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1-Chloro-2,3-Difluoronitrobenzene

1-Chloro-2,3-Difluoronitrobenzene

Hongda Chemical

    Specifications

    HS Code

    559742

    Chemical Formula C6H2ClF2NO2
    Appearance colorless to light yellow liquid
    Boiling Point approx. 225 - 227 °C
    Melting Point N/A
    Density approx. 1.56 g/cm³
    Solubility In Water insoluble
    Solubility In Organic Solvents soluble in many organic solvents
    Flash Point approx. 102 °C
    Vapor Pressure low
    Stability stable under normal conditions

    As an accredited 1-Chloro-2,3-Difluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1 - chloro - 2,3 - difluoronitrobenzene: Packed in 500 - gram bottles for chemical storage.
    Storage 1 - Chloro - 2,3 - difluoronitrobenzene should be stored in a cool, dry, and well - ventilated area. Keep it away from sources of heat, ignition, and incompatible substances such as strong oxidizers and reducing agents. Store in a tightly - sealed container made of suitable materials like corrosion - resistant metal or plastic to prevent leakage and exposure to air and moisture.
    Shipping 1 - Chloro - 2,3 - difluoronitrobenzene is a chemical that requires careful shipping. It should be packaged in suitable containers, compliant with regulations. Shipment should ensure proper insulation, temperature control, and be carried by carriers experienced in handling hazardous chemicals.
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    1-Chloro-2,3-Difluoronitrobenzene 1-Chloro-2,3-Difluoronitrobenzene
    General Information
    Historical Development
    1 - Chloro - 2,3 - Difluoronitrobenzene is an important product in the chemical industry. At the beginning of its historical evolution, due to the immature chemical technology, the understanding and preparation of this product were limited. At that time, researchers explored in the dark, although it was difficult and difficult, they were determined.
    With the passage of time, chemical technologies have advanced thousands of miles. The precision of analytical methods allows for detailed insight into its structure; the optimization of synthetic processes has led to an increase in yield and purity. In the past, it took a lot of resources and time to obtain a few products, but now it can be prepared efficiently. This is due to the unremitting research of chemists of all dynasties, with wisdom and sweat, to promote 1-Chloro-2,3-Difluoronitrobenzene from ignorance to clarity, leaving a strong ink in the long history of chemical industry.
    Product Overview
    1 - Chloro - 2,3 - Difluoronitrobenzene is an important raw material for chemical synthesis. It is a colorless to light yellow liquid with a unique odor. The boiling point is about a specific range, and the density also has corresponding values. This compound is widely used in the field of organic synthesis.
    Because its molecular structure contains functional groups such as chlorine, fluorine and nitro, it is endowed with active chemical properties. In many reactions, chlorine atoms can be replaced by nucleophiles to form new carbon-heteroatom bonds; the introduction of fluorine atoms can significantly change the physical and chemical properties of compounds, improve their stability and biological activity; nitro groups can be converted into other functional groups such as amino groups through reduction and other reactions, expanding their synthesis pathways.
    With these characteristics, 1 - Chloro - 2,3 - Difluoronitrobenzene is often used as a key intermediate in the preparation of fine chemicals such as medicines, pesticides and functional materials, and occupies an important position in the chemical industry.
    Physical & Chemical Properties
    1 - Chloro - 2,3 - Difluoronitrobenzene is an organic compound, and its physical and chemical properties are very important. Looking at its physical properties, it is mostly liquid at room temperature, and its color is nearly colorless or slightly yellowish, with a special odor. This substance has a density greater than that of water and is difficult to dissolve in water, but it is easily soluble in many organic solvents, such as ethanol, ether, etc.
    When it comes to chemical properties, its chlorine atom has good activity and is easy to participate in the substitution reaction. The presence of fluorine atoms and nitro groups on the aromatic ring changes the distribution of electron clouds, affecting the reaction activity and selectivity. Nitro groups can be converted into amino groups through reduction reactions, which are widely used in the field of organic synthesis. When they react with nucleophiles, chlorine atoms are easily replaced to form new derivatives, providing various paths for organic synthesis. Understanding the physical and chemical properties of 1 - Chloro - 2, 3 - Difluoronitrobenzene is of great significance for chemical production and organic synthesis.
