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1-Chloro-2,4-Difluoro-3-Nitrobenzene

1-Chloro-2,4-Difluoro-3-Nitrobenzene

Hongda Chemical

    Specifications

    HS Code

    807478

    Chemical Formula C6H2ClF2NO2
    Molar Mass 195.535 g/mol
    Appearance Solid (Typical appearance, can vary based on purity and conditions)
    Solubility In Water Low (Aromatic nitro - halide compounds generally have low water solubility)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (Aromatic compounds often dissolve in these solvents)
    Vapor Pressure Low (Typical for relatively high - molecular - weight non - volatile organic compounds)

    As an accredited 1-Chloro-2,4-Difluoro-3-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 1 - chloro - 2,4 - difluoro - 3 - nitrobenzene in a sealed, chemical - resistant bottle.
    Storage 1 - Chloro - 2,4 - difluoro - 3 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames as it is potentially flammable. Keep it in a tightly sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid dangerous reactions. Label the storage clearly for easy identification.
    Shipping 1 - Chloro - 2,4 - difluoro - 3 - nitrobenzene is a chemical that must be shipped in accordance with strict hazardous materials regulations. It should be properly packaged in corrosion - resistant containers and transported by carriers licensed for such chemicals.
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    1-Chloro-2,4-Difluoro-3-Nitrobenzene 1-Chloro-2,4-Difluoro-3-Nitrobenzene
    General Information
    Historical Development
    1 - Chloro - 2,4 - Difluoro - 3 - Nitrobenzene, also an organic compound. Its origin can be traced back to the past. In the beginning, when chemists were exploring the changes of matter, they did not hear of this thing.
    And science is gradually rising, and the sages are studying more and more deeply. At first there were wise people who paid attention to the relevant synthesis methods. Early attempts, many difficulties, to obtain pure 1 - Chloro - 2,4 - Difluoro - 3 - Nitrobenzene, it is not easy.
    However, the ancestors were unremitting, and after repeated trials, the path gradually became clear. From the initial ignorance to stable preparation. With the passage of time, the preparation process has also become more exquisite, and the output has increased day by day. This compound is gradually used in the fields of medicine and materials, contributing to the progress of science and technology and becoming an important item in today's chemical treasure house.
    Product Overview
    1 - Chloro - 2,4 - Difluoro - 3 - Nitrobenzene is also an organic compound. Its shape or crystalline state, white and pure. This compound has unique chemical properties, chlorine, fluorine, nitro and other functional groups coexist on a benzene ring.
    The chlorine atom is at a specific position in the benzene ring, giving it the activity of nucleophilic substitution reaction. The fluorine atom has high electronegativity, which affects the electron cloud distribution of the molecule, making the stability and reactivity of the compound characteristic. The presence of nitro groups not only increases the polarity of the molecule, but also serves as a key check point in many chemical reactions, which can be converted by reduction and so on.
    In the field of organic synthesis, 1-Chloro-2,4-Difluoro-3-Nitrobenzene is often an important intermediate. With it as a starting material, a variety of compounds with biological activity or special functions can be prepared through cleverly designed reaction paths, which have great application potential in the pharmaceutical, pesticide and other industries.
    Physical & Chemical Properties
    1 - Chloro - 2,4 - Difluoro - 3 - Nitrobenzene is also a chemical substance. Its physical and chemical properties are quite important to scholars. Looking at its color, it is often colorless to light yellow, just like the light yellow of morning light, pure and transparent. Its taste has a special aura, although it is difficult to describe exactly, it is placed at the end of the nose, and it can be felt unique.
    On its boiling point, under a specific pressure, it can reach a certain value, just like the boiling point of water at normal pressure is 100 degrees Celsius. This substance also has its specific boiling point temperature, which is the key sign of its gasification. As for the melting point, it is also an exact value. When the temperature drops to this point, the substance gradually condenses from liquid to solid, just like water in cold winter turns into ice.
    Its solubility varies in different solvents. In organic solvents, such as ethanol, ether, or soluble, it is like salt dissolving in water and fusing into one; in water, or poor solubility, the two are like oil and water, difficult to blend. This is the important physical and chemical properties of 1-Chloro-2,4-Difluoro-3-Nitrobenzene.
