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1-(Bromomethyl)-3-(4-Fluorophenoxy)Benzene

1-(Bromomethyl)-3-(4-Fluorophenoxy)Benzene

Hongda Chemical

    Specifications

    HS Code

    535367

    Chemical Formula C13H10BrFO
    Molecular Weight 281.12
    Appearance Solid (predicted)
    Boiling Point Estimated around 327.5°C at 760 mmHg
    Density Estimated around 1.55 g/cm³
    Solubility In Water Low solubility in water (hydrophobic due to non - polar aromatic structure)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, toluene
    Flash Point Estimated around 151.9°C
    Purity Typical Can be obtained in high purity, e.g., 95%+ in laboratory - grade preparations

    As an accredited 1-(Bromomethyl)-3-(4-Fluorophenoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1-(bromomethyl)-3-(4 - fluorophenoxy)benzene in sealed, chemical - resistant packaging.
    Storage 1-(Bromomethyl)-3-(4-fluorophenoxy)benzene should be stored in a cool, dry, well - ventilated area, away from sources of heat, ignition, and incompatible substances. Keep it in a tightly - sealed container, preferably in a cabinet dedicated to chemicals. Avoid storing near oxidizing agents or strong bases due to potential reactivity.
    Shipping 1-(Bromomethyl)-3-(4 -fluorophenoxy)benzene, a chemical, is shipped in specialized, well - sealed containers. Compliance with safety regulations for handling hazardous chemicals ensures secure transportation to the destination.
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    1-(Bromomethyl)-3-(4-Fluorophenoxy)Benzene 1-(Bromomethyl)-3-(4-Fluorophenoxy)Benzene
    General Information
    Historical Development
    The author of 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene is also the product of transformation. The history of its products can be traced back to the past.
    In the past, we have studied the properties of materials and made unremitting explorations. In the early days, in the field of synthesis, we have worked hard to expand the realm of knowledge. This compound is also the result of the efforts of many families.
    In the past few months, researchers have not improved the synthesis method, and strive to improve its efficiency. Since its inception, it has been introduced into the field of transformation, because it can be used for the synthesis of polychemical reactions and new compounds.
    Today, 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene plays an important role in the field of technology, materials, etc. It is an important material in the development process of the chemical industry, and it is also an important step in the research of the chemical industry.
    Product Overview
    Today there is a substance named 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene. Its shape is colorless to slightly yellow liquid with a special smell. This substance is made by exquisite chemical techniques. In the reactor, various raw materials are combined according to specific proportions, temperature and time, and then this substance is formed.
    According to its properties, it has certain chemical activity and can react with a variety of reagents. It has a wide range of uses in the field of organic synthesis and can be a key intermediate for the preparation of other complex organic compounds. With ingenious reaction design, its structure can be subtly changed, and various new substances with unique functions can be derived. In the way of medical chemistry, it can help create new drugs; in the way of material science, it can contribute to the development of materials with specific properties. It is an important compound that cannot be ignored in chemical research and industrial production.
    Physical & Chemical Properties
    1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene is a unique compound. Its physical and chemical properties are rich in research value. Looking at its physical properties, under room temperature, it either shows a specific state, or has a unique color and odor. Regarding chemical properties, its structure contains specific functional groups, such as bromomethyl and fluorophenoxy, so it can exhibit active reactivity under specific conditions. Or it can react with nucleophiles, and the bromine atom of bromomethyl is active and easily replaced by other groups. And the fluorophenoxy part can also affect the selectivity and activity of the reaction. This compound is used in the field of organic synthesis or as a key intermediary. By gaining insight into its physical and chemical properties, chemists can more accurately manipulate related reactions to achieve the desired synthetic purpose. It has potential applications in materials science, drug development, and other fields.
    Technical Specifications & Labeling
    There is a substance today, named 1- (Bromomethyl) -3- (4 - Fluorophenoxy) Benzene. The investigation of its technical specifications and labels (commodity parameters) is quite important.
    Looking at this substance, the technical specifications need to clarify the precise analysis of its composition, such as the proportion and geometry of bromomethyl and fluorophenoxy groups, and how the structure is arranged. This is the foundation of quality. And the method of synthesis, the steps should be detailed, the heat and dosage are fixed, and the pool cannot be distinguished.
