1-Bromo-4-(Perfluoroethoxy)Benzene

Hongda Chemical

Specifications

HS Code	811068
Chemical Formula	C8H4BrF5O
Molecular Weight	305.01
Appearance	Colorless to light yellow liquid
Boiling Point	Around 180 - 185°C
Density	1.7 - 1.8 g/cm³
Solubility	Insoluble in water, soluble in organic solvents like dichloromethane
Vapor Pressure	Low vapor pressure at room temperature
Stability	Stable under normal conditions, but reactive with strong oxidizing agents
Odor	Characteristic organic odor

As an accredited 1-Bromo-4-(Perfluoroethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 1 - bromo - 4 - (perfluoroethoxy)benzene packaged in a sealed glass bottle.
Storage	1 - Bromo - 4 - (perfluoroethoxy)benzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. It should be kept in a tightly - sealed container, preferably made of materials resistant to chemical corrosion. Store it separately from oxidizing agents and reactive substances to prevent potential chemical reactions.
Shipping	1 - bromo - 4 - (perfluoroethoxy)benzene is shipped in specialized, leak - proof containers. Shipment adheres to strict chemical transport regulations, ensuring proper handling and safety during transit to prevent any environmental or safety risks.

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General Information

Historical Development

1 - Bromo - 4 - (Perfluoroethoxy) Benzene is also an organic compound. Its research and development process is really related to the evolution of chemical technology. In the past, organic synthesis was not as sophisticated as it is today, and researchers worked hard to explore the preparation of fluorinated compounds. At first, the introduction of benzene rings to fluorinated groups encountered many difficulties, the reaction conditions were harsh, and the yield was also low.
However, scientific researchers worked tirelessly, and new reagents and new methods emerged with the gradual enrichment of chemical theory. When synthesizing 1 - Bromo - 4 - (Perfluoroethoxy) Benzene, chemists improved the reaction path, optimized the catalyst, and made the reaction conditions milder and the yield improved. Since its difficult start, it has been able to synthesize this compound relatively efficiently today, witnessing tremendous progress in the field of chemical synthesis and paving the way for the subsequent development of organofluorine chemistry.

Product Overview

1 - Bromo - 4 - (Perfluoroethoxy) Benzene, also an organic compound. Its color is pure and uniform, and its shape is like a clear liquid. The preparation of this compound requires a delicate method and a rigorous process. It can be obtained by using fluoroethane and bromobenzene as a group, accompanied by a suitable catalyst, and controlled by precise temperature and pressure.
Its properties are stable, and it is not easy to change in common chemical environments. In the field of organic synthesis, it has a wide range of uses. It can be used as an intermediate, which is the cornerstone of the creation of other types of complex organic molecules. Its unique structure, the benzene ring is connected to the fluoroethoxy group, endowing it with special physical and chemical properties, which is conducive to the research and development of new materials. It may have extraordinary effects in the pharmaceutical, electronics, and other industries, and can contribute to the progress of related fields. It is indeed a compound that cannot be ignored in organic synthesis.

Physical & Chemical Properties

1 - Bromo - 4 - (Perfluoroethoxy) Benzene is also an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, this substance may be a colorless liquid with a special odor. Its boiling point and melting point are fixed, depending on its state of existence. The boiling point is related to the difficulty of gasification; the melting point is determined by the temperature of solid-liquid transformation.
In terms of its chemistry, its structure contains bromine atoms and perfluoroethoxy groups, so it has unique reactivity. Bromine atoms can participate in reactions such as nucleophilic substitution, while perfluoroethoxy groups affect the polarity and stability of molecules. It has good solubility in organic solvents, and this property is also related to its performance in many chemical reactions. Exploring the physical and chemical properties of this substance can provide a solid foundation for its synthesis and application, and is of great significance in the fields of organic synthesis.

Technical Specifications & Labeling

1 - Bromo - 4 - (Perfluoroethoxy) Benzene is also an organic compound. Its process specifications and identification (product parameters) are crucial. In terms of process specifications, the synthesis method needs to precisely control the reaction conditions, such as temperature, pressure, and the proportion of reactants. The choice of reaction solvent is also important, and it must be in line with the reaction characteristics to make the reaction smooth.
In terms of identification, the product label should specify its chemical name, molecular formula, molecular weight and other basic parameters. And there must be clear warning labels to inform its possible hazards, such as toxicity, corrosiveness, etc. In this way, the safety of this product during production, storage and use must be ensured, and accurate information can be provided to users to help them use it rationally.

Preparation Method

In order to prepare 1 - Bromo - 4 - (Perfluoroethoxy) Benzene, the method of preparation should be studied in detail. First, take an appropriate amount of benzene and use it as the base. Another bromide and a reagent containing perfluoroethoxy are prepared.
In the reaction step, first place benzene and catalyst in a reactor, control the temperature to an appropriate temperature, slowly add bromide to promote the reaction and generate bromobenzene. Then, in another reaction vessel, mix bromobenzene with a reagent containing perfluoroethoxy, adjust the reaction conditions, such as temperature, pressure and reaction time, so that it can fully react to obtain 1 - Bromo - 4 - (Perfluoroethoxy) Benzene.
In order to promote the reaction, set up a check and balance mechanism. If the reaction is too slow, the amount of catalyst can be increased; if the reaction is too fast, it is appropriate to adjust the temperature and slow down. In this way, 1-Bromo-4 - (Perfluoroethoxy) Benzene products with higher purity can be obtained.

Chemical Reactions & Modifications

There is now a chemical substance, named 1 - Bromo - 4 - (Perfluoroethoxy) Benzene. In the chemical reaction and modification, it is very important.
The reactant should use suitable reagents and conditions to change its molecular structure. If a specific catalyst is selected and adjusted to an appropriate temperature and pressure, the bromine atom or ethoxy group will undergo a reaction such as substitution and addition to form a new compound.
As for modification, other functional groups can be introduced to change its physical and chemical properties. If a polar group is added, its solubility can be increased; the symmetry of the molecule can be changed, or its melting point and boiling point can be changed. Our chemical researchers should carefully study this reaction and modification method in order to make new discoveries and applications in various fields such as chemical engineering and materials, so that this compound can be used to its full potential and benefit the world.

Synonyms & Product Names

1 - Bromo - 4 - (Perfluoroethoxy) Benzene is unique in the field of chemical research. Its synonymous name and commodity name are valued by our researchers.
The synonymous name depends on its structural characteristics or follows the research track of the past. This name can accurately describe its chemical composition, so that colleagues in the academic community can know its molecular structure at a glance.
As for the name of the commodity, it is born in response to market circulation and industrial application. In the chemical trading market, a clear and unique commodity name allows buyers and sellers to accurately identify this product and promote its application in industrial production and other fields.
Our researchers explore this object, and the synonym and trade name are like keys, which help us open the door to in-depth research, gain insight into its chemical nature, and explore its more potential uses, contributing to the development of chemistry and the progress of industry.

Safety & Operational Standards

1 - Bromo - 4 - (Perfluoroethoxy) Benzene Safety and Operation Code
1 - Bromo - 4 - (Perfluoroethoxy) Benzene is an important substance in chemical research. Its safety and operation standards are of paramount importance, which is related to the safety of the researcher and the smooth operation of the experiment.
For storage, this substance should be placed in a cool, dry and well-ventilated place. Due to its nature or sensitivity to environmental factors, moisture and high temperature can cause it to deteriorate or cause dangerous reactions. Therefore, the storage place must be kept away from fire, heat and oxidants to prevent accidents.
When operating, the researcher must wear appropriate protective equipment. Protective clothing can prevent it from contacting the skin, while protective glasses can protect the eyes from splashing damage. It is particularly crucial that the operation should be carried out in a fume hood, which can quickly remove volatile gaseous substances to avoid their accumulation in the experimental environment and reduce the risk of poisoning.
During use, use this substance with caution. Measure the exact amount to prevent waste and excessive danger. If it is accidentally spilled, it should be cleaned up immediately according to the established procedures. Cover with adsorbent material to avoid its spread, and then properly collect and dispose of the waste according to regulations.
Furthermore, the researcher should be familiar with the physical and chemical properties of the substance before the experiment. Knowing its melting point, boiling point, solubility, etc. can help predict experimental phenomena and possible problems, so as to prepare countermeasures in advance.
In short, in the research operation of 1 - Bromo - 4 - (Perfluoroethoxy) Benzene, strict adherence to safety and operating standards can ensure the safety of the experiment and promote the smooth progress of the research.

Application Area

1 - Bromo - 4 - (Perfluoroethoxy) Benzene is also a material for chemical processing. Its use, in the field of production, can be used to make special effects, so as to improve the quality of diseases. Due to its unique chemical properties, it can create subtle reactions, and create molecules, so as to eliminate diseases and save people.
In the world of sub-materials, this product also has amazing achievements. It can help create high-performance sub-components, such as semi-high-performance components, etc. Its characteristics can change the performance of the component, make it more sensitive and efficient, and promote the progress of sub-technology.
And in the field of materials, 1 - Bromo - 4 - (Perfluoroethoxy) Benzene can be used as an important angle for synthesizing special materials. Synthetic products, or with low resistance, wear resistance, etc., are used in aviation, automotive, etc., to improve the quality of products.

Research & Development

There is a substance today, named 1 - Bromo - 4 - (Perfluoroethoxy) Benzene. I am a chemical researcher, dedicated to the research and development of this substance.
Study the properties of this substance, related to its structure and characteristics. Observe its reaction rules, observe its changes under different conditions. After many experiments, we know how it interacts with various substances.
As for development, we hope to expand its use. Or in medicine, to help the production of new drugs, to increase efficacy and reduce harm; or in materials, to create special materials, with excellent properties, suitable for special needs.
Although the research journey is difficult, I hold a strong heart and hope to explore its mysteries, so that it can demonstrate extraordinary capabilities in the world, seek well-being for everyone, and promote the progress of chemistry and the prosperity of science and technology.

Toxicity Research

1 - Bromo - 4 - (Perfluoroethoxy) Benzene is also a chemical substance. As a chemical researcher, I should not be careless in observing its toxicity.
Examination of ancient books, in order to clarify its toxicity, it is necessary to use multiple methods. First, the white pigs, guinea pigs and other animals in the room are given different amounts of this substance to measure its physiological properties, such as living, eating, raw, and even the body. The cells are also taken and placed in the culture solution containing this substance to reduce its cytoplasm, proliferation, and apoptosis.
General research, if this substance causes the substance to behave normally, or makes the cells heavy, the toxicity cannot be ignored. However, the study of toxicity is not a one-size-fits-all work, and it needs to be pursued over time and repeatedly, so as to obtain a comprehensive solution, so as to protect people's well-being and safety.

Future Prospects

Prospects of the future, in 1 - Bromo - 4 - (Perfluoroethoxy) Benzene, this product has a lot of potential. Its characteristics are unique, and it has many different properties. In the chemical industry, it is all possible.
Not yet, or it can be used in the field of material synthesis to make a big impact. With its special properties, new materials with excellent properties can be prepared.
Are they resistant, high-resistant materials, or those with special light properties are expected to be developed.
Furthermore, in the process of research and development, there may also be its presence. With its starting materials, it can be cleverly transformed, or special effects can be obtained, saving the world and benefiting the people.
And in the sub-industry, it may be used in the development, to help the development of high-end sub-devices, to promote the progress of science and technology, so that the sub-products that have not been developed are more sophisticated and efficient. In the future, 1 - Bromo - 4 - (Perfluoroethoxy) Benzene will be filled with hope, and it will be a must.

Where to Buy 1-Bromo-4-(Perfluoroethoxy)Benzene in China?

As a trusted 1-Bromo-4-(Perfluoroethoxy)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Bromo-4-(Perfluoroethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of 1-Bromo-4- (Perfluoroethoxy) Benzene?

1-Bromo-4- (perfluoroethoxy) benzene, this substance is widely used. In the field of organic synthesis, it is often used as a key intermediate. Due to the bromine atom and perfluoroethoxy group in its structure, it has unique reactivity. Bromine atoms are highly active and can borrow nucleophilic substitution reactions. They interact with many nucleophilic reagents, such as alcohols and amines, to achieve the construction of carbon-oxygen bonds and carbon-nitrogen bonds, and then synthesize organic compounds with diverse structures.
In the field of materials science, 1-bromo-4- (perfluoroethoxy) benzene also plays an important role. The strong electron absorption and excellent chemical stability of perfluoroethoxy can endow materials with unique properties. For example, introducing it into polymer materials can improve the surface properties of materials, such as reducing surface energy and enhancing the water resistance, oil resistance and antifouling properties of materials.
In addition, in the field of medicinal chemistry, it may be used to create new drugs. By ingeniously modifying its structure, compounds with specific biological activities may be obtained. Drug developers can use the reactivity of this substance to construct pharmacophore combined with biological targets to achieve the purpose of treating diseases.
Furthermore, in the field of electronic chemicals, 1-bromo-4- (perfluoroethoxy) benzene also shows potential application value. With the continuous development of electronic equipment in the direction of miniaturization and high performance, the performance requirements of electronic chemicals are increasing. Its unique chemical structure may bring special electrical properties and thermal stability to electronic chemicals, and play a key role in the preparation of electronic materials.

What are the physical properties of 1-Bromo-4- (Perfluoroethoxy) Benzene?

1-Bromo-4- (perfluoroethoxy) benzene is one of the organic compounds. Its physical properties are very important, and it is related to the application of this compound in many fields.
First of all, its appearance, under normal temperature and pressure, 1-bromo-4- (perfluoroethoxy) benzene is often colorless to light yellow liquid, clear and transparent, without visible impurities, and it has a flowing state. It is like smart water, but it has the characteristics of chemical substances.
Besides its melting point, it has been determined by many experiments that the melting point of this compound is about -20 ° C. At this temperature, 1-bromo-4- (perfluoroethoxy) benzene gradually changes from liquid to solid. The movement of the molecules slows down due to the decrease in temperature, and the arrangement between them tends to be regular and orderly.
The boiling point is also one of the key physical properties. The boiling point of 1-bromo-4- (perfluoroethoxy) benzene is about 170-180 ° C. When the temperature rises to the boiling point, the compound molecule gains a lot of energy and moves more violently, enough to break free from the shackles of the liquid phase and escape into a gaseous state.
In terms of density, its density is about 1.7-1.8 g/cm ³, compared with the density of water 1 g/cm ³, 1-bromo-4 - (perfluoroethoxy) benzene has a higher density. If mixed with water, it will sink to the bottom of the water, and the layers of the two are clearly distinguishable.
Solubility cannot be ignored either. 1-bromo-4 - (perfluoroethoxy) benzene is insoluble in water, because water is a polar molecule, and the polarity of this compound is weak. According to the principle of "similarity and compatibility", the two are difficult to miscible. However, it is soluble in common organic solvents, such as ether, chloroform, dichloromethane, etc. In such solvents, 1-bromo-4- (perfluoroethoxy) benzene molecules interact with solvent molecules and disperse uniformly.
In addition, 1-bromo-4- (perfluoroethoxy) benzene has a certain volatility. At room temperature, some molecules will escape from the liquid surface into the air, emitting a special odor. However, the odor is not strong and pungent, but its potential impact on the environment and human body cannot be ignored.

Is 1-Bromo-4- (Perfluoroethoxy) Benzene Chemically Stable?

The stability of the chemical properties of 1-bromo-4- (perfluoroethoxy) benzene is related to many reasons. In this compound, the bromine atom has a certain activity and can be involved in reactions such as nucleophilic substitution. However, its benzene ring has a certain stability due to the conjugation system. And in the perfluoroethoxy part, the fluorine atom is extremely electronegative, forming a strong electron-absorbing effect, which changes the distribution of molecular electron clouds.
Generally speaking, under common mild conditions, 1-bromo-4- (perfluoroethoxy) benzene is relatively stable. In air, without special conditions, it is not easy to react quickly with oxygen, water vapor, etc. In case of strong nucleophilic reagents, bromine atoms may be replaced, because the attack of nucleophilic reagents on bromine atoms can cause reactions to occur.
And in case of extreme conditions such as high temperature and strong radiation, its chemical bonds may be affected and broken, rearranged and other changes. However, in the conventional environment of general laboratory and industrial production, if there is no specific reagent and condition excitation, this compound can maintain a relatively stable state. However, the specific stability still needs to be fully considered according to the actual environment, contact substances and external conditions.

What is the preparation method of 1-Bromo-4- (Perfluoroethoxy) Benzene?

The preparation method of 1-bromo-4- (perfluoroethoxy) benzene, although the book "Tiangong Kaiwu" does not directly record the preparation method of this specific compound, it can be deduced according to the chemical process ideas and common synthesis concepts contained in it.
To prepare 1-bromo-4- (perfluoroethoxy) benzene, p-bromophenol and perfluorobromoethane can be used as raw materials. Both of these are common materials for organic synthesis. First, in an alkaline environment, the phenolic hydroxyl group of p-bromophenol is prone to lose protons and form phenoxy negative ions, which have strong nucleophilic properties. In perfluorobromoethane, because the bromine atom is connected to the perfluoroalkyl group, the polarity of the carbon-bromo bond is enhanced by the strong electron-absorbing effect of the fluorine atom, so that the carbon atom is partially positively charged and electrophilic. The phenoxy negative ion then attacks the carbon atom of perfluorobromoethane, and the bromine ion leaves, and the nucleophilic substitution reaction generates 1-bromo-4- (perfluoroethoxy) benzene.
When reacting, it is crucial to choose a suitable solvent. Aprotic polar solvents such as N, N-dimethylformamide (DMF) or dimethylsulfoxide (DMSO) are preferred, because they are soluble reactants and stabilize ionic intermediates, which promote The alkaline reagent can be selected from weak bases such as potassium carbonate and sodium carbonate to ensure that the phenolic hydroxyl group is effectively converted into phenoxy anions without unduly affecting the reaction system. At the same time, when temperature control and control are required, moderate heating can increase the reaction rate, but if the temperature is too high, side reactions or raw, so it is often reacted at 50-80 ° C for several hours. The reaction process is monitored by thin layer chromatography (TLC). When the raw material spots disappear, the reaction is completed. After the reaction is completed, pure 1-bromo-4- (perfluoroethoxy) benzene can be obtained through post-treatment processes such as extraction, washing, drying, and distillation.

What are the precautions for storing and transporting 1-Bromo-4- (Perfluoroethoxy) Benzene?

1-Bromo-4- (perfluoroethoxy) benzene is an organic compound. When storing and transporting it, the following matters must be paid attention to:
First, the storage environment should be strictly controlled. It should be placed in a cool, dry and well-ventilated place. This compound can easily decompose when heated, or even cause dangerous conditions, so it must be kept away from fire and heat sources, and the warehouse temperature should not be higher than 30 ° C. At the same time, the air humidity is also the key. If the humidity is too high or the compound deteriorates, the relative humidity should be maintained at 40% - 70%.
Second, the packaging must be solid and reliable. The packaging material used must be able to effectively resist the erosion of 1-bromo-4- (perfluoroethoxy) benzene, such as the use of special corrosion-resistant plastic drums or iron drums lined with special coatings. The packaging seal must be tight to prevent leakage. And the name of the chemical, dangerous characteristics, emergency treatment methods and other key information should be clearly marked on the outside of the package.
Third, the transportation process should be extra cautious. The transportation vehicle must have good ventilation equipment to disperse volatile gases that may leak. This compound is a hazardous chemical, and the transportation personnel should be professionally trained to be familiar with its characteristics and emergency treatment methods. Avoid severe bumps and collisions during transportation to prevent package damage. At the same time, necessary emergency rescue equipment and protective gear must be equipped in accordance with relevant regulations.
Fourth, do not mix with oxidizing substances, alkaline substances and other mixed storage and transportation. 1-Bromo-4 - (perfluoroethoxy) benzene encounters oxidizing substances or causes severe oxidation reactions; contact with alkaline substances may also cause chemical reactions, resulting in danger. Therefore, when storing and transporting, it is necessary to ensure that it is strictly isolated from such substances.