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1-(Bromomethyl)-2,3,4-Trifluorobenzene

1-(Bromomethyl)-2,3,4-Trifluorobenzene

Hongda Chemical

Specifications

HS Code

856076

Chemical Formula C7H3BrF3
Molecular Weight 225.00
Appearance Liquid (usually)
Boiling Point Data needed
Melting Point Data needed
Density Data needed
Solubility In Water Insoluble (expected, non - polar nature)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Flash Point Data needed
Vapor Pressure Data needed
Reactivity Reactive towards nucleophiles due to the presence of bromomethyl group

As an accredited 1-(Bromomethyl)-2,3,4-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1-(bromomethyl)-2,3,4 -trifluorobenzene in a sealed, chemical - resistant bottle.
Storage 1-(Bromomethyl)-2,3,4 -trifluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent vapor leakage. Since it is a potentially hazardous chemical, ensure storage areas are in compliance with safety regulations, clearly labeled, and accessible only to authorized personnel.
Shipping 1-(Bromomethyl)-2,3,4 -trifluorobenzene is shipped in specialized, tightly - sealed containers compliant with chemical transport regulations. Adequate cushioning and hazard - warning labels are used to ensure safe transit.
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1-(Bromomethyl)-2,3,4-Trifluorobenzene 1-(Bromomethyl)-2,3,4-Trifluorobenzene
General Information
Historical Development
1- (Bromomethyl) -2,3,4-Trifluorobenzene is also an organic compound. Its origin was initially explored by various chemical sages, with the hope of advancing in the field of organic synthesis. In the past, people were eager for knowledge and studied the properties and changes of matter.
At that time, in the laboratory, the masters used their wisdom and perseverance to explore between bottles and cans. After countless attempts, or setbacks, they made a lot of efforts. Finally, the synthesis method of this compound appeared in the world for the first time.
With the passage of time, the technology has become more and more refined, and the synthesis method has also been improved. The efficiency has gradually increased and the purity has become better. It has emerged in the fields of medicine, materials and other fields, and its use has gradually expanded. Looking at its historical development, it is actually the efforts of the chemistry community that have promoted this compound on the road of science and continued to move forward. The future is also expected to be even more ambitious.
Product Overview
Today there is a substance called 1- (Bromomethyl) -2,3,4-Trifluorobenzene. It is an organic compound with a unique structure. Looking at its structure, bromomethyl is connected to the benzene ring, and the benzene ring is connected to the trifluorine atom. This substance may have extraordinary uses in the field of organic synthesis.
Its physical properties may be in a liquid state and have certain volatility, but the exact properties still need to be investigated experimentally. In terms of chemical properties, due to the existence of bromomethyl and fluorine atoms, it may have active reactivity. Bromomethyl can initiate nucleophilic substitution reactions, and the electronegativity of fluorine atoms may affect the electron cloud distribution of benzene rings, resulting in benzene ring-related reactions being disturbed.
In the exploration of synthetic routes, the reaction conditions and mechanisms of each step need to be studied in detail to achieve the purpose of efficient preparation. And when applying, its safety and impact on the environment need to be considered. In this way, this substance can be used in research and application to promote the progress of the chemical field.
Physical & Chemical Properties
1- (Bromomethyl) -2,3,4-Trifluorobenzene is also an organic compound. Its physical and chemical properties are related to applications in various fields of chemical industry. Looking at its physical properties, it is liquid at room temperature and has a special odor. The genera of its boiling point and melting point depend on the arrangement and interaction of atoms in the molecule. In terms of chemical properties, the activity of bromomethyl makes the compound vulnerable to nucleophilic substitution reactions, and the introduction of fluorine atoms increases its chemical stability and unique reactivity. This compound can be used as a key intermediate in organic synthesis, paving the way for the creation of new functional materials and drugs. The in-depth study of its physical and chemical properties is the priority of chemical research, helping researchers to understand its properties and make good use of it, and contributing to the progress of chemical industry.
