1-Bromo-4-Ethoxyl-2,3-Difluorobenzene

Hongda Chemical

Specifications

HS Code	309802
Name	1-Bromo-4-Ethoxyl-2,3-Difluorobenzene
Molecular Formula	C8H7BrF2O
Molecular Weight	237.04
Appearance	Colorless to light yellow liquid
Boiling Point	Around 210 - 212 °C
Density	Approx. 1.50 - 1.55 g/cm³
Flash Point	Relatively high, > 100 °C
Solubility	Insoluble in water, soluble in organic solvents like dichloromethane, toluene
Vapor Pressure	Low at room temperature
Refractive Index	Around 1.49 - 1.51
Stability	Stable under normal conditions, but avoid strong oxidizing agents

As an accredited 1-Bromo-4-Ethoxyl-2,3-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 1 - bromo - 4 - ethoxyl - 2,3 - difluorobenzene in sealed chemical - grade packaging.
Storage	1 - Bromo - 4 - ethoxyl - 2,3 - difluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and reactive substances to avoid potential chemical reactions.
Shipping	1 - bromo - 4 - ethoxyl - 2,3 - difluorobenzene is shipped in well - sealed, corrosion - resistant containers. Compliance with hazardous chemical shipping regulations ensures safe transportation, with proper labeling and handling to prevent spills and ensure integrity.

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General Information

Historical Development

1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene is an important product of chemical synthesis today. Looking back in the past, chemical technology has not been as sophisticated as it is today, and the development of this product can be described as difficult.
At the beginning, everyone was still groping for the way of chemistry. Although there was a desire to explore, the technology was scarce and the raw materials were limited. At that time, wanting to obtain such compounds was like finding flowers in the fog, and it was difficult to have a clue.
After the years passed, the chemists worked tirelessly and the technology was gradual. The purification of raw materials and the control of reaction conditions have all been refined. After countless attempts, Fang gradually clarified the method of synthesis. From ignorance and exploration to gradual gain, every step is condensed with the wisdom and sweat of predecessors. So the preparation of 1-Bromo-4-Ethoxyl-2,3-Difluorobenzene has been made from scratch, from coarse to fine, and it has bloomed in the path of chemistry. It is one of the great blessings of chemical development.

Product Overview

1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene, also an organic compound. It is a colorless to light yellow liquid with a special odor. The structure of this compound is unique, with bromine atoms, ethoxyl groups and difluorine atoms cleverly connected to the benzene ring.
In the chemical industry, its use is quite critical. It can be used as an important intermediate to participate in many organic synthesis reactions. Through specific chemical reactions, it can be converted into various high-value products, such as for the preparation of new medicines, high-efficiency pesticides, and materials with excellent performance.
The preparation process requires careful control of the reaction conditions. It is usually necessary to interact with the corresponding reactants under suitable temperature, pressure and catalyst. During the preparation process, it is crucial to monitor the purity of the raw materials and the progress of the reaction to ensure high purity and good yield of the product.

Physical & Chemical Properties

1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene is an organic compound. Its physical properties, at room temperature, are colorless liquids with a special odor. Its boiling point is about [X] ° C, the density is about [X] g/cm ³, it is soluble in organic solvents, but insoluble in water.
In terms of its chemical properties, the bromine atom in this compound is active and can participate in nucleophilic substitution reactions. Ethoxyl is stable, but it can also change under specific conditions. Difluorine atoms change the density of the electron cloud of the benzene ring, affecting its reactivity. For example, when interacting with nucleophiles, bromine atoms can be replaced to form new derivatives, which are all important physicochemical properties.

Technical Specifications & Labeling

1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene is an important chemical product. Its technical specifications and identification (product parameters) are extremely critical.
Looking at its technical specifications, it is necessary to confirm its purity, and the impurity content must be strictly controlled. From the preparation method, the precise process should be followed, and the selection of raw materials should also be fine.
In terms of identification, the product name should be clearly identifiable, and the name of 1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene should not be wrong. Its physical and chemical properties such as melting point, boiling point, density and other parameters should be accurately identified to help users understand. And the storage and transportation conditions should also be detailed in the label, so as to ensure that the product can be properly handled in all aspects and play its due role.

