1-Chloro-2,4-Difluorobenzene

Hongda Chemical

Specifications

HS Code	486448
Chemical Formula	C6H3ClF2
Molar Mass	148.54 g/mol
Appearance	Colorless liquid
Boiling Point	124 - 126 °C
Density	1.327 g/cm³
Solubility	Insoluble in water, soluble in organic solvents
Flash Point	28 °C
Odor	Typical aromatic - halogenated odor

As an accredited 1-Chloro-2,4-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	1 - chloro - 2,4 - difluorobenzene packaged in 5 - liter containers.
Storage	1 - Chloro - 2,4 - difluorobenzene should be stored in a cool, well - ventilated area, away from heat and ignition sources. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials due to its chemical nature. Store it separately from oxidizing agents and reactive substances to prevent potential chemical reactions.
Shipping	1 - Chloro - 2,4 - difluorobenzene is shipped in well - sealed, corrosion - resistant containers. Special care is taken to comply with hazardous chemical shipping regulations, ensuring safe transport to prevent leaks and potential environmental or safety risks.

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General Information

Historical Development

1 - Chloro - 2,4 - Difluorobenzene is an organic compound. It originated from the unremitting research of chemists in the past. At that time, the science of chemistry was in the ascendant, and all the sages wanted to explore the wonderful principles of material change.
At the beginning, everyone explored the field of organic synthesis and moved forward. After countless attempts, they gradually obtained the method of preparing this compound. Start with basic raw materials, and gradually build its molecular structure through chemical reactions such as substitution and addition. Although the process is difficult and sometimes fails, chemists uphold perseverance and eventually achieve success.
With the passage of time, the technology continues to improve, the method of preparing 1-Chloro-2,4-Difluorobenzene is becoming more and more mature, and the yield is gradually increasing. This compound has emerged in many fields such as medicine and materials, and has made great contributions to the development of mankind. Therefore, its historical evolution is a vivid portrayal of the development of chemistry.

Product Overview

1 - Chloro - 2,4 - Difluorobenzene is an important chemical substance. It is a colorless to light yellow liquid with a special odor. This substance is widely used in the chemical industry and is often a key intermediate in the synthesis of many fine chemicals.
Its preparation is mostly through a specific chemical reaction process. Using benzene as the starting material, this product can be obtained through a series of precisely controlled reaction steps such as halogenation. The control of reaction conditions is extremely important, such as temperature, choice and dosage of catalyst, which have a profound impact on the purity and yield of the product.
1 - Chloro - 2,4 - Difluorobenzene has stable physical and chemical properties, but it will also react with certain substances under specific environments. Because of its chlorine and fluorine atoms, it has unique chemical activities and can play an important role in organic synthesis, assisting in the preparation of various organic compounds with unique functions, making significant contributions to the development of the chemical industry.

Physical & Chemical Properties

1 - Chloro - 2,4 - Difluorobenzene is an organic compound. It is a colorless liquid with a special odor. Looking at its physical properties, the boiling point is appropriate, and it can exist stably under normal temperature and pressure. Its density is also fixed, which is related to its floating and sinking in different media.
In terms of its chemical properties, the existence of chlorine and fluorine atoms gives it a unique reactivity. The high electronegativity of fluorine atoms makes the molecular electron cloud different, and it is easy to lead to electrophilic or nucleophilic reactions. Chlorine atoms are also active check points for reactions and can participate in various reactions such as substitution. In the field of organic synthesis, it is often an important intermediate, capable of generating a variety of compounds through various reaction pathways, and has considerable application value in the pharmaceutical, pesticide and other industries.

Technical Specifications & Labeling

1 - Chloro - 2,4 - Difluorobenzene is an important chemical product. Its process specifications and identification (product parameters) are related to production and application. Looking at this product, the process specifications need to be precisely controlled. The ratio of chlorine and fluorine elements and the reaction conditions are all key. The reaction temperature should be stabilized in a specific range to ensure the purity of the product.
identification (product parameters) cannot be ignored. From appearance and color to chemical purity, it needs to be clearly marked. The appearance of this product should have specific characteristics, and the chemical purity must meet the specified standards. In this way, it is qualified 1 - Chloro - 2,4 - Difluorobenzene, which can be properly applied in various fields of chemical industry and help industrial production and scientific research.

