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1-Butoxy-3,5-Difluorobenzene

1-Butoxy-3,5-Difluorobenzene

Hongda Chemical

Specifications

HS Code

490850

Chemical Formula C10H10F2O
Molecular Weight 186.182
Appearance Liquid (Typical)
Boiling Point Data may vary, check literature
Melting Point Data may vary, check literature
Density Data may vary, check literature
Solubility Solubility characteristics would depend on solvents, data may vary
Vapor Pressure Data may vary, check literature
Flash Point Data may vary, check literature
Refractive Index Data may vary, check literature

As an accredited 1-Butoxy-3,5-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - butoxy - 3,5 - difluorobenzene in 100 - gram bottles for chemical packaging.
Storage 1 - Butoxy - 3,5 - difluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. This helps maintain its stability and reduces the risk of dangerous reactions or evaporation losses.
Shipping 1 - butoxy - 3,5 - difluorobenzene is shipped in well - sealed containers, compliant with chemical transportation regulations. Care is taken to prevent spills, with proper labeling indicating its nature, ensuring safe transit to the destination.
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1-Butoxy-3,5-Difluorobenzene 1-Butoxy-3,5-Difluorobenzene
General Information
Historical Development
1 - Butoxy - 3,5 - Difluorobenzene, an organic compound. Its initial research originated from the study of fluoroaromatic ethers by various scholars. In the past, science and technology were not as prosperous as they are today. The research of this compound depends on complicated methods, which is time-consuming and laborious, and the yield is not ideal.
However, the years pass, and the technology advances day by day. Researchers are determined to attack and improve their skills. Since the advent of new catalysts, the reaction conditions have become milder and the yield has gradually increased. What was difficult to prepare in the past can now be obtained by more convenient routes. Its application in the fields of medicine and materials has also emerged with the evolution of technology, with broad prospects. This has been the work of researchers for generations, causing 1-Butoxy-3,5-Difluorobenzene to gradually emerge from obscurity and become an indispensable existence in the field of chemistry.
Product Overview
1 - Butoxy - 3,5 - Difluorobenzene is an important organic compound. Its color is clear and transparent, and it has a special odor. In the structure of this compound, on the benzene ring, the 3rd and 5th positions are connected to a fluorine atom, and the 1st position is connected to a butoxy group.
The synthesis method often uses a specific benzene derivative as the starting material. After a multi-step reaction, the reaction conditions, such as temperature, pH, and catalyst dosage, are carefully adjusted to achieve the desired product. During the reaction process, each step needs to be precisely controlled to obtain a high-purity 1 - Butoxy - 3,5 - Difluorobenzene.
In the field of organic synthesis, this compound has a wide range of uses. It can be used as an intermediate to participate in the construction of many complex organic molecules, providing a key raw material basis for the research and development and production of fine chemicals such as medicines and pesticides. It is an indispensable substance in organic chemistry research and industrial production.
Physical & Chemical Properties
1 - Butoxy - 3,5 - Difluorobenzene is an organic compound, and its physical and chemical properties are very important. This substance is liquid at room temperature and has a certain volatility. Looking at its molecular structure, fluorine-containing atoms give it unique properties. Fluorine atoms have high electronegativity, which causes molecular polarity to change and affects their solubility. In organic solvents, or have good solubility, but in water it has poor solubility. Its boiling point and melting point are affected by intermolecular forces. Due to the presence of fluorine atoms, the intermolecular forces are enhanced, and the boiling point is relatively high. Chemically, benzene rings give it aromaticity and can undergo electrophilic substitution reactions. The presence of alkoxy groups also affects the reaction activity. Such unique physical and chemical properties determine that it may have important uses in chemical, pharmaceutical and other fields.
Technical Specifications & Labeling
Today there is a product called 1 - Butoxy - 3,5 - Difluorobenzene. The technical specifications and identification (product parameters) for its preparation are crucial to the quality and application of this substance.
To make this product, the raw materials must be selected, the ratio should be accurate, and the temperature and duration of the reaction should be strictly controlled. If the material is mixed, the order should not be disordered, otherwise the purity of the product will be affected.
