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1-Bromo-4-Fluoro-2-Methoxybenzene

1-Bromo-4-Fluoro-2-Methoxybenzene

Hongda Chemical

Specifications

HS Code

678664

Chemical Formula C7H6BrFO
Molecular Weight 205.02
Appearance Typically a colorless to light yellow liquid
Boiling Point Around 202 - 204 °C
Density Approximately 1.59 g/cm³
Solubility In Water Insoluble in water
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, diethyl ether, chloroform
Vapor Pressure Low vapor pressure at room temperature

As an accredited 1-Bromo-4-Fluoro-2-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - bromo - 4 - fluoro - 2 - methoxybenzene packaged in a sealed glass bottle.
Storage 1 - bromo - 4 - fluoro - 2 - methoxybenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive substances to avoid potential chemical reactions. Label the storage container clearly for easy identification.
Shipping 1 - Bromo - 4 - fluoro - 2 - methoxybenzene is shipped in well - sealed, corrosion - resistant containers. It's handled with care to prevent leakage, following strict hazardous chemical shipping regulations, ensuring safe transit.
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1-Bromo-4-Fluoro-2-Methoxybenzene 1-Bromo-4-Fluoro-2-Methoxybenzene
General Information
Historical Development
1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene is an organic compound. Its origin can be traced back to the early stages of chemical exploration in the past. At that time, chemists devoted their efforts to the wonderful method of organic synthesis.
At the beginning, for such benzene series compounds containing halogenated and methoxy groups, the synthesis methods were still immature and the yield was quite low. However, with the advent of new catalysts and the precise regulation of reaction conditions, the synthesis efficiency of 1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene has been greatly improved. In the past, complex and multi-step reactions took a long time, but now it can be obtained efficiently through a simpler way. The application of this compound in medicine, materials and other fields is also becoming more and more extensive, witnessing the development of chemistry.
Product Overview
1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene is also an organic compound. It may be a colorless to pale yellow liquid with a specific chemical structure. On the benzene ring, bromine atoms, fluorine atoms and methoxy groups are in their respective positions, giving this compound unique chemical properties.
This compound has a wide range of uses in the field of organic synthesis. It can be used as a key intermediate for the preparation of a variety of high-value-added fine chemicals. Through various chemical reactions, such as nucleophilic substitution, coupling reactions, etc., many compounds with novel structures can be derived, which have potential applications in the fields of medicine, pesticides and materials science.
The preparation method often requires a multi-step reaction, with suitable starting materials, carefully synthesized according to specific reaction conditions and steps. During the reaction process, factors such as temperature, pH and reaction time need to be precisely controlled to obtain the ideal yield and purity.
Physical & Chemical Properties
1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene is an organic compound, and its physicochemical properties are quite important. Looking at its physical properties, it is a colorless to light yellow liquid at room temperature, with a special odor. Its boiling point is about a certain range, which is determined by the intermolecular forces. As for the chemical properties, because it contains bromine, fluorine and methoxy functional groups, it is unique in activity. Bromine atoms can undergo nucleophilic substitution reactions, fluorine atoms affect the distribution of molecular electron clouds, and methoxy groups regulate the electron cloud density of benzene rings. With these properties, this compound is widely used in the field of organic synthesis, can participate in many reactions, and lays the foundation for the preparation of complex organic molecules, which is of great significance in the pharmaceutical, material and other industries.
Technical Specifications & Labeling
1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene is an important compound in organic synthesis. Its technical specifications and identification (product parameters) are the key. According to its physical properties, it should be a colorless to light yellow liquid with a specific odor. The boiling point needs to be accurately determined and should be within a certain range to meet the standard. The purity must reach an extremely high proportion, and the impurity content must be strictly controlled at an extremely low level.
In terms of identification, the product label should clearly mark its chemical name, molecular formula, molecular weight and other key information to prevent confusion. And it must be accompanied by a hazard label. Because of the chemicals involved, there are strict regulations on their storage and transportation conditions. They must be placed in a cool, dry and well-ventilated place, away from fire sources and oxidants. In this way, the product can be used safely and effectively in all aspects.
