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1-(Bromomethyl)-2-Fluorobenzene

1-(Bromomethyl)-2-Fluorobenzene

Hongda Chemical

Specifications

HS Code

712041

Chemical Formula C7H6BrF
Molecular Weight 189.024 g/mol
Appearance Colorless to light yellow liquid
Boiling Point Around 195 - 197 °C
Density Approx. 1.62 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, ethyl acetate
Flash Point Around 77 °C
Refractive Index n20/D 1.546 (typical value)

As an accredited 1-(Bromomethyl)-2-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1-(bromomethyl)-2-fluorobenzene in a sealed, corrosion - resistant bottle.
Storage 1-(Bromomethyl)-2-fluorobenzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and incompatible substances. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, bases, and moisture - sensitive compounds to prevent chemical reactions.
Shipping 1-(Bromomethyl)-2-fluorobenzene is shipped in accordance with strict chemical transport regulations. It's packaged securely in appropriate containers to prevent leakage, ensuring safe transit by road, rail, or sea.
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1-(Bromomethyl)-2-Fluorobenzene 1-(Bromomethyl)-2-Fluorobenzene
General Information
Historical Development
1- (Bromomethyl) -2-Fluorobenzene is an important compound in organic synthesis. Looking back in the past, the development of chemistry has been like a long road. At first, people's understanding of organic compounds was still shallow, and they gradually accumulated experience in the process of exploring the properties and reactions of various substances.
With the passage of time, experimental techniques have been continuously refined, and chemists have a deeper understanding of the reaction mechanism. For the synthesis of 1- (Bromomethyl) -2-Fluorobenzene, it is difficult to obtain raw materials and control the reaction conditions in the early stage. However, with the help of unremitting research, researchers have continuously optimized the synthesis path from simple experimental equipment to advanced instruments. After countless attempts and failures, Fang developed an efficient method for synthesizing this compound, enabling it to produce stably, laying the foundation for the subsequent expansion of the field of organic synthesis, and promoting the discipline of chemistry to make great strides forward.
Product Overview
1- (Bromomethyl) -2-Fluorobenzene is an important raw material for organic synthesis. It is a colorless to light yellow liquid with a special odor. This compound contains bromomethyl and fluorine atoms. Due to the active characteristics of halogen atoms, it exhibits high reactivity in many organic reactions.
In the field of organic synthesis, it is often used to construct complex organic molecular structures. Through nucleophilic substitution, bromomethyl can be replaced by various nucleophiles to achieve functional group transformation and molecular modification. The introduction of fluorine atoms can significantly change the physical, chemical properties and biological activities of molecules.
Preparation of 1- (Bromomethyl) -2-Fluorobenzene requires a specific organic synthesis path and strict control of reaction conditions to ensure product purity and yield. When storing and using, relevant safety procedures must also be followed, as it is chemically active and potentially dangerous.
Physical & Chemical Properties
1- (Bromomethyl) -2-Fluorobenzene is an organic compound. Its physical and chemical properties are unique. Looking at it, it is often colorless to light yellow liquid with a special odor. As far as the boiling point is concerned, it can reach a certain temperature under a specific pressure. This is an important physical property, which is related to its performance in separation, purification and other operations. Its chemical properties are active, and it can participate in many chemical reactions because it contains bromomethyl and fluorine atoms. Bromomethyl has good departure properties, and can undergo nucleophilic substitution reactions. It interacts with many nucleophilic reagents to form new organic compounds. The presence of fluorine atoms affects the distribution of molecular electron clouds, so that the compound exhibits unique activities in some reactions. In terms of solubility, it has certain solubility in common organic solvents such as ethanol and ether, but poor solubility in water, which is closely related to molecular polarity.
Technical Specifications & Labeling
1- (Bromomethyl) -2-Fluorobenzene is also a chemical product. Its technical quality is important. As far as the technical quality is concerned, it is necessary to clarify its degree. If it is not lower than a certain ratio, the content of the product should also be limited. Its physical properties, such as melting and boiling, are all in a specific temperature.
To the above, the name of the product should be clearly defined, that is, 1- (Bromomethyl) -2-Fluorobenzene, because it may have the characteristics of corrosion and flammability. And it is attached with the product quality, such as molecular weight, chemical formula, etc., so that the user can clarify its properties, so as to use it properly and avoid accidents.
Preparation Method
In order to prepare 1- (bromomethyl) -2 -fluorobenzene, the method of preparation should be investigated in detail.
The choice of raw materials should be based on suitable starting materials, such as fluorine-containing aromatics, supplemented by reagents that can introduce bromomethyl. The preparation process first makes the aromatics and specific reagents under suitable reaction conditions and goes through the step of substitution.
The reaction step is to control the temperature, pressure and reaction time in a specific container. Or first use fluorinated benzene as the base and bromomethylation reagents under the action of catalysts.
