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1-Chloro-2,6-Difluorobenzene

1-Chloro-2,6-Difluorobenzene

Hongda Chemical

Specifications

HS Code

368569

Chemical Formula C6H3ClF2
Molar Mass 148.54 g/mol
Appearance Colorless liquid
Boiling Point 129 - 130 °C
Density 1.32 g/cm³
Solubility In Water Insoluble
Flash Point 32 °C
Odor Characteristic aromatic odor

As an accredited 1-Chloro-2,6-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - chloro - 2,6 - difluorobenzene in 500 - mL glass bottles, 10 bottles per carton.
Storage 1 - Chloro - 2,6 - difluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames as it is likely flammable. Keep it in a tightly closed container, preferably made of materials resistant to corrosion. Store separately from oxidizing agents and incompatible substances to prevent potential chemical reactions.
Shipping 1 - Chloro - 2,6 - difluorobenzene is shipped in specialized, corrosion - resistant containers. Packaging ensures no leakage during transit. Shipments follow strict chemical transportation regulations to maintain safety.
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1-Chloro-2,6-Difluorobenzene 1-Chloro-2,6-Difluorobenzene
General Information
Historical Development
1 - Chloro - 2,6 - Difluorobenzene is also a chemical product. Tracing the course of its research and development, in the past years, all kinds of scholars have devoted themselves to exploring this compound. At the beginning, the understanding was still shallow, and the synthesis method was difficult and complicated. However, scientific researchers are reluctant to study. After countless experiments, or adjusting the reaction conditions, or looking for novel raw materials, the synthesis method has gradually improved. With the passage of time, the technology continues to evolve, the preparation efficiency has been improved, and the purity of the product has also been improved. The difficulty of synthesis in the past has gradually changed into the order of production today. Looking at its historical development, it is like a long volume, written by the sweat and wisdom of researchers, from vague to clear, from difficult to smooth, the development of this chemical is a testament to the unremitting exploration in the field of chemistry.
Product Overview
1 - Chloro - 2,6 - Difluorobenzene is an organic compound, which is a colorless to light yellow liquid with a unique odor. This substance has a wide range of uses in the chemical industry. In pharmaceutical synthesis, it can be used as a key intermediate to help develop new drugs and contribute to human health. In the creation of pesticides, it can contribute to the synthesis of high-efficiency and low-toxicity pesticides to ensure the thriving growth of crops.
Its preparation process is complex and requires precise control. Usually, specific aromatics are used as the starting material and can be prepared after a series of reactions such as halogenation. The reaction conditions are harsh, and temperature, pressure and catalyst selection have a significant impact on the purity and yield of the product. From the perspective of chemical properties, the chlorine and fluorine atoms in this compound are unique and can participate in many substitution reactions to derive a variety of functional compounds, which greatly expands its application scope and occupies an important position in the field of modern organic synthetic chemistry.
Physical & Chemical Properties
1 - Chloro - 2,6 - Difluorobenzene is an organic compound, and its physicochemical properties are very important. Looking at its physical properties, at room temperature, this substance is mostly a colorless to light yellow liquid with a unique odor. Its boiling point is about [X] ° C, its melting point is [X] ° C, and its density is [X] g/cm ³. Under certain conditions, it has good volatility. When it comes to chemical properties, its chemical activity is considerable because it contains chlorine and fluorine atoms. Chlorine atoms can participate in nucleophilic substitution reactions, while fluorine atoms enhance the stability and electronegativity of molecules. Under appropriate reaction conditions, 1-Chloro-2,6-Difluorobenzene can react with many reagents, such as co-heating with alkali, chlorine atoms may be replaced by hydroxyl groups; in case of nucleophiles, or initiate corresponding substitution reactions to generate various derivatives. With its physicochemical properties, 1-Chloro-2,6-Difluorobenzene is widely used in the field of organic synthesis.
Technical Specifications & Labeling
1 - Chloro - 2,6 - Difluorobenzene is an important chemical raw material. Its technical specifications and identification (product parameters) are extremely critical. As far as technical specifications are concerned, the purity should be strictly controlled, and the impurity content should be above [X]%, and the impurity content must be lower than [specific value]. Its appearance should be a colorless and transparent liquid, and the smell should not be abnormally pungent.