    Technical Specifications & Labeling
    1 - Chloro - 2,4 - Difluoro - 3 - Nitrobenzene is a chemical I have been researching recently. Its process specifications are related to the quality of this product. The first raw material is pure, and impurities must be controlled at an extremely small level. The synthesis method requires strict testing according to precise steps, temperature, pressure and other parameters. The reaction time is also critical. If it is too short, the reaction will not be complete, and it will be too long or cause by-products to increase.
    Product identification, when indicating its chemical name, molecular formula and molecular weight. Warning labels are indispensable because they are dangerous. Quality indicators, purity must reach high standards, and impurity content should be extremely low. In this way, the quality of 1 - Chloro - 2, 4 - Difluoro - 3 - Nitrobenzene is obtained to meet the needs of all parties.
    Preparation Method
    The method of making 1-Chloro-2,4-Difluoro-3-Nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism.
    First take an appropriate amount of fluorobenzene as the starting material and place it in the reaction kettle, and control the temperature to a suitable degree. Add a specific proportion of mixed acid, containing nitric acid and sulfuric acid, both of which are nitrifying agents. After stirring and reacting, 2,4-difluoro nitrobenzene is obtained. Pay attention to the temperature and reaction time in this step to prevent side reactions from occurring.
    Transfer 2,4-difluoro nitrobenzene to the chlorination kettle for a second time, and add an appropriate amount of chlorine gas with the help of a specific catalyst. The catalytic mechanism lies in the activation of the reactants by the catalyst to promote the reaction to proceed quickly. After chlorination reaction, the target product 1 - Chloro - 2,4 - Difluoro - 3 - Nitrobenzene was obtained. After the reaction, the pure product was obtained through separation and purification. The whole production method is closely linked, and the proportion of raw materials and reaction conditions need to be precisely controlled to obtain high-quality products.
    Chemical Reactions & Modifications
    The technique of tasting chemical industry is subtle and mysterious. In the study of compounds, it is related to the change of all things. In today's words, the chemical reaction and modification of 1-Chloro-2,4-Difluoro-3-Nitrobenzene have a lot to learn.
    The reaction of Fu and its reaction may vary depending on the reagents and conditions. Changes in temperature, pressure, and the participation of catalysts can all affect the path of its transformation. Or nucleophilic substitution, or addition elimination, each follows its own reason, but if you want to get the best effect, you must observe it carefully and proceed with caution.
    As for modification, in order to find new quality and increase its characteristics. Or adjust its structure to meet different needs; or add its group to give it a different kind of energy. Make this material in the fields of medicine and materials, have a better performance, be used by the world, and benefit people's livelihood. This is the priority of chemical research, and we should make unremitting progress to understand its mysteries and make it widely used.
    Synonyms & Product Names
    1 - Chloro - 2,4 - Difluoro - 3 - Nitrobenzene, is also a chemical thing. Its name is the same, and it is also important to the researcher. In the field of chemistry, this thing may have a name, depending on the region, culture or school.
    In ancient times, those who studied one thing and many people. Today's 1 - Chloro - 2,4 - Difluoro - 3 - Nitrobenzene, or in the land, there is a difference. Its business name is also established by the merchant due to the needs of the city and the need for publicity.
    However, it does not matter what the name is, and its original nature and unique characteristics have not been changed due to the name. The researcher investigates its essence and its nature, and should not be confused by the name. Knowing the quality and ability of this thing is the requirement of the research, not the identification of the name.
    Safety & Operational Standards
    1 - Chloro - 2,4 - Difluoro - 3 - Nitrobenzene is an important raw material for chemical synthesis. It is necessary to discuss in detail the safety and operation specifications of this substance.
    Its chemical properties are active and dangerous. For storage, it must be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Do not mix with oxidizing agents, reducing agents, alkalis, etc., to prevent violent chemical reactions and safety accidents.
    When operating, operators must strictly follow the operating procedures. Wear appropriate protective equipment, such as protective glasses, protective gloves and protective clothing, to avoid skin and eye contact. In case of accidental contact, it should be flushed with a large amount of water immediately and seek medical treatment in time.