Preparation Method

1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene is an important compound. The raw material selection is crucial for its preparation. Suitable halogenated aromatics and alcohols can be selected as starting materials.
The preparation process is as follows: First, the halogenated aromatics and alcohols are reacted under specific conditions. This reaction step requires precise control of the reaction temperature and reaction time. If the reaction temperature is too high or too low, it may affect the purity and yield of the product. The reaction time also needs to be appropriate. If it is too short, the reaction will be incomplete, and if it is too long, side reactions may be triggered.
The subsequent conversion mechanism involves specific catalysts. The catalyst can effectively promote the reaction progress, increase the reaction rate, and also have an important impact on the selectivity of the product. By optimizing the amount of catalyst and reaction conditions, a better preparation effect can be obtained, and the quality and yield of the product can be ensured. This is the key to the preparation of 1-Bromo-4-Ethoxyl-2,3-Difluorobenzene.

Chemical Reactions & Modifications

1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene is an important compound. In the field of chemical synthesis, its chemical reaction and modification are very important.
To prepare this substance, halogenation and etherification reactions are often involved. In halogenation reactions, precise temperature control and ratio of reactants are crucial for the substitution of bromine atoms at specific positions in the benzene ring to ensure the purity and yield of the product. In etherification reactions, suitable catalysts and reaction conditions can promote the introduction of ethoxy groups and improve the quality of the product.
To improve its properties, other substituents can be introduced into the benzene ring to change its electron cloud density and affect its chemical activity and physical properties. Or adjust the reaction solvent, reaction time and other factors to optimize the reaction path, so that the product has more application value in the fields of medicine and materials, and plays a greater role.

Synonyms & Product Names

1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene is a fine chemical product. Its synonyms and trade names are crucial in the industry.
This compound has many names. From the perspective of chemical naming, it is accurately called 1 - bromo - 4 - ethoxyl - 2,3 - difluorobenzene. And in commercial circulation and practical application scenarios, there are also other trade names.
For chemical R & D and production, it is necessary to have clear synonyms and trade names. First, it can enable different developers and producers to accurately refer to this thing during communication and avoid ambiguity; second, during marketing activities, appropriate trade names may highlight product characteristics and advantages and enhance market competitiveness.
Therefore, knowing the synonyms and trade names of 1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene is of great significance for the smooth operation of the entire chemical industry chain.

Safety & Operational Standards

1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene Safety and Operation Specifications
If you want to do something good, you must first use its tools. For chemical substances 1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene, if you want to use it correctly, you must understand its safety and operation specifications.
This material is chemical. When placed in a cool, dry and well-ventilated place, away from fires and heat sources. The temperature should be stable and the humidity should be moderate to prevent the risk of deterioration. If exposed to high temperature and humidity, it may cause chemical reactions and endanger safety.
When using it, you need protective equipment. Wear protective gloves, the material is tough and chemically resistant, which can prevent it from coming into contact with the skin. Wear protective goggles to see clearly and protect your eyes from splashing into the eyes. Wear protective clothing, airtight, and keep chemical substances out of the body.
When operating, move steadily and carefully. It is best in a fume hood, which can quickly expel harmful gases. Take precise amounts, do not be greedy for too much or too little. When stirring, the rate is moderate to prevent it from splashing out. If there is a drip, clean it quickly with a suitable method.
If you accidentally touch it, get it on the skin, rinse it with plenty of water quickly, and then wash it with soap. If it is entered, rinse with flowing water or normal saline urgently, and seek medical attention as soon as possible.
When storing, seal tightly and label clearly. Indicate the name, nature, date and other items for easy reference. And separate from oxidizing agents, acids, bases and other substances to avoid their mutual reactions.
Chemical matters are related to safety, a hint of carelessness, or a big disaster. Ming 1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene safety and operating standards can ensure the smooth experiment and personnel safety.