    Technical Specifications & Labeling
    1 - Chloro - 2,3 - Difluoronitrobenzene is an important compound in the chemical industry. Its process specifications and identification (product parameters) are extremely critical. In terms of process specifications, the reaction temperature needs to be strictly controlled, usually within a specific range, to ensure that the reaction is sufficient and the product purity is up to standard. The ratio of raw materials is also important, and each reactant is put in a precise proportion to improve the yield.
    Looking at its identification, the product parameters should be indicated in detail, such as the purity should reach a specific percentage or more, and the impurity content should be extremely low. The packaging label should be clear, indicating the name of the substance, dangerous characteristics, etc., for safe storage and transportation. In this way, the production and application of 1-Chloro-2,3-Difluoronitrobenzene can be orderly and ensure quality and safety.
    Preparation Method
    1 - Chloro - 2,3 - Difluoronitrobenzene is an important chemical raw material, and its preparation method is related to many aspects.
    The selection of raw materials should be based on suitable compounds containing chlorine, fluorine and nitro groups. If specific halogenated benzenes can be selected, they need to have precise structure and purity to ensure the accurate initiation of the reaction.
    In terms of production process, it often involves multi-step reaction. First, the halogenated benzene reacts with fluorine-containing reagents under specific conditions to promote the precise substitution of fluorine atoms. The choice of temperature, pressure and catalyst in this process is very critical. Then nitro groups are introduced, and the reaction parameters are adjusted through nitrification to ensure accurate nitro positioning.
    The reaction steps are rigorous and orderly, and each step of the reaction needs to be strictly monitored. The products of the previous reaction need to be properly handled before they can be put into the subsequent reaction to improve the purity and yield of the products.
    As for the catalytic mechanism, suitable catalysts can greatly improve the reaction rate and selectivity. For example, some metal salts or organic catalysts can effectively reduce the activation energy of the reaction and guide the reaction to proceed according to the expected path, resulting in the efficient preparation of 1-Chloro-2,3-Difluoronitrobenzene.
    Chemical Reactions & Modifications
    Taste the industry of chemical industry, in the change of things, I am exhausted. In today's discussion of 1-Chloro-2,3-Difluoronitrobenzene this product, its chemical adaptation and modification are of great importance.
    The method of the past, the reaction of this product is slow, and the yield is not high. It should be subject to various conditions, which is quite strict, resulting in a huge cost. Today is different from the past. Scholars are thinking hard and want to change its nature in order to promote its response.
    Some researchers enter it with new agents to make the reaction easier and faster. Temperature and pressure are also adjusted to make it better. In this way, the yield is improved and the quality is also good. And after modification, this material is more widely used in other industries, or in the manufacture of medicine, or in the manufacture of materials, it can develop its growth, and contribute to the progress of the industry. The wonders of chemistry can be seen in the changes in response to nature. We must study it diligently to achieve new territory.
    Synonyms & Product Names
    1 - Chloro - 2,3 - Difluoronitrobenzene, the synonym and trade name of this thing are important in chemical research. Its synonyms may be nicknamed for its chemical structure, such as according to the arrangement and bonding of atoms, and have similar expressions. As for the trade name, it varies depending on the application scenario and the manufacturer.
    In the field of chemical industry, manufacturers take unique trade names for their product characteristics or specific needs. This 1 - Chloro - 2,3 - Difluoronitrobenzene, or used in fine chemical synthesis, is a key raw material for the preparation of special materials or drugs. Its synonyms help researchers communicate accurately, and the trade name indicates the product identity in the market circulation. Knowing its synonyms and trade names is of great significance in chemical research and production practice, which can avoid confusion and promote the orderly development of the industry.
    Safety & Operational Standards
    1 - Chloro - 2,3 - Difluoronitrobenzene is an important chemical product, which is crucial for its safety and operating practices.
    During the production and preparation process, all matters must be treated with caution. First and foremost, the personnel involved in the operation of this chemical must be professionally trained and familiar with its characteristics and potential hazards. This chemical is toxic and irritating. If it is not handled carelessly, it may cause human injury. If it comes into contact with the skin, rinse it with plenty of water as soon as possible, and then go to a medical institution for treatment; if it is accidentally inhaled, it should be quickly moved to a fresh air place. If the symptoms are serious, seek medical attention.
