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1-Chloro-3-Nitro-5-(Trifluoromethyl)Benzene

1-Chloro-3-Nitro-5-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    468436

    Chemical Formula C7H3ClF3NO2
    Appearance Typically a colorless to light - colored liquid or solid
    Boiling Point Specific value depends on purity and conditions, but generally in a certain range related to its molecular structure
    Melting Point Also specific to purity, but has a characteristic melting range
    Density Density value is related to its molecular packing and temperature
    Solubility Solubility characteristics vary in different solvents such as organic solvents like ethanol, acetone etc.
    Vapor Pressure Vapor pressure is related to temperature and volatility
    Flash Point Indicates the flammability risk under certain conditions
    Stability Stability can be affected by heat, light, and certain chemical substances

    As an accredited 1-Chloro-3-Nitro-5-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1 - chloro - 3 - nitro - 5 - (trifluoromethyl)benzene, 500g, packed in air - tight glass bottle.
    Storage 1 - Chloro - 3 - nitro - 5 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials. Label the storage container clearly to avoid misidentification.
    Shipping 1 - Chloro - 3 - nitro - 5 - (trifluoromethyl)benzene is a chemical. Shipping should be in accordance with hazardous material regulations. Use proper packaging to prevent leaks and ensure safe transportation via approved carriers.
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    1-Chloro-3-Nitro-5-(Trifluoromethyl)Benzene 1-Chloro-3-Nitro-5-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene is an important chemical product. Tracing its historical development, early chemical research was still unknown, and such compounds were not yet well known to the world. As time went by, chemical technology advanced, and researchers gradually explored its field.
    At the beginning, the understanding of its structure and properties was like seeing flowers in the fog, blurred. However, many chemists were reluctant to study it, and after countless experiments, they began to get a glimpse of its mysteries. From the initial simple experimental equipment to today's sophisticated instruments, the study of 1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene has been deepened step by step.
    Its synthesis method has also been continuously improved, from the initial inefficient and poor purity production method to today's efficient and precise process. This compound has emerged in many fields, and its historical development has witnessed the vigorous progress of chemical science, just like the stars shining in the chemical sky.
    Product Overview
    1-Chloro-3-nitro-5- (trifluoromethyl) benzene is also an organic compound. Its color may be light yellow, like a liquid, with a special odor. This compound has a wide range of uses in the chemical industry and is often the key raw material for the synthesis of a variety of fine chemicals.
    The preparation method, or through a specific chemical reaction path, with suitable reactants, can only be obtained by controlling precise reaction conditions, such as temperature, pressure, and catalyst. However, during the preparation process, many factors need to be paid attention to to to ensure the purity and yield of the product.
    Its chemical properties are active, and due to the functional groups such as chlorine, nitro and trifluoromethyl in the molecule, it can participate in a variety of chemical reactions, such as nucleophilic substitution and reduction reactions.
    In industrial applications, due to its unique structure and properties, it can be used to create pesticides, medicines, materials and other products, making great contributions to the development of related industries.
    Physical & Chemical Properties
    1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene is an organic compound. Its physical properties are liquid at room temperature, transparent in color and have a special odor. Its density is heavier than that of water, and it sinks when placed in water. The boiling point is considerable and has a certain volatility.
    In terms of its chemical properties, the chlorine atom is considerable and can participate in the substitution reaction under specific conditions. The presence of nitro groups makes it oxidizing, and a reduction reaction can occur in case of appropriate reducing agents. The properties of trifluoromethyl give the compound unique stability and chemical activity. Due to the coexistence of polyfunctional groups in its structure, it is often a key raw material in the field of organic synthesis and can be converted into a variety of organic products through ingenious reaction paths. It has important application value in the pharmaceutical, pesticide and other industries.
    Technical Specifications & Labeling
    Technical specifications and labeling of 1-chloro-3-nitro-5- (trifluoromethyl) benzene (commodity parameters)
    If you want to make 1-chloro-3-nitro-5- (trifluoromethyl) benzene, the method should be based on precise technical specifications. The selection of materials must be pure and free of impurities, and the materials used should be compatible in appropriate proportions according to their characteristics. The reactor should be resistant to corrosion and heat to meet the needs of the reaction.