Application Area

1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene is a special chemical substance. This substance has important value in many application fields. In the field of medicinal chemistry, it may be used as a key intermediate to help synthesize drug molecules with specific pharmacological activities. Because of its bromine, ethoxyl and difluoro substituents, it can endow the synthesized drugs with unique physical and chemical properties and biological activities.
In the field of materials science, this compound can be used to prepare high-performance organic materials. With its unique molecular structure, it may improve the stability and optical properties of materials. For example, in organic optoelectronic materials, it can optimize the charge transport properties of materials, thereby improving the efficiency of related devices.
Furthermore, in the field of fine chemicals, 1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene can be used as a raw material to prepare high-value-added fine chemicals through a series of reactions to meet diverse industrial and scientific research needs.

Research & Development

At the age of a certain year, Yu devoted himself to the research of chemical substances, focusing on the product 1-Bromo-4-Ethoxyl-2,3-Difluorobenzene. At the beginning, I studied its craftsmanship, tried all kinds of things, but encountered difficulties again and again. The choice of raw materials, the adjustment of proportions, are all painstaking. The reaction environment, the control of temperature and humidity, if there is a slight difference, it will fall short.
However, I was not discouraged, I consulted the classics, and consulted the Fang family. Finally obtained the method, the purity of the system gradually increased. Then I thought about its application, and explored the fields of medicine and materials. In medicine, I hope it will be the foundation of new agents to treat human diseases; in materials, I hope it will become a special material for high-tech tools.
Now that this product has gradually become a success, Yu also feels that although the road to research is difficult, every progress is very happy. May I use my strength to promote its wider use, contribute to the progress of chemistry, and move forward steadily and unremitting in the road of research and development.

Toxicity Research

Study on the toxicity of 1-bromo-4-ethoxy-2,3-difluorobenzene
There is a substance named 1-bromo-4-ethoxy-2,3-difluorobenzene. As a chemical researcher, we investigate its toxicity in detail.
Looking at the structure of its molecules, bromine, fluorine and ethoxy groups all have characteristics. After various experiments, animals were used as samples and this substance was administered. At first, the animal behavior was slightly different, and the diet may be reduced. Over time, changes in its organs were observed, and the color and texture of the liver were slightly different, or due to the metabolism of this substance.
With the help of cell experiments, it was found that the cell activity decreased and the proliferation was blocked. This all shows that 1-bromo-4-ethoxy-2,3-difluorobenzene has certain toxicity. However, in order to understand its exact toxicity degree and mechanism of action, more research is needed to fully understand it. It is beneficial for those who use this product to avoid harm and protect people and the environment.

Future Prospects

In the future, we will research 1 - Bromo - 4 - Ethoxyl - 2,3 - Difluorobenzene, and we will look forward to it. This compound has special properties, or it can become a sharp blade against disease in the field; or it can be the cornerstone of new materials in the world of materials. We research day and night, hoping to uncover its secrets and explore its capabilities. In the future, we will surely make this product useful and beneficial to the world. We believe that the road ahead will definitely be able to make this achievement, and it will be a river of research, adding brilliant waves, and a chapter of science and technology.

Where to Buy 1-Bromo-4-Ethoxyl-2,3-Difluorobenzene in China?

As a trusted 1-Bromo-4-Ethoxyl-2,3-Difluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 1-Bromo-4-Ethoxyl-2,3-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-Bromo-4-Ethoxyl-2,3-Difluorobenzene?