In terms of identification, its physical properties, such as color, odor, melting point, etc., should be detailed so that the user can see at a glance. And the chemical properties should also be clear, such as stability, reactivity, etc., to avoid risks during use. The product parameters must be accurate, from the purity index to the impurity content, all of which are related to its use and value.
In this way, the excellent preparation of this product can make the technical specifications and labels complete, so as to meet all kinds of needs and live up to the intention of development.
Preparation Method
The method of preparing 1-Butoxy-3,5-Difluorobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. First, take 3,5-difluorophenol as the base material, use n-butanol as the solvent, and add an appropriate amount of potassium carbonate as the acid binding agent. The mixture is placed in a reactor, heated to a suitable temperature, about 80 to 90 degrees Celsius, and stirred evenly. This is a nucleophilic substitution reaction step, in which the phenolic hydroxyl group of 3,5-difluorophenol is substituted with the butoxy group in n-butanol. In order to promote the efficient reaction, an appropriate amount of potassium iodide can be added as the catalyst, which can improve the reaction rate. After the reaction is completed, the unreacted raw materials are separated by reduced pressure distillation. Pure 1-Butoxy-3,5-Difluorobenzene product was obtained by column chromatography. The preparation method pays attention to the ratio of raw materials, reaction temperature and catalytic conditions, which can ensure product quality and yield.
Chemical Reactions & Modifications
Wenfu 1 - Butoxy - 3,5 - Difluorobenzene, in the field of chemistry, the study of its reaction and modification is quite important.
To view its reaction, when considering the reaction conditions, such as temperature, pressure, catalyst and the like. The change of temperature, or speed or slow down the response; the difference of pressure, can also change the reaction path. The catalyst, on the other hand, can guide the direction of the reaction, to promote its formation and time-consuming.
As for the modification, it is designed to increase its performance. Or adjust the structure of its molecules to make it specific and suitable for various fields. To achieve this situation, we must study the principles of chemistry and make good use of various techniques. In a rigorous manner, observing its slight changes and analyzing its cause and effect, it is possible to clarify the rules of its reaction and achieve the purpose of modification. It adds to the progress of chemistry and helps this substance to rejuvenate its new light and develop its capabilities in a wider range.
Synonyms & Product Names
1 - Butoxy - 3,5 - Difluorobenzene, this substance also has its unique position in the field of my chemical research. Looking at its synonymous name, or 3,5 - difluorophenyl butyl ether, this name is based on its chemical structure, which is connected to the butoxy group and 3,5 - difluorobenzene ring. The name of its product, and it is also called the code of a specific chemical reagent, are commonly used in the industry to clarify this specific compound.
For our researchers of the generation, it is crucial to clarify the synonymous name and the name of the product. The synonymous name can help us understand its essence from different perspectives and explore its chemical properties and reaction mechanism. The name of the product is related to its experimental application and market circulation, which is convenient for procurement and communication. If you look for its raw materials for specific organic synthesis reactions and know their names, you can accurately search for them without making mistakes.
Safety & Operational Standards
1 - Butoxy - 3,5 - Difluorobenzene is an important chemical substance that needs to be clarified in detail in terms of its safety and operating practices.
When handling this substance, the first priority is to ensure that the operating environment is well ventilated. Because it may be volatile, if the ventilation is not smooth, the gas will accumulate, or cause many latent risks. The operating site should be equipped with complete ventilation equipment, such as exhaust fans, to facilitate the timely discharge of harmful gases.
Furthermore, the operator must wear appropriate protective equipment. Professional chemical protective clothing is required, which can effectively prevent the substance from direct contact with the skin and prevent skin corrosion or other damage. At the same time, protective gloves should be worn. The material of the gloves must be well tolerated to 1-Butoxy-3,5-Difluorobenzene to ensure hand safety. Eye protection is also indispensable. Goggles can prevent the substance from splashing into the eyes and avoid serious damage to the eyes.
Storage, 1-Butoxy-3,5-Difluorobenzene should be stored in a cool, dry and ventilated place. Keep away from fire and heat sources. Because the substance may be flammable, it is easy to cause combustion and explosion accidents in case of open flames and hot topics. Storage containers must be well sealed to prevent leakage. And should be stored separately from oxidants, acids and other substances to avoid chemical reactions.