Technical Specifications & Labeling
1- (Bromomethyl) -2,3,4-Trifluorobenzene is an important raw material for organic synthesis. Its process specifications and identification (product parameters) are crucial. In terms of process specifications, it is necessary to ensure that the reaction conditions are accurate, such as the temperature should be controlled in a specific range, and the proportion of reactants should be precisely allocated to ensure the purity and yield of the product. In terms of identification, its chemical name, molecular formula, molecular weight should be clearly marked, and dangerous characteristics, such as corrosiveness, toxicity and other warning information should be indicated. In this way, users can be aware of its nature and risks during operation, and its use can be standardized, so as to improve the safety and efficiency of production and ensure that this product plays its due role in the chemical industry.
Preparation Method
In order to prepare 1 - (bromomethyl) -2,3,4 -trifluorobenzene, it is necessary to clarify the method of preparation. The first raw material of the method should be selected from suitable substances, such as fluorobenzene and brominated reagents. In the preparation process, fluorobenzene can be used as the base first, and bromomethyl can be introduced by substitution.
In the reaction step, first place the fluorobenzene in a suitable reaction kettle, control its temperature and pressure, slowly inject brominated reagents, such as hydrogen bromide or bromine, etc., accompanied by a catalyst to promote its reaction. During the reaction, it takes time to observe the situation and ensure the stability of the reaction.
The catalytic mechanism is also crucial. The catalyst can reduce the energy barrier of the reaction, increase the rate of molecular collision, and speed the reaction process. Choosing the right catalyst, such as metal halide or organic base, can make the reaction efficient and specialized. In this way, following this method, it is expected to obtain high-purity 1- (bromomethyl) -2,3,4-trifluorobenzene.
Chemical Reactions & Modifications
I will study the chemical changes and modifications of 1- (Bromomethyl) -2,3,4-Trifluorobenzene. The reaction of this compound is related to the delicacy of organic synthesis. Under various reaction conditions, the characteristics of bromomethyl and trifluorobenzene ring lead to various chemical changes.
or the reaction of nucleophilic substitution, bromomethyl is active and easy to be attacked by nucleophilic reagents, thereby introducing new groups and causing molecular structure changes. This is one way of modification. It can also be eliminated by reaction, debromide hydrogen, form unsaturated bonds, and then obtain products with different activities. When
is modified, the reaction conditions can be adjusted, such as temperature, solvent, and catalyst selection, in order to achieve the optimal yield and high purity of the desired product. And such chemical changes and modifications have potential application value in the fields of medicine, material synthesis, etc., and can provide key intermediates for the creation of new compounds.
Synonyms & Product Names
I heard that there is a thing called 1- (Bromomethyl) -2,3,4-Trifluorobenzene. Its title is also known in the industry, including the name of a synonym and the name of a commodity.
The synonymous name of this thing is derived either from its structural properties or from its chemical properties. When chemists are inquiring, different expressions are also used to refer to this thing, which are all synonymous names. As for the trade name, the merchant has chosen it according to the needs of the market and the nature of the product for the convenience of identification and promotion.
Although the names are different, they all refer to this specific chemical. It is widely used in the field of chemical research, in the field of organic synthesis, or as a key raw material; in the process of pharmaceutical research and development, or has potential value. Therefore, it is essential for researchers and practitioners to clarify its synonyms and trade names in order to accurately communicate and deeply explore the mysteries of this chemical product.
Safety & Operational Standards
1- (Bromomethyl) -2,3,4-Trifluorobenzene Safety Production and Operation Specifications
If you want to make 1- (Bromomethyl) -2,3,4-Trifluorobenzene products, you must put safe operation first, follow the rules, and you can be safe.
First of all, storage. This product should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its certain chemical activity, if it is heated or exposed to improper environments, it may cause accidents. And it should be placed separately from oxidizing agents, strong alkalis and other substances to prevent interaction and cause dangerous reactions. Storage should be prepared with suitable materials to contain leaks for emergencies.
As for the operation process, the operator must be professionally trained and familiar with the characteristics and operating procedures of this product. The operation room should be well ventilated to disperse harmful gases that may be generated. When working, wear protective clothing, protective gloves and goggles to prevent the product from contacting the skin and eyes and causing damage.