Preparation Method
1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene is an important organic compound. Its preparation method is related to the raw materials and production process, reaction steps and catalytic mechanism.
Preparation of raw materials, the corresponding precursors containing bromine, fluorine and methoxy groups can be selected. The production process is preferably based on a fine chemical synthesis path. In the first step, carefully select the appropriate reaction substrate and mix it according to a specific ratio. Second, under a suitable temperature and pressure environment, add a high-efficiency catalyst, which is the key catalytic mechanism and can significantly accelerate the reaction process. The reaction steps need to be strictly controlled. First, a specific reaction is initiated to fully interact with the substrates. Then, through separation and purification, a pure 1-Bromo-4-Fluoro-2-Methoxybenzene product is obtained. The whole process requires strict adherence to chemical operating specifications and precise regulation of parameters in each link to ensure high purity and good yield of the product.
Chemical Reactions & Modifications
1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene is an important raw material for organic synthesis. Its chemical reactions and modifications are related to many industrial production and scientific research fields.
In terms of chemical reactions, this compound can participate in nucleophilic substitution, electrophilic substitution and other reactions due to the characteristics of bromine, fluorine and methoxy groups. For example, when nucleophilic substitution occurs, bromine atoms are highly active and are easily attacked and left by nucleophiles, thereby introducing new groups and expanding the molecular structure.
In terms of modification, methoxy groups can be modified or fluorine atom positions can be changed to adjust their physicochemical properties. For example, changing the length of methoxy groups may affect the polarity of molecules, thereby affecting their solubility and reactivity.
Chemists often study the reaction and modification of this compound, hoping to obtain derivatives with better performance and wider uses, which will shine in the fields of materials science, drug research and development, and help the development of related industries and scientific progress.
Synonyms & Product Names
1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene, which also has many other names. Its aliases and trade names have specific meanings. In the field of chemical research, due to different uses, sources and characteristics, the names also vary.
or p-fluoro-methoxy bromobenzene, this name is named according to its chemical structure, from the position and category of functional groups. With a phenyl ring as the group, bromine atoms, fluorine atoms and methoxy groups are in their respective positions, so the title is convenient for chemists to quickly identify according to the structure.
It is also called 2-methoxy-4-fluorobromobenzene, which also focuses on the structure, but the order of functional groups is slightly different, but they all accurately express its chemical composition.
In commercial circulation and industrial application scenarios, each manufacturer takes a unique trade name to highlight product characteristics or adapt to market demand. But no matter how the alias or trade name changes, it all revolves around the core substance 1-Bromo-4-Fluoro-2-Methoxybenzene, which facilitates chemical research and related industry exchanges.
Safety & Operational Standards
1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene is an important chemical product. It needs to be discussed in detail in terms of its safety and operating practices.
When taking it, it is necessary to observe the rules of cleanliness. Hands should be clean, and the utensils used should also be clean and free to prevent impurities from mixing in and damaging its quality. When taking the amount, it should be accurate. According to the experimental needs, take the appropriate measuring tool, not more or less.
The method of storage should not be ignored. When placed in a cool, dry and well-ventilated place, away from fire and heat sources. This chemical is quite sensitive to temperature and humidity. Excessive temperature and excessive humidity can cause it to deteriorate. And it needs to be separated from oxidizing and reducing substances to prevent accidental chemical reactions.
When operating, protective measures are necessary. Appropriate protective clothing, such as lab clothes, gloves, etc., must be worn to protect the body. Face protection is also indispensable. Protective glasses should be worn, and if necessary, a gas mask should be prepared. Operating in a fume hood can allow volatile gas to be discharged in time to ensure the safety of the operating environment.
After the experiment is completed, the remaining 1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene must not be discarded at will. It should be properly handled, or recycled, or disposed of harmlessly according to the prescribed process to avoid polluting the environment.
There are also regulations for cleaning the utensils used. Rinse with a suitable solvent first to remove the residue, then wash with water, and dry for later use.
In short, the safety and operation specifications of 1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene are interlinked, which is related to the success or failure of the experiment, and also depends on the safety of people and the environment. There must be no slack.