If a leak unfortunately occurs, do not panic. First, the personnel in the contaminated area of the leak should be quickly evacuated to a safe area, and quarantined, and access should be strictly restricted. Emergency personnel need to wear self-contained positive pressure breathing apparatus and chemical protective clothing. Do not let leaks come into contact with combustible substances. In the case of small leaks, it can be absorbed by sand, vermiculite or other inert materials. Large leaks need to be built embankments or dug for containment, covered with foam to reduce steam disasters, and then transferred to a tanker or special collector with an explosion-proof pump, recycled or transported to a waste treatment site for disposal.
In conclusion, for the safety and operation of 1-Butoxy-3,5-Difluorobenzene, every step is essential, and operators need to strictly follow it to ensure the safety of production, experimentation and other activities.
Application Area
1 - Butoxy - 3,5 - Difluorobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help create new drugs. Because of its unique chemical structure, it can participate in many reactions and synthesize molecules with specific pharmacological activities, which is expected to overcome difficult diseases.
In the field of materials science, it also has its uses. It can be used to prepare functional materials with specific properties, such as optoelectronic materials. Its structural properties may endow materials with excellent optical and electrical properties, which can be used in display technology, optoelectronic devices, etc., to promote the progress of science and technology. In the field of fine chemicals, this compound can participate in the formulation of specialty chemicals, adding unique properties to products, meeting the needs of different industries for specialty chemicals, and is of great value in industrial production and scientific research.
Research & Development
Modern chemistry has advanced, and all kinds of new substances have been produced one after another. 1 - Butoxy - 3,5 - Difluorobenzene This compound has been studied for a long time.
The method of its synthesis has been repeatedly explored. At the beginning, following the conventional path, the yield was not as expected. Then another approach was taken to consider the variables of the ratio of each reactant, reaction temperature and duration. After many tests, a better method was finally obtained, and the yield was improved.
This compound has broad application prospects and is expected to be used as a new functional material in the field of materials science; in pharmaceutical research and development, it may be a potential active ingredient. I will continue to study and expand its properties, explore a wider range of uses, and hope to contribute to the development of chemistry and technology, so as to promote this compound from research to wider application and development.
Toxicity Research
Today there is a substance called 1 - Butoxy - 3,5 - Difluorobenzene. I am a chemical researcher, specializing in the study of the toxicity of this substance.
Look at the structure of its molecules, containing fluorine and hydrocarbon oxy groups. Fluoride is active, or involved in toxicology. Past studies have shown that fluoride-containing compounds have special toxicity, or damage the activity of biological enzymes, or disrupt the order of cell metabolism. And the position and number of fluorine in this substance are key. Its hydrocarbon oxy group also affects its fat solubility, which is related to its entry into the body of organisms.
However, to determine its true toxicity, many methods need to be taken simultaneously. When experimental organisms are tested, their physiological abnormalities are observed, organ changes are analyzed, and cytotoxic indicators are measured. It is also necessary to observe its transformation in the environment, because of its degradation products, or with other toxicity. The study of this toxicity is related to the health of organisms and environmental safety, and cannot be ignored.
Future Prospects
I have tried to study the chemical industry. In the field of 1 - Butoxy - 3,5 - Difluorobenzene, I have some thoughts in my heart, and I have also thought deeply about its future prospects.
Looking at the world today, science and technology are changing day by day, and the chemical industry is following suit and moving forward rapidly. 1 - Butoxy - 3,5 - Difluorobenzene has its use now, but the future potential is still huge. In the road of pharmaceutical synthesis, it may be able to pave the way for the development of new agents, helping doctors overcome difficult diseases and saving people's lives from pain. In the field of materials science, it may become the foundation of new materials, making materials with extraordinary properties and applied to all kinds of high-tech places.
Our researchers should be enterprising and study day and night. With unremitting efforts, we will broaden the boundaries of its application and tap its hidden potential. With time, we will be able to make 1-Butoxy-3,5-Difluorobenzene shine, and paint a magnificent picture in the future chemical world, contributing to the well-being of mankind and living up to the trust of the times.
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Frequently Asked Questions

As a leading 1-Butoxy-3,5-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Butoxy-3,5-Difluorobenzene?
1 - Butoxy - 3,5 - Difluorobenzene is one of the organic compounds. It has a wide range of uses and has important applications in various fields.