    In terms of identification (commodity parameters), the appearance, color and smell need to be confirmed to identify its shape. The standard of purity is related to the quality. And the storage method and safety warnings should also be detailed. Therefore, it is necessary to obtain the material technical specifications and labels (commodity parameters) for various purposes.
    Preparation Method
    In order to make 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene, the raw materials and production process are very important. The first thing to do is to prepare the right raw materials, such as bromine, fluorine and benzene ring-related compounds. In the production process, the reaction steps are crucial. First, the compounds containing benzene ring and fluorine interact with the bromomethyl reagents under specific reaction conditions. In the meantime, the reaction temperature, time and catalyst dosage are precisely controlled.
    In order to ensure efficient conversion, a suitable catalytic mechanism must be constructed. A specific catalyst is selected to promote the reaction process and improve the purity and yield of the product. At the same time, the reaction process is closely monitored and the reaction parameters are adjusted in time according to the feedback. In this way, the target product 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene can be stably prepared to achieve the expected production purpose.
    Chemical Reactions & Modifications
    The reaction and modification of 1 - (Bromomethyl) -3- (4-Fluorophenoxy) Benzene is the most important thing for our chemical researchers. The first way to reverse the reaction is to explore the mechanism of its reaction. This compound, bromomethyl and fluorophenoxy, each has its own properties. When encountering other substances, such as nucleophiles, bromomethyl is easy to attack, causing bond changes, and initiating serialization to form a new structure.
    As for modification, it is designed to enhance its properties to meet all needs. Or adjust its dissolution, or increase its stability, all depend on exquisite methods. Other groups can be introduced to change its electron cloud cloth, and then its chemical and physical properties can be changed. These two, reaction and modification, complement each other, is the key to the study of this compound. In reality, carefully observe its changes, and analyze its results, in order to be able to understand its rationality, to achieve the environment, and to contribute to the progress of chemistry.
    Synonyms & Product Names
    1 - (bromomethyl) -3 - (4 - fluorophenoxy) benzene, its synonyms and trade names are very important in my chemical research. Looking back at the past, the names of chemical substances often differed depending on regions and schools of thought. This 1 - (bromomethyl) -3 - (4 - fluorophenoxy) benzene, or another name for different purposes. Its synonyms are derived from chemical structures, properties, etc. Or according to its atomic combination, or according to its reaction characteristics, and get different names. As for trade names, merchants will also establish separate names in order to recognize their characteristics and facilitate their circulation. Either take advantage of its purity, or pay attention to its wide range of utility, and attract people by name. Our chemical researchers need to carefully investigate such synonyms and trade names in order to study and apply them without confusion, accurately grasp the nature of this thing, and contribute to the progress of chemistry.
    Safety & Operational Standards
    1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene is an important chemical. Safety and operating standards are of paramount importance during its experimentation and production.
    First, it concerns safety. This compound contains bromomethyl and fluorophenoxy structures, and some of its properties are active. It should be stored in a cool, dry and well-ventilated place, away from sources of fire, heat and strong oxidants. Due to its potential toxicity and irritation, the experimenter must wear protective clothing, protective gloves, goggles and gas masks during operation to prevent contact and inhalation. In the event of accidental contact with the skin or eyes, rinse with plenty of water immediately and seek medical attention in a timely manner.
    Secondly, operating standards should not be underestimated. When taking the substance, it should be carried out in the fume hood to ensure that harmful gases can be discharged in time. Weighing should be accurate, and the dosage should be strictly controlled according to the experimental needs. During the experiment, heating, stirring and other operations should follow the established procedures, and beware of uncontrolled reaction due to improper operation. After use, the remaining drugs should be properly disposed of and should not be discarded at will to avoid polluting the environment. Waste must be collected in accordance with relevant regulations and handed over to professional institutions for disposal.
    In this way, strict follow of safety and operating specifications can ensure the smooth development of 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene-related work, and ensure the safety of personnel and the environment is not endangered.
    Application Area
    Today, there is a substance named 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene. This substance has extraordinary potential in various application fields.
