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1-Chloro-2,4-Difluoro-5-Nitrobenzene

1-Chloro-2,4-Difluoro-5-Nitrobenzene

Hongda Chemical

Specifications

HS Code

823842

Chemical Formula C6H2ClF2NO2
Molar Mass 193.536 g/mol
Appearance Solid (usually)
Color Typically colorless to pale - yellow
Odor May have a pungent, characteristic odor
Melting Point Around 54 - 56 °C
Boiling Point Approximately 235 - 237 °C
Solubility In Water Low solubility in water
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform

As an accredited 1-Chloro-2,4-Difluoro-5-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - chloro - 2,4 - difluoro - 5 - nitrobenzene: Packed in 1 - kg bottles for chemical storage.
Storage 1 - Chloro - 2,4 - difluoro - 5 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from direct sunlight. Keep it in a tightly sealed container to prevent leakage and exposure to air and moisture. Store it separately from oxidizing agents, reducing agents, and combustibles due to potential reactivity, following all relevant safety regulations.
Shipping 1 - Chloro - 2,4 - difluoro - 5 - nitrobenzene is a chemical. It should be shipped in well - sealed, corrosion - resistant containers. Follow proper hazardous material shipping regulations, ensuring secure packaging to prevent leakage during transit.
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1-Chloro-2,4-Difluoro-5-Nitrobenzene 1-Chloro-2,4-Difluoro-5-Nitrobenzene
General Information
Historical Development
1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene is a chemical substance, and its historical development is quite instructive. In the past, chemical sages worked tirelessly on the way to explore the mysteries of matter. At the beginning, the understanding of such compounds was still shallow, and only a little bit of their properties were known.
With the passage of time, the experimental technology has become more and more exquisite, and many scholars have devoted themselves to it. After repeated trials, the method of synthesis has gradually become clear. The initial synthesis steps are complicated and the yield is not high, but everyone is not discouraged. Unremitting improvement of the process, or finding new reaction conditions, or exploring other raw materials, after countless attempts.
Up to today, the synthesis technology of 1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene has been greatly improved, the yield has been improved, and the purity has been better. It has also been widely used in various fields of chemical industry. It is an important achievement in the development of chemistry.
Product Overview
1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene, also an organic compound. Its shape is crystalline, and its color is white or off-white. It has specific rationalization, suitable melting point, and stability.
This compound is widely used in the field of organic synthesis. It can be used as an intermediate, involved in the creation of medical drugs, pesticides, etc. In the development of medicine, or as a key structural unit, to help form new drugs with curative effect; in the development of pesticides, or as a precursor of active ingredients to produce high-efficiency pesticides.
Synthesis method, through various reaction pathways. It needs to be carefully controlled by raw materials and conditions, such as catalysts, temperature, pressure, etc., to obtain higher yield and purity. When operating, safety comes first, because it may be toxic and irritating, and protection must be comprehensive.
Physical & Chemical Properties
1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene, organic compounds are also. Its physical and chemical properties are particularly important. Looking at its shape, at room temperature, it is usually a solid state, with a yellowish color, like a powder, fine and considerable.
On its melting point, it is about a specific value range. The nature of this melting point is crucial in its separation and purification processes. As for the boiling point, it also has its inherent value, reflecting the conditions required for its gasification.
Its solubility is different in common organic solvents. In some organic solvents such as ethanol and ether, it is slightly soluble, but in water, it is difficult to dissolve. This difference in solubility is related to its reaction and application in different media.
And its chemical properties are active, with chlorine, fluorine, nitro and other functional groups on the benzene ring endowing it with unique reactivity. It can participate in many organic reactions, such as nucleophilic substitution reactions, etc. It is an important raw material for organic synthesis and has great potential for application in fine chemicals and other fields.
Technical Specifications & Labeling
1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene is an important chemical substance. Its technical specifications and identification (product parameters) are extremely critical. The appearance of this substance should be [specific appearance description], the purity should be above [X]%, and the impurity content should be strictly controlled below [specific value]. Its melting point should be in the [specific melting point range], and the boiling point should be in the [specific boiling point range]. In terms of identification, the packaging should be clearly marked with the name, chemical formula, warning signs and other information. When storing and transporting, specific rules must be followed to prevent deterioration or cause danger. In this way, the rational application and safe circulation of the product in various fields can be ensured.
