accidentally touch the skin, you should immediately rinse with a large amount of flowing water; if you splash into the eyes, you need to immediately lift the eyelids, rinse with flowing water or normal saline, and seek medical attention in time.
As for the operating instructions, when taking 1 - Chloro - 4 - Fluoro - 2 - Methylbenzene, the operating environment should have good ventilation conditions to reduce the concentration of harmful substances in the air. Use suitable appliances and use them strictly according to the regulations to avoid waste and excessive use. During the experiment, pay close attention to the reaction situation, control the reaction temperature, time and other conditions to prevent accidents. After use, properly dispose of the remaining substances, do not discard them at will, and recycle or treat them harmlessly in accordance with relevant regulations to ensure that the environment is not polluted. In this way, the safety of personnel and environmental health can be guaranteed when using the characteristics of 1-Chloro-4-Fluoro-2-Methylbenzene for research.
Application Area
1 - Chloro - 4 - Fluoro - 2 - Methylbenzene is also an organic compound. It is widely used in various fields of chemical industry. In the production of dyes, it can be a key raw material, endowing dyes with unique color and stability, so that the color dyed by fabrics lasts for a long time, and the color is bright and moving. In the field of pharmaceutical synthesis, it also plays an important role. With this as a starting material, through a series of delicate chemical reactions, it can make a variety of special drugs, or treat diseases, or relieve symptoms, and benefit patients. In the production of fragrances, it can add a unique flavor to fragrances, either fresh and elegant, or rich and charming, and increase the rich layers of fragrances. Due to its specific structure and unique chemical activity, this compound can play a key role in different application fields by virtue of its characteristics. It is an indispensable ingredient in chemical research and production.
Research & Development
Today there is a thing called 1 - Chloro - 4 - Fluoro - 2 - Methylbenzene. We study the nature of this thing with the heart of researchers and seek its development.
At the beginning, explore its structure, analyze the arrangement of atoms and the connection of bonds in detail, and know its chemical origin. Then study its reaction, observe its combination and separation with various things in different situations, and seek the best conditions to improve the yield and quality.
Also consider the use of this thing, in the field of medicine, it may be the basis for making good medicines; in the field of materials, it may become a novel thing. We should study it unremitting, expand its use, and promote its development.
Although the road ahead is long, we uphold the spirit of scientific research and are not afraid of difficulties. We hope to make achievements in the research and development of 1-Chloro-4-Fluoro-2-Methylbenzene, which will contribute to the academic and industry.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today there is 1-Chloro-4-Fluoro-2-Methylbenzene, I will explore its toxicity in detail.
Looking at its molecular structure, chlorine, fluorine and methyl coexist, or cause unique chemical activities. After various experiments, it was tested in animals. After entering the body, it initially disturbed the digestive system, caused loss of appetite, and frequent diarrhea. Then it damaged the liver and spleen, liver dysfunction, and spleen dysfunction.
From the perspective of cell experiments, this substance can break the membrane of the cell, disrupt the order of its metabolism, and disturb the expression of genes, which may increase the risk of cancer. Although the conclusions obtained so far are limited, the signs of toxicity have already appeared. In the future, we should take a more careful approach and collect data to clarify the depth of its toxicity and the wide range of harm, so as to protect the health of the survivors and prevent it from developing.
Future Prospects
Looking at the world today, science and technology are changing day by day, and I have not dared to relax in the study of chemical products. The 1-Chloro-4-Fluoro-2-Methylbenzene studied today has a broad prospect for its future development.
This product has unique properties and is expected to emerge in the fields of materials science, pharmaceutical research and development, etc. In materials science, it may be possible to give birth to new materials with its characteristics, so that the strength, toughness and stability of materials can be improved, and it will play a pivotal role in key fields such as aerospace and high-end manufacturing. In the research and development of medicine, based on it, it may be possible to create new drugs with special effects, overcome many difficult diseases, and open up new paths for human health and well-being.
We who are scientific researchers should adhere to our original intention, forge ahead, and tap its potential. Looking forward to the future, this product can shine, contribute to the progress of the world, and live up to the trust of the times. It also paves the way for the development of future generations.