Application Area
1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help create new drugs, and contribute to the treatment of diseases. Due to its unique chemical structure, it can specifically combine with molecules in organisms to exert pharmacological effects.
In materials science, it also has extraordinary performance. It can be chemically modified to introduce specific functional groups, and then prepare materials with special properties, such as optoelectronic materials, which are expected to improve its photoelectric conversion efficiency and play a role in the field of optoelectronic devices. In the field of fine chemicals, this compound is also an important raw material for the synthesis of high-value-added fine chemicals, enhancing the quality and characteristics of its products, meeting diverse industrial needs, and contributing to the development of the industry.
Research & Development
In modern times, chemistry has flourished, and the research of substances has become more and more refined. 1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene This compound, I have been studying it for a long time.
At the beginning, I wanted to obtain this substance, but there was no cure. All kinds of attempts, or the reaction was incomplete, or the impurities were overgrown. However, my heart is firm, and I have no intention of turning back.
So I read a wide range of books, sought the same way, and finally obtained a method. With a certain agent and something, according to a specific order, the temperature is controlled and combined. After repeated debugging, the reaction gradually becomes better, and the purity of the product is gradually satisfactory.
Looking at the application of this substance, it can be used in the field of medicine, or it can become a new agent to treat various diseases; in the genus of materials, it is also expected to open up new paths and create special materials.
I should make unremitting efforts to improve, hoping that this research will be a great success, which will be beneficial to the progress of chemistry, and open up new paths for future generations to see the bright new light of chemistry.
Toxicity Research
The toxicity of 1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene has been widely studied in modern times. This compound may be colorless to light yellow liquid in appearance and is useful in various fields of chemical industry.
However, its toxicity cannot be ignored. After research, if it touches human skin or sensitizes it, it will cause redness, swelling and itching. If it enters the eyes, it will damage the eyes and vision. And its volatile gas, if inhaled by humans, will damage the respiratory system, cause coughing, asthma, and even damage the function of the lungs.
It has been seen in animal experiments that long-term exposure to this substance may cause organ diseases, especially liver and kidney. Liver and kidney are important organs for human detoxification and metabolism, and damage to physical health is worrying. Therefore, when studying the toxicity of this substance, be cautious. During production and use, be prepared for comprehensive protection to prevent people and the environment from being harmed by it.
Future Prospects
Prospects of the future, in 1 - Bromo - 4 - Fluoro - 2 - Methoxybenzene, there are great expectations. This compound, in the field of chemical engineering, has great uses. Its research and development, or it can be based on new technologies, with its special properties, or it can help with special effects, and solve diseases. In the field of materials, there are also new ways, or it can be used to improve the properties of materials, such as increasing their solidification and changing their performance.
And today's chemical technology is becoming more and more exquisite. The method of synthesizing this product is not necessarily more convenient and efficient, and the quantity is also greatly increased, and the cost is reduced. In this way, its application will be more general, and it can be developed in all walks of life. Our researchers, in order to explore its depth and promote its future prosperity, hope to benefit the world, so that this compound can be used to achieve unparalleled success.
Where to Buy 1-Bromo-4-Fluoro-2-Methoxybenzene in China?
As a trusted 1-Bromo-4-Fluoro-2-Methoxybenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Bromo-4-Fluoro-2-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-bromo-4-fluoro-2-methoxybenzene?
1-% E6% BA% B4 - 4-% E6% B0% 9F - 2-%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E7%9A%84%E4%B8%BB%E8%A6%81%E7%94%A8%E9%80%94%E5%A6%82%E4%B8%8B:
This medicine has many wonderful uses in the medical way. First, it is quite effective in the disease of golden sore trauma. In case of knife and axe injury, the skin breaks the blood flow, apply an appropriate amount of this medicine to the wound, which can stop bleeding and relieve pain, help the wound heal, reduce the risk of suppuration, prevent the invasion of evil poison, and make the wound heal quickly without leaving scars.
Second, it can also be effective when a woman gives birth. When a woman is in labor, if she encounters a dangerous situation of difficult labor, her qi and blood are not smooth, and the fetus is difficult to come out, she can use it as medicine in a timely manner, which can help the flow of qi and blood, relieve contractions, enable the fetus to be delivered smoothly, keep the mother and baby safe, and reduce the risk and pain of production.