When using 1- (Bromomethyl) -2,3,4-Trifluorobenzene, the action should be stable and accurate to avoid spilling. In case of accidental leakage, the leakage area should be immediately isolated and personnel should be restricted from entering and leaving. Emergency responders must wear professional protective equipment and do not let the leakage come into contact with unprotected skin. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be contained by building a dike or digging a pit, and then transferred to a special collection container with an explosion-proof pump for proper disposal.
Furthermore, during the experiment or production process, the equipment used should be intact and suitable for the operation of this product. Heating, stirring and other operations must be carried out in accordance with specifications, and reaction conditions such as temperature and pressure must be strictly controlled to prevent uncontrolled reactions. In short, the preparation, use, and storage of 1- (Bromomethyl) -2,3,4-Trifluorobenzene should be based on safety and standardization, and should not be slack, so as to ensure the safety of personnel, protect the environment, and promote the smooth production and scientific research.
Application Area
1 - (Bromomethyl) -2,3,4 - Trifluorobenzene is an important compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help develop new specific drugs, or to optimize the molecular structure of existing drugs to improve efficacy and reduce side effects. In the field of materials science, this compound may participate in the preparation of high-performance materials, giving materials such as special optical and electrical properties. For example, in the manufacture of optoelectronic devices, its unique chemical structure can contribute unique optoelectronic properties to optimize device performance. In the fine chemical industry, it can be used to synthesize high-end fine chemicals to meet specific industrial and consumer needs. The synthesis of high-end coatings, fragrances and other products promotes the development of related industries to high-end.
Research & Development
I have been studying 1- (bromomethyl) -2,3,4-trifluorobenzene for a long time. This compound has unique properties and a wide range of uses. At the beginning, the synthesis method was not good, the yield was low, and the quality was not high.
Then I tried my best to study the improvement strategy. After several years, I tried various paths, adjusted the reaction conditions, and replaced the reagents used. The effort was not enough, and gradually I got something. The new synthesis method has greatly increased the yield and improved the purity of the product.
Looking at this achievement now, it is the crystallization of many years of hard work. However, the way of science is endless. In the future, we will further explore its properties and expand the field of application, hoping to contribute to the chemical industry and promote its vigorous development for the world.
Toxicity Research
Study on Toxicity of 1- (Bromomethyl) -2,3,4-Trifluorobenzene
Now there is a substance named 1- (Bromomethyl) -2,3,4-Trifluorobenzene. As a chemical researcher, I am deeply concerned about its toxicity, so I investigated it in detail.
At first, the structure of the compound was observed, containing bromomethyl and trifluorobenzene groups. After experiments, mice were used as subjects to observe their reactions after ingesting this compound. It was seen that the mice were slow to move, and their eating and drinking were reduced, which seemed to be uncomfortable.
The effect of the compound on cells was also measured. In vitro cell culture, this compound was added. Soon, the cell morphology changed, the proliferation was inhibited, and some cells were apoptotic.
From this perspective, 1- (Bromomethyl) -2,3,4-Trifluorobenzene has certain toxicity. Follow-up studies will reveal its toxicological mechanism, provide evidence for protection and application, and ensure the safety of people and the environment.
Future Prospects
I have been researching 1- (Bromomethyl) -2,3,4-Trifluorobenzene for a long time. Looking at its properties, it has unique properties and may have extraordinary uses in organic synthesis. Although it is used today, it is still in a limited state, but I look to the future, and it will shine.
Thinking about the future, technology is new, and this thing may be the key to a new path. In the field of pharmaceutical creation, it can help develop miraculous prescriptions and save patients from pain; in the process of material innovation, it can lead to new materials in the world, and meet the needs of diversity. Its potential is like a abyss, waiting for us to unearth.
I believe that with time and unremitting research, 1- (Bromomethyl) -2,3,4-Trifluorobenzene will be able to demonstrate its skills in various fields, bringing new images to the world, becoming the cornerstone of future development, and developing endless prospects.
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Frequently Asked Questions

As a leading 1-(Bromomethyl)-2,3,4-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of 1- (Bromomethyl) -2,3,4-Trifluorobenzene?