    Furthermore, the storage environment must be strictly controlled. It should be stored in a cool and well-ventilated warehouse, away from fire and heat sources, and protected from direct sunlight. Because of its exposure to open flames, hot topics or contact with oxidants, there is a risk of combustion and explosion. It should be stored separately from oxidants and food chemicals, and should not be mixed.
    During operation, various protective measures are indispensable. Operators must wear self-priming filter gas masks (full masks), tape gas suits, and rubber gloves to prevent chemicals from coming into contact with the body. At the same time, the operation site should be equipped with suitable leakage emergency treatment equipment and suitable containment materials. In the event of a leak, personnel from the leakage contaminated area should be quickly evacuated to a safe area and quarantined to strictly restrict access. Emergency personnel must wear protective equipment, do not let leaks and combustible substances (such as wood, paper, oil, etc.) contact, small leaks can be absorbed sand, vermiculite or other inert materials, a large number of leaks need to build embankment or dig a pit to contain, with a pump transferred to the tank or special collector, recycling or transported to the waste disposal site disposal.
    In this way, to ensure the safety of 1 - Chloro - 2,3 - Difluoronitrobenzene during production, storage and use, reduce the risk of accidents, and ensure the safety of personnel and the environment from pollution.
    Application Area
    1 - Chloro - 2,3 - Difluoronitrobenzene is an important chemical substance. Its application field is wide, and it can be a key intermediate for many special drugs in the field of pharmaceutical synthesis. Through delicate chemical reactions, it can be integrated into the molecular structure of drugs to give drugs unique pharmacological activity, or enhance their targeting, and improve the accuracy and effect of treatment.
    In the field of materials science, this compound can be used to create functional materials with special properties. After specific polymerization reactions or modifications, the material can obtain properties such as excellent corrosion resistance and thermal stability, and has potential application value in high-end fields such as aerospace and electronics.
    Furthermore, in the field of agricultural chemistry, it can be used as a raw material for the synthesis of new pesticides. With its unique chemical structure, it is expected to develop high-efficiency, low-toxicity and environmentally friendly pesticide products, which will contribute to the sustainable development of agriculture.
    Research & Development
    In the field of chemical industry, new products are produced one after another. 1 - Chloro - 2,3 - Difluoronitrobenzene this product is also the object of our dedicated study. We study the matter thoroughly, explore the method of its synthesis, seek the conditions of various reactions, and hope to obtain exquisite craftsmanship.
    The road of experimentation is difficult. Or the ratio of raw materials, or the regulation of temperature, all need to be carefully grasped. If there is a slight mistake, it will be twice the result with half the effort. However, we are unremitting and repeated trials, and we will eventually get results.
    As for the expansion of its application, it is also our priority. In the field of medicine, it may be the foundation for creating new drugs; in the field of materials, it may be the end of new materials. We will persevere, hoping that this material can shine in scientific research and industry, and contribute to the development of the chemical industry to achieve unparalleled success.
    Toxicity Research
    In the chemical industry, new products emerge one after another, and among all substances, the study of toxicity is particularly important. Today there is 1-Chloro-2, 3-Difluoronitrobenzene this substance, which is related to the study of toxicity and cannot be ignored.
    Observation of 1-Chloro-2, 3-Difluoronitrobenzene, its molecular structure is unique, chlorine, fluorine, nitro and above the benzene ring. Toxicology of such structures or special characteristics. In order to explain its toxicity, it is necessary to observe its response to biological systems in a rigorous way. Or observe its damage to cells, or explore its disturbance in metabolic pathways.
    After a series of tests, it can be known that this substance may have certain toxicity. In animal experiments, observe changes in its physiological indicators, such as differences in organ function and changes in behavior. Its toxicity may stem from the activity of nitro groups, which react with biological macromolecules and cause cell damage. Or because of the nature of halogen atoms, it interferes with the biochemical process in the body. Therefore, in the production and use of this thing, strict regulations should be followed to prevent it from harming the living, to ensure the safety of the environment and the well-being of everyone.
    Future Prospects
    Husband 1 - Chloro - 2, 3 - Difluoronitrobenzene, chemical substances are also. In this world, science is advancing day by day, and the research of this substance is also in depth. Looking at its future prospects, it has extraordinary potential.
    In the field of medicine, it may be used as the basis for the creation of new drugs. With its unique chemistry, it may be able to derive special drugs to save people from disease and pain. In the field of materials, it is also expected to become the key to the development of new materials. Its structure is different, or it can give new energy to materials and be used in high-tech tools.
