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1-Chloro-3,4-Difluorobenzene

1-Chloro-3,4-Difluorobenzene

Hongda Chemical

Specifications

HS Code

393571

Chemical Formula C6H3ClF2
Molar Mass 148.54 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 139 - 141 °C
Density 1.326 g/cm³ (approximate)
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
Flash Point 38 °C (closed cup, approximate)
Odor Characteristic aromatic odor
Stability Stable under normal conditions

As an accredited 1-Chloro-3,4-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - chloro - 3,4 - difluorobenzene in 5 - liter sealed drums for safe storage.
Storage 1 - Chloro - 3,4 - difluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly closed container, preferably made of materials resistant to its corrosive nature. Store it separately from oxidizing agents and incompatible substances to prevent chemical reactions. Ensure the storage area is dry to avoid potential hydrolysis.
Shipping 1 - Chloro - 3,4 - difluorobenzene is shipped in tightly sealed, corrosion - resistant containers. It's transported in accordance with hazardous chemical regulations, ensuring proper handling to prevent spills and environmental risks.
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1-Chloro-3,4-Difluorobenzene 1-Chloro-3,4-Difluorobenzene
General Information
Historical Development
1 - Chloro - 3,4 - Difluorobenzene is an important chemical product. Its historical development can be traced. In the past, chemical research has not yet reached the current state, and the exploration of compounds containing chlorofluorocarbons is still shallow. However, with the passage of time, chemists have diligently studied, analyzed the properties of substances, and explored synthesis methods.
At the beginning, the synthesis of this compound was difficult, the raw materials were rare, and the reaction conditions were harsh. However, the predecessors chemists were fearless and difficult, and failed repeatedly. After long-term grinding, breakthroughs have been made in the screening of reaction raw materials, the ratio, and the control of reaction temperature and pressure. With the gradual development of technology, the instruments are more precise, and the synthesis process is also becoming more and more perfect. From simple workshop operation, to large-scale and standardized production. This compound has emerged in many fields, contributing to the development of the chemical industry, and is actually the result of unremitting progress in chemical research.
Product Overview
1 - Chloro - 3,4 - Difluorobenzene is an important chemical substance. It is a colorless to slightly yellow liquid with a special odor. This substance has a wide range of uses in the field of organic synthesis, and is often used as an intermediate to prepare various drugs, pesticides and functional materials.
Looking at its chemical structure, above the benzene ring, the chlorine atom is cleverly connected to two fluorine atoms. This structure gives it unique chemical properties, stability and reactivity. Because it contains halogen atoms, it can participate in many nucleophilic substitution reactions, which can effectively construct new carbon-halogen bonds or carbon-carbon bonds.
To synthesize this substance, a specific halogenation reaction path is adopted, and the reaction conditions, such as temperature and catalyst, are precisely controlled to obtain higher yield and purity. And its value in the chemical industry is becoming increasingly apparent, making great contributions to promoting technological innovation and product upgrading in related fields, with promising prospects.
Physical & Chemical Properties
1 - Chloro - 3,4 - Difluorobenzene is an organic compound, and its physicochemical properties are very important. This substance is mostly liquid at room temperature and has a special odor. Looking at its physical properties, the boiling point is suitable, which is conducive to separation and purification operations. Its density is slightly higher than that of water, and it has unique performance in specific reaction systems.
Regarding chemical properties, chlorine and fluorine atoms in this compound are active. Chlorine atoms can undergo substitution reactions. When encountering nucleophiles, they can be replaced by other groups, opening a new compound synthesis path. Fluorine atoms enhance molecular stability and electronegativity, affecting reactivity and selectivity. These properties have laid the foundation for many reactions in the field of organic synthesis, allowing chemists to build complex and functionally specific organic molecules, driving the development of organic chemistry, with great potential for applications in drug discovery, materials science, and many other fields.
