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1-Bromo-4-Fluoro-2,3-Dimethylbenzene

1-Bromo-4-Fluoro-2,3-Dimethylbenzene

Hongda Chemical

    Specifications

    HS Code

    826255

    Chemical Formula C8H8BrF
    Molecular Weight 203.05
    Appearance Colorless to light yellow liquid
    Boiling Point 200 - 202 °C
    Density 1.429 g/mL at 25 °C
    Flash Point 84 °C
    Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
    Refractive Index 1.528 - 1.530

    As an accredited 1-Bromo-4-Fluoro-2,3-Dimethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 1 - bromo - 4 - fluoro - 2,3 - dimethylbenzene in a sealed glass bottle.
    Storage 1 - Bromo - 4 - fluoro - 2,3 - dimethylbenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass. Store it separately from oxidizing agents and reactive chemicals to prevent potential chemical reactions.
    Shipping 1 - bromo - 4 - fluoro - 2,3 - dimethylbenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, with proper labeling indicating its nature to ensure safe transportation.
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    1-Bromo-4-Fluoro-2,3-Dimethylbenzene 1-Bromo-4-Fluoro-2,3-Dimethylbenzene
    General Information
    Historical Development
    1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene is an organic compound. Looking back at its historical development, back in the past, when organic chemistry was first emerging, chemists focused on basic research and limited exploration of benzene derivatives. At that time, the conditions were simple and analytical technology was lacking.
    With the gradual progress of science and technology, instrumental analysis methods emerged, and spectroscopy and mass spectrometry technologies helped people to accurately analyze its structure. In the past, the synthesis of this compound was complicated and the yield was low.
    However, the technology did not stop, new reaction mechanisms were discovered, and catalysts were improved. After repeated research, chemists optimized the synthesis path to make its preparation more efficient and economical. Today, 1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene is widely used in materials science, drug development and other fields, and its historical development has witnessed the progress of chemistry.
    Product Overview
    1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene is an important organic compound. Its appearance is colorless to light yellow liquid, with a special odor. In the structure of this compound, there are bromine, fluorine and dimethyl groups attached to the benzene ring, and the unique chemical structure gives it specific chemical properties.
    In the field of organic synthesis, 1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene is often used as a key intermediate. Due to the activity of bromine and fluorine atoms, it can participate in many nucleophilic substitution reactions, introduce other functional groups, and build complex organic molecules. The presence of methyl groups affects the electron cloud density of the benzene ring, further regulating its reactivity and selectivity.
    In industrial production, this compound can be obtained by carefully controlling the reaction conditions through specific chemical reaction paths. However, the production process needs to pay attention to safety and environmental protection, because some raw materials may be dangerous. Overall, 1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene is of great value in organic synthesis and related fields, and is of great significance to promote the development of chemical science and industrial progress.
    Physical & Chemical Properties
    1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene is also an organic compound. Its physical and chemical properties can be investigated quite well. Looking at its shape, it is liquid at room temperature and has a special odor. In terms of its physical properties, the melting boiling point is related to the intermolecular force. Because of the presence of halogen atoms and methyl groups in the molecular structure, it affects the attractive force between molecules, and the melting boiling point has a specific value. Its solubility may be good in organic solvents such as ethanol and ether, but it is insoluble in water, which is caused by the difference in molecular polarity and water molecular polarity. In terms of its chemistry, halogen atoms are active and can initiate many reactions. Bromine atoms are easily replaced by nucleophilic reagents, and nucleophilic substitution reactions occur; methyl groups on benzene rings can be oxidized, showing unique chemical reactivity. Therefore, the physicochemical properties of 1-Bromo-4-Fluoro-2,3-Dimethylbenzene are of great value for research and application in organic synthesis and other fields.
    Technical Specifications & Labeling
    1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene is an important chemical substance. Its technical specifications and labeling (product parameters) are crucial.
    When it comes to technical specifications, this compound needs to meet specific purity requirements, and the impurity content must be strictly controlled to ensure that its chemical properties are stable and meet application standards. Its appearance should show a specific color and shape, which is a key identification point.