    In the place of use, it should be equipped with perfect ventilation equipment to reduce the concentration of its steam in the air. And the corresponding fire equipment and leakage emergency treatment equipment should be provided. In the event of a leak, personnel from the leaked contaminated area should be quickly evacuated to the safe area and quarantined to strictly restrict access. Emergency personnel should wear self-contained positive pressure breathing apparatus and anti-virus clothing. Do not let leaks come into contact with combustible substances, and cut off the source of leakage as much as possible. In the case of small leaks, it can be absorbed by sand, vermiculite or other inert materials; in the case of large leaks, embankments or pits should be built for containment, and pumps should be transferred to tankers or special collectors for recycling or transportation to waste disposal sites.
    In this way, the safety of 1 - Chloro - 2,4 - Difluoro - 3 - Nitrobenzene during storage and use can be ensured, and various risks can be effectively avoided.
    Application Area
    1 - Chloro - 2,4 - Difluoro - 3 - Nitrobenzene is a special chemical substance. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help synthesize drugs with special pharmacological activities, such as targeted therapeutics for specific diseases. With its unique chemical structure, it can precisely act on diseased cells.
    In the field of materials science, this compound is also useful. It can participate in the preparation of high-performance functional materials, such as materials with special optical or electrical properties, for the manufacture of advanced electronic components, to improve the efficiency and stability of components.
    In pesticide chemistry, 1 - Chloro - 2,4 - Difluoro - 3 - Nitrobenzene can be used as an important raw material for the synthesis of new pesticides, enhancing the control effect of pesticides on pests, reducing the adverse impact on the environment, and contributing to the sustainable development of agriculture. From this point of view, it has great value and application prospects in many fields.
    Research & Development
    In recent years, I have been specializing in the field of chemistry, specializing in the product 1 - Chloro - 2,4 - Difluoro - 3 - Nitrobenzene. It is unique in nature and has great potential in organic synthesis.
    At the beginning, I explored the preparation method, but after many attempts, due to different raw materials or changes in conditions, the results were not obvious. However, I was not discouraged, and I analyzed the classics in detail, referred to the methods of various sages, and tried again and again. Finally, the purity and yield were controlled.
    As for the application, there have also been gains. In the creation of new materials, the addition of this product optimizes the properties of the material. It can increase the stability of the material, and also improve the photoelectric performance.
    Although progress has been made today, the road ahead is still far away. In the future, we want to expand its application domain and explore its ability in the fields of medicine and energy. We hope to use this material to contribute to the development of chemistry and to a greater cause.
    Toxicity Research
    The judgment of taste and smell of physical properties is related to the safety of the people. Today there is 1-Chloro-2,4-Difluoro-3-Nitrobenzene, which is essential for toxicity research.
    Detailed examination of its properties, this substance contains chlorine, fluorine, nitro and other groups. Chlorine may have certain irritation and toxicity. The characteristics of fluorine make the molecular activity change, and the presence of nitro groups often increases its reactivity and potential toxicity.
    After various experiments, its effect on organisms was observed. In microorganisms, it can disturb the order of metabolism and cause growth and reproduction to be blocked. When applied to animals, it may cause damage to organs, such as liver and kidney function. Looking at the way it enters the body, inhalation from the nose and mouth, and contact with the skin can cause harm.
    Therefore, when preparing and applying it, care should be taken. Make sure to protect it well, do not leak, and avoid poisoning, so as to ensure everyone's vitality and health, and do not ignore it.
    Future Prospects
    The future prospect concerns 1-chloro-2,4-difluoro-3-nitrobenzene. Our generation of chemical researchers, studying day and night, hope that its future will shine.
    Looking at this compound, it has a unique structure and different properties, and has unlimited potential in the fields of medicine and agrochemical. In the way of medicine, or as the cornerstone of creating new agents, it is expected to overcome difficult diseases; in the way of agrochemical, it is expected to give birth to high-efficiency green pesticides, protect crops, and increase agricultural mulberry.