Technical Specifications & Labeling
1 - Chloro - 3,4 - Difluorobenzene is a chemical I have been studying recently. Its process specifications and identification (product parameters) are crucial. In terms of process specifications, the selection of raw materials needs to be precise, and the purification steps must be carefully controlled to ensure the purity of the product.
In terms of identification, product parameters need to be clearly marked. From the appearance point of view, it should be colorless and transparent. When the purity reaches a very high standard, the impurity content must be strictly controlled. These two are related to product quality and application field. Only by strictly abiding by process specifications and accurately marking product parameters can 1 - Chloro - 3,4 - Difluorobenzene play its due effectiveness in various fields of chemical industry, and it is of key significance in scientific research and production.
Preparation Method
1 - Chloro - 3,4 - Difluorobenzene is an important chemical raw material. The preparation method, raw materials and production process are the key. Commonly used raw materials include specific aromatic hydrocarbons and chlorine and fluorine-containing reagents.
In the production process, the reaction steps are rigorous. First, aromatic hydrocarbons and chlorine-containing reagents are substituted under suitable catalyst and reaction conditions to introduce chlorine atoms. Afterwards, they are reacted with fluorine-containing reagents to introduce fluorine atoms. Among them, the reaction temperature, pressure, and the type and dosage of catalysts all have a significant impact on the reaction effect.
To optimize the preparation, the activation mechanism needs to be paid attention to. The activity and selectivity of 1-Chloro-3,4-Difluorobenzene can be improved by adjusting the activity check point of the catalyst. In this way, through fine regulation of each link, 1-Chloro-3,4-Difluorobenzene can be efficiently prepared to meet the needs of industrial production.
Chemical Reactions & Modifications
1 - Chloro - 3,4 - Difluorobenzene is an important raw material for organic synthesis. The study of its chemical reaction and modification is of great significance in the field of chemistry.
In the past, this compound was prepared under harsh reaction conditions and the yield was not high. Today's chemists are working hard to find ways to optimize. After repeated experiments, the reaction path was improved, such as selecting a suitable catalyst, adjusting the reaction temperature and time.
Taking a new catalyst as an example, under mild conditions, the reaction rate and yield can be greatly improved. This not only saves energy, but also reduces production costs. And after modification, the chemical properties of 1 - Chloro - 3,4 - Difluorobenzene are more stable, and the application range can be expanded. In the fields of medicine, pesticides, etc., it has better performance, contributing to the development of the chemical industry.
Synonyms & Product Names
1 - Chloro - 3,4 - Difluorobenzene, which is also known as 3,4 - difluorobenzene. Although the names are different, they all refer to the same. In the field of chemical industry, the names are different, often due to convention or industry habits.
Ancient scholars, in the name of the thing, are also true. Although the times are different, it is a good idea to seek the name. Today 1 - Chloro - 3,4 - Difluorobenzene, in commerce, is a chemical raw material, which can be used in various synthetic industries.
In various cities, or known as 3,4 - difluorobenzene, or call it by its English name. Although the two are different in shape, they all refer to this specific compound. It has a wide range of uses and is an indispensable raw material in the pharmaceutical, pesticide and other industries. Therefore, although the name is different, it is actually the same thing, which has made a great contribution to the progress of chemical industry.
Safety & Operational Standards
1 - Chloro - 3,4 - Difluorobenzene is an important substance in chemical research. It is crucial to its safety and operation standards and should not be ignored.
At the beginning of preparation, all raw materials used must be carefully inspected to ensure that they are pure and free of impurities, so as not to introduce impurities and affect the quality of the product. The storage of raw materials must also be placed in a suitable environment according to their characteristics to prevent deterioration.
When operating, all instruments must be carefully checked in advance to ensure that they are intact and functional. The experimental site should be well ventilated to disperse harmful gases that may be generated. Operators must wear strict protective equipment, such as protective clothing, protective gloves, protective goggles, etc., to prevent accidental contact with the substance and endanger their own safety.