In terms of identification, the product label should clearly mark the name of "1 - Chloro - 2,6 - Difluorobenzene", indicating the manufacturer, production date, batch and other information. At the same time, warning signs, such as flammable and harmful labels, should be posted in accordance with relevant laws and regulations to ensure that users can clearly understand their characteristics and potential hazards, so as to standardize production and use, and ensure the safety of all parties and product quality.
Preparation Method
1 - Chloro - 2,6 - Difluorobenzene is an important chemical raw material, and its preparation method is crucial.
The raw material for preparation often takes specific aromatic hydrocarbons, supplemented by chlorine and fluorine-containing reagents. The production process is based on the halogenation reaction of aromatic hydrocarbons. First, the aromatic hydrocarbons and chlorine-containing reagents are co-placed in a specific reactor, controlled at a suitable temperature and pressure to initiate a substitution reaction, and chlorine atoms are introduced at a specific position in the benzene ring.
Then, fluorine-containing reagents are added and the reaction is sequenced. This step requires precise regulation of reaction conditions, such as reaction time, pH, etc., so that fluorine atoms can smoothly replace hydrogen atoms in the corresponding positions of the benzene ring, and finally 1 - Chloro - 2,6 - Difluorobenzene is obtained
In order to ensure the purity of the product, a perfect purification mechanism needs to be established. By distillation, extraction and other means, unreacted raw materials and by-products are removed to obtain high-purity target products. In this way, 1-Chloro-2,6-Difluorobenzene with good quality can be obtained.
Chemical Reactions & Modifications
Today there is a product named 1 - Chloro - 2,6 - Difluorobenzene. In the field of chemistry, its reaction and modification are quite important to our generation.
To make this product, we often go through several reactions. The method of the past may be complicated and inefficient. In order to improve, we have dedicated ourselves to research, hoping to optimize the reaction path and improve the yield and purity.
The way of its modification is related to the change of molecular structure. Or add groups or bond regulation to give it new energy. If a specific functional group is introduced, it can be used in a specific reaction to show different activities and is suitable for multiple fields.
After repeated trials, the improved method is gradually becoming apparent. Under the new approach, the reaction rate is increased, the side effects are less, and the quality of the product is also excellent. This is good news in the chemical industry, paving the way for subsequent research and use, so that the effect of 1-Chloro-2,6-Difluorobenzene can be further extended.
Synonyms & Product Names
1 - Chloro - 2,6 - Difluorobenzene is an important chemical substance. Its synonyms and trade names are really related to the identification and application in the chemical industry.
Looking at this substance, different names have their own uses in chemical research and production. For the convenience of academic inquiry and communication, chemists have given many aliases according to its chemical structure and properties. For example, from the perspective of structure, or there are aliases named after its atomic connection, so that scholars can express it accurately when discussing.
As for product names, they mostly focus on marketing activities and applications. If merchants want to make their products stand out, they will use distinctive product names. Either highlight its high purity, or highlight its specific use to attract customers. Although the two are different in title, they all revolve around the essential characteristics of 1-Chloro-2,6-Difluorobenzene, and are indispensable in chemical research and development, trade and other links.
Safety & Operational Standards
1 - Chloro - 2,6 - Difluorobenzene is an important chemical product, which is crucial to its safety and operating practices.
This product has certain chemical activity. When storing, it must be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources and prevent direct sunlight. Packaging should be well sealed to prevent leakage. Because it may react with certain substances, it should not be mixed with oxidants, alkalis, etc. to avoid danger.
During operation, operators must undergo special training and strictly follow the operating procedures. It is recommended that operators wear self-priming filter gas masks (half masks), chemical safety glasses, anti-poison infiltration work clothes, and rubber oil-resistant gloves to ensure their own safety. The operation should be carried out in a fume hood to avoid steam leakage into the air of the workplace.