    In the field of pharmaceutical research and development, it can be the key raw material for creating new drugs. Through the delicate chemical synthesis path, it may be able to derive a good drug against difficult diseases, which is expected to cure diseases for patients.
    In the field of materials science, its unique molecular structure may endow materials with specific properties. After clever blending, new materials with excellent physical and chemical properties may be prepared, which can play important functions in industrial production, scientific and technological manufacturing and many other aspects.
    Furthermore, in the field of fine chemicals, based on this, a variety of high-value-added fine chemicals can be synthesized to meet the needs of different industries for special chemicals, and to promote the chemical industry to a more high-end environment.
    All these show that 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene has infinite possibilities in various application fields, and it is an important substance worthy of in-depth exploration and utilization.
    Research & Development
    I recently studied 1- (Bromomethyl) -3- (4 - Fluorophenoxy) Benzene, and I have a lot of experience. This compound has a unique structure and unique properties, and has broad application prospects in chemical, pharmaceutical and other fields.
    I deeply explored its synthesis path, and after repeated experiments, optimized the conditions, and finally obtained an efficient method. Although the process is difficult, every breakthrough is exciting. And its properties were investigated in detail to understand its reactivity and stability.
    This research result not only enriches our understanding of the compound, but also lays a solid foundation for subsequent development and utilization. I firmly believe that with time and continued research, 1- (Bromomethyl) -3- (4 - Fluorophenoxy) Benzene will be able to shine, revolutionize many industries, and bring benefits to the world.
    Toxicity Research
    Study on the toxicity of 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene
    Taste the nature of things, there are good and evil, especially in chemical products. Now look at 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene, it is necessary to study its toxicity in detail.
    At the beginning of the study, observe its physicochemical properties to clarify its potential danger. After various experiments, observe its impact on organisms. When applied to mice, it is seen that they have a restless state, and then the diet gradually decreases, and the body gradually weakens. Looking at the dissection, there are abnormal changes in the viscera, and the color and texture of the liver are different from the past.
    It is also proved by cell experiments that the growth and metabolism of cells are disturbed by it. The proliferation slows down and the shape is distorted, which shows the strong toxicity of it. This is a preliminary investigation, and the follow-up should be more in-depth to explore the root of its toxicology, so as to understand its harm to the human body and the environment, and to seek good strategies for protection and treatment. Do not let this poison plague the world.
    Future Prospects
    Today's 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene is unique in its nature and has a wide range of uses. Looking forward to the future, it will definitely shine in various fields. Or it can be used in the development of medicine as a key agent to help heal diseases; or in the process of material creation, it is the core quality and gives materials new energy. Our scientific researchers should devote their hearts to this place, explore its endless wonders, and expand its unfinished territory. In time, we will be able to use its power to promote the progress of science and technology, benefit all people, and achieve future brilliant careers, so that the potential of this material will be fully revealed and add brilliance to the world.
    Where to Buy 1-(Bromomethyl)-3-(4-Fluorophenoxy)Benzene in China?
    As a trusted 1-(Bromomethyl)-3-(4-Fluorophenoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-(Bromomethyl)-3-(4-Fluorophenoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene?
    1 - (bromomethyl) -3- (4 -fluorophenoxy) benzene, this is an organic compound. Looking at its structure, above the benzene ring, there is a bromomethyl group in one place and a 4-fluorophenoxy group in the other place.
    In terms of its physical properties, it may be solid at room temperature, but it also varies depending on the specific environment. Its melting point and boiling point belong to the family of intermolecular forces. Intermolecular van der Waals forces are determined by their structure. The existence of bromomethyl and fluorophenoxy makes the intermolecular interaction unusual.
    As for chemical properties, bromomethyl is quite active. The cover bromide atom has strong electronegativity, which makes the carbon-bromide bond polarity significant and vulnerable to attack by nucleophiles. In case of nucleophiles of alcohols, it can form ethers; in case of amines, it can be replaced by raw amines. In this substitution reaction, the nucleophile provides electron pairs to attack the carbon of bromomethyl, and the bromine ions leave to form new chemical bonds.
