Hongda Chemical
Products
Home  /  Products  / 

1-Chloro-2-Fluoro-4-Nitrobenzene

1-Chloro-2-Fluoro-4-Nitrobenzene

Hongda Chemical

Specifications

HS Code

198923

Chemical Formula C6H3ClFNO2
Appearance yellow - brown solid
Boiling Point 229 - 231 °C
Melting Point 39 - 43 °C
Density 1.495 g/cm³
Solubility In Water insoluble
Solubility In Organic Solvents soluble in common organic solvents like ethanol, acetone
Flash Point 104 °C
Vapor Pressure low vapor pressure

As an accredited 1-Chloro-2-Fluoro-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - chloro - 2 - fluoro - 4 - nitrobenzene: Packed in 1 - kg bottles for safe storage and transport.
Storage 1 - Chloro - 2 - fluoro - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container to prevent leakage. Since it's a hazardous chemical, the storage area should be clearly marked and accessible only to authorized personnel.
Shipping 1 - chloro - 2 - fluoro - 4 - nitrobenzene is shipped in tightly sealed, corrosion - resistant containers. It follows strict hazardous material regulations, with proper labeling and secure packaging to prevent leakage during transit.
Free Quote

Competitive 1-Chloro-2-Fluoro-4-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

1-Chloro-2-Fluoro-4-Nitrobenzene 1-Chloro-2-Fluoro-4-Nitrobenzene
General Information
Historical Development
1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene is also a chemical substance. Although the history of its development is difficult to study in detail, but going back to the past, the chemical sages have not stopped exploring. At the beginning, the chemical technology was not refined, and the understanding of such compounds was still shallow. Later, with the passage of time, technology has gradually advanced, and chemists have deepened their research. Or in accidental experiments, its characteristics are observed; or through repeated deductions, its structure is revealed. As a result, the understanding of 1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene has gradually increased. In the past, the synthesis method was crude and the yield was scarce. Today is different from the past, with the help of science and technology, the synthesis method has been refined, and the yield has also been improved. In the field of chemistry, this compound is used more and more widely, and its influence is deeper and deeper. It is actually a pearl in the long river of chemical development.
Product Overview
1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene is a chemical product that I have been working on recently. This product has unique properties, and its appearance is light yellow to light brown crystalline powder. It is quite stable at room temperature and pressure. Its melting point is suitable, about [X] ° C, which is convenient for operation and application under specific conditions.
This chemical has a delicate structure, and chlorine, fluorine, and nitro are cleverly connected to the benzene ring. The introduction of chlorine atoms gives it a certain nucleophilic substitution activity; the presence of fluorine atoms enhances molecular stability and unique reactivity; the addition of nitro groups makes the whole have unique electronic effects and reactivity.
It is widely used in the field of organic synthesis and can be used as a key intermediate to prepare a variety of high-value-added compounds, such as fine chemicals, pharmaceutical intermediates, etc. With its special structure, it can guide the reaction direction in chemical reactions and provide an effective path for the synthesis of complex organic molecules, which is an important cornerstone of organic synthetic chemistry.
Physical & Chemical Properties
1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene is an organic compound, and its physicochemical properties are particularly important. Looking at its physical properties, at room temperature, this substance is mostly solid, colored or light yellow, and has a special odor. Its melting point and boiling point are also fixed. The melting point is related to the phase change of the substance, which has a great impact on storage and transportation; the boiling point is of great significance when separating and purifying.
When talking about chemical properties, because its structure contains functional groups such as chlorine, fluorine, and nitro, the chemical activity is not low. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring and increases the difficulty of electrophilic substitution reactions. Chlorine and fluorine atoms can participate in nucleophilic substitution reactions and are widely used in the field of organic synthesis. Under specific conditions, this compound can react with many reagents to generate new organic products, which has great potential in drug synthesis and material preparation.
Technical Specifications & Labeling
1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene is an important chemical product. Its technical specifications and identification (product parameters) are extremely critical.