If a leak occurs accidentally, personnel from the leaking contaminated area should be quickly evacuated to a safe area, and quarantined to strictly restrict access. Cut off the source of fire. It is recommended that emergency personnel wear self-contained positive pressure breathing apparatus and anti-poison clothing. Cut off the source of leakage as much as possible. Prevent it from flowing into restricted spaces such as sewers and flood drains. Small leakage: adsorb or absorb with sand or other non-combustible materials. It can also be scrubbed with an emulsion made of non-combustible dispersant, and the lotion is diluted and placed into the wastewater system. Large number of leaks: build a dike or dig a pit to contain. Transfer to a tanker or special collector by pump, recycle or transport to a waste disposal site for disposal.
Only by strictly adhering to safety and operating practices can the safety of 1-Chloro-2,6-Difluorobenzene be ensured during production, storage and use, to avoid accidents, and to ensure the safety of people and the environment.
Application Area
1 - Chloro - 2,6 - Difluorobenzene is an organic compound, which is widely used in many fields of chemical industry. It can be used as an intermediate in pharmaceutical synthesis, such as the preparation of certain antibacterial drugs, which helps to precisely combat bacteria and protect human health. In the field of pesticides, this raw material can create high-efficiency insecticides, protect crops from insect pests, and improve food production.
It also has outstanding performance in the field of materials science. It can participate in the synthesis of high-performance engineering plastics, making plastic products have better mechanical properties and chemical stability, and plays a key role in automotive manufacturing, electronic equipment and other industries. It can also be used as an important starting material for dye synthesis, giving dyes excellent color fastness and vividness, and is widely used in textile printing and dyeing industry.
With its unique chemical structure, this compound has shown important value in multiple application fields, promoting the continuous progress of chemical and related industries.
Research & Development
Today there is 1 - Chloro - 2,6 - Difluorobenzene, which is of great value for research and development in the field of chemical research in China. Its unique properties and exquisite structure may emerge in various fields such as medicine and materials.
Our researchers should carefully study its synthesis method, strive to improve the process, improve the yield, and strictly control impurities. Observe its reaction mechanism and explore the way to optimize, hoping to reduce costs and improve efficiency.
Furthermore, explore its interaction with other substances, or discover new characteristics and uses. This material holds great potential for future development. We should make unremitting efforts to promote its wide application, contribute to scientific progress and social development, and promote the continuous progress of this field. In the process of research and development, we will achieve fruitful results.
Toxicity Research
The toxicity of 1-Chloro-2,6-Difluorobenzene is studied. This compound is very important in the field of chemical industry.
The physicochemical properties of this compound were initially observed, and its shape, taste, melting point, etc., were all related to toxicity. During the experiment, try it with various creatures. Look at white pigs, guinea pigs, etc., fed with food containing this substance, or exposed to its volatile gas.
Not long ago, white pigs were hyperactive and restless, their diet gradually decreased, and their fur lost its luster. Guinea pigs occasionally suffered from asthma and coughing, and their lungs seemed to be disturbed by it. After analysis, this substance entered the body, or broke the membrane of the cell, and disrupted the order of metabolism.
From this point of view, 1 - Chloro - 2,6 - Difluorobenzene is toxic and harmful to the health of living beings. Use it in the future with caution to prevent its escape, to ensure the safety of all living beings, and to protect the environment.
Future Prospects
In the future, I have researched 1 - Chloro - 2,6 - Difluorobenzene, and the prospect is clear. This compound has many properties, its characteristics are special, and it can be used for innovation in multiple domains.
In research and development, it may become the cornerstone of new types of products, and its characteristics can help those who overcome diseases and save people. In the field of materials, it may lead to the generation of new materials, improve performance, and make equipment refined, which can be used in aerospace, aircraft, etc.
In the process of engineering, it is expected to improve and improve, reduce costs and increase efficiency, and promote the development of chemical industry. Our scientific researchers, we will take it, investigate its secrets, and make it benefit the world. In the future, it will be a great engine for technological progress, adding to human well-being.
Where to Buy 1-Chloro-2,6-Difluorobenzene in China?
As a trusted 1-Chloro-2,6-Difluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Chloro-2,6-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Chloro-2,6-Difluorobenzene?
1-Chloro-2,6-difluorobenzene is also an organic compound. It has a wide range of uses and has important applications in many fields.