In the field of medicinal chemistry, this compound is often a key intermediate for the synthesis of new drugs. Due to its unique chemical structure, it can endow the synthesized drugs with specific pharmacological activities and pharmacokinetic properties. Through clever modification and combination, drugs with high selectivity for specific disease targets can be prepared. In the creation process of anti-cancer, anti-infection and other drugs, 1 - Butoxy - 3,5 - Difluorobenzene may play an important role in helping to develop more effective therapeutic drugs with less side effects.
It is also valuable in materials science. It can be used as a raw material for the preparation of special properties organic materials. For example, in the field of organic optoelectronic materials, materials synthesized based on this or with unique optical and electrical properties can be applied to organic Light Emitting Diode (OLED), solar cells and other devices to improve their luminous efficiency, photoelectric conversion efficiency and other key performance indicators, and promote the development of related materials and devices.
In addition, in the fine chemical industry, 1-Butoxy-3,5-Difluorobenzene can be used to synthesize fine chemicals such as high-end fragrances and coating additives. Its structural characteristics can endow fragrances with a unique aroma, or add special properties to coatings, such as improving the corrosion resistance and wear resistance of coatings, thereby enhancing the quality and added value of fine chemical products.
In short, 1-Butoxy-3,5-Difluorobenzene has shown important uses in many fields such as medicine, materials, and fine chemicals due to its unique chemical structure, which is of great significance for promoting technological progress and product upgrading in related industries.
What are the physical properties of 1-Butoxy-3,5-Difluorobenzene?
1 - Butoxy - 3,5 - Difluorobenzene is an organic compound with unique physical properties and applications in many fields of chemical industry and materials science.
This compound may be a liquid under normal conditions, with a specific boiling point and melting point. The boiling point causes it to vaporize at a specific temperature, and can be separated by distillation according to the difference in boiling point when separating and purifying. However, the specific value varies depending on purity and environmental conditions. The melting point is also an important indicator, indicating that the temperature from solid to liquid affects its storage and processing conditions.
The density of 1 - Butoxy - 3,5 - Difluorobenzene is also critical. Compared with the density of water, it can be judged to be in the water phase. If the density is greater than water, it will sink to the bottom of the water; if it is less than water, it will float to the surface of the water. This is of great significance in systems involving liquid-liquid separation or heterogeneous reactions.
Its solubility is also worthy of attention. It may have good solubility in organic solvents such as ethanol and ether. Due to the principle of similar phase solubility, the organic structure makes it favorable to dissolve with the interaction between organic solvent molecules. However, the solubility in water may be poor because of the large difference between the non-polar organic structure and the water polarity.
In addition, the volatility of 1-Butoxy-3,5-Difluorobenzene cannot be ignored. Moderate volatility makes it odor-emitting in a specific environment. And volatility is related to boiling point. Those with low boiling point are volatile or strong. This characteristic should be considered when using and storing to prevent volatile loss or cause safety problems.
In summary, the physical properties of 1-Butoxy-3,5-Difluorobenzene, such as boiling point, melting point, density, solubility, and volatility, are critical to its application and processing in chemical and materials science fields. Understanding these properties can better utilize this compound.
What are the synthesis methods of 1-Butoxy-3,5-Difluorobenzene?
1-Butoxy-3,5-Difluorobenzene is an organic compound, and its synthesis method is very important in the field of organic synthesis. According to the article of "Tiangong Kaiwu", the synthesis method is described as follows:
To obtain 1-Butoxy-3,5-Difluorobenzene, 3,5-difluorophenol and n-butyl halide can be used as starting materials. First, 3,5-difluorophenol is dissolved in an appropriate amount of organic solvents, such as N, N-dimethylformamide (DMF) or dimethyl sulfoxide (DMSO), etc. These solvents have good solubility and stability, which is conducive to the reaction.
Then, add an appropriate amount of alkali, such as potassium carbonate or sodium carbonate, to the reaction system. The function of the alkali is to neutralize the hydrogen halide generated by the reaction, causing the reaction equilibrium to shift to the right and increasing the yield. If the alkali needs to be appropriate, too much may cause side reactions, and too little will cause the reaction rate to be slow.