Preparation Method
The method of making 1-chloro-2,4-difluoro-5-nitrobenzene is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials need to be carefully selected to make them pure and suitable. Production process, the order of the first step and the control of the conditions.
At the beginning of the reaction, start with a specific substance, and combine with the raw materials according to the appropriate ratio. Temperature and pressure are both essential, and they need to be adjusted to be precise to make the reaction go forward. In the meantime, the raw materials are mixed first, and the temperature is slowly increased to promote their preliminary synthesis.
Catalytic mechanism, using a special agent to increase the speed of the reaction and the rate of the product. The dosage of this agent must be appropriate, less is less effective, and more is miscellaneous. After the reaction is completed, pure 1-chloro-2,4-difluoro-5-nitrobenzene is obtained by separation and purification. The whole process needs to be careful and abide by the procedures to obtain good products.
Chemical Reactions & Modifications
1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene is an important chemical product. Its chemical reactions are related to many chemical processes.
In past studies, the reaction conditions and yield were often the focus of attention. In the initial reaction, the standing efficiency was not ideal and there were many side reactions.
However, with the deepening of research, scholars are committed to improving it. By adjusting the ratio of reactants, such as precisely regulating the amount of halogenate and nitrogenation reagent, the reaction path can be optimized. Furthermore, the control of reaction temperature and time is also key. Moderately increasing the temperature can speed up the reaction rate, but if it is too high, it is easy to exacerbate the side reactions. After repeated tests, a suitable temperature range was found to make the reaction efficient and the side reactions controllable.
The catalyst used in the reaction was improved, and the application of the new catalyst greatly improved the selectivity and activity of the reaction. Such improvements have made the production of 1-Chloro-2,4-Difluoro-5-Nitrobenzene more efficient, stable, and the quality has also been improved.
Synonyms & Product Names
1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene, which has attracted much attention in my chemical research. Its synonymous name is also well known to researchers.
I have heard of ancient books. Although this thing is not directly described, it is a chemical wonder, although the name is different and the quality is the same. The synonymous name of this thing is a convenient way for researchers to communicate. Its trade name is also the key to identification when it is in market circulation.
Covers chemical things, the name is changeable and the quality is constant. The synonymous name of 1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene helps us to accurately identify it, which is of great benefit to experiments and production. Trade names are about trade, clear and clear, and smooth. Both are indispensable in the process of chemical research and application.
Safety & Operational Standards
1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene is an important chemical. Safety and operating practices are of paramount importance during its preparation and application.
When preparing this chemical, the experimental site must be well ventilated to prevent the accumulation of harmful gases. Experimenters should wear complete protective equipment such as protective clothing, protective gloves and goggles to avoid skin contact and eye damage. During operation, the reaction conditions such as temperature, pressure and reactant ratio should be precisely controlled according to the established procedures. If the reaction goes out of control, it is easy to cause dangerous conditions such as explosion or toxic gas leakage.
When storing 1 - Chloro - 2, 4 - Difluoro - 5 - Nitrobenzene, choose a dry, cool and ventilated place, away from fire and heat sources. It should be stored separately from oxidizing agents, reducing agents, etc. to avoid adverse reactions. At the same time, the storage container must be well sealed to prevent leakage.
During transportation, strict specifications must also be followed. Ensure that the packaging is stable and can withstand vibration and collision. Transportation vehicles should be equipped with corresponding emergency treatment equipment, in case of leakage and other accidents, they can be dealt with in time.
When using 1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene, the operator needs to be familiar with its physical and chemical properties and safety precautions in advance. After the experiment is completed, the remaining chemicals and waste should be properly disposed of and should not be discarded at will to prevent pollution to the environment.
In short, for 1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene, from preparation, storage, transportation to use, every step must strictly follow safety and operating practices, so as to ensure the safety of personnel and the environment is not endangered.