During the reaction process, temperature, pressure and other conditions must be precisely controlled without slight deviation. Due to the reaction of 1-Chloro-3,4-Difluorobenzene, the conditions are quite sensitive, subtle changes, or the reaction results are very different, and even accidents occur. And factors such as stirring rate cannot be ignored, and must be adjusted reasonably according to the reaction requirements.
After the product is made, its storage also has strict requirements. It should be placed in a cool, dry and ventilated place, away from fire sources and oxidants, to prevent danger such as fire or explosion. At the same time, it must be clearly marked to indicate its characteristics and hazards for others to identify.
Waste disposal should also be done with caution. It should not be discarded at will. It must be collected in accordance with relevant regulations and disposed of properly to prevent environmental pollution.
In short, the safety and operation standards of 1-Chloro-3,4-Difluorobenzene are interlinked, and no link should be lost. Chemical researchers should be rigorous and strictly abide by the regulations to ensure the safety of the experiment and achieve the research goals smoothly.
Application Area
1 - Chloro - 3,4 - Difluorobenzene is an important chemical substance. It has a wide range of application fields and is often a key intermediate in the field of pharmaceutical synthesis. Due to the unique chemical structure of this substance, it can introduce specific functional groups for many drug molecules and help create drugs with novel curative effects.
In the field of materials science, it also shows unique value. It can participate in the synthesis of special polymer materials. Through chemical modification, it can improve the thermal stability, mechanical properties and other key characteristics of materials, and meet the needs of high-end fields such as electronics and aviation for special materials.
Furthermore, in the fine chemical industry, it is used as a starting material for the synthesis of special fragrances and dyes, endowing products with unique properties and colors, expanding the diversity of fine chemical products, and promoting technological innovation and product upgrading in related industries.
Research & Development
In recent years, I have focused on the research of 1 - Chloro - 3,4 - Difluorobenzene. This compound has unique physicochemical properties and potential application opportunities in many fields.
At the beginning of the study, analyze its synthesis method. The traditional path has complicated drawbacks and is time-consuming and expensive. I have tried my best to find ways to improve. After repeated experiments, a new catalyst was used to optimize the reaction conditions, resulting in a significant increase in yield and high purity.
As for its application and expansion, in the field of medicine, it can be used as a key intermediate to help create new drugs. In materials science, it may contribute to the research and development of high-performance materials.
However, the research road is not smooth, facing the challenges of cost control and environmental compliance. In the future, I will continue to study, hoping to find a solution to promote 1 - Chloro - 3,4 - Difluorobenzene from experiment to wide application, and contribute to scientific research and industrial development.
Toxicity Research
Toxicity of 1 - Chloro - 3,4 - Difluorobenzene. This substance is a chemical product, which is related to toxicity research and should be done with caution. Observe its molecular structure, the existence of chlorine and fluorine atoms, or affect its chemical and biological activities.
After various experiments, observe its effects on organisms. Take white mice as a test, feed them food containing this substance, and after a few days, the behavior and physiology of white mice have changes. Its movement and stop are sluggish, the amount of food eaten is reduced, and there are signs of damage to the organs.
When this substance is applied to the soil, the growth of plants is hindered, the buds and leaves are yellowed, and the development is delayed. From this point of view, 1-Chloro-3,4-Difluorobenzene has certain toxicity and has adverse effects on the growth and physiological function of organisms. The results of research can provide a basis for the use, protection and environmental impact measurement of this substance in the future.
Future Prospects
1 - Chloro - 3,4 - Difluorobenzene is also a new chemical substance. Looking at this substance today, its quality is pure and beautiful, and its performance is unique. It has great potential for all things in the chemical industry.
I look at its future prospects, which can be used for the development of new drugs. The medical way seeks innovation, and the power of medicinal stones depends on new materials. This substance may be the key to medicine, healing various diseases and saving people's health.
And in electronic materials, it also has potential. In today's world, electrons are fast and materials are the basis. 1 - Chloro - 3,4 - Difluorobenzene or can help the performance of electronic devices to improve, speed calculation and reduce energy consumption.
