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1-Chloro-3-Fluoro-5-Methylbenzene

1-Chloro-3-Fluoro-5-Methylbenzene

Hongda Chemical

Specifications

HS Code

680291

Chemical Formula C7H6ClF
Molar Mass 146.57 g/mol
Appearance Liquid (usually)
Boiling Point Approx. 148 - 150 °C
Solubility In Water Insoluble (aromatic halides generally have low water solubility)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether, etc.
Odor Aromatic, characteristic odor of aromatic halides

As an accredited 1-Chloro-3-Fluoro-5-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - chloro - 3 - fluoro - 5 - methylbenzene in 500 - mL glass bottles, 10 bottles per carton.
Storage 1 - Chloro - 3 - fluoro - 5 - methylbenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly closed container made of compatible materials, such as steel or certain plastics. Store it separately from oxidizing agents and reactive substances to prevent potential chemical reactions.
Shipping 1 - Chloro - 3 - fluoro - 5 - methylbenzene is shipped in sealed, corrosion - resistant containers. It's transported under regulated conditions, following hazardous chemical shipping protocols to ensure safety during transit.
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1-Chloro-3-Fluoro-5-Methylbenzene 1-Chloro-3-Fluoro-5-Methylbenzene
General Information
Historical Development
1 - Chloro - 3 - Fluoro - 5 - Methylbenzene is an organic compound, and its historical development is worth exploring. In the past, chemical research was at the beginning, and many scholars focused on the analysis and synthesis of organic molecules. At that time, those who explored this compound used exquisite experimental techniques to solve its molecular mysteries.
At first, scholars worked hard in the laboratory and tried repeatedly to synthesize this compound. With the passage of time, the technology became more and more mature, and the synthesis efficiency gradually increased. In the early days, it was limited by instruments and theories, and progress was slow. However, chemists were persistent and made unremitting improvements.
In modern times, science and technology took off and analytical instruments became more accurate, providing strong support for in-depth understanding of the properties and reaction mechanism of 1 - Chloro - 3 - Fluoro - 5 - Methylbenzene. Its application field has also gradually expanded, emerging in the pharmaceutical, materials and other industries, and contributing to human well-being.
Product Overview
1 - Chloro - 3 - Fluoro - 5 - Methylbenzene is an organic compound. It has a unique chemical structure, with chlorine atoms, fluorine atoms and methyl atoms on the benzene ring. Looking at its physical properties, under room temperature, or as a colorless liquid, it has a certain volatility and a specific odor.
On the method of preparation, it can be achieved through a variety of organic reactions. For example, using a suitable benzene derivative as the starting material, introducing chlorine and fluorine atoms by halogenation reaction, and then adding methyl groups by methylation reaction. After several steps of reaction, carefully adjusting the reaction conditions, such as temperature, type and dosage of catalyst, etc., this compound can be obtained.
In the chemical industry, this compound has a wide range of uses. It can be used as an intermediate in organic synthesis to prepare various materials and drugs with special properties. Its chemical properties are active and can participate in many chemical reactions, providing an important foundation for the research and application of organic synthetic chemistry.
Physical & Chemical Properties
1 - Chloro - 3 - Fluoro - 5 - Methylbenzene is an organic compound, and its physicochemical properties are crucial. This substance is mostly liquid at room temperature and has a special odor. Its boiling point is related to the gasification temperature of the substance, which is of great significance for separation and purification. The melting point determines its solid-liquid transition conditions.
In terms of solubility, the compound has good solubility in organic solvents, such as common ethanol, ether, etc. This property is conducive to its use as a reactant or solvent in organic synthesis reactions. Its chemical properties are active, chlorine and fluorine atoms on the benzene ring can undergo substitution reactions, and methyl can also participate in many reactions. It can be used to prepare a variety of organic materials and pharmaceutical intermediates, and has broad application prospects in the chemical and pharmaceutical fields. It is a compound worthy of further investigation.
Technical Specifications & Labeling
1 - Chloro - 3 - Fluoro - 5 - Methylbenzene is an important chemical substance. Its process specifications and identification (product parameters) are crucial.
In terms of process specifications, the preparation of this substance requires the selection of high-purity raw materials and the fusion according to the exact ratio. During the reaction process, the temperature and pressure must be precisely controlled. For example, the reaction temperature should be maintained in a specific range to ensure that the reaction is efficient and there are few side reactions.
When it comes to labeling, its chemical name, molecular formula, molecular weight and other basic information should be clearly marked. At the same time, its hazards, such as toxicity and flammability, should also be clearly marked. In this way, users can understand its characteristics, ensure safe operation, and accurately apply it to the required fields, ensuring the smooth progress of production and research.