Application Area
1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene is also a chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often a key intermediate. With its unique structure, it can help synthesize a variety of specific drugs and cure various diseases.
In the field of materials science, it is also wonderfully useful. It can be integrated into new materials through specific reactions to increase the properties of materials, such as stability and weather resistance.
In addition, in the field of pesticide research and development, this substance is also indispensable. It can be used as a basic raw material to create high-efficiency and low-toxicity pesticides, protect crops from pests and diseases, and maintain a bumper harvest. Therefore, 1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene is of key value in many application fields and promotes the progress and development of related industries.
Research & Development
1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene is an important chemical product we have dedicated ourselves to researching. This substance has unique properties and has potential application value in many fields.
We have repeatedly studied its synthesis path to optimize the process and improve the yield and purity. During this time, the reaction conditions are carefully studied, and factors such as temperature, pressure, and catalyst are finely regulated to achieve the ideal reaction effect.
In the research process, we also focus on expanding its application scope. Considering its structural properties, explore possible uses in medicine, materials and other fields. With unremitting research, this chemical has been promoted from the laboratory to practical application, achieving a leap from research to development, contributing innovative results to the industry, and helping related industries to thrive.
Toxicity Research
1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene is a chemical substance, and its toxicity study is crucial. Looking at this substance, chlorine, fluorine, and nitro coexist, and the structure is special, or it is toxic.
Ancient scholars studied toxicity and re-examined its impact on living beings. When studying this substance today, think about the way it enters the body, through the mouth, through the skin or inhalation? After entering the body, how does it circulate in the viscera and meridians, and how does it damage qi, blood, yin and yang.
And look at its harm to all kinds of organisms in the environment, fish and turtles in the water, grass and trees in the mountains and forests, or suffer from it. To understand the toxicity, it is necessary to follow a rigorous method to observe its short-term and long-term effects and measure the dose of its toxicity. In this way, the depth of its toxicity can be clarified, and the basis for protection and treatment can be provided to ensure the well-being of all beings and the peace of the world.
Future Prospects
Husband 1 - Chloro - 2,4 - Difluoro - 5 - Nitrobenzene is also a chemical product. Today, I am researching it, and it is possible to develop it in the future.
This compound is used for special reasons. Or it can be used in the field of, to make special effects, to save the suffering of life. Tao is benevolent, with this material base, it may be able to create new environments and solve the plight of patients.
Or it can be used in refined chemicals to help produce high-quality materials. Work hard, This product is used to improve the efficiency and increase the effectiveness. And it is used in the system of, or it may be beneficial, The prosperity of crops, and the protection of food.
In the future, we will use the power of science and technology to further study its properties and expand its applications. It is my hope to make this agent, which can be used to help everyone, and to create well-being for the world.
Where to Buy 1-Chloro-2,4-Difluoro-5-Nitrobenzene in China?
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Frequently Asked Questions

As a leading 1-Chloro-2,4-Difluoro-5-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-chloro-2,4-difluoro-5-nitrobenzene?
1-Alkane-2,4-diene-5-carbonylbenzene, which is an important intermediate in organic synthesis. In the field of medicinal chemistry, it is often used as a key structural unit for synthesizing drug molecules. Many drugs with biological activity need to use this structure to connect other functional groups through specific chemical reactions to give drugs specific pharmacological activities, such as antibacterial, anti-inflammatory, anti-tumor, etc.
In the field of materials science, it also plays an important role. It can be used as a monomer to participate in polymerization reactions to prepare polymer materials with special properties. Because it contains conjugated double bonds and carbonyl groups, the polymer materials prepared may have unique optical and electrical properties, which have potential applications in optoelectronic materials, sensors and other fields.
In the total synthesis of natural products, it is also a key intermediate. In the synthesis path of many complex natural products, this intermediate needs to be used to construct the core skeleton of natural products through clever reaction steps, and then complete the total synthesis, which will help in-depth research on the biological activities and pharmacological effects of natural products.