    Our scientific researchers should explore its endless possibilities with diligence and research. In time, we will be able to open up new frontiers, make 1 - Chloro - 2, 3 - Difluoronitrobenzene shine in the future, and add luster to human well-being.
    Where to Buy 1-Chloro-2,3-Difluoronitrobenzene in China?
    As a trusted 1-Chloro-2,3-Difluoronitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Chloro-2,3-Difluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 1-Chloro-2, 3-Difluoronitrobenzene?
    1-Chloro-2,3-difluoronitrobenzene is also an organic compound. It has a wide range of uses and is involved in all fields of chemical industry.
    It is mainly used in the synthesis of medicine. Because of its special structure, it can be used as a key intermediate to prepare a variety of specific drugs through a series of chemical reactions. For example, in the creation of antibacterial drugs, by substitution and addition with other reagents, a specific chemical structure is constructed, giving the drug antibacterial activity and helping humans resist the invasion of pathogens.
    It is also used in the field of pesticide synthesis. With this as the starting material, through clever chemical transformation, pesticides with high insecticidal and herbicidal properties can be prepared. Such pesticides can precisely act on pests, ensure the healthy growth of crops, increase food production, and make great contributions to agricultural production.
    In the field of materials science, 1-chloro-2,3-difluoronitrobenzene also has outstanding performance. It can participate in the synthesis of polymer materials, endowing the materials with excellent characteristics such as chemical corrosion resistance and high temperature resistance, making the materials suitable for harsh environments such as aerospace, electronics and electrical appliances.
    Furthermore, in the synthesis of dyes, this compound can be used as an important component. After complex chemical reactions, dyes with bright color and excellent fastness can be generated, meeting the needs of high-quality dyes in textile, printing and dyeing industries.
    In summary, 1-chloro-2,3-difluoronitrobenzene has critical uses in many fields such as medicine, pesticides, materials, and dyes, and is an indispensable and important chemical for the development of modern industry.
    1-Chloro-2, what are the physical properties of 3-Difluoronitrobenzene
    1-Chloro-2,3-difluoronitrobenzene is a kind of organic compound. It has the following physical properties:
    Looking at its shape, under room temperature and pressure, it is in a liquid state. The color of this liquid is almost colorless to light yellow, clear and with a certain transparency.
    Smell its smell, with a special aromatic smell, but this smell is not a pleasant fragrance, or has a certain stimulation to the olfactory senses.
    In terms of its density, it is heavier than water. When it is placed in a container with water, it can be seen that it sinks to the bottom of the water. This characteristic is due to its molecular structure and relative molecular mass, which makes its mass concentrated and density greater than water.
    Measure its boiling point, which is within a certain temperature range. Under specific pressure conditions, its boiling point is around [specific boiling point value]. The value of the boiling point is affected by the intermolecular forces, the Van der Waals force and the polarity between molecules, etc., which together determine the energy required for its transformation from liquid to gaseous.
    Its melting point is also a specific value, about [specific melting point value]. The melting point reflects the critical temperature at which the substance transitions from solid to liquid. At this temperature, the lattice structure begins to disintegrate, the molecular motion intensifies, and then it converts from solid to liquid.
    As for solubility, its solubility in water is very small. Because the molecular polarity of this compound is quite different from that of water, it follows the principle of "similar and soluble", so it is difficult to dissolve in water. However, it has better solubility in organic solvents, such as ethanol, ether, acetone, etc. This is because the molecular structure and polarity of organic solvents are more similar to 1-chloro-2,3-difluoronitrobenzene, and the intermolecular force can promote the two to mix with each other to form a uniform solution.
    In addition, 1-chloro-2,3-difluoronitrobenzene has a certain volatility. At room temperature, some molecules can obtain enough energy to break free from the shackles of the liquid phase and enter the gas phase. This volatility is affected by factors such as temperature, surface area, and air flow. The higher the temperature, the larger the surface area, and the faster the air flow, the faster the volatilization rate.
    What is the chemical synthesis method of 1-Chloro-2, 3-Difluoronitrobenzene
    The chemical synthesis of 1-chloro-2,3-difluoro-nitrobenzene is an important issue in the field of organic synthesis. The synthesis method often uses nitrobenzene as the starting material.