Catalytic mechanism, select a high-efficiency catalyst to promote the reaction speed and the rate of product extraction. Such as metal catalyst or specific organic catalyst, the reaction path is optimized, and the raw material is efficiently converted into 1- (bromomethyl) -2 -fluorobenzene. In this way, the product can be obtained by a good method.
Chemical Reactions & Modifications
Today there is a chemical thing called 1- (Bromomethyl) -2-Fluorobenzene. In the process of chemistry, reaction and modification are crucial. The reaction of this compound is related to its characteristics and application.
In the past, the reaction of this compound was investigated, focusing on common pathways, but the results were not ideal. The reaction may be difficult to control, and the yield is not perfect.
Today, chemists think about change and seek innovation. After repeated research, the influence of different conditions, such as temperature, catalysts, etc. Find a modification method, or introduce specific groups to change the electron cloud distribution and promote the reaction. In this way, the controllability of the reaction gradually increases, and the yield also increases. This is all due to the deep understanding of the chemical mechanism, which can make progress in the way of reaction and modification, and expand the application of this compound.
Synonyms & Product Names
1- (Bromomethyl) -2-Fluorobenzene is an important raw material for organic synthesis. The synonym and trade name of this thing are also called in many ways in the industry.
Guanfugu's chemical research, although not as profound as it is today, the spirit of its exploration is the same as it is today. At that time, chemists were also diligently seeking the discovery and application of new substances.
The synonym of 1- (Bromomethyl) -2-Fluorobenzene varies according to its structural characteristics and synthesis path. Or because of its combination of bromomethyl and fluorobenzene, it has different names in different books and studies. As for the product name, merchants will also take a unique name to sell it widely in order to recognize its characteristics and uses.
Although chemistry is developing rapidly today, looking back on the past, all kinds of explorations are the cornerstones. The discussion of synonyms and trade names of 1- (Bromomethyl) -2-Fluorobenzene is like a drop in the long river of chemical development, reflecting the course of past research and providing a source for today's application and innovation.
Safety & Operational Standards
1 - (bromomethyl) - 2 - fluorobenzene is also a chemical product. For this product, safe operation is of paramount importance.
All researchers of 1 - (bromomethyl) - 2 - fluorobenzene must first know its characteristics. This product has a certain chemical activity, and it is difficult to encounter substances, or there are adverse effects. Therefore, in the room, the storage is dry and well connected, and there are incompatible substances such as ignition sources and oxidation.
When operating, it is necessary to wear appropriate anti-pollution. The eyes can be used to protect the eyes from the liquid that comes out of the eyes; anti-leakage gloves can prevent them from connecting to the skin, because if the skin is connected, it may cause irritation and damage. Masks are also essential to prevent steaming, powder inhalation, and endangering health.
Furthermore, the use of this product must follow the precise operation process. Dosage is low, and it cannot be used. If there is a bad thing, it should not be poured out inadvertently, and it should be properly handled according to the safety and safety standards.
Before the product is shipped, it is even more necessary to take care of the urgent things. Such as eye washers, if they are not carefully entered into the eyes, they can be washed immediately; firearms also need to be in the warehouse to prevent one fire.
For the study of 1 - (bromomethyl) - 2 - fluorobenzene, safety is essential, and the operation must be guarded, so as to avoid danger, protect the health of researchers, and promote the benefit of research.
Application Area
1- (Bromomethyl) -2-Fluorobenzene is an important raw material for organic synthesis and has a wide range of application fields. In the field of medicinal chemistry, it can be used as a key intermediate to synthesize drug molecules with specific biological activities. Through ingenious chemical reactions, the core structure of drug molecules can be precisely constructed, which is of great significance for improving drug efficacy.
In the field of materials science, this compound can participate in the preparation of new functional materials. Its unique chemical structure endows materials with novel physical and chemical properties, such as improving the optical properties of materials, making them useful in the field of optical materials. In organic synthetic chemistry, it is often used as a reaction substrate to undergo nucleophilic substitution, coupling, and other reactions with many reagents, providing a critical path for the construction of complex organic molecules and assisting scientists in creating more structurally diverse and functionally unique organic compounds.
Research & Development
The rise of modern chemistry is based on the study of matter. Today there is 1- (Bromomethyl) -2-Fluorobenzene. We study its properties and seek the rules of its transformation, hoping to make some progress.
At the beginning, we observed its shape and quality, knew its physical properties, color and taste, and recorded them in detail. Repeated exploration of its chemical properties, so that it can be integrated with various things, and observe its changes.