When it comes to technical specifications, this compound needs to meet specific purity standards, and the impurity content should be strictly limited. For example, other halogenated aromatic hydrocarbon impurities should not exceed a certain proportion to ensure the excellent quality of the product. Its appearance should be a specific color and morphology, or colorless to slightly yellow crystalline, and the melting point should be within the established range.
Regarding the logo, the chemical name "1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene" should be clearly marked on the product packaging, as well as warning labels to indicate its chemical properties and latent risk. At the same time, product parameters such as molecular weight and molecular formula should also be accurately marked so that users can understand its chemical properties and facilitate proper application and storage.
Preparation Method
1-Chloro-2-fluoro-4-nitrobenzene is an organic compound. The method of its preparation is related to the raw materials and production process, reaction steps, and catalytic mechanism.
To make this substance, the choice of raw materials is very important. It often starts with benzene, and is formed by halogenation and nitrification reactions. During halogenation, chlorine and fluorine reagents are introduced into the benzene ring in sequence to make the positioning accurate. Next, a nitrification reaction is carried out, and a mixed acid of nitric acid and sulfuric acid is used as an agent to make the nitro group enter a specific position.
The reaction step also needs to be fine. Halogenation reaction, temperature control and time control, make the reaction moderate and avoid side reactions. When nitrifying, pay attention to the ratio of acid and the reaction temperature to maintain the ideal position for the introduction of nitro groups.
In the catalytic mechanism, or use metal halide as a catalyst to promote the speed of the halogenation reaction; during nitrification, sulfuric acid can increase the activity of nitric acid and promote the introduction of nitro groups.
All these need to be carefully studied to obtain high-quality 1-chloro-2-fluoro-4-nitrobenzene products.
Chemical Reactions & Modifications
There is a substance named 1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene. In the field of chemistry, its reaction and modification are very important.
To study the reaction of this substance, looking at its structure, chlorine, fluorine and nitro groups each occupy a specific position and affect each other. Chlorine and fluorine are halogen elements with certain activity, and nitro groups have strong electron absorption.
In many reactions, due to the strong electron absorption of nitro groups, the electron cloud density of the benzene ring decreases, making the electrophilic substitution reaction difficult. However, under appropriate conditions, nucleophilic substitution can occur. If attacked with nucleophilic reagents, halogen atoms can be replaced to achieve modification.
If you want to enhance its reactivity, you can change the reaction conditions, such as adjusting the temperature and pressure, and selecting a suitable catalyst. Or modify its structure, introduce other groups, and change the electron cloud distribution, so as to optimize its reaction performance and achieve the expected chemical purpose.
Synonyms & Product Names
1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene, also known as p-fluoro-chloro-nitrobenzene. Looking at its name, it can be known that it is formed by the connection of chlorine, fluorine, nitro and benzene rings. In the chemical industry, there are many other names, or it is called according to its characteristics and uses.
This substance is widely used. In the synthesis of medicine, it is often an important intermediate, assisting in the synthesis of various drugs. In the field of pesticides, it is also a key raw material, helping to create high-efficiency pesticides.
Its many aliases vary according to different regions and industry habits. Although the names are different, they actually refer to this substance. Everyone in the industry should be familiar with their different titles in order to facilitate communication and research, avoid confusion, and enjoy unimpeded access to chemical research and development and production.
Safety & Operational Standards
1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene is a common compound in chemical research. During its production, use and storage, safety and operating standards are extremely critical.
This substance is dangerous, and its chlorine, fluorine, nitro and other functional groups give chemical activity. Chlorine atoms are active, or initiate substitution reactions; fluorine atoms are highly electronegative, which affects molecular polarity and reactivity; nitro groups are oxidizing, or cause fire and explosion risks. Therefore, the first thing to do with this substance is to protect personnel.
Operators wear professional protective clothing, including protective clothing, gloves, goggles, etc., to prevent skin contact and eye splashing. Respiratory protection is also indispensable. Appropriate respirators should be selected according to the scene to avoid the inhalation of volatile gases.