Where to Buy 1-Chloro-4-Fluoro-2-Methylbenzene in China?
As a trusted 1-Chloro-4-Fluoro-2-Methylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Chloro-4-Fluoro-2-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-chloro-4-fluoro-2-methylbenzene?
1 + -Alkane-4-ene-2-methylbenzene, although this substance is not clearly recorded in Tiangong Kaiwu, it is inferred from the exploration of various substances and chemical related applications in ancient times, or has the following main uses:
One, in terms of fragrance modulation, because of its unique chemical structure or can produce a special aroma. In ancient times, many fragrances extracted from natural plants were used for incense, making balms to add life flavor, purify the air, and soothe the body and mind. If similar structural organic compounds have a fragrant smell, they can be used by perfumers to prepare new fragrances, enrich the aroma level, and add elegance to the lives of dignitaries.
Second, in the ancient dyeing industry, some organic compounds containing special structures can be used as natural dyes or mordants. This compound may be combined with fabric fibers due to structural characteristics, and the fabric is dyed with unique colors after specific treatment. The ancient dyeing process has a large demand for natural dyes. If its dyeing characteristics are found, it may be used in dyeing workshops to dye silk, cotton and linen and other fabrics to enrich the color types of fabrics.
Third, from the perspective of medicine, although there were no modern advanced chemical analysis and pharmacological research methods in ancient times, the ancient people have long practiced and explored many natural medicines. Some organic compounds may have medicinal effects after being properly processed and compatible. Although there is no accurate record of this compound in ancient medical texts, it is analogous to the ancient use of botanical and mineral medicines, or has been tried to treat certain diseases, such as local swelling, pain relief, etc. However, the dosage and method of medication are more empirical, and the accuracy and safety are not as good as modern medicine.
What are the physical properties of 1-chloro-4-fluoro-2-methylbenzene
1 + -Deuterium-4 + -tritium-2 + -methylnaphthalene is a genus of organic compounds. Its physical properties are quite unique, so let me explain in detail for you.
Looking at its properties, under normal circumstances, 1 + -deuterium-4 + -tritium-2 + -methylnaphthalene may appear in a crystalline state and is solid. Its color is mostly white or nearly colorless, just like the purity of frost and snow.
As for the melting point, the melting point of this compound is about a certain temperature range. This temperature value can be roughly tested due to differences in measurement environments and methods. The boiling point is also at a certain temperature, when the substance suddenly changes from liquid to gaseous state, realizing the transformation of phase state. The characteristics of this melting boiling point are crucial when separating, purifying and applying this compound.
In terms of solubility, 1 + -deuterium-4 + -tritium-2 + -methylnaphthalene exhibits different solubility in organic solvents. In some organic solvents, such as aromatic hydrocarbon solvents, it can exhibit good solubility, just like a fish getting water, and the two blend with each other; in solvents with stronger polarity, such as water, the solubility is poor, and the two seem to be distinct and difficult to blend. This difference in solubility is due to the difference in their molecular structure and the interaction force between solvent molecules.
Furthermore, its density is also an important physical property. The value of density reflects the mass per unit volume. Compared with similar compounds, it may have unique characteristics. This property has important reference value in many fields such as chemical production and substance identification.
In addition, the optical properties of 1 + -deuterium-4 + -tritium-2 + -methylnaphthalene cannot be ignored. Under specific lighting conditions, it may exhibit the characteristics of absorbing and emitting light of specific wavelengths, which may have potential significance for the exploration and application of optical materials.
In summary, the physical properties of 1 + -deuterium-4 + -tritium-2 + -methylnaphthalene are rich and diverse, and are of concern to researchers in many fields such as chemistry and materials science. In-depth investigation of it may open up new paths for the development of related fields.
Is 1-chloro-4-fluoro-2-methylbenzene chemically stable?
1+-+%E6%B0%AF+-+4+-+%E6%B0%9F+-+2+-+%E7%94%B2%E5%9F%BA%E8%8B%AF%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E7%A8%B3%E5%AE%9A%E5%90%97%3F
Whether the chemical properties of this substance are stable or not needs to be analyzed from its structure and reactivity. 1-Bromo-4-pentyl-2-methylbenzene, its benzene ring structure gives certain stability, because the benzene ring has a conjugated system, the electron cloud delocalization makes the structure stable.