After repeated experiments, we know where it is easy to materialize with others, and where it can self-stabilize. Also study the preparation method, and seek its labor-saving and efficient way.
We have worked hard to seek the wide use of this substance in various domains, or for the help of medicine, or for the advancement of materials. The road of research and pursuit is long, but we are determined and hope to achieve great success. It is the wish of our generation of researchers to make this substance used by the world and promote the prosperity of all karma.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today there is 1- (Bromomethyl) -2-Fluorobenzene, and the investigation of its toxicity is quite important.
To observe this chemical, in the context of experiments, it is necessary to observe its properties in detail. It may be harmful to the body of living beings. Try it with rats and observe the physiological changes after ingestion. If you see its fur is not shiny, its movement is slow, and its diet is waste, these are all signs of toxicity.
And it also has an impact on the environment. If the soil encounters it, it may cause changes in fertility, and plant growth will be blocked. Water flows to dye it, and aquatic things may be harmed. Therefore, as a chemical researcher, it is our responsibility to investigate the toxicity of 1- (Bromomethyl) -2-Fluorobenzene with caution, understand its harm, seek preventive measures, and protect the safety of life and the environment.
Future Prospects
In the future, our research on 1- (Bromomethyl) -2-Fluorobenzene will have a great future. It can be used in the field of technology, or it can be used to find new ways to solve many diseases. In the field of materials, it may also give birth to new materials with excellent performance to help technology. The power contained in this compound is hidden deep, waiting for us to excavate it carefully. We uphold the spirit of unremitting exploration, wisdom and energy, and hope to reveal its secrets, lead it to the future, and benefit the world, so that the results of this research will shine brightly in the river of space, achieving extraordinary achievements.
Where to Buy 1-(Bromomethyl)-2-Fluorobenzene in China?
As a trusted 1-(Bromomethyl)-2-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-(Bromomethyl)-2-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1- (Bromomethyl) -2-Fluorobenzene?
1 - (bromomethyl) -2 -fluorobenzene, this substance has a wide range of uses. In the field of organic synthesis, its position is pivotal. Due to its molecular structure, bromomethyl and fluorine atoms have unique chemical activities, which can be used as key synthetic blocks to build many complex organic compounds with specific functions.
In the field of pharmaceutical chemistry, this is used as a starting material, and through a series of delicate chemical reactions, new drug molecules can be created. The introduction of bromomethyl and fluorine atoms can significantly change the physical and chemical properties and biological activities of compounds, such as enhancing the affinity of drugs to specific targets and improving their pharmacokinetic properties, opening up a broad path for the development of new drugs.
In the field of materials science, 1- (bromomethyl) -2 -fluorobenzene also has great potential. Polymer materials with excellent properties can be prepared by polymerization with other organic or inorganic monomers. The obtained materials may have unique optical, electrical or thermal properties and show potential application value in electronic devices, optical materials, etc.
In addition, in the preparation of fine chemical products, 1- (bromomethyl) -2 -fluorobenzene is also often used as an important intermediate. With its lively chemical properties, a series of high-value-added fine chemicals can be derived, which are widely used in many industries such as fragrances, dyes, and additives to meet the needs of special chemicals in different fields.
What are the physical properties of 1- (Bromomethyl) -2-Fluorobenzene?
1 - (bromomethyl) -2 -fluorobenzene is also an organic compound. Its physical properties are quite important, and it is related to the many uses and reaction characteristics of this substance.
First of all, its appearance is often colorless to light yellow transparent liquid, which can help to identify the color and properties. It has a certain degree of volatility and will slowly dissipate in the air at room temperature and pressure.
When it comes to boiling point, it is about a specific temperature range. This value may vary slightly due to factors such as environmental pressure. The characteristics of boiling point determine the selection of conditions for separation, purification and storage.
The melting point is also one of the key physical properties. The melting point value defines the temperature limit of the substance from solid to liquid state, which is of great significance in studying its phase change and crystallization characteristics.
In terms of density, there are specific values, which are related to the stratification and distribution when mixed with other substances, and have a great impact on chemical production and experimental operations.
The solubility cannot be ignored. 1- (bromomethyl) -2 -fluorobenzene has good solubility in some organic solvents, such as common ether, dichloromethane, etc., but it has poor solubility in water. This property determines its application in reaction medium selection and product separation.
In addition, its refractive index is also a unique physical property, and the refractive index reflects the degree of light refraction of the substance, which can be used in the fields of purity detection and identification.