    In terms of labeling, the name and chemical formula should be clearly marked so that the user can see at a glance. Product parameters should also be detailed, such as molecular weight, density and other physical parameters, to provide an accurate basis for subsequent use. Only in this way can 1-Bromo-4-Fluoro-2,3-Dimethylbenzene be used accurately in scientific research and industrial applications.
    Preparation Method
    1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene is an organic compound. The preparation method, raw materials and production process are the key.
    First take an appropriate amount of 2,3 - dimethylphenol, this is one of the raw materials. Using hydrofluoric acid as a fluorination reagent, in an environment with low temperature and catalyst, slowly add it to undergo fluorination reaction, and 4 - fluoro - 2,3 - dimethylphenol can be obtained. The reaction conditions need to be precisely controlled, and the temperature and reagent ratio will affect the purity of the product.
    Then, a brominating agent, such as liquid bromine, reacts with 4 - fluoro - 2,3 - dimethylphenol under specific solvents and catalysts. This bromination step should also pay attention to the reaction process and adjust the conditions in time. Through this series of reaction steps, 1-Bromo-4-Fluoro-2,3-Dimethylbenzene can be obtained according to the established reaction mechanism. However, after each step of reaction, it needs to be carefully separated and purified to ensure the purity of the product.
    Chemical Reactions & Modifications
    Today there is a substance called 1-Bromo-4-Fluoro-2,3-Dimethylbenzene. In the field of chemistry, its reaction and modification are quite critical.
    To observe its reaction, chemists need to investigate its structure and characteristics in detail. The bromine, fluorine and dimethyl of this substance each have their own properties, which affect the reaction path. Such as nucleophilic substitution, bromine atoms are active and easy to be attacked by nucleophiles, leading to changes in the reaction.
    As for modification, it is designed to increase its properties and is suitable for more uses. It can be chemically modified to adjust its physical and chemical properties. Or change its solubility or increase its stability.
    Chemists should use scientific methods to study the reaction and modification of this substance for the advancement of chemistry, the prosperity of industry, and the well-being of it. In the microscopic realm, explore its mysteries, turn decay into magic, and become useful materials for the benefit of future generations.
    Synonyms & Product Names
    Today there is a thing called 1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene. Its same trade name can be investigated. This compound is commonly used in chemical domains. If it is the same, it means that this thing is different, but the references are all the same. The trade name is related to commerce and use, and different companies may have different names.
    If you want to make it the same, you can also make it into an ancient book or a research text. Or there is another name for it, and there are those who call it according to the nomenclature. As for the trade name, it is not circulated in the market, and it is publicized by the company. Different brands, or promotion, give their special names, hoping to attract people's attention and promote the increase of sales. Therefore, it is important to explore this object together with the product name, in terms of research and business activities.
    Safety & Operational Standards
    1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene is a chemical substance, which is related to its safety and operating practices and should not be ignored.
    This substance is dangerous to a certain extent. When operating, the first thing to do is to ensure that the environment is well ventilated. There should be perfect ventilation equipment indoors to prevent the accumulation of harmful gases and endanger personal safety. If operating in a confined space, the toxic gas will not dissipate, and there is a risk of poisoning.
    Operators must wear appropriate protective equipment. Protective clothing should be able to resist its possible erosion, and gloves should have good chemical resistance to prevent skin contact. At the same time, goggles are also indispensable to protect the eyes from the damage of its splashing. If the skin is inadvertently touched, it should be rinsed with plenty of water immediately. If there is any discomfort, seek medical attention immediately.
    For storage, it should be placed in a cool, dry and ventilated place. Keep away from fire and heat sources to prevent fire or explosion. When storing different chemicals, pay attention to their reactions with each other, and must not be mixed at will to avoid dangerous chemical reactions.
    During operation, the instruments used must be clean, dry and intact. Careful inspection should be made before use to ensure that it is correct. Precise control of reaction conditions, such as temperature, pressure, reaction time, etc., is also essential. A slight poor pool not only affects the quality of the product, but also may cause safety accidents.
    When using this material, follow the specified operating procedures, the dosage is accurate, waste is avoided, and danger is prevented due to excessive use. After the experiment is completed, properly dispose of the remaining materials and waste, do not discard them at will, and dispose of them in accordance with relevant regulations to protect the environment.