Preparation Method
1 - Chloro - 3 - Fluoro - 5 - Methylbenzene is an organic compound. The preparation method, raw materials and production process, reaction steps, and catalytic mechanism are all key.
To prepare this substance, 3 - Fluoro - 5 - Methylbenzenamine can be selected as the starting material. First, it reacts with sodium nitrite and hydrochloric acid at low temperature to form diazonium salts. This step requires precise temperature control to prevent the decomposition of diazonium salts.
Then, the diazonium salt is reacted with the hydrochloric acid solution of cuprous chloride, and the diazonium group is replaced by the chlorine atom to obtain 1-Chloro-3-Fluoro-5-Methylbenzene. In this reaction, the cuprous chloride is the catalyst to accelerate the reaction process.
The reaction steps must be carefully operated in sequence, and the purity of the raw materials also affects the quality of the product. In the catalytic mechanism, cuprous chloride forms an intermediate with the diazonium salt, which reduces the activation energy of the reaction and promotes the smooth progress of the reaction. This can efficiently prepare 1-Chloro-3-Fluoro-5-Methylbenzene.
Chemical Reactions & Modifications
Guanfu 1 - Chloro - 3 - Fluoro - 5 - Methylbenzene, in the field of chemistry, its reaction and modification are quite important to our generation.
In the past, when exploring the way of its reaction, it often encountered difficulties. The conventional method may not achieve the expected results, and its unique structure makes it difficult to follow the usual path. However, we did not give up and devoted ourselves to the study.
After various attempts, we found that in a specific environment, with a certain reagent, the reaction can be improved. When modifying, it was also found that subtle changes could cause differences in its properties.
In this way, the reaction and modification of 1 - Chloro - 3 - Fluoro - 5 - Methylbenzene have gradually gained. This is the road of chemical exploration. Although it is difficult and there are no surprises, it will make more progress in the future, adding to the chemical industry.
Synonyms & Product Names
1 - Chloro - 3 - Fluoro - 5 - Methylbenzene, which has attracted much attention in my chemical research. Its synonymous name is also commonly discussed in the academic world.
In the past study, Zhu Xian Da called it by different names. Or because of different research focuses, or because of different regional customs, various synonymous names were born. And the names of trade names also have their own characteristics, all of which identify this chemical thing.
Today's investigation by our generation aims to sort out its synonymous names and trade names. In the past records, it may be called "chlorofluoromethylbenzene variants", which is summarized from its chemical structure characteristics. In the trade name, there is also the trade name "Teflon chlorotoluene", in order to highlight its characteristics and attract attention.
Although there are many names, they all refer to this 1-Chloro-3-Fluoro-5-Methylbenzene. Examining its synonymous name and trade name in detail is meaningful in chemical research and industrial applications, which can help us better understand its properties and make good use of its properties.
Safety & Operational Standards
1-Chloro-3-fluoro-5-methylbenzene safety and operating practices
For 1-chloro-3-fluoro-5-methylbenzene, chemical products are also related to safety and operating practices and are of paramount importance.
For storage, it should be placed in a cool, dry and well-ventilated place. Keep away from fires, heat sources, and avoid mixing with oxidants, acids, etc. If placed in a humid place, or improperly mixed with other substances, it may cause chemical reactions and cause danger.
When operating, make sure that the operator is professionally trained and familiar with the operating procedures. Wear suitable protective clothing, protective gloves, goggles, etc. Because the product may be irritating, it may touch or hurt the skin, eyes and eyes. Good ventilation equipment is required in the operation room to disperse volatile gas and avoid accidents such as poisoning caused by excessive concentration in the air.
When handling, it should be lightly loaded and unloaded to prevent damage to packaging and containers. If the packaging is damaged, the product leaks and should be disposed of immediately. Small leaks can be absorbed by inert materials such as sand and vermiculite and collected in airtight containers; if there are large leaks, they need to be built into embankments or dug for containment, transferred to tankers or special collectors with explosion-proof pumps, recycled or transported to waste disposal sites.
Furthermore, in the place where the product is used, there should be corresponding varieties and quantities of fire fighting equipment and leakage emergency treatment equipment. In case of fire danger, it can be rescued with dry powder, carbon dioxide and other fire extinguishing agents according to its characteristics.
In short, in the entire life cycle of 1-chloro-3-fluoro-5-methylbenzene, from storage, operation to handling, safety and operating standards should be strictly observed to prevent accidents, ensure personnel safety and environmental harmlessness.
Application Area