Although it is not directly recorded in "Tiangong Kaiji", in the view of ancient chemical process ideas, organic synthesis also needs to follow the principle of step by step and make the best use of everything. When synthesizing this intermediate, the raw materials and reaction conditions should be carefully selected to achieve the purpose of high efficiency and green. Just like the ancient craftsmanship, we should pay attention to the selection of materials and the cooperation of processes in order to produce high-quality products. In modern organic synthesis, this concept should also be passed down to optimize the reaction process, increase yield, reduce energy consumption and pollution, and achieve sustainable development.
What are the physical properties of 1-chloro-2,4-difluoro-5-nitrobenzene?
1-Bromo-2,4-diene-5-carboxylbenzene, this substance is a kind of organic compound. Its physical properties are quite critical and have a profound impact on its performance in various chemical processes and practical applications.
In terms of appearance, 1-bromo-2,4-diene-5-carboxylbenzene is often in a crystalline solid state, which is easy to store and operate. Its color may vary slightly depending on the purity and preparation method, but it is generally almost colorless to light yellow. If it is pure, it is light in color, and if there are more impurities, it is slightly darker in color.
The melting point is of great significance for the identification and purification of this compound. After many experiments, the melting point of 1-bromo-2,4-diene-5-carboxylbenzene is within a specific range. This value is its inherent property and is indispensable in chemical analysis and quality control. By measuring the melting point, the purity of the compound can be inferred. If the measured melting point is similar to the theoretical value, it indicates that the purity is quite high; if the deviation is large, it implies that there are impurities mixed in.
In terms of solubility, 1-bromo-2,4-diene-5-carboxylbenzene exhibits different solubility properties in organic solvents. In polar organic solvents, such as ethanol, acetone, etc., it has a certain solubility. This property allows it to participate in many organic synthesis reactions. As a reactant or intermediate, it can fully contact and react with other reagents by means of the mediator of organic solvents. In water, its solubility is relatively low, which is due to the influence of hydrophobic groups in its molecular structure, resulting in weak interactions with water molecules.
In addition, the density of 1-bromo-2,4-diene-5-carboxylbenzene is also an important physical property. Its density determines the volume of space occupied under specific conditions. In scenarios involving quantitative mixing of substances and the construction of reaction systems, this parameter needs to be accurately considered to ensure that the reaction proceeds as expected.
In summary, the physical properties of 1-bromo-2,4-diene-5-carboxylbenzene, from appearance, melting point, solubility to density, are the basis for its chemical research and practical application, providing a key basis for in-depth exploration of its chemical behavior and expansion of its application field.
What are the chemical properties of 1-chloro-2,4-difluoro-5-nitrobenzene?
1-Bromo-2,4-diene-5-carboxylpyridine is an important intermediate in the field of organic synthesis. Its chemical properties are unique. It is composed of bromine atoms, conjugated diene structures, and carboxyl groups and pyridine rings.
From the perspective of bromine atoms, it has strong electronegativity, which reduces the electron cloud density at the check point where bromine atoms are located in the molecule, making it prone to nucleophilic substitution reactions. Nucleophiles can attack this bromine atom, and bromine ions leave to form new organic compounds, which are of great significance in the construction of carbon-carbon bonds or carbon-heteroatomic bonds. The
conjugated diene structure confers special electron delocalization properties to molecules. This structure gives the molecule high stability and unique optical and electronic properties. For example, it can participate in the Diels-Alder reaction, which occurs [4 + 2] cycloaddition reaction with dienolymers, and efficiently constructs a six-membered ring structure, providing an important strategy for the synthesis of complex organic compounds.
Carboxyl groups are acidic functional groups. Under appropriate conditions, acid-base neutralization can occur to form carboxylic salts. Carboxyl groups can also react with alcohols through esterification to form ester compounds, which are widely used in organic synthesis and materials science. At the same time, the carboxyl group can also participate in the condensation reaction and form amide bonds with amines, which is a key step in the synthesis of peptides and proteins.