In the field of pharmaceutical synthesis, 1-chloro-2,6-difluorobenzene is often a key intermediate. Through a series of chemical reactions, it can be converted into drug molecules with complex structures. Taking some antibacterial drugs as an example, the special chemical structure of 1-chloro-2,6-difluorobenzene allows it to participate in specific reaction steps and contribute to the construction of compounds with antibacterial activity, contributing to the research and development of medicine.
It also plays an important role in the preparation of pesticides. Pesticides are designed to control crop diseases and insect pests and ensure agricultural production. 1-chloro-2,6-difluorobenzene can be used as a starting material, chemically modified and transformed to produce pesticide products with high insecticidal, bactericidal or herbicidal properties. Due to its unique chemical properties, it can give pesticides better biological activity and environmental adaptability, and is indispensable in modern agricultural production.
In addition, in the field of materials science, 1-chloro-2,6-difluorobenzene is also used. In the synthesis process of some high-performance polymer materials, it can be used as a modified monomer or auxiliary agent. By introducing this compound, the properties of polymers can be improved, such as improving their heat resistance and chemical corrosion resistance, and then broadening the application range of polymer materials in special environments, such as aerospace, electronics industry and other fields that require strict material properties.
In short, although 1-chloro-2,6-difluorobenzene is an organic compound, it is widely used and critical in many fields such as medicine, pesticides and materials science, and is of great significance to promote the development of related industries.
What are the physical properties of 1-Chloro-2,6-Difluorobenzene?
1-Chloro-2,6-difluorobenzene is also an organic compound. It has unique physical properties, let me tell you one by one.
First of all, its properties are mostly colorless to light yellow transparent liquids at room temperature, which are clear in appearance and free of impurities.
The second time and its boiling point are about 148-150 ° C. At this temperature, the substance gradually changes from liquid to gaseous state. This boiling point value is quite critical when separating and purifying this compound.
Furthermore, its melting point is about -22 ° C. When the temperature drops to this temperature, the substance will condense from liquid to solid, and this property is also taken into account when storing and transporting.
In terms of density, it is about 1.38 g/cm ³, which is heavier than water, so if mixed with water, it will sink to the bottom.
In terms of solubility, it is slightly soluble in water, but it can be miscible with many organic solvents, such as ethanol, ether, acetone, etc. This solubility characteristic makes it an excellent reaction medium in the field of organic synthesis, assisting the progress of various chemical reactions.
In terms of volatility, it has a certain degree of volatility and can slowly evaporate into the air in an exposed environment. Therefore, when storing, it needs to be properly sealed to prevent volatilization loss, and because of its certain irritation, volatilization in the air may also affect the environment and human health.
The physical properties of 1-chloro-2,6-difluorobenzene are of great significance in the application of chemical, pharmaceutical, pesticide and other industries, and are the basis for many related operations and reactions.
Is 1-Chloro-2,6-Difluorobenzene Chemically Stable?
The chemical stability of 1-chloro-2,6-difluorobenzene is related to many reasons. This substance has the characteristics of halogenated aromatics, and the substitution of chlorine atoms and difluorine atoms has a great influence on its properties.
First talk about its stability. Halogenated aromatics have certain chemical stability. For 1-chloro-2,6-difluorobenzene, the conjugate system of the benzene ring makes its structure inherently stable. When fluorine atoms and chlorine atoms are connected to the benzene ring, the electron cloud density distribution of the benzene ring can be changed by induction and conjugation effects. Fluorine atoms are particularly high electronegativity, strong electron-absorbing induction effect, resulting in a decrease in the electron cloud density of the benzene ring, making it difficult for electrophilic substitution reactions to occur and increasing their stability to a certain extent.
However, from another perspective, halogen atoms can make this substance reactive. Under appropriate conditions, chlorine atoms can be replaced by nucleophiles. For example, in the case of strong nucleophiles, such as sodium alcohols, amines, etc., chlorine atoms can undergo nucleophilic substitution reactions to generate corresponding substitution products. This is because chlorine atoms can leave with a pair of electrons, leaving a carbon positive ion intermediate, and nucleophiles attack this intermediate.
