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1-Bromo-4-Nitro-2-(Trifluoromethyl)Benzene

1-Bromo-4-Nitro-2-(Trifluoromethyl)Benzene

Hongda Chemical

    Specifications

    HS Code

    411707

    Chemical Formula C7H3BrF3NO2
    Molar Mass 286.00 g/mol
    Appearance Solid (likely)
    Melting Point Data needed
    Boiling Point Data needed
    Density Data needed
    Solubility In Water Low (organic compound)
    Solubility In Organic Solvents Good (common organic solvents)
    Flash Point Data needed
    Vapor Pressure Data needed
    Pka Data needed
    Logp Data needed

    As an accredited 1-Bromo-4-Nitro-2-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - bromo - 4 - nitro - 2 - (trifluoromethyl)benzene in a sealed glass bottle.
    Storage 1 - Bromo - 4 - nitro - 2 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics, to prevent leakage and contamination.
    Shipping 1 - bromo - 4 - nitro - 2 - (trifluoromethyl)benzene is shipped in properly labeled, corrosion - resistant containers. Shipment follows strict hazardous chemical regulations, ensuring secure handling during transit to prevent any leakage or safety risks.
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    1-Bromo-4-Nitro-2-(Trifluoromethyl)Benzene 1-Bromo-4-Nitro-2-(Trifluoromethyl)Benzene
    General Information
    Historical Development
    1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is an important substance in the study of chemistry today. Tracing back to its source, at the beginning, the academic community had little knowledge of halogenated nitro-aromatic hydrocarbons and trifluoromethyl compounds. However, after years of unremitting research, the method of organic synthesis has been continuously explored and improved.
    First, the organic synthesis technology is not exquisite, and it is difficult to make this substance, and the yield is quite low. However, chemists are determined to study various reaction mechanisms in detail and try various reaction conditions. After repeated trials, a more effective synthesis path was finally obtained. From the initial exploration to the gradual clarification of the reaction process, the preparation of this compound has gradually matured. Its application potential in many fields such as medicine and materials has also been gradually demonstrated, paving the way for future related research. It is a key node in the development of chemistry to lead the academic community to study its characteristics and uses more deeply.
    Product Overview
    1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is also an organic compound. It is a colorless to light yellow liquid with a special odor. The compound has a wide range of uses in the field of organic synthesis and is often used as an intermediate.
    The preparation method may be obtained by a series of reactions such as bromination, nitration and trifluoromethyl of specific aromatic hydrocarbons. During the reaction process, the reaction conditions, such as temperature, ratio of reactants and amount of catalyst, need to be carefully adjusted to ensure the purity and yield of the product.
    The characteristics of 1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene are derived from its molecular structure. The presence of bromine atom, nitro group and trifluoromethyl group endows it with unique chemical activity. In many organic reactions, the reactivity of specific groups can be used to realize the construction of various compounds, which makes great contributions to the development of organic synthetic chemistry.
    Physical & Chemical Properties
    1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is also an organic compound. Its physical and chemical properties are particularly important, related to the characteristics and uses of this compound. In terms of physical properties, this substance is usually in a solid state, with a specific melting point and boiling point. Its melting point is about [specific value], and its boiling point is about [specific value]. These data are obtained by precise experimental determination. Looking at its chemical properties, it is active because of the functional groups such as bromine, nitro and trifluoromethyl in its molecular structure. Bromine atoms can undergo substitution reactions, and nitro groups have strong electron-absorbing properties, which affect the electron cloud distribution of molecules, reducing the density of electron clouds in benzene rings, making it difficult for electrophilic substitution reactions to occur. The presence of trifluoromethyl enhances the stability and hydrophobicity of the molecule. This compound is widely used in the field of organic synthesis. Due to its unique physical and chemical properties, it can be used as a key intermediate for the preparation of many high-value-added fine chemicals.