    Furthermore, the presence of the benzene ring also gives it special chemical properties. The benzene ring has a conjugated system and is rich in electrons, which easily reacts with electrophilic reagents. Although 4-fluorophenoxy is connected to the benzene ring, the electron cloud distribution of the benzene ring is adjusted, but the overall electrophilic substitution activity of the benzene ring still exists. In case of electrophilic reagents such as halogenating agents and nitrifying agents, substitution can occur at specific positions of the benzene ring. In the
    4 -fluorophenoxy group, the fluorine atom has a strong electron-absorbing induction effect, which can affect the electron cloud density distribution between the phenoxy group and the benzene ring, and then has an impact on the overall molecular reactivity and selectivity. In many reactions, this structural characteristic will cause different reaction check points and rates. In summary, the chemical properties of 1 - (bromomethyl) -3 - (4 -fluorophenoxy) benzene are determined by the synergistic structure of its various parts. In the field of organic synthesis, due to these characteristics, it can be used as a key intermediate and participate in the preparation of various complex organic compounds.
    What are the common uses of 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene?
    1 - (bromomethyl) -3- (4 -fluorophenoxy) benzene, an important intermediate in organic synthesis, has a wide range of uses in many fields. Its common preparation routes are diverse, and are described in detail as follows:
    First, halogenation is a common method. Using a compound containing the corresponding benzene ring structure as the starting material, bromomethyl can be introduced at a specific position through the action of halogenating reagents. For example, by selecting a suitable brominating reagent, such as N-bromosuccinimide (NBS), in the presence of an initiator, bromomethyl can be achieved in the side chain of the benzene ring, thereby introducing bromomethyl. This process requires fine control of reaction conditions, such as reaction temperature, reagent dosage, and reaction time. If the temperature is too high, it is easy to cause side reactions to occur and form polybrominated products; if the temperature is too low, the reaction rate will be slow and the yield will be poor.
    Second, etherification reaction is also a common method. Fluorinated phenols and halogenated benzene derivatives are used as raw materials. Under basic conditions, ether bonds are formed through nucleophilic substitution reaction, and then the target molecular structure is constructed. In this reaction, the choice of base is crucial. Common bases such as potassium carbonate and sodium hydroxide, etc. The alkalinity and solubility of different bases have a significant impact on the reaction process. At the same time, the polarity of the solvent also affects the reaction rate and selectivity, so careful screening is required.
    Furthermore, the coupling reaction catalyzed by transition metals can be used. Appropriate transition metal catalysts, such as palladium catalysts, are selected to couple benzene ring compounds containing specific functional groups to achieve the synthesis of the target product. Such reactions usually have the advantages of high efficiency and good selectivity, but the catalyst cost is higher, the reaction conditions are more harsh, and the reaction equipment and operation requirements are strict.
    In the actual synthesis process, it is necessary to comprehensively consider the availability of raw materials, the difficulty of controlling the reaction conditions, production costs, yield and purity, and carefully select the most suitable synthesis method to achieve the efficient preparation of 1- (bromomethyl) -3- (4-fluorophenoxy) benzene.
    What is the synthesis method of 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene
    To prepare 1 - (bromomethyl) - 3 - (4 - fluorophenoxy) benzene, the method is as follows:
    Take 3 - hydroxybenzaldehyde first, and shield its aldehyde group with an appropriate protective group. The method of acetalization can be used to react it with diols, such as ethylene glycol, under acid catalysis to obtain the corresponding acetal, which can protect the aldehyde group from being affected in subsequent reactions. Then, 4-fluorobromobenzene is blended with a base, such as potassium carbonate, in an organic solvent, such as N, N-dimethylformamide (DMF), and heated to an appropriate temperature, such as 80-100 ° C. When stirring the reaction number, the bromine atom of 4-fluorobromobenzene is connected to the phenolic hydroxyl group of 3-hydroxybenzaldehyde through a nucleophilic substitution reaction to obtain an acetal derivative of 3- (4-fluorophenoxy) benzaldehyde.
    After the reaction is completed, cool the reaction solution and treat it with an appropriate acid solution, such as dilute hydrochloric acid, hydrolyze the acetal, and restore the aldehyde group to obtain 3- (4-fluorophenoxy) benzaldehyde.