    When reacting, control the temperature to a suitable degree, and do not fluctuate between high and low, causing the reaction to be disordered. Stirring should also be uniform and fast, so that the materials are fully blended. And the reaction time also needs to be accurately grasped. If it is too long, it will be too long, and if it is short, it will not be complete.
    As for the label, when stating its name "1-chloro-3-nitro-5- (trifluoromethyl) benzene", list its key parameters, such as purity geometry, impurities, and physical and chemical properties. On the packaging, warning labels are indispensable to inform everyone that its nature is at risk and need to be properly disposed of. In this way, only 1-chloro-3-nitro-5- (trifluoromethyl) benzene products that meet the specifications can be used for needs.
    Preparation Method
    1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene is an important chemical product. The preparation method is the key to the selection of raw materials. A specific benzene series can be selected as the starting material and made by an exquisite synthesis process.
    In the first step, the benzene series needs to undergo a halogenation reaction under specific reaction conditions to introduce chlorine atoms. This process requires precise control of the reaction temperature and the proportion of reactants to make the reaction proceed smoothly.
    In the second step, a nitrification reaction is applied to introduce nitro groups. During this period, the pH of the reaction environment and the reaction time are strictly required.
    Furthermore, through special chemical means, trifluoromethyl is introduced. This step is related to the purity and yield of the product, and attention should be paid to the selection and dosage of the catalyst.
    After each step of the reaction, fine separation and purification are required to remove impurities. In this way, high purity 1-Chloro-3-Nitro-5- (Trifluoromethyl) Benzene can be obtained. During the preparation, attention should be paid to the safety and environmental protection of the reaction to achieve the purpose of efficient and green preparation.
    Chemical Reactions & Modifications
    The chemical reaction and variation of 1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene are of great importance to us.
    To make this product, benzene derivatives are often used as the starting point, and various reactions are chlorination, nitration, and trifluoromethylation. However, the control of conditions is crucial during all reactions. During chlorination, the amount of chlorine, the temperature and duration of the reaction all affect the yield and purity of the product. The nitrification reaction, the strength of the acid, and the environment of the reaction also affect the process.
    As for the mutability, the positions of chlorine, nitro and trifluoromethyl in its structure make this substance have unique chemical activity. Nitro has strong electron-absorbing properties, which can reduce the density of electron clouds of benzene rings, making it difficult to electrophilic substitution reactions; while trifluoromethyl is also an electron-absorbing group, and the two cooperate to change its chemical properties. This substance can be a key intermediate in the field of organic synthesis. After various reactions, a variety of useful compounds can be produced. Therefore, further study of its reaction and modification is of great benefit to the chemical industry.
    Synonyms & Product Names
    1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene, this substance is also an important object of chemical research. Its heteronym and trade name are also subject to our detailed investigation.
    Those with heteronym have different names due to the characteristics of their chemical structure. Due to the order and combination of chlorine, nitro, and trifluoromethyl in the molecule, chemists follow the rules and may have different names.
    As for the trade name, merchants vary according to their use, quality, and market positioning. Or highlight its high purity, called "pure 1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene"; or emphasize its application field, such as "dedicated to a certain field 1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene".
    Detailed investigation of its aliases and trade names is of great significance to our chemical research and production applications. It can help us understand the reference of this thing in different situations, avoid the risk of confusion, and facilitate communication.
    Safety & Operational Standards
    1-Chloro-3-nitro-5- (trifluoromethyl) benzene is also a chemical product. It is related to safety and operating standards and cannot be ignored.
    This substance is dangerous to a certain extent and is related to safety. It should be stored in a cool, dry and well-ventilated place, away from fires and heat sources. If exposed to high temperature or open flames, there is a risk of accidents. The storage place should be separated from oxidizing agents, reducing agents, alkalis, etc., and should not be mixed to prevent violent chemical reactions.