    Technical Specifications & Labeling
    1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene This product, its technical regulations and identification (commodity parameters) are the key. If you want to make this product, you must first understand the precise selection of its raw materials, and the proportion is accurate. The materials used must be of high purity before they can be included in the process.
    In the process, the control of the fire and the inspection of the time need to be fine. The quality is variable when the temperature is high, and the quality is not complete when it is short. And the reaction device should also be clean and suitable to avoid noise.
    As for the identification (commodity parameters), its purity geometry and impurities must be detailed. On the packaging, it should also be marked with the name, sex, and danger, so that the user can understand. In this way, the good products of 1-Bromo-4-Nitro-2 - (Trifluoromethyl) Benzene can be used in the field of chemical industry for their needs and performance.
    Preparation Method
    To prepare 1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene, the raw materials and production process, reaction steps and catalytic mechanism are the key. Appropriate aromatics can be taken first, supplemented by reagents containing bromine, nitro and trifluoromethyl. At the beginning of the reaction, carefully adjust the temperature, pressure and catalyst dosage. For example, with a high-efficiency catalyst, at a specific temperature, aromatics and brominating reagents interact skillfully to introduce bromine atoms. Then, carefully add nitrogenation reagents, and through a series of reaction steps, precisely introduce nitro groups into the appropriate position. Finally, trifluoromethyl is introduced by a special process. At each step, it is necessary to strictly control the reaction conditions, pay attention to the subtle changes in the reaction process, in order to achieve the purpose of efficient and high-quality preparation of this product, and pay attention to the rational use of the catalytic mechanism to promote the smooth progress of the reaction and improve the yield and purity of the product.
    Chemical Reactions & Modifications
    Today, there is a compound called 1-Bromo-4-Nitro-2 - (Trifluoromethyl) Benzene. In the field of chemical research, its chemical reaction and modification are very important. The reaction of this compound is often related to the changes of substitution and addition, and the conditions are different, and the products are also different.
    To find a way to modify it, it is necessary to understand its molecular structure and chemical properties. After many experimental investigations, it may be possible to introduce specific groups and change their electron cloud distribution to change its chemical activity.
    In chemical reactions, temperature, solvent and catalyst are all key factors. The rise and fall of temperature can speed or slow down the reaction process; the difference of solvents also affects the direction and rate of the reaction; the addition and subtraction of catalysts can change the activation energy of the reaction and promote the efficient progress of the reaction.
    The study of the chemical reaction and modification of this compound can pave a feasible path for the creation of new materials, drug research and development, and other fields, contributing to the vigorous development of the chemical field.
    Synonyms & Product Names
    1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene, this substance is very important in our chemical research. Its synonymous name is also studied by us in detail.
    Considering its synonyms, or according to its structural properties, it is called. This substance contains bromine (Bromo), nitro (Nitro) and trifluoromethyl (Trifluoromethyl), and the order of the groups on the benzene ring is established, so it is also combined with its position and group name. And because it is an organic halide, or it is added with the name of halogenated nitrobenzene, although the details are slightly different, it refers to this substance.
    As for the trade name, the industry may order it according to its use, quality, and production process. Those who highlight its high purity are important to highlight its essence in the trade name; those who use it as a selling point for a specific field also see its specialization in the name. This is all for the convenience of business transactions and product differentiation. Our chemical researchers are indispensable in the distinction between synonyms and trade names, which is of great benefit to accurate communication and research promotion.
    Safety & Operational Standards
    1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is an important chemical. There are many key points to be paid attention to in terms of its safe production and operation practices.
    The first word is safe, this chemical is dangerous. Its bromine, nitro and trifluoromethyl structures make it toxic, irritating and corrosive. When storing, be sure to choose a dry, cool and well-ventilated place away from fire, heat and oxidants. It must be contained in a sealed container to prevent leakage, and the container should be clearly marked with the name of the chemical and the hazard warning.
    As for the operating specifications, operators must be professionally trained and familiar with their nature and safe operation procedures. Appropriate protective equipment must be worn during operation, such as protective gloves, goggles and gas masks, to avoid skin contact and inhalation. Operating in a fume hood can effectively reduce the accumulation of harmful gases.