Preparation Method

1 - Chloro - 2,4 - Difluorobenzene is an important chemical raw material. Its preparation method, raw materials and production process are very important.
To make this product, a specific aromatic hydrocarbon is often used as the initial raw material. First, chlorine atoms and fluorine atoms are introduced through a halogenation reaction. This reaction requires precise temperature control and the help of a catalyst to make the reaction proceed in the expected direction.
In the reaction step, the aromatic hydrocarbon is placed in a specific reactor, an appropriate amount of halogenating reagent is added, and it is fully reacted at a suitable temperature and pressure. When the reaction is initially formed, the product still contains impurities and needs to be separated and purified.
As for the catalytic mechanism, the selected catalyst can effectively reduce the activation energy of the reaction, accelerate the reaction process, and improve the yield and purity of the product. The commonly used catalyst has the characteristics of high efficiency and stability, which can ensure the stable progress of the reaction. In this way, 1-Chloro-2,4-Difluorobenzene of high quality can be prepared.

Chemical Reactions & Modifications

1 - Chloro - 2,4 - Difluorobenzene is an important compound in organic synthesis. In its chemical reaction, we need to study its chemical response and modification in detail. In past experiments, it was found that when it reacted with nucleophiles, chlorine atoms were often replaced first because of their higher activity. However, in order to involve fluorine atoms in the reaction, more stringent conditions are required. To optimize its reactivity, specific groups can be introduced to adjust the electron cloud distribution. In this way, its reactivity and selectivity may be changed. For example, adding a power supply group to the benzene ring can enhance the activity of fluorine atoms, which is conducive to the nucleophilic substitution reaction. This is also a key strategy for modification. The application of 1-Chloro-2,4-Difluorobenzene in more fields may be expanded through in-depth investigation of such chemical response and modification methods.

Synonyms & Product Names

1 - Chloro - 2,4 - Difluorobenzene is also a chemical substance. There are many synonyms, each of which refers to the specific compound. This compound is also known in the industry and has various trade names.
Synonyms refer to the same substance in different words. Such as the name set by the chemical nomenclature, and the usual name, although the text is different, in fact it refers to nothing. 1 - Chloro - 2,4 - Difluorobenzene Synonyms, or according to its structural characteristics, or according to its nature and use.
As for the trade name, the manufacturer gives it a unique name to identify its own product. The trade names of different manufacturers may be different, but they all revolve around the essence of 1-Chloro-2,4-Difluorobenzene. Knowing its synonyms and trade names is of great benefit to chemical research and production practice. It can be seen that under different names, they are actually the same substance, so as to avoid confusion, so as to facilitate communication and promote the development of the chemical field.

Safety & Operational Standards

1 - Chloro - 2,4 - Difluorobenzene is an important chemical product. It is extremely important for its safety and operation specifications.
This chemical is dangerous. When storing, it should be placed in a cool and well-ventilated place. Keep away from fire and heat sources to prevent accidents. It should be stored separately from oxidants, alkalis, etc., and must not be mixed to avoid violent reactions.
During operation, operators must undergo special training and strictly abide by operating procedures. It is recommended that operators wear self-priming filter gas masks (half masks), chemical safety glasses, anti-poison penetration overalls, and rubber oil-resistant gloves to ensure their own safety.
When retrieving and transferring the chemical, extreme care should be taken to prevent it from leaking into the environment. In the unfortunate event of a leak, personnel from the contaminated area of the leak should be quickly evacuated to a safe area and quarantined, and access should be strictly restricted. Emergency personnel need to wear appropriate protective equipment and do not allow the leak to come into contact with combustible substances (such as wood, paper, oil, etc.). In the event of a small leak, it can be adsorbed or absorbed by sand or other non-combustible materials. In the case of a large leak, it is necessary to build an embankment or dig a pit to contain it, cover it with foam to reduce steam disasters, and then transfer it to a tanker or a special collector with a pump for recycling or transportation to a waste treatment site for disposal.
In conclusion, every step in the safety and operation of 1-Chloro-2,4-Difluorobenzene should not be taken lightly, so as to ensure the safety of personnel and the environment is not contaminated.