Third, it also has a good effect on the arthritis caused by wind evil entering the body. When the human body is invaded by wind, cold, and dampness, causing joint pain and unfavorable flexion and extension, this medicine can remove wind and dehumidification, clear the collaterals and relieve pain, make the qi and blood smooth, relieve joint discomfort, restore the movement of the limbs, and relieve the pain of the patient.
Fourth, in the weakness of the spleen and stomach, the disease of abnormal transportation, this medicine can If a person's spleen and stomach are damaged, loss of appetite, bloating and diarrhea, etc., taking this medicine can regulate the spleen and stomach, improve the power of transportation and transformation, restore the function of the spleen and stomach to normal, absorb nutrients, and gradually become healthier.
In short, 1-% E6% BA% B4 - 4-% E6% B0% 9F - 2-%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF%E7%9A%84%E7%94%A8%E9%80%94 is widely used, and can play an important role in many aspects such as saving injuries, midwifery, removing evil spirits, and regulating the spleen and stomach. It is a common medicine for doctors to treat diseases.
What are the physical properties of 1-bromo-4-fluoro-2-methoxybenzene?
The physical properties of 1-% ether-4-alkane-2-aminoaniline are particularly important, which is related to the use and characteristics of this substance. This substance is mostly solid at room temperature, with a white color and a fine powder. The quality is uniform and delicate.
Its melting point is quite clear, about [X] degrees Celsius. This property is very useful in identifying and separating this substance. When heated to this temperature, this substance gradually melts from solid to liquid, and the process is smooth and orderly.
Furthermore, its solubility is also characteristic. In common organic solvents such as ethanol and ether, it has a certain solubility. In ethanol, after moderate stirring, it can be partially dissolved, and the solution is slightly clarified, because there is a suitable interaction between molecules and ethanol molecules. However, in water, its solubility is very small, insoluble and floating on the water surface. Because of its molecular structure, its affinity with water molecules is weak.
The density of this substance is slightly higher than that of water, and when it is put into water, it sinks to the bottom. This density characteristic needs to be considered in many practical application scenarios, such as the separation and storage of mixed systems.
Its smell is weak, and when you get close to it, you can feel a light and specific smell. It is not pungent and smelly, and has little impact on the environment and operators.
In addition, the stability of 1-% ether-4-alkane-2-aminoaniline is also worth mentioning. It can maintain its own structure and properties for a long time under normal temperature and pressure without the action of special chemical reagents, which provides a basic guarantee for its wide application in various fields.
What are the chemical properties of 1-bromo-4-fluoro-2-methoxybenzene?
The chemical properties of 1-% cyanogen-4-alkynyl-2-aminocarbonyl benzene are particularly important, which is related to the mechanism of many chemical reactions and substance transformation. In this compound, cyanyl (-CN) has strong electron-absorbing properties, which can reduce the electron cloud density of the benzene ring and affect its electrophilic substitution activity. The presence of cyanyl groups decreases the electron cloud density of the adjacent and para-sites of the benzene ring, especially the meta-potential is relatively high, so the electrophilic substitution reaction is prone to occur in the meta-site.
alkynyl groups (- C ≡ C -) give the compound unique chemical activity. The alkynyl groups are unsaturated and can undergo addition reactions, such as with hydrogen, halogens, hydrogen halides and other electrophilic reagents. Because the alkynyl group is conjugated with the benzene ring, it can disperse the electron cloud of the system, enhance the molecular stability, and affect the reactivity of the benzene ring and cyanyl group at the same time.
And 2-aminocarbonyl (-CONH ³) is also a key functional group. In aminocarbonyl groups, nitrogen atoms have lone pair electrons, which can participate in coordination reactions to form complexes. Carbonyl groups (C = O) are polar and can undergo nucleophilic addition reactions, such as reactions with nucleophiles such as alcohols and amines. In addition, aminocarbonyl groups can interact with other molecules through hydrogen bonds, affecting the physical properties of compounds, such as melting point, boiling point, and solubility.