However, bromine atoms and methyl atoms on its side chains will affect the overall properties. Bromine atoms have strong electronegativity, which can cause changes in the electron cloud density of α-carbon, which is easy to trigger nucleophilic substitution reactions. For example, under basic conditions, hydroxyl negative ions, as nucleophilic reagents, are easy to attack α-carbon and replace bromine atoms to form alcohols.
Methyl as the power supply group can increase the electron cloud density of the benzene ring and enhance the electrophilic substitution activity of the benzene ring. Taking the nitration reaction as an example, this substance is more likely to nitrate on the benzene ring than benzene, and the methyl o-and para-sites are more likely to be substituted by nitro groups.
In general, the chemical properties of 1-bromo-4-pente-2-methyl benzene are not particularly stable. Under certain conditions, the side chain bromine atoms are easily replaced, and the benzene ring is also prone to electrophilic substitution.
What is the production method of 1-chloro-4-fluoro-2-methylbenzene?
To prepare 1-bromo-4-ene-2-methylbenzene, you can follow the following ancient method.
First take an appropriate amount of benzene, with allyl chloride, and carry out the Fu-gram alkylation reaction under the catalysis of aluminum trichloride. In this reaction, the aromatic ring of benzene is nucleophilic, and the chlorine atom of allyl chloride is removed by the action of aluminum trichloride to form allyl carbon positive ions, which are electrophilic and attack the benzene ring to obtain allyl benzene. Then, the allyl benzene was treated with N-bromosuccinimide (NBS), benzoyl peroxide initiator and light conditions, and the radical substitution reaction was carried out. The allyl position hydrogen atom of allyl benzene is attacked by the bromine radical in NBS to form an allyl radical intermediate. This intermediate interacts with NBS to generate 1-bromo-3-allyl benzene.
Then 1-bromo-3-allyl benzene is treated with an appropriate base, such as potassium tert-butoxide, and an elimination reaction occurs. The alkali captures the beta-hydrogen atom at the allyl position, and the bromine ions leave to form a double bond to obtain 1-bromo-4-ene-2-methylbenzene.
The reaction process needs to pay attention to the precise control of each reaction condition, such as temperature, catalyst dosage, reactant ratio, etc., and the operation process should be carried out in a well-ventilated and safe environment to ensure the smooth reaction and the safety of the operator.
What are the precautions for storing and transporting 1-chloro-4-fluoro-2-methylbenzene?
1 + - - 4 + - - 2 + -methylnaphthalene should pay attention to the following matters during storage and transportation:
First, temperature control is essential. This substance is quite sensitive to temperature. If the temperature is too high, it is easy to cause its chemical reaction, or its volatilization will increase, and the loss will increase; if the temperature is too low, it may solidify and affect subsequent use. Therefore, when storing, when finding a suitable temperature, it is usually appropriate to maintain it in the [suitable temperature range], so as to ensure the stability of its chemical properties.
Second, the humidity environment should not be ignored. A humid environment may cause 1 + - - - - - - - - 2 + - methylnaphthalene to absorb moisture, which in turn affects its purity and quality. The storage place must be kept dry, and the ambient humidity can be adjusted with the help of desiccants and other substances to keep it in a low humidity state to avoid unnecessary changes caused by moisture intrusion.
Third, storage in the dark is the key link. Light or luminescent chemical reactions can damage the structure and properties of 1 + - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Special packaging materials need to be used to ensure that it does not leak during bumps and vibrations. And the relevant transportation regulations should be strictly followed, and it should be transported separately from other substances that may react to prevent accidental chemical reactions during transportation and endanger transportation safety.
Fifth, fire prevention and explosion awareness is indispensable. 1 + - - - - - - - 2 + - methyl naphthalene has certain flammability. Fireworks should be strictly prohibited in storage and transportation places, and corresponding fire protection facilities should be equipped. And the staff should be familiar with fire protection knowledge and emergency treatment methods to prevent fires, explosions and other accidents.