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1-Butyl-3,5-Difluorobenzene

1-Butyl-3,5-Difluorobenzene

Hongda Chemical

Specifications

HS Code

494528

Chemical Formula C10H10F2
Molecular Weight 170.183
Boiling Point Around 195 - 200 °C (estimated)
Appearance Colorless to light - colored liquid (expected for this type of compound)
Odor Aromatic odor (characteristic of benzene - based compounds)
Density Approximately 1.05 - 1.15 g/cm³ (estimated for aromatic fluorinated hydrocarbons)
Solubility In Water Low solubility, likely hydrophobic as it is an organic non - polar compound
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone, toluene
Flash Point Estimated to be in the range of 60 - 80 °C (flammability hazard range for similar compounds)

As an accredited 1-Butyl-3,5-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - butyl - 3,5 - difluorobenzene packaged in 1 - liter bottles, quantity: 50 bottles.
Storage 1 - Butyl - 3,5 - difluorobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. This helps maintain its chemical stability and reduces the risk of hazardous reactions or evaporation losses.
Shipping 1 - butyl - 3,5 - difluorobenzene is shipped in tightly - sealed, corrosion - resistant containers. Transport follows strict chemical safety regulations, ensuring proper handling to prevent spills and environmental or safety hazards during transit.
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1-Butyl-3,5-Difluorobenzene 1-Butyl-3,5-Difluorobenzene
General Information
Historical Development
1 - Butyl - 3,5 - Difluorobenzene is also an organic compound. Its origin, at the beginning of the chemical sages to study the wonderful method of organic synthesis, with the hope of creating new things. This compound, through all kinds of ingenuity and attempts, has been obtained.
At the beginning, scholars have been working hard on the construction of molecular structure. After countless adjustments to the reaction conditions, the balance of material proportions has gradually become successful. From the initial hazy conception to the grinding of repeated experiments, the synthesis method of this compound has gradually become more complete.
Its development also, with the increasing precision of chemical analysis technology, the deeper understanding of the characteristics of 1 - Butyl - 3,5 - Difluorobenzene. It is increasingly used in the field of organic synthesis, providing key raw materials for the preparation of many complex compounds. It is of great significance in the chemical industry and has become a shining pearl in the development of chemistry.
Product Overview
1-Butyl-3,5-difluorobenzene is an important raw material for organic synthesis. Its shape is colorless and transparent, with a special odor. Boiling at a specific temperature, melting also has its value, and it has good solubility in organic solvents.
This compound has a unique structure. The long chain of butyl is connected to the difluorobenzene ring, resulting in its chemical properties. Due to the high electronegativity of fluorine atoms, the polarity of the molecule is different, and it exhibits unique activity in many reactions.
The preparation method often starts with benzene and is obtained by a series of reactions such as halogenation and alkylation. In the field of organic synthesis, it can be used as an intermediate to participate in the construction of complex organic molecules. For example, in medicinal chemistry, it may help to develop new drugs; in materials science, it may improve material properties.
It is of great value in industrial production and scientific research and exploration, opening up new paths for chemical research and application.
Physical & Chemical Properties
1 - Butyl - 3,5 - Difluorobenzene is an organic compound. It has unique physical and chemical properties. Looking at its physical properties, at room temperature, it is a colorless liquid with a slightly aromatic odor. Its boiling point is suitable for a specific temperature, which makes it possible to realize the transformation of gas and liquid under certain conditions, and is quite useful in distillation and other operations.
In terms of its chemical properties, the structure of the benzene ring gives it a certain stability, but the substitution of fluorine atoms increases its activity. The existence of butyl affects its spatial resistance and electron cloud distribution. It can participate in a variety of chemical reactions, such as nucleophilic substitution reactions. Due to the electron absorption of fluorine atoms, the electron cloud density of benzene ring is reduced, and it is more vulnerable to attack by nucleophilic reagents. This compound can be used as a key intermediate in the field of organic synthesis, providing assistance for the creation of novel organic materials and drugs, which is of great value for in-depth research.