1 - Chloro - 3 - Fluoro - 5 - Methylbenzene is an important chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often a key intermediate, helping to create many special drugs, with its unique chemical structure, giving drugs specific activity and curative effect. In the field of materials science, it can be used to prepare new materials with excellent properties, such as materials with special optical and electrical properties, to meet the needs of high-tech industries. In the field of fine chemicals, it also plays a key role, and can derive a variety of high-value-added fine chemicals for the production of coatings, fragrances, etc. Therefore, 1 - Chloro - 3 - Fluoro - 5 - Methylbenzene is of great value in many application fields and is of great significance to promote the development of related industries.
Research & Development
Today there is a thing named 1 - Chloro - 3 - Fluoro - 5 - Methylbenzene. We study it chemically, observe its properties, and investigate its changes.
In the process of research, examine its structure in detail, and explore its intermolecular force. After various experiments, we know the rules of its reaction. Or combine with other things, or decompose, there are traces to follow.
We hope to use this thing as a basis, seek technological progress, and promote the prosperity of the industry. Hope to be able to develop its growth in the fields of medicine and materials, and use it widely. After long-term research and accumulation of gains, we hope this thing will shine in the future, help the prosperity of science and technology, and lead the way of development.
Toxicity Research
The toxicity of 1 - Chloro - 3 - Fluoro - 5 - Methylbenzene is quite important. This compound has a unique structure and contains chlorine, fluorine and methyl based on the benzene ring.
After various experiments, it may be potentially harmful to organisms. In animal experiments, a small amount of exposure may cause slight discomfort, such as slightly different behavior and slightly reduced eating. If exposed for a long time and in large quantities, it may damage the function of organs, especially the liver and kidneys.
Investigate the mechanism of its toxicity, or the molecular structure interacts with key molecules in organisms to disrupt normal biochemical reactions. The properties of chlorine and fluorine atoms may change the reaction activity and affect cell metabolism.
Furthermore, the diffusion of this substance in the environment also needs to be paid attention to. It persists in soil, water, or for a long time, affecting the ecological balance. Therefore, the toxicity study of 1-Chloro-3-Fluoro-5-Methylbenzene should not be slack, so as to ensure the well-being of all beings and the tranquility of the environment.
Future Prospects
I have tried to study the technology of chemical industry, and I have worked hard on 1 - Chloro - 3 - Fluoro - 5 - Methylbenzene. It is unique in nature and has a wide range of uses. It can be used in the fields of medicine and materials.
Although the technology is gradually improving today, there are still ambitions for the future. I hope to optimize the method of its preparation, so that the process is simple and the cost is reduced, and the yield is greatly improved. And if you want to explore its new applications, you may be able to emerge in the field of new energy, contributing to the progress of the world.
I also think of the chemical industry, which is related to the ecology. In the future, we must pay attention to environmental protection, so that the production and use of this product are in harmony with nature. Although the road ahead is long, my heart is firm, and I am committed to the future development and the prosperity of the chemical industry. I will make unremitting efforts, hoping to achieve what I hope and live up to what I have learned.
Where to Buy 1-Chloro-3-Fluoro-5-Methylbenzene in China?
As a trusted 1-Chloro-3-Fluoro-5-Methylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Chloro-3-Fluoro-5-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-chloro-3-fluoro-5-methylbenzene?
1 + -3 + -methylnaphthalene, which is an organic compound. Its main uses are quite extensive.
In the chemical industry, it can be used as a raw material for the synthesis of many important organic materials. For example, after specific chemical reactions, it can be used to prepare high-molecular polymers with excellent properties. These polymers are widely used in plastics, fibers and other industries, such as the manufacture of engineering plastics with high strength and wear resistance, or high-performance fiber materials for the textile industry, providing a solid material foundation for industrial production.
In the dye industry, 1 + -3 + -Jiang-5 + -methylnaphthalene also plays an important role. Using it as a starting material, dyes with bright colors and good stability can be synthesized. Such dyes can not only be used for fabric dyeing, giving fabrics rich and diverse colors, but also indispensable in printing inks and other fields, helping to achieve exquisite pattern printing.
In addition, in the field of medicinal chemistry, it can be used as a key intermediate in the synthesis of certain bioactive compounds. These bioactive compounds, after further research and development, may become drugs for treating specific diseases and contribute to human health.
To sum up, 1 + - 3 + - methylnaphthalene, with its unique chemical structure, plays a key role in many fields such as chemical engineering, dyes, and medicine, and is of great significance to the development of various industries.
What are the physical properties of 1-chloro-3-fluoro-5-methylbenzene?
The physical properties of 1 + -deuterium-3 + -tritium-5 + -methylnaphthalene are as follows:
Deuterium is an isotope of hydrogen. Its mass number is two, and compared with ordinary hydrogen atoms, there are more neutrons in the nucleus. The elemental substance of deuterium is heavy hydrogen. It is a colorless and odorless gas at room temperature and pressure, and its properties are slightly different from those of hydrogen. Its melting boiling point is slightly higher than that of hydrogen, the melting point is about -254.4 ° C, and the boiling point is about -249.5 ° C. Due to the presence of a neutron, it has a large mass. In chemical reactions, the rate is slightly different from that of hydrogen. This difference anomaly is used in the study of chemical kinetics.
3 + -tritium is also an isotope of hydrogen, with a mass number of three, and the nucleus contains two neutrons. Tritium is radioactive and will decay into helium-3 through beta decay, with a half-life of about 12.43 years. At room temperature and pressure, tritium gas is also a colorless and odorless gas. Its physical properties are also different from hydrogen and deuterium. Its melting and boiling point is higher than that of deuterium, with a melting point of about -252 ° C and a boiling point of about -248 ° C. Due to its radioactivity, it is widely used in the field of nuclear energy and the preparation of some specially labeled compounds.
5 + -methylnaphthalene is an organic compound. At room temperature, it is a colorless to yellow oily liquid with a special smell of naphthalene. Its density is about 1.025g/cm ³, its melting point is about -30.5 ° C, and its boiling point is about 245.9 ° C. It is insoluble in water and soluble in organic solvents such as ethanol and ether. Because its molecular structure contains naphthalene ring and methyl group, it has the general properties of aromatic hydrocarbons and can undergo substitution, addition and other reactions. It is often used as a raw material in the synthesis of other organic compounds in the chemical industry.
Is 1-chloro-3-fluoro-5-methylbenzene chemically stable?
To "1+-+%E6%B0%AF+-+3+-+%E6%B0%9F+-+5+-+%E7%94%B2%E5%9F%BA%E8%8B%AF" this substance, in order to determine whether its chemical properties are stable, it is necessary to study its structure and bonding.
The stability of molecules is related to the strength of chemical bonds. Carbon-carbon bonds are important in organic compounds. In this substance, carbon chains are connected in a specific order, and groups such as methyl groups also affect their properties.
If its carbon-carbon bond is a saturated single bond, the electron cloud of the single bond overlaps to a high degree, and the bond energy is relatively large. If it wants to break, it requires more energy, so its chemical properties tend to be stable, and it is not easy to react violently with other substances. For example, alkanes are mostly connected by single bonds, and they are inert to many reagents at room temperature and pressure.
However, if it contains unsaturated double or triple bonds, the electron cloud distribution is different from that of single bonds. The electron cloud density is higher, and it is more susceptible to the attack of electrophilic reagents or free radicals, causing it to undergo reactions such as addition and oxidation, and its chemical properties are not very stable.
The effect of the group cannot be ignored. Methyl is an electron supply group, which can increase the density of the linked carbon electron cloud, or affect the polarity and reactivity of the molecule.
To sum up, only the name of "1+-+%E6%B0%AF+-+3+-+%E6%B0%9F+-+5+-+%E7%94%B2%E5%9F%BA%E8%8B%AF" is known, and its exact structure is not detailed, so it is difficult to determine whether its chemical properties are stable or not. It is necessary to know its structural characteristics in detail before its stability under different conditions can be determined according to chemical principles.
What is the production process of 1-chloro-3-fluoro-5-methylbenzene?
The production process of Fu 1 + -deuterium-3 + -tritium-5 + -methylnaphthalene is an important matter in the chemical industry. The method is as follows:
First, the raw materials are selected, and high-purity related materials must be selected. Deuterium and tritium need to be finely purified to ensure that there are few impurities, and methylnaphthalene also needs to reach high quality before laying the foundation for subsequent steps.
In the second step of the reaction, deuterium, tritium and methylnaphthalene are inserted in a special reactor according to the precise ratio. The control of reaction temperature and pressure is the key, and it should be adjusted to an appropriate degree according to the specific chemical reaction principle. In general, the temperature may need to be maintained at a certain range, and the pressure should also meet the needs of the reaction to promote the effective synthesis of various substances.
Furthermore, during the reaction process, the addition of catalysts can change the rate and direction of the chemical reaction. The selection of suitable catalysts can improve the generation efficiency and purity of the product. However, the amount of catalyst and the timing of addition need to be carefully considered, so as not to affect the overall reaction process.
After the reaction, the separation and purification of the product should not be underestimated. Using distillation, extraction and other methods, the target product is finely separated from the reaction mixture, and the unreacted raw materials, by-products and impurities are removed to obtain high-purity 1 + -deuterium-3 + -tritium-5 + -methylnaphthalene.
Each step requires strict compliance with the operating procedures and fine control of various parameters in order to achieve excellent production technology and obtain high-quality products.
What should I pay attention to when storing and transporting 1-chloro-3-fluoro-5-methylbenzene?