The experiment or production site needs to be well ventilated, and an effective ventilation system should be set up to drain volatile gases in time, reduce the concentration in the air, and reduce the risk of explosion and poisoning.
When storing, it should be stored in a cool, dry and ventilated place, away from fire and heat sources. Store separately from oxidants, reducing agents, alkalis, etc., and avoid mixed storage. Handling should be light and unloaded to prevent leakage caused by damaged packaging.
If a leak unfortunately occurs, personnel in the leakage contaminated area should be quickly evacuated to a safe area, quarantined, and strictly restricted access. Emergency responders wear self-contained positive pressure respirators and anti-toxic clothing. Do not let leaks come into contact with combustible substances, small leaks, mixed with sand, dry lime or soda ash, collected in dry, clean, covered containers. Large leaks, build embankments or dig holes to contain, covered with foam, reduce vapor hazards. Transfer to a tanker or special collector by pump, recycle or transport to a waste treatment site for disposal.
Operation 1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene, be sure to strictly observe safety and operating standards, so as to ensure the safety of personnel and the environment from pollution, so that research and production can be carried out in an orderly manner.
Application Area
1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene is also a chemical. Its use is not limited, and it has its own uses in many fields. In the field of research and development, it can be used as a raw material for special effects to help heal diseases and save people. In this field, it can be used as a basis for synthesis, to produce a good product for eliminating harmful seedlings and to protect the harvest of crops. And in the field of material science, it also has its use, or it can be used as a material to make it more widely needed. This compound, with its unique properties, is used in many aspects such as engineering, scientific research, etc., and is used in the world. It is an important existence in the field of chemistry, benefiting people and promoting the development of products.
Research & Development
The rise of modern chemistry is based on the study of matter and the pursuit of daily refinement. 1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene This thing, I have been studying it for years. At the beginning, I explored its structure and analyzed its properties, and after various attempts, I got the essentials. Its structure is exquisite and its properties are also unique, and it may be of great use in the field of chemical industry.
Then I found a way to prepare it, thought hard, and tried to change it again and again. After many adjustments to the distribution of raw materials and the temperature of the reaction, a good method can be obtained. The yield is gradually increasing, and the quality is also excellent.
Looking forward to its development, if its method can be widely disseminated, it may create a new situation and bring new opportunities in the pharmaceutical and material industries. I should make unremitting efforts to contribute to the advancement of chemistry and the prosperity of the industry, and live up to my research and pursuit.
Toxicity Research
1-Chloro-2-fluoro-4-nitrobenzene is one of the chemical substances. In toxicity studies, we need to be careful. In its structure, chlorine, fluorine, and nitro groups may be toxic to organisms.
Looking at the experiments of various poisons in the past, those containing halogen atoms and nitro groups are often toxic. In this compound, the presence of chlorine and fluorine atoms may change the physical and chemical properties of the compound, increase its fat solubility, and make it easy to enter the biological body. The presence of nitro groups may initiate a reduction reaction in the biological body, generating active intermediates, which damage the structure and function of cells.
Our generation should use scientific methods to study its toxicity mechanism. It can be used to observe its effects on cell proliferation and apoptosis through cell experiments; it can also be used to explore its metabolism, distribution and organ damage in vivo through animal experiments. In this way, we can know the toxicity of 1-chloro-2-fluoro-4-nitrobenzene in detail, providing a solid basis for protection and treatment.
Future Prospects
Prospects of the future, in 1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene, this product is very important. Today, this product is unique in its properties, and it may have wonderful uses in the field of chemistry.
In the future, we can hope that it will be used in the research and development of the future to make a big impact. It may be used as a first-class compound to help new technologies and solve the suffering of diseases. And in the field of materials, it may also have extraordinary performance, or it can improve the properties of materials and develop new applications.
In addition, the change of synthesis methods has not yet been an important direction. Only by making it more efficient, guaranteed, and cost-effective can it be used widely. In this way, 1 - Chloro - 2 - Fluoro - 4 - Nitrobenzene will surely be able to make a colorful chapter in the unfinished journey, and the well-being of people will be outstanding.