Technical Specifications & Labeling
Today there is a product called 1 - Butyl - 3,5 - Difluorobenzene. To clarify its technical specifications and identification (product parameters), you should check it carefully.
The preparation of this product requires precise methods. The selection of raw materials must be pure, and the reaction conditions must also be strictly controlled. Temperature, pressure and other parameters are all related to product quality.
Its logo should be clear, and the product parameters should be listed in detail. Appearance and purity geometry should be clear on the logo so that the viewer can see at a glance. On the packaging, there should also be clear labels to distinguish the quality of authenticity.
Strict adherence to technical specifications and accurate marking are required to obtain high-quality 1-Butyl-3,5-Difluorobenzene, which is fully capable of various applications.
Preparation Method
To prepare 1 - Butyl - 3,5 - Difluorobenzene, the raw materials and production process, reaction steps, and catalytic mechanism are the key.
In the selection of raw materials, when the appropriate reactants are carefully selected, such as fluoroaromatic hydrocarbons and halobutane, their purity and quality are related to the quality of the products. The production process should be optimized, and after many tests and investigations, in order to find an efficient method.
The reaction step is to first mix fluoroaromatic hydrocarbons and halobutane under specific conditions, add an appropriate amount of catalyst, and control the temperature, pressure and reaction time. If it is in a suitable temperature range, make it fully react and rearrange the chemical bonds.
In terms of catalytic mechanism, the selected catalyst needs to be able to effectively reduce the activation energy of the reaction and accelerate the reaction process. For example, specific metal salts or organometallic complexes are used as catalysts to precisely regulate the reaction activity and selectivity, and improve the yield and purity of the product. After all these considerations and operations, 1-Butyl-3,5-Difluorobenzene can be prepared.
Chemical Reactions & Modifications
Since modern times, chemical refinement has been achieved. The study of 1-Butyl-3,5-Difluorobenzene is becoming more and more detailed. The exploration of its chemical reaction is related to the chemical industry and is of great significance.
At the beginning, the preparation of this product, the reaction conditions are harsh, and the yield is quite low. And the resulting product is full of impurities and the purity is not ideal. The reason is that the reaction mechanism is not clear and the conditions are not properly controlled.
After careful consideration, repeated research and tests were conducted to gain insight into the reaction mechanism and improve the conditions. Adjust the temperature and pressure, and select the appropriate catalyst to make the reaction better. Today's preparation, the yield is gradually increasing, the purity is also high, and the application is more and more extensive. Therefore, the exploration and modification of chemical reactions is an important way to promote chemical progress, making outstanding contributions to the prosperity of industry and the convenience of people's livelihood.
Synonyms & Product Names
1 - Butyl - 3,5 - Difluorobenzene is also an organic compound. Its synonymous name may vary from region to region or academic school. In the industry, there may be those who are called "butyl difluorobenzene", which is a short common name, intended to highlight its main structural components.
As for the trade name, the manufacturer may also give it a unique name, in recognition of its product characteristics or to facilitate marketing activities. However, no matter how the name changes, its chemical essence is constant. This compound has attracted much attention in the field of organic synthesis, and can be used as an important intermediate to participate in many reactions, and then prepare various fine chemicals. Scholars should clarify its different names in their research to prevent miscommunication and research bias. Accurate recognition of its synonyms and trade names is of great significance in chemical research and industrial applications.
Safety & Operational Standards
1 - Butyl - 3,5 - Difluorobenzene is also a chemical product. If you want to study it well, keep it safe, and follow its work, you will have a beginning.
The whole of this thing is the first to be stored. It is advisable to place it in a place that is cool, dry, and good, to avoid fire and oxidation. Its nature or flammable, and it will appear to grow in case of fire, endangering the surroundings.
If you use it, you must not ignore it. The operator must wear suitable equipment, such as gloves, eyes, etc. To prevent the skin and eyes from connecting and being harmed by it. And when you use it, you should seek good things in the environment, and do not let it gather.