    In this way, strict adherence to safety and operating standards can ensure the safety of personnel and the smooth progress of the experiment during the research and production of 1-Bromo-4-Fluoro-2,3-Dimethylbenzene.
    Application Area
    1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene is an organic compound with a wide range of application fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create drugs with specific effects to treat various diseases. In the field of materials science, through specific reactions, it can be integrated into polymer materials to give materials unique properties such as enhanced stability or improved optical properties. In the fine chemical industry, this compound can be used to synthesize high-end fragrances or special dyes to add a unique aroma or color to products. On the stage of organic synthetic chemistry, it is like a cornerstone. With its unique structure and activity, it paves the way for innovation and development in many fields, and promotes related industries to continuously reach new heights.
    Research & Development
    In the field of chemical industry, I have been researching this 1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene for a long time. This compound has a unique structure and performance. At the beginning, I explored the method of its synthesis, after many twists and turns. The choice of raw materials and the degree of mixing need to be carefully considered.
    Begin with the conventional method, the effect is not good, and the yield is quite low. Then study the classics, learn from the strengths of various families, and improve the process. In the reaction conditions, such as temperature, pressure, and catalyst dosage, repeated debugging. Gradually obtained, the yield also increased steadily.
    And explore its characteristics. In different solvents, the solubility and stability have different performances. This compound has great potential in the field of organic synthesis and can be used as an intermediate for many fine chemicals. We hope to use this as a basis to expand the application path, promote the progress of the industry, and contribute to the development of the chemical industry, so that its potential can be fully developed and used by the industry.
    Toxicity Research
    The study of a chemical is related to the toxicity of 1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene, and is now being investigated in detail.
    In the past, the toxicity of various substances was studied with caution. The 1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene has a unique molecular structure and contains bromine, fluorine and dimethylbenzene groups.
    To investigate its toxicity, first observe the effect of its contact with organisms. Or observe the changes in cells and tissues after its entry into the body. For example, observe whether it hinders the growth and metabolism of cells and whether it causes cytopathies. It also examines what abnormalities it has on the physiological functions and behavior of animals in animal experiments.
    And consider the impact of its diffusion and migration in the environment on the surrounding biological communities. Whether it causes ecological imbalance or causes biological variation. After this detailed investigation, it is hoped that the toxicity of 1-Bromo-4-Fluoro-2,3-Dimethylbenzene can be determined for future protection and treatment.
    Future Prospects
    Prospects of the future, in 1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene This product is of great importance to our researchers. The material has the characteristics of transformation, and the strength of the product.
    Not yet, or can be used in exquisite synthesis. With its basis, it is a multi-functional and effective molecule, which can be used in the field of development, or can assist in the research of special effects and solve the pain of disease. In the field of materials, it is also expected to give birth to new materials, such as better performance, resistance, etc.
    Furthermore, its synthesis method also needs to be refined. Hoping to achieve it in a more colorful and efficient way, reduce energy consumption, reduce pollution, and be sustainable. In this way, 1 - Bromo - 4 - Fluoro - 2,3 - Dimethylbenzene will definitely be able to expand its color and promote the progress of the field, for the benefit of the world.
    Where to Buy 1-Bromo-4-Fluoro-2,3-Dimethylbenzene in China?
    As a trusted 1-Bromo-4-Fluoro-2,3-Dimethylbenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1-Bromo-4-Fluoro-2,3-Dimethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 1-Bromo-4-Fluoro-2,3-Dimethylbenzene?
    1-Bromo-4-fluoro-2,3-dimethylbenzene is also an organic compound. It has a wide range of uses and is used in various fields of chemical industry.
    First, it is often a key intermediate in the process of organic synthesis. It can be converted into other types of organic compounds through various reactions. If it interacts with nucleophiles, different substitutions are obtained. In nucleophilic substitution reactions, bromine or fluorine atoms can be replaced by other functional groups, such as hydroxyl and amino groups, to build more complex organic molecules to meet the needs of medicine, pesticides, etc.