In chemical reactions, the functional groups of 1-% cyanogen-4-yne-2-aminocarbonyl benzene interact with each other, presenting complex reactivity. The electronic and spatial effects between the functional groups restrict each other, determining the reaction path and product selectivity of the compound under different reaction conditions. Chemists need to carefully regulate the reaction conditions, such as temperature, solvent, catalyst, etc., in order to achieve the target reaction and obtain the desired product, which is of great significance in the fields of organic synthesis and pharmaceutical chemistry.
What are the preparation methods of 1-bromo-4-fluoro-2-methoxybenzene?
The method of 1-% -4-2-aminobenzoic acid generally has the following characteristics:
First, benzoic acid is used as the starting material, nitrification, acetylation, etc. It is obtained in multiple steps. First, the benzoic acid is combined with nitric acid and sulfuric acid, and nitrification is carried out to obtain nitrobenzoic acid. This step requires control of the degree of reaction, in order to prevent the degree of nitrification. And with the raw materials such as powder, sulfuric acid or sulfide, nitrobenzoic acid is original to aminobenzoic acid. However, the cost of powder and acid method is low, and a large amount of sludge is generated, which is unfavorable to the environment. The sulfide method is relatively low, but the cost is slightly higher. The most expensive, the obtained aminobenzoic acid is suitable for aminobenzoic acid, which can be obtained.
Second, the phthalic acid anhydride is used as the raw material. The phthalic acid anhydride is first aminated and reacted to form a phthalamide. In this step, ammonia water or a phase amide compound can be used. Next, the phthalamide is degraded and reacted by Hoffman under the high-performance component. This method is a step in the process of phase improvement, and the efficiency can also be improved. However, the Hoffman degradation reaction requires careful operation, because it involves toxic raw materials such as bromine or chlorine, and the reaction is harsh.
Third, the direct amination method is used. In the presence of a specific catalyst, the benzoic acid is directly reacted to ammonia and synthesized into aminobenzoic acid in one step. This method has a promising future for industrial use. However, the catalytic requirements are very high, and the reverse parts also need to be precisely controlled, such as high temperature, high temperature, etc., whether to obtain the ideal efficiency.
The above methods have their own advantages and disadvantages. In the production process, it is necessary to consider the availability of raw materials, cost considerations, environmental requirements and other factors to consider the most appropriate way.
What should be paid attention to when storing and transporting 1-bromo-4-fluoro-2-methoxybenzene?
When storing and transporting 1-mercury-4-arsenic-2-aminobenzoic acid, pay attention to many key points.
Mercury is a highly toxic metal element that is liquid at room temperature and volatile. When storing mercury, it is necessary to choose a well-sealed container to prevent the evaporation of mercury from escaping, causing pollution to the environment and human harm. The container material should be glass or metal, because it has good tolerance to mercury. And mercury should be stored in a cool and ventilated place, protected from heat and light, to prevent mercury volatilization from increasing due to rising temperature. When transporting mercury, be sure to ensure that the packaging is stable to prevent mercury leakage due to damage to the container. In case of accidental leakage, it should be covered with sulfur powder as soon as possible, because mercury and sulfur can quickly combine to form mercury sulfide, reducing toxicity.
Arsenic is also a toxic element and is commonly found in various compounds. Store arsenic compounds in a dry and cool place to avoid contact with acids and alkalis. Because some arsenic compounds are prone to react with acids and alkalis, or cause toxic gases to escape. Packaging must be tight and marked with a clear toxic label. During transportation, prevent package damage. If there is any leakage, it should be disposed of according to specific hazardous waste treatment procedures to avoid arsenic diffusion and pollution of the environment.
2-Aminobenzoic acid is an organic compound. When storing, attention should be paid to moisture prevention and oxidation prevention. It should be placed in a dry and dark container, and an appropriate amount of antioxidants can be added to delay its oxidation process. During transportation, avoid high temperature and severe vibration, because high temperature or vibration may cause chemical reactions and affect its quality. At the same time, relevant chemical transportation regulations must be followed to ensure transportation safety.
All three are dangerous. During storage and transportation, operators must be familiar with their characteristics, operate in strict accordance with safety procedures, and strengthen protective measures to ensure the safety of personnel and the environment from pollution.