If there is no need to store methylnaphthalene, it is appropriate to pay attention to it.
If it is not stored, it is the first environment. It is a good place for dryness, safety, and good communication. Avoid direct sunlight. If it encounters light or high temperature, it is afraid of melting, and it is not harmful. And it is sensitive, and the tide environment is easy to cause reaction, and its products are damaged.
For secondary containers. A well-sealed container should be used to prevent it from escaping and prevent the intrusion of external objects. And the containing equipment is compatible with 1 + - 3 + -oxygen-5 + -methylnaphthalene, which does not biochemically react and maintains its integrity.
Furthermore, there are no sources of ignition, oxygen and oxidation where they are stored. This is because 1 + - 3 + -oxygen-5 + -methylnaphthalene is flammable, and in case of open flame, high temperature or oxidation, it is easy to ignite and explode, endangering safety.

There are also many reasons to do so. Tools are dry and dry, to avoid contamination of 1 + - 3 + -oxygen-5 + -methylnaphthalene. And on the way, it is necessary to maintain a fixed degree of temperature and temperature to prevent strong shocks and collisions, which will cause the container to break and leak.
In addition, people are familiar with the characteristics of 1 + - 3 + -oxygen-5 + -methylnaphthalene and the way of emergency disposal. In the event of an accident such as leakage, appropriate measures can be taken in time to minimize harm.
Therefore, 1 + - 3 + - oxygen-5 + - methylnaphthalene should be kept in storage, from the environment, container to operation, etc., to ensure the safety of its products.