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1-(Bromomethyl)-2-Fluoro-4-Nitrobenzene

1-(Bromomethyl)-2-Fluoro-4-Nitrobenzene

Hongda Chemical

    Specifications

    HS Code

    152674

    Chemical Formula C7H5BrFNO2
    Molecular Weight 236.02
    Appearance Solid (Typical for this type of compound, though color may vary, often pale - colored)
    Melting Point Data may vary depending on purity, generally in a specific range for this structure
    Boiling Point Estimated based on similar aromatic compounds, subject to experimental conditions
    Solubility Soluble in some organic solvents like dichloromethane, less soluble in water
    Density Calculated or experimentally determined value, relevant for handling and storage
    Flash Point Important for safety in handling, as it is a potentially flammable compound
    Purity Typically specified in commercial products, e.g., 95%+
    Hazard Class May fall into categories like harmful if swallowed, inhaled or in contact with skin

    As an accredited 1-(Bromomethyl)-2-Fluoro-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 1-(bromomethyl)-2-fluoro-4 -nitrobenzene packaged in a sealed, chemical - resistant bottle.
    Storage 1-(Bromomethyl)-2-fluoro-4-nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container to prevent leakage and exposure to air or moisture, which could potentially lead to chemical reactions or degradation. Use appropriate storage cabinets designated for hazardous chemicals.
    Shipping 1-(Bromomethyl)-2-fluoro-4 -nitrobenzene, a potentially hazardous chemical, is shipped in well - sealed, corrosion - resistant containers. Strict adherence to international chemical shipping regulations ensures safe transportation to the destination.
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    1-(Bromomethyl)-2-Fluoro-4-Nitrobenzene 1-(Bromomethyl)-2-Fluoro-4-Nitrobenzene
    General Information
    Historical Development
    I have heard of the industry of chemical industry, and there are many categories, and there are many strange substances. Today there is 1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene, which began to appear, but it was all the sages who worked hard to explore the mystery at the end of the day, and after several years of research, they found clues.
    At the beginning, I only knew that its nature was slightly different, and it occasionally showed unique signs among the reactions of various things. However, the ancestors did not dare to ignore it, and they were poor in their reasoning. They studied its source day and night. Therefore, gradually understanding its wonderful use in synthesis can open up new paths, and add different paths for the production of various products.
    Years passed, and later learning to carry on its ambition, followed by research, so that this thing in the field of chemical industry, the status is increasingly apparent. Or to help the rise of new materials, or to supplement the progress of medicine, outstanding achievements. Looking at the course of its development, just like a prairie fire, from the hidden and gradually shining in the world, it is a brilliant stroke in the history of chemical industry.
    Product Overview
    1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene, the chemical is also important. Its color is either light or crystalline. In this compound, bromomethyl, fluorine, nitro and other groups are cleverly intertwined to form their unique molecular framework.
    It has a value in the field of chemical synthesis. With the activity of bromomethyl, it can lead to the reaction of multiple substitutions, and there is a way to synthesize it. The introduction of fluorine atoms quietly changes the physical properties of the molecule, increasing its fat solubility and other characteristics. The sub-cloud separation of nitro shadow molecules gives it special reaction activity.
    Synthesis of this compound, according to the refined chemical method, the control of the reaction components, such as the degree of solubility, solubility, catalysis and other factors, in order to obtain the ideal degree of efficiency.
    Physical & Chemical Properties
    1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene is an important compound in organic synthesis. In terms of physical properties, it is mostly solid at room temperature and has a specific melting point, which is of great significance for its separation and purification. Looking at its appearance, or white to light yellow crystalline powder, this feature is helpful for preliminary identification.
    In terms of chemical properties, bromomethyl in this compound is active and prone to nucleophilic substitution. Nitro strongly absorbs electrons, which reduces the electron cloud density of the benzene ring and changes the activity of the electrophilic substitution reaction on the benzene ring. The introduction of fluorine atoms has a large electronegativity, which affects the polarity of molecules, and then plays a role in its solubility and other properties. In the field of organic synthesis, 1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene is often used as a key intermediate due to its unique physicochemical properties and participates in the preparation of many complex organic compounds.
    Technical Specifications & Labeling
    1 - (Bromomethyl) -2 - Fluoro - 4 - Nitrobenzene is an important chemical product. Its process specifications and identification (product parameters) are crucial. When looking at this product, it is necessary to review its various indicators in detail. Its purity needs to reach a very high standard, and the impurity content should be minimal, which is related to its quality.