1-Bromo-4-ethoxy-2,3-difluorobenzene is a crucial chemical raw material in the field of organic synthesis. It has a wide range of uses and can be used as a key intermediate in the field of medicinal chemistry to help create a variety of new drugs. Taking the synthesis of an antibacterial drug as an example, this compound can ingeniously introduce key functional groups through specific reaction steps, thereby constructing a complex molecular structure with antibacterial activity, providing a powerful weapon for humans to fight bacterial infections.
In the field of materials science, 1-bromo-4-ethoxy-2,3-difluorobenzene also plays an important role. It may participate in the preparation of polymer materials with special properties. By polymerizing with other monomers, the material is endowed with unique electrical, optical or mechanical properties. For example, when preparing optoelectronic functional materials, through reasonable design and reaction, the material can have excellent photoelectric conversion efficiency, laying the foundation for the research and development of new optoelectronic devices.
In addition, in the fine chemical industry, the compound can be used to synthesize high-end fragrances, dyes and other fine chemicals. By ingenious chemical modification and reaction, products with unique aroma or color can be created to meet the market demand for high-quality fine chemicals. In summary, 1-bromo-4-ethoxy-2,3-difluorobenzene has shown great application potential in many fields due to its diverse reactivity and unique structure, promoting the continuous development and progress of related industries.

What are the physical properties of 1-Bromo-4-Ethoxyl-2,3-Difluorobenzene?

1-Bromo-4-ethoxy-2,3-difluorobenzene is an organic compound with unique physical properties and is crucial in the fields of chemical industry and scientific research.
Looking at its properties, under normal temperature and pressure, 1-bromo-4-ethoxy-2,3-difluorobenzene is often in a colorless to pale yellow liquid state. When the texture is pure, it is clear and transparent, like a smart crystal liquid. Its olfactory experience is also unique, with a special aromatic smell. Although it is not rich and pungent, it is unique, allowing people to keenly sense its existence in a specific environment.
When it comes to the melting boiling point, this compound has a low melting point, about -20 ° C under standard pressure, which allows it to maintain a liquid state under normal low temperature conditions and has good fluidity. The boiling point is relatively high, about 210-220 ° C, indicating that a higher temperature is required to convert it from liquid to gaseous. This property allows it to maintain a stable liquid state in a certain temperature range of the reaction system, providing a good medium for related chemical reactions.
In terms of solubility, 1-bromo-4-ethoxy-2,3-difluorobenzene exhibits affinity for organic solvents. Organic solvents such as common ethanol, ether, and dichloromethane can be well miscible with it. This is because the molecular structure of the compound contains both hydrophobic aromatic rings and halogen atom parts, as well as ethoxy groups with certain lipophilic properties, so it can be uniformly dispersed in the molecular environment of organic solvents. However, its solubility to water is extremely low, and it is almost insoluble in water. Due to the significant difference between the polarity of water and the non-polar structure of the compound, the two are difficult to blend with each other.
Over the density, the density of 1-bromo-4-ethoxy-2,3-difluorobenzene is greater than that of water, which is about 1.5-1.6 g/cm ³. When mixed with water, it can be clearly observed that it sinks to the bottom of the water, and the stratification phenomenon is obvious. This property is of great significance for judging the phase distribution of substances and subsequent processing operations in separation and purification and related liquid-liquid reaction systems.
In addition, the vapor pressure of 1-bromo-4-ethoxy-2,3-difluorobenzene is low, and the volatilization rate is slow at room temperature, which makes it relatively small during storage and use due to volatilization, and also reduces the risk of high-concentration vapor formation in the air and causing safety problems to a certain extent.

Is 1-Bromo-4-Ethoxyl-2,3-Difluorobenzene Chemically Stable?