Application Area

1 - Chloro - 2,4 - Difluorobenzene is an important chemical substance with a wide range of application fields. In the field of pharmaceutical synthesis, it is often a key intermediate for the preparation of specific drugs. Due to its unique chemical structure, it can participate in a variety of organic reactions, help build complex drug molecular structures, and then play an important role in the treatment of diseases.
In the field of materials science, this substance also shows unique value. It can be used to develop new materials with special properties, such as some high-performance polymer materials. After rational chemical modification and polymerization, the special properties of 1-Chloro-2,4-Difluorobenzene can endow materials with higher stability, excellent electrical conductivity or unique optical properties, injecting new vitality into the development of materials science.
In the development of pesticides, its application cannot be ignored. It can be used as an important raw material for the synthesis of high-efficiency and low-toxicity pesticides. Through precise chemical design and synthesis paths, pesticide products with strong targeted killing effect on pests and low impact on the environment can be prepared, providing support for the sustainable development of agriculture.

Research & Development

In recent years, I have had some experience in the research of 1-Chloro-2,4-Difluorobenzene. This compound has special properties and has great potential in the field of organic synthesis.
At the beginning, its structure was studied in detail, the characteristics of its chemical bonds were explored, and its activity check point was known. Then, study various synthesis methods, or choose the raw materials that are easy to obtain, the steps are simple, or the yield is excellent and the purity is high.
During the experiment, the effects of reaction conditions, such as temperature, pressure, and the amount of catalyst, were carefully regulated. After repeated attempts, the method of optimization was gradually obtained, and the yield was also steadily improved.
Looking forward to the future, I hope to expand its application scope. In the creation of medicine, it may become a key intermediate to help the research and development of new pharmaceuticals; in material science, or give materials unique properties, and create a new chapter of materials. With unremitting efforts, we hope to promote the research and development of 1-Chloro-2,4-Difluorobenzene, and contribute to the academic community.

Toxicity Research

1 - Chloro - 2,4 - Difluorobenzene is a chemical substance, and its toxicity study is crucial. The toxicity of this substance is studied in detail today.
After various experiments, 1 - Chloro - 2,4 - Difluorobenzene has a certain effect on organisms. In animal experiments, if exposed to this substance, some tested animals will experience adverse reactions. There may be signs of organ damage, such as liver and kidney function or abnormalities.
And observing its effect on cells, it can also interfere with the normal metabolism of cells or cause cell lesions. However, the exact mechanism of its toxicity needs to be further studied.
Although some discoveries have been made, extensive data collection and in-depth investigation are still needed to clarify the toxicity of 1-Chloro-2,4-Difluorobenzene in different environments and at different doses. The road to this research is long, and only by unremitting research can we fully understand the toxicity mystery of 1-Chloro-2,4-Difluorobenzene and provide a solid basis for protection and application.

Future Prospects

In the future world, science and technology are changing day by day, and chemical products will also have great benefits. 1 - Chloro - 2,4 - Difluorobenzene This product has already realized its unique properties. In the synthesis of natural materials, it is often used as a raw material, and it is used to create things and other materials.
Looking forward to the future, its use will be more effective. Or it can help research new special effects, which can solve the suffering of the world; for the problem, it can also create high-efficiency and low-toxicity products, so that the crops can be harvested and the food can be kept safe. And its synthesis method is increasingly exquisite, saving more energy and less dyeing, which is suitable for the idea of protection. This is the hope of our chemical researchers, hoping that 1-Chloro-2,4-Difluorobenzene will be widely used and benefit the people.

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Frequently Asked Questions

As a leading 1-Chloro-2,4-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Chloro-2,4-Difluorobenzene?