    As for the operation, be sure to abide by the norms. Operators should wear suitable protective clothing, protective gloves and goggles. In the place of operation, good ventilation is required to remove harmful volatile gases. When taking it, the action should be slow to avoid spillage. If it is accidentally spilled, do not panic, and clean it up quickly according to the established method. A small amount of spillage can be swept into a clean, covered container; if there is a large amount of spillage, it is necessary to build a dike or dig a pit for containment, and transfer it to a tanker or a special collector for recycling or transportation to a waste treatment site for disposal.
    Furthermore, the operation room should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. Operators should also be professionally trained, familiar with the properties of this product, and aware of its safety and operation before they can act. In case of accidental contact with skin or eyes, rinse with plenty of water immediately and seek medical attention if necessary.
    In short, the safety and operating practices of 1-chloro-3-nitro-5 - (trifluoromethyl) benzene are the key to ensuring personal safety, environmental safety and production stability.
    Application Area
    1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene is a unique chemical substance with a key application field. In the field of pharmaceutical research and development, it can be used as a key intermediate to help synthesize compounds with specific pharmacological activities, or to create drugs for specific diseases. In the field of materials science, because of its unique chemical structure, it may endow materials with novel properties, such as improved material stability and corrosion resistance. In the preparation of pesticides, it may also play an important role in the development of efficient and low-toxicity pesticides to protect crop growth and resist pest infestation. This compound has a wide range of application fields, and it cannot be ignored in chemical research and industrial production. It is of great significance to promote the development of many fields.
    Research & Development
    1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene is an important chemical substance. In our research and development, we have put a lot of effort into its properties and applications.
    This compound has a unique structure and contains functional groups such as chlorine, nitro and trifluoromethyl. After repeated experiments, it is clear that the delicate balance of its reactivity and stability. It can be used as a key intermediate in the field of organic synthesis.
    In order to expand its application, we have studied different reaction conditions to improve the yield and selectivity. Although many problems were encountered on the way, through unremitting efforts, we gradually gained results. In the future, we will continue to explore its potential, aiming to achieve new breakthroughs in materials science, drug research and development, and contribute to the development of chemistry.
    Toxicity Research
    1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene is also a chemical substance. As a chemical researcher, I explore its toxicity, which is of great significance.
    Looking at this substance, its molecular structure is unique, chlorine, nitro and trifluoromethyl coexist. In toxicity studies, it is necessary to observe its effect on organisms. After experiments, small animals were used as samples and administered this substance. After ingestion, the physiological state gradually changed. Slow movement, reduced food intake, and even physical disorders.
    It can be seen that 1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene has certain toxicity. It may interfere with the normal biochemical reactions in organisms and damage the function of cells. This toxicity study can provide a key basis for industrial production, environmental monitoring and biosafety protection to avoid its harm to life and the environment.
    Future Prospects
    I look at 1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene, which has emerged in the current chemical industry. Although its current application is still limited to some specific fields, I look forward to the future, and its development scene is really full of expectations.
    Due to the advance of science and technology, the unique properties of this compound will surely attract the attention of researchers, and then dig deeper into its potential. Or in the creation of new materials, as a key raw material; or in the development of specific drugs, as a strong cornerstone.
    And the rise of the chemical industry, the demand for raw materials is endless. 1 - Chloro - 3 - Nitro - 5 - (Trifluoromethyl) Benzene, with its characteristics, is expected to shine in the future, in a wider field. I am convinced that with time, it will be able to break through the current limitations, create a new situation for the chemical industry, and achieve extraordinary achievements to meet the endless needs of the future.
    Where to Buy 1-Chloro-3-Nitro-5-(Trifluoromethyl)Benzene in China?
    As a trusted 1-Chloro-3-Nitro-5-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Chloro-3-Nitro-5-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-chloro-3-nitro-5- (trifluoromethyl) benzene?