    However, the road ahead is not smooth, and the art of synthesis needs to be refined to improve yield and reduce costs. In the study of safety, we must not slack off, understand its toxicity, know its harm, and protect the environment and personal safety.
    We should be enterprising, study its rationale, and make good use of its nature. With time, 1-chloro-2,4-difluoro-3-nitrobenzene will be like a bright star, illuminating the chemical industry, contributing to the well-being of mankind, and becoming a brilliant cause in the future.
    Where to Buy 1-Chloro-2,4-Difluoro-3-Nitrobenzene in China?
    As a trusted 1-Chloro-2,4-Difluoro-3-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Chloro-2,4-Difluoro-3-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-chloro-2,4-difluoro-3-nitrobenzene?
    In "Tiangong Kaiwu", (that is, kao sand, the main component of ammonium chloride) is quite widely used. It is used in the metallurgical industry and can be used as a flux. For example, when casting copper, adding kao sand can reduce the melting point of the metal, make the copper liquid flow more smoothly, and the casting is formed better. The texture of the casting is uniform, less defects, and the quality of the casting is improved.
    In alchemy and pharmaceuticals, kao sand is also used. Ancient alchemists used kao sand to participate in the preparation of many alchemy prescriptions. In pharmaceuticals, kao sand can be compatible with other medicinal materials, or play the effect of softening and dispersing knots, which can treat diseases such as scrofula, sputum nucleus, etc.; or it has the power of eroding sores and removing rot, and has an auxiliary therapeutic effect on the later stage of carbuncle sore rot.
    In leather processing, kao sand can be used for leather hair removal and softening. Soaking the leather in a solution containing kao sand can make the hair on the leather fall off more easily, and can improve the texture of the leather, making it softer and tougher, which is convenient for subsequent processing into various leather goods.
    In addition, in the ancient printing and dyeing industry, kao sand can be used as a mordant. When dyeing fabrics, adding sands helps the dye adhere better to the fabric fibers, making the dyeing more uniform and firm, the color is also more vivid and lasting, and the quality of printing and dyeing is improved. In short, sands played an important role in many industries in ancient times, providing assistance for production and life.
    What are the physical properties of 1-chloro-2,4-difluoro-3-nitrobenzene
    1-Neon-2,4-diene-3-carbonyl-indole, this substance is a chemical substance, and its physical properties are quite characteristic.
    Neon is a single-atom rare gas. Under normal temperature and pressure, neon is colorless and odorless, with extremely inactive chemical properties and few chemical reactions with other substances. Its melting point is -248.67 ° C, its boiling point is -246.08 ° C, and its density is slightly smaller than that of air. Neon glows orange-red when powered on, so it is often used in neon lights and other fields.
    As for 2,4-diene-3-carbonyl indoles, this organic compound contains functional groups such as conjugated dienes and carbonyl groups, which give it specific physical properties. Generally speaking, it is mostly solid at room temperature and has a certain melting point. In view of the existence of conjugated systems, it has characteristic absorption in the ultraviolet region and can be used as a key intermediate in the field of organic synthesis. The conjugated structure also gives it certain electronic delocalization properties, which affect its physical and chemical behavior. The existence of carbonyl groups allows it to participate in many chemical reactions involving carbonyl groups, such as nucleophilic addition. Because its molecular structure contains multiple unsaturated bonds and cyclic structures, it has certain stability and rigidity, which affects its melting point, solubility and other physical properties. In common organic solvents, there may be a certain solubility, but the solubility in water is low, which is due to the hydrophobicity of the molecule.
    Is 1-chloro-2,4-difluoro-3-nitrobenzene chemically stable?
    In terms of halogenes, their properties are originally water, but the halogenes contained in them are not pure water. Halogenes are mixed with various minerals, so their properties are different from water.
    As for dienes, they have a conjugated structure, which makes their electron clouds different from ordinary hydrocarbons. The existence of conjugated systems endows dienes with active chemistry, and they are easy to react with various reagents such as addition and polymerization, which is really unstable.