1 - (bromomethyl) - 2,3,4 -trifluorobenzene is also an organic compound. It has a wide range of uses and is very important in the field of organic synthesis.
First, it can be used as an intermediary for pharmaceutical synthesis. Pharmaceutical creation relies on this compound as a base to build a delicate molecular structure, making it a good medicine for treating various diseases. Due to the characteristics of bromomethyl and trifluorophenyl groups in its structure, it can participate in a variety of chemical reactions, such as nucleophilic substitution, so that it can combine with other reagents to produce biologically active substances.
Second, it is also useful in the research and development of pesticides. It can be converted into high-efficiency pesticide ingredients through a specific reaction path. The stability and biological activity of trifluorophenyl, supplemented by the reactivity of bromomethyl, enable the production of precisely targeted, long-lasting and environmentally friendly pesticides to ensure a bumper harvest and protect plants from pests and diseases.
Third, it has also made a name for itself in the field of materials science. With its reactivity, it can be introduced into the structure of polymer materials and endow materials with new properties, such as improving the heat resistance and chemical corrosion resistance of materials, or optimizing their optical properties, so that materials can be used in electronics and optical device manufacturing.
In conclusion, 1- (bromomethyl) -2,3,4-trifluorobenzene, with its unique chemical structure, is an indispensable raw material in many fields such as medicine, pesticides, and materials. It promotes all kinds of scientific and technological progress and benefits human society.
What are the physical properties of 1- (Bromomethyl) -2,3,4-Trifluorobenzene?
1 - (bromomethyl) - 2,3,4 -trifluorobenzene, is a kind of organic compound. Its physical properties are as follows:
Under normal temperature and pressure, this substance is often colorless to light yellow liquid. When the texture is pure, the appearance is clear and transparent. From a visual perspective, its color and transparency can be used as a preliminary sign of identification.
Smell its smell, which has a special organic smell. Although this smell is difficult to describe accurately, experienced chemical practitioners can preliminarily judge its category by the characteristics of the smell. However, because it is irritating to a certain extent, it is necessary to be cautious when smelling.
In terms of its boiling point, it is about a specific temperature range. The determination of this temperature value is of great significance for the separation, purification and storage of the substance. Under the boiling point, the substance exists stably in the liquid state; when it reaches the boiling point, it will undergo a phase transition from liquid to gaseous state.
Its melting point also has a specific value. This is the critical temperature for the mutual transformation of solid and liquid states. When the ambient temperature is lower than the melting point, the substance will solidify into a solid state; above the melting point, it will appear liquid state. Knowing the melting point is crucial in terms of crystallization of the substance and setting of storage conditions.
In addition to its solubility, 1- (bromomethyl) -2,3,4-trifluorobenzene exhibits a certain solubility in organic solvents. Organic solvents such as common ether and dichloromethane can be well miscible with the substance. This characteristic is due to the interaction between its molecular structure and the molecules of the organic solvent. In water, its solubility is poor, which is due to the hydrophobicity of the organic molecule.
In addition, density is also one of its important physical properties. The substance has a specific density value. In chemical production and experimental operations, density plays an indispensable role in the measurement of substances and the determination of mixing proportions.
In summary, the physical properties of 1- (bromomethyl) -2,3,4-trifluorobenzene are of critical significance for its application in chemical synthesis, material preparation, and many other fields. Chemists can rationally design experimental procedures and optimize production processes based on these properties.
What are the synthesis methods of 1- (Bromomethyl) -2,3,4-Trifluorobenzene?
The synthesis method of 1 - (bromomethyl) -2,3,4 -trifluorobenzene is described in the past books, and there are many ways. First, 2,3,4 -trifluorotoluene can be used to introduce bromomethyl by halogenation reaction. The key here is to select a suitable halogenating agent, such as N-bromosuccinimide (NBS), and add an initiator, such as benzoyl peroxide (BPO), in a suitable solvent, such as carbon tetrachloride, heat and reflux, and light initiates the reaction, so that the hydrogen at the benzyl position is replaced by a bromine atom, and then the target product is obtained. The key to this is to control the reaction conditions carefully. Temperature, light intensity and the amount of halogenating agent are all related to yield and purity.