    1 + -Deuterium-3 + -amino-5- (trifluoromethyl) pyridine has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to create a variety of specific drugs. For example, in the synthesis process of some new antidepressants, it can precisely combine with other compounds by virtue of its unique chemical structure, thus building a molecular structure with specific pharmacological activities, helping to improve the affinity and selectivity of drugs to targets and enhance antidepressant efficacy.
    In the field of pesticide chemistry, it is also an important raw material. Based on it, highly efficient and low-toxic pesticide products can be developed. For example, some new pesticides, with the help of their special properties, can effectively kill specific pests, while minimizing the harm to the environment and non-target organisms, which is in line with the current green and environmentally friendly agricultural development concept.
    In terms of materials science, it can participate in the preparation of functional materials. Like some materials with special optical or electrical properties, the introduction of this substance during synthesis can optimize the performance indicators of materials and expand the application range of materials in optical devices, electronic components and other fields. Because of its indispensable role in many fields, it has attracted much attention and attention in chemical synthesis and other industries, contributing to the promotion of technological innovation and development in related fields.
    What are the physical properties of 1-chloro-3-nitro-5- (trifluoromethyl) benzene?
    The physical properties of 1 + -tritium-3 + -amino-5- (triethylamino) quinine are as follows:
    Under normal temperature and pressure, the state of this substance is either a solid or a viscous liquid, depending on its intermolecular forces and molecular structure. Looking at its appearance, it may be colorless and transparent, or have a slight yellowish color, which is affected by factors such as intramolecular electron transitions and conjugate systems.
    The melting point is discussed, which depends on the strength of intermolecular interactions and the degree of regular molecular arrangement. If there are hydrogen bonds between molecules, strong van der Waals forces, and orderly arrangement, the melting point is higher; otherwise, it is lower. Due to the existence of polar groups such as amino and triethylamino, or the formation of intermolecular hydrogen bonds, the melting point increases.
    The boiling point is also closely related to the intermolecular force. Polar groups enhance the intermolecular force. To transform it from liquid to gas, it needs to supply more energy, so the boiling point may be higher.
    In terms of solubility, because it contains polar groups such as amino and triethylamino, it may have a certain solubility in water and polar organic solvents such as ethanol and methanol. Because polar groups can form hydrogen bonds or other intermolecular forces with water or polar solvent molecules to promote dissolution. In non-polar organic solvents such as n-hexane and benzene, the solubility may be lower, because the force between non-polar solvent molecules is weak. The density of
    is related to the molecular weight and the degree of molecular accumulation. This molecule contains a variety of atoms and has a relatively large mass. If the molecules are tightly packed, the density may be larger, or heavier than water under the same conditions.
    The refractive index reflects the ability of a substance to refract light and is related to the molecular structure and electron cloud distribution. Due to the variety of atoms and chemical bond types in the molecule, the electron cloud distribution is complex, and the refractive index may have unique values, which can be used for substance identification and purity detection.
    What are the chemical properties of 1-chloro-3-nitro-5- (trifluoromethyl) benzene?
    1 + -3-amino-5- (triacetyl) benzene, which is a chemical compound. Its chemical properties are characteristic, and it is easy to react like a chemical, such as substitution. The amino group also has anti-chemical activity, which can affect the biochemical action of polymers, like acid reaction can be generated. The presence of triethyl groups affects the distribution of molecules, which affects the physical properties of the molecule.
    As far as chemical reaction is concerned, in the case of suitable components, the amino group can be bioacylated and reacted by acid anhydrides, etc., to form new amides. The atom can be replaced by other groups under some catalytic components, and various derivatives can be derived.
    Due to its specific chemical properties, this compound may have a variety of uses in the fields of chemical synthesis, materials science, etc. In chemical synthesis, it may be used in the field of chemical synthesis, and by virtue of its anti-chemical activity, it can build a biologically active molecule. In the field of materials, or because of its molecular properties, it can affect the properties of materials, such as light, etc., and is used for the research of new materials.
    Therefore, the chemical properties of 1 + - 3 -amino-5- (triethyl) benzene are not rich, and there may be prospects for further research and exploration in the field of chemical synthesis.