    For carboxylbenzene, the carboxyl group is connected to the benzene ring, and the carboxyl group is acidic. The benzene ring has its unique electron cloud characteristics. The two affect each other, the carboxyl group makes the electron cloud density of the ortho and para-site of the benzene ring slightly reduced, and the electrophilic substitution activity of the benzene ring is slightly reduced; the benzene ring makes the hydrogen of the hydroxyl group in the carboxyl group more easily dissociate and enhances its acidity. However, overall, carboxylbenzene is still a relatively stable compound under common conditions, and it is not easy to initiate drastic changes.
    To sum up, halogen is impure due to impurities, diene is active due to conjugated structure, and carboxylbenzene is relatively stable although it has group interaction. Therefore, among the three, carboxylbenzene has the most stable chemical properties, halogen is heterogeneous and variable, and diene is active and difficult to
    What is the production process of 1-chloro-2,4-difluoro-3-nitrobenzene?
    In the ancient times, there was a method of boiling the sea. In the land of the sea, seawater was introduced into the large kettle, and it was boiled with firewood. When the water was steamed, the crystals were dissolved. This ancient method, however, consumed a huge amount of firewood. In the land of the sea, seawater was introduced into the large kettle, and it was boiled with firewood. When the water was steamed, the crystals were dissolved. This ancient method, however, consumed a huge amount of firewood. It is also used in the fields of the sea, and seawater was introduced into the fields. With the help of sunlight exposure and force blowing, the water was naturally steamed, that is, the crystals were placed in the fields. This method of boiling the sea saves firewood, saves effort, and is more convenient.
    As for the production of 2,4-diene, it is necessary to use suitable raw materials of the compound. It is often used to control the reaction rate and other general components under the action of the catalyst of the refinement. Catalysis can make the reaction rate increase in the desired direction. If the degree is high, if the reaction rate is high or out of control, it will cause the number of side effects to increase. If the degree is low, the reaction rate will be low, and the amount of influence will be high. The same is true. The appropriate solution can promote the effective collision of the anti-reaction molecules, improve the reaction efficiency, and obtain 2,4-diene.
    The fabrication of pyridine is exquisite. Usually the phase extracted from coal tar is the starting material, and it is also obtained by synthesis. In the process of synthesis, the raw material is first made into a specific reaction to form a medium substance. In this process, the mixture is then reversed in multiple steps, such as melting, boiling water, etc. Each step needs to be controlled by the grid, and the catalysts used are also different. In the reverse process, the materials are fully mixed, reversed, divided, and lifted. Only when the mixture is removed can we obtain the best pyridine. Therefore, the fabrication methods of pyridine, 2,4-diene, and pyridine each have their own methods, and they all need to be carefully studied according to the principle of chemistry in order to obtain the best.
    Precautions for storage and transportation of 1-chloro-2,4-difluoro-3-nitrobenzene
    Mercury, 2,4-diene, and 3-carbonyl steroids should pay attention to the following matters during storage and transportation:
    Mercury is a liquid metal, which is toxic and volatile. When storing, a sealed container must be used to prevent the volatilization of mercury from escaping, causing environmental pollution and human harm. And it should be placed in a cool, dry, well-ventilated place, away from fire and heat sources, because high temperature will increase the volatilization rate of mercury. During transportation, it is also necessary to ensure that the packaging is tight and a leak-proof device is installed. In case of leakage, it can be covered with sulfur powder to form mercury sulfide and reduce toxicity.
    2,4-diene substances, many of which have unsaturated bonds and are chemically active. Storage should be in a cool and dark place, because light and high temperature are prone to reactions such as addition and polymerization, which cause deterioration. Packaging materials must have good chemical stability and do not chemically react with 2,4-diene. When transporting, prevent vibration and collision to avoid damage to the package and cause leakage.
    3-carbonyl steroids, some of which are biologically active, require strict storage conditions. It should be stored in a low temperature environment, often refrigerated or even frozen to maintain its structure and activity stability. Storage containers need to be dry due to moisture or hydrolysis and other reactions. During transportation, low temperature conditions should also be maintained, and thermal insulation equipment should be used to ensure that the temperature is suitable. At the same time, whether it is storage or transportation, it is necessary to make a good mark, indicating its characteristics, hazards and emergency treatment methods, so that relevant personnel can respond.