The pyridine ring is a nitrogen-containing heterocycle, and the lone pair electrons on the nitrogen atom make the pyridine ring weakly basic and can undergo protonation reaction with acids. The pyridine ring can also combine with metal ions through coordination to form metal complexes, which play a unique role in catalytic reactions and affect the selectivity and activity of the reaction.
In summary, 1-bromo-2,4-diene-5-carboxypyridine exhibits rich and diverse chemical properties due to the synergistic effect of various functional groups, and has broad application prospects in many fields such as organic synthesis, medicinal chemistry, and materials science.
What is the production method of 1-chloro-2,4-difluoro-5-nitrobenzene?
The method of making 1-bromo-2,4-diene-5-cyanobenzene has been followed in ancient times. In the past, Fang family used various materials, in a specific order, to be refined under a delicate heat.
First take an appropriate amount of benzene and place it in a clean kettle. The kettle needs to be cast in bronze. Its shape is round and the belly is large, the mouth is small and the neck is long, so that the heat is easy to control and the material does not overflow. Then add a brominating agent. This agent is made of halogen in the sea and red copper. It is strong and good at combining with benzene. The two are fused, and the fire at the bottom of the kettle is slow to burn, and the fire at the bottom of the kettle is like the light of a firefly, burning slightly, so that the bromine gradually enters the structure of benzene, and the benzene intermediate containing bromine is synthesized.
Then, a material capable of generating dienes is introduced. This material is often collected from the essence refined from the spiritual wood in the mountains. It is warm in nature and has the ability to extend the carbon chain and produce alkenes. Here, the heat needs to be adjusted to the light of a candle, so that the material is slowly surging in the kettle, and the molecules are entangled and spliced with each other, and the chain of dienes is then formed on the benz
Then, put in the cyanide-containing crystal, which is mined from the depths of gold and stone, and has been tempered many times to remove its impurities and leave its essence, which is strong and can be firmly attached to the benzene ring. At this time, the heat needs to be fierce, just like summer thunder, which makes the material in the kettle fiercely churn, and the cyanide group can firmly adhere to the specific check point of benzene, and finally get 1-bromo-2,4-diene-5-cyanobenzene.
During this period, the control of the heat and the proportion of the material need to be absolutely good. If the heat is too strong, the material will be burnt and all previous efforts will be wasted; if the heat is insufficient, the reaction will be slow and the product will be impure. The proportion of materials is out of balance, and it is difficult to form this delicate compound. Those who use this technique need to be careful, clear-eyed and quick, and well versed in the wonders of physical properties and heat to get this good product.
What are the precautions for storing and transporting 1-chloro-2,4-difluoro-5-nitrobenzene?
1-%-2,4-diene-5-carboxylbenzene should pay attention to the following things in the storage and storage:
First, because of its certain chemical activity, the storage will be dry and good. In the tidal environment or due to hydrolysis and other reactions, its chemical properties will be changed. For example, if it is stored in a tidal cellar, the carboxyl group part may be damaged due to the action of water vapor. Tongjia can avoid the polymerization of toxic ingredients and reduce safety risks.
Second, it is necessary to avoid fire sources and high environments. This compound is mostly flammable, and it is flammable in the event of open flames, high flammability, or even explosion. Such as near high temperatures or open flames, it should not be stored.
Third, in the warehouse, the package needs to be stored. Use suitable packaging materials to ensure sealing and prevent leakage. For example, use special sealed containers to block the influence of external air, moisture and other factors. If the package does not work, it will vibrate, collide, or cause the package to break, and the material will be released, which will not only pollute the environment, but also easily lead to danger.
Fourth, it is necessary to store and store the oxidizer and the original in equal parts. Due to its chemical properties, it can be oxidized, connected to the original, or caused by strong oxidation. If it is oxidized in one place, or caused by uncontrollable oxidation reaction.
Fifth, the emergency management of fire protection and leakage in the storage and distribution phase. First, fire or leakage can be quickly destroyed. For example, if the firearm is equipped with a possible fire, there is an adsorbent material for handling leakage. In this way, the safety of 1-% 2,4-diene-5-carboxybenzene in storage and storage can be guaranteed to the greatest extent, and its chemical properties can be determined.