Although there is a long way to go, I firmly believe that with time and dedication, I will be able to uncover more wonders, seek well-being for the world, and become a great cause in the future, with unlimited possibilities.
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Frequently Asked Questions

As a leading 1-Chloro-3,4-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-chloro-3,4-difluorobenzene?
What is the main use of 1-%-3,4-diene? This is one of the most important chemical materials. 1-%-3,4-diene is often used in many fields.
First, in the field of synthesizing polymer materials, it is important. With its synthesizable properties, this property has good oil resistance and aging resistance, which is essential in the manufacture of seals, pipes and other components of the steam industry. For example, if the sealing ring around the automobile is formed by the synthesis of 1-%-3,4-diene, it can maintain good sealing performance in high temperature and oil immersion conditions, effectively preventing oil leakage and ensuring normal operation.
Second, 1-%-3,4-diene also plays an important role in the synthesis. It can be used for the synthesis of certain special effects. For example, some new compounds for specific diseases need to be synthesized by the specialization of 1-%-3,4-diene, and the multi-step synthesis reaction can introduce specific functionalities to create biologically active molecules, which can provide assistance for the development of materials.
Third, in the field of material surface modification, 1-%-3,4-diene can be used to improve the surface properties of materials. It can increase the wear resistance and corrosion resistance of materials by grafting to the surface of materials through specific chemical reactions. For example, the surface of gold materials can better maintain the integrity of gold in damp and corrosive environments, extend the use of materials, and have a promising future in fields with high material performance requirements such as aerospace and marine engineering.
Therefore, 1-%-3,4-diene has an indispensable use in the fields of multi-engineering and scientific research, promoting the development of various technologies.
What are the physical properties of 1-chloro-3,4-difluorobenzene?
1-% deuterium-3,4-divinylbenzene is an organic compound with unique physical properties, allowing a certain person to come to you one by one.
This compound has a certain volatility, and under normal temperature and pressure, a little smell can be felt by people. Looking at its appearance, it is often a colorless to slightly yellow transparent liquid, like smart water, but it has a bit more of the unique texture of chemical products. Its density is slightly smaller than that of water. If it is placed in the same place as water, it can be seen floating on the water surface leisurely, as if it is distinct from water, forming a small world on its own.
The boiling point of 1-% deuterium-3,4-divinylbenzene is quite considerable, and a higher temperature is required to make it boil into a gaseous state. This property allows it to maintain a relatively stable liquid state during many high-temperature reactions or separation processes. In terms of melting point, it is in a relatively low temperature range, and can solidify into a solid state under a specific low-temperature environment, just like an elf sleeping in a low-temperature dream.
Furthermore, its solubility is also worth mentioning. It is soluble in a variety of organic solvents, such as common ethanol, ether, etc., like a wanderer into the arms of a foreign land, and blends with it. However, it is difficult to dissolve in water, as if there is an invisible barrier between water and it, and the two are difficult to mix intimately.
In addition, 1-% deuterium-3,4-divinylbenzene also has a certain refractive property. When light passes through it, a wonderful refraction phenomenon occurs, as if giving light a different path, allowing the viewer to appreciate the wonderful changes in the optical world. This refractive property may play a unique role in some optical materials or in the field of analytical detection.
Is 1-chloro-3,4-difluorobenzene chemically stable?
For 1-% -3,4-divinylbenzene, its chemical properties are determined. In this compound, the atomic interaction of divinylbenzene results in a phase solidification mechanism.
For its chemical properties, both carbon-carbon and carbon-carbon have certain chemical properties. Carbon-carbon is generally stable and not easy to crack; while carbon-carbon in divinylbenzene has a certain anti-activity, but in general conditions, if a specific anti-reaction is detected, it will also generate anti-reaction.
Furthermore, the molecular shape of 1-% -3,4-divinylbenzene makes it have a certain space resistance effect. The empty arrangement of the substituents and atoms in the surrounding area can prevent other compounds from being easily accessible to the active parts of the molecule to a certain extent, and increase their characterization.