    Second, it also has important functions in the field of materials science. The polymer system can be introduced into the polymer system through specific reactions to impart different properties to the material. For example, to improve the thermal stability and chemical stability of the material, or to adjust its optical properties. With this, polymer materials suitable for special scenarios can be prepared, such as high-performance engineering plastics, optoelectronic device materials, etc.
    Third, in the field of medicinal chemistry, this compound can be the building block of lead compounds. By modifying its structure, explore the biological activity of different derivatives, or hope to discover new substances with pharmacological activity, and open up a path for the development of new drugs.
    Fourth, in the field of pesticide chemistry, it is used as a starting material to synthesize derivatives through a series of reactions, or has biological activities such as insecticidal, bactericidal, and herbicidal, which can provide the possibility for the creation of new pesticides.
    In short, 1-bromo-4-fluoro-2,3-dimethylphenyl has a unique structure and shows broad application prospects in the fields of organic synthesis, materials science, medicine, and pesticides, providing a key foundation for the development of many fields.
    What are the physical properties of 1-Bromo-4-Fluoro-2,3-Dimethylbenzene
    1-Bromo-4-fluoro-2,3-dimethylbenzene is one of the organic compounds. Its physical properties are quite impressive, as detailed below:
    First words appearance and properties, under normal temperature and pressure, this material is often colorless to light yellow liquid, pure clear and transparent, looking quite shiny. This form is convenient for it to mix and contact with other substances in many chemical reaction systems, thus participating in various chemical changes.
    Second, its boiling point is within a specific range due to the influence of intermolecular forces. Specifically, around a certain temperature value, this boiling point value is of great significance for the separation and purification of the substance. In experimental operations such as distillation or industrial production processes, controlling this boiling point temperature can effectively separate it from the mixture and obtain a pure product.
    Furthermore, the melting point is also one of its important physical properties. Its melting point temperature is relatively fixed and plays a key role in the mutual transformation of solid and liquid states. Knowing the melting point is an indispensable basis for identifying the substance and determining its purity. With higher purity, the melting point often approaches the theoretical value; if it contains impurities, the melting point may be deviated.
    In terms of density, 1-bromo-4-fluoro-2,3-dimethylbenzene has a certain density value. This density characteristic determines its floating or sinking state when mixed with other liquids, and is an important consideration in the phase separation operation of chemical production and the study of its distribution in different media.
    Solubility is also a property that cannot be ignored. The substance exhibits good solubility in organic solvents such as ethanol and ether, and can be mutually soluble with these organic solvents in a certain proportion. However, its solubility in water is poor. This difference is due to the difference in molecular structure and the force between water molecules. This solubility characteristic provides the basis for its application in organic synthesis, extraction and other fields.
    In addition, the compound has a certain volatility. Although the volatility is not extremely strong, some molecules will escape into the gas phase in an open system or in a slightly higher temperature environment. This volatility requires its storage conditions and needs to be sealed to prevent material loss and environmental impact.
    In summary, the physical properties of 1-bromo-4-fluoro-2,3-dimethyl benzene are interrelated and have their own uses, and are of great value in chemical research, industrial production and other fields.
    Is 1-Bromo-4-Fluoro-2,3-Dimethylbenzene chemically stable?
    The stability of the chemical properties of 1-bromo-4-fluoro-2,3-dimethylbenzene depends on many factors. This compound contains halogen elements such as bromine and fluorine, and methyl is attached to the benzene ring.
    Looking at its halogen atoms, the activities of bromine and fluorine are different. Fluorine atoms are extremely electronegative, which has a significant impact on the distribution of electron clouds on the benzene ring. The electron cloud density of the benzene ring decreases, making it difficult for electrophilic substitution reactions to occur, which increases its stability to a certain extent. However, although the electronegativity of bromine atoms is not weak, its atomic radius is large, and the C-Br bond energy is relatively small. Under certain conditions, in case of nucleophiles, the C-Br bond is easily broken, which leads to chemical reactions and reduces its stability.
    Again, methyl, which is a power supply radical, can increase the density of adjacent and para-electron clouds of the benzene ring, which is favorable for electrophilic substitution reactions. However, the existence of multiple methyl groups may increase the steric resistance. When the steric resistance is large, it is difficult for the reactants to approach the active check point of the benzene ring, or some reactions are difficult to occur, which indirectly increases its stability.