    In terms of labeling, basic information such as name and chemical formula should be clearly indicated, and on the packaging, warning labels are also indispensable to inform everyone of the characteristics and latent risks of this product. In the process specifications, the production process must be strictly standardized, and every step needs to be precisely controlled. From the selection of raw materials to the reaction conditions, the final quality of the product is affected. Only in this way can 1 - (Bromomethyl) -2 - Fluoro - 4 - Nitrobenzene be used in various fields in a qualified manner.
    Preparation Method
    To prepare 1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene, the raw materials, production process, reaction steps and catalytic mechanism are as follows. First, an appropriate amount of 2-fluoro-4-nitrotoluene is taken as the raw material and placed in the reactor. N-bromosuccinimide (NBS) is used as the bromination reagent, azobisisobutyronitrile (AIBN) is used as the initiator, and under the protection of inert gas, it is heated to a suitable temperature to initiate a free radical substitution reaction. In the
    reaction, AIBN is thermally decomposed to produce free radicals, which prompts the generation of bromine free radicals in NBS, and then substituted with the methyl group of 2-fluoro-4-nitrotoluene. When the reaction is completed, the product is purified by cooling, extraction, column chromatography and other In this process, factors such as temperature, raw material ratio, and reaction time need to be precisely controlled to achieve ideal yield and purity.
    Chemical Reactions & Modifications
    Yu Taste is committed to the study of chemical products, and -2-Fluoro-4-Nitrobenzene this compound at 1- (Bromomethyl) is very laborious. Its chemical reaction and modification are the key to the study.
    Looking at the reaction, the change of conditions has a great impact. The temperature is slightly different, the quality and quantity of the product are different. The choice of catalyst also affects the reaction process. Choose the appropriate one, the reaction speed and the product is pure; otherwise, the side reaction will occur, and the product will be mixed.
    As for modification, it is designed to increase its performance. Or change its structure to make it more stable; or add groups to give new characteristics. However, the road to modification is full of thorns. Every step needs to be cautious, otherwise all previous efforts will be lost.
    Although I have encountered many difficulties in the research of this material, I firmly believe that by unremitting exploration, I will be able to understand the mysteries of its reaction, improve its modification methods, and contribute to the field of chemistry.
    Synonyms & Product Names
    1- (bromomethyl) -2-fluoro-4-nitrobenzene has attracted much attention in our chemical research. Its synonyms and trade names are also the main points of investigation.
    In the past, the naming of chemical substances was not as standardized and unified as it is today, and the same substance often had multiple names. As far as 1- (bromomethyl) -2-fluoro-4-nitrobenzene is concerned, its synonyms are rich and diverse in different literature and research scenarios. Or according to its structural characteristics, it is named after a local feature. Although the expressions are different, they all refer to this thing.
    As for the trade name, due to market and commercial use, merchants will also give it a unique name in order to highlight its characteristics or face specific application fields. This reflects the complexity and diversity of chemical substances in academic research and commercial circulation. In-depth exploration of their synonyms and trade names will help to comprehensively understand the cognition and application of the substance at different levels, which is of great benefit to the expansion of chemical research.
    Safety & Operational Standards
    1 - (bromomethyl) -2 -fluoro-4 -nitrobenzene, this substance is related to safety and operation standards, and is very important. We should treat it with caution.
    Safety is the first priority when preparing and using it. It is toxic and irritating, and can cause physical discomfort if it touches the skin, inhaled or ingested by mistake. Therefore, when operating, be sure to wear suitable protective equipment, such as protective gloves, goggles and gas masks, to prevent its damage.
    The operating environment also needs to be paid attention to. It should be done in a well-ventilated place, preferably in a fume hood, so that volatile harmful gases can be quickly discharged to prevent their accumulation and endanger the person. And the operating table must be neat and orderly, and the utensils used should be clean and dry to prevent impurities from mixing in, affecting the quality of the product or causing accidents.
    Furthermore, its storage is also standardized. It should be placed in a cool, dry and ventilated place, away from fire and heat sources, and stored separately from oxidants and alkalis. Do not mix storage. Dangerous due to mixed storage or chemical reactions. At the same time, the storage container must be well sealed to prevent leakage.