Where to Buy 1-Chloro-2-Fluoro-4-Nitrobenzene in China?
As a trusted 1-Chloro-2-Fluoro-4-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Chloro-2-Fluoro-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-chloro-2-fluoro-4-nitrobenzene?
1 + - - 2 + - - 4 + - Bismuth carbonyl is used in the fields of alchemy, medicine, and chemical industry.
On the way to alchemy, ancient alchemists thought that such spiritual creatures might contain the secrets of creation. Those who desire long-term growth and exuberance use it as a medicinal guide, hoping to reconcile yin and yang, clear qi and blood, and help alchemy reach a wonderful state. Looking at the Alchemy Sutra in the past, he often remembered strange things, thinking that he could enlighten the path of transcendence. Although 1 + - - 2 + - - 4 + - carbonyl bismuth is not well known to everyone, it may have a unique position in the inheritance of secret alchemy. With its unique physical properties, it helps cultivators explore the mystery of life and the mystery of heaven and earth.
In the field of medicine, there are also traces to follow. Ancient healers tried to use all kinds of gold stones and herbs as medicine. 1 + - - - 2 + - - 4 + - carbonyl bismuth, if properly processed, may have the ability to heal diseases. It may enter the meridians, reduce stagnation, and clear paralysis. In case of poor qi and blood, and congestion of meridians and collaterals, it can be used as adjuvant, or it can adjust qi and blood, so that the body can return to peace. However, its nature is strong, and it needs to be used with caution. You must follow the method of syndrome differentiation and treatment, and measure the style to avoid its harm and promote its benefits.
As for the road of chemical industry, although ancient books are fresh and detailed, it can be deduced from today's principles. Its unique chemical properties may be used for the synthesis and transformation of substances. In ancient metallurgy, dyeing and other processes, if you can make good use of its properties, you can innovate techniques and improve the quality of utensils. For example, when metallurgy, adding an appropriate amount may improve the toughness and luster of metals; when dyeing, it may help pigments adhere and last. Although the chemical industry of ancient times was not as developed as it is today, such wonders already contain unique potential, which will be explored and used by later generations of wise men.
What are the physical properties of 1-chloro-2-fluoro-4-nitrobenzene
Gas, water, and tetraaminosilane all have their own unique physical properties.
Gas is often invisible, lightweight and can fill the four directions. Its shape is indeterminate, it can flow at will, and it is easy to be compressed. The molecular spacing of gas is quite large, and the interaction force is weak, so it can spread rapidly and fill the space it is placed in.
Water is a common liquid, and it is in a flowing state at room temperature. Its color is transparent, odorless, and odorless. Water has a certain viscosity and surface tension, which can make light objects float on it. The boiling point of water is 100 degrees Celsius, and the freezing point is zero degrees Celsius. The density of water is about one gram per cubic centimeter, and the density is maximum at 4 degrees Celsius. Because it is a good solvent, many substances can be dissolved in it.
Tetraaminosilane, if it is a solid, its texture may be hard or brittle. Generally speaking, its melting point is relatively high, and a certain amount of heat is required to melt it. The surface of tetraaminosilane may have a specific luster and texture, and the electrical conductivity and thermal conductivity also have their own characteristics, which vary according to its specific structure and purity.
Gas, water, and tetraaminosilane all exhibit different physical properties due to their different molecular structures and compositions, and each exhibits its unique state in the world.
What are the chemical properties of 1-chloro-2-fluoro-4-nitrobenzene?
1 + -Deuterium-2 + -tritium-4 + -aminopyridine, all three are chemical substances, each with its own unique characteristics.
Deuterium is a stable isotope of hydrogen. Its nucleus has more neutrons than ordinary hydrogen. The chemical properties of deuterium are similar to those of hydrogen, but they are slightly different in reaction rate due to mass differences. In many chemical reactions, deuterated compounds are often used as tracers to help chemists gain insight into the reaction mechanism. Due to its stability, it also has important uses in the field of nuclear physics. It is a key raw material for nuclear fusion reactions. It can fuse with tritium and release huge energy.
Tritium is also an isotope of hydrogen, but it is radioactive. Its nucleus contains one proton and two neutrons. The chemical properties of tritium are also similar to those of hydrogen, but its radioactivity limits its application. Tritium is extremely small in nature and is often artificially prepared. Tritium is used in military fields as an important raw material for the manufacture of hydrogen bombs. In scientific research, it is also used as a radioactive tracer to study biological, chemical and other processes.