1-Chloro-2,4-difluorobenzene is also an organic compound. It has a wide range of uses and is used in various fields of chemical industry.
First, it is often a key intermediary in the synthesis of medicine. To create a cover medicine, it is necessary to use various organic compounds as the basis and undergo complex reactions to obtain the required drug ingredients. 1-Chloro-2,4-difluorobenzene can participate in many reactions due to its unique chemical structure, helping to form a specific molecular structure, laying the foundation for the synthesis of drugs with specific curative effects. For example, in the synthesis path of some antibacterial and antiviral drugs, its shadow is common, and the active ingredients of the drug are gradually constructed by ingenious reactions with other reagents.
Second, it is also an important raw material for the preparation of pesticides. In today's agriculture, pesticides are indispensable for ensuring crop harvest and preventing the invasion of diseases and pests. 1-Chloro-2,4-difluorobenzene can be converted into pesticide products with high insecticidal, bactericidal or herbicidal properties through a series of chemical reactions. After delicate chemical modification, it can precisely act on pests, while minimizing the adverse effects on crops and the environment, contributing to the sustainable development of agriculture.
Third, it also has its uses in the field of materials science. For example, in the synthesis of special polymer materials, 1-chloro-2,4-difluorobenzene can be introduced into the polymer chain as a modified monomer to improve the properties of the material. Or enhance its heat resistance, so that the material can still maintain stable physical and chemical properties in high temperature environments; or improve its chemical resistance, so that the material can resist the erosion of more chemical substances, so as to expand the application range of materials, in aerospace, electronics and other fields that require strict material properties.
In short, although 1-chloro-2,4-difluorobenzene is an organic compound, it plays an indispensable role in many key fields such as medicine, pesticides, and materials, promoting technological progress and industrial development in various fields.

What are the physical properties of 1-Chloro-2,4-Difluorobenzene?

1-Chloro-2,4-difluorobenzene is also an organic compound. It has special physical properties, related to chemical, pharmaceutical and other fields, and is quite important.
First of all, its properties, under room temperature, 1-chloro-2,4-difluorobenzene is a colorless to light yellow liquid, which is clear and transparent in appearance, like Liquan. Its smell is unique and has a fragrant charm, but this fragrance is not pleasant. It is slightly irritating, and the smell is pungent. The smell should be careful.
Times and boiling point, the boiling point of this substance is about 138-140 ° C. The boiling point is the temperature limit of the substance from liquid to gas state. When the temperature rises to the S value, 1-chloro-2,4-difluorobenzene molecules are energized, break free from each other, and rise into a gaseous state.
Furthermore, the melting point is about -44 ° C. The melting point is the critical temperature for solid to liquid state. Below this value, 1-chloro-2,4-difluorobenzene is in a solid state, like hard ice; above this value, it gradually melts into a liquid.
When it comes to density, it is about 1.388g/cm ³. Density, the mass of a substance per unit volume. It is heavier than water. If mixed with water, it will sink to the bottom of the water, such as a stone entering the water.
In terms of solubility, 1-chloro-2,4-difluorobenzene is slightly soluble in water, just like oil floats in water, and the two are difficult to melt. However, it is soluble in many organic solvents, such as ethanol, ether, acetone, etc. When it dissolves, it is like water and milk, regardless of each other. Because its molecular structure is similar to that of organic solvents, it is similar to that of dissolves.
Volatility, 1-chloro-2,4-difluorobenzene has a certain volatility. In an open environment at room temperature, the molecules escape in the air and gradually decrease. This property should be paid attention to when storing and using. When sealed, it should be stored to prevent its volatilization loss and avoid environmental hazards and personal injury caused by its volatilization.
1-chloro-2,4-difluorobenzene has unique physical properties. It is used as a raw material or intermediate in chemical synthesis and is involved in drug research and development in the field of medicine. All the properties lay the foundation for its application, and also provide the basis for users to understand its characteristics and safe operation.

What is the production method of 1-Chloro-2,4-Difluorobenzene?

1-Chloro-2,4-difluorobenzene is also an organic compound. The method of its preparation has been explored in the past, and the common methods described in the present are as follows.
First, 2,4-difluoroaniline is used as the starting material. First, it is combined with sodium nitrite and hydrochloric acid, and the reaction of diazotization is carried out at low temperature. This step can obtain 2,4-difluoro diazobenzene hydrochloride. Then, this salt is mixed with a hydrochloric acid solution of cuprous chloride, and it is heated to react. The diazo group is then replaced by a chlorine atom to obtain 1-chloro-2,4-difluorobenzene. Although this step is complicated, the raw material is easy to obtain and the reaction is controllable, which is a common way.
Second, 2,4-difluorobenzoic acid is used as the starting material. First, it is converted into an acid chloride, which is often achieved by reagents such as thionyl chloride. The obtained acid chloride is then reacted with ammonia water to obtain an amide. Subsequently, the amide is degraded by Hoffmann, that is, in the presence of bromine and alkali, the carbonyl group of the amide is removed, and the substituent on the nitrogen is rearranged to form a primary amine with one less carbon atom. Finally, this primary amine can be prepared by diazotization and chlorination as before.
Third, m-difluorobenzene is used as the raw material. M-difluorobenzene and chlorine are chlorinated in the presence of specific catalysts, such as iron powder or ferric chloride. In this reaction, chlorine atoms selectively replace hydrogen at specific positions on the benzene ring to obtain 1-chloro-2,4-difluorobenzene. The raw materials in this way are simple, but the selectivity of the reaction needs to be carefully adjusted to obtain high-purity products.
There are various methods for preparing 1-chloro-2,4-difluorobenzene, each with advantages and disadvantages. In actual preparation, when the availability of raw materials, cost, product purity requirements and other factors, choose carefully.