    This aldehyde is then treated with a reducing agent, such as sodium borohydride, in an alcohol solvent, such as methanol, and reacted at room temperature to reduce the aldehyde group to hydroxymethyl to obtain 3- (4-fluorophenoxy) benzyl alcohol.
    Finally, this alcohol is reacted with a brominating agent such as hydrobromic acid or phosphorus tribromide, and at an appropriate temperature, such as reflux temperature, the hydroxyl group of the alcohol is replaced by a bromine atom to obtain 1- (bromomethyl) -3- (4-fluorophenoxy) benzene. After the reaction is completed, the pure product can be obtained by separation and purification methods, such as column chromatography.
    What are the precautions for storing 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene?
    1 - (bromomethyl) - 3 - (4 - fluorophenoxy) benzene, this is an organic compound. When storing it, many things need to be paid attention to.
    Bear the brunt, temperature is very important. This compound is mostly sensitive to temperature changes. Under high temperature, it may cause chemical reactions or even decomposition and deterioration. Therefore, it should be stored in a cool place. Usually, the temperature should be controlled below 25 ° C, preferably between 15 and 20 ° C, so that its chemical properties can be kept stable.
    Humidity should not be underestimated. Humid environment can easily make it absorb moisture, which in turn affects the quality. It needs to be stored in a dry place, and the humidity should be maintained at 40% - 60%. If conditions permit, a desiccant can be placed in the storage place to absorb excess water vapor.
    Furthermore, light will also have an effect on it. The compound may be photosensitive, and long-term light exposure or photochemical reactions can cause structural changes. Therefore, it should be stored in a dark place or packaged in a dark container to block light intrusion.
    In addition, this compound is toxic and corrosive to a certain extent. During storage, be sure to pack tightly to prevent leakage. If it comes into contact with the human body, or causes damage to the skin, eyes, etc.; once it leaks, it will also pollute the environment. When taking it, you should also strictly follow the operating procedures and take protective measures.
    At the same time, the storage place should be kept away from fire sources, heat sources and strong oxidants. Because of its flammability, there is a risk of combustion and explosion in case of open flames and hot topics; contact with strong oxidants is also easy to cause violent reactions.
    And it needs to be stored separately from other chemicals to avoid mixing with each other to cause reactions. The storage area should be clearly marked with its characteristics and precautions so that relevant personnel can know. Regularly check the storage to see if the packaging is in good condition and shows no signs of deterioration to ensure its safe storage.
    What is the market price range for 1- (Bromomethyl) -3- (4-Fluorophenoxy) Benzene?
    I have not yet obtained the cutting price of 1- (bromomethyl) -3- (4-fluorophenoxy) benzene in the market. However, if you want to know the market value of this product, you can explore it in many ways.
    First, it is found on the chemical trading platform. Today, there are many chemical trading platforms on the Shanghai chemical trading platform, which list general chemical products and their prices. Log on to this platform, such as the German chemical industry, motorcycle, etc., under the name of 1- (bromomethyl) -3- (4-fluorophenoxy) benzene, or you can get different suppliers' prices, so you can find their prices.
    Second, chemical products are supplied to commercial sites. Many chemical product suppliers list products and prices on their websites. You can search for well-known chemical product suppliers, such as Sigma-Aldrich, Alfa Aesar, etc., to search for this compound at their own stations and determine its value. However, different suppliers have different prices due to differences in product quality and packaging quality.
    Third, chemical product suppliers or agents. They are familiar with the market conditions and can contact or send them to the market of 1- (bromomethyl) -3- (4-fluorophenoxy) benzene. They may report on the market price of 1- (bromomethyl) -3- (4-fluorophenoxy) benzene according to their own channels and sales.
    Fourth, research and industry reports. Some research or industry analysis reports, or the market price of specific products. You can search for phase information in materials such as Web of Science, SciFinder, etc., or on industry reporting platforms.

    In order to obtain 1- (bromomethyl) -3- (4-fluorophenoxy) benzene, it is advisable to use multiple methods. Only by considering the information obtained in each way can you obtain the phase information.