4-aminopyridine is an organic compound. Its molecules contain pyridine rings and amino groups. 4-aminopyridine is basic because the amino group can bind protons. Its chemical properties are active and can participate in many organic reactions, such as nucleophilic substitution, acylation and other reactions. In the field of medicine, 4-aminopyridine shows unique medicinal value, can regulate nerve conduction, and has potential efficacy in the treatment of certain nervous system diseases.
In summary, although 1 + -deuterium-2 + -tritium-4 + -aminopyridine is a chemical substance, it plays an important role in scientific research, energy, medicine and other fields due to differences in structure and composition.
What are the synthesis methods of 1-chloro-2-fluoro-4-nitrobenzene?
To prepare 1-bromo-2-ethyl-4-aminobenzene, the following methods can be used:
First, take 2-ethyl-4-aminobenzene as the starting material and make it react with the bromine reagent under appropriate conditions. This reaction requires careful regulation of reaction conditions, such as temperature, solvent and catalyst. If the temperature is too high, polybromination by-products will be feared; if the temperature is too low, the reaction rate will be slow. Choosing a suitable solvent can help the reactants fully dissolve and stabilize the reaction intermediate. A suitable catalyst can improve the reaction efficiency and selectivity.
Second, the benzene ring can be appropriately modified first, and suitable groups can be introduced to construct the target structure through a series of reactions. For example, a guide group is introduced first to guide the precise positioning of bromine atoms, and then the guide group is removed or converted into the desired amino group. This strategy requires careful planning of reaction steps to ensure the smooth progress of each step and avoid by-products that are difficult to separate.
Third, learn from the previous experience in the synthesis of similar compounds to optimize and adjust the reaction route. Refer to relevant literature reports, according to the structural characteristics of the target compound, improve the reaction conditions, select high-efficiency reagents or catalysts, and improve the synthesis efficiency and yield.
When synthesizing this compound, it is necessary to pay attention to the precise control of reaction conditions to ensure that the proportion of reactants is appropriate, and appropriate separation and purification methods are used to obtain high-purity target products. At the same time, pay attention to experimental safety and properly dispose of toxic and harmful reagents and waste.
What should be paid attention to when storing and transporting 1-chloro-2-fluoro-4-nitrobenzene?
Mercury, lead, and tetraaminobiphenyl are all highly toxic and harmful substances. When storing and transporting, you need to pay great attention to the following points:
First, the storage must be carefully selected. Find a dry, cool, well-ventilated place, away from fire, heat, and direct sunlight. If these substances are heated or exposed to strong light, they may cause chemical reactions, causing their properties to change, increasing the risk of leakage and poisoning. And they should be separated from acids, bases, and other reactive substances to prevent interaction and formation of more dangerous substances.
Second, be sure to pack firmly and reliably. For mercury, it is usually packed in thick-walled glass containers or special metal containers, tightly sealed to ensure that there is no risk of leakage. Lead is mostly stored in blocks or ingots, and its packaging should also be able to prevent physical damage from exposing it. Tetraaminobiphenyl needs to be packaged in a well-sealed package to avoid oxidative deterioration due to contact with air. Key information such as the name of the substance, toxicity level, and warning labels should be clearly marked on the package for identification and prevention.
Third, the transportation process needs to strictly abide by regulations. Transport personnel should be professionally trained and familiar with the characteristics of such highly toxic substances and emergency disposal methods. Transportation vehicles need to have good protection and sealing measures, and they should travel slowly on the way to prevent bumps and collisions from causing package damage. At the same time, transportation routes should be planned in advance to avoid sensitive areas such as water sources and densely populated areas, and transportation-related information should be reported to relevant departments for supervision and emergency response.
Fourth, storage and transportation sites should be equipped with complete emergency rescue facilities and materials. Such as gas masks, protective clothing, leakage emergency treatment tools, etc. And formulate detailed emergency plans, organize regular drills, and in the event of leaks and other accidents, rescue operations can be carried out quickly and effectively to minimize the harm.