    What is the production method of 1-chloro-3-nitro-5- (trifluoromethyl) benzene?
    The preparation of 1 + -bromo-3-amino-5- (trifluoromethyl) pyridine is a very important issue in the field of organic synthesis. To make this substance, you can follow the following ancient techniques:
    The method of nucleophilic substitution is first introduced. Choose a suitable halogenated pyridine as the starting material, such as 1-halogen-3-nitro-5- (trifluoromethyl) pyridine, which can be chlorine, bromine, etc. React with nucleophilic reagents, such as liquid ammonia or ammonia alcohol solutions. The nitrogen atom of ammonia nucleophilically attacks the carbon site attached to the halogen atom of halopyridine, and the halogen atom leaves to form 3-amino-1-halo-5- (trifluoromethyl) pyridine. In this step, attention should be paid to the reaction temperature, ammonia concentration and reaction time. If the temperature is too low, the reaction will be slow, and if it is too high, it will cause side reactions.
    Next, the step of reducing and dehalogenation will be carried out. Choose suitable reducing agents, such as lithium aluminum hydride and sodium borohydride with transition metal catalysts, such as palladium carbon. Lithium aluminum hydride has strong reductive properties. In anhydrous organic solvents, it can effectively reduce and remove the halogen atom of 3-amino-1-halo-5- (trifluoromethyl) pyridine to obtain the target product 1 + -bromo-3-amino-5- (trifluoromethyl) pyridine. During operation, lithium aluminum hydride needs to be taken with care because it reacts violently with water.
    In addition, metal catalytic coupling can also be used. The pyridine derivatives containing suitable substituents are selected, and the reagents containing bromine and amino precursors are coupled under the catalysis of metal catalysts such as palladium and nickel complexes. Taking palladium catalysis as an example, the ligand has a great influence on the selectivity and activity of the reaction. The reaction system needs to be oxygen-free and anhydrous, and is often protected by inert gas. By regulating the amount of catalyst, reaction temperature and time, the reaction proceeds in the direction of generating the target product.
    In addition, there is still a way to construct the pyridine ring first. Using raw materials containing trifluoromethyl and other related substituents, the pyridine ring is constructed through multi-step reaction, and then bromine and amino groups are introduced. Although this process is complicated, the reaction sequence and conditions can be flexibly adjusted to achieve higher yield and purity.
    In short, there are many methods for synthesizing 1 + -bromo-3-amino-5- (trifluoromethyl) pyridine, and the optimal method should be selected according to actual needs, considering factors such as raw material availability, cost, and difficulty of reaction conditions.
    Precautions for storage and transportation of 1-chloro-3-nitro-5- (trifluoromethyl) benzene
    1 + -Alkane-3-amino-5- (triethylamino) benzene requires attention to many matters during storage and transportation. This is a rather special class of chemical substances with unique properties and should be handled with extreme caution.
    The first thing to pay attention to is its stability. Under certain conditions, this substance may undergo chemical reactions and cause it to deteriorate. Therefore, when storing, it is necessary to choose a dry, cool and well-ventilated place, away from fire, heat and oxidants, etc., to prevent dangerous reactions.
    Furthermore, its toxicity cannot be ignored. When coming into contact with this substance, it is necessary to take protective measures, such as wearing suitable protective gloves, masks and goggles, to avoid direct contact with the skin, eyes and respiratory tract to prevent damage to the human body.
    When transporting, there are also many points. Appropriate transportation methods and packaging materials should be selected in accordance with relevant regulations. Packaging must be tight and reliable to prevent leakage. At the same time, suitable temperature and humidity conditions should be maintained during transportation to prevent changes in the properties of the substance due to environmental factors.
    In addition, for the storage and transportation of this substance, relevant operators should have professional knowledge and skills, familiar with its characteristics and emergency treatment methods. In the unfortunate event of an unexpected situation such as leakage, it needs to be dealt with immediately according to the established emergency plan to reduce the harm. In short, the storage and transportation of 1 + -alkane-3-amino-5- (triethylamino) benzene is a safety issue and must not be taken lightly.