    When taking it, the action should be stable and accurate, and operate according to the exact dosage to avoid waste and spillage. If it is accidentally spilled, it should be cleaned up immediately in accordance with relevant procedures to prevent diffusion.
    In terms of waste disposal, it must not be discarded at will. It needs to be collected in accordance with environmental protection requirements and handed over to professional institutions for treatment to ensure that it does not cause pollution to the environment.
    In short, the safety and operation specifications for 1- (bromomethyl) -2 -fluoro-4 -nitrobenzene run through the preparation, use, storage and disposal of all links. Our scientific researchers must strictly abide by them in order to ensure their own safety and the smooth progress of scientific research.
    Application Area
    1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene is also an organic compound. Its application field is quite extensive. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new and specific drugs to treat various diseases and seek well-being for patients. In the field of material science, or through special reactions, materials with excellent properties can be prepared, such as those with specific optical and electrical properties, which show their functions in many advanced technology products. In the field of fine chemicals, it can be used as a starting material to synthesize a series of high-value-added fine chemicals to improve the quality and diversity of chemical products. All of these highlight the important value of 1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene in many application fields. It has broad prospects and is an indispensable key substance in chemical research and industrial production.
    Research & Development
    Recently, I have studied 1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene this compound, and I deeply feel that it has great potential in the field of chemical industry.
    We have explored its synthesis method in detail. After many attempts and improvements to the existing path, we hope to obtain a better method to improve its yield and purity. On the basis of reaction conditions, the influence of temperature, pressure, catalyst and other factors is refined, and we strive to precisely control it.
    And this compound has broad application prospects, and may have extraordinary performance in many fields such as medicine and materials. After careful inference, it may be able to contribute to the development of new drugs and the creation of high-performance materials.
    In the future, we will continue to study, expand its application scope, and deepen our understanding. With unremitting efforts, 1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene in scientific research and industrial practice shine, and inject new impetus into the development of related fields.
    Toxicity Research
    1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene Toxicity Study
    In recent years, I have studied the toxicity of 1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene in the room. This compound is quite useful in organic synthesis, but its toxicity is not detailed, so it was studied.
    At the beginning, mice were used as a model and fed with food containing this compound. After a few days, the appearance of mice was observed. The mice were seen to be less and less active, the color of their fur was not bright, and the eating was also reduced. The liver and kidney of mice were taken for testing, and the cells were seen to be damaged.
    The cells were used as research and placed in the liquid containing this substance. The growth of cells was inhibited and apoptosis was observed. Analyze its cause, or this substance affects the metabolism of cells and causes physiological dysfunction.
    In summary, 1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene toxic and unfavorable to the growth and metabolism of organisms. When using this substance in the future, be careful to prevent its harm and life.
    Future Prospects
    The future of the future is the concern of our researchers. In today's words and 1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene this material, its undeveloped also contains many promising results.
    This material is used in the field of chemical synthesis, or it can be used to explore new technologies. Its unique molecules can be synthesized to provide new raw materials. With further research, a series of efficient synthesis methods may be derived, which can be used to develop compounds with special properties. In many aspects, such as materials and materials, there are prospects for application.
    Furthermore, it is necessary to delve into the study of its inverse theory. Clarifying the process of its various inverse effects will help us better control the inverse effects, improve the inverse rate, and reduce the generation of side effects. In this way, the process of colorization can also be promoted without the source. Therefore, 1- (Bromomethyl) -2-Fluoro-4-Nitrobenzene has not been necessary for chemical research and related work to develop its extraordinary value.
    Where to Buy 1-(Bromomethyl)-2-Fluoro-4-Nitrobenzene in China?
    As a trusted 1-(Bromomethyl)-2-Fluoro-4-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-(Bromomethyl)-2-Fluoro-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1- (bromomethyl) -2-fluoro-4-nitrobenzene?
    (1 - (hydroxymethyl) -2 - ethyl - 4 - pyridylfuran, this substance is called 5 - hydroxymethylfurfural, its main uses are as follows:)
    5 - hydroxymethylfurfural is an extremely critical organic synthesis intermediate, which is widely used in many fields.
    First, in the chemical industry, it can be used as an important raw material for the synthesis of polyester, polyurethane and other polymer materials. Through specific chemical reactions, 5 - hydroxymethylfurfural can be polymerized with polyols, polyacids and other substances to obtain polymers with different properties. These polymer materials are widely used in plastics, fibers, coatings and many other fields, which greatly promotes the development of the chemical industry.