    The first step is to halogenate nitrobenzene under specific reaction conditions. The selection of suitable halogenating reagents, such as chlorine and fluorine-containing compounds, can cause chlorine and fluorine atoms to replace hydrogen atoms on the benzene ring when the catalyst exists. This process requires precise regulation of reaction temperature, time and reagent dosage. Too high or too low temperature may affect the selectivity and yield of the reaction. If the time is too short, the reaction is not complete; if the time is too long, side reactions may be triggered.
    Furthermore, after the halogenation reaction is completed, the reaction products are separated and purified. Commonly used methods include distillation, extraction, recrystallization, etc. Distillation can be separated according to the difference in boiling points of different substances; extraction can achieve the purpose of separation by the different solubility of solutes in different solvents; recrystallization can remove impurities and improve the purity of the product.
    Another synthetic route is to use other aromatic compounds as starting materials and convert them into 1-chloro-2,3-difluoronitrobenzene through a multi-step reaction. This multi-step reaction may involve many organic reaction types such as substitution, reduction, and oxidation. Each step requires careful selection of reaction conditions and reagents according to the reaction mechanism and the structural characteristics of the target product.
    Safety is also a key consideration when synthesizing 1-chloro-2,3-difluoronitrobenzene. Many reagents are toxic, corrosive or flammable and explosive, and strict safety procedures must be followed during operation, in a well-ventilated environment, and appropriate protective measures must be taken. In this way, the synthesis of 1-chloro-2,3-difluoronitrobenzene can be achieved efficiently and safely.
    1-Chloro-2, 3-Difluoronitrobenzene What are the precautions in storage and transportation?
    1-Chloro-2,3-difluoronitrobenzene is an organic compound. When storing and transporting, pay attention to the following things:
    First, the storage place must be dry and well ventilated. This compound is afraid of moisture. If the environment is humid, or chemical reactions such as hydrolysis can damage its quality. And good ventilation can avoid the accumulation of its volatile gases and avoid safety risks.
    Second, temperature control is essential. It should be stored in a cool place, away from heat sources and open flames. Because of its flammability, high temperature or open flame can easily lead to combustion or even explosion.
    Third, the storage container should be selected as the appropriate one. Corrosion-resistant materials, such as glass or specific plastic containers, should be used to prevent reactions with the container material. And the container must be tightly sealed to prevent leakage.
    Fourth, when transporting, ensure that the packaging is stable. To prevent bumps and collisions from causing damage to the container and material leakage.
    Fifth, this compound is toxic and may be harmful to the human body. Therefore, storage and transportation personnel need appropriate protective equipment, such as gloves, masks and goggles, to avoid direct contact and inhalation.
    Sixth, storage and transportation sites should be prepared with emergency treatment equipment and materials. If there is an accident such as leakage, it can be responded to in time to reduce the harm.
    What are the effects of 1-Chloro-2, 3-Difluoronitrobenzene on the environment and human health?
    1-Chloro-2,3-difluoronitrobenzene is one of the organic compounds. Its impact on the environment and human health cannot be ignored.
    In terms of the environment, if this substance is released in nature, it may persist. Its chemical structure is stable, and it is not easy to be quickly decomposed by the force of nature. Flow into water bodies, or cause changes in aquatic ecology. Aquatic organisms come into contact with it, or have toxic effects. Or damage its physiological functions, inhibit its growth and reproduction. Such as fish, shrimp, etc., or show abnormal behavior and stunted development. Enter the soil, or get tired in the soil, affect the soil quality, prevent plant roots from absorbing nutrients, and cause plant growth to be trapped.
    It is related to human health, and 1-chloro-2,3-difluoronitrobenzene is potentially harmful. It can enter the human body through breathing, skin contact or ingestion. It may irritate the respiratory tract, causing cough, asthma and other diseases. If exposed for a long time, it may damage lung function. Contact with the skin can cause redness, swelling, itching, and even burns. If eaten inadvertently, it may harm the digestive system, causing nausea, vomiting, abdominal pain, etc. And this substance may be potentially carcinogenic, long-term exposure may increase the risk of cancer. In experiments, it has been found to have mutagenic effects on experimental animals, warning of its potential threat to human genes. Therefore, the use and emission of 1-chloro-2,3-difluoronitrobenzene should be treated with caution to protect the environment and human health.