    Under normal conditions, 1-bromo-4-fluoro-2,3-dimethylbenzene is relatively stable without external interference. In case of special conditions such as high temperature, strong acid and alkali, strong oxidizing agent or reducing agent, its chemical properties may become active and lead to chemical reactions. Therefore, its stability depends on the specific environment and reaction conditions, and cannot be generalized.
    What are the synthesis methods of 1-Bromo-4-Fluoro-2,3-Dimethylbenzene?
    The synthesis of 1-bromo-4-fluoro-2,3-dimethylbenzene is an important topic in the field of organic synthesis. In the past, there were several common paths to synthesize this compound.
    One is to use 2,3-dimethylphenol as the starting material. Shilling 2,3-dimethylphenol interacts with halogenating reagents to introduce bromine atoms or fluorine atoms. If reacted with brominating reagents, under appropriate conditions, bromine atoms will selectively replace hydrogen atoms at specific positions on the benzene ring to form bromine-containing derivatives. After that, fluorine atoms are introduced through suitable fluorination reactions. In this process, the reaction conditions, such as temperature, solvent, catalyst, etc., need to be finely regulated to ensure that the reaction proceeds in the desired direction and improve the yield and purity of the target product.
    Second, o-xylene is used as the starting material. First, the halogenation reaction of o-xylene is carried out, and one of the bromine atoms or fluorine atoms is introduced. For example, using specific halogenation conditions, the bromine atom is connected to a specific position in the benzene ring. Then, through the subsequent reaction, another halogen atom is introduced, and the methyl group on the benzene ring is appropriately modified to finally achieve the synthesis of 1-bromo-4-fluoro-2,3-dimethylbenzene. This path requires clever design of the reaction steps, considering the sequence of each step and the mutual influence of each step, in order to avoid unnecessary side reactions
    In addition, other compounds containing benzene rings can also be considered as starting materials, and the structure of the target molecule can be gradually constructed through a series of organic reactions such as substitution, addition, and elimination. However, no matter what kind of synthesis method is used, it is necessary to have a deep understanding of the organic reaction mechanism, carefully optimize the reaction conditions, and strictly control the reaction process to obtain high-purity 1-bromo-4-fluoro-2,3-dimethylbenzene to meet the needs of different fields for this compound.
    What to pay attention to when storing and transporting 1-Bromo-4-Fluoro-2,3-Dimethylbenzene
    1-Bromo-4-fluoro-2,3-dimethylbenzene-based organic compounds. During storage and transportation, careful attention should be paid to many key matters to ensure their safety.
    When storing, the first choice of environment. This compound must be placed in a cool and well-ventilated place, away from fire and heat sources. Because of its flammability, if exposed to heat or open flame, or risk of fire. The warehouse temperature should be controlled within a specific range to prevent its properties from changing due to excessive temperature.
    Furthermore, the storage container should be kept intact and tightly sealed. 1-Bromo-4-fluoro-2,3-dimethylbenzene is volatile. If the container is not well sealed, it will evaporate and escape, or cause air pollution, and the material will be lost. It is also crucial to choose a container of suitable materials, such as corrosion-resistant materials. Due to the chemical reaction of the compound or with certain materials, the container will be damaged and the leakage accident will be caused.
    Also pay attention to its isolation from other substances. Do not co-store with oxidizing agents, acids, alkalis, etc., because it encounters these substances or causes violent chemical reactions, which poses a serious safety hazard.
    When transporting, the packaging must be solid and reliable. In accordance with relevant regulations, appropriate packaging materials and methods are used to ensure that the packaging is not damaged due to bumps and collisions during transportation. Transportation vehicles must also meet safety requirements and be equipped with necessary fire fighting equipment and leakage emergency treatment equipment.
    Transportation personnel should also be professionally trained to be familiar with the characteristics of the compound and emergency treatment methods. During transportation, drive cautiously to avoid high temperature periods and densely populated areas. If a leak unfortunately occurs, it should be dealt with immediately according to the emergency plan, evacuate the surrounding people, seal the scene, and prevent the spread of pollution.