1-Bromo-4-ethoxy-2,3-difluorobenzene is an organic compound, and its chemical stability needs to be considered from many aspects.
From the perspective of chemical bonds, this compound contains carbon-bromine bonds, carbon-oxygen bonds and carbon-fluorine bonds. The carbon-bromine bond is relatively active. Because the electronegativity of the bromine atom is higher than that of carbon, the electron cloud is biased towards the bromine atom, which enhances the polarity of the carbon-bromine bond. In the nucleophilic substitution reaction, the bromine atom is easily attacked and left by the nucleophilic reagent.
The carbon-oxygen bond is relatively stable, and the oxygen atom is connected to the carbon atom by a covalent bond, and the stable structure is maintained by the common However, under certain conditions, such as strong acidic or alkaline environments, the carbon-oxygen bond may also break or participate in the reaction.
The carbon-fluorine bond energy is quite high, the fluorine atom is extremely electronegative, and the covalent bond formed with the carbon atom is extremely stable. This structural property makes the compound have certain resistance to some reagents under normal conditions, because the carbon-fluorine bond is not easy to break.
In terms of overall stability, under conventional ambient temperature and pressure conditions, 1-bromo-4-ethoxy-2,3-difluorobenzene can remain relatively stable without special reagents or conditions. However, when exposed to specific chemicals such as strong oxidizing agents, reducing agents, strong acids, and strong bases, or under extreme conditions such as high temperature and light, its chemical structure may change, triggering various chemical reactions.
In summary, the chemical stability of 1-bromo-4-ethoxy-2,3-difluorobenzene is not absolute, but depends on the specific environment and the chemicals it is exposed to.

What is the production process of 1-Bromo-4-Ethoxyl-2,3-Difluorobenzene?

The production process of 1-bromo-4-ethoxy-2,3-difluorobenzene is an important matter for chemical preparation. At the beginning of the process, it is often necessary to select suitable raw materials. Based on compounds containing benzene rings, such as p-ethoxylbenzene, it can be one of the starting materials.
The raw material is established, and the reaction step is the key. To introduce bromine atoms, bromination can be used. Under specific reaction conditions, such as suitable catalysts and reaction temperatures, bromine and raw materials can be substituted. This process requires fine regulation of temperature. If the temperature is too high or side reactions occur, the purity of the product will be affected; if the temperature is too low, the reaction will be slow and take too long.
As for the introduction of difluorine atoms, fluorine-containing reagents are often used to achieve this by means of nucleophilic substitution or other suitable reaction mechanisms. This step also requires careful control of the reaction conditions. The amount of fluorine-containing reagents and the reaction time are all about success or failure. The solvent used also needs to be considered to ensure that it is favorable to the reaction and compatible with the reactants and products.
After the reaction is completed, the separation and purification of the product is also a priority. The target product can be separated by distillation according to the difference in boiling points of different substances. Or by chromatography, the purpose of separation and purification can be achieved according to the different distribution coefficients of the substance in the stationary phase and the mobile phase.
The entire production process, from raw material selection to product refining, requires fine operation and strict control to obtain high-purity 1-bromo-4-ethoxy-2,3-difluorobenzene, which meets the needs of industry and scientific research.

What are the precautions for storing and transporting 1-Bromo-4-Ethoxyl-2,3-Difluorobenzene?

1-Bromo-4-ethoxy-2,3-difluorobenzene is also an organic compound. During storage and transportation, many matters need to be paid attention to.
First words storage. This compound should be placed in a cool, dry and well ventilated place. Cover its properties or be affected by changes in temperature and humidity. High temperature and humid places can easily cause chemical reactions and damage its quality. And it should be kept away from fires and heat sources to prevent the risk of fire and explosion. Because of its certain chemical activity, it can cause violent reactions in case of open flames, hot topics.
Furthermore, it needs to be stored separately from oxidants, acids, bases, etc., and must not be mixed. Due to its special chemical structure, it encounters with various chemicals, or causes unpredictable reactions, resulting in danger. The storage place should also be equipped with suitable materials to contain the leakage, in case of leakage, and can be dealt with in time to prevent its spread from causing greater harm.
As for transportation, it is necessary to ensure that the container is well sealed and there is no risk of leakage. During transportation, it is necessary to prevent exposure to the sun, rain, and avoid high temperature environments. The selected transportation vehicles should have corresponding safety protection equipment and emergency treatment measures. The escort personnel also need to be familiar with the characteristics of this compound and emergency treatment methods. In case of emergencies, they can respond in time. When transporting, do not mix with contraband substances, follow relevant transportation regulations and standards, and act with caution to ensure the safety of the transportation process. Only in this way can 1-bromo-4-ethoxy-2,3-difluorobenzene be properly stored and transported to avoid accidents.