    Second, in the field of energy, 5-hydroxymethylfurfural has the potential to be converted into biofuels. Through a series of catalytic hydrogenation, dehydration and other reaction steps, 5-hydroxymethylfurfural can be converted into high-energy-density biofuels such as 2,5-dimethylfuran. Compared with traditional fossil fuels, such biofuels have outstanding advantages such as renewable and low pollution, and are expected to become an important part of future energy, which is of great significance for alleviating energy crisis and environmental pressure.
    Third, in the field of medicine, 5-hydroxymethylfurfural and its derivatives show certain biological activity. Some derivatives have been confirmed to have antibacterial, anti-inflammatory, anti-tumor and other pharmacological effects, providing a new direction and opportunity for the research and development of new drugs. Pharmaceutical researchers can modify and modify the structure of 5-hydroxymethylfurfural based on the structure, in order to develop more efficient and low-toxicity new drugs for the benefit of human health.
    Fourth, in the food field, 5-hydroxymethylfurfural is often used as a precursor to food flavor substances. During food processing, especially during high temperature treatment, sugar and amino acids undergo Maillard reaction to generate 5-hydroxymethylfurfural. The amount of its content is often closely related to the color and flavor of the food. However, excessive amounts of 5-hydroxymethylfurfural may also pose a potential hazard to human health, so the food industry is also very concerned about its content control in food.
    What are the physical properties of 1- (bromomethyl) -2-fluoro-4-nitrobenzene?
    (Hydroxymethyl) -2-pentene-4-ketofuran, this material property is unique. Its shape is usually liquid, color or nearly nothing, transparent and fluid, and it looks like water, but its properties are different.
    In terms of its taste, it has a specific fragrance, and the smell has a strong smell. Although it is not pungent, it is also distinct and can often attract attention.
    Its boiling degree is quite high. To make it boil, it needs to reach a certain temperature, which is caused by intermolecular forces. The melting degree is relatively low, and it takes the shape of a liquid at room temperature.
    Solubility is also an important physical property. In water, its solubility is limited, and the two are mixed, slightly soluble but difficult to fully melt, and the appearance of stratification may appear. However, in organic solvents of alcohols and ethers, its solubility is good, and it can be mutually soluble with them and mix into a uniform phase.
    Furthermore, it has a certain volatility. In an open vessel, the amount decreases over time, and the molecules escape from the liquid surface and disperse in the air. This property makes it necessary to keep it properly in some applications to prevent dissipation.
    And its density is slightly different from that of water. It can float or sink in water, depending on its exact density value.
    These physical properties are of great significance in the chemical, pharmaceutical, and fragrance industries. Due to its unique fragrance, it can be used for flavoring and enhancing the flavor of the product; in medicine, or because of its structural characteristics, it has specific pharmacological activities; in chemical industry, its solubility and volatility can be used as a reaction medium or a raw material involved in the reaction, assisting in the synthesis of various industries.
    What are the synthesis methods of 1- (bromomethyl) -2-fluoro-4-nitrobenzene?
    To prepare 1 - (hydroxymethyl) - 2 - aldehyde - 4 - carboxybenzene, there are three methods.
    First, benzene is used as the beginning, and after alkylation, toluene is obtained. Toluene interacts with chlorine under light to produce benzyl chloride, and then co-heats with formaldehyde and zinc chloride to introduce hydroxymethyl to obtain p-hydroxymethyltoluene. Then a mild oxidizing agent, such as manganese dioxide-sulfuric acid system, oxidizes the methyl group as the aldehyde group to obtain p-hydroxymethylbenzaldehyde. Finally, under appropriate conditions, a strong oxidizing agent, such as potassium permanganate, and an aldehyde group as the carboxyl group, then the target is obtained.
    Second, with p-methylbenzoic acid as the beginning, first with phosphorus trichloride and chlorine gas to make methyl chlorination, to obtain p-chloromethylbenzoic acid. Then it is co-heated with formaldehyde and alkali to introduce hydroxymethyl to generate 1- (hydroxymethyl) -4-carboxybenzene. Then a mild oxidation method, such as Dess-Martin reagent, oxidizes the hydroxymethyl to form an aldehyde group, to obtain.