Then, slowly add n-butyl halide, such as n-butyl bromide or n-butyl chloride. When adding, pay attention to the reaction temperature and drip rate. If the temperature is too high, it is easy to cause side reactions; if the temperature is too low, the reaction rate is too slow. The drip rate also needs to be moderate. If it is too fast, it may lead to too high local concentration and cause side reactions; if it
During the reaction, it is necessary to continuously stir to ensure that the reactants are fully contacted and accelerate the reaction. The reaction time depends on the specific conditions, usually several hours or even tens of hours. The reaction process can be monitored by means of thin layer chromatography (TLC). When the raw material point disappears or the expected conversion rate is reached, the reaction can be regarded as the end of the reaction.
After the reaction is completed, pour the reaction solution into an appropriate amount of water and extract the product with an organic solvent. Common organic solvents include dichloromethane, ethyl acetate, etc. After extraction, the organic phases are combined and dried with a desiccant such as anhydrous sodium sulfate or magnesium sulfate to remove the moisture in the organic phase.
Finally, the product is purified by vacuum distillation or column chromatography to remove unreacted raw materials, by-products and impurities, and pure 1-Butoxy-3,5-Difluorobenzene can be obtained.
Although this synthesis method is a common route, the fine regulation of reaction conditions, the purity of raw materials and reagents, etc. have a great impact on the yield and purity of the product. Experimenters should operate with caution to obtain ideal results.
What are the precautions for 1-Butoxy-3,5-Difluorobenzene in storage and transportation?
1 - Butoxy - 3,5 - Difluorobenzene is an organic compound. When storing and transporting, the following things should be paid attention to:
First, the storage place must be dry and cool. This compound is afraid of moisture and moisture. If it is in a humid place, it may cause deterioration. A cool environment can reduce the risk of its reaction due to excessive temperature, so as to maintain its chemical stability. If it is an ancient treasure, it should also choose a dry and cool place to prevent it from spoiling.
Second, the containers for storage and transportation should be carefully selected. Containers must be made of materials that can resist the corrosion of this compound, and must be tightly sealed. If the container is improper, or the seal is not tight, the compound may leak out, which will not only damage itself, but also endanger the surrounding environment and personal safety. Just like the ancient medicine, you must use a good weapon and seal its mouth strictly to prevent the leakage of the medicine gas and damage the efficacy.
Third, keep away from fire sources and oxidants. This compound is flammable. In case of open flames or hot topics, it is easy to cause fires, and the oxidant can also react violently with it. Just like the ancients who were fireproof and must be far away from fire, this compound should also be isolated from fire sources and oxidants to be safe.
Fourth, during transportation, anti-shock and anti-collision. Bumping vibration or causing damage to the container, causing compound leakage. When properly fixed to ensure smooth transportation, it is like an ancient treasure, and it is carefully protected to prevent damage.
Fifth, the logo is clear and clear. On the storage and transportation containers, the name, characteristics, hazards and other information of the compound should be clearly marked. So that relevant personnel can see at a glance and know how to properly dispose of it, so as not to accidentally touch it and cause harm. Like ancient utensils, warning words are engraved to make people aware of its benefits.
What are the safety risks associated with 1-Butoxy-3,5-Difluorobenzene?
There are many safety risks related to 1-butoxy-3,5-difluorobenzene, which cannot be ignored. This substance is flammable. If it is near a candle, if it is not careful, it will be like dry wood in contact with fire, and it will immediately ignite a raging flame, causing the risk of fire.
Its volatile vapor and air can form an explosive mixture. If it encounters an open flame or high heat, it can cause a violent explosion, with amazing power and damage to everything around it.
Furthermore, this substance may be irritating. If it touches the skin inadvertently, it can cause skin discomfort, itching, redness, rash or ulceration in mild cases, and rash or ulceration in severe cases. If it touches the eyes, it will cause severe pain, damage the health of the eyes, and affect the vision. And inhaling its vapor is not a good thing, or causes respiratory discomfort, cough, asthma, breathing difficulties and other diseases may occur, long-term inhalation, more endangering the lungs and other respiratory organs, damage to people's vitality.
When operating, if the protection is not good, mistakenly ingesting the entrance will also harm the body, hurt the stomach and other organs, cause vomiting, abdominal pain and other diseases, and affect people's vitality. Therefore, when handling this thing, be sure to be careful, follow safety procedures, and do a good job of protection. Don't take it lightly to ensure safety.