However, the characterization is not good. Under special conditions such as high temperature, oxidation or catalysis, 1-% 3,4-divinylbenzene can also be reacted biochemically. For example, in the presence of high temperature and catalysis, its carbon-carbon content can be added to the reaction, and other small molecules can be reacted and changed.
, 1-% 3,4-divinylbenzene can be reacted under normal conditions, but under specific strong reaction conditions, it can still be reacted biochemically and exhibit its versatility.
What are the preparation methods of 1-chloro-3,4-difluorobenzene?
To prepare 1-alkane-3,4-dienyl naphthalene, the method is as follows:
First, the appropriate naphthalene derivative is taken as the starting material, and the desired substituent and carbon-carbon double bond structure are introduced through specific reaction steps. Naphthalene can be used as the base first, and the electrophilic substitution reaction can be used to introduce halogen atoms or other suitable functional groups at specific positions in the naphthalene ring. This step requires fine regulation of the reaction conditions, such as reaction temperature, reactant ratio and catalyst used. For example, the selection of suitable halogenation reagents, under appropriate solvent environment and catalytic system, makes the halogen atoms fall precisely at the predetermined check point of the naphthalene ring, which lays the foundation for the subsequent construction of the diene structure.
Then, with the help of metal-organic chemistry, such as the cross-coupling reaction catalyzed by palladium, select suitable organometallic reagents to interact with halogenated naphthalene derivatives. In this process, palladium catalysts play a key role, which can effectively promote the formation of carbon-carbon bonds. At the same time, it is necessary to strictly control the anhydrous and oxygen-free conditions of the reaction system to avoid side reactions. By ingeniously designing the structure of organometallic reagents, they can be successfully coupled with halogenated naphthalene derivatives under palladium catalysis, and gradually build a carbon skeleton structure containing the target carbon-carbon double bond.
Furthermore, after the construction of the carbon skeleton, the functional groups may need to be transformed and modified. For example, remove some protected functional groups and restore them to active forms that can be further reacted. Or use oxidation, reduction and other reactions to fine-tune specific functional groups to achieve the precise structure requirements of 1-alkane-3,4-dienaphthalene. This series of reactions needs to be based on the specific starting material and intermediate product structure, reasonably plan the reaction sequence and conditions, and properly separate and purify each step of the reaction to ensure the purity of the product, so as to successfully obtain 1-alkane-3,4-dienaphthalene.
What are the precautions for storing and transporting 1-chloro-3,4-difluorobenzene?
In the storage and storage of 1-%-3,4-divinylbenzene, the following things should be paid attention to:
The first heavy storage environment. This chemical substance should be stored in an open and open room. Because of its flammability, it is important to prevent the fire and the source from burning. If there is a slight carelessness, it will be easy to ignite and explode in case of open flame and high temperature. It also needs to be controlled, and it should not exceed 30 ° C. And it should be stored in equal parts of oxidation and acid. It must not be mixed to prevent the chemical reaction of the dangerous oil.
In terms of packaging, it must be well sealed. Efficient packaging can effectively avoid leakage and divinylbenzene leakage. If it is not released, it will not waste raw materials, and it is more likely to increase fire and explosion due to exposure to air, which may also endanger the health of people around the world.
On the way, the manufacturer is familiar with the regulations of hazardous chemical products. It is recommended to prepare the required amount of fire-fighting equipment and emergency management of leakage. In summer, it is recommended to travel in the morning and evening to avoid the increase in sunlight exposure and increase the risk. Highways should be driven according to the fixed route, and do not stay in residential and densely populated areas.
Unloading, the operator needs to unload, and it is forbidden to drop, touch, collide, and other rough handling to prevent the leakage of materials caused by package breakage. Once there is a leak, we will immediately take urgent measures, such as evacuating the crowd, isolating the leak, using composite materials to contain and absorb the leak, properly clean it up, and prevent secondary pollution.