If it is unfortunate to receive this thing, quickly bring it with a large amount of water. If it enters the eye, it needs to be washed for a long time, and then ask for it. If you eat it, you must not induce vomiting, and send it for treatment as soon as possible.
Furthermore, this thing also needs to be treated according to the rules. Do not pour it with your will to prevent it from staining the environment. It must be properly placed according to the situation.
Therefore, 1-Butyl-3,5-Difluorobenzene is useful in the field of chemical research or engineering, but it is of paramount importance to keep it safe and make it safe. In this way, it is possible to avoid problems before they occur, to ensure the safety of those who study, and to clear the environment.
Application Area
1 - Butyl - 3,5 - Difluorobenzene is an organic compound with a wide range of application fields. In the field of medicinal chemistry, it may act as a key intermediate to assist in the synthesis of drug molecules with specific biological activities. Due to the unique electronic properties of fluorine atoms, it can improve the lipophilicity, metabolic stability and bioavailability of drugs. This compound may provide an opportunity for the creation of new drugs.
In the field of materials science, it may have made a name for itself in the preparation of organic optoelectronic materials. With the characteristics endowed by the molecular structure, the electronic transport properties and fluorescence properties of materials can be optimized, and then used to manufacture organic Light Emitting Diodes (OLEDs), organic solar cells and other devices to improve their performance and efficiency.
Furthermore, in the field of fine chemicals, or as a special additive, it is used in coatings, inks and other products. It can give such products unique properties such as weather resistance and chemical resistance, and expand their application scenarios.
In short, 1 - Butyl - 3,5 - Difluorobenzene has potential value in many application fields. With the deepening of research, it is expected to give birth to more innovative applications.
Research & Development
In recent years, I have focused on the research of 1 - Butyl - 3,5 - Difluorobenzene. This compound has unique properties and has great potential in the field of organic synthesis.
At the beginning, I explored the preparation method of it, and many attempts were made, but they all encountered difficulties. The choice of raw materials, the matching of proportions, and the temperature of the reaction all require fine regulation. After countless tests, a feasible method can be obtained.
Then its application is developed, and it is used in the research and development of new materials. The effect is remarkable. It can optimize the material properties, improve its stability and functionality.
Looking to the future, we want to expand its application scope and work together with colleagues to make 1-Butyl-3,5-Difluorobenzene shine in more fields and promote the progress and development of this field.
Toxicity Research
Yu Taste is dedicated to toxicological research, and recently focused on the toxicity of 1-Butyl-3,5-Difluorobenzene. Although this substance is not widely known, its potential harm should not be underestimated.
Looking at its chemical structure, the combination of fluorine and hydrocarbon groups may affect the biochemical reactions in organisms. Experiments have shown that at a specific concentration, it has a significant impact on the physiological functions of the tested organisms. At the cellular level, it interferes with the normal metabolic pathway and causes abnormal cell growth. In animal experiments, it can be seen that the behavior is different from the norm, and the physiological indicators also fluctuate.
Although the research is still shallow, it has already shown signs of its toxicity. In the future, we should deepen our research to explore its mechanism of action, clarify its degree of harm, and provide evidence for protection and treatment, so as to avoid causing serious harm to life and the environment.
Future Prospects
1 - Butyl - 3,5 - Difluorobenzene, a new product of chemical engineering. Its future prospects can be expected.
This material is unique in the field of chemical research. Or it can be used in the research of new materials. With its special properties, it can make the material have better properties, such as weather resistance, qualitative, etc. It is used in aerospace, high-end electronics, etc.
And it may become an important medium in the synthesis of chemicals, assisting chemical companies to synthesize more compounds with special functions, promoting research and providing new possibilities for solving many diseases.
We, the researchers, are committed to exploring more of its capabilities, so that this product can be widely used and benefit the world.
Where to Buy 1-Butyl-3,5-Difluorobenzene in China?
As a trusted 1-Butyl-3,5-Difluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Butyl-3,5-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Butyl-3,5-Difluorobenzene?
1-Butyl-3,5-difluorobenzene is also an organic compound. It has a wide range of uses and is used in various fields of chemical industry.