In summary, the physical properties of 1- (bromomethyl) -2 -fluorobenzene are rich and diverse, and the properties are interrelated. It has important application value in many fields such as organic synthesis, drug development, and materials science.
What are the chemical synthesis methods of 1- (Bromomethyl) -2-Fluorobenzene?
The chemical synthesis of 1- (bromomethyl) -2 -fluorobenzene has many paths to follow. The following are common methods:
First, use o-fluorotoluene as the starting material. First, N-bromosuccinimide (NBS) is used as the bromination reagent, azobisisobutyronitrile (AIBN) is used as the initiator, and it is heated and refluxed in an inert solvent (such as carbon tetrachloride). In this process, NBS provides bromine radicals. Under the initiation of AIBN, hydrogen atoms on o-fluorotoluene methyl are captured to form benzyl radicals, which then react with bromine to obtain 1- (bromomethyl) -2 -fluorobenzene. The reaction mechanism is clear, the conditions are easier to control, and the yield can be observed.
Second, o-fluorobenzoic acid is used as the starting material. First, it is reduced to o-fluorobenzyl alcohol, and strong reducing agents such as lithium aluminum hydride (LiAlH) can be selected to react in anhydrous ether and other solvents. After obtaining o-fluorobenzyl alcohol, it is reacted with hydrobromic acid (HBr), and the hydroxyl group is replaced by bromine atoms to obtain the target product. Although there are a few steps in this path, the raw materials are relatively easy to obtain, and the reaction selectivity of each step is acceptable.
Third, o-fluorobenzene is used with formaldehyde and hydrogen bromide as raw materials. Under the catalysis of Lewis acid (such as zinc chloride, etc.), a similar reaction of chloromethylation occurs. The benzene ring of o-fluorobromobenzene is affected by the electron cloud density, and reacts with formaldehyde and hydrogen bromide at a specific location to generate 1- (bromomethyl) -2 -fluorobenzene. The raw materials of this method are common, but the reaction conditions need to be fine-tuned to obtain better yields.
All these synthesis methods have advantages and disadvantages. In practical applications, the optimal path should be selected according to factors such as raw material availability, cost considerations, reaction conditions and subsequent separation and purification difficulty.
What to pay attention to when storing and transporting 1- (Bromomethyl) -2-Fluorobenzene
1 - (bromomethyl) -2 -fluorobenzene is an organic compound. When storing and transporting it, many matters must be paid attention to.
First words storage, this compound has a certain chemical activity and should be stored in a cool, dry and well-ventilated place. Due to high temperature, humid environment, or cause its chemical reaction, damage its quality. And should be kept away from fire and heat sources to prevent the risk of fire. This compound may be flammable, and in case of open flame or hot topic, there is a risk of combustion and explosion.
Furthermore, when storing, it should be stored separately from oxidizing agents, acids, bases and other substances. Due to its lively chemical properties, contact with their substances can easily cause violent chemical reactions and cause danger. It must also be placed out of reach of children to avoid accidental ingestion and endanger personal safety.
As for transportation, make sure that the packaging is complete and well sealed before transportation. Packaging materials need to be able to resist vibration, collision and friction to prevent container damage and material leakage. During transportation, the driving speed should not be too fast, avoid sudden braking and sharp turns, and prevent package damage due to violent shaking.
Transportation vehicles should also be equipped with corresponding varieties and quantities of fire fighting equipment and leakage emergency treatment equipment. If a leak occurs during transportation, emergency treatment can be carried out in time to reduce the harm. Transport personnel must also undergo professional training to be familiar with the properties of this compound and emergency treatment methods, so as to ensure the safety of storage and transportation.
What is the market price range for 1- (Bromomethyl) -2-Fluorobenzene?
1 - (bromomethyl) - 2 - fluorobenzene is the market, and the price is straight. The price of this compound is often affected by general factors.
First, its degree is very important. If the degree is very high, it will be difficult to synthesize and study the refined product. Because of the high quality of the product, it requires exquisite work, and the cost will rise. Or the price per gram ranges from 10 to 100 yuan.
Furthermore, the balance of supply and demand is left and right. If the market demand is strong, multiple enterprises and research are seeking each other, and the supply is limited, the supply will be reduced. On the contrary, if the demand is low, the supply will be abundant, or it will fall.
The cost of production is also a factor. The cost of raw materials and the complexity of production are all affected. If raw materials are scarce and available, or special parts and high cost are required for production, the price is also high.
The volume of sales channels also plays a role. Bulk volume is low, due to large quantities, the price may be discounted, and the price will be reduced. And through different sales platforms, the price is also low. Chemical trading platforms, or due to factors such as service, quality control, etc., are suitable for general channels.
Of course, 1- (bromomethyl) -2-fluorobenzene market is low, and the price is fixed. Roughly speaking, low-grade products cost between $10 and $10 per gram; high-grade products for special purposes cost between $10 and $100 per gram, or even more, depending on the circumstances.