Furthermore, in some specific reaction environments, such as high temperature, light or the presence of catalysts, 1-chloro-2,6-difluorobenzene can also participate in the reaction. Under light, free radical reactions may be initiated; under high temperature and suitable catalysts, halogen atoms on the benzene ring can participate in rearrangements and other reactions.
Overall, 1-chloro-2,6-difluorobenzene has certain chemical stability at room temperature and pressure without special reagents or conditions; however, under specific reaction conditions and reagents, it can still exhibit chemical activity and various reactions occur. It is not possible to generalize it simply as stable or unstable.
What is the production process of 1-Chloro-2,6-Difluorobenzene?
1-Chloro-2,6-difluorobenzene is an important raw material in organic synthesis. Its preparation process is delicate and complex, requiring many steps and suitable conditions.
The first is the choice of starting materials, often based on compounds containing benzene rings, such as specific halogenated benzene. Through a series of reactions, chlorine and fluorine atoms are introduced to form the target product.
Halogenation is a key step. To introduce chlorine atoms, you can use chlorine gas or chlorine-containing reagents to react with the substrate in a suitable reaction system. This process requires fine regulation of reaction temperature, pressure and catalyst. If the temperature is too high, or side reactions are clustered, and the product is impure; if the temperature is too low, the reaction rate is slow and time-consuming. The pressure also needs to be considered, and the appropriate pressure can promote the positive progress of the reaction. The choice of catalyst has a great impact on the reaction rate and selectivity. Specific metal halide or other catalytic substances can effectively improve the reaction efficiency.
Fluorination reactions are also challenging. Fluorinated reagents, such as potassium fluoride, are usually used. This reaction often needs to be carried out in special solvents to ensure the solubility and reactivity of the reagents. The polarity and boiling point of the solvent are all related to the reaction process. In addition, the anhydrous environment during the reaction is very important, and moisture or reagent failure can interfere with the reaction.
Separation and purification steps should not be ignored. After the reaction, the product may contain impurities such as unreacted raw materials and by-products. Distillation, extraction, crystallization and other methods are required to remove impurities and obtain pure 1-chloro-2,6-difluorobenzene. Distillation separates according to the difference in boiling point of each component; extraction uses the different solubility of solutes in different solvents; crystallization controls the temperature and solvent ratio to crystallize the product.
The process of preparing 1-chloro-2,6-difluorobenzene requires precise control of each reaction step and consideration of many factors to obtain high-quality products to meet the needs of chemical, pharmaceutical and other industries.
What are the precautions for storing and transporting 1-Chloro-2,6-Difluorobenzene?
1-Chloro-2,6-difluorobenzene is also an organic compound. During storage and transportation, many matters must not be ignored.
First word storage. This substance should be stored in a cool, dry and well-ventilated place. Cover it or have certain volatility and chemical activity, warm and humid places, easy to cause deterioration or chemical reactions. If placed in a high temperature environment, the molecular movement will increase, or its stability will be damaged. Therefore, it is necessary to keep the storage place with moderate temperature and appropriate humidity.
Furthermore, the storage place should be away from fire and heat sources. Because of its flammability, in case of open flames and hot topics, there is a risk of combustion and explosion. And it should be stored separately from oxidants, acids, alkalis, etc., and must not be mixed. Due to its active chemical properties, it encounters with various substances or reacts violently, endangering safety.
As for transportation, caution is also required. Transportation vehicles must ensure that the vehicle is in good condition and has perfect protective measures. When loading, it should be placed firmly to prevent collisions, drops, package damage, and material leakage. During transportation, drivers should always pay attention to road conditions and vehicle conditions, and avoid violent operations such as sudden braking and sharp turns. And during transportation, smoking is strictly prohibited to prevent all behaviors that may cause ignition.
In addition, whether it is storage or transportation, professional training is required for relevant personnel to familiarize them with the characteristics and safety precautions of 1-chloro-2,6-difluorobenzene. In the event of an unexpected situation such as leakage, it should be able to be disposed of quickly and properly to reduce the harm. In this way, the safety of 1-chloro-2,6-difluorobenzene during storage and transportation can be guaranteed.