    Third, starting with p-cresol, first with formaldehyde and acid catalysis, the hydroxymethyl group is introduced into the phenolic hydroxyl group to obtain 4-methyl-2-hydroxybenzyl alcohol. Protect the phenolic hydroxyl group with an appropriate protective group, such as tert-butyl dimethylsilyl. After a mild oxidizing agent, such as PCC, hydroxymethyl oxide as an aldehyde group. Then deprotecting the group, a strong oxidizing agent, such as potassium dichromate, methyl oxide as a carboxyl group, can also be obtained.
    All methods have advantages and disadvantages. The first method has many steps, but the raw materials are common and easy to obtain; the second method is more concise, but the reagents used may be dangerous; the three methods have high requirements for phenol hydroxyl protection, but can precisely control the reaction check point. Practical management, when selected according to the situation.
    What are the precautions for 1- (bromomethyl) -2-fluoro-4-nitrobenzene in storage and transportation?
    Ether groups, hydroxyl groups, carboxyl groups, carbonyl groups and other groups do have many things to pay attention to when storing and transporting.
    Let's talk about ether groups first, their properties are relatively stable, but they should not be taken lightly. Ether compounds are volatile and easy to form peroxides. Therefore, when storing, it should be placed in a cool and ventilated place, away from fire and heat sources, to prevent the risk of explosion caused by the accumulation of volatile gases. Regularly check the sealing of the container to prevent gas from escaping. Peroxides formed by ethers are explosive when heated or impacted. The storage period should not be too long, and inhibitors should be added to prevent the formation of peroxides. During transportation, ensure that the packaging is sturdy to avoid damage to the container caused by collision.
    Hydroxy compounds, many of which are hydrophilic and easy to absorb moisture. Storage should be in a dry environment and sealed to prevent deterioration caused by absorption of moisture in the air. Some hydroxyl-containing substances are corrosive, such as alkali metal salts of certain alcohols, which can cause burns when exposed to skin or mucous membranes. When storing such substances, the container material should be resistant to corrosion and should be well marked. When transporting, follow the transportation rules of corrosive substances and take protective measures.
    Carboxyl compounds, many of which are acidic. Storage requires corrosion-resistant containers, such as glass or specific plastic materials, to prevent reactions with metal containers. Because of its acidity, contact with alkaline substances can react violently, so when storing, it should be placed separately from alkaline substances. During transportation, take good measures to prevent leakage. If leakage occurs, neutralize it with alkaline substances in time.
    Carbonyl compounds, some of which have irritating odor and toxicity. Storage should ensure good ventilation to reduce the accumulation of harmful gases. Some carbonyl compounds are chemically active and easily react with other substances. When storing, pay attention to avoid mixing with easily reactive substances. When transporting, strictly follow the transportation requirements of toxic and hazardous substances to ensure that the packaging is tight to prevent leakage from causing harm to the environment and human body.
    In short, for substances containing such groups, whether stored or transported, they must follow the corresponding specifications and requirements according to their characteristics, and take safety protection measures to ensure the safety of personnel and the environment from pollution.
    What is the approximate market price of 1- (bromomethyl) -2-fluoro-4-nitrobenzene?
    Today's question, what is the approximate market price of (hydroxymethyl) -2-ene-4-carbonyl pyridine? This is a key raw material in the field of fine chemicals, widely used in medicine, pesticides, materials and other industries, and its price is often affected by raw material costs, production processes, market supply and demand and many other factors.
    In the past, if raw materials were abundant and mature, and the market supply was abundant, the price might be relatively stable. However, once raw materials are scarce, such as a key starting material due to the shortage of origin or policy regulation, the manufacturer must increase the price of the product in order to ensure profits. Or the production process encounters a bottleneck, such as the lagging research and development of a new type of catalyst, resulting in low production efficiency and rising costs, which will also drive up prices.
    Looking at the current market, if the demand is strong, such as the pharmaceutical industry developing special new drugs with this as a key intermediate, orders will come in one after another, and the supply will exceed the demand, and the price will rise. On the contrary, if the development of downstream industries is blocked and the demand is weak, the price will be under downward pressure.
    According to industry rumors and recent market monitoring, its price fluctuates between [X] yuan and [X] yuan per kilogram. However, this is only a rough range. The actual price depends on the quality, purity, number of transactions and bargaining power of buyers and sellers at the time of specific transactions. Purchasers should look for more suppliers to compare prices and quality in order to obtain a suitable price.