What are the precautions for storing and transporting 1-Chloro-2,4-Difluorobenzene?

1-Chloro-2,4-difluorobenzene is also an organic compound. During storage and transportation, many matters must not be ignored.
When storing, the first environment. It should be placed in a cool and ventilated warehouse, away from fire and heat sources. The cover is easy to cause danger due to the heat of this substance. In case of open flame, it may cause combustion or even explosion. The temperature of the warehouse should also be strictly controlled, generally not exceeding 30 ° C, in order to prevent its volatilization from intensifying and increasing the risk factor.
Furthermore, the compound needs to be stored in isolation from oxidants, alkalis, etc., and must not be stored mixed. Due to its active chemical properties, it can meet with oxidants or cause severe chemical reactions; contact with alkalis may also cause adverse consequences. At the same time, the warehouse must be equipped with suitable materials to contain leaks. Once a leak occurs, it can be properly handled in time to avoid the spread of harm.
As for transportation, the carrier must ensure that the vehicle is in good condition and has corresponding safety facilities. During transportation, the speed should not be too fast to prevent bumps and collisions from causing damage to the container and causing leakage. Escort personnel must also be present throughout the process to pay close attention to the transportation status.
Packaging is also crucial. It must be tightly sealed to ensure that there is no risk of leakage. Packaging materials should have good corrosion resistance and can resist the erosion of 1-chloro-2,4-difluorobenzene.
In short, all aspects of the storage and transportation of 1-chloro-2,4-difluorobenzene must be treated with caution. A little carelessness can lead to serious disasters, endangering personnel safety and the environment.

What is the market price trend of 1-Chloro-2,4-Difluorobenzene?

1-Chloro-2,4-difluorobenzene, this substance is widely used in the field of chemical industry, involving medicine, pesticides, materials and other industries. Its market price trend is related to many factors, complex, just like the changing situation, it is difficult to hide it.
The first to bear the brunt is the cost of raw materials. 1-Chloro-2,4-difluorobenzene is made of fluorobenzene, chlorine gas, etc. If the price of these raw materials fluctuates, it will affect the whole body, causing the price of 1-chloro-2,4-difluorobenzene to fluctuate. If the supply of fluorobenzene tightens and the price rises, the production cost of 1-chloro-2,4-difluorobenzene will rise, and its price will also rise.
The state of supply and demand in the market is also the key. If the pharmaceutical and pesticide industries are booming, the demand for 1-chloro-2,4-difluorobenzene will increase sharply, and when the supply is in short supply, the price will rise; conversely, if the industry is sluggish, the demand will drop sharply, and the supply will exceed the demand, the price will fall.
Furthermore, the impact of policies and regulations cannot be ignored. With stricter environmental protection policies, production enterprises need to invest more funds in environmental protection facilities, which will increase the cost of compliance operations, or cause product prices to rise; and changes in trade policies, tariff adjustments, import and export restrictions, etc., will also affect their market prices.
Technological innovation also affects prices. If the new production process can reduce costs and increase efficiency, increase production capacity, increase market supply, and prices may be suppressed; on the contrary, technology is stagnant, costs are difficult to drop, and prices are easy to firm.
In the past few years, the price of 1-chloro-2,4-difluorobenzene fluctuated. Market conditions and various factors are intertwined, causing prices to rise and fall from time to time. However, overall, under the dual effects of demand growth and cost changes, there is an upward trend. In the future, its prices will continue to fluctuate with changes in raw materials, supply and demand, policies, technologies, and other factors. Market participants need to pay close attention and gain insight into opportunities in order to win in the business sea.