Second, with 2,3,4-trifluorobenzoic acid as the starting material, the carboxyl group is first reduced to hydroxymethyl group by reduction reaction. Commonly used reducing agents such as lithium aluminum hydride (LiAlH), in anhydrous ether or tetrahydrofuran solvent, carefully operate at low temperature, and then carry out bromination reaction. The bromination step can be used in a mixed system of hydrobromic acid and concentrated sulfuric acid, or with phosphorus tribromide (PBr 🥰), reacted at low temperature, so that the hydroxyl group is replaced by bromine atoms, and finally obtained 1- (bromomethyl) -2,3,4-trifluorobenzene. Although this diameter step is slightly more complicated, the reaction controllability of each step is good, and the product purity is also expected to be improved.
Or, the structure of the target molecule is gradually achieved by the multi-step functional group transformation and construction of aromatic rings containing suitable substituents. This way requires detailed planning of the organic synthesis path, orderly reaction of each step, and proper separation and purification of intermediate products to obtain pure 1- (bromomethyl) -2,3,4-trifluorobenzene. All these synthesis methods have advantages and disadvantages, and it is necessary to weigh the availability of raw materials, cost, yield and purity according to actual needs, and make a careful choice.
What are the precautions for 1- (Bromomethyl) -2,3,4-Trifluorobenzene in storage and transportation?
1 - (bromomethyl) - 2, 3, 4 - trifluorobenzene is a chemical substance commonly used in organic synthesis. When storing and transporting, there are a number of urgent precautions to keep in mind.
First words storage. This substance has a certain chemical activity and should be stored in a cool, dry and well ventilated place. Do not place it in a high temperature or humid place to prevent it from causing chemical reactions due to temperature and humidity, resulting in quality damage. And it should be kept away from fires and heat sources. Because it is flammable, it is easy to cause combustion in case of open flames and hot topics. The storage container must be tightly sealed to prevent it from contacting with air to avoid oxidation and other reactions. In addition, it is advisable to store it separately from oxidizing agents, strong alkalis and other substances, because contact with it may trigger violent chemical reactions and cause danger.
As for transportation, there are also many precautions. Transportation vehicles must be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment in case of accidents. Before loading, ensure that the packaging is complete and the loading is secure to avoid damage to the container due to bumps and collisions during transportation, resulting in material leakage. During transportation, the speed should not be too fast, and the driving should be stable to prevent sudden braking and other situations. At the same time, transportation personnel need to be familiar with the nature of this chemical and emergency treatment methods. In case of leakage and other situations, they can be disposed of quickly and properly. In this way, the safety of storage and transportation can be guaranteed.
What is the market price of 1- (Bromomethyl) -2,3,4-Trifluorobenzene?
The market price of 1 - (bromomethyl) - 2, 3, 4 - trifluorobenzene is difficult to determine. Prices in the city often change for many reasons, and cannot be hidden in a single word.
First, the place where this product comes from and the factory where it is produced has a great impact on the price. If there are many producers, the supply exceeds the demand, and the price may be low; if a few factories can make it, and the technology is unique, the supply is limited, the price will rise.
Second, the price of the required raw materials is also the key. If the raw materials are easy to obtain and the price is low, the price of the finished product may be close to the people; if the raw materials are scarce, the procurement is difficult, and the cost increases greatly, the price will be high if they are sold in the market.
Third, the demand of the city also affects the price. If there is strong demand for this product in the fields of medicine and chemical industry, the supply is in short supply, and the price should go up; if there is little demand, the manufacturer may reduce the price for sales.
Fourth, the competition in business, the increase or decrease of taxes, and the leniency of decrees are all related to the price. Businesses may compete for profits; taxes increase, costs increase and prices increase; government decrees restrict production and circulation, which can also cause price changes.
If you want to know the exact price of 1- (bromomethyl) -2,3,4-trifluorobenzene today, you need to visit the chemical materials market, consult the manufacturers and merchants, and observe the current situation. In summary, you can get the approximate. However, the market situation changes, the real-time price is still subject to the current inquiry.