In the field of organic synthesis, it is often used as a key intermediate. Because its molecular structure contains specific functional groups and benzene rings, other functional groups can be introduced through many chemical reactions, such as substitution reactions, addition reactions, etc., to construct organic molecules with more complex structures. This is of great significance in the creation of new drugs and functional materials.
In the process of drug development, or because the structure is similar to that of bioactive molecules, compounds with specific pharmacological activities can be modified and modified. By adjusting its chemical structure, it may be possible to improve the affinity and selectivity of drugs to specific targets, thus promising to develop innovative drugs with better efficacy and less side effects.
In the field of materials science, 1-butyl-3,5-difluorobenzene can participate in the preparation of special polymer materials. Because of its fluorine atom, it can endow materials with unique properties, such as enhanced corrosion resistance, thermal stability, and low surface energy. The prepared materials may be used in aerospace, electronic devices, and other fields that require strict material properties.
In addition, in the preparation of fine chemical products, it can also be used as a raw material or additive. For example, in the production of certain high-performance coatings and lubricants, their addition may optimize the performance of the product, enhance product quality and market competitiveness.
What are the physical properties of 1-Butyl-3,5-Difluorobenzene?
1-Butyl-3,5-difluorobenzene is one of the organic compounds. Its physical properties are particularly important for its application in various scenarios.
First of all, its appearance, at room temperature and pressure, is mostly colorless and transparent liquid, clear without impurities, and has a certain fluidity. This appearance characteristic is the key to visual identification and preliminary judgment of its state in many experiments and industrial processes.
When it comes to boiling point, it is about a certain temperature range, and this value varies slightly according to factors such as environmental pressure. The characteristics of boiling point make it possible to separate and purify this compound by means of distillation and other means, according to its boiling point difference, to separate from other substances to obtain pure 1-butyl-3,5-difluorobenzene.
Melting point is also an important physical property. Knowing the melting point is of great benefit to the study of its phase transition and crystallization process. In a low temperature environment, it will gradually change from liquid to solid according to the melting point. This transformation process is quite instructive for the setting of its storage and transportation conditions.
As for density, compared with water, it has its specific value. This density characteristic can be effectively separated from other liquids according to the density difference when it involves operations such as liquid-liquid separation.
In terms of solubility, 1-butyl-3,5-difluorobenzene exhibits a certain solubility in organic solvents such as ethanol and ether. However, in water, the solubility is not good. This difference in solubility is an important consideration when selecting a suitable solvent for reaction, extraction and other operations.
In addition, its vapor pressure cannot be ignored. Vapor pressure reflects the difficulty of evaporation at a certain temperature. Those with high vapor pressure are volatile. When storing and using, it is necessary to pay attention to its volatilization characteristics to prevent loss and safety hazards.
In summary, the physical properties of 1-butyl-3,5-difluorobenzene, such as appearance, boiling point, melting point, density, solubility, and vapor pressure, are key factors in chemical research, industrial production, and many other fields, which affect its application and treatment methods.
Is 1-Butyl-3,5-Difluorobenzene chemically stable?
The stability of the chemical properties of 1-butyl-3,5-difluorobenzene depends on many factors. As far as its structure is concerned, the benzene ring has a conjugated system, which imparts certain stability. Butyl is connected to the benzene ring, and alkyl is the donator group, which can affect the electron cloud density of the benzene ring, but has a limited impact on the overall stability. The difluorine atom is also connected to the benzene ring. Fluorine has high electronegativity, and the electron-absorbing effect can reduce the electron cloud density of the benzene ring, causing its electrophilic substitution reaction activity to change.
However, the stability does not depend solely on the structure. In a high temperature environment, the thermal motion of the molecule intensifies, which may cause the vibration and distortion of the bond, or cause the decomposition or other reactions of 1-butyl-3,5-difluorobenzene, and the stability will be damaged. In case of specific chemical reagents, such as strong oxidizing agents, strong acids and bases, etc., it will also pose a challenge to its stability. Strong oxidizing agents can cause oxidation, strong acids and strong bases may cause substitution, addition and other reactions.
In addition, light may also affect its stability. When some light quantum energy is sufficient, it can stimulate the transition of electrons in the molecule, causing the molecule to be in an excited state and increase its activity, which in turn will cause photochemical reactions and affect the stability.
Overall, the stability of 1-butyl-3,5-difluorobenzene is not absolute. Under normal mild conditions, it may have a certain stability. In case of special environments and reagents, the stability needs to be determined by specific consideration of reaction conditions and interactions.
What are the synthesis methods of 1-Butyl-3,5-Difluorobenzene?
The synthesis methods of 1-butyl-3,5-difluorobenzene are different. The ancient chemical synthesis also follows the scientific method and is explored step by step.
One method can be started from 3,5-difluorobenzoic acid. First, 3,5-difluorobenzoic acid is carefully reduced with a suitable reducing agent, such as lithium aluminum hydride, to obtain 3,5-difluorobenzyl alcohol. This reduction step requires careful operation in a suitable reaction environment, such as low temperature and no water and no oxygen, to prevent accidents. After obtaining 3,5-difluorobenzyl alcohol, a suitable halogenated reagent, such as phosphorus tribromide, is reacted with to convert the hydroxyl group into a halogen atom to obtain 3,5-difluorobenzyl halogen. This halogenation step also requires controlling the reaction conditions to make the reaction proceed smoothly. Then, reagents such as butyl lithium are reacted with 3,5-difluorobenzyl halogen through a process of nucleophilic substitution, and then 1-butyl-3,5-difluorobenzene can be obtained.
Another method can start from 3,5-difluorobromobenzene. First, it is reacted with magnesium chips to prepare Grignard's reagent 3,5-difluorobenzyl magnesium bromide. The process of preparing Grignard's reagent requires a very high degree of dryness in the reaction environment. If there is a little carelessness, the reaction can be frustrated by water vapor. After preparing Grignard's reagent, it is reacted with butyl halide in the presence of a suitable catalyst. After the Grignard reaction mechanism, the target product 1-butyl-3,5-difluorobenzene can also be obtained.
Furthermore, arylation can also be used. 1-Butyl-3,5-difluorobenzene is synthesized by heating and reacting with a suitable butyl-containing aromatization reagent and 3,5-difluorobenzene in a suitable solvent under the action of a specific catalyst, such as a palladium catalyst. In this process, factors such as the choice and dosage of catalysts, reaction temperature and time all have a great influence on the success or failure of the reaction and the yield.
Although there are many methods for synthesis, they all need to be carefully operated according to scientific principles to obtain pure 1-butyl-3,5-difluorobenzene.
What is the price range of 1-Butyl-3,5-Difluorobenzene in the market?
The prices of various items in the city of Wuguan often vary with time, place and quality. As for 1-butyl-3,5-difluorobenzene, the price also follows this rule.
1-butyl-3,5-difluorobenzene sold by various merchants in the city has a wide range of prices. If you look at the ordinary quality and quantity, its price per gram may be between tens of yuan and hundreds of yuan. However, this is not accurate, but it varies for a variety of reasons.
First, the price varies depending on the place of origin. Produced far away, after long-distance transshipment, the price may increase due to freight, etc. Produced in China, if there is no freight, the price may be slightly lower.
Second, the quality of the coarse, also depends on the price. Refined, less impurities, high purity, the price must be expensive; inferior quality, containing more heterogeneous, low purity, low price.
Third, the situation of demand and supply greatly affects the price. If there are many applicants, the price will be higher if there are few suppliers; if there are few applicants, if there are many suppliers, the price will be lower.
In addition, the amount required by the buyer is also related to the price. If you buy in large quantities, you may be given a discount to promote sales, and the price will drop slightly; if you buy in small quantities, you will have no such worries, and the price will be as usual.
In summary, the market price of 1-butyl-3,5-difluorobenzene is roughly tens to hundreds of yuan per gram, but the price varies from place of origin, quality, supply and quantity, making it difficult to determine the exact number.