    Furthermore, if a leak occurs unfortunately, do not panic. When evacuating irrelevant personnel quickly, isolate the leakage area. In the event of a small leak, it can be absorbed by inert materials such as sand and vermiculite, and then properly collected in a special container. A large number of leaks need to be built embankments or dug for containment, and transferred to a tanker or a special collector with an explosion-proof pump, recycled or transported to a waste disposal site for disposal.
    When performing the reaction operation, strictly control the reaction conditions. According to its chemical characteristics, precisely control the temperature, pressure and reaction time to prevent the reaction from getting out of control. And the experimental equipment must be checked regularly to ensure its airtightness and safety.
    In short, the safety and operation standards of 1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene are the key to ensuring the safety of personnel and the smooth progress of experiments and production, and must not be taken lightly.
    Application Area
    1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is an important chemical substance. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new drugs. With its unique chemical structure, it participates in the construction of drug molecules, or affects the activity and selectivity of drugs and other key properties. In the field of materials science, it also has potential. It can be used to prepare materials with special properties, such as improving the electrical and optical properties of materials. Because of its fluorine, bromine and other special atoms, it gives it unique chemical activity and physical properties, which can add special functions to materials. The application of this substance is like opening up new paths in many fields, leading related research and industries to new heights.
    Research & Development
    In the field of chemical industry, new substances are emerging one after another. 1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is the object of my dedicated research. I began to observe its properties, analyze its structure, and want to understand its state in various reactions.
    Study the method of its preparation, or there may be new ways to explore, hoping to optimize the process, increase its yield, and reduce its cost. Looking at its application in synthesis, a new chapter can be opened, hoping to use it as a basis to expand the new territory of chemical synthesis.
    I always think, if I get an exquisite method to control its reaction path, it will be able to develop its potential. With time, advanced technology will enable this product to make progress in the fields of medicine and materials, contributing to the development of the chemical industry, so as to promote its flourishing and lead the trend of research and development.
    Toxicity Research
    Toxicity Study of 1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene
    Husband 1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is also a chemical substance. In today's world, it is used in the field of work and use it. However, the study of its toxicity cannot be ignored.
    At the beginning, it was used as a chemical substance, and it was cast with this substance. Not long after, the chemical substance stopped acting normally. Or restlessness, or listlessness. And analyzing its body, the liver and the body, all have the appearance of the body. The cells of the liver change shape and function.
    As a result, it is applied in the tube. The proliferation of the cell is inhibited, and the apoptosis is affected. It is reasonable to investigate that this substance or the generation of the stem cell is the expression of its genes.
    Therefore, 1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene is toxic, and it can be harmful to living organisms. Those who use this substance should be cautious to prevent it from being damaged.
    Future Prospects
    I tried to study the chemical industry, and I thought about the future prospects of 1 - Bromo - 4 - Nitro - 2 - (Trifluoromethyl) Benzene. Looking at today's world, science and technology are changing day by day, and the chemical field is also changing. This compound has unique properties, or in pharmaceutical research and development, it can be used as a key intermediate to help create new drugs and relieve the pain of patients. In materials science, it may be able to give materials specific properties, such as enhancing their stability and weather resistance. Although it is not widely used at present, with time, the deeper the research and the more advanced the technology, it will be able to show its extraordinary effect. The future is expected to shine brightly in many fields, creating a new situation and creating infinite benefits for our generation of chemical workers. This is the future prosperity we hope for.
    Where to Buy 1-Bromo-4-Nitro-2-(Trifluoromethyl)Benzene in China?
    As a trusted 1-Bromo-4-Nitro-2-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-4-Nitro-2-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1-Bromo-4-Nitro-2- (Trifluoromethyl) Benzene?
    1-Bromo-4-nitro-2- (trifluoromethyl) benzene is also an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
    The creation of Guanfu Pharmaceutical, this compound can be used to construct molecular structures with specific pharmacological activities. Through delicate chemical reactions, it can add functional groups to meet the needs of drug design, and then develop new therapeutic drugs to cure various diseases.
    In the field of materials science, it also has important functions. It can be integrated into polymer materials through polymerization or other chemical modification methods to give the material special properties, such as enhancing its stability, weather resistance, or endowing it with unique optical and electrical properties, suitable for the preparation of various advanced materials, such as photoelectric materials, high-performance engineering plastics, etc.
    The field of pesticide synthesis is also indispensable. With this as the starting material, through series of transformations, high-efficiency, low-toxicity and selective pesticides can be created, which can help agricultural pest control and improve crop yield and quality. Due to the presence of halogen atoms, nitro groups, and trifluoromethyl groups in its structure, it is favored by organic chemists for its unique reactivity and physicochemical properties. During the exploration and development of novel organic synthesis methods, it is often selected as a substrate to expand the boundaries of organic synthesis chemistry and give rise to many innovative synthesis strategies and technologies.
    What are the physical properties of 1-Bromo-4-Nitro-2- (Trifluoromethyl) Benzene?
    1-Bromo-4-nitro-2- (trifluoromethyl) benzene, which has specific physical properties. Its color state is mostly white to light yellow crystalline powder, which looks like fine frost powder and has a light color. The melting point is between 73-77 ° C, which is like a temperature threshold. When it reaches this range, the material state gradually changes. In this temperature range, the solid phase will slowly melt into the liquid phase, just like ice and snow melting when warm.
    In addition, its solubility also has characteristics. Slightly soluble in water, like a hermit in water, it is difficult to melt, as if it is incompatible with water, and the two are clearly defined. However, in organic solvents, such as ethanol and ether, it can dissolve well, just like a wanderer returning home and blending freely. This difference in solubility is due to the difference in its molecular structure and the interaction between solvent molecules.
    In addition, its density and other physical parameters are also important characteristics. The density value is specific, reflecting the degree of close arrangement of molecules, which is of great significance in many applications of substances. It is related to its behavior in different environments. Just like the cornerstone is in a high-rise building, although hidden in it, it is crucial. These physical properties have a profound impact on its application in chemical synthesis, material preparation and other fields. Many reaction conditions and process designs depend on this.
    What is the chemical synthesis method of 1-Bromo-4-Nitro-2- (Trifluoromethyl) Benzene?
    The chemical synthesis of 1-bromo-4-nitro-2- (trifluoromethyl) benzene is a key research in the field of organic synthesis. To obtain this compound, the following steps are often followed.
    First of all, trifluoromethylbenzene is used as the starting material, because its structure already contains trifluoromethyl groups, which lays the foundation for the construction of target molecules. This step is crucial to carry out nitration reaction on trifluoromethylbenzene first. In an appropriate reaction vessel, add an appropriate amount of concentrated sulfuric acid and concentrated nitric acid mixed solution. This mixed acid is a nitrifying agent. Under low temperature and sufficient stirring conditions, slowly add trifluoromethylbenzene dropwise. The low temperature environment can effectively control the reaction rate and avoid excessive side reactions. 4-Nitro-2- (trifluoromethyl) benzene is formed by introducing nitro group at a specific position in the benzene ring through nitration reaction. The principle of this reaction is based on the electrophilic substitution reaction mechanism of the benzene ring, and the nitro positive ion acts as an electrophilic reagent to attack the higher electron cloud density of the benzene ring.
    Then, the bromination reaction is carried out on 4-nitro-2- (trifluoromethyl) benzene. Liquid bromine is used as the brominating agent, and an appropriate amount of iron powder or iron tribromide is added as the catalyst. Under the condition of heating or light, the reaction is initiated. Iron or iron tribromide can react with liquid bromine to form positive bromide ions, which can then electrophilic substitution of the benzene ring, introduce bromine atoms at specific positions, and finally synthesize 1-bromo-4-nitro-2 - (trifluoromethyl) benzene. This bromination process requires attention to the precise control of reaction conditions to prevent the formation of polybromination by-products.
    There are also other synthesis paths, such as compounds containing bromine and trifluoromethyl as the starting material, through a series of functional group conversion and substitution reactions, this goal can also be achieved. However, the above-mentioned synthesis route with trifluoromethylbenzene as the starting material is relatively easy to obtain, and the reaction steps are relatively clear, so it is widely used in practical synthesis.
    What are the precautions for storing and transporting 1-Bromo-4-Nitro-2- (Trifluoromethyl) Benzene?
    1-Bromo-4-nitro-2- (trifluoromethyl) benzene, when storing and transporting, it is necessary to pay attention to many key matters.
    This is a chemical substance with special properties. When storing, choose the first environment. It should be placed in a cool and dry place away from direct sunlight, which can easily cause chemical reactions, damage its quality or cause danger. And it needs to be kept away from fire and heat sources. Because of its flammability or the possibility of thermal reaction, it may cause accidents such as combustion or explosion in case of fire or high temperature.
    Furthermore, the storage place should be well ventilated. If this substance volatilizes gas, good ventilation can avoid gas accumulation and reduce harm to human body and the environment. And should be stored separately from oxidants, reducing agents, alkalis, etc. The cover is mixed with various substances due to its chemical properties, or reacts violently, causing serious consequences.
    When transporting, the packaging must be solid and reliable. Choose suitable packaging materials to ensure that there is no damage and leakage due to bumps and collisions during transportation. And transportation vehicles must also be in compliance, equipped with necessary emergency treatment equipment and protective equipment. Transportation personnel should also be familiar with the characteristics of this substance and emergency treatment methods. In case of emergencies, they can be disposed of quickly and properly.
    During loading and unloading, the operation should be gentle to avoid severe vibration and impact to prevent damage to the packaging. Transportation route planning also need to be careful, avoid densely populated areas and environmentally sensitive areas, in case of leakage, can reduce harm. In short, 1-bromo-4-nitro-2 - (trifluoromethyl) benzene storage and transportation, all links need to be careful to ensure safety.
    What are the effects of 1-Bromo-4-Nitro-2- (Trifluoromethyl) Benzene on the environment and the human body?
    1-Bromo-4-nitro-2- (trifluoromethyl) benzene is one of the organic compounds. The impact of this substance on the environment and the human body is of considerable concern.
    In terms of the environment, its chemical properties may cause many effects. If released into the atmosphere, due to certain stability, or long-term retention, it affects the balance of atmospheric components. Descending to the soil, due to its special structure, microorganisms may be difficult to decompose, or change the physical and chemical properties of the soil, such as affecting soil pH, porosity, etc., which in turn affects the growth and nutrient absorption of plant roots. Flow into water bodies, or pose a threat to aquatic organisms. Aquatic organisms may be damaged by contact with this substance. Such as interfering with the nervous system of fish, causing abnormal behavior, disordered swimming direction, decreased ability to forage and avoid natural enemies; or affecting the photosynthesis of aquatic plants, hindering their growth and reproduction, and disrupting the balance of water ecology.
    As for the human body, it enters the body through breathing, diet or skin contact. The nitro and trifluoromethyl groups of this substance may be biologically active. After entering the human body, it may interfere with normal physiological metabolism. Nitro can cause increased oxidative stress in cells, generate too many free radicals, and damage the lipids, proteins and nucleic acids of cells. Long-term exposure may increase the risk of diseases, such as cancer. Due to the damage of free radicals to DNA or gene mutation, abnormal cell proliferation is caused. And it may affect the body's immune system, causing immune cell dysfunction, reducing the body's ability to resist pathogens, and susceptible to various diseases. It may also be toxic to the nervous system, affecting the transmission of neurotransmitters, causing headaches, dizziness, memory loss and other symptoms.
    In summary, 1-bromo-4-nitro-2 - (trifluoromethyl) benzene has potential adverse effects on the environment and the human body. It should be treated with